BGC0002429 - 1 region(s) - antiSMASH results

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS,terpene,terpene-precursor	1	91,639	High	higginsianin B/higginsianin A/higginsianin C/13-epi-higginsianin C/higginsianin D/higginsianin E	PKS:Type I+terpene:Diterpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 91,640
Label		BGC0002429

Tailoring functions

Oxidoreductases: dehydrogenase

CH63R_05477: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

CH63R_05479: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Ligases: synthase synthetase

CH63R_05473: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

CH63R_05480: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002429.3	1.29	PKS, terpene	higginsianin B, higginsianin A, higginsianin C, 13-epi-higginsianin C, higginsianin D, higginsianin E	Colletotrichum higginsianum IMI 349063
BGC0002427.2	0.42	PKS, terpene	subglutinol A, subglutinol B	Metarhizium robertsii ARSEF 23
BGC0002603.2	0.37	PKS	chevalone E	Aspergillus versicolor
BGC0001082.4	0.35	terpene	Paxilline, 21,22-diprenylated paxilline	Penicillium paxilli
BGC0001284.4	0.33	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001273.3	0.33	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.32	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002191.2	0.32	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002604.2	0.31	PKS	sartorypyrone A	Aspergillus felis
BGC0000037.4	0.30	PKS	cichorine	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002429.3	1.00	PKS, terpene	higginsianin B, higginsianin A, higginsianin C, 13-epi-higginsianin C, higginsianin D, higginsianin E	Colletotrichum higginsianum IMI 349063
BGC0001284.4	0.66	PKS	alternariol	Parastagonospora nodorum SN15
BGC0001273.3	0.66	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002191.2	0.66	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0000037.4	0.64	PKS	cichorine	Aspergillus nidulans FGSC A4
BGC0002192.3	0.63	PKS	FR901512	fungal sp. No.14919
BGC0000107.3	0.63	PKS	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001258.3	0.63	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0002154.2	0.63	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15

Similar known clusters from MIBiG 4.0

Detailed terpene predictions

Terpene cluster 1 (21,678 - 42,500):

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
diterpene	polyketide diterpenoid		C20	unknown	OH

Genes with terpene domains:

CH63R_05476: TS_Pyr4

Domain 1 (1 - 242): Pyr4 type terpene synthase

Subtype: polyketide diterpenoid synthase, group a

Reactions:: epoxy_polyketide_diterpenoid → cyclic_polyketide_diterpenoid

Terpene cluster 2 (49,262 - 70,472):

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
diterpene precursor		GGPP	C20	acyclic	PP

Genes with terpene domains:

CH63R_05480: PT_FPPS_like

Domain 1 (28 - 315): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Geranylgeranyl diphosphate synthase

Reactions:: IPP, DMAPP → GGPP

Module view

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Detailed domain annotation

Selected features only

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Identified secondary metabolite regions using strictness 'relaxed'

Legend:

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
GGPP	Geranylgeranyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate