LOCUS       BGC0002424             19621 bp    DNA     linear   BCT 08-AUG-2021
DEFINITION  Saccharothrix sp. strain D09 saccharochelin biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0002424
VERSION     BGC0002424
KEYWORDS    .
SOURCE      Saccharothrix sp
  ORGANISM  Saccharothrix sp.
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharothrix.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:40:52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19621
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1749)
                     /gene="sacA"
     CDS             complement(1..1749)
                     /codon_start=1
                     /gene="sacA"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 274.6; E-value:
                     2.9e-83)"
                     /gene_kind="transport"
                     /product="putative ABC transporter"
                     /protein_id="QYI86758.1"
                     /transl_table=11
                     /translation="MPTGGVELMRELLATASGARTWAVVGELVRPRRAVAWAALLVLLA
                     GTAVGLLTAPVLGRIVDLVGAGSSAITWPVAVLALVAAVQGVSTAFGTSLVARLGEGML
                     ADLREKFVERALHLPLGRVEAAGSGDLTSRVTRDVQVIADAVRNALPVMARSALTIGLT
                     VVGIAVLDWRFLVPVLLAMPIHVHTVRWYGGRAVELYAAQRVAVGVQQQQLLDSIGGAA
                     TVRTFGLASAHVAQVRSRSRAAVDLALRGIRLLTRFYGRLNAAEFIGLAGVLVTGFWLV
                     GAGSASVGTATAAALYFHSLFNPVNAALALADDAQAATASLSRLVGVTDEPMPVLEGRV
                     RPADTTIKLAGVSYSYLDGHPVLRDVDLELAAGERVALVGASGAGKTTLAKLIAGVHEP
                     TTGSIHIGGVELGSAVRSVALITQEVHVFAGPLADDLRLARPDATDDELSAALARVGAL
                     DWASALPSGLDTVVGEGGHRLTVTQAQQLALARLVLADPPVAILDEATADAGSAGAREL
                     EEPAARALDGRTGLLVAHRLTQAMTADRVVVLEAGRVVESGPHEELLAAGGRYAELWAA
                     WSGTRA"
     source          1..19621
                     /db_xref="taxon:1873460"
                     /isolation_source="sediment collected from intertidal zone
                     of Fushan Bay, Qingdao, China, in October, 2014"
                     /mol_type="genomic DNA"
                     /organism="Saccharothrix sp."
                     /strain="D09"
     misc_feature    1..19621
                     /note="saccharochelin biosynthetic gene cluster"
     protocluster    1..19621
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6098:19430]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6099..19430
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..19621
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3591:19430]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      3592..19430
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
     cand_cluster    1..19621
                     /SMILES="NC(CCCN(O)C=O)C(=O)NC(CO)C(=O)NC(CCCNO)C(=O)NC(CCC
                     NO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..19621
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002424"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19621
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1778..3415)
                     /gene="sacB"
     CDS             complement(1778..3415)
                     /codon_start=1
                     /gene="sacB"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 617.2; E-value:
                     4.7e-187)"
                     /gene_kind="transport"
                     /product="putative ABC transporter"
                     /protein_id="QYI86759.1"
                     /transl_table=11
                     /translation="MTGQWRSVTVASALGAAHQAGEAAVPLLIGVVIDEAVRTGASGRL
                     VLWIGVLAAVFVTLSLSFRFSLRSGEKASHQAAHEVRSTLAARVLSADGGAARGRLSGE
                     LANIATSDAQRVGQVNLALPIAFSAVIGVLVGAVALLRVSWVLGVLVLVAAPVLLGLAH
                     VLGKPLERRSDAEQDRAALASGVAADLVAGLRALKGIGAEATAARRYRVTSRSSMAAAI
                     RAARSRAWLDGSMLAMTGVFLAVVALVGGHLAASGTITVGELVAAVGLAQFLLWPLSIF
                     AWVNGLLAQGRASAARVAEVLSAPPDVPPGSSHLPPTVAGRVELADVVSGSLRGVSFTA
                     SPGELLGVVARDPADAVSLLAVLAREVDPEDGTVALDGLPLSTVEGSALRAAVLVAAHD
                     ADLFEGSVRDNVAAGGTLVGEAMDAARVDDVARALPDGVDTVISARGRSLSGGQRQRVA
                     LARALAAAPPVLVVHDPTTAVDAVTEVSLAAGIKRMRAGLTTIVVATSPALLAAADRVV
                     FLASGVVVSSGAHADLVADEDYRLVVLS"
     gene            3592..4920
                     /gene="sacC"
     CDS             3592..4920
                     /codon_start=1
                     /gene="sacC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Orn_monoox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 554.1;
                     E-value: 3.1e-168)"
                     /gene_kind="biosynthetic"
                     /product="putative L-ornithine N5-oxygenase"
                     /protein_id="QYI86760.1"
                     /sec_met_domain="Orn_monoox (E-value: 3.4e-199, bitscore:
                     650.5, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPPVFDVLGVGFGPSNLALAIAVTEYNADARAEDVVTAHFLER
                     QPRFGWHRGMLIDDATMQVSFLKDLVTLRNPHSTFTFLSYLHSRGRLVDFINHKNLFPL
                     RVEFHDYFEWAAGRVDDLVSYDHDVVDVRPVTEDGVITHFDVVSRTSTGEVEVRRARNL
                     VLATGLRPALPEGVRPSARVWHNRDFLHRVESLADPRRLVVVGAGQSGAEVTAFLHERF
                     PAAEVCAVFARYGYSPADDSSFANRIFDPAAVDDYFAAPEQVKRKLMDYHGNTNYAVVD
                     NELIAELYRRVYREKVVGRQRLRLLNLSRVAELDDREDGVAVTVESLSTGAREVLDADA
                     IVYATGYREADPTGLLGELAGRCARDAHDRLSVGRDYRLDTDDDLSAGLYLQGGTEHTH
                     GISSSLLSNTSVRVGEILQSVLGRRVPVAPVQPEYAISVSRVG"
     gene            5000..6010
                     /gene="sacD"
     CDS             5000..6010
                     /codon_start=1
                     /gene="sacD"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 261; E-value:
                     1.9e-79)"
                     /gene_kind="transport"
                     /product="putative ABC transporter"
                     /protein_id="QYI86761.1"
                     /transl_table=11
                     /translation="MMSTKFKLVAAVSVAALALAACGGGGDAGTGGTSENAAATGAFPV
                     SVEHEYGTTEIKAEPKKVVTLGLSDQEPVLALGVKPVGVVDWFKERPYGNWPWTKELWG
                     DTQPEVVGERDEYNLEKVAALKPDLILAVYSGMKQEQYDTLSKIAPVVAQPKAFPDYAA
                     PWQDQTLHIGKALGKEEEAQALIDGVAKRFADAKAAHPEWAGKTMVVADSFKPGQYSAF
                     APTDPKAIFMKELGFTLVDEIGKLAGQLNVAEFSEERFDLLDADRLVWLMFDQSAWERV
                     KSVPAYQRLEVVSEKRDLFLTYMDPPIGAAMSFNTVLSVPYGIDQVVPLLEAIKN"
     gene            6099..19430
                     /gene="sacE"
     CDS             6099..19430
                     /NRPS_PKS="Domain: Condensation_Starter (1-266). E-value:
                     6.1e-71. Score: 231.0. Matches aSDomain:
                     nrpspksdomains_sacE_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (423-797). E-value: 1.2e-98.
                     Score: 322.3. Matches aSDomain:
                     nrpspksdomains_sacE_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (901-966). E-value: 9.2e-20. Score:
                     62.5. Matches aSDomain: nrpspksdomains_sacE_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (980-1277). E-value:
                     7.3e-40. Score: 128.8. Matches aSDomain:
                     nrpspksdomains_sacE_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1423-1798). E-value:
                     5.3e-103. Score: 336.6. Matches aSDomain:
                     nrpspksdomains_sacE_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1896-1960). E-value: 1.9e-20.
                     Score: 64.7. Matches aSDomain: nrpspksdomains_sacE_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1986-2274). E-value:
                     4.6e-97. Score: 316.6. Matches aSDomain:
                     nrpspksdomains_sacE_Condensation_DCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2434-2836). E-value:
                     5.5e-93. Score: 303.6. Matches aSDomain:
                     nrpspksdomains_sacE_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2939-3005). E-value: 8.3e-30.
                     Score: 94.7. Matches aSDomain: nrpspksdomains_sacE_PCP.3"
                     /NRPS_PKS="Domain: Condensation_LCL (3020-3313). E-value:
                     3e-107. Score: 349.9. Matches aSDomain:
                     nrpspksdomains_sacE_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3478-3871). E-value: 4e-99.
                     Score: 323.8. Matches aSDomain:
                     nrpspksdomains_sacE_AMP-binding.4"
                     /NRPS_PKS="Domain: PCP (3974-4039). E-value: 6.4e-22.
