LOCUS       BGC0002410             19843 bp    DNA     linear   BCT 17-MAY-2022
DEFINITION  Parafrankia sp. CH37 Contig1, whole genome shotgun sequence.
ACCESSION   BGC0002410
VERSION     BGC0002410
KEYWORDS    .
SOURCE      Parafrankia sp. CH37
  ORGANISM  Parafrankia sp. CH37
            Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
            Parafrankia.
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from University Laval, Prof.
            Damase P. Khasa.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:39:01
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..948
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 426.2;
                     E-value: 1e-129)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006544531.1"
                     /locus_tag="IHE48_18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="MBE3202939.1"
                     /transl_table=11
                     /translation="MRVVMFGYQTWGHRTLQALLDSHHDVALVVTHEKSDHAYEKIWDD
                     SVADLATEHGVPVAIRNRPDDEDLLSLLKETDPDAIVATNWRTWIPPQVFNLPRLGTLN
                     IHDSLLPAYAGFAPLIWALINGEPEVGVTAHIMSDELDAGDVVLQHRVPVGPRDTTTDL
                     FHRTLALFGPMAVEGLDLMASGRTDWAPQDRSKASFFHKRSERDSLIDWTWTAEELDRL
                     VRAQCDPYPNAFTYRNGERVRIVSAEVSKGCYGGTPGRIFIREGDGVVIVAGAQARHGR
                     SHGLLIRTVRLDDGRELAATDYFTTMGGYLTDRA"
     protocluster    1..19843
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4115:19843]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4116..19843
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
     protocluster    1..19843
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4115:9464]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4116..9464
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..19843
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..19843
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002410"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19843
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..948
                     /locus_tag="IHE48_18560"
     gene            complement(1074..2066)
                     /locus_tag="IHE48_18565"
     CDS             complement(1074..2066)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 270.2; E-value:
                     3.2e-82)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006544530.1"
                     /locus_tag="IHE48_18565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="MBE3202940.1"
                     /transl_table=11
                     /translation="MRGIARTLAALCVAGAVMTGLVACGDDDDSGSTQADTAAAAGFPV
                     TIEHKFGSTTIDKAPTRIIALSYEEDTLATLGITPIAYATNPYKEDGKFPWLDGKIDLA
                     KSTGLDTSGDLNLEQIASLKPDLILATNFYGLEDYYDRLSEIAPTVAYKTEAGIATWQE
                     VSTTIGKAVGREADVAKAVAATEKSITDTAAKLPGLKDKTFSYSFYYDANGLAVIDDPE
                     TVSIQLYSQLGMKLSPKVTASVVDRELSLEKVGELDADFLLIGYATDELRTQMDANDLF
                     KKIPAVVDGRALEVDAFTAGAVNNPTILNIPWQLEQLESTLEKVAGTSG"
     gene            complement(2314..4119)
                     /locus_tag="IHE48_18570"
     CDS             complement(2314..4119)
                     /NRPS_PKS="Domain: AMP-binding (61-504). E-value: 1.8e-78.
                     Score: 255.7. Matches aSDomain:
                     nrpspksdomains_IHE48_18570_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     441.9; E-value: 4e-134)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006544529.1"
                     /locus_tag="IHE48_18570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="MBE3202941.1"
                     /sec_met_domain="AMP-binding (E-value: 4e-88, bitscore:
                     285.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPSTTDRPDGQLDAHPEGQPDGQPGGGAAGPGWNRWPAEFVER
                     YQEAGYWGDRTLDELLREWARRSGPATALVCGDRRISYAELDEAVDDLAAGLASIGIGP
                     GDHLVVHLPNRAEFVTTLFALMRRGAIGILALPAHRRVEIEHFASLAGAVGYVIADRFE
                     GFDYRELARQVTEAVPSVRHVLVAGEPGPYTGLDALASAGRSTRLAAAPSAATATATAD
                     AAAADATAGGATAGGATAGGATVPGRDPGDIAVLLISGGTTGKPKLIPRTHRDYAYNAR
                     ASAEVCRLTAADVYLVALPAAHNFPLACPGILGAFTVGASAVMALSSSPDAVFDLISRE
                     RVTVTAAVPPLARLWVEAAGWEGPDTTSLRLLQVGGAKLDEGLARRITPTLGAGVQQVF
                     GMAEGLLNYTRLDDPDETVFTTQGRPLAEADEVRVLDGSGYEVPAGQVGELWTRGPYTI
                     RGYYRAAAHNATVFGADGFFRTGDLVRQLPTGHLVVEGRVKDVINRGGENVSAGELEEH
                     LQTHPAVAQVAVVGLPDPDVGESVCAVVVAAPGGAPRLKEIKNYLRDRGLARFMLPDRL
                     EVMDGFPYTAVGKIDKRELRNRLDQ"
     aSDomain        complement(2608..3936)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IHE48_18570_AMP-binding.1"
                     /evalue="1.80E-78"
                     /label="IHE48_18570_AMP-binding.1"
                     /locus_tag="IHE48_18570"
                     /protein_end="504"
                     /protein_start="61"
                     /score="255.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="REWARRSGPATALVCGDRRISYAELDEAVDDLAAGLASIGIGPGD
                     HLVVHLPNRAEFVTTLFALMRRGAIGILALPAHRRVEIEHFASLAGAVGYVIADRFEGF
                     DYRELARQVTEAVPSVRHVLVAGEPGPYTGLDALASAGRSTRLAAAPSAATATATADAA
                     AADATAGGATAGGATAGGATVPGRDPGDIAVLLISGGTTGKPKLIPRTHRDYAYNARAS
                     AEVCRLTAADVYLVALPAAHNFPLACPGILGAFTVGASAVMALSSSPDAVFDLISRERV
                     TVTAAVPPLARLWVEAAGWEGPDTTSLRLLQVGGAKLDEGLARRITPTLGAGVQQVFGM
                     AEGLLNYTRLDDPDETVFTTQGRPLAEADEVRVLDGSGYEVPAGQVGELWTRGPYTIRG
                     YYRAAAHNATVFGADGFFRTGDLVRQLPTGHLVVEGRVKDVINR"
     CDS_motif       complement(2704..2793)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18570_0001"
                     /evalue="2.80E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="IHE48_18570"
                     /protein_end="472"
                     /protein_start="442"
                     /score="16.5"
                     /tool="antismash"
                     /translation="PAGQVGELWTRGPYTIRGYYRAAAHNATVF"
     gene            complement(4116..9464)
                     /locus_tag="IHE48_18575"
     CDS             complement(4116..9464)
                     /NRPS_PKS="Domain: PP-binding (490-550). E-value: 3.9e-13.
                     Score: 41.7. Matches aSDomain:
                     nrpspksdomains_IHE48_18575_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (647-946). E-value:
                     6.2e-111. Score: 362.4. Matches aSDomain:
                     nrpspksdomains_IHE48_18575_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (1110-1520). E-value:
                     4.4e-97. Score: 317.1. Matches aSDomain:
                     nrpspksdomains_IHE48_18575_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1648-1717). E-value: 1.8e-21.
