LOCUS       BGC0002464             10571 bp    DNA     linear   CON 25-MAR-2023
DEFINITION  Bordetella pertussis Tohama I chromosome, complete genome.
ACCESSION   BGC0002464
VERSION     BGC0002464
KEYWORDS    .
SOURCE      Bordetella pertussis Tohama I
  ORGANISM  Bordetella pertussis Tohama I
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Alcaligenaceae; Bordetella.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP039022.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:46:28
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2597770
            Orig. end    :: 2608341
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1386
                     /EC_number="1.14.13.-"
                     /codon_start=1
                     /gene="alcA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 377.8;
                     E-value: 9.8e-115)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010926977.1"
                     /locus_tag="EQ877_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis hydroxylase AlcA"
                     /protein_id="WP_003814013.1"
                     /transl_table=11
                     /translation="MNREIYDFVAIGIGPFNLSLASLSAPLRGVRTLFLDKKSGFDWHP
                     GMLIETSTLQNPFLADLVSLADPRSEYSYLNYCKLTNRIYSYYMRENHYLSRAEYTRYC
                     QWVAARLPNLRFGCDVQGVLHDPESHSYLVTGQHTMSGQRFMFRCRKLVLGLGSQPYLP
                     ACCDRRAAPFIHSADYLRHKYELQGRASITIVGSGQSAAEVFHDLLRESGRHDYSLAWI
                     TRSPRFFQMENTKLTLELISPDYTEYFHDLPEARRQEILTQQNSLYKGINASLINQIYD
                     LLDEKVHDGDNRYTLLTNSELRACRYDPLQERFQLDFQHLDCDRPFSHATDGLVLATGY
                     SHEIPACINPIHDRIAWNADGSYRIGRNYAIDHEGSEIFVQNTGLLSHGVTNPDLGFCC
                     YRNSQILRELTGTEHYRIETRTALQEFSPPADGVLKHRPARRAERRPTVAARPLMDIHR
                     ATL"
     subregion       1..10571
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..10571
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1386
                     /gene="alcA"
                     /locus_tag="EQ877_RS12490"
     gene            1405..2010
                     /gene="alcB"
                     /locus_tag="EQ877_RS12495"
     CDS             1405..2010
                     /codon_start=1
                     /gene="alcB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     122.1; E-value: 6.5e-37)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003814014.1"
                     /locus_tag="EQ877_RS12495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis acetyltransferase AlcB"
                     /protein_id="WP_003814014.1"
                     /transl_table=11
                     /translation="MMTMMATFLDVIDQKARSHYDEGKGLALRSLDPEADAAQLQQWFS
                     MDYARFWSMQDSSVHQVRDFYTALCSSGHAGAWLGLHHGRAAFLVECYDPARDQVGEHY
                     CVRPGDLGMHLLIAPPTEHIPGFSRAVFALVMRFMFDRLHAARVVVEPDVNNTKIHALN
                     LSMGFVYAGLARFREKTASLAFCTRAQFEQAQRQELTQ"
     gene            2007..3863
                     /gene="alcC"