                     Score: 69.4. Matches aSDomain: nrpspksdomains_sacE_PCP.4"
                     /NRPS_PKS="Domain: Condensation_LCL (4070-4324). E-value:
                     3.2e-58. Score: 189.0. Matches aSDomain:
                     nrpspksdomains_sacE_Condensation_LCL.2"
                     /codon_start=1
                     /gene="sacE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 20.4; E-value: 7.5e-06)"
                     /gene_kind="biosynthetic"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="QYI86762.1"
                     /sec_met_domain="PP-binding (E-value: 9.8e-19, bitscore:
                     56.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.5e-68, bitscore:
                     218.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-111, bitscore:
                     359.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPLTGAQTGVWLAQQLEPDNPVYNVAWYLELRGPVDHDRLAAA
                     VRQTIGETGALHVRFTGDGQVPTPPTTDLTLLSFDSLADARAWMDDDMARLTDIATGPL
                     FHHALLRIADDHVLWYQRYHHLVVDAYGCVLITRRAGELYEGATEPRPKPVQALVDADL
                     AYRDSPDRDADRAFWHAKMADRPEPVRLVPRAAGQVREVIRRTVELPNPLTSRQVIAAV
                     ATYTHRVTGASDLVLAMPVTGRRDAVSRVTPGMASTVLPLRVTVRPDSTITGLIADVDR
                     EIREVVPRSAYRGEDLARELGLRDGIPELVGPTVNYLGFGREMGFADLDPAFHMLSLGP
                     VNDLTTSFLRRADGRLVVTFEANAAVCTPAELADHQRRFLRVLAADPDQPVALIDLVDD
                     AERARLLDFGTSPREVDEVTWPGAFERQAALRPDAVAVVCEDVTLTYAELNVAANRLAR
                     ALVASGVRAEDVVGVALPRSADLVVTLLAVMKAGAAYLPLDLDHPRDRVDHMVADAGAT
                     LVITPETRFELPDDGSDLGLDIALDQAAYVIYTSGSTGRPKGVVVTHEGIGSLVATALD
                     RIGITPDSRVVQFASVGFDVAVWDLCMSLGVGGRAVLVPSHRRVAGEELTSYIAEHRAT
                     HMILPPSLVAALPPECELPAGAVLIVGTETVPTELIARWARRLRVVAAYGLTEATVNST
                     LWAARPDWTGPVPIGVPDPNTRCYVLDSALRPVPVGVEGELYVGGRGLARGYRGQAALT
                     ASRFVADPFAGPGSRMYRTGDRARWRADGNLDFLGRSDGQVKIRGFRIEPGEVESVLMA
                     HPAVAQAAVLVREDHRRVKRLVAYVVGTASPVDAREHVASALPDYMVPSVVVPLPGPLP
                     LTPNGKLDRAALPEPDWTAPAGDAPATNPVEQTLVALVEAVLGVTPGIHDNFFELGGDS
                     IVTVQLVSRAREAGLEFTPREVFEHRTVAGLARVARAVSGVDVSLDGFSSDVLPASPLQ
                     EGFFFHARYDTDDSYVVQEVLSLAVDRDAVQGLLDRHPLLRAGFRQTDRGRVEQVIAEA
                     LTLPWRDYPATDDVEAVLAAERAEPFDLSRPPLMRAARHGDRLVLTLHHILLDGWSVGL
                     LRRELVGGRLAPVDHRRYFAWLASRDRAAAHEAWRAALSDVDEPTRIAGLSTTSPVRPG
                     IVGASRQNHSRGPLGGDVREALPLAEVSPRHGQHRVRLAAELSAALVGEARRRGLTLST
                     VLHGAWGLLLGGLTGRADVVYGTTVAGRPAEVPGIENAVGLFINTVPVRQRWRGDDSLA
                     TTFQRLQGEQARLLDHQHLGLAEIQRVTGHGELFDTLVVVENFPDVVDDVEIRDQVHYP
                     LALIALPGERLELRLKHRLPDAEVASLAQRLVRLLTAFATTPDRPVASLDLLSDTETEW
                     LARLNATTADVPEGTLVSRIAAQTARTPDAVAVVYENITLTYAELDRRATALARTLHGH
                     RVVGVAVPRSAELLVALLAVLKSGAAYLPLDLDYPAERVEFMLADSGATAVIRPEDCVD
                     TGTPPVDLPAPHPDQPAYLIYTSGSTGRPKGVVVTHRAIVNRLAWMQHEYGLTADDRVL
                     QKTPSSFDVSVWEFFWALCEGAAVVLAKPDGHRDPAYLADLICRERITTLHFVPSMLAA
                     FLGVPEAHDDKSWSTSLRRAFSSGEALTGDVAGRWLELTAVPLHNLYGPTEAAVDVTYF
                     EYDAAPDPAVPIGRPVWNTRLHVLDPFLRPVPANVPGELYLAGVQLALGYHGRFALTAE
                     RFVADPFGAPGERMYRTGDLVVRRPDGVLVYLGRTDRQVKVRGNRIELGEVESALVKQP
                     GVRRAAVIARGDQLLGYVTPADVDLDAVRSGVAAALPAAMVPHAVVALPDFPLTPSGKL
                     DQDALPSPTLAKTGRRAPATDRERLLGEVFADVLGLADLGVDDDFFVLGGDSITSIAVS
                     SRARGLGIGISPRDVFEHRTVAALAAVETTADTAADAPLLVLTEDQRAALPEAEDVWPL
                     SPLQEGLYFHASYDTGALDVYLSQETMDFAGRLDVDRLRRAGAALLARNPSLRAGFTSD
                     GVPAPVQFIAPGLEIPLRVVEADDTEAPELLAADRRERFDLAAPPLCRFLVLRLPDGRD
                     RLVITHHLILWDGWSAWLFLEQLLELYRDVDAELPPPGTYRDYLAWLARQDHDAALRAW
                     RTALSGLREPTLVAPVDRSREPVIPAEFHQELSEELTDRVRARARQHGLTANAVFNTAW
                     AMVLASQVGRDDVVFGTAVAGRPVEVDGVEHVIGMFLNTIPTRIALDPRETVLELLRRV
                     QAERTALMSYEHVGLGEIQREAGHRQLFDTLFVLRTGDGDDRQGEFASRHGVLEVSNVD
                     GTHFPLTLIITPGARTRVTLASRPDVFAADAAEALLTRYTTVLRRLVDAPDALIGTLDV
                     LPDHERRTLVAEWDAGANPMISETVADLLAAQALRTPDATALVFGDQRLTYAELQDRID
                     TLARLLISRGAGPERVVALALPRTTEMVVALFAVLRTGAAYLPLDLDHPADRLLLMIED
                     TKPLCVLSTTAVGLVPDALCVDDLPAGPDHVEWPTFSLDHPAYVIYTSGSTGRPKGVVT
                     PYRGLTNMQLNHQQAIFAPAIAAAGGRRLRIAHTVSFAFDMSWEELLWLVEGHEVHVCD
                     EELRRDAAALVAYCDEHLVDVVNVTPTYAQLLIEEGLLEGHVPALVLLGGEAVPESVWQ
                     RLRETPGTYGYNLYGPTEYTINTLGASTEDSATATVGKAIWNTRAYVLDAHLRPVPPGS
                     PGELYIAGVGLARGYHDRFGLTAERFVADPYGPPGTRMYRTGDLVRARAVSSLDPASRS
                     SAGNLDFLGRTDDQVKIRGYRVEPGEVESALAGQPGVTHAAVVVDAGPGGVKRLVGYVV
                     SSVDPVVLRDRLKTSLPDYMVPAAIMPVDALPLTVNGKLDVRALPKPVVTGAASSRAAA
                     TRAEEVLCGLFADVLGVPAVGADDNFFDLGGHSLLATRLISRARSALGVELAIRDLFDA
                     PTVAELASRAGGGSARPPLVAGQRPAELPLSSAQQRLWLIQQMEGTSAAYNFPLVFTLH
                     GSLDVAAFTAAVGDVVDRHEALRTVFGEHEGTPFQRVLHDVAPVVVVRSAGGHEVPDIV
                     RAEVERPFDLRAELPLRVTVASLAPEEHLVVILLHHITTDEWSDRPFLRDLATAYRARR
                     DGDVPLWTPLPVQYADYTVWQRDVLEIVGEQQSDFWARTLAGAPEELELPVDRPRPGRP
                     TFRGADLEVVFEPASADALRAFAQTSGASMFMVLQAAVAALLGRLGAGDDIPLGAPIAG
                     RTDEALDDLVGFFVNTLVLRADLSGDPSFAEVVARVKETSLAAFSHQDVPFEAVVDRIN
                     PTRSAARNPLFQVMVGYHSRGGDSGTFDGLPVTWVGHETTTAKFDLVFSFTDVVDGPVV
                     CRLEYATDLFDRVTVQRLGARLTTLVDAVLAAPSAPVSAVDLLAPDERRRVVDEFNRTA
                     RAVPEETFTTMFARCVAARPDAVAVVDRHRSVDYAWLDDRSDRIARLLAARGVGHESVV
                     GIAVPKSADMVATVVATLKLGAAYLPLDLSHPADRVAYMIQDSGATLVVTTRAAPVPDV
                     AEILLLDSDAVRDELSAESEAAPATGPRSLDSAMYVIYTSGSTGRPKGVVVPHEGIASL
                     AATAIDRMGLTAESRVLQFASVGFDVAVFELTMALCVGGRLVFAPDEVRVAGPELTDFL
                     RDRRITHMILPPSLVSALPADCELPEGSTILVGTETVPPDVIGRWAGRLTLLAAYGLTE
                     ATVNSTLWKAVPEWDSAVPIGIPDPNTTVYVLDDRLRPVPPGVVGELYVSGRGLARGYI
                     GQSALTASRFVASPFGPPGARMYRTGDRARWRADGNLDFLGRVDTQVKIRGFRIELGEI
                     EAALTRHPDVAQAAVIADRTGDVTRLVAYVVGSTGDDLRALVAERLPEYMVPATVIFLA
                     GPLPLTPNGKLDRRALPTPDWSALTGDDRPVTPEQKAIAELFAELLGVSPGIHDNFFTL
                     GGHSMASMRLVGKIRSVFGVDIALRDVFDSPTVAGLAGRLTGATSARPPLRRFDRPVDL
                     PLAPVQRGPVSWDHALALRATTPFDVPALVDAYADVVGRHEPLRTVLDGGVQRAVPVPP
                     LEVEPVVALDEALPAFAAEPVEPGRPPVRARLVVDASGAQALLLTMSYLAVDEWSVVPL
                     FRDLQHAYAARRRGEAPQWTELPVTYADYALWSREVVESVGERQHAFWRDALRDLPDLA
                     LPYVGDRRPGRHPAAVIPFELPASLHAAIDRLATRTGTSMFMVVQAAVAAALTPYGTDL
                     PIGTMVAGRTEEALADLVGCFFNRVVLRTDTAGQPGYTELLARVRATDLAAFDHADVPV
                     PVEPQVMIVHHEKAVLSTLEGGAGSLEAVPTGTTPAELTVSFYEPRDDGPVPCYLVYAT
                     DLFTDATAHHLADAVLRHLHRATTDPDRRIQP"
     aSDomain        6102..6896
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="6.10E-71"
                     /label="sacE_Condensation_Starter.1"
                     /locus_tag="sacE"
                     /protein_end="266"
                     /protein_start="1"
                     /score="231.0"
                     /tool="antismash"
                     /translation="ALPLTGAQTGVWLAQQLEPDNPVYNVAWYLELRGPVDHDRLAAAV
                     RQTIGETGALHVRFTGDGQVPTPPTTDLTLLSFDSLADARAWMDDDMARLTDIATGPLF
                     HHALLRIADDHVLWYQRYHHLVVDAYGCVLITRRAGELYEGATEPRPKPVQALVDADLA
                     YRDSPDRDADRAFWHAKMADRPEPVRLVPRAAGQVREVIRRTVELPNPLTSRQVIAAVA
                     TYTHRVTGASDLVLAMPVTGRRDAVSRVTPGMASTVLPLRVTV"
     aSModule        6102..8996
                     /complete
                     /domains="nrpspksdomains_sacE_Condensation_Starter.1"
                     /domains="nrpspksdomains_sacE_AMP-binding.1"
                     /domains="nrpspksdomains_sacE_PCP.1"
                     /locus_tags="sacE"
                     /monomer_pairings="Fo-OH-Orn -> Fo-OH-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6105..6146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0001"
                     /evalue="7.30E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="sacE"
                     /protein_end="16"
                     /protein_start="2"
                     /score="9.4"
                     /tool="antismash"
                     /translation="LPLTGAQTGVWLAQ"
     CDS_motif       6165..6281
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0002"
                     /evalue="1.40E-16"
                     /label="C2_starter_024-063"
                     /locus_tag="sacE"
                     /protein_end="61"
                     /protein_start="22"
                     /score="53.0"
                     /tool="antismash"
                     /translation="PVYNVAWYLELRGPVDHDRLAAAVRQTIGETGALHVRFT"
     CDS_motif       6465..6530
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0003"
                     /evalue="3.50E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="sacE"
                     /protein_end="144"
                     /protein_start="122"
                     /score="23.1"
                     /tool="antismash"
