BGC0002439: diastaphenazine biosynthetic gene cluster from Streptomyces diastaticus
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Location: 1 - 24,052 nt. (total: 24,052 nt).
This entry is originally from NCBI GenBank MK685983.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002439
Short description diastaphenazine biosynthetic gene cluster from Streptomyces diastaticus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
MK685983.1
1 - 24052
via Knock-out studies, Heterologous expression
Compounds
  • diastaphenazine
  • izumiphenazine C
Species Streptomyces diastaticus [taxonomy]
References
Chemical products information
diastaphenazine Evidence:
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Chemical database entries
NPAtlas
izumiphenazine C Evidence:
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Chemical database entries
NPAtlas
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QJS40186.1
  • dap1
 1 - 2103 (-) Para-aminobenzoate synthase
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    • QJS40187.1
    • dap2
    		 2088 - 2819 (-) methyltransferase
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      • QJS40188.1
      • dapR
      		 3059 - 4999 (+) Transcriptional regulator
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        • QJS40189.1
        • dap4
        		 4975 - 6192 (-) Transposase
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          • QJS40190.1
          • dap5
          		 6393 - 6752 (-) Cyclase
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            • QJS40191.1
            • dapS
            		 6749 - 8005 (-) PhzS
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              • QJS40192.1
              • dapG
              		 8019 - 8678 (-) Phenazine biosynthesis protein PhzG
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                • QJS40193.1
                • dapF
                		 8694 - 9530 (-) Phenazine biosynthesis protein PhzF
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                  • QJS40194.1
                  • dap9
                  		 9585 - 9914 (-) hypothetical protein
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                    • QJS40195.1
                    • dapB
                    		 9914 - 10402 (-) Phenazine biosynthesis protein PhzB
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                      • QJS40196.1
                      • dapC
                      		 10656 - 11828 (+) 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase
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                        • QJS40197.1
                        • dapD
                        		 11870 - 12529 (+) Isochorismatase
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                          • QJS40198.1
                          • dapE
                          		 12526 - 14415 (+) Phenazine biosynthesis protein PhzE
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                            • QJS40199.1
                            • aroA
                            		 14412 - 15659 (+) 5-enolpyruvyl-shikimate-3-phosphate synthase
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                              • QJS40200.1
                              • dap15
                              		 15656 - 16876 (+) Salicylate hydroxylase
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                                • QJS40201.1
                                • aroC
                                		 16873 - 18057 (+) Chorismate synthase
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                                  • QJS40202.1
                                  • aroEK
                                  		 18054 - 19406 (+) Bifunctional shikimate-5-dehydrogenas/ Shikimate kinase
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                                    • QJS40203.1
                                    • aroB
                                    		 19403 - 20539 (+) 3-dehydroquinate synthase
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                                      • QJS40204.1
                                      • dap19
                                      		 20561 - 22648 (+) Transketolase
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                                        • QJS40205.1
                                        • dap20
                                        		 22820 - 24052 (-) Methyltransferase
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-10-07
                                          Added chemical structures for compounds: diastaphenazine.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-10-07
                                          Added NPAtlas links to compounds: diastaphenazine.
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Entry added
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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