                     Score: 68.0. Matches aSDomain:
                     nrpspksdomains_IHE48_18575_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: SalSyn"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 322.4; E-value:
                     1e-97)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011605288.1"
                     /locus_tag="IHE48_18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="MBE3202942.1"
                     /sec_met_domain="SalSyn (E-value: 8.3e-157, bitscore:
                     512.7, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.3e-46, bitscore:
                     146.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-107, bitscore:
                     347.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-15, bitscore:
                     46.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRPDRHRRIVPFGQQPAAVAARLARSATGPFVVYERAGEWSFG
                     TGVLAEIELRAHELRHRTGAGQWQVEPTGPAPLRQVAGILAGLDIAGWRAYGWAAFELS
                     HLLAGLAVPTGDAPLLHLIVPRQEARLLDGVATLRTLAAAAIPPATGGLADSSEQAALA
                     ELAELVTGGAVDAPSAAGPLAVADLEHGVDGYRQAVATAVADIHAERLRKVILSRVVPV
                     EGDIDLVATYEAGRAGNTPARSFLLDVGYLRATGFSPETVVEVSADGLVSTQPLAGTRA
                     LTGDAATDRGLRDVLLSDPKEIYEHAVSVQACQEELRRFCRPGSVAVDEFMTVLERGSV
                     QHLASRVAGRLAVGRDAWDAFGTVFPSITASGVPKAAACEAITGYESEPRGLYSGAVLT
                     VDADGSLDAALVLRTVFQHEGRTWLRAGAGIVAQSEPDREAEETREKLRSVSRFLVTAA
                     PAAPAAQAAPAAPAPRTVAAAATAGPALAQDIDAVRAIVAQMLDEEPEDVGYEANLFEL
                     GLESIALMKAVGRWRQAGVAVSFGELAENPTVDGWFKILSARMPSAPASDAPPAGAPSA
                     VTTPPAGIAPAGLPPAGAPPAGEAVTAISPSPVGEPAEAPADADGDTAADTGLDLNLST
                     GTGTADADTDTDDAEFPLALMQHAYWVGRDGGQPLGEVAAHLFTEFDGQDVDPDRLRGA
                     VERLVARHDMLRVRVTDNGAQIVEEHSGWRGLTVHDLRALDEPTVRARLDEIRDRMSHE
                     MLDIESGEVFATALSLLPAGRTRLHLDVDMVAADAVSFRVLLADLARFYDQPQEVLPPL
                     GYSYREYRAARAAERTAAARAAAEWWQGRLPSLPGAPGLPRVADAAGSRGRPSVARRHF
                     VLPPAARDALRAAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFDREPVHPDIN
                     QVVGDFTSSVLLEVDVTEDLPFAARVRQIQARLHADAAHAEYSGVEVLRDLTRRTGEQV
                     LAPVVFTSALGLGELFDAGVRRLFGDPVWIISQGPQVLLDAQVTEIDGGLLINWDVRED
                     EFPAGAVDGMFGAFERLVRDLATAGEAWDVPVDGLLPAATGEIRRAVNETAGRVPTRLL
                     HEGFFERAVCAPGAPALVWDDTAGAPGRGELSYGELRRRALSLAGALVGHGVRRGDLVG
                     VSLPKGPSQVVAVLGVLAAGATYVPVGVEQPPARVERIATAAGFGVLITEAPRDGVPAG
                     VVQIAPDQAARPDPAVQPLPVPDLLAPAELGGLDRPAYVLFTSGSTGQPKGVEVGHRAA
                     ANTIEDLIDRLGLGADDRTLAVSALDFDLSVFDLFAPLSVGGAVVLLDEESRREAHRWA
                     ELVRDHRVTILNCVPTVLDLVLSAGVDLGPTLRAVLLGGDRVGVDLPGRLDAAVPGCRF
                     LGLGGTTETAIHSTICEVVGTEPVPDWWRSVPYGTPLRNVRLRVVDPLGRDCPDHVTGE
                     LWIGGDGVARGYLGDPQRTADRFVEYGGLRWYRTGDLARYQPDGTVEFLGRRDHQVKIR
                     GFRVELGEVEAALDTLEQVRAGVAVLVEGAAGHPAALGAGVVPVDTAGGDAVGADAAGT
                     DLAGTELATAVREGLRGMLPPHMVPDLVVTLDTLPLTANGKIDRKAVTAAVRHALGAGT
                     GEHTPPRGDLEQVVFNVWREVLGVPEFGVTDEFFALGGDSVLATAVVRRLRDELDTAAV
                     TVRSLFAAPTVATLAERIRAADPVPGRADRVAAIALEIAAMTDAEVAAALGGEATDLTA
                     PGLDQPGLDEQPGLEQPGLDEPGGAR"
     aSDomain        complement(4314..4520)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IHE48_18575_PCP.1"
                     /evalue="1.80E-21"
                     /label="IHE48_18575_PCP.1"
                     /locus_tag="IHE48_18575"
                     /protein_end="1717"
                     /protein_start="1648"
                     /score="68.0"
                     /tool="antismash"
                     /translation="EQVVFNVWREVLGVPEFGVTDEFFALGGDSVLATAVVRRLRDELD
                     TAAVTVRSLFAAPTVATLAERIRA"
     aSModule        complement(4314..7523)
                     /complete
                     /domains="nrpspksdomains_IHE48_18575_Heterocyclization.1"
                     /domains="nrpspksdomains_IHE48_18575_AMP-binding.1"
                     /domains="nrpspksdomains_IHE48_18575_PCP.1"
                     /locus_tags="IHE48_18575"
                     /monomer_pairings="Ser -> Ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4875..4940)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0011"
                     /evalue="4.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="IHE48_18575"
                     /protein_end="1530"
                     /protein_start="1508"
                     /score="37.8"
                     /tool="antismash"
                     /translation="FLGRRDHQVKIRGFRVELGEVE"
     aSDomain        complement(4905..6134)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IHE48_18575_AMP-binding.1"
                     /evalue="4.40E-97"
                     /label="IHE48_18575_AMP-binding.1"
                     /locus_tag="IHE48_18575"
                     /protein_end="1520"
                     /protein_start="1110"
                     /score="317.1"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FFERAVCAPGAPALVWDDTAGAPGRGELSYGELRRRALSLAGALV
                     GHGVRRGDLVGVSLPKGPSQVVAVLGVLAAGATYVPVGVEQPPARVERIATAAGFGVLI
                     TEAPRDGVPAGVVQIAPDQAARPDPAVQPLPVPDLLAPAELGGLDRPAYVLFTSGSTGQ
                     PKGVEVGHRAAANTIEDLIDRLGLGADDRTLAVSALDFDLSVFDLFAPLSVGGAVVLLD
                     EESRREAHRWAELVRDHRVTILNCVPTVLDLVLSAGVDLGPTLRAVLLGGDRVGVDLPG
                     RLDAAVPGCRFLGLGGTTETAIHSTICEVVGTEPVPDWWRSVPYGTPLRNVRLRVVDPL
                     GRDCPDHVTGELWIGGDGVARGYLGDPQRTADRFVEYGGLRWYRTGDLARYQPDGTVEF
                     LGRRDHQVKIR"
     CDS_motif       complement(5013..5102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0010"
                     /evalue="5.30E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="IHE48_18575"
                     /protein_end="1484"
                     /protein_start="1454"
                     /score="50.7"
                     /tool="antismash"
                     /translation="PDHVTGELWIGGDGVARGYLGDPQRTADRF"
     CDS_motif       complement(5622..5681)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0009"
                     /evalue="7.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="IHE48_18575"
                     /protein_end="1281"
                     /protein_start="1261"
                     /score="27.8"
                     /tool="antismash"
                     /translation="AYVLFTSGSTGQPKGVEVGH"
     CDS_motif       complement(6333..6407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0008"
                     /evalue="1.30E-05"
                     /label="Cy7"
                     /locus_tag="IHE48_18575"
                     /protein_end="1044"
                     /protein_start="1019"
                     /score="18.1"
                     /tool="antismash"
                     /translation="ISQGPQVLLDAQVTEIDGGLLINWD"
     CDS_motif       complement(6522..6569)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0007"
                     /evalue="1.20E-05"
                     /label="afterCy5"
                     /locus_tag="IHE48_18575"
                     /protein_end="981"
                     /protein_start="965"
                     /score="17.9"
                     /tool="antismash"
                     /translation="DAAHAEYSGVEVLRDL"
     aSDomain        complement(6627..7523)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IHE48_18575_Heterocyclization.1"
                     /evalue="6.20E-111"
                     /label="IHE48_18575_Heterocyclization.1"
                     /locus_tag="IHE48_18575"
                     /protein_end="946"
                     /protein_start="647"
                     /score="362.4"
                     /tool="antismash"
                     /translation="DAEFPLALMQHAYWVGRDGGQPLGEVAAHLFTEFDGQDVDPDRLR
                     GAVERLVARHDMLRVRVTDNGAQIVEEHSGWRGLTVHDLRALDEPTVRARLDEIRDRMS
                     HEMLDIESGEVFATALSLLPAGRTRLHLDVDMVAADAVSFRVLLADLARFYDQPQEVLP
                     PLGYSYREYRAARAAERTAAARAAAEWWQGRLPSLPGAPGLPRVADAAGSRGRPSVARR
                     HFVLPPAARDALRAAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFDREPVHPD
                     INQVVGDFTSSVLLEVDV"
     CDS_motif       complement(6630..6689)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0006"
                     /evalue="1.70E-10"
                     /label="Cy5"
                     /locus_tag="IHE48_18575"
                     /protein_end="945"
                     /protein_start="925"
                     /score="32.8"
                     /tool="antismash"
                     /translation="HPDINQVVGDFTSSVLLEVD"
     CDS_motif       complement(6690..6728)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0005"
                     /evalue="1.30E-03"
                     /label="afterCy4"
                     /locus_tag="IHE48_18575"
                     /protein_end="925"
                     /protein_start="912"
                     /score="11.5"
                     /tool="antismash"
                     /translation="FVLNVPMFDREPV"
     CDS_motif       complement(6741..6800)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0004"
                     /evalue="4.10E-09"
                     /label="Cy4"
                     /locus_tag="IHE48_18575"
                     /protein_end="908"
                     /protein_start="888"
                     /score="29.0"
                     /tool="antismash"
                     /translation="GVTPAMAVATAFAEVLAGWS"
     CDS_motif       complement(7095..7139)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0003"
                     /evalue="1.00E-03"
                     /label="Cy3"
                     /locus_tag="IHE48_18575"
                     /protein_end="790"
                     /protein_start="775"
                     /score="12.4"
                     /tool="antismash"
                     /translation="RLHLDVDMVAADAVS"
     CDS_motif       complement(7320..7373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0002"
                     /evalue="2.90E-08"
                     /label="Cy2"
                     /locus_tag="IHE48_18575"
                     /protein_end="715"
                     /protein_start="697"
                     /score="25.9"
                     /tool="antismash"
                     /translation="LVARHDMLRVRVTDNGAQ"
     aSDomain        complement(7815..7994)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_IHE48_18575_PP-binding.1"
                     /evalue="3.90E-13"
                     /label="IHE48_18575_PP-binding.1"
                     /locus_tag="IHE48_18575"
                     /protein_end="550"
                     /protein_start="490"
                     /score="41.7"
                     /tool="antismash"
                     /translation="DAVRAIVAQMLDEEPEDVGYEANLFELGLESIALMKAVGRWRQAG
                     VAVSFGELAENPTVD"
     CDS_motif       complement(8202..8231)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_IHE48_18575_0001"
                     /evalue="9.60E+00"
                     /label="Cy2"
                     /locus_tag="IHE48_18575"
                     /protein_end="421"
                     /protein_start="411"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="LRTVFQHEGR"
     gene            complement(9461..9721)
                     /locus_tag="IHE48_18580"
     CDS             complement(9461..9721)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 113; E-value: 6.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545290.1"
                     /locus_tag="IHE48_18580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MbtH family protein"
                     /protein_id="MBE3202943.1"
                     /transl_table=11
                     /translation="MSTNPFDDESGSFFVLVNSEGQHSLWPGFAAVPAGWTVVHGEETR
                     QSCLDYVEAHWTDLRPLSLVAQMDSDARAGEVARSDASASR"
     gene            complement(9814..11745)
                     /locus_tag="IHE48_18585"
     CDS             complement(9814..11745)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 284.4; E-value:
                     3.1e-86)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545289.1"
                     /locus_tag="IHE48_18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="MBE3202944.1"
                     /transl_table=11
                     /translation="MLHEDPATAGALRQAWRHLRPHRRLLTAALAATVASTAAVVGIAP
                     VIGRGVDAVIARDRTALWWTVGGLIVLVLARLLLLRWSEVLLARAGERVVQDLRDLVVE
                     RLAGAPLRFVEAHRTGDLLRRATGEIADLALFIREQLPNLLGIGLTVVLTTVLLIVYSP