                     /translation="YHHLVVDAYGCVLITRRAGELY"
     CDS_motif       6798..6887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0004"
                     /evalue="9.10E-10"
                     /label="C5_starter_265-294"
                     /locus_tag="sacE"
                     /protein_end="263"
                     /protein_start="233"
                     /score="30.9"
                     /tool="antismash"
                     /translation="DLVLAMPVTGRRDAVSRVTPGMASTVLPLR"
     CDS_motif       6939..7049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0005"
                     /evalue="2.20E-06"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="sacE"
                     /protein_end="317"
                     /protein_start="280"
                     /score="20.3"
                     /tool="antismash"
                     /translation="REIREVVPRSAYRGEDLARELGLRDGIPELVGPTVNY"
     aSDomain        7368..8489
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_AMP-binding.1"
                     /evalue="1.20E-98"
                     /label="sacE_AMP-binding.1"
                     /locus_tag="sacE"
                     /protein_end="797"
                     /protein_start="423"
                     /score="322.3"
                     /specificity="substrate consensus: Fo-OH-Orn"
                     /tool="antismash"
                     /translation="FERQAALRPDAVAVVCEDVTLTYAELNVAANRLARALVASGVRAE
                     DVVGVALPRSADLVVTLLAVMKAGAAYLPLDLDHPRDRVDHMVADAGATLVITPETRFE
                     LPDDGSDLGLDIALDQAAYVIYTSGSTGRPKGVVVTHEGIGSLVATALDRIGITPDSRV
                     VQFASVGFDVAVWDLCMSLGVGGRAVLVPSHRRVAGEELTSYIAEHRATHMILPPSLVA
                     ALPPECELPAGAVLIVGTETVPTELIARWARRLRVVAAYGLTEATVNSTLWAARPDWTG
                     PVPIGVPDPNTRCYVLDSALRPVPVGVEGELYVGGRGLARGYRGQAALTASRFVADPFA
                     GPGSRMYRTGDRARWRADGNLDFLGRSDGQVKIR"
     CDS_motif       7554..7595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0006"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sacE"
                     /protein_end="499"
                     /protein_start="485"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LAVMKAGAAYLPLD"
     CDS_motif       7731..7790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0007"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="sacE"
                     /protein_end="564"
                     /protein_start="544"
                     /score="32.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVVTH"
     CDS_motif       8148..8174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0008"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="sacE"
                     /protein_end="692"
                     /protein_start="683"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGLTEATVN"
     CDS_motif       8280..8369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0009"
                     /evalue="8.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="sacE"
                     /protein_end="757"
                     /protein_start="727"
                     /score="43.6"
                     /tool="antismash"
                     /translation="PVGVEGELYVGGRGLARGYRGQAALTASRF"
     CDS_motif       8454..8519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0010"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sacE"
                     /protein_end="807"
                     /protein_start="785"
                     /score="35.4"
                     /tool="antismash"
                     /translation="FLGRSDGQVKIRGFRIEPGEVE"
     CDS_motif       8724..8750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0011"
                     /evalue="1.60E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="sacE"
                     /protein_end="884"
                     /protein_start="875"
                     /score="2.5"
                     /tool="antismash"
                     /translation="GKLDRAALP"
     aSDomain        8802..8996
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_PCP.1"
                     /evalue="9.20E-20"
                     /label="sacE_PCP.1"
                     /locus_tag="sacE"
                     /protein_end="966"
                     /protein_start="901"
                     /score="62.5"
                     /tool="antismash"
                     /translation="EQTLVALVEAVLGVTPGIHDNFFELGGDSIVTVQLVSRAREAGLE
                     FTPREVFEHRTVAGLARVAR"
     CDS_motif       8862..8891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0012"
                     /evalue="2.70E-01"
                     /label="PCP_mE"
                     /locus_tag="sacE"
                     /protein_end="931"
                     /protein_start="921"
                     /score="4.8"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        9039..9929
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.30E-40"
                     /label="sacE_Condensation_DCL.1"
                     /locus_tag="sacE"
                     /protein_end="1277"
                     /protein_start="980"
                     /score="128.8"
                     /tool="antismash"
                     /translation="DVLPASPLQEGFFFHARYDTDDSYVVQEVLSLAVDRDAVQGLLDR
                     HPLLRAGFRQTDRGRVEQVIAEALTLPWRDYPATDDVEAVLAAERAEPFDLSRPPLMRA
                     ARHGDRLVLTLHHILLDGWSVGLLRRELVGGRLAPVDHRRYFAWLASRDRAAAHEAWRA
                     ALSDVDEPTRIAGLSTTSPVRPGIVGASRQNHSRGPLGGDVREALPLAEVSPRHGQHRV
                     RLAAELSAALVGEARRRGLTLSTVLHGAWGLLLGGLTGRADVVYGTTVAGRPAEVPGIE
                     NAVGLFINTVPVRQRW"
     aSModule        9039..11978
                     /complete
                     /domains="nrpspksdomains_sacE_Condensation_DCL.1"
                     /domains="nrpspksdomains_sacE_AMP-binding.2"
                     /domains="nrpspksdomains_sacE_PCP.2"
                     /locus_tags="sacE"
                     /monomer_pairings="Ser -> Ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9048..9086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0013"
                     /evalue="1.40E-01"
                     /label="C1_DCL_004-017"
                     /locus_tag="sacE"
                     /protein_end="996"
                     /protein_start="983"
                     /score="5.5"
                     /tool="antismash"
                     /translation="PASPLQEGFFFHA"
     CDS_motif       9381..9437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0014"
                     /evalue="7.10E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="sacE"
                     /protein_end="1113"
                     /protein_start="1094"
                     /score="25.0"
                     /tool="antismash"
                     /translation="LHHILLDGWSVGLLRRELV"
     CDS_motif       9462..9497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0015"
                     /evalue="8.90E+00"
                     /label="C4_DCL_171-183"
                     /locus_tag="sacE"
                     /protein_end="1133"
                     /protein_start="1121"
                     /score="0.7"
                     /tool="antismash"
                     /translation="HRRYFAWLASRD"
     CDS_motif       9825..9920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0016"
                     /evalue="9.00E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="sacE"
                     /protein_end="1274"
                     /protein_start="1242"
                     /score="59.9"
                     /tool="antismash"
                     /translation="DVVYGTTVAGRPAEVPGIENAVGLFINTVPVR"
     CDS_motif       9969..10082
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0017"
                     /evalue="3.30E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="sacE"
                     /protein_end="1328"
                     /protein_start="1290"
                     /score="61.3"
                     /tool="antismash"
                     /translation="QGEQARLLDHQHLGLAEIQRVTGHGELFDTLVVVENFP"
     aSDomain        10368..11492
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_AMP-binding.2"
                     /evalue="5.30E-103"
                     /label="sacE_AMP-binding.2"
                     /locus_tag="sacE"
                     /protein_end="1798"
                     /protein_start="1423"
                     /score="336.6"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="AQTARTPDAVAVVYENITLTYAELDRRATALARTLHGHRVVGVAV
                     PRSAELLVALLAVLKSGAAYLPLDLDYPAERVEFMLADSGATAVIRPEDCVDTGTPPVD
                     LPAPHPDQPAYLIYTSGSTGRPKGVVVTHRAIVNRLAWMQHEYGLTADDRVLQKTPSSF
                     DVSVWEFFWALCEGAAVVLAKPDGHRDPAYLADLICRERITTLHFVPSMLAAFLGVPEA
                     HDDKSWSTSLRRAFSSGEALTGDVAGRWLELTAVPLHNLYGPTEAAVDVTYFEYDAAPD
                     PAVPIGRPVWNTRLHVLDPFLRPVPANVPGELYLAGVQLALGYHGRFALTAERFVADPF
                     GAPGERMYRTGDLVVRRPDGVLVYLGRTDRQVKVR"
     CDS_motif       10533..10574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0018"
                     /evalue="7.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sacE"
                     /protein_end="1492"
                     /protein_start="1478"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LAVLKSGAAYLPLD"