                     /locus_tag="EQ877_RS12500"
     CDS             2007..3863
                     /codon_start=1
                     /gene="alcC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010926978.1"
                     /locus_tag="EQ877_RS12500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis protein AlcC"
                     /protein_id="WP_010930939.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.2e-79, bitscore:
                     256.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTTPPHPAEIVAHLQPEIWNKVNRLLVRKAISEYAHEWLLEPQ
                     RLGSGETPGFERFRLTLADGAQYDFDAQVMAMRHWRIPPESIVKTVAGVPAPLDALQFV
                     IEIRDKLGLPVDRLPIYMDEITSTLHGSAYKHGRTTLGAAALARADYQTIETSMIEGHP
                     SFVANNGRLGFDAEDYHGYAPEAATPVRLMWLAVHKDNAHFSCLSDMDYDSLMSEELGE
                     SAVTDFAARLREQGLHPADYYFMPAHPWQWFNKLSLAFAPYVAQRKIVCLGYGEEQYLA
                     QQSIRTFFNISRPGKRYVKTSLSILNMGFMRGLSPYYMAGTPAINEYIHDLISADPWLR
                     ANGFRILREVASMGFRNYYYEAAIDTDTPYKKMFSALWRENPLTLIAPGQNLMTMAALL
                     HVDPQGRALLPELIQASGLDAGTWLERYVDAYLTPLIHCFYAHDLVFMPHGENVILVIQ
                     DGVPVRAFMKDIAEESSILNPQVRLPQAAQRLAADVPEAYKLLTIFVDVFEGYFRHLTQ
                     ILVETELMPEHDFWRLVAGRIAAYQQAHPQRLDKYRRYDLFAPDMIHSCLNRLQLANNL
                     QMVNLADPIGSFQMAPNLPNPIACFRPSWLGSGEALQTLTAA"
     gene            3860..4660
                     /gene="alcD"
                     /locus_tag="EQ877_RS12505"
     CDS             3860..4660
                     /codon_start=1
                     /gene="alcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003814016.1"
                     /locus_tag="EQ877_RS12505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis protein AlcD"
                     /protein_id="WP_003814016.1"
                     /transl_table=11
                     /translation="MSWDIAAQTGAGVAQDINRTACSDLDALLALAGSLVPGLDGRIGP
                     VSGDIRPGADNRATLRTLQDWWRLRHPEAGSHYLALRCWGLLIWQPIYLGVIAVHCSDI
                     APDLDRLGQPVRDGFIAGYILERHEPLRGCLEQRKQAVAAQLRRICATYFRELSQLLRL
                     SPRAAACMQADCVLSALLAARANEDKAAVAWAHEQAADWLDRLGIAGHSGYLVYARAGR
                     PVLALDRQVCCHHFRRHDGDYCSTCPKLPPAERIARIEADEAAA"
     gene            4675..5868
                     /gene="alcE"
                     /locus_tag="EQ877_RS12510"
     CDS             4675..5868
                     /codon_start=1
                     /gene="alcE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005013753.1"
                     /locus_tag="EQ877_RS12510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis hydroxylase AlcE"
                     /protein_id="WP_005013753.1"
                     /transl_table=11
                     /translation="MTDIASLAQLQQALSPLHARAYFDEALFVREQEILFRQSALYVGH
                     EKSVPEPGDWRRLPQDDGSRILVRNGNEVALLSNVCRHRQAVMLGPIAGGEAMKGNLSV
                     TGGNIVCPLHRWTYDGQGRILGAPHFPSTPCLNLSRFPLHNCHGLLFEGPRDPLKDLDV
                     LFRRPEFDFSDYVLDHVEVHRCNYNWKTFIEVYLEDYHVGPFHPGLGRFVTCADLSWEF
                     GAQYSLQKVGVHDSLEQPGTEVYRGWHDNLMRYRGGRTPDFGAIWVTYFPTHMIELYPH
                     VLVLSTLYPKGPQETLNIAEFYYPEEIALFERDFVQAQRAAYMETAVEDDEIGERMDAG
                     RLALLRRGVSDSGPYQSPMEDGMLHFHEWYLSNMGEQLGDSAAPHVASTQRPMPFRS"
     gene            5936..6910
                     /gene="alcR"
                     /locus_tag="EQ877_RS12515"
     CDS             5936..6910
                     /codon_start=1
                     /gene="alcR"
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 76.4; E-value: 3.5e-23)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010926980.1"
                     /locus_tag="EQ877_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin siderophore biosynthesis
                     transcriptional regulator AlcR"
                     /protein_id="WP_003814017.1"
                     /transl_table=11
                     /translation="MTQPTLPPPPRTRFTVSDFNRMGGSVGFNYRLPGQEGGGAGIENL
                     CIAEGRVEECEIRPGITLIVSDVHVYHHYESTSVMTPRFSAIVMLQGQARARLDKQDDV
                     RLAAQSGLNALYGDTVAMTGVHPAGQRLRSVNLSVTAPEAADDEYTSEIIWKLMQSSAP
                     RLRRWPVPHHLLLSIEHLLECDWDQPLRNMVREGVGTQLLAHALAALQHAPVTHRGLTQ
                     RDRQLLERVRERLHEAPGEDHTLDDLARLACMSPSTLRAKFHAVYHRSVFSWLRERRLE
                     VAREQLARGWSVQQAAHFVGYRHATNFATAFRERYGVAPSQLG"
     gene            7033..8256
                     /gene="bcr"
                     /gene_synonym="alcS"
                     /locus_tag="EQ877_RS12520"
     CDS             7033..8256
                     /codon_start=1
                     /gene="bcr"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 91.1; E-value:
                     8.6e-28)"
                     /gene_kind="transport"
                     /gene_synonym="alcS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010926981.1"
                     /locus_tag="EQ877_RS12520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin export MFS transporter Bcr"
                     /protein_id="WP_010930940.1"
                     /transl_table=11
                     /translation="MSRAASAPSYSLMMVMLGLLSCVAPASIDAYLPAFGALQREFGVP
                     QETVQLTLGVYMFCYAAMLLLHGTLSDSLGRRRVVLGALGFYVWGALLATAAPGFGWLL
                     AARALQGLSAGAGVVVGQAIIRDCYQGAAAQRSMSYLILVFNLSPALAPVIGGQLAVHH
                     GWRSIFFMLGLLAATALTLCAWRLPETLAPAKRQTLSLRGLAAGYREVLRNGNFTAPGL
                     AFSLVFAAQGLLIGAAPDFIANVLDLPETNFAYLFVPLVAGAMTGAAIAARHAGRWRDT
                     RIIGLAYLLMNGSCLAYAIYFWTALSPALPWAVLPPALFTCGLAMSVPAMTLHILESVP
                     ALSGTGASVLGFMQMLAFSIASGWGVPLTYGQPSVLALAMLACVTASALAWAWLQHLSR
                     ISAKVQAR"
     gene            8367..10571
                     /gene="fauA"
                     /locus_tag="EQ877_RS12525"
     CDS             8367..10571
                     /codon_start=1
                     /gene="fauA"