                     LLSLVLVVLFIPAAVAVVRWFDQVARTAFGRQASADATMTATFTETLAASEALVVVGRP
                     GEWVERFRRDNDELLRASNRTIGAQNRLELFSLLEGLATAVLLLLSVWLARSGHLGVGT
                     VVVFVLATRNLFEGLAGLSRLIGQLQTARVGVARLADLLEATDATGTDAPGTDSAAIDL
                     PATAASATAVSATAVSATAASATGAPASDAPTAGGGAVSLPPRGELAATDLRFGYGTDE
                     DAQVLRGVSVRFPSGDRAGLVGTTGSGKTTLAKLLCGLYEPDAGVVTFGGVDLSTVSPE
                     EIRRHVVLVPQQVHIITGSLAENLALAPGEPDRAAMERAVEVLGLTEWVAGLPGGLDAS
                     LGARGELLSAGERQIVGLVRAALVDPPVLVLDEATADLDPDVARRLETAVEHLRPGRTL
                     IVIAHRQATIDRLPRRVRLVSGRLVAGDTAGETAGDVRGAVGGDVLVDAGHSVPSQLQS
                     DPIVSDPA"
     gene            complement(11753..13546)
                     /locus_tag="IHE48_18590"
     CDS             complement(11753..13546)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 494.3; E-value:
                     7.9e-150)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545288.1"
                     /locus_tag="IHE48_18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="MBE3202945.1"
                     /transl_table=11
                     /translation="MAMSAGNTVLWAQLRSMPGPLSLGVLATLVQQLAMLVLPWGIQHA
                     LDDGITPLDVDQTVRWSLITAGISLAFLVGGVGGQWWSGIAANRVAHGLRSGLIDKVTT
                     LDRPALVGFGRGDLVMRVTRDVDLVRLWLQNLGVWVRVIVTLVVVLPAIGLLDPLLLLV
                     TVVTVPLVGLANAFFPGRYDTANEALSEAHGSRADAVEDLLSASAAVRGLGGERVLVRR
                     HHDLSRSVTSTSLRVAEVSAWWSAVPPALPRLAIAVGLGIGGAAAIRGDLTIGGLVAFT
                     SWMTTLALAIAILVDLLAGRGQARVAAERIAEVLGTPGLAEDPAAVVPLPATGALRVEG
                     AVVRHGDRHVLGPADLCAAPGEFIAVTGPTGSGKSTLARLLCRIEDPTEGTIRYGGVDL
                     RAASRTEVLTRIGLVPQRPLVLTGTIADNLRLGREIELAELRAACHAAALDEFIMSLPD
                     QYDTVVGERGGTLSGGQGQRLALARGLLGRPAVLVLDDVTSALDVETEAAVLRRLREWN
                     PTGAIVVVSHRPAVLDAADRVLTLPPPSRNTAPPGAEREPASAAESSSAAAAEPAAAAE
                     FSGGAAPSAGAADLTAGGHRG"
     gene            complement(13783..14922)
                     /locus_tag="IHE48_18595"
     CDS             complement(13783..14922)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 299.8; E-value: 3.5e-91)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545287.1"
                     /locus_tag="IHE48_18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="MBE3202946.1"
                     /transl_table=11
                     /translation="MATGVTGAAGLPGAAGGVLPPGGVLPPGGVLPGGVVPRGWVIRDR
                     GDRVSLRVDGRGVLVCLGLVVAIGVVSVLTLTTGDYHLSVREVVDSLLGQGSSGTDFIV
                     RTLRLPRLVAGLLVGAALAVSGAIFQTMTANPLGSPDVIGFTAGSATGAVIVILVLHGS
                     VYETSFGAIAGGVLTAVAIYLLSFRRGVAGPRLILIGIGVASMLTALNAYLIARATLGD
                     AITAQTWLLGSLSRRSWEQVRPLVFAVIVLLPAALYLSRRLSMLAMGADTARALGVSVE
                     SSRLALLGVGAALASCATAAAGPIGFVALAAPQLARHLARSAGAALLPAALLGALLVVA
                     SDLVAQRAFAPSQLPVGVATNAVGGLYLVWLLARQRRRI"
     gene            complement(15006..16082)
                     /locus_tag="IHE48_18600"
     CDS             complement(15006..16082)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 305.4; E-value: 7e-93)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545286.1"
                     /locus_tag="IHE48_18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="MBE3202947.1"
                     /transl_table=11
                     /translation="MSTGPSAGLSASPSAGRSTDPSASGTARGALRPLGLVAAVVLLAG
                     AVLMSIAVGANHLALSDVWRVLWHDDRSEAAVIVHDMRVPRTLVGLVVGAGLGVAGALA
                     QALTRNSLADPGLLGVNLGAAAAVVAAVSFLGVTSPSGYVWFALLGAAAASAAVYVLGA
                     TGRAAVAPERLIVAGAALSAVLAAFTYAVAFLDHETFDRLRFWDVGSLARADMPQLAVV
                     VPFIGVGLLVAFAIGGALNAMAMGEDAGRGLGVHVARTRTLGVLAVALLCGAGTAAAGA
                     ITFVGLGVPHIARAICGPDQRWVVAYSAVLGPVLLLTADVVGRVIIAPAELEVGVVSAF
                     VGAPVFIVLCRRARLGRL"
     gene            16481..17461
                     /locus_tag="IHE48_18605"
     CDS             16481..17461
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 198.2; E-value:
                     2.6e-60)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006545285.1"
                     /locus_tag="IHE48_18605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="MBE3202948.1"
                     /transl_table=11
                     /translation="MDSQPAVDSQPDGEPRLHARDLTLAYDQRVVATDLGVRIPDNSFT
                     VIVGPNACGKSTLLRALARMLRPRHGAVYLDGALIRSLPSKEVARRLGLLPQTSIAPSG
                     ILVSDLVARGRYPHQRLLRQWSRQDEDAVRDALAATHTEDLADRFVDELSGGQRQRVWL
                     AMALAQQTPIMLLDEPTTFLDLAHQIEILDLCADLHEESNRTLVAVLHDLNQACRYATH
                     LVAMKDGRIVAQGDPNEIVTAELVEEVFGISCSVVPDPETATPLVVPAARARRRELREN
                     LAIAEQARPRSHAADTDSDSDSDGAAGADPSGDAASGKAVAVSAG"
     gene            complement(17531..18015)
                     /locus_tag="IHE48_18610"
                     /pseudo=""
     CDS             complement(17531..18015)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643395.1"
                     /locus_tag="IHE48_18610"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="chorismate-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSASTTRTRHGRSAGCGAEPETDRRRAAALPASAKGLHEHAVVVD
                     AVADALAAWAWPSRRPRRPCCVGLAVPAAPTLIRTATMWHLPTRISGWLVDL"
     misc_feature    complement(17713..17715)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18452..19843
                     /locus_tag="IHE48_18615"
     CDS             18452..19843
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Orn_monoox"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 537.1;
                     E-value: 4.3e-163)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006542984.1"
                     /locus_tag="IHE48_18615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="MBE3202949.1"
                     /sec_met_domain="Orn_monoox (E-value: 2.7e-181, bitscore:
                     592.5, seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.8e-10, bitscore:
                     29.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRPPTAELGVHDVIGVGFGPSNIALGIAIQEHNSSVSAGAALR
                     AIFLERQPRFGWHRGMLLDGATMQVSFLKDLATLRNPSSSFSFLNYLHSQNRLVDFINH
                     KTMFPLRHEYHDYLEWAAGRLDYLVEYDTEVVDLRPVVHEGVVAYIDVISGRPGQPGRT
                     VVRRARNVVIAAGLEPRLPENAELGDRLWHNHDLLHRLAQMPSTPRQRFVVVGAGQSAA
