BGC0002465: amphibactin E biosynthetic gene cluster from Alcanivorax borkumensis SK2
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Location: 2,377,165 - 2,399,998 nt. (total: 22,834 nt).
This entry is originally from NCBI GenBank AM286690.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002465
Short description amphibactin E biosynthetic gene cluster from Alcanivorax borkumensis SK2
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AM286690.1
2377165 - 2399998
via
Compounds
  • amphibactin E
  • amphibactin H
  • amphibactin I
Species Alcanivorax borkumensis SK2 [taxonomy]
References
Chemical products information
amphibactin E Evidence:
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amphibactin H Evidence:
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amphibactin I Evidence:
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABO_2087
  • CAL17535.1
 2377165 - 2377857 (+) siderophore biosynthesis protein, putative
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    • ABO_2088
    • CAL17536.1
    		 2377980 - 2378711 (-) ferric iron reductase protein, putative
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      • ABO_2089
      • CAL17537.1
      		 2378711 - 2380003 (-) L-ornithine N5-oxygenase
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        • ABO_2090
        • CAL17538.1
        • iucB
        		 2380154 - 2381140 (-) siderophore biosynthesis protein
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          • ABO_2091
          • CAL17539.1
          • foxA
          		 2381130 - 2383367 (-) Ferrioxamine receptor precursor
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            • ABO_2092
            • CAL17540.1
            		 2383468 - 2388942 (-) peptide synthetase, putative
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              • ABO_2093
              • CAL17541.1
              		 2388956 - 2399758 (-) peptide synthetase, putative
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                • ABO_2094
                • CAL17542.1
                		 2399795 - 2399998 (-) MbtH-family protein
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                  Biosynthesis information

                  Biosynthetic modules

                  Name
                  1
                  Type
                  nrps-type1
                  Genes
                  ABO_2093
                  Substrates
                  N5-acetyl-N5-hydroxyornithine (evidence: Structure-based inference [1], Sequence-based prediction [1])
                  Integrated Monomers
                  Domains
                  condensation (LCL), adenylation, epimerase, carrier (PCP)
                  Name
                  2
                  Type
                  nrps-type1
                  Genes
                  ABO_2093
                  Substrates
                  N5-acetyl-N5-hydroxyornithine (evidence: Structure-based inference [1])
                  Integrated Monomers
                  Domains
                  condensation (DCL), adenylation, carrier (PCP)
                  Name
                  3
                  Type
                  nrps-type1
                  Genes
                  ABO_2093
                  Substrates
                  Serine (evidence: Structure-based inference [1])
                  Integrated Monomers
                  Domains
                  condensation (LCL), adenylation, carrier (PCP)
                  Name
                  4
                  Type
                  nrps-type1
                  Genes
                  ABO_2092
                  Substrates
                  N5-acetyl-N5-hydroxyornithine (evidence: Structure-based inference [1])
                  Integrated Monomers
                  Domains
                  condensation (LCL), adenylation, epimerase, carrier (PCP)
                  Annotation changelog

                  Entry version: next

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2024-03-19
                  MIBiG v4 annotathon
                  • (ID: H5KVDLSVQ3TJW7SKCDNBDEVC)
                  • (ID: N36AXMAR75OH4EWIMJIU5WOH)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Entry added
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
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