BGC0002438 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002438 (Pithomyces chartarum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	51,164	sporidesmin A	other:other	100%

BGC0002438 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 1 - 51,164 nt. (total: 51,164 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 51,165
Label		BGC0002438

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002438	0.77	Alkaloid	sporidesmin A	Pithomyces chartarum
BGC0000677	0.30	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000457	0.29	NRP	vicibactin	Rhizobium etli CFN 42
BGC0002226	0.27	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0000688	0.26	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0002208	0.24	NRP	oxepinamide F	Aspergillus ustus
BGC0001833	0.22	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001128	0.22	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286	0.22	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135	0.22	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002438	1.00	Alkaloid	sporidesmin A	Pithomyces chartarum
BGC0002608	0.71	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0002321	0.64	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001989	0.64	Other	pulcherrimin	Kluyveromyces lactis
BGC0000677	0.64	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000457	0.63	NRP	vicibactin	Rhizobium etli CFN 42
BGC0002226	0.60	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0000688	0.60	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0002208	0.57	NRP	oxepinamide F	Aspergillus ustus
BGC0002746	0.56	RiPP	dendrothelin A	Dendrothele bispora CBS 962.96

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 15413 - 51164:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

Spd17

Search NORINE for peptide: strict or relaxed

AMP-binding (12..408): Trp

nrpys: Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAGVVGACAK
Nearest Stachelhaus code(s):: Trp DAGIVGACAK (82% 8Å match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (1045..1433): X

nrpys: Gly, Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQMHAIVVK
Nearest Stachelhaus code(s):: Pro DVQYVAHVVK (53% 8Å match)
Stachelhaus code match:: 70% (weak)