BGC0002412: holomycin biosynthetic gene cluster from Photobacterium galatheae
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 78,725 - 91,151 nt. (total: 12,427 nt).
This entry is originally from NCBI GenBank JMIB01000043.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002412
Short description holomycin biosynthetic gene cluster from Photobacterium galatheae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
JMIB01000043.1
78725 - 91151
via Knock-out studies
Compounds
  • holomycin
Species Photobacterium galatheae [taxonomy]
References
Chemical products information
holomycin Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • EA58_20455
  • KDM89825.1
78725 - 79306 (-) flavoprotein
    copy AA seq
    copy Nt seq
    • EA58_20460
    • KDM89826.1
    79386 - 80210 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • EA58_20465
      • KDM89827.1
      80239 - 80772 (-) oxidoreductase
        copy AA seq
        copy Nt seq
        • EA58_20470
        • KDM89828.1
        80769 - 81647 (-) hypothetical protein
          copy AA seq
          copy Nt seq
          • EA58_20475
          • KDM89829.1
          81658 - 82794 (-) acyl-CoA dehydrogenase
            copy AA seq
            copy Nt seq
            • EA58_20480
            • KDM89830.1
            82791 - 83567 (-) oleoyl-ACP hydrolase
              copy AA seq
              copy Nt seq
              • EA58_20485
              • KDM89831.1
              83554 - 85200 (-) glucose-methanol-choline oxidoreductase
                copy AA seq
                copy Nt seq
                • EA58_20490
                • KDM89832.1
                85200 - 88589 (-) peptide synthetase
                  copy AA seq
                  copy Nt seq
                  • EA58_20495
                  • KDM89833.1
                  88840 - 90282 (-) MFS transporter permease
                    copy AA seq
                    copy Nt seq
                    • EA58_20500
                    • KDM89834.1
                    90489 - 91151 (-) ArsR family transcriptional regulator
                      copy AA seq
                      copy Nt seq
                      Biosynthesis information
                      Annotation changelog

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Detailed domain annotation
                      Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                      A domain glossary is available here, and an explanation of the visualisation is available here.
                      Selected features only
                      Show module domains
                      Similar known gene clusters from MIBiG 4.0
                      Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                      Click on reference genes to show details of similarities to genes within the current region.
                      Click on an accession to open that entry in the MiBIG database.