BGC0002448: Q6402A biosynthetic gene cluster from Streptomyces violaceusniger
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 59,505 nt. (total: 59,505 nt).
This entry is originally from NCBI GenBank LC535008.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002448
Short description Q6402A biosynthetic gene cluster from Streptomyces violaceusniger
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
LC535008.1
1 - 59505
via Heterologous expression
Compounds
  • Q6402A
Species Streptomyces violaceusniger [taxonomy]
References
Chemical products information
Q6402A Evidence:
Copy SMILES
C50H61N7O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BCD33669.1
  • orf1
 1 - 144 (+) SGNH/GDSL hydrolase family protein
    copy AA seq
    copy Nt seq
    • BCD33670.1
    • orf2
    		 461 - 970 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • BCD33671.1
      • orf3
      		 1732 - 1902 (-) hypothetical protein
        copy AA seq
        copy Nt seq
        • BCD33672.1
        • orf4
        		 2045 - 3271 (+) pyroglutamyl peptidase
          copy AA seq
          copy Nt seq
          • BCD33673.1
          • orf5
          		 3338 - 4057 (-) hypothetical protein
            copy AA seq
            copy Nt seq
            • BCD33674.1
            • orf6
            		 4201 - 5109 (-) virginiamycin B lyase
              copy AA seq
              copy Nt seq
              • BCD33675.1
              • orf7
              		 5314 - 5868 (-) cell surface receptor IPT/TIG domain-containing protein
                copy AA seq
                copy Nt seq
                • BCD33676.1
                • orf8
                		 6190 - 7209 (-) NADP-dependent oxidoreductase
                  copy AA seq
                  copy Nt seq
                  • BCD33677.1
                  • orf9
                  		 7292 - 7738 (+) putative MarR-family transcriptional regulator
                    copy AA seq
                    copy Nt seq
                    • BCD33678.1
                    • orf10
                    		 7766 - 8512 (-) hypothetical protein
                      copy AA seq
                      copy Nt seq
                      • BCD33679.1
                      • orf11
                      		 8713 - 9360 (+) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • BCD33680.1
                        • orf12
                        		 9335 - 9760 (-) OsmC family protein
                          copy AA seq
                          copy Nt seq
                          • BCD33681.1
                          • orf13
                          		 9827 - 10492 (-) histidine phosphatase superfamily
                            copy AA seq
                            copy Nt seq
                            • BCD33682.1
                            • orf14
                            		 10485 - 10907 (-) thioredoxin
                              copy AA seq
                              copy Nt seq
                              • BCD33683.1
                              • orf15
                              		 11019 - 12584 (-) VCBS repeat-containing protein
                                copy AA seq
                                copy Nt seq
                                • BCD33684.1
                                • orf16
                                		 12810 - 13694 (+) AraC family transcriptional regulator
                                  copy AA seq
                                  copy Nt seq
                                  • BCD33685.1
                                  • orf17
                                  		 13800 - 14261 (-) ABC transporter permease
                                    copy AA seq
                                    copy Nt seq
                                    • BCD33686.1
                                    • orf18
                                    		 14340 - 14993 (+) bacterial regulatory proteins, luxR family
                                      copy AA seq
                                      copy Nt seq
                                      • BCD33687.1
                                      • orf19
                                      		 15237 - 15491 (+) hypothetical protein
                                        copy AA seq
                                        copy Nt seq
                                        • BCD33688.1
                                        • orf20
                                        		 15541 - 15900 (-) hypothetical protein
                                          copy AA seq
                                          copy Nt seq
                                          • BCD33689.1
                                          • orf21
                                          		 16003 - 17106 (-) c-type cytochrome biogenesis protein CcsB
                                            copy AA seq
                                            copy Nt seq
                                            • BCD33690.1
                                            • orf22
                                            		 17779 - 36336 (+) non-ribosomal peptide synthetase
                                              copy AA seq
                                              copy Nt seq
                                              • BCD33691.1
                                              • orf23
                                              		 36333 - 40271 (+) non-ribosomal peptide synthetase
                                                copy AA seq
                                                copy Nt seq
                                                • BCD33692.1
                                                • orf24
                                                		 40268 - 40486 (+) putative MbtH-like protein
                                                  copy AA seq
                                                  copy Nt seq
                                                  • BCD33693.1
                                                  • orf25
                                                  		 40479 - 41915 (+) tryptophan 2,3-dioxygenase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • BCD33694.1
                                                    • orf26
                                                    		 41990 - 43096 (-) FMN-dependent dehydrogenase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • BCD33695.1
                                                      • orf27
                                                      		 43093 - 44166 (-) 4-hydroxyphenylpyruvate dioxygenase
                                                        copy AA seq
                                                        copy Nt seq
                                                        • BCD33696.1
                                                        • orf28
                                                        		 44230 - 45558 (-) (S)-3,5-dihydroxyphenylglycine transaminase
                                                          copy AA seq
                                                          copy Nt seq
                                                          • BCD33697.1
                                                          • orf29
                                                          		 45864 - 47786 (+) B12-binding domain-containing radical SAM protein
                                                            copy AA seq
                                                            copy Nt seq
                                                            • BCD33698.1
                                                            • orf30
                                                            		 47786 - 48997 (+) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
                                                              copy AA seq
                                                              copy Nt seq
                                                              • BCD33699.1
                                                              • orf31
                                                              		 49711 - 50124 (+) glyoxalase
                                                                copy AA seq
                                                                copy Nt seq
                                                                • BCD33700.1
                                                                • orf32
                                                                		 50533 - 50820 (+) transposase
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • BCD33701.1
                                                                  • orf33
                                                                  		 50775 - 52121 (+) ISL3 family transposase
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • BCD33702.1
                                                                    • orf34
                                                                    		 52236 - 53291 (+) zinc ribbon domain-containing protein
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • BCD33703.1
                                                                      • orf35
                                                                      		 53444 - 53797 (-) hypothetical protein
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • BCD33704.1
                                                                        • orf36
                                                                        		 54099 - 55226 (-) hypothetical protein
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • BCD33705.1
                                                                          • orf37
                                                                          		 55239 - 55445 (-) hypothetical protein
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            • BCD33706.1
                                                                            • orf38
                                                                            		 56002 - 57075 (+) hypothetical protein
                                                                              copy AA seq
                                                                              copy Nt seq
                                                                              • BCD33707.1
                                                                              • orf39
                                                                              		 57439 - 57669 (+) DUF3137 domain-containing protein
                                                                                copy AA seq
                                                                                copy Nt seq
                                                                                • BCD33708.1
                                                                                • orf40
                                                                                		 57666 - 59240 (+) site-specific integrase
                                                                                  copy AA seq
                                                                                  copy Nt seq
                                                                                  Biosynthesis information
                                                                                  Annotation changelog

                                                                                  Entry version: next

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2024-03-19
                                                                                  MIBiG v4 annotathon
                                                                                  • (ID: BYMOQMBRAB25QU6RBYAHVZZ5)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                  Entry version: 1

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2022-09-15
                                                                                  Entry added
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  Detailed domain annotation
                                                                                  Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                                                  A domain glossary is available here, and an explanation of the visualisation is available here.
                                                                                  Selected features only
                                                                                  Show module domains
                                                                                  Similar known gene clusters from MIBiG 4.0
                                                                                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                                  Click on reference genes to show details of similarities to genes within the current region.
                                                                                  Click on an accession to open that entry in the MiBIG database.