                     EVTEHLHTRFPQAEVFAVFARYGLTPADNSGFVNQIFDPDAVDEFYHAPEGVREMLLTY
                     HRSTNYAAVDMDLIDELYRRSYQEKVRGPQRLYFLRASQVEAYEALPDGTRVHIRHLPT
                     GDKRVLDTDIVVLATGYNARDPRRVLGSMEDACLVSDSGRLQVARDYSIETKPDTTAGI
                     YVPGASEFQHGISSSLLSNISIRAGEILDSVLRRQELEEPLAAIGQGITAPSYLPAQHK
                     AQPQN"
ORIGIN
        1 atgcgggtcg taatgttcgg ataccagacc tgggggcatc gcacgctgca ggctcttctc
       61 gactcccatc acgacgtcgc cctggtcgtg acgcatgaga agagcgacca cgcgtacgag
      121 aagatctggg atgactcggt ggccgacctc gccaccgagc acggcgttcc cgtggcgatt
      181 cgcaaccggc ctgacgacga ggacctgctg tcgctgctca aggagaccga tcccgacgcc
      241 atcgtcgcca ccaactggcg gacctggatc ccgccgcagg tcttcaacct gccgcggctg
      301 ggaacgctga acatccacga ctcgctgctg cccgcctacg ccgggttcgc gccgttgatc
      361 tgggcgctga tcaacgggga gcccgaggtg ggcgtgacag cgcacatcat gagcgacgag
      421 ctcgacgccg gtgacgtcgt cctgcagcac cgggtgccgg tcggcccgcg tgacaccacc
      481 accgacctgt tccaccgcac cctcgcgctg ttcgggccga tggcggtcga gggcctggac
      541 ctgatggcca gcggccgcac cgactgggct ccccaggacc gttcgaaggc cagcttcttc
      601 cacaagcgct cggagcggga cagcctcatc gactggacct ggaccgccga ggagctcgac
      661 cggcttgtgc gcgcccagtg cgacccctat cccaacgcgt tcacctaccg caacggcgag
      721 cgggtccgca tcgtctccgc cgaggtctcc aagggctgct acggcggcac gcctggacgg
      781 atcttcatcc gcgagggtga cggcgtggtc atcgtcgcgg gcgcgcaggc acggcatgga
      841 cgcagccacg gactactgat ccgcaccgtg cgcctggacg acggccgcga gctggcggcg
      901 acggactact tcacgaccat gggcgggtac ctcaccgacc gggcctagat ctgcggcagt
      961 gaaaccgggc ggcacgcgct tgtctgcgta ccgcccggtt tccgcgttca ttcggtgctg
     1021 tgcctgttta tctgtgctgc cgtgtcccaa tccgtgccgt gcggaccggc acgtcagccg
     1081 gaggtgccgg cgaccttctc gagggtcgac tcaagctgct cgagctgcca cgggatgttc
     1141 aggatggtcg ggttgttgac cgcacccgcg gtgaatgcgt ccacctccag cgcacgaccg
     1201 tccacgaccg ccggaatctt cttgaacagg tcgttcgcgt ccatctgggt gcgcagctcg
     1261 tccgtggcgt acccgatcag caggaagtcg gcgtcgagct cgccgacctt ctccaggctc
     1321 agttcgcggt cgacgacact ggccgtcacc ttcggcgaga gcttcatgcc gagctgggag
     1381 tacagctgga tggagacggt ctccgggtcg tcgatcaccg cgaggccgtt ggcgtcgtag
     1441 tagaagctgt agctgaatgt cttgtccttc agcccgggaa gcttcgccgc ggtgtcggtg
     1501 atgctcttct cggtggcggc gaccgccttg gcgacgtcgg cctcacgccc gaccgccttg
     1561 ccgatcgtcg tgctgacctc ctgccaggtc gcgatgccgg cctcggtctt gtaggcgacc
     1621 gtcggcgcga tctcggagag ccggtcgtag tagtcctcga gcccgtagaa gttggtggcg
     1681 aggatgaggt ctggcttcag cgaggcgatc tgctcgaggt tgaggtcgcc gctggtgtcc
     1741 agacccgtgc tcttggcaag gtcgatcttg ccgtcgagcc aggggaactt cccgtcttcc
     1801 ttgtaggggt tcgtcgcgta ggcgatcggc gtgatgccga gcgtcgccaa cgtgtcctct
     1861 tcgtagctca aggcgatgat tctcgtcggc gccttgtcaa tcgtcgtaga accgaacttg
     1921 tgctcgatgg ttaccgggaa accggcggcc gccgcggtat ccgcctgggt cgaaccgctg
     1981 tcgtcgtcat ccccacaggc caccagcccg gtcatgaccg caccggcaac acacagtgct
     2041 gccagtgtgc gcgctattcc ccgcactaca gtcctcagcc ttccgccctc gccacgccag
     2101 cgcgacgatt cgcttgatcg aataaaattt tggttagctt aacctaaatc gttgccagga
     2161 caacaggtgc gatcaagccg aaacgcacct ggcgcgggtc agggccggcc acgagttcgc
     2221 tcccttcggg agcaggtcag taggtcgcgg gcaggcctcg acgtgcgaat gtcgggcgcg
     2281 gcccacaccg ggcgggtctg cgacgggaag ggctcactgg tcgagccggt tccgcagctc
     2341 ccgcttgtcg atcttcccga cggcggtgta ggggaacccg tccatgacct cgagccggtc
     2401 gggaagcatg aaccgggcca ggccgcggtc ccgcagatag ttcttgatct ccttgagccg
     2461 gggcgcgcca cccggggccg cgacgacgac cgcgcagacg ctctccccga catcggggtc
     2521 gggcagcccg acgaccgcca cctgggcgac cgcgggatgg gtctgcaggt gctcctccag
     2581 ctcaccggcc gagacgttct ccccgccgcg gttgatcacg tccttgaccc ggccctcgac
     2641 caccagatgc ccggtgggca gctgacgcac gaggtcgccg gtgcggaaga agccgtcggc
     2701 accgaagacg gtcgcgttgt gcgccgcggc ccggtagtac ccgcggatgg tgtagggccc
     2761 gcgggtccac agctcaccga cctggccggc cggcacctcg tacccggacc cgtcgagcac
     2821 ccggacctcg tccgcctcgg ccagcggccg gccctgggtg gtgaagacgg tctcgtcggg
     2881 gtcgtcgagg cgggtgtagt tcagcagccc ctcggccatc ccgaagacct gctggacgcc
     2941 ggccccgagc gtcggcgtga tccgccgggc gaggccctcg tcgagcttgg cgccgcccac
     3001 ctggagcagg cgcaggctgg tggtgtccgg cccctcccac ccggccgcct cgacccacag
     3061 ccgtgccagc ggcgggacgg ccgcggtgac cgtcacccgc tccctgctga tcaggtcgaa
     3121 gacggcgtcc gggctggacg acagcgccat caccgccgac gcacccacgg tgaacgcgcc
     3181 gaggatcccc gggcaggcca gcgggaagtt gtgcgccgcc ggcagcgcga ccaggtagac
     3241 gtcggcggcg gtgagccggc acacctcggc gctggcccgg gcgttgtagg cgtagtcgcg
     3301 gtgggtgcgc gggatcagct tcggcttgcc ggtcgtcccg ccggagatga gcagcacggc
     3361 gatgtcgccc ggatcccgcc cggggacggt ggccccgcca gcggtagccc ctcctgccgt
     3421 agccccgcca gcggtggcat cggcagcggc ggcgtcggcg gtggcggtgg cggtggcagc
     3481 ggaaggcgcg gcggccagcc gggtggagcg gcccgccgag gccagcgcgt cgaggcccgt
     3541 gtacggaccg ggctcgcccg ccaccagaac gtgccgcacc gacggcaccg cctcggtcac
     3601 ctggcgggcc agctcccggt agtcgaaacc ttcgaaccgg tcggcgatga catacccgac
     3661 ggcgccggcc aggctcgcga agtgctcgat ctccacccgc cggtgggccg gcagcgcgag
     3721 gatgccgatc gcgccgcggc gcatcagcgc gaacagcgtc gtcacgaact cggcgcggtt
     3781 cggcagatgc accaccaggt ggtcaccggg gccgatgccg atcgaggcga gccccgcggc
     3841 gaggtcgtcc accgcctcgt cgagctcggc gtagctgatt cgccggtccc cgcagaccag
     3901 cgcggtggcc ggcccggacc ggcgggccca ctcccgcagc agctcgtcca gcgtccggtc
     3961 gccccagtag ccggcctcct ggtaccgctc gacgaactcc gccggccacc ggttccaccc
     4021 cgggcccgcc gcgccgccgc cgggctggcc gtcaggctgg ccttcagggt gggcgtcgag
     4081 ctggccgtcg ggccggtcag tcgtcgacgg gacggtcacc gtgcgcctcc cggttcgtcg
     4141 agtcccggtt gttcgagtcc cggttgttcg tccagtcccg gttggtcgag tcccggtgcg
     4201 gtgaggtccg tcgcctcgcc gccgagcgcg gcggccacct ccgcgtcggt catcgccgcg
     4261 atctccaggg cgatcgcggc gacccggtcc gcccggcccg ggacggggtc ggcggcccgg
     4321 atccgctcgg cgagcgtcgc gacggtcggc gccgcgaaca gggagcggac ggtgaccgcg
     4381 gcggtgtcca gctcgtcgcg cagccgccgc accacggctg tggccaggac ggagtcaccg
     4441 cccagcgcga agaactcgtc ggtgacgccg aactccggca cgccgagcac ctcgcgccag
     4501 acgttgaaca cgacctgttc gagatcgccg cgcggcgggg tgtgctcccc cgtgcccgcg
     4561 cccagggcgt ggcgcacggc ggccgtcacc gccttgcggt cgatcttccc gttcgcggtg
     4621 agcgggaggg tgtcgagcgt gaccaccagg tcgggcacca tgtgcggcgg cagcatcccg
     4681 cgcaggccct cccgcaccgc ggtggccagc tccgtacccg ccagatccgt acccgcggcg