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     577.9; E-value: 5.1e-175)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010930941.1"
                     /locus_tag="EQ877_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent alcaligin siderophore receptor
                     FauA"
                     /protein_id="WP_010930941.1"
                     /transl_table=11
                     /translation="MPDPAHFSPAHSRRLRFFAHVLHLLGALFTQHALAQEARTGNDIA
                     QLPAISVTGREISDLTEGTNAYTTEAMSTATGLTLSPRETPQSVSVVTRQQIEDQGLTD
                     TGAILATAPGISVTRSDSNRYSFSARGFTIDNFQFDGLVSPILSQWNYGSTDMDAAIYD
                     HVEIVRGATGLMTGSGNPSAAVNFVRKRPLREFAATFNASVGSWDYVRGDADISVPITE
                     DGRIRSRLVAAYSQGDSYVHFLDTRRRTFYGVVSADLTPDTVLTTSVEYQHNHSNGFGS
                     GFPLFYSDGSRTDFNRSVANNAPWARQDTEATTYFVDLTHRFTNDWKLRAAYSHTDGRY
                     LMKHVYRGGYPDRHTGIIAAPPAFSNYDGNLDRDDIHFSLSAPFEAFGLRHEVALGWMS
                     IDNHSDIQRYAMVGPAPAIGSFFDWRRAHIQEPSWADTLSPADDVRTKQTGAYLVGRFA
                     LAEPLHLIVGDRWSDWKTKQMYFGSRREYRIKNQFTPYAGLTYDINDTYTAYASYTEIF
                     QPQNARDTSGGILPPIKSKSYELGLKAAYLEGRLNTSAALFQTRQDNLAQVIPGSSIPG
                     FPNMQASRAASGAKVEGIDLEASGQILPDWNIGASYTHFTTKDASGNPINTNHPRSLFK
                     LYTTYRLPGALHRLTVGGGVDWQSRMYQAAASPRGNVEVEQDSYALVSLMARFDFNKKL
                     SATLNVNNLFDKKYYDQIGFYSQGWWGAPRNVMLNLRAQY"
ORIGIN
        1 atgaatcgtg aaatctatga cttcgtggct atcggtatcg gacctttcaa tctcagcctg
       61 gcgagcctgt ctgcgccctt gcgaggcgtg cgcacgctct tcctggacaa gaaatccggc
      121 tttgattggc atccaggcat gctgatcgag acgtccactc tgcaaaaccc ttttctcgcc
      181 gatctggtca gtttggccga cccacgcagc gaatatagct atctgaacta ttgcaaactc
      241 accaaccgca tttattccta ctacatgcgc gagaaccatt acctgagccg cgccgagtac
      301 acccgctatt gccaatgggt agctgcacgc ttgccgaacc tgcgtttcgg ctgcgatgta
      361 cagggcgtac tgcacgatcc cgaaagccac agctatctcg tcaccggcca acacaccatg
      421 tccggccagc ggttcatgtt ccgctgccgc aagctggtcc tgggtcttgg ttcccagccc
      481 tatctgccag cgtgctgcga tcgacgtgcc gcgcccttca tccatagcgc ggactatctg
      541 cgccataaat acgaactcca gggccgcgcg tcaatcacca tagtgggcag cggacaaagc
      601 gcggccgaag tgttccatga tctgctccgt gagagcgggc gacatgatta cagtctggcc
      661 tggatcactc gctctccgcg ctttttccag atggagaaca caaaactcac gctggagctg
      721 atatcgccgg attacaccga atatttccat gatctgcccg aggcacgccg ccaggagatc
      781 ctgactcaac agaacagtct gtacaaaggc atcaatgcct cgctgatcaa ccagatctac
      841 gatcttctcg acgagaaggt ccatgatggc gacaaccgct atacgcttct gaccaactcc
      901 gaactacgcg cctgccgcta cgacccgctg caggaacgct ttcagctgga ctttcagcat
      961 ctcgattgcg accgcccttt tagccacgcc accgacggac tggtcctggc cacaggctat
     1021 tctcatgaga tcccggcctg catcaatccc attcacgacc gaattgcctg gaatgccgac
     1081 ggtagctacc gcatcggacg taattacgcc attgaccacg agggcagcga gatcttcgtg
     1141 cagaacaccg gtttgctcag ccatggagtg acgaatccgg atctgggctt ctgctgctat