     CDS_motif       10707..10766
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0019"
                     /evalue="3.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="sacE"
                     /protein_end="1556"
                     /protein_start="1536"
                     /score="31.7"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGRPKGVVVTH"
     CDS_motif       11151..11174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0020"
                     /evalue="9.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="sacE"
                     /protein_end="1692"
                     /protein_start="1684"
                     /score="3.2"
                     /tool="antismash"
                     /translation="YGPTEAAV"
     CDS_motif       11283..11372
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0021"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="sacE"
                     /protein_end="1758"
                     /protein_start="1728"
                     /score="40.0"
                     /tool="antismash"
                     /translation="PANVPGELYLAGVQLALGYHGRFALTAERF"
     CDS_motif       11457..11522
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0022"
                     /evalue="1.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="sacE"
                     /protein_end="1808"
                     /protein_start="1786"
                     /score="32.8"
                     /tool="antismash"
                     /translation="YLGRTDRQVKVRGNRIELGEVE"
     CDS_motif       11712..11738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0023"
                     /evalue="2.30E+01"
                     /label="NRPS-A_a10"
                     /locus_tag="sacE"
                     /protein_end="1880"
                     /protein_start="1871"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="GKLDQDALP"
     aSDomain        11787..11978
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_PCP.2"
                     /evalue="1.90E-20"
                     /label="sacE_PCP.2"
                     /locus_tag="sacE"
                     /protein_end="1960"
                     /protein_start="1896"
                     /score="64.7"
                     /tool="antismash"
                     /translation="ERLLGEVFADVLGLADLGVDDDFFVLGGDSITSIAVSSRARGLGI
                     GISPRDVFEHRTVAALAAV"
     CDS_motif       11850..11879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0024"
                     /evalue="1.60E+00"
                     /label="PCP_mE"
                     /locus_tag="sacE"
                     /protein_end="1927"
                     /protein_start="1917"
                     /score="2.8"
                     /tool="antismash"
                     /translation="DFFVLGGDSI"
     aSDomain        12057..12920
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_Condensation_DCL.2"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.60E-97"
                     /label="sacE_Condensation_DCL.2"
                     /locus_tag="sacE"
                     /protein_end="2274"
                     /protein_start="1986"
                     /score="316.6"
                     /tool="antismash"
                     /translation="EDVWPLSPLQEGLYFHASYDTGALDVYLSQETMDFAGRLDVDRLR
                     RAGAALLARNPSLRAGFTSDGVPAPVQFIAPGLEIPLRVVEADDTEAPELLAADRRERF
                     DLAAPPLCRFLVLRLPDGRDRLVITHHLILWDGWSAWLFLEQLLELYRDVDAELPPPGT
                     YRDYLAWLARQDHDAALRAWRTALSGLREPTLVAPVDRSREPVIPAEFHQELSEELTDR
                     VRARARQHGLTANAVFNTAWAMVLASQVGRDDVVFGTAVAGRPVEVDGVEHVIGMFLNT
                     IPTRIAL"
     aSModule        12057..15113
                     /complete
                     /domains="nrpspksdomains_sacE_Condensation_DCL.2"
                     /domains="nrpspksdomains_sacE_AMP-binding.3"
                     /domains="nrpspksdomains_sacE_PCP.3"
                     /locus_tags="sacE"
                     /monomer_pairings="OH-Orn -> OH-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12066..12107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0025"
                     /evalue="5.10E-03"
                     /label="C1_DCL_004-017"
                     /locus_tag="sacE"
                     /protein_end="2003"
                     /protein_start="1989"
                     /score="9.5"
                     /tool="antismash"
                     /translation="WPLSPLQEGLYFHA"
     CDS_motif       12129..12242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0026"
                     /evalue="5.30E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="sacE"
                     /protein_end="2048"
                     /protein_start="2010"
                     /score="31.6"
                     /tool="antismash"
                     /translation="DVYLSQETMDFAGRLDVDRLRRAGAALLARNPSLRAGF"
     CDS_motif       12453..12509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0027"
                     /evalue="2.50E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="sacE"
                     /protein_end="2137"
                     /protein_start="2118"
                     /score="13.8"
                     /tool="antismash"
                     /translation="ILWDGWSAWLFLEQLLELY"
     CDS_motif       12546..12581
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0028"
                     /evalue="1.80E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="sacE"
                     /protein_end="2161"
                     /protein_start="2149"
                     /score="8.2"
                     /tool="antismash"
                     /translation="YRDYLAWLARQD"
     CDS_motif       12816..12911
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0029"
                     /evalue="2.40E-15"
                     /label="C5_DCL_263-294"
                     /locus_tag="sacE"
                     /protein_end="2271"
                     /protein_start="2239"
                     /score="48.9"
                     /tool="antismash"
                     /translation="DVVFGTAVAGRPVEVDGVEHVIGMFLNTIPTR"
     CDS_motif       12960..13058
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0030"
                     /evalue="1.60E-09"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="sacE"
                     /protein_end="2320"
                     /protein_start="2287"
                     /score="30.1"
                     /tool="antismash"
                     /translation="QAERTALMSYEHVGLGEIQREAGHRQLFDTLFV"
     aSDomain        13401..14606
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_AMP-binding.3"
                     /evalue="5.50E-93"
                     /label="sacE_AMP-binding.3"
                     /locus_tag="sacE"
                     /protein_end="2836"
                     /protein_start="2434"
                     /score="303.6"
                     /specificity="substrate consensus: OH-Orn"
                     /tool="antismash"
                     /translation="AAQALRTPDATALVFGDQRLTYAELQDRIDTLARLLISRGAGPER
                     VVALALPRTTEMVVALFAVLRTGAAYLPLDLDHPADRLLLMIEDTKPLCVLSTTAVGLV
                     PDALCVDDLPAGPDHVEWPTFSLDHPAYVIYTSGSTGRPKGVVTPYRGLTNMQLNHQQA
                     IFAPAIAAAGGRRLRIAHTVSFAFDMSWEELLWLVEGHEVHVCDEELRRDAAALVAYCD
                     EHLVDVVNVTPTYAQLLIEEGLLEGHVPALVLLGGEAVPESVWQRLRETPGTYGYNLYG
                     PTEYTINTLGASTEDSATATVGKAIWNTRAYVLDAHLRPVPPGSPGELYIAGVGLARGY
                     HDRFGLTAERFVADPYGPPGTRMYRTGDLVRARAVSSLDPASRSSAGNLDFLGRTDDQV
                     KIR"
     CDS_motif       13584..13625
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0031"
                     /evalue="9.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="sacE"
                     /protein_end="2509"
                     /protein_start="2495"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FAVLRTGAAYLPLD"
     CDS_motif       13791..13844
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0032"
                     /evalue="1.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="sacE"
                     /protein_end="2582"
                     /protein_start="2564"
                     /score="26.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVVT"
     CDS_motif       14238..14267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0033"
                     /evalue="4.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="sacE"
                     /protein_end="2723"
                     /protein_start="2713"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPTEYTINT"
     CDS_motif       14364..14453
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0034"
                     /evalue="1.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="sacE"
                     /protein_end="2785"
                     /protein_start="2755"
                     /score="46.5"
                     /tool="antismash"
                     /translation="PPGSPGELYIAGVGLARGYHDRFGLTAERF"
     CDS_motif       14571..14636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0035"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="sacE"
                     /protein_end="2846"
                     /protein_start="2824"