     4741 tcggcgccca ccgcgtcgcc gcccgcagtg tcgacgggga ccacgccggc tccgagcgcg
     4801 gcggggtggc cggcggcgcc ctcgacgagc accgccacgc cggcccgcac ctgctccagc
     4861 gtgtccagcg cggcctcgac ctcaccgagc tcgacccgga agccccggat cttgacctgg
     4921 tggtcgcgcc ggcccaggaa ctcgaccgtc ccgtccggct ggtagcgggc caggtcaccg
     4981 gtgcggtacc agcgcaggcc gccgtactcg acgaaccggt ccgcggtccg ctgcgggtcc
     5041 cccaggtacc cgcgggcgac cccgtcgcca ccgatccaca gctcgccggt gacgtggtcg
     5101 gggcagtccc ggccgagcgg gtcgaccacc cgcagccgca cgttgcgcag cggcgtgccg
     5161 tacggcaccg aacgccacca gtcgggcacc ggctccgtgc cgacgacctc gcagatcgtc
     5221 gagtggatgg ccgtctcggt ggtgccgccg agaccgagga agcggcagcc gggcaccgcg
     5281 gcgtccagcc ggccgggcag gtcgacaccg acccggtcgc cgccgagcag gacggcccgc
     5341 agcgtcgggc cgaggtccac cccggcggac aggacgaggt cgagcacggt gggaacgcag
     5401 ttgaggatgg tcacccggtg atcccggacg agctcggccc accggtgcgc ctcccggcgc
     5461 gactcctcgt cgagcagcac caccgcaccg ccgactgaca gcggcgcgaa caggtcgaac
     5521 accgacaggt cgaagtcgag ggccgacacc gccagcgtgc ggtcgtcggc accgaggccg
     5581 agccggtcga tcaggtcctc gatggtgttc gccgcggccc gatgcccgac ctcgaccccc
     5641 ttgggctggc cggtcgaccc ggatgtgaac agcacgtagg cgggccggtc cagcccgccg
     5701 agctccgcgg gcgccagcag atccggaacc ggcagcggct gcacagccgg gtcgggccgg
     5761 gcggcctggt cgggggcgat ctggacaacg ccggcgggga ccccgtcgcg cggcgcctcg
     5821 gtgatcagga cgccgaagcc ggcggcggtg gcgatgcgct ccacccgggc gggcggctgc
     5881 tcgacgccga ccggcacgta cgtcgcgccc gcggccagca cgccgagcac ggcgaccacc
     5941 tgggacggcc ccttgggcag gctgacaccg accaggtcac cgcgtcgcac gccgtgaccg
     6001 accagcgcgc cggccaggct cagcgcccgg cgccgcagct cgccgtagct gagctcgccc
     6061 cggccgggcg cgccggcggt gtcgtcccac accagcgcgg gcgcgccggg ggcgcagacg
     6121 gcccgctcga agaacccctc gtgcagcagc cgggtcggca cccgccccgc ggtctcgttc
     6181 accgcccggc ggatctcacc ggtcgccgcg ggcagcaggc cgtcgacagg gacgtcccag
     6241 gcctccccgg cggtggcgag atcccggacg agacgttcga aggcaccgaa catcccgtcg
     6301 acggcgccgg ccgggaactc gtcctcacgg acgtcccagt tgatcagcag gccgccgtcg
     6361 atctcggtga cctgcgcgtc caggagcacc tggggaccct gcgagatgat ccagaccggg
     6421 tcgccgaaga ggcggcgcac accggcgtcg aacagctcgc cgagcccgag ggcgctggtg
     6481 aacacgaccg gcgcgagcac ctgctcaccg gtgcggcggg tcaggtcgcg cagcacctcg
     6541 acgcccgagt actcggcgtg cgcggcgtcg gcgtgcagcc gcgcctggat ctggcgcacc
     6601 cgggccgcga acggcaggtc ctcggtgacg tcgacctcca gcagcaccga gctggtgaag
     6661 tcgccgacga cctggttgat gtcggggtgg accggctccc ggtcgaacat cgggacgttg
     6721 aggacgaacc tcgactcggt gctccacccg gcgaggacct cggcgaacgc ggtggccacg
     6781 gccatcgccg gggtgacgcc ccggctgtgc gcggccgcgc gcagggcgtc ccgggccgcc
     6841 ggcgggagga cgaagtggcg ccgtgccacc gacggccgtc cccgactgcc ggcggcgtcg
     6901 gcgacccggg gcaggccggg ggcgccgggc aggctcggca gccggccctg ccaccactcg
     6961 gccgccgctc gggcggcggc ggtgcgctcg gccgcccgcg cggcgcggta ctcgcggtag
     7021 ctgtagccca gcggcgggag aacctcctgc ggctgatcgt agaaacgggc gaggtcggcc
     7081 agcaggacgc ggaagctcac cgcgtcggcg gcgaccatgt cgacgtccag gtgcagtcgg
     7141 gtgcgccccg ccggcagcag gctcagcgcg gtcgcgaaga cctcaccgga ctcgatgtcg
     7201 agcatctcgt gcgacatccg gtcccggatc tcgtcgaggc gggcccgcac cgtcggctcg
     7261 tcgagggcac gcaggtcatg gacggtgagc ccacgccagc ccgagtgctc ctcgacgatc
     7321 tgggcaccgt tgtcggtgac ccgcacacgg agcatgtcgt gccgggccac cagccgctcg
     7381 actgcgccgc gcagccggtc ggggtcgacg tcctggccgt cgaactcggt gaacaggtgc
     7441 gcggcgacct cgccgagcgg ctggccgccg tcccggccga cccagtaggc gtgctgcatg
     7501 agcgcgagcg gaaactcggc gtcgtcggtg tccgtgtcgg cgtcggcggt gccggtgccg
     7561 gtgctgaggt tgaggtcgag gccggtgtcg gcggcggtgt cgccgtccgc atcggcgggg
     7621 gcttcggcag gctccccgac ggggctcggc gaaatcgccg tgacggcctc accggcaggc
     7681 ggcgcccccg cgggcggcag cccggcaggc gcgatcccgg caggcggcgt cgtcacggcg
     7741 gagggcgcgc cggcgggagg tgcgtccgac gccggggcgc tgggcatccg ggcggagagg
     7801 atcttgaacc agccgtccac ggtcgggttc tcggcgagct cgccgaacga gaccgcgacc
     7861 ccggcctgtc gccagcgtcc gaccgccttc atcagggcga tggactccag cccgagctcg
     7921 aacaggttcg cctcgtagcc gacgtcctcg ggctcctcgt cgagcatctg cgccacgatc
     7981 gcgcggaccg cgtcgatgtc ctgggccagc gcagggccgg cggtcgccgc ggcggccacg
     8041 gtccgcggag ccggtgcggc cggtgcggcc tgcgcggccg gcgcagctgg cgcggccgtg
     8101 acgaggaaac ggctgacgct gcgcagcttc tcccgggtct cctccgcctc acggtcgggc
     8161 tcggactggg cgacgatgcc ggcgccggcc cgcagccatg tccggccctc gtgctggaag
     8221 acggtgcgca ggacgagcgc cgcgtccagg gacccgtccg cgtcgacggt cagcaccgcc
     8281 ccgctgtaga ggccacgcgg ttcgctctcg tacccggtga tcgcctcgca ggcggctgcc
     8341 ttcggcaccc cggaggcggt gatcgacggg aagacggtcc cgaaggcgtc ccaggcgtcg
     8401 cggccgacgg cgaggcgccc ggcgacgcgg gaggccaggt gctggacgct gccgcgttcg
     8461 agcacggtca tgaactcgtc gacggcgacc gagccgggcc ggcagaagcg acgaagctcc
     8521 tcctggcagg cctgcacgga gacggcgtgc tcgtagatct ccttcggatc ggagagcagc
     8581 acgtcacgca gcccgcggtc ggtggcggcg tcgccggtga gcgcccgggt gccggccagc
     8641 ggctgggtgg agacgaggcc gtcggcgctc acctcgacca cggtctccgg gctgaagccg
     8701 gtcgcgcgca ggtagccgac gtccagcagg aaggagcgcg ccggggtgtt cccggcccgg
     8761 cccgcctcgt aggtggcgac caggtcgatg tcaccttcga cggggacgac ccgggagagg
     8821 atcaccttgc gcagccgttc ggcgtggatg tcggcgacgg ccgtggcgac ggcctgccgg
     8881 tacccgtcga cgccgtgctc gaggtcggcg acggcgagtg gaccggcggc gctcggggcg
     8941 tccacggcac cgcccgtgac cagttctgcc agctcggcca gcgccgcctg ctcggacgag
     9001 tcggccagcc cgcctgtcgc cggtgggatg gcggccgccg ccagggtgcg cagggtcgcg
     9061 acaccgtcga ggagccgagc ctcctgccgg ggcacgatca ggtgcagcag cggtgcgtcc
     9121 ccggtcggca cggcgaggcc ggcgagcagg tggctgagct cgaaggccgc ccagccgtag
     9181 gcccgccagc cggcgatgtc gaggccggcg aggatgcccg cgacctggcg cagcggcgcg
     9241 ggaccggtcg gctcgacctg ccactgcccg gcgcccgtgc ggtgacgcag ctcgtgcgca
     9301 cgcagctcga tctcggccag gacacccgtc ccgaaggacc attcgcccgc gcgctcgtac
     9361 acgacgaacg ggccggtggc ggagcgggcc agccgagcgg ctacggctgc gggctgctgg
     9421 ccgaacggga cgatcctgcg gtggcggtcg gggcgggtgg tcaccgggag gctgaagcgt
     9481 cggagcgggc gacttccccg gcacgggcgt cggaatccat ctgagcgacc aggctcagcg
     9541 gacgcagatc ggtccagtgg gcctcgacgt agtccaggca ggactgacgt gtctcctcgc
     9601 cgtgcacaac ggtccaaccc gccggaacgg cggcgaagcc cggccagagg gagtgctgac
     9661 cctcggagtt gaccagtacg aagaagctcc cgctttcgtc atcgaaggga ttcgtcgaca
     9721 tacccgccgt ctccttgatc gcaccagaac agttaggccg acctaagtcg gtataaggtg