     1201 cgcaactcac agatcctgcg tgaactgacc ggcacggaac attaccgcat cgagacacga
     1261 accgccttgc aggagttctc tccaccagca gacggcgtgc tcaagcaccg tccggcccgg
     1321 cgagccgaac ggaggcccac ggttgcagcc cgacccttga tggacatcca ccgcgccaca
     1381 ctctgaggct gccaaggaag cgcgatgatg acgatgatgg caacgttcct ggacgtgatc
     1441 gaccaaaaag cccgctccca ctatgacgaa ggcaagggat tggcgttacg ttcgctcgac
     1501 cccgaggcgg acgcagccca gctgcagcaa tggttttcca tggactatgc ccgcttctgg
     1561 tccatgcaag actctagcgt gcaccaggtg cgcgacttct acactgcgtt gtgctccagt
     1621 ggacacgccg gagcctggct gggcctgcac catggccgtg cggcctttct ggtggaatgc
     1681 tatgacccgg ctcgcgacca agtcggcgag cactactgcg tgcgcccagg cgacctgggc
     1741 atgcatcttc tcatcgcccc cccgaccgag cacattcccg gtttcagccg tgcggtgttc
     1801 gcgctcgtca tgcgcttcat gttcgaccgc ctccatgcgg cccgtgtcgt cgtggaaccc
     1861 gacgtgaaca acaccaagat ccatgcattg aatctatcca tgggcttcgt ctatgccggg
     1921 ctggcgcgct ttcgggaaaa gacggcaagt cttgccttct gcacgcgcgc ccaattcgag
     1981 caagcccaac gccaggagtt gacgcaatga gccgcaccac ccctcctcat cccgccgaga
     2041 tcgttgctca tctgcagccg gaaatctgga acaaggtcaa tcgcctgctg gtgcgcaagg
     2101 cgatatccga atatgcacat gagtggctgc tcgaacctca gcgactcggt tcgggcgaaa
     2161 cgccgggatt tgaacgcttt cgcctgacac tggctgacgg cgcgcaatat gactttgacg
     2221 ctcaggtcat ggccatgcgc cattggcgta ttccgcctga atccatcgta aagaccgtgg
     2281 ccggggttcc ggcgccgctg gatgccctgc agttcgtgat agagatccgg gacaaactcg
     2341 gcttgccggt ggaccgtctg cccatctata tggacgaaat caccagcact ctacacggca
     2401 gcgcctataa acatggccgg acgacgcttg gcgccgcggc attggcacga gccgactacc
     2461 agaccataga aacatcgatg atcgagggcc accccagctt cgtggccaac aatggccgcc
     2521 ttggctttga tgccgaggat taccatggct acgcgcccga agctgccacg ccggtgcgct
     2581 tgatgtggtt ggcggttcac aaggacaacg cgcatttttc ctgcttgtcc gacatggact
     2641 acgacagcct gatgagcgag gagttgggtg agtccgctgt aaccgatttc gccgcccgac
     2701 tgcgcgagca gggcctgcat cccgcggact actacttcat gcccgcccac ccatggcaat
     2761 ggttcaacaa gctgtccctg gcttttgccc cctacgtcgc ccagcgcaaa atcgtctgcc
     2821 tggggtacgg cgaggagcaa tacctcgctc agcagtccat ccgcaccttt ttcaacatca
     2881 gccgacccgg caagcgctat gtgaagacct cgctgtccat tctcaacatg ggattcatgc
     2941 gcggcctgtc accctactac atggcaggta cgccagccat caacgaatac atccatgacc
     3001 tgatatcggc cgatccgtgg ctgcgcgcca atggtttcag aattctgcgc gaagtcgcct
     3061 cgatgggctt tcgcaactac tactacgaag ccgccatcga tacggacaca ccgtacaaga
     3121 agatgttctc ggcgctttgg cgcgagaacc ccctgacgct gatcgctccc ggacaaaatc
     3181 tcatgaccat ggctgcgctg ctgcatgtgg acccacaagg ccgggctttg cttcccgaat
     3241 tgatacaggc ttcaggactg gatgcaggga cttggctgga gcgctatgtg gacgcttatc
     3301 tgactccact gatccattgt ttctatgctc atgacctggt tttcatgccg cacggtgaaa
     3361 acgtgattct cgtcatccag gatggcgtac ctgtgcgcgc cttcatgaag gacatcgcgg
     3421 aagagtcttc catcctcaat ccgcaggtca ggcttccgca ggcggctcag cgcctggccg
     3481 ccgatgtgcc ggaggcctat aagctgctga cgattttcgt ggatgtcttc gagggctatt