                     /score="36.8"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRVEPGEVE"
     CDS_motif       14838..14864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0036"
                     /evalue="2.90E+01"
                     /label="NRPS-A_a10"
                     /locus_tag="sacE"
                     /protein_end="2922"
                     /protein_start="2913"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="GKLDVRALP"
     aSDomain        14916..15113
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_PCP.3"
                     /evalue="8.30E-30"
                     /label="sacE_PCP.3"
                     /locus_tag="sacE"
                     /protein_end="3005"
                     /protein_start="2939"
                     /score="94.7"
                     /tool="antismash"
                     /translation="EEVLCGLFADVLGVPAVGADDNFFDLGGHSLLATRLISRARSALG
                     VELAIRDLFDAPTVAELASRA"
     CDS_motif       14979..15008
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0037"
                     /evalue="2.80E+01"
                     /label="PCP_mE"
                     /locus_tag="sacE"
                     /protein_end="2970"
                     /protein_start="2960"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="NFFDLGGHSL"
     aSDomain        15159..16037
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.00E-107"
                     /label="sacE_Condensation_LCL.1"
                     /locus_tag="sacE"
                     /protein_end="3313"
                     /protein_start="3020"
                     /score="349.9"
                     /tool="antismash"
                     /translation="AELPLSSAQQRLWLIQQMEGTSAAYNFPLVFTLHGSLDVAAFTAA
                     VGDVVDRHEALRTVFGEHEGTPFQRVLHDVAPVVVVRSAGGHEVPDIVRAEVERPFDLR
                     AELPLRVTVASLAPEEHLVVILLHHITTDEWSDRPFLRDLATAYRARRDGDVPLWTPLP
                     VQYADYTVWQRDVLEIVGEQQSDFWARTLAGAPEELELPVDRPRPGRPTFRGADLEVVF
                     EPASADALRAFAQTSGASMFMVLQAAVAALLGRLGAGDDIPLGAPIAGRTDEALDDLVG
                     FFVNTLVLRADL"
     aSModule        15159..18215
                     /complete
                     /domains="nrpspksdomains_sacE_Condensation_LCL.1"
                     /domains="nrpspksdomains_sacE_AMP-binding.4"
                     /domains="nrpspksdomains_sacE_PCP.4"
                     /locus_tags="sacE"
                     /monomer_pairings="OH-Orn -> OH-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       15165..15206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0038"
                     /evalue="6.40E-02"
                     /label="C1_starter_004-017"
                     /locus_tag="sacE"
                     /protein_end="3036"
                     /protein_start="3022"
                     /score="6.6"
                     /tool="antismash"
                     /translation="LPLSSAQQRLWLIQ"
     CDS_motif       15225..15338
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0039"
                     /evalue="1.90E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="sacE"
                     /protein_end="3080"
                     /protein_start="3042"
                     /score="55.6"
                     /tool="antismash"
                     /translation="AAYNFPLVFTLHGSLDVAAFTAAVGDVVDRHEALRTVF"
     CDS_motif       15537..15602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0040"
                     /evalue="2.70E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="sacE"
                     /protein_end="3168"
                     /protein_start="3146"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LHHITTDEWSDRPFLRDLATAY"
     CDS_motif       15651..15689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0041"
                     /evalue="1.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="sacE"
                     /protein_end="3197"
                     /protein_start="3184"
                     /score="14.7"
                     /tool="antismash"
                     /translation="QYADYTVWQRDVL"
     CDS_motif       15939..16028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0042"
                     /evalue="9.20E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="sacE"
                     /protein_end="3310"
                     /protein_start="3280"
                     /score="43.8"
                     /tool="antismash"
                     /translation="DIPLGAPIAGRTDEALDDLVGFFVNTLVLR"
     CDS_motif       16077..16196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0043"
                     /evalue="5.20E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="sacE"
                     /protein_end="3366"
                     /protein_start="3326"
                     /score="63.8"
                     /tool="antismash"
                     /translation="KETSLAAFSHQDVPFEAVVDRINPTRSAARNPLFQVMVGY"
     aSDomain        16533..17711
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_AMP-binding.4"
                     /evalue="4.00E-99"
                     /label="sacE_AMP-binding.4"
                     /locus_tag="sacE"
                     /protein_end="3871"
                     /protein_start="3478"
                     /score="323.8"
                     /specificity="substrate consensus: OH-Orn"
                     /tool="antismash"
                     /translation="FARCVAARPDAVAVVDRHRSVDYAWLDDRSDRIARLLAARGVGHE
                     SVVGIAVPKSADMVATVVATLKLGAAYLPLDLSHPADRVAYMIQDSGATLVVTTRAAPV
                     PDVAEILLLDSDAVRDELSAESEAAPATGPRSLDSAMYVIYTSGSTGRPKGVVVPHEGI
                     ASLAATAIDRMGLTAESRVLQFASVGFDVAVFELTMALCVGGRLVFAPDEVRVAGPELT
                     DFLRDRRITHMILPPSLVSALPADCELPEGSTILVGTETVPPDVIGRWAGRLTLLAAYG
                     LTEATVNSTLWKAVPEWDSAVPIGIPDPNTTVYVLDDRLRPVPPGVVGELYVSGRGLAR
                     GYIGQSALTASRFVASPFGPPGARMYRTGDRARWRADGNLDFLGRVDTQVKIR"
     CDS_motif       16722..16760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0044"
                     /evalue="4.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="sacE"
                     /protein_end="3554"
                     /protein_start="3541"
                     /score="10.6"
                     /tool="antismash"
                     /translation="ATLKLGAAYLPLD"
     CDS_motif       16953..17012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0045"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="sacE"
                     /protein_end="3638"
                     /protein_start="3618"
                     /score="30.3"
                     /tool="antismash"
                     /translation="MYVIYTSGSTGRPKGVVVPH"
     CDS_motif       17370..17396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0046"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="sacE"
                     /protein_end="3766"
                     /protein_start="3757"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGLTEATVN"
     CDS_motif       17502..17591
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0047"
                     /evalue="3.90E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="sacE"
                     /protein_end="3831"
                     /protein_start="3801"
                     /score="47.9"
                     /tool="antismash"
                     /translation="PPGVVGELYVSGRGLARGYIGQSALTASRF"
     CDS_motif       17676..17741
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0048"
                     /evalue="4.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="sacE"
                     /protein_end="3881"
                     /protein_start="3859"
                     /score="37.7"
                     /tool="antismash"
                     /translation="FLGRVDTQVKIRGFRIELGEIE"
     CDS_motif       17940..17966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0049"
                     /evalue="4.40E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="sacE"
                     /protein_end="3956"
                     /protein_start="3947"
                     /score="4.0"
                     /tool="antismash"
                     /translation="GKLDRRALP"
     aSDomain        18021..18215
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_PCP.4"
                     /evalue="6.40E-22"
                     /label="sacE_PCP.4"
                     /locus_tag="sacE"
                     /protein_end="4039"
                     /protein_start="3974"
                     /score="69.4"
                     /tool="antismash"
                     /translation="KAIAELFAELLGVSPGIHDNFFTLGGHSMASMRLVGKIRSVFGVD
                     IALRDVFDSPTVAGLAGRLT"
     CDS_motif       18078..18107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0050"
                     /evalue="2.80E+01"
                     /label="PCP_mE"
                     /locus_tag="sacE"
                     /protein_end="4003"
                     /protein_start="3993"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="NFFTLGGHSM"
     CDS_motif       18270..18293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0051"
                     /evalue="1.40E+01"
                     /label="C1_dual_004-017"
                     /locus_tag="sacE"
                     /protein_end="4065"
                     /protein_start="4057"
                     /score="-0.3"
                     /tool="antismash"
                     /translation="PLAPVQRG"
     aSDomain        18309..19070
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sacE_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.20E-58"
                     /label="sacE_Condensation_LCL.2"
                     /locus_tag="sacE"
                     /protein_end="4324"
                     /protein_start="4070"
                     /score="189.0"
                     /tool="antismash"
                     /translation="HALALRATTPFDVPALVDAYADVVGRHEPLRTVLDGGVQRAVPVP
                     PLEVEPVVALDEALPAFAAEPVEPGRPPVRARLVVDASGAQALLLTMSYLAVDEWSVVP
                     LFRDLQHAYAARRRGEAPQWTELPVTYADYALWSREVVESVGERQHAFWRDALRDLPDL
                     ALPYVGDRRPGRHPAAVIPFELPASLHAAIDRLATRTGTSMFMVVQAAVAAALTPYGTD
                     LPIGTMVAGRTEEALADLVGCFFNRVVLRTDT"
     CDS_motif       18315..18407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0052"
                     /evalue="3.80E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="sacE"
                     /protein_end="4103"
                     /protein_start="4072"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LALRATTPFDVPALVDAYADVVGRHEPLRTV"
     CDS_motif       18594..18647
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0053"
                     /evalue="2.00E-03"
                     /label="C3_LCL_132-143"
                     /locus_tag="sacE"
                     /protein_end="4183"
                     /protein_start="4165"
                     /score="10.9"
                     /tool="antismash"
                     /translation="AVDEWSVVPLFRDLQHAY"
     CDS_motif       18699..18728
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0054"
                     /evalue="4.10E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="sacE"
                     /protein_end="4210"
                     /protein_start="4200"
                     /score="10.0"
                     /tool="antismash"
                     /translation="YADYALWSRE"
     CDS_motif       18972..19061
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sacE_0055"
                     /evalue="1.10E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="sacE"
                     /protein_end="4321"
                     /protein_start="4291"
                     /score="27.5"
                     /tool="antismash"
                     /translation="DLPIGTMVAGRTEEALADLVGCFFNRVVLR"
     gene            19427..19621
                     /gene="sacF"
     CDS             19427..19621
                     /codon_start=1
                     /gene="sacF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 110.2; E-value:
                     4.9e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="MbtH-like protein"
                     /protein_id="QYI86763.1"
                     /transl_table=11
                     /translation="MTNPFEDPEGRFHVLVNDEGQHSLWPSFADIPAGWTTRFGPDTRD
                     ACVAYVEEHWTDLRPLSLR"
ORIGIN
        1 tcaggcccgg gtgcccgacc aggccgccca cagctccgcg taacggccgc ctgcggccag
       61 cagttcctcg tgcgggccgc tctccaccac ccggcccgct tccagcacga ccacgcggtc
      121 cgccgtcatg gcctgggtga gccggtgcgc caccagcagg ccggtccgcc cgtccaacgc
      181 ccgcgccgcc ggctcctcca actcccgcgc gcccgcgctg cccgcgtccg cggtcgcctc
      241 gtccaggatc gccaccggcg gatcggccag cacgagccgg gccagcgcca actgctgcgc
      301 ctgcgtcacg gtcagccggt gcccgccctc gccgaccacg gtgtccaggc ccgacggcag
      361 cgcggaggcc cagtcgagcg caccgacccg cgccaacgcc gccgagagct cgtcgtcggt
      421 ggcgtccggg cgggccagcc tcaggtcgtc ggccagcgga ccggcgaaga cgtgcacctc
      481 ctgcgtgatc agcgcgaccg accgcaccgc cgaccccagc tccaccccgc cgatgtggat
      541 gctcccggtg gtcggctcgt gcacgcccgc gatcagcttc gccaacgtcg tcttgcccgc
      601 gccggaggcc ccgaccagcg cgacccgctc accggcggcg agctccaggt cgacgtcccg
      661 caacaccgga tgaccgtcca gataggagta ggagaccccg gccagcttga tcgtggtgtc
      721 cgccggccgc acccggccct ccagcacggg catcggctcg tcggtcacgc ccaccagccg
      781 ggacagcgac gcggtggcgg cctgcgcgtc gtcggccagc gccagggcgg cgttgaccgg
      841 gttgaacagg ctgtggaagt acagggccgc ggcggtcgcc gtgcccaccg acgccgagcc
      901 ggcgccgacc agccagaaac cggtgaccag cacgccggcc aggccgatga actcggccgc
      961 gttcagccga ccgtagaacc gggtcagcag ccggatgccg cgcaacgcca ggtcgaccgc
     1021 cgcccgcgac cgcgaccgca cctgcgccac gtgcgccgag gccagcccga acgtccgcac
     1081 ggtcgccgcg ccgccgatgg aatccagcaa ctgctgctgc tggacgccca cggccacccg
     1141 ctgcgccgcg tacagctcca cggcccgtcc gccgtaccac cgcacggtgt gcacgtggat
     1201 cggcatcgcc agcagcacag ggaccaggaa ccgccagtcc agcaccgcga tgccgaccac
     1261 ggtcagtccg atggtcaacg ccgaccgcgc catcaccggc agcgcgttgc gcaccgcgtc
     1321 cgcgatcacc tgcacgtcac gcgtcacccg cgaggtcagg tcgcccgagc ccgccgcctc
     1381 cacccgcccc agcggcaggt gcagcgcccg ctccacgaac ttctcgcgca ggtcggcgag
     1441 catcccctcg cccagccgcg ccaccaacga cgtgccgaac gccgtcgaca cgccctggac
     1501 ggcggcgacc agcgccaaca ccgccacggg ccaggtgatg gcggaggacc ccgcgccgac
     1561 caggtccacg atccggccca gcaccggcgc ggtgagcaac ccgaccgccg tgcccgccag
     1621 cagcaccagc aacgccgccc acgccaccgc gcggcgcggt cggaccagct cgccgaccac
     1681 cgcccaggtc cgggctccgg aagcggtcgc cagcaactcg cgcatcagct cgacaccacc
     1741 agtcggcacg tctcgtcggt cgtcaggccg gcccgcatca gctcaacacc accagtcggt
     1801 agtcctcgtc cgccaccagg tccgcgtgcg cgccggacga gacgacgaca ccggaagcca
     1861 ggaacaccac gcggtccgcc gcggccagca gcgccgggct cgtcgccacc acgatcgtcg
     1921 tcagccccgc cctcatccgc ttgatcccgg cggccagcga cacctccgtc accgcgtcca
     1981 ccgcggtcgt cgggtcgtgc accacgagca ccgggggagc ggcggccagg gcgcgcgcca
     2041 gcgccacccg ctgccgctgc ccacccgaca gcgaccggcc gcgcgccgag atcaccgtgt
     2101 ccaccccgtc gggcaaggcc cgcgccacgt cgtccacccg tgccgcgtcc atcgcctcgc
     2161 ccaccagcgt tccgccggcc gcgacgttgt cccggaccga gccctcgaaa aggtccgcgt
     2221 cgtgcgccgc gaccaacacc gccgcccgca gcgccgaacc ctccacagtg gacagcggca
     2281 acccgtccag cgccaccgtg ccgtcctcgg ggtccacctc gcgcgccagc acggccagca
     2341 acgacaccgc gtccgccggg tcgcgcgcca ccacgccgag cagctcgccg ggtgacgccg
     2401 tgaacgacac gccgcgcaac gaccccgaca ccacgtcggc cagttcaacc cgcccggcca
     2461 cggtgggcgg caggtgcgac gaaccgggcg gcacgtccgg tggcgcggac agcacctcgg
     2521 ccacccgtgc ggccgacgcc cggccctgcg ccagcagccc gttgacccac gcgaagatcg
     2581 acagcggcca cagcaggaac tgcgccaacc cgaccgccgc caccagctcg cccacggtga
     2641 tcgtgccgga cgcggccaag tgcccgccga ccagcgccac gaccgccagg aacacgccgg
     2701 tcatcgcgag catcgagccg tccagccagg cccgtgacct ggccgcgcgg atcgcggcgg
     2761 ccatggacga ccggctggtc acccggtacc gccgcgccgc cgtcgcctcc gcgccgatgc
     2821 ccttcaacgc ccgcagcccg gccaccaggt cggccgccac cccggacgcc agcgcggccc
     2881 ggtcctgctc ggcgtcgctg cgccgttcga gtggtttgcc gagcacgtgc gccaggccga
     2941 gcaggaccgg cgcggccacc agcaccaaga ccccgagcac ccacgacacc cgcagcaacg
     3001 ccaccgcgcc caccagcacc ccgatcaccg cggagaacgc gatcggcaac gccaggttca
     3061 cctgcccgac gcgctgcgcg tcgctggtcg cgatgttcgc cagctcgccg gacagcctgc
     3121 cgcgcgccgc gccgccgtcc gccgacagca cccgcgcggc caacgtcgac cgcacctcgt
     3181 gcgcggcctg gtgcgacgcc ttctccccgc tgcgcaagga gaagcggaag ctcagcgaca
     3241 gcgtcacgaa caccgcggcc agcacgccga tccagaggac cagtcgcccg ctcgcgccgg
     3301 tgcgcaccgc ctcgtcgatc accacgccga tgagcagcgg cacggcggcc tcgccggcct
     3361 ggtgcgccgc gccgagtgcc gaggcgacgg tcaccgacct ccactgcccg gtcacggccc
     3421 ccttgaggac ctcggtcctg tggacggttc tcacccggtg cccgccttcc gctgaagtgc
     3481 taggtgaggc taccctaatc acgagagagg cctggatcac tcccgcgaag gatcaactta
     3541 ggttagggta accaaagttc gatcacccgc tttcgcaccg atgggacagc catgccacag
     3601 ccaccagtct tcgacgtcct cggcgtcggc ttcgggccgt ccaacctggc cctcgcgatc
     3661 gccgtcaccg agtacaacgc cgacgcgcgt gccgaagacg tggtgaccgc ccacttcctg
     3721 gaacggcagc cgcgcttcgg ctggcaccgc gggatgctga tcgacgacgc gaccatgcag
     3781 gtgtcgttcc tcaaggacct ggtgacgctg cggaacccgc acagcacctt caccttcctg
     3841 agctacctgc acagcagggg caggctggtc gacttcatca accacaagaa cctgttcccg
     3901 ctgcgcgtcg agttccacga ctacttcgag tgggccgccg gccgcgtcga cgacctggtg
     3961 tcctacgacc acgacgtggt ggacgtgcgg ccggtgaccg aggacggcgt gatcacgcac
     4021 ttcgacgtcg tctcgcgcac gtccaccggc gaggtggagg tgcgccgcgc tcgcaacctg
     4081 gtgctggcca ccggtctgcg cccggcgttg cccgagggcg tccggccgtc cgcgcgggtc
     4141 tggcacaacc gggacttcct gcaccgcgtc gagtcgctgg ccgacccgcg ccggctcgtc
     4201 gtcgtcggcg ccgggcagag cggcgccgag gtcaccgcgt tcctgcacga gcggttcccg
     4261 gccgccgagg tgtgcgcggt gttcgcccgc tacggctaca gcccggccga cgacagctcg
     4321 ttcgcgaacc ggatcttcga ccccgccgcc gtggacgact acttcgccgc gcccgagcag
     4381 gtcaagcgca agctgatgga ctaccacggc aacacgaact acgcggtcgt cgacaacgag
     4441 ctgatcgccg agctgtaccg gcgggtgtac cgggagaagg tggtggggcg gcagcggctg
     4501 cggctgctca acctctcccg cgtcgccgag ctggacgacc gcgaggacgg cgtggcggtg
     4561 accgtggagt cgttgagcac cggcgcgcgt gaagtgctcg acgccgacgc gatcgtctac
     4621 gccaccggtt accgcgaggc cgacccgacc gggctgctgg gcgagctggc cgggcgctgc
     4681 gcccgtgacg cgcacgacag gctcagcgtc ggccgcgact accgcctgga caccgacgac
     4741 gacctgtcgg ccggcctcta cctccagggc ggcaccgagc acacgcacgg catctcgtcg
     4801 tcgttgctgt ccaacacgtc cgtgcgggtg ggggagatcc tccagtccgt gctcggccgc
     4861 cgcgtcccgg tggcccccgt gcaaccggaa tacgcgatca gcgtctcacg ggtgggctga
