BGC0002426: deschlorosvetamycin A biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 52,935 nt. (total: 52,935 nt).
This entry is originally from NCBI GenBank MW810086.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002426
Short description deschlorosvetamycin A biosynthetic gene cluster from Streptomyces sp.
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MW810086.1
Compounds
  • deschlorosvetamycin A
  • svetamycin H
  • svetamycin A
Species Streptomyces sp. [taxonomy]
References
Chemical products information
deschlorosvetamycin A
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Chemical database entries
NPAtlas
svetamycin H
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Chemical database entries
NPAtlas
svetamycin A
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Chemical database entries
NPAtlas
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QXL90809.1
 126 - 935 (+) hypothetical protein
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  • QXL90810.1
 932 - 1999 (+) hypothetical protein
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  • QXL90811.1
 2155 - 3336 (+) hypothetical protein
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  • QXL90812.1
 3382 - 4137 (+) L,D-transpeptidase
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  • QXL90813.1
  • babR1
 4334 - 5893 (+) sigma-70 family RNA polymerase sigma factor
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  • QXL90814.1
  • babR2
 5921 - 6991 (-) AsnC family transcriptional regulator
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  • QXL90815.1
  • babT1
 7176 - 8567 (+) MFS transporter
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  • QXL90816.1
  • babA
 8564 - 9775 (+) amidohydrolase
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  • QXL90817.1
  • babR3
 9795 - 10580 (+) DeoR/GlpR transcriptional regulator
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  • QXL90818.1
  • babB
 10614 - 10991 (+) hypothetical protein
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  • QXL90819.1
  • babC
 10988 - 11656 (+) NUDIX domain-containing protein
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  • QXL90820.1
  • babD
 11683 - 12561 (+) NAD(P)-dependent oxidoreductase
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  • QXL90821.1
  • babO1
 12583 - 13800 (-) cytochrome P450
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  • QXL90822.1
  • babO2
 13854 - 15473 (-) FAD-binding monooxygenase
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  • QXL90823.1
  • babM1
 15791 - 16525 (+) methyltransferase
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  • QXL90824.1
  • babO3
 16555 - 18186 (-) FAD-dependent monooxygenase
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  • QXL90825.1
  • babM2
 18186 - 18932 (-) methyltransferase
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  • QXL90826.1
  • babR4
 19489 - 20079 (-) TetR family transcriptional regulator
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  • QXL90827.1
  • babT2
 20160 - 21752 (+) MFS transporter
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  • QXL90828.1
  • babE
 22192 - 22932 (+) glyoxalase
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  • QXL90829.1
  • babM3
 23004 - 24038 (-) O-methyltransferase
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  • QXL90830.1
  • babF
 24103 - 24801 (-) 3-oxoacyl-(acyl-carrier protein) reductase
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  • QXL90831.1
  • babT3
 24785 - 26122 (-) potassium transporter
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  • QXL90832.1
  • babH1
 26122 - 27399 (-) halogenase
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  • QXL90833.1
  • babG
 27443 - 27799 (-) cyclase
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  • QXL90834.1
  • babI
 27796 - 28287 (-) polyketide cyclase
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  • QXL90835.1
  • babJ
 28284 - 28523 (-) putative acyl carrier protein
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  • QXL90836.1
  • babK
 28560 - 29819 (-) keto-acyl synthase beta
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  • QXL90837.1
  • babL
 29816 - 31081 (-) polyketide beta-ketoacyl synthase alpha
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  • QXL90838.1
  • babN
 31078 - 31479 (-) polyketide WhiE II
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  • QXL90839.1
  • babP
 31476 - 32153 (-) WhiE protein
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  • QXL90840.1
  • babT4
 32272 - 33747 (-) MFS transporter
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  • QXL90841.1
  • babR5
 33862 - 34527 (+) transcriptional regulator TetR family
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  • QXL90842.1
  • babM4
 34490 - 35545 (+) methyltransferase
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  • QXL90843.1
  • babR6
 35571 - 38414 (-) LuxR family transcriptional regulator
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  • QXL90844.1
  • babR7
 38571 - 40472 (-) AfsR/SARP family transcriptional regulator
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  • QXL90845.1
  • babO4
 40623 - 41891 (-) RebP-like cytochrome P450
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  • QXL90846.1
  • babQ
 41916 - 45134 (-) chromopyrolic acid synthase
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  • QXL90847.1
  • babS
 45131 - 46594 (-) FAD-dependent oxidoreductase
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  • QXL90848.1
  • babH2
 46837 - 48426 (+) BabH2 tryptophan 7-halogenase
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  • QXL90849.1
  • babU
 48423 - 48950 (+) flavin reductase family protein
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  • QXL90850.1
  • babV
 48956 - 49639 (-) alpha/beta hydrolase
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  • QXL90851.1
  • babW
 49636 - 50124 (-) SnoaL-like domain-containing protein
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  • QXL90852.1
  • babX
 50186 - 51133 (-) zinc-binding dehydrogenase
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  • QXL90853.1
  • babR8
 51269 - 51901 (-) TetR family transcriptional regulator
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  • QXL90854.1
 52200 - 52559 (+) hypothetical protein
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  • QXL90855.1
 52594 - 52812 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Entry added
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added chemical structures for compounds: deschlorosvetamycin A, svetamycin H.
  • Added NPAtlas links to compounds: deschlorosvetamycin A, svetamycin H.
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