BGC0002435: coformycin biosynthetic gene cluster from Micromonospora haikouensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 49,762 - 74,294 nt. (total: 24,533 nt).
This entry is originally from NCBI GenBank FMCW01000024.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002435
Short description coformycin biosynthetic gene cluster from Micromonospora haikouensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: FMCW01000024.1
Compounds
  • coformycin
  • aristeromycin
Species Micromonospora haikouensis [taxonomy]
References
Chemical products information
coformycin
Copy SMILES
Chemical database entries
NPAtlas
aristeromycin
Copy SMILES
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • GA0070558_12444
  • SCF06432.1
 49762 - 50865 (-) Predicted arabinose efflux permease, MFS family
copy AA seq
copy Nt seq
  • GA0070558_12445
  • SCF06440.1
 51099 - 51917 (-) 5'-methylthioadenosine phosphorylase
copy AA seq
copy Nt seq
  • GA0070558_12446
  • SCF06447.1
 52009 - 52986 (-) GDP-L-fucose synthase
copy AA seq
copy Nt seq
  • GA0070558_12447
  • SCF06455.1
 53038 - 54504 (-) IMP dehydrogenase
copy AA seq
copy Nt seq
  • GA0070558_12448
  • SCF06463.1
 54514 - 55506 (-) adenosine deaminase
copy AA seq
copy Nt seq
  • GA0070558_12449
  • SCF06470.1
 55552 - 56298 (-) Phosphoglycolate phosphatase, HAD superfamily
copy AA seq
copy Nt seq
  • GA0070558_12450
  • SCF06476.1
 56300 - 57421 (-) Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily/HAD-superfamily hydrolase, subfamily IIB
copy AA seq
copy Nt seq
  • GA0070558_12451
  • SCF06487.1
 57642 - 58361 (-) Short-chain dehydrogenase
copy AA seq
copy Nt seq
  • GA0070558_12452
  • SCF06495.1
 58345 - 59076 (-) phosphoribosylaminoimidazole-succinocarboxamide synthase
copy AA seq
copy Nt seq
  • GA0070558_12453
  • SCF06506.1
 59099 - 59791 (-) probable phosphoglycerate mutase
copy AA seq
copy Nt seq
  • GA0070558_12454
  • SCF06515.1
 59781 - 61004 (-) adenosylhomocysteinase
copy AA seq
copy Nt seq
  • GA0070558_12455
  • SCF06525.1
 61001 - 62269 (-) adenosylhomocysteinase
copy AA seq
copy Nt seq
  • GA0070558_12456
  • SCF06535.1
 62266 - 63084 (-) methylthioadenosine phosphorylase
copy AA seq
copy Nt seq
  • GA0070558_12457
  • SCF06541.1
 63146 - 64570 (-) Phosphomannomutase
copy AA seq
copy Nt seq
  • GA0070558_12458
  • SCF06555.1
 64588 - 65841 (-) adenosylhomocysteinase
copy AA seq
copy Nt seq
  • GA0070558_12459
  • SCF06559.1
 65838 - 66872 (-) ribokinase
copy AA seq
copy Nt seq
  • GA0070558_12460
  • SCF06566.1
 66869 - 67288 (-) Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family
copy AA seq
copy Nt seq
  • GA0070558_12461
  • SCF06575.1
 67285 - 68034 (-) 3-oxoacyl-[acyl-carrier protein] reductase
copy AA seq
copy Nt seq
  • GA0070558_12462
  • SCF06581.1
 68027 - 68677 (-) DJ-1/PfpI family protein
copy AA seq
copy Nt seq
  • GA0070558_12463
  • SCF06587.1
 68674 - 69768 (-) myo-inositol-1-phosphate synthase
copy AA seq
copy Nt seq
  • GA0070558_12464
  • SCF06598.1
 69904 - 70908 (-) Predicted dehydrogenase
copy AA seq
copy Nt seq
  • GA0070558_12465
  • SCF06606.1
 71275 - 71937 (+) ATP phosphoribosyltransferase
copy AA seq
copy Nt seq
  • GA0070558_12466
  • SCF06618.1
 71958 - 73439 (-) adenosylhomocysteinase
copy AA seq
copy Nt seq
  • GA0070558_12467
  • SCF06629.1
 73641 - 74294 (-) Nucleoside-diphosphate-sugar epimerase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Entry added
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added chemical structures for compounds: coformycin.
  • Added NPAtlas links to compounds: coformycin.
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.