     4921 accccctcgt tgtttgttag gttatgcaaa cctaagctgg tacagcggcg cgccgccgcg
     4981 cctccgaaag ggaaaccctg tgatgtccac gaagttcaag ctggtcgcgg ccgtgtcggt
     5041 cgcggcgctg gcgctggccg cctgcggggg cggcggcgac gccggcaccg gtgggacgag
     5101 cgagaacgcc gccgccaccg gcgcgttccc ggtctccgtc gagcacgagt acggcaccac
     5161 cgagatcaag gccgagccga agaaggtcgt cacgctcggc ctgtccgacc aggagccggt
     5221 gctggccctg ggcgtcaagc cggtcggcgt cgtggactgg ttcaaggagc ggccgtacgg
     5281 caactggccg tggaccaagg aactctgggg cgacacgcag cccgaggtcg tcggcgagcg
     5341 cgacgagtac aacctggaga aggtcgccgc gctcaagccc gacctgatcc tcgccgtcta
     5401 ctccggcatg aagcaggagc agtacgacac cctgtccaag atcgcgcccg tggtcgcgca
     5461 gcccaaggcg ttcccggact acgccgcgcc gtggcaggac cagaccttgc acatcggcaa
     5521 ggcgctgggc aaggaggagg aagcgcaggc gctgatcgac ggcgtggcga agcggttcgc
     5581 cgacgccaag gccgcgcacc ccgagtgggc cggcaagacg atggtggtgg ccgacagctt
     5641 caagcccggc cagtactccg cgttcgcgcc gaccgacccg aaggccatct tcatgaagga
     5701 gttgggcttc accctcgtgg acgagatcgg caagctcgcc ggccagctca acgtggccga
     5761 gttcagcgag gagcggttcg acctgctcga cgccgaccgc ctggtgtggc tcatgttcga
     5821 ccagagcgcg tgggagcggg tcaagtccgt gcccgcctac cagcggctcg aggtcgtcag
     5881 cgagaagcgc gacctgttcc tcacctacat ggacccgccg atcggcgcgg ccatgtcgtt
     5941 caacacggtg ctgagcgtgc cctacggcat cgaccaggtc gtgccgctgc tcgaagcgat
     6001 caagaactag tcggcggtcc accgcgggtg tgggtgccga cggcatcccc acccgcggtg
     6061 tgtgtgcggg aaatcgggaa agaacgggaa ggttgaccat ggcgctgccc ctgaccggtg
     6121 ctcagaccgg tgtctggttg gcacagcagc tggagcccga caaccccgtc tacaacgtgg
     6181 cgtggtacct ggagctgcgc ggaccggtcg accacgaccg gctggcggcg gccgtccggc
     6241 agacgatcgg cgagaccggc gcgctgcacg tccggttcac cggggacggc caggtcccga
     6301 cgccgccgac caccgacctc acgctgctgt cgttcgactc gctcgccgac gcgcgggcgt
     6361 ggatggacga cgacatggcg cggctgaccg acatcgccac cggcccgctg ttccaccacg
     6421 cgctgctgcg catcgccgac gaccacgtgc tctggtacca gcgctaccac cacctcgtgg
     6481 tcgacgccta cggctgcgtg ctgatcaccc gccgggccgg cgagctgtac gagggcgcca
     6541 ccgagccgcg gccgaagccg gtgcaggcgc tggtcgacgc cgacctcgcc taccgcgact
     6601 cgccggaccg ggacgccgac cgggcgttct ggcacgcgaa gatggccgac cgccccgagc
     6661 cggtgcggct cgtgccgcgg gccgccgggc aggtccgcga ggtcatccgc cgcaccgtcg
     6721 agctgccgaa cccgttgacg tcacggcagg tcatcgccgc cgtcgccacc tacacccacc
     6781 gcgtgaccgg cgcgtccgac ctggtgctgg ccatgccggt gaccggtcgg cgcgacgccg
     6841 tcagccgggt cacgcccggc atggcgtcca ccgtgctgcc gctgcgcgtc accgtgcggc
     6901 cggacagcac catcaccggc ctgatcgccg acgtcgaccg cgagatccgc gaggtcgtcc
     6961 cgcgcagcgc ctaccgcggc gaggacctgg cccgggagct cggcctgcgc gacggcatcc
     7021 ccgagctggt cggtccgacg gtcaactacc tgggcttcgg ccgggagatg ggtttcgccg
     7081 acctcgaccc cgcgttccac atgctgtcgc tgggaccggt caacgacctc accacgtcct
     7141 tcctgcgacg cgccgacggc cggctggtcg tgacgttcga ggcgaacgcc gccgtgtgca
     7201 cgccggcgga actggccgac caccagcgcc gcttcctgcg cgtcctcgcc gccgaccccg
     7261 accagccggt ggcgttgatc gacctggtgg acgacgcgga acgcgcccgt ctgctggact
     7321 tcggcacgtc gccgcgcgag gtggacgagg tgacgtggcc cggcgcgttc gagcgccagg
     7381 ccgcgctgcg cccggacgcc gtcgcggtgg tgtgcgagga cgtgacgctg acctacgccg
     7441 agctgaacgt cgccgcgaac cggctggccc gtgcgctcgt cgcctcgggc gtgcgggccg
     7501 aggacgtggt gggcgtggcc ctgccccgat cggccgacct ggtcgtcacg ctgctcgcgg
     7561 tgatgaaggc gggcgcggcc tacctgccgc tggacctcga ccacccgcgt gaccgcgtcg
     7621 accacatggt cgccgacgcg ggcgcgacgt tggtcatcac gccggagacg cggttcgagc
     7681 tgcccgatga cggctcggac ctggggctgg acatcgcgct ggaccaggcc gcgtacgtga
     7741 tctacacgtc cggctcgacc gggcggccca agggcgtcgt ggtgacgcac gaaggcatcg
     7801 gcagcctcgt cgcgaccgcg ctggaccgga tcgggatcac accggacagc cgggtcgtgc
     7861 agttcgcgtc cgtcgggttc gacgtggccg tgtgggacct gtgcatgtcg ctcggcgtcg
     7921 gcgggcgtgc ggtcctcgtg ccgtcgcacc ggcgggtcgc gggcgaggag ttgacctcct
     7981 acatcgccga acaccgcgcc acgcacatga tcctgccgcc gtcgctggtg gccgcgctgc
     8041 caccggagtg cgagctgccc gccggcgcgg tgctgatcgt cggcacggag accgtgccga
     8101 ccgagctgat cgcccggtgg gcccgccggt tgcgggtcgt cgccgcgtac ggcctgaccg
     8161 aggccacggt gaactccacg ctgtgggccg cccggccgga ctggaccggt ccggtgccga
     8221 tcggcgtgcc ggacccgaac acccgctgct acgtgctgga ctcggcgttg cggccggtgc
     8281 cggtgggcgt cgagggcgag ctgtacgtcg gtgggcgcgg gctcgcgcgg gggtaccggg
     8341 ggcaggcggc gctgaccgcg tcccggttcg tggccgaccc cttcgccgga ccgggttccc
     8401 gcatgtaccg gacgggcgac cgggcccggt ggcgcgccga cggcaacctc gacttcctgg
     8461 gccggtccga cggccaggtg aagatccggg ggttccggat cgagccgggc gaggtcgaga
     8521 gcgtgctcat ggcgcacccg gcggtcgcgc aggccgccgt gctggtgcgg gaggaccacc
     8581 ggcgggtgaa gcggctcgtc gcgtacgtgg tcggcacggc ctcgccggtg gacgcgcggg
     8641 agcacgtcgc ctcggcgctg ccggactaca tggtgccatc cgtggtggtg ccgctgcccg
     8701 ggccgctgcc gctgaccccg aacggcaagc tggaccgcgc ggccctgcca gagccggact
     8761 ggaccgcgcc ggccggtgac gccccggcca cgaacccggt cgagcagacg ttggtggccc
     8821 tggtcgaggc ggtgctcggg gtgactcccg gcatccacga caacttcttc gagctgggcg
     8881 gcgacagcat cgtcacggtg cagctggtgt cgcgggcgcg tgaggcgggc ctggagttca
     8941 cgccgcgcga ggtgttcgag caccggaccg tggccgggtt ggcgcgggtg gcgcgcgcgg
     9001 tgagcggggt cgacgtctcc ctcgacgggt tctcgtcgga cgtgctgccg gcgtcaccgt
     9061 tgcaagaggg cttcttcttc cacgcgcgct acgacaccga tgactcgtac gtcgtgcagg
     9121 aagtgctgag cctggccgtc gaccgggacg ccgtgcaggg cctgctggac cggcacccgt
     9181 tgctgcgggc gggtttccgc cagaccgatc gcgggcgcgt ggagcaggtg atcgcggagg
     9241 cgttgacgct gccgtggcgc gactacccgg ccaccgacga cgtcgaggcc gtgctggcgg
     9301 ccgagcgcgc cgaacccttc gacctgtccc ggccgccgtt gatgcgcgcg gcccggcacg
     9361 gcgaccggct ggtgctgacg ctgcaccaca tcctgctgga cgggtggtcg gtcgggctgc
     9421 tgcggcgtga gctggtcggt gggcggctgg cgccggtcga ccaccggcgt tacttcgcgt
     9481 ggctggcgag ccgtgaccgt gccgcggcgc acgaggcctg gcgcgcggct ttgtccgatg
     9541 tggacgagcc gacccggatc gccgggttgt ccacaacctc tcccgtgcga cccggaatcg
     9601 tcggtgccag ccggcagaat cacagcaggg gtcccctggg aggggacgtc cgcgaagcac
     9661 tgccgttggc cgaggtgtcg ccgcggcacg ggcagcaccg ggttcggttg gccgccgagc
     9721 tcagcgcggc actcgtcggt gaggcgaggc ggcgcggtct gacgctcagc accgtcctgc
     9781 acggcgcgtg gggcctgctc ctcggtggtc tcaccggtcg ggcggacgtc gtgtacggca
     9841 ccaccgtggc gggccggccg gccgaggtgc cgggcatcga gaacgcggtc gggttgttca
     9901 tcaacacggt gcccgtccgg cagcgctggc ggggggacga cagcctggcg accaccttcc
     9961 agcgcctgca gggcgagcag gcgcggctgc tggaccacca gcacctcggg ctcgccgaga
    10021 tccagcgcgt caccgggcac ggcgagctgt tcgacaccct cgtcgtggtc gagaacttcc
    10081 ccgacgtggt cgacgacgtc gagatccgcg accaggtgca ctacccgctg gccctgatcg
    10141 cgctgcccgg cgaacgtctc gaactgcgcc tcaagcaccg cctccccgac gccgaagtgg
    10201 cctccctcgc gcaacggctg gtccggctgc tgaccgcgtt cgcgaccacc cccgaccggc
    10261 cggtggcgag cctcgacctc ctctccgaca ccgaaaccga gtggctggca cggctcaacg
    10321 cgaccaccgc cgacgtgccg gaaggcacgc tcgtcagccg gatcgccgcc cagaccgccc
    10381 gcacccccga cgccgtcgcg gtcgtctacg agaacatcac cctcacctac gccgaactgg
    10441 accggcgcgc caccgcactg gcccgcacgc tgcacggcca ccgcgtcgtc ggcgtcgccg
    10501 tgccgaggtc cgcggaactg ctggtcgcgc tgctggccgt gctcaagtcc ggcgccgcct
    10561 acctgcccct cgacctcgac tacccggccg agcgcgtcga gttcatgctg gccgactcgg
    10621 gcgccaccgc ggtcatccgg cccgaggact gcgtcgacac cggaaccccg ccggtcgacc
    10681 tcccggcacc ccacccggac cagcccgcct acctgatcta cacctcaggc tcgaccgggc
    10741 ggcccaaggg tgtcgtcgtc acgcaccggg cgatcgtgaa ccggctggcg tggatgcagc
    10801 acgagtacgg cctcaccgcc gacgaccgcg tcctccagaa gacaccgtcc agcttcgacg
    10861 tctcggtgtg ggagttcttc tgggcgctgt gcgaaggcgc ggccgtggtg ctcgccaagc
    10921 cggacggcca ccgcgacccc gcctacctcg ccgacctgat ctgccgcgag cgcatcacca
    10981 cgctgcactt cgtgccgtcc atgctggccg cgttcctcgg cgtccccgaa gcgcacgacg
    11041 acaaatcgtg gtcgacgagc ctgcgccgtg cgttcagcag cggcgaggcg ttgaccggcg
    11101 acgtggccgg ccggtggctc gaactcaccg ccgtgccgct gcacaacctg tacggcccca
    11161 ccgaagccgc cgtcgacgtc acgtacttcg agtacgacgc cgcgccggac cctgccgtgc
    11221 cgatcggccg cccggtctgg aacacgcggc tgcacgtgct cgacccgttc ctgcggcccg
    11281 tgccggcgaa cgtgccgggc gagctgtacc tggcgggcgt ccagctcgcc ctcggctacc
    11341 acgggcggtt cgcgctcacc gccgagcggt tcgtggccga cccgttcggc gcaccgggcg
    11401 aacgcatgta ccgcacgggc gacctggtgg tgcgccgccc ggacggcgtg ctggtctacc
    11461 tcggccgcac cgaccggcag gtcaaggtgc gcggcaaccg gatcgagctg ggcgaggtcg
    11521 agtccgcgct ggtcaagcag cccggcgtgc ggcgggccgc ggtcatcgcc cgcggtgacc
    11581 agctcctcgg ctacgtgacg ccggccgacg tcgacctcga cgcggtgcgg tccggtgtcg
    11641 ccgccgccct gcccgccgcg atggtccccc acgcggtcgt ggcgctgccc gacttcccgc
    11701 tcacccccag cggcaagctc gaccaggacg cgctgccctc gccgaccctc gcgaagaccg
    11761 gacgacgcgc gccggccacc gaccgggaac gcctgctggg cgaggtgttc gccgacgtgc
    11821 tcggcctggc cgacctcggc gtggacgacg acttcttcgt gctcggcggt gacagcatca
    11881 cgtccatcgc ggtgtccagc cgggcacgcg ggctcggcat cgggatcagc ccgcgtgacg
    11941 tgttcgaaca ccgcacggtc gccgcgctgg ccgccgtcga gacgaccgcg gacaccgccg
    12001 ccgacgcgcc gctgctggtg ctgaccgagg accaacgtgc cgccctgccc gaggcggagg
    12061 acgtgtggcc gctctcgccg ttgcaggaag gcctgtactt ccacgccagc tacgacaccg
    12121 gcgcgctcga cgtctacctc tcccaggaga cgatggactt cgcgggccgg ctggacgtcg
    12181 accggctgcg ccgcgcgggc gccgcgctcc tggcgcgcaa cccgagcctg cgcgccgggt
    12241 tcaccagcga cggcgtgccg gcaccggtgc agttcatcgc gcccggcctg gagatcccgc