     3541 tccgccatct gacccagatc ctggttgaga cggaactgat gccggaacat gatttctggc
     3601 ggctagtggc tgggcgcatc gccgcttatc agcaagcgca tccgcaacgg ctcgacaagt
     3661 atcggcgcta cgacttgttt gcgcccgaca tgatccattc gtgcctgaac cgcctgcaat
     3721 tggccaacaa tctgcagatg gtcaacctgg ccgatcccat tggcagtttc caaatggccc
     3781 ccaatctgcc caaccctatc gcctgcttcc gtccgtcgtg gctgggtagc ggcgaagccc
     3841 tgcagacgct gacggccgca tgagctggga cattgccgcc cagaccggcg ccggcgtggc
     3901 ccaagacatc aatcggaccg cctgctcgga cctggatgct ctgctcgccc tggctggttc
     3961 cctggtgccc gggctcgatg gacgcatcgg tccggtctcc ggcgatatcc ggccgggcgc
     4021 cgacaatcgg gctacgctgc ggacgctgca agactggtgg cgcctgcgcc atcccgaagc
     4081 tggctcgcat tatctggcgc tacgttgctg gggcctgctg atctggcagc cgatttacct
     4141 gggtgtaatc gcggtgcatt gcagcgacat tgctccggat ctggatcgcc tcggccagcc
     4201 ggtgcgcgat ggtttcatcg cgggctacat tctcgaacgc cacgagccgt tacgcggttg
     4261 tctggaacag cgcaagcagg cagttgccgc tcagctacgc cggatctgcg cgacctattt
     4321 tcgggagctc tcccaactgt tgcgcctgag cccgcgcgcc gcggcgtgca tgcaggcgga
     4381 ctgcgtgcta tccgctctgc tagccgcccg tgccaatgag gacaaggccg ccgtggcctg
     4441 ggcgcatgag caggcggccg actggctgga tcgcctggga atcgccggcc acagcggcta
     4501 tctggtttat gcgcgcgccg gccggcccgt cctggcgctt gaccgccagg tctgctgcca
     4561 ccatttccgc cgccacgacg gcgactattg cagtacttgc cccaaattgc cccccgccga
     4621 gcgtatcgcg cgcatcgagg cggacgaggc ggcagcctga gtaaggagcc ggacatgacg
     4681 gatatcgcca gcctggcgca gttgcagcaa gcgctcagcc ctctgcacgc acgggcctat
     4741 tttgatgaag ccctcttcgt gcgagaacag gaaatcctgt tccgacaatc tgcgttatat
     4801 gtcgggcatg agaagagcgt gcccgagccg ggcgactggc gtcgcttgcc gcaggacgac
     4861 ggcagtcgca tcctcgtgcg caatggaaat gaagtggcac tgctgtcgaa tgtctgccgc
     4921 catcgccagg ccgtcatgct aggcccgatt gcaggcggcg aggccatgaa gggcaatctg
     4981 tcagtcacgg gaggcaacat cgtctgcccg ttgcaccgct ggacttacga cggccagggc
     5041 cggattctag gcgcccccca ctttcccagt acgccctgcc tgaatctgtc gcgcttcccc
     5101 ctgcataact gccatgggct actgttcgaa ggcccacgcg atccattgaa agacctcgac
     5161 gtgcttttcc gccgacccga attcgatttc tccgactatg tgctggacca cgtcgaagta
     5221 catcgatgca attacaactg gaagactttc atcgaagtct atctggagga ctatcacgtg
     5281 ggccctttcc atccgggcct tggacgcttt gtcacctgcg ccgacctgtc ctgggagttc
     5341 ggcgcgcaat acagtctcca gaaggtgggc gtgcacgact cactggaaca acccggtacc
     5401 gaggtctatc gcggctggca tgacaatctc atgcgctacc ggggcgggag gaccccggat
     5461 ttcggagcca tctgggtaac ctacttcccc acccacatga ttgagctcta cccgcatgtg
     5521 ctggtgctct cgacgctcta tcccaagggg ccgcaagaga ctttgaacat cgcggagttc
     5581 tactatccgg aggaaattgc gctgttcgag cgtgatttcg tacaggccca acgcgctgcc
     5641 tacatggaga cggcggtcga agacgatgaa atcggtgagc gcatggacgc cggacgcctg
     5701 gcgctgctgc gccgcggcgt ttccgacagc ggcccctatc aatcacccat ggaagacggc
     5761 atgttgcatt tccatgagtg gtacctgagc aacatgggag agcagcttgg tgacagcgcc
     5821 gcgccgcatg tcgcatcgac ccaacggccc atgccatttc gctcatgaaa taaaagcgaa
     5881 tgaattgcat tatcattaac agctcatgcg gaccaggcct cctccggcaa cgccaatgac
     5941 acaaccgacg ctccccccac cgccccgcac ccgattcacg gtctcggact tcaaccgcat
     6001 gggcgggtcg gtcggcttca attaccgctt gcccggccag gaaggcgggg gcgccggcat
     6061 tgagaacctt tgcatcgccg agggccgtgt ggaggaatgt gagatccgcc ccggcatcac
     6121 cctgatcgtc tccgacgtgc atgtgtatca tcattacgaa tcgacgtccg tcatgacgcc
     6181 gcgcttttca gccatcgtta tgctccaggg ccaggcccgg gctcggctgg acaagcagga
     6241 cgacgtgcgc ctggccgctc agagcggcct caatgcgcta tatggcgata ccgtcgccat
     6301 gacgggcgtt catccggccg gccagcgtct gcgcagcgtc aatctctccg tgacggcccc
     6361 tgaagcggcc gacgatgagt acaccagcga aatcatatgg aaactcatgc agtcctcggc
     6421 gcccaggctg cgccgctggc cggtgccgca ccatttgctg ctatccattg agcatctgct
     6481 ggaatgcgac tgggatcaac ctctacgcaa tatggtgcgt gaaggcgtgg gcacgcaact
     6541 gctggcccac gccttggctg cgctgcaaca cgcccctgtg acccaccgcg gcctgaccca
     6601 gcgggatcgc cagcttctgg agagggtgcg cgagcgcctg cacgaggcgc ccggcgaaga
     6661 ccatactctg gatgacctgg cgcgactggc ctgcatgagt ccaagcacgc tgcgtgcaaa
     6721 gttccatgcc gtgtatcacc gttcggtatt cagctggctg cgcgaacgcc gcctggaggt
     6781 tgcccgcgaa caattggctc ggggttggag cgtacagcag gcggcgcact tcgtcggcta
     6841 ccgccacgcg accaatttcg ccacggcgtt tcgcgaacgc tacggcgtcg cgcccagtca
     6901 actcggttag cggctggtgc cttgcggcgg caggcattga cattgcggca ttgaccatcc
     6961 cattcctgtt accagctgga tcatcatgga aggccgctgc ccgctccggg cggccttgtc
     7021 catggagccg ccatgagccg cgccgcgtcg gccccctcat attcgctcat gatggtaatg
     7081 ctggggctgc tgtcctgcgt cgcacccgcc agcatcgacg cctacctgcc agccttcggc
     7141 gcgctgcaac gcgagttcgg cgtaccccag gaaaccgtgc aactcacgct cggcgtatac
     7201 atgttctgct atgcggcgat gctcttgctg cacggaacac tgtctgactc tctgggcagg
     7261 cgtcgcgttg tgctgggcgc cctgggcttc tatgtttggg gcgccctgct tgccacggcc
     7321 gcacccggtt ttggctggct gctggcggcc cgggccctgc agggactgtc cgccggcgcc
     7381 ggggtcgtgg taggacaggc catcatccgc gattgctatc agggcgcagc ggcacaacgc
     7441 agcatgtctt atctgatcct ggtgttcaat ctatcgcccg cgctcgcgcc cgtcatcgga
     7501 ggtcaattgg ccgtccatca tggttggcgt tcgatcttct tcatgttggg gcttctggcc
     7561 gccactgccc tgaccctatg cgcctggcgc ctaccagaaa cgctcgcgcc cgccaagcgc
     7621 caaacgctct ccttgcgggg tctggccgcg ggctatcgtg aggtgttgcg caatggaaat
     7681 ttcaccgcgc ccggcctggc gttcagcctg gtcttcgccg cacagggcct gctgatcggt
     7741 gcggcgccgg atttcatcgc caatgtgctc gatctgcccg aaaccaactt tgcctatcta
     7801 ttcgtccctc tggtggccgg cgcgatgacc ggggccgcga tcgcggcgcg gcatgccgga
     7861 cgttggcgcg atacacggat catcggactg gcctatctgc tcatgaacgg tagttgcctc
     7921 gcctacgcca tctatttttg gaccgccttg tcgccggcac tgccctgggc ggtgctgccc
     7981 cccgctttat tcacctgcgg attggccatg tcggtgcctg ccatgacgtt gcacatcctg
     8041 gagtctgtgc ccgcgctctc cggcacaggg gcctcggtgc tgggtttcat gcagatgctg
     8101 gccttttcga tagccagcgg ctggggcgta ccgctgacct atgggcagcc ctcggtcctg
     8161 gccctggcca tgctggcctg cgtgacggca agcgcgctgg cctgggcgtg gttgcagcat
