BGC0002452: leucomycin biosynthetic gene cluster from Streptomyces kitasatoensis
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Location: 1 - 96,795 nt. (total: 96,795 nt).
This entry is originally from NCBI GenBank LC496468.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002452
Short description leucomycin biosynthetic gene cluster from Streptomyces kitasatoensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
LC496468.1
via
Compounds
  • leucomycin
Species Streptomyces kitasatoensis [taxonomy]
References
Chemical products information
leucomycin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBM96620.1
 111 - 1598 (-) methyltransferase
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    • BBM96621.1
    		 1703 - 2611 (-) homocysteine S-methyltransferase
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      • BBM96622.1
      		 2667 - 3590 (-) monooxygenase
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        • BBM96623.1
        		 3838 - 4032 (+) hypothetical protein
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          • BBM96624.1
          		 4044 - 4502 (-) hypotheticl protein
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            • BBM96625.1
            		 4698 - 5117 (-) hypothetical protein
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              • BBM96626.1
              		 5092 - 6318 (-) bldA-regulated nucleotide binding protein
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                • BBM96627.1
                		 6343 - 6747 (-) hypothetical protein
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                  • BBM96628.1
                  		 6876 - 7484 (-) TetR-family transcriptional regulator
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                    • BBM96629.1
                    		 7607 - 7792 (+) hypothetical protein
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                      • BBM96630.1
                      • macR
                      		 7867 - 8796 (-) 23S rRNA methyltransferase
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                        • BBM96631.1
                        • lcmN
                        		 9330 - 10985 (+) ABC transporter ATP-binding protein
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                          • BBM96632.1
                          • lcmK
                          		 11162 - 12358 (+) 3-O-acetyltransferase
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                            • BBM96633.1
                            • lcmH
                            		 12402 - 13067 (+) O-methyltransferase
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                              • BBM96634.1
                              • lcmBIII
                              		 13134 - 14408 (-) mycaminosyl transferase
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                                • BBM96635.1
                                • lcmBII
                                		 14624 - 15853 (-) NDP-hexose-3,4-isomerase
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                                  • BBM96636.1
                                  • lcmBI
                                  		 16021 - 16734 (-) NDP-aminohexose N-dimethyltransferase
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                                    • BBM96637.1
                                    • lcmA5
                                    		 16734 - 22295 (-) modular polyketide synthase
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                                      • BBM96638.1
                                      • lcmA4
                                      		 22368 - 27035 (-) modular polyketide synthase
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                                        • BBM96639.1
                                        • lcmA3
                                        		 27094 - 39249 (-) modular polyketide synthase
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                                          • BBM96640.1
                                          • lcmA2
                                          		 39356 - 45229 (-) modular polyketide synthase
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                                            • BBM96641.1
                                            • lcmA1
                                            		 45330 - 58454 (-) modular polyketide synthase
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                                              • BBM96642.1
                                              • lcmJ
                                              		 58613 - 59671 (-) ketoreductase
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                                                • BBM96643.1
                                                • lcmI
                                                		 60093 - 61301 (+) cytochrome P450 hydroxylase
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                                                  • BBM96644.1
                                                  • lcmCI
                                                  		 61292 - 61849 (+) NDP-hexose isomerase
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                                                    • BBM96645.1
                                                    • lcmCII
                                                    		 61846 - 63012 (+) NDP-hexose aminotransferase
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                                                      • BBM96646.1
                                                      • lcmCIII
                                                      		 63009 - 63917 (+) glucose-1-phosphate thymidyltransferase
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                                                        • BBM96647.1
                                                        • lcmCIV
                                                        		 63901 - 64905 (+) dTDP-glucose 4,6-dehydratase
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                                                          • BBM96648.1
                                                          • lcmCV
                                                          		 64981 - 66411 (+) NDP-hexose 2,3-dehydratase
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                                                            • BBM96649.1
                                                            • lcmL
                                                            		 66662 - 67771 (-) 4''-O-acyltransferase
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                                                              • BBM96650.1
                                                              • lcmRI
                                                              		 68207 - 69361 (+) regulator for expression of lcm cluster
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                                                                • BBM96651.1
                                                                • lcmRII
                                                                		 69406 - 71358 (-) CdaR-family transcriptional regulator
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                                                                  • BBM96652.1
                                                                  • lcmCVI
                                                                  		 71556 - 72638 (-) transaldolase
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                                                                    • BBM96653.1
                                                                    • lcmCVII
                                                                    		 72680 - 73288 (-) NDP-hexose 3,5-epimerase
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                                                                      • BBM96654.1
                                                                      • lcmCVIII
                                                                      		 73510 - 74724 (-) mycarosyl transferase
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                                                                        • BBM96655.1
                                                                        • lcmD
                                                                        		 75051 - 75941 (+) 3-hydroxyacyl-CoA dehydrogenase
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                                                                          • BBM96656.1
                                                                          • lcmE
                                                                          		 75938 - 76255 (+) acyl carrier protein
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                                                                            • BBM96657.1
                                                                            • lcmF
                                                                            		 76248 - 77375 (+) acyl-CoA dehydrogenase
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                                                                              • BBM96658.1
                                                                              • lcmG
                                                                              		 77423 - 78523 (+) hydrolase
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                                                                                • BBM96659.1
                                                                                • lcmCIX
                                                                                		 78520 - 79752 (+) NDP-hexose 3-C-methyltransferase
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                                                                                  • BBM96660.1
                                                                                  • lcmCX
                                                                                  		 79866 - 80864 (-) dTDP-4-keto-6-deoxy-L-hexose 2,3-reductase
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                                                                                    • BBM96661.1
                                                                                    • lcmCXI
                                                                                    		 80861 - 81865 (-) dTDP-4-keto-6-deoxy-L-hexose 4-reductase
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                                                                                      • BBM96662.1
                                                                                      		 82242 - 82610 (+) isomerase
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                                                                                        • BBM96663.1
                                                                                        		 82600 - 83646 (-) DNA-binding protein
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                                                                                          • BBM96664.1
                                                                                          		 83720 - 86323 (-) hypothetical protein
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                                                                                            • BBM96665.1
                                                                                            		 86541 - 87008 (+) transcriptional regulator
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                                                                                              • BBM96666.1
                                                                                              		 87096 - 89003 (-) sulfate adenylyltransferase, large subunit
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                                                                                                • BBM96667.1
                                                                                                		 89003 - 89938 (-) sulfate adenylyltransferase, small subunit
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                                                                                                  • BBM96668.1
                                                                                                  		 89935 - 90795 (-) inositol monophosphatase
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                                                                                                    • BBM96669.1
                                                                                                    		 91080 - 91871 (+) thioesterase
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                                                                                                      • BBM96670.1
                                                                                                      		 91880 - 92926 (+) hypothetical protein
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                                                                                                        Biosynthesis information
                                                                                                        Annotation changelog

                                                                                                        Entry version: 1

                                                                                                        Date
                                                                                                        Changes
                                                                                                        Submitters
                                                                                                        Reviewers
                                                                                                        2022-09-15
                                                                                                        Entry added
                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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