    12301 tgcgcgtggt cgaagccgac gacaccgagg ctccggagct gctggccgcc gaccggcgtg
    12361 agcggttcga cctggccgcg ccgcccctgt gccggttcct ggtgctgcgg ctgcccgacg
    12421 gccgcgaccg gctcgtcatc acccaccacc tgatcctctg ggacggctgg tcggcgtggc
    12481 tgttcctgga gcagctgctg gagctgtacc gggacgtcga cgccgagctc ccgccgcccg
    12541 gcacctaccg cgactacctg gcgtggctgg cccggcagga ccacgacgcg gcgctgcggg
    12601 cgtggcgcac ggcgctgtcc ggcctgcgtg agccgacgct ggtcgcgccc gtcgaccggt
    12661 cacgcgagcc ggtcatcccg gccgagttcc accaggagct gagcgaggag ctgaccgacc
    12721 gcgtccgggc gcgggcccgg cagcacggcc tgaccgccaa cgccgtgttc aacaccgcgt
    12781 gggcgatggt gctggcgagc caggtcgggc gcgacgacgt ggtgttcggc accgccgtcg
    12841 cgggccgccc ggtcgaggtc gacggcgtcg agcacgtcat cggcatgttc ctcaacacca
    12901 tccccacccg catcgcgctc gacccgcgcg agaccgtgct ggagctgctg cggcgcgtcc
    12961 aggccgagcg gaccgcgctc atgtcctacg agcacgtcgg cctcggcgag atccagcggg
    13021 aggccgggca ccggcagctg ttcgacacgc tgttcgtgct gcgcaccggc gacggcgacg
    13081 accgccaggg cgagttcgcg tcccggcacg gcgtgctgga ggtgtccaac gtggacggca
    13141 cgcacttccc gctgacgctc atcatcaccc ccggcgcgcg cacccgcgtc acgctcgcct
    13201 cccggccgga cgtcttcgcc gccgacgccg ccgaagcgct gctcacccgg tacaccaccg
    13261 tgctgcgccg cctggtggac gcgccggacg cgctgatcgg caccctcgac gtgctgcccg
    13321 accacgagcg gcgcacgctg gtggccgagt gggacgccgg cgccaacccg atgatctccg
    13381 agaccgtcgc cgacctgctc gccgcccagg ccctccgcac cccggacgcc accgcgctcg
    13441 tgttcggcga ccagcggctg acctacgcgg agctgcagga ccggatcgac accctggccc
    13501 ggctgctgat cagccggggc gcggggccgg aacgcgtggt cgcgctcgcg ttgccgcgca
    13561 ccaccgagat ggtggtggcg ttgttcgcgg tgctccgcac cggcgccgcc tacctgccgc
    13621 tcgacctcga ccacccggcc gaccggctgc tgctgatgat cgaggacacc aagccgctgt
    13681 gcgtgctctc gaccacggcg gtcgggctgg tgccggacgc gttgtgcgtg gacgacctgc
    13741 ccgccgggcc ggaccacgtc gagtggccga cgttctcgct ggaccacccg gcgtacgtga
    13801 tctacacgtc gggctcgacc ggccggccga agggcgtcgt cacgccgtac cgcggcctga
    13861 cgaacatgca gctcaaccac cagcaggcga tcttcgcacc cgcgatcgcg gcggccggcg
    13921 gccggcggct gcgcatcgcg cacaccgtgt cgttcgcgtt cgacatgtcc tgggaagagc
    13981 tgttgtggct ggtcgagggc cacgaggtgc acgtgtgcga cgaggagctg cggcgggacg
    14041 cggcggccct ggtggcgtac tgcgacgaac acctggtcga cgtggtcaac gtgaccccga
    14101 cctacgcgca gctgctcatc gaggagggcc tgctggaagg gcacgtcccc gcgctggtgc
    14161 tgctcggcgg cgaagccgtg cccgaatcgg tgtggcagcg gctgcgcgag acgcccggca
    14221 cgtacggcta caacctctac gggccgaccg agtacacgat caacaccctc ggcgcttcca
    14281 cggaggacag cgcgacggcg accgtcggca aggcgatctg gaacacccgg gcgtacgtgc
    14341 tggacgcgca cctgcggccg gtgccgcccg gctcgcccgg tgagctctac atcgccggtg
    14401 tcggcctggc ccgcggctac cacgacaggt tcggcctgac cgcggagcgg ttcgtcgccg
    14461 acccgtacgg cccgcccggc acccgcatgt accgcaccgg ggacctggtg cgggcgcgtg
    14521 ccgtgtcctc gctcgacccc gcgagcaggt cctcggccgg gaacctggac ttcctcggcc
    14581 gcaccgacga ccaggtcaag atccgcggct accgggtgga acccggcgag gtcgagtcgg
    14641 ccctggccgg tcagccgggg gtgacgcacg cggcggtcgt cgtggacgcc ggtccgggcg
    14701 gggtgaagcg gctcgtcggg tacgtggtgt cgtcggtcga cccggtcgtg ctgcgggaca
    14761 ggctcaagac cagcctgccc gactacatgg tgcccgccgc gatcatgccg gtggacgcgc
    14821 tgccgctcac ggtgaacggc aagctcgacg tgcgggccct gcccaagccg gtggtcaccg
    14881 gcgcggcgtc gtcgcgggcc gccgccaccc gcgcggagga agtgctgtgc gggctgttcg
    14941 ccgacgtgct cggcgtgccc gcggtggggg cggacgacaa cttcttcgac ctcggcggcc
    15001 actcgctgct cgccacccgg ttgatcagcc gggcgcggtc ggcgctgggc gtggaactgg
    15061 cgatccgcga cctgttcgac gcgcccacgg tcgcggaact cgcgtcgcgg gccggtggcg
    15121 ggtcggcccg tccgccgctg gtggccgggc aacggcccgc cgagctgccg ctgtcgtcgg
    15181 cgcagcagcg gttgtggctg atccagcaga tggagggcac gtccgccgcc tacaacttcc
    15241 cgctggtgtt cacgctgcac ggttcactgg acgtggccgc gttcaccgcc gccgtcggtg
    15301 acgtggtcga ccggcacgag gcgttgcgga cggtgttcgg cgagcacgag ggcacgccgt
    15361 tccagcgggt gctgcacgac gtcgcgcccg tggtggtggt gcgttcggcc ggtgggcacg
    15421 aggtgccgga catcgtgcgt gccgaggtcg agcggccgtt cgacctgcgc gcggagctgc
    15481 cgctgcgggt cacggtcgcg tcgttggcgc cggaggagca cctggtcgtc atcctgctgc
    15541 accacatcac caccgacgag tggtcggacc ggccgttcct gcgcgacctg gcgacggcgt
    15601 accgggcgcg gcgggacggt gacgtgcctc tctggacgcc gttgcccgtg cagtacgcgg
    15661 actacaccgt gtggcagcgg gacgtgctgg agatcgtcgg cgagcagcag tcggacttct
    15721 gggcgcggac gctggccggc gcaccggaag agctggagct cccggtggac cggccacgcc
    15781 cgggacggcc gacgttccgc ggcgcggacc tggaagtggt gttcgagccg gcgtcggccg
    15841 acgcgctgcg ggcgttcgcg cagacgtccg gcgcttcgat gttcatggtg ttgcaggccg
    15901 ccgtcgccgc cctgctcggc cggctgggcg cgggtgacga catcccgttg ggcgcgccga
    15961 tcgcgggccg caccgacgag gcgttggacg acctggtggg cttcttcgtc aacacgctcg
    16021 tgctgcgggc cgacctgtcc ggcgacccga gcttcgccga ggtggtggcg cgggtgaagg
    16081 agacgtcgct ggccgcgttc tcgcaccagg acgtgccgtt cgaggccgtg gtcgaccgga
    16141 tcaacccgac ccggtcggcg gcgcgcaacc cgctgttcca ggtgatggtc ggctaccaca
    16201 gccggggcgg cgactcgggg acgttcgacg gcctgccggt gacgtgggtg ggccacgaga
    16261 ccaccaccgc gaagttcgac ctggtgttca gcttcaccga cgtggtcgac ggtccggtgg
    16321 tgtgccggct ggagtacgcg acggacctgt tcgaccgggt gaccgtgcaa cggctgggcg
    16381 cgcggctgac cacgctggtc gacgccgtgc tggccgcgcc gtccgccccg gtgagcgcgg
    16441 tggacctgct cgcgcccgac gagcggcggc gcgtggtgga cgagttcaac cggaccgcgc
    16501 gggcggtgcc ggaggagacg ttcacgacga tgttcgcccg gtgcgtcgcc gcgcggccgg
    16561 acgcggtcgc cgtggtcgac cgccaccgtt ccgtcgacta cgcctggctg gacgaccggt
    16621 ccgaccggat cgcccgactg ctcgcggccc gcggtgtcgg ccacgagtcg gtggtgggca
    16681 tcgcggtgcc caagtcggcg gacatggtcg ccacggtcgt cgccacgctg aagctcggcg
    16741 cggcctacct gccgctggac ctctcgcacc cggccgaccg ggtcgcgtac atgatccagg
    16801 actccggcgc gacgctcgtc gtcaccacac gggccgcgcc cgtgccggac gtcgccgaga
    16861 tcctgctcct cgactcggac gcggtgcgcg atgagctgtc cgccgagtcg gaggccgcgc
    16921 ctgcgaccgg gccccgatcg ttggactcgg cgatgtacgt gatctacaca tcgggctcga
    16981 ccggtcggcc caagggtgtc gtggtgccgc acgagggcat cgccagcctc gccgcgaccg
    17041 ccatcgaccg gatgggcctc accgccgaga gccgggtgct ccagttcgcg tccgtgggct
    17101 tcgacgtggc cgtgttcgag ctgaccatgg cgctgtgcgt gggcggacgg ctggtgttcg
    17161 cgccggacga ggtgcgcgtc gccggcccgg agctgaccga cttcctgcgc gaccggcgga
    17221 tcacgcacat gatcctgccg ccgtcgctgg tgtcggcact gcccgccgac tgcgagctgc
    17281 ccgagggctc caccatcctg gtcggcaccg agaccgtgcc gccggacgtg atcggccgct
    17341 gggccggccg gctcaccctg ctcgccgcct acggcctcac cgaggccacc gtcaactcca
    17401 ccctgtggaa ggccgtgccg gagtgggact cggccgtgcc gatcggcatc cccgacccca
    17461 acaccaccgt gtacgtgctg gacgaccggc tgcggccggt gccgcccggc gtcgtcggcg
    17521 agctgtacgt gtccgggcgc ggcctggcgc gcgggtacat cgggcagtcc gcgctgacgg
    17581 cgtcccggtt cgtcgcctca ccgttcggtc cgcccggggc ccgcatgtac cgcacgggcg
    17641 accgtgcgcg ctggcgtgcg gacggcaacc tcgacttcct cggccgcgtc gacacccagg
    17701 tcaagatccg gggcttccgg atcgagctcg gcgagatcga agccgccctg acccggcacc
    17761 cggacgtggc gcaggcggcc gtgatcgccg accgcacggg tgacgtgacc aggctcgtcg
    17821 cgtacgtggt cggctcgacc ggggacgacc tgcgcgcgct cgtcgccgaa cggctgcccg
    17881 agtacatggt cccggcgacg gtgatcttcc tggctggccc gctgccgctg acgccgaacg
    17941 gcaagctcga ccgccgtgcc ctgccgacac ccgactggtc cgcgctgacc ggcgacgacc
    18001 ggccggtgac gccggagcag aaggcgatcg cggagctgtt cgccgaactc ctcggcgtgt
    18061 cgccgggcat ccacgacaac ttcttcaccc tcggcggcca ctcgatggcg tccatgcggc
    18121 tggtcggcaa gatccggtcg gtgttcgggg tcgacatcgc gttgcgcgac gtgttcgact
    18181 cgcccaccgt cgccgggctg gccgggcggc tgaccggcgc cacgtcggcc cgcccgccgc
    18241 tgcgccgctt cgaccggccg gtggacctgc cgttggcccc cgtgcagcgg ggtccggtct
    18301 cctgggacca cgcgctggcg ctgagggcca cgacgccgtt cgacgtgccc gccctggtcg
    18361 acgcgtacgc cgatgtcgtc ggccggcacg agccgctgcg cacggtgctg gacggcggcg
    18421 tgcaacgcgc cgtgccggtg ccgccgctgg aggtcgagcc ggtggtggcg ctggacgagg
    18481 cgctgcccgc gttcgccgcc gagcccgtgg agccgggccg accgcccgtg cgcgcccggt
    18541 tggtcgtgga cgcgtccggc gcgcaggcgt tgctgctgac catgagctac ctcgccgtgg
    18601 acgagtggtc ggtcgtgccg ctgttccgcg acctccagca cgcctacgcg gcccgccggc
    18661 gcggtgaggc tccacagtgg accgaactgc ccgtgaccta cgccgactac gcgttgtggt
    18721 cgagggaagt cgtggagtcg gtgggggagc ggcagcacgc gttctggcgt gacgcgctgc
    18781 gcgatctgcc ggacctggcg ttgccctacg tcggggaccg acgacccggc cgccaccccg
    18841 ccgccgtgat cccgttcgaa ctgcccgcgt cgctgcacgc cgcgatcgac cgactggcca
    18901 cccggaccgg caccagcatg ttcatggtgg tgcaggccgc cgtggcggcg gccttgaccc
    18961 cgtacggcac ggacctcccg atcggcacga tggtggccgg ccggaccgag gaggcgctgg
    19021 ccgatctggt cggctgcttc ttcaaccggg tcgtgctgcg caccgacacc gccgggcagc
    19081 ccggctacac cgagctgctg gcccgagtcc gcgccaccga cctggccgcg ttcgaccacg
    19141 cggacgtgcc cgtgccggtc gagccgcagg tcatgatcgt ccaccacgag aaggcggtcc
    19201 tgtcgaccct ggaaggtggc gcgggctcgc tcgaagccgt cccgaccggc acgacccccg
    19261 ccgagctgac cgtcagcttc tacgaaccgc gggacgacgg cccggtgccg tgctacctcg
    19321 tctacgcgac cgacctgttc accgacgcca ccgcccacca cctggccgac gcggtgctgc
    19381 gccacctgca ccgagcgaca accgaccccg accggaggat ccagccgtga ccaacccgtt
    19441 cgaagacccc gaaggccgct tccacgtcct ggtcaacgac gagggccagc actcgctgtg
    19501 gccgtcgttc gccgacatcc ccgccggctg gaccacccgc ttcggccccg acacgcgtga
    19561 cgcgtgcgtc gcctacgtcg aggagcactg gaccgacctg cgccccctgt cgctgcgttg
    19621 a
//