     9781 aggttagcct aactaatgcg gtatgaccag cgattacgcc ggatcgctca caatcggatc
     9841 gctctgcagc tggctgggca cggaatgtcc cgcatcgacc aggacgtctc ccccgacagc
     9901 tccccggacg tctccagcgg tctctccagc ggtgtcgccc gcgacgagac ggccggagac
     9961 gaggcgaacc cgccgcggca ggcggtcgat ggtcgcctga cggtgcgcga tgacgatcag
    10021 cgtccgcccc gggcgcaggt gctccaccgc tgtctccagc cggcgcgcca cgtcggggtc
    10081 gaggtcggcc gtggcctcgt ccagcaccag caccggtggg tcgaccaggg ctgcccgcac
    10141 cagtccgacg atctggcgct cgcccgcgga cagcagctca ccgcgggcgc ccagggacgc
    10201 gtcgaggcca ccgggcagtc ccgccaccca ctcggtcaga cccagcactt ccaccgcccg
    10261 ctccatcgcc gcgcggtcgg gctcgcccgg cgccagcgcg aggttctccg cgagcgagcc
    10321 ggtgatgatg tgcacctgct gcggcacgag gacgacatgg cgccggatct cctcgggcga
    10381 cacggtgctc aggtcgacgc cgccgaacgt caccacgccc gcgtcgggct cgtagagacc
    10441 gcacaggagc ttcgcgagcg tcgtcttgcc cgagccggtg gtgccgacca gcccggcccg
    10501 gtcgccggac gggaagcgca ccgacacccc ccggagcacc tgcgcgtcct cgtccgtccc
    10561 gtagccgaac cgcaggtccg tcgcggcgag ctcaccgcgc ggcgggagcg acaccgcacc
    10621 accaccggcg gtgggcgcgt cggaggcggg cgcacccgtg gcggacgcgg cagtggcgga
    10681 cacggcagtg gcggacacgg cagtggcgga cgcggcagtg gcgggcagat cgatggcggc
    10741 ggaatcggtg ccaggcgcgt cggtgccagt cgcgtcggtg gcttccagca ggtcggccag
    10801 gcgggccacg ccgacccgcg cggtctgcaa ctgcccgatc aggcgggaca ggccggccag
    10861 gccctcgaac aggttgcggg tcgcgagcac gaacaccacg acggtgccca cgccgaggtg
    10921 accggaccgg gccagccaca cgctcagcag cagcagaacc gcggtggcca gtccctcgag
    10981 caggctgaag agctccagcc ggttctgcgc gccgatggtc cggttggacg cccgcagcag
    11041 ttcgtcgttg tcgcggcgga accgctcgac ccactcgccg ggacgtccga cgaccaccag
    11101 tgcctcgctg gcggccagcg tctcggtgaa cgtcgcggtc atcgtcgcgt cggccgaggc
    11161 ctgccggccg aacgccgtgc gggcgacctg gtcgaaccac cggaccaccg caaccgcggc
    11221 ggggatgaac agcacgacga gcaccagcga caacagcggc gagtagacga tcagcagcac
    11281 cgtcgtgagc accacggtga gcccgatgcc gagcaggttc ggtagctgtt cacggatgaa
    11341 cagcgccaga tcggcgatct cgccggtggc tcgccgcagc aggtccccgg tgcggtgcgc
    11401 ctccacgaac cgcagtggcg cgcccgcgag ccgctccacg acgaggtcgc gcaggtcctg
    11461 caccacccgt tcgccggccc gggccagcag cacctccgac cagcgcagga gcagcaggcg
    11521 ggcgagaacg agcacgatga ggccgccgac ggtccaccac agtgccgtcc ggtcgcgggc
    11581 gatcacggcg tcgacaccgc ggccgatcac gggggcgatc ccgaccacgg cggcggtgct
    11641 cgcgaccgtc gcggccaacg cggcggtcag cagccggcgg tgtggtcgca ggtggcgcca
    11701 cgcctggcgc aacgcgcccg cggtggccgg gtcctcgtgc agcatgcgga cctcagccac
    11761 ggtgacctcc ggcggtcaga tcagcggcac cagcggacgg cgcggcaccg ccagagaact
    11821 cggcagcagc agcgggctcg gcggcagcgg cagacgacga ctcggcagcg gaagccggct
    11881 cacgctcggc accgggcggc gcggtgttac gggagggcgg tggcagcgtc agcacccggt
    11941 cggcggcgtc cagcaccgcg ggccggtgcg acaccacgac gatcgcgccg gtgggattcc
    12001 attcccgcag ccggcgcagc accgccgcct cggtctcgac gtccagcgcc gaggtgacgt
    12061 cgtccagcac caggaccgcg ggacgcccca gcagcccgcg ggcgagcgcg agccgctggc
    12121 cctgcccgcc ggacagcgtg ccgccccgct cgccgaccac cgtgtcgtac tggtcgggaa
    12181 ggctcatgat gaactcgtcc agcgcggcgg cgtggcaggc ggcccgcagc tcggccagct
    12241 cgatctcgcg gcccagccgc aggttgtcgg cgatcgtgcc ggtgagtacg agcggccgct
    12301 gcggcacgag gccgatccgg gtcagcacct cggtgcgcga cgcggcccgc aggtccaccc
    12361 cgccgtagcg gatcgtcccc tcggtcgggt cctcgatccg gcacagcagc cgggccaggg
    12421 tggacttgcc cgatccggtc gggccggtga ccgcgatgaa ctcgccgggc gcggcgcaca
    12481 gatccgccgg cccgagcaca tggcggtcgc cgtggcggac cacggctccc tccacccgca
    12541 gggcgccggt ggccggcagc ggcaccacgg cggcggggtc ctcggccagc cccggggtgc
    12601 cgagcacctc ggcgatgcgc tcggcggcga cccgggcctg gccgcggccg gccagcaggt
    12661 cgaccaggat ggcgatggcc agcgcgaggg tcgtcatcca ggaggtgaag gcgaccaggc
    12721 cgccgatggt cagatcaccg cggatggcgg cggccccgcc gatgcccagg ccgaccgcga
    12781 tcgccagccg gggcaacgcc ggcggcaccg cggaccacca ggccgacacc tcggcgaccc
    12841 gaagggacgt gctcgtcacc gaccgggaca ggtcgtgatg gcggcggacg agcacccgct
    12901 cgccaccgag cccccgcacc gcggcgctgg ccgacagcag gtcctccacc gcgtccgcgc
    12961 gggagccgtg cgcctcggag agcgcctcgt tggcggtgtc gtaacggccg gggaagaacg
    13021 cgttggccag ccccaccagc ggcaccgtga cgacggtgac gagcagcagc agcgggtcga
    13081 gcagcccgat ggccggcagg acgaccacga gggtgacgat gacccggacc cagaccccga
    13141 ggttctgcag ccacagccgc accaggtcga cgtcccgggt gacccgcatg acgaggtcgc
    13201 cgcgcccgaa gccgaccagc gcgggccggt cgagggtggt caccttgtcg atgagcccgc
    13261 tccgcaggcc gtgcgcgacc cggttggccg cgatacccga ccaccactgg ccccccaccc
    13321 cgcccaccag gaacgcgagc gagatacccg cggtgatgag cgaccagcgc accgtctggt
    13381 cgacgtccag cggggtgatg ccgtcgtcca gggcgtgttg gatgccccag ggcagcacga
    13441 gcatcgccag ctgttggacg agggtcgcca gcacgccgag ggacagcgga ccgggcatgg
    13501 agcgcagctg cgcccacagg acggtgttgc cagccgacat ggccatcgcc aggaccactc
    13561 cagagtgggt gcccggcccg gccgggagcc gccgcggcgg agcgcccggc gctcgggtgc
    13621 gagcagagac ggggtcggga caccggcgac gagacagcgg cccgccgtcg ggcgaccgaa
    13681 acctaaggga gacaacaccg atatattagg taaagcttaa ctaagtgcct ggaacgggtc
    13741 aatcgatacg ccggcgtaac agcatccgcg cgggcaccgt gctcagatcc gccgccgctg
    13801 ccgggccagc agccacacca ggtagagacc gccgacggcg ttcgtcgcca ccccgacggg
    13861 cagctgcgag ggagcgaacg cccgctgggc caccaggtcg ctggccacca cgagcagcgc
    13921 gccgagcagc gccgccggca gcagcgccgc acccgccgac cgcgccagat gccgcgcgag
    13981 ctgcggcgcc gccagcgcga cgaaaccgat cgggcccgcc gccgcggtcg cgcaggacgc
    14041 gagcgccgca cccacaccga gcagcgcgag ccggctgctc tccaccgaca cgccgagcgc
    14101 ccgcgccgtg tccgcgccca tggccagcat cgacagccgc cggctcaggt agagcgcggc
    14161 cggcagcagc acgatcacgg cgaacaccag cgggcggacc tgctcccagc tgcgccggct
    14221 caggctgccc agcaaccagg tctgggccgt gatcgcgtca ccgagggtcg cccgcgcgat
    14281 caggtaggcg ttcagggcgg tcagcatcga cgccaccccg atcccgatca ggatcagccg
    14341 ggggccggcg acaccccgcc ggaacgacag caggtagatc gcgaccgcgg tcagcacacc
    14401 gccggcgatc gcaccgaagg acgtctcgta gacgctgccg tgcaggacca ggatcacgat
    14461 caccgctccg gtggccgacc cggcggtgaa accgatgacg tccgggctgc cgagcgggtt
    14521 ggccgtcatc gtctggaaga tcgccccgct gacggccagg gccgcgccga ccagcaggcc
    14581 cgccaccagt ctcggcagcc gcagcgtgcg gacgatgaag tccgtgccgg agctgccctg
    14641 cccgagcagg ctgtcgacca cctcgcggac cgacaggtgg tagtcacccg tcgtcagggt
    14701 caggacgctg accaccccga tagccacgac cagcccgaga cagaccagca ccccgcggcc
    14761 gtcgacacgc agcgacaccc ggtcacctcg gtcgcgaatc acccagccgc gtggcaccac