     8221 ttatcgagaa tatcggccaa ggtccaggca cgctgaacat cttcggcgtt ttccatacgc
     8281 actccgtcat cgccgataca accgtccgat tacaaaaaag ataattccta ttccctttaa
     8341 tttcttgccg tcttgcatct gtccccatgc cagatcccgc tcacttctcc ccggcgcatt
     8401 cgcgccgttt gcgtttcttt gcccacgttc tgcacctgct cggcgcactc tttacccagc
     8461 acgccctggc ccaggaagcg cgaacgggga acgatatcgc tcagttgccc gccataagcg
     8521 tcacgggtcg tgagatttcc gacctcaccg agggtacaaa cgcctacaca accgaggcca
     8581 tgagcacggc cacgggcctg acactctcgc cacgcgaaac accacaatcc gtcagtgtgg
     8641 tcacccgaca gcagatcgag gatcagggcc tcaccgacac cggcgccatc ctggcgaccg
     8701 cgccagggat ttccgtcacg cgcagcgaca gcaaccgcta ttcattctcg gcccgcggct
     8761 tcaccatcga caacttccag tttgacggcc tggtatcgcc catcctgagc caatggaact
     8821 atggttcgac cgatatggac gccgccatct acgatcacgt ggaaatcgta cgtggcgcca
     8881 caggcctgat gacaggctcg ggcaatcctt cagccgccgt gaacttcgtg cgcaagcgtc
     8941 ccttgcgtga gttcgcggct acgttcaatg cgagtgtcgg cagctgggac tatgtgcgcg
     9001 gcgatgccga catctccgtg cccatcacgg aagacggcag aatacggtca cgcttggtgg
     9061 ccgcctacag tcagggcgac agctatgtgc actttttaga tacgcgccgg cgcacattct
     9121 atggcgtggt cagcgccgat ctgacgccgg atacggtgct gacgaccagc gtggagtacc
     9181 agcacaacca cagcaatggg tttggcagcg gctttccgct gttctatagc gacggttcgc
     9241 gcaccgattt caaccgctcg gtggccaaca acgctccctg ggcccggcag gataccgaag
     9301 ccaccaccta tttcgtggac ctcacgcacc gcttcaccaa tgactggaag ctgcgcgcgg
     9361 cctatagcca cactgatggc cgctatctca tgaaacatgt gtaccggggc ggctaccccg
     9421 atcgccatac tggcatcatc gctgcccccc ctgcattttc caactacgac ggcaacctcg
     9481 atcgggatga catccatttt tccttgtccg ctcctttcga ggccttcggc ctgcgccacg
     9541 aagttgccct gggctggatg agcatcgaca accatagcga catccagcga tacgcaatgg
     9601 tcggaccggc cccagccatc ggcagcttct tcgactggcg ccgcgcccac atccaagagc
     9661 ccagctgggc cgacacgctg tcgcccgccg acgacgtgcg caccaagcag accggcgcct
     9721 atctggtcgg ccggtttgca ctagccgaac ccctgcacct catcgtgggc gaccgttgga
     9781 gcgactggaa aaccaaacag atgtattttg gctcgcgccg cgaatacagg atcaagaatc
     9841 agttcacccc ctatgccggt ctgacctacg acatcaacga cacctacacg gcgtacgcca
     9901 gctatacgga gatcttccag ccgcagaacg cgcgcgacac cagcggcggc attcttcctc
     9961 ccatcaaaag caagagctat gagctgggtc tgaaggcagc ctatctggag ggacggctca
    10021 atacctccgc cgcgctcttt cagacgcggc aggataacct ggcccaggtc atcccgggct
    10081 catccattcc gggctttccg aacatgcagg cctcacgtgc cgcctccggc gccaaggtcg
    10141 aggggataga cctggaggcc agcggccaga tcctgcccga ctggaacatc ggcgccagct
    10201 atacacactt caccaccaag gacgccagcg gcaaccccat caacaccaat catccgcgca
    10261 gcctgttcaa gctctacacc acgtaccgcc tgccgggcgc cctgcaccgg cttaccgtgg
    10321 gcggcggcgt tgactggcaa agtcgcatgt accaggccgc agccagtccg cgcggcaatg
    10381 tcgaagtcga acaggacagc tacgcactcg tgagcctcat ggcgcgcttc gactttaaca
    10441 aaaaactgtc ggcaacactg aacgtgaaca atctgttcga caaaaagtac tacgatcaga
    10501 tcggcttcta cagccagggt tggtggggtg cgccacgcaa tgtaatgctc aacttgcggg
    10561 cgcagtattg a
//
