BGC0002443 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002443 (Streptomyces olivaceus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	PKS-like	1	32,300	mycemycin C/mycemycin A/mycemycin B	PKS	100%

BGC0002443 - Region 1 - PKS-like

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Location: 1 - 32,300 nt. (total: 32,300 nt) Show pHMM detection rules used

Region on contig edge.

PKS-like: (t2pks2 or ksIII)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 32,301
Label		BGC0002443

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002443	1.00	Polyketide	mycemycin C, mycemycin A, mycemycin B	Streptomyces olivaceus
BGC0000924	0.33	Other	pyrrolnitrin	Pseudomonas chlororaphis
BGC0002476	0.30	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000343	0.27	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.26	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001444	0.26	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0001592	0.26	Other	ferroverdin, bagremycin	Streptomyces lunaelactis
BGC0000662	0.25	Terpene	grixazone A	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001075	0.25	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0002473	0.24	NRP	propanochelin, butanochelin, pentanochelin	Acinetobacter bouvetii DSM 14964 = CIP 107468

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002443	1.00	Polyketide	mycemycin C, mycemycin A, mycemycin B	Streptomyces olivaceus
BGC0000924	0.66	Other	pyrrolnitrin	Pseudomonas chlororaphis
BGC0002476	0.64	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000343	0.60	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.60	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001444	0.60	Other (shikimate derived)	caboxamycin	Streptomyces sp. NTK 937
BGC0001592	0.59	Other	ferroverdin, bagremycin	Streptomyces lunaelactis
BGC0000662	0.59	Terpene	grixazone A	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001075	0.58	Terpene, Polyketide	aurachin RE	Rhodococcus erythropolis
BGC0002473	0.58	NRP	propanochelin, butanochelin, pentanochelin	Acinetobacter bouvetii DSM 14964 = CIP 107468

Similar known gene clusters from MIBiG 4.0

NRPS/PKS substrates

NRPS/PKS substrate predictions

mymF

AMP-binding (31..439): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PWPSQGVLCK
Nearest Stachelhaus code(s):: Hpa TWPSQGVLCK (82% 8Å match)
Stachelhaus code match:: 90% (moderate)