    14821 acccccgggc aggaccccac ccggcggcag gaccccaccc ggcggcagga ccccgcccgc
    14881 ggcgccgggc aggcccgccg ctccggtcac tcctgtcgcc atggactcac ctccccccgc
    14941 tgccgccccg ctggctccag tggccgcgcg cgtggtcatc gtcgccaccg cggggcgtgt
    15001 tccgctcaca atcgacccaa ccgtgcgcgc cgacacagca cgatgaagac cggggcgccg
    15061 acgaacgcgc tgaccacacc gacctccagc tcggcgggag cgatgatcac tcggccgacg
    15121 acgtcggcgg tgagcagcag caccgggccg agcacggcgg agtaggccac cacccagcgc
    15181 tggtccgggc cgcagatcgc ccgcgcgatg tgcgggacgc ccagccccac gaacgtgatg
    15241 gcgccggccg cagcggtgcc ggcgccgcac agcagagcga cggcgagcac ccccagcgtc
    15301 cgggtgcggg ccacgtggac cccgaggccg cggccggcat cctcgcccat ggccatcgcg
    15361 ttgagcgcgc cgccgatggc gaaggccacc agcaggccca cgccgatgaa gggcacgacg
    15421 acggcgagct gtggcatgtc ggcccgggcc agcgaaccga catcccagaa gcgcagccgg
    15481 tcgaacgtct cgtgatcgag gaaggcgacg gcgtaggtga aggcggcgag caccgcgctg
    15541 agcgcggcgc cggccacgat gagccgttcc ggcgcgacgg ccgcccggcc cgtggcaccc
    15601 agcacgtaga cggcggcgga ggcggcggcg gcgccgagca gcgcgaacca cacgtagccg
    15661 ctgggcgagg tcacacccag gaacgacacc gcggcgacga ccgcggcggc ggccccgagg
    15721 ttgaccccga gcaggcccgg gtcggcgagg gagttgcggg tcagcgcctg cgccagcgcg
    15781 ccggccaccc ccagccccgc gccgacgacg agcccgacga gggtgcgggg gacccgcatg
    15841 tcgtggacga tcacggcggc ctcggaccgg tcgtcgtgcc acagcacgcg ccagacgtcc
    15901 gacagcgcca ggtggttcgc accgacggcg atgctcatca gcacggcgcc ggcgagcagc
    15961 acgaccgcgg cgacaagccc caacggccgt agcgctcccc gcgccgtccc actcgcggac
    16021 gggtccgtgg accggccggc cgacgggctc gcggacagac cggccgacgg gccggtggac
    16081 atgcccgggc tccccacagc cgctgtggcc ggcgccctgg gccccgcgga aatcccgatc
    16141 accgttcccc gcttcacgac gttatttagg tcaggcttac ctctagtagt caacaccagt
    16201 gcgaatcgct cgggtgcgcg cggcgccagg aatcacgatg aggccttgac cagcaacgga
    16261 agcagcccac acgataagtg aggcttacct aaagagatcg gggttggtag aggccttgaa
    16321 cacacgacgt ggacagcgcc cggcatcgtt gcgcaggact gccgcatccg ccgacggcgg
    16381 cgaggggaaa gcaggcctgc cacagcgcag cgacgacggc ggttccacga cagcggccgc
    16441 ggtgtcgacc gccgcagcgg ccatggcgtc ccagccggcc gtggattccc agcccgccgt
    16501 ggattcccag cccgacgggg agccccggct gcacgcgagg gacctgaccc tcgcctacga
    16561 ccagcgcgtc gtcgccaccg acctcggtgt gcgcatcccc gacaactcct tcaccgtcat
    16621 cgtcggcccc aacgcctgcg gcaagtcgac cctgctgcgg gcgctggccc ggatgctgcg
    16681 cccacgccac ggcgcggtct acctcgacgg ggcgctcatc cggtcgctgc cgtccaagga
    16741 ggtggcgcgc cggctggggc tgctgccgca gacctcgatc gccccgagcg gcatcctcgt
    16801 ctccgatctg gtcgcccggg gccgctaccc ccaccagcgc ctgctgcgcc agtggtcccg
    16861 ccaggacgag gacgccgtcc gcgacgcgct cgcggccacc cataccgagg acctcgccga
    16921 ccggttcgtc gacgagctct ccggcggcca gcgccagcgg gtctggctcg cgatggcgct
    16981 ggcccagcag acgccgatca tgctgctgga cgagccgacg acgttcctgg acctcgcgca
    17041 ccagatcgag atcctcgacc tgtgcgcgga cctgcacgag gagagcaacc gaaccctcgt
    17101 cgccgtcctg cacgacctga accaggcctg ccggtacgcc acccatctgg tcgcgatgaa
    17161 ggacgggcgc atcgttgcac agggggaccc caacgagatc gtcaccgcgg agctggtgga
    17221 ggaggtcttc ggcatctcgt gcagcgtcgt gcccgacccc gagaccgcca caccgctggt
    17281 ggtgcccgcg gcccgggccc ggcgccgcga gcttcgcgag aacctggcga tagccgagca
    17341 ggcccggcct cggtcccacg ccgcagacac ggactccgac tccgactccg acggtgctgc
    17401 tggcgcagat ccctccggcg acgcggcgtc gggcaaggcc gtggcggtca gcgccggctg
    17461 acggccacgg ccttgcaggc tccagggcgg cggcggtgac agggatgcca gaggttccgt
    17521 ccgaggtgat ctcggcgcag cggatcgtca gtgcccactc cccgtcaccc tcggcatcac
    17581 accagcacca gccgacgaga ccgggtagca gcctcggtcg accggctcga ggtcgccgat
    17641 ggcggcacgg gccgcggacg tcggccaccc gcacaccgcc ggggtggggt gcagcgcggc
    17701 ggcgagacga agtaacgaca cctacagatc cacgagccaa ccgctgatcc gcgtcggcag
    17761 gtgccacatg gtcgcggtgc ggatgagcgt cggggccgcc gggacggcca ggcccacgca
    17821 gcaagggcgt cggggccgcc gggacggcca ggcccacgca gcaagggcgt cggcgaccgc
    17881 gtcgacgacg accgcgtgct cgtgcaggcc cttggcggag gcaggcagcg cggcggcccg
    17941 gcggcggtcg gtctccggtt cggcgccgca gcccgccgat cggccgtgcc tcgtcctcgt
    18001 cgtcgacgca gagatcttag gttaacttaa cctatacttt gcagggcgca accagtcaag
    18061 gcgccgagag ccatgcgagt tgccacatcc ggcccgcttg accaccaacc gcatcacacc
    18121 taagttaggt tcacttaaca catccagccc aagcgggccc gcggtcgtcg cgacatacgg
    18181 tcatgtttgg tcacgtaccg tcgccaacac ccatccgcag cgacccaccg caatcgcgat
    18241 ccttcacccc gacgggcgca acaaatcaac aacggatacc aaccacaagg tctccacaca
    18301 cactccgggt ggacccgacc gagcaccccc atcaccacct cgaccggcgc gacctcggcg
    18361 aacaccttga cagggcaaca ggtcgacccg aacataggta aagttaacct aaattcacat
    18421 ccggtcagat caaccgacaa gaggggcagc cgtgggagac cgtccaccga ccgcggaact
    18481 cggtgtgcac gacgtcatcg gagtcgggtt cggaccctcg aacatcgccc taggcatcgc
    18541 gatccaggaa cacaacagca gcgtctccgc cggggccgca ctgcgcgcga tctttcttga
    18601 acgccagccc cgcttcggtt ggcatcgcgg gatgctgctc gacggcgcca cgatgcaggt
    18661 gtccttcctc aaggatctgg cgacgctgcg aaatccgtcc agcagcttca gctttctgaa
    18721 ctacctgcat tcgcagaacc ggctcgtgga cttcatcaac cacaagacga tgttcccgct
    18781 gcgccacgaa taccacgact atctggaatg ggccgcgggc cggctcgact atctggtcga
    18841 atacgacacc gaggtcgtgg atctgcggcc ggtcgtccac gagggcgtgg tcgcctacat
    18901 cgacgtgatc agcggccggc ccggccagcc gggccgaacc gtcgtccgcc gggcccgcaa
    18961 cgtcgtcatc gccgccgggc tcgaaccgcg gctgccggaa aacgccgagc tcggcgaccg
    19021 cctgtggcac aaccacgacc tgctgcaccg gctcgcgcag atgccgtcga caccacgcca
    19081 gcgcttcgtc gtggtcgggg ccggccagag cgccgccgag gtgaccgaac acctgcacac
    19141 ccggttcccg caggccgagg tgttcgcggt cttcgcccgg tacgggctca caccggccga
    19201 caacagcggc ttcgtcaacc agatcttcga cccggacgcc gtcgacgagt tctaccacgc
    19261 gccggaaggc gtccgggaga tgctgctgac ctaccaccgc agcaccaact acgccgcggt
    19321 cgacatggac ctcatcgacg agctctaccg gcgcagctac caggagaagg tccgcgggcc
    19381 ccagcggctg tacttcctgc gagcctcgca ggtggaagcc tacgaggcgc tgccggacgg
    19441 cacccgggtc cacatccggc acctgcccac cggcgacaag cgggtcctgg acaccgacat
    19501 cgtcgtgctc gccaccggct acaacgcccg ggacccgcgg cgcgtgctcg gtagcatgga
    19561 ggacgcctgc ctggtcagcg actccggccg gctccaggtc gcacgcgact acagcatcga
    19621 gacgaagccc gacaccaccg ccggcatcta cgttcccggt gcgagcgagt tccagcacgg
    19681 catctcgtca tccctgctgt ccaacatctc gatccgggcc ggcgagatcc tcgactcggt
    19741 gctgcgtcga caggagctgg aagaaccact ggcggccatt ggccagggca tcacagcccc
    19801 ctcgtatctc cccgcccagc acaaggccca gccgcagaac tga
//
