LOCUS       BGC0002468             24259 bp    DNA     linear   BCT 03-APR-2020
DEFINITION  Vibrio anguillarum 775 plasmid pJM1, complete sequence.
ACCESSION   BGC0002468
VERSION     BGC0002468
KEYWORDS    .
SOURCE      Vibrio anguillarum 775
  ORGANISM  Vibrio anguillarum 775
            Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
COMMENT     On or before Nov 9, 2003 this sequence version replaced M74068.1,
            J03529.1, Z33880.1, L40497.1, L40498.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:46:49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24259
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..2118)
                     /NRPS_PKS="Domain: PCP (185-252). E-value: 8e-18. Score:
                     56.3. Matches aSDomain: nrpspksdomains_angM_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (276-569). E-value:
                     6.8e-60. Score: 194.4. Matches aSDomain:
                     nrpspksdomains_angM_Condensation_LCL.1"
                     /codon_start=1
                     /gene="angM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     195; E-value: 4.4e-59)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF1; involved in anguibactin biosynthesis"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="AAA81775.2"
                     /sec_met_domain="PP-binding (E-value: 2.1e-13, bitscore:
                     40.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.5e-45, bitscore:
                     143.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVKSKPKTLLSISEHEEEVWIQQLQDPRSIEWTVDAYTIDINS
                     KNEQLIQAVKKLVLNDIQLNLRYRFSDEFELEKWHSVDSEGLTNVAQVEGEKLSDRVAD
                     IKLRLWEPDFQPPFGVDILQEGKEKYLLISTHPILDLHLKNKSIINNIESNYEFLNTLN
                     FESKLNPIYLDISKIDNNNNNIEQIILSEFRASLDDPEVELGDDFFEMGGHSLLATRII
                     GNLMNNHDIEISFNDFFKSPSAQALARCVSLTDKSSRNKPVDMALPHGSTSIGSKLPLS
                     FAQSFLWNAHLATGQCAIFNLPFAMRFDAEVDEEVFKLAFSDLLIRHTGLRTLFNEGTD
                     GSIQQVIDEKDLIQYSWFWSSAESGTSSLESEASYVFDLSKELPLRIRFFKDRKTNQQV
                     LSFLIHHMIIDEWSLNNLMSELSDAYLARSQNQEPEWDKSAYSIHDYALAQKNRGPIAE
                     DINYWVNHLRGSTSGLNLTCTEPDQNGPEVNPIEANWIEIDLGPSAYHSVHSLAREYNS
                     SIFSVVYSAIAQALHNAGNLKDLVIGTSASGRDDAKYFDSVGYFTTMVAHRVIFEPDQS
                     FGKLIENVTMTINDSMPHATVPIDMVQRELGLDPKNGLLFDVYAQIHADNALYGSLQTP
                     NNIPVPYQQILPNKNKSLFGLHFEIMENVIGDERTLRLIVTYQTARYNAKQVVSIGQQM
                     KVTLTGQTVHQ"
     gene            complement(1..2163)
                     /gene="angM"
     subregion       1..24259
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24259
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        complement(412..1290)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angM_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.80E-60"
                     /label="angM_Condensation_LCL.1"
                     /locus_tag="angM"
                     /protein_end="569"
                     /protein_start="276"
                     /score="194.4"
                     /tool="antismash"
                     /translation="KLPLSFAQSFLWNAHLATGQCAIFNLPFAMRFDAEVDEEVFKLAF
                     SDLLIRHTGLRTLFNEGTDGSIQQVIDEKDLIQYSWFWSSAESGTSSLESEASYVFDLS
                     KELPLRIRFFKDRKTNQQVLSFLIHHMIIDEWSLNNLMSELSDAYLARSQNQEPEWDKS
                     AYSIHDYALAQKNRGPIAEDINYWVNHLRGSTSGLNLTCTEPDQNGPEVNPIEANWIEI
                     DLGPSAYHSVHSLAREYNSSIFSVVYSAIAQALHNAGNLKDLVIGTSASGRDDAKYFDS
                     VGYFTTMVAHRV"
     CDS_motif       complement(421..504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angM_0003"
                     /evalue="3.20E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="angM"
                     /protein_end="566"
                     /protein_start="538"
                     /score="19.6"
                     /tool="antismash"
                     /translation="DLVIGTSASGRDDAKYFDSVGYFTTMVA"
     CDS_motif       complement(844..909)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angM_0002"
                     /evalue="5.80E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="angM"
                     /protein_end="425"
                     /protein_start="403"
                     /score="25.3"
                     /tool="antismash"
                     /translation="IHHMIIDEWSLNNLMSELSDAY"
     CDS_motif       complement(1114..1224)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angM_0001"
                     /evalue="4.00E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="angM"
                     /protein_end="335"
                     /protein_start="298"
                     /score="25.7"
                     /tool="antismash"
                     /translation="IFNLPFAMRFDAEVDEEVFKLAFSDLLIRHTGLRTLF"
     aSDomain        complement(1363..1563)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angM_PCP.1"
                     /evalue="8.00E-18"
                     /label="angM_PCP.1"
                     /locus_tag="angM"
                     /protein_end="252"
                     /protein_start="185"
                     /score="56.3"
                     /tool="antismash"
                     /translation="EQIILSEFRASLDDPEVELGDDFFEMGGHSLLATRIIGNLMNNHD
                     IEISFNDFFKSPSAQALARCVS"
     regulatory      complement(2135..2140)
                     /gene="angM"
                     /regulatory_class="minus_10_signal"
     mobile_element  2153..3193
                     /mobile_element_type="insertion sequence:ISVA1"
     regulatory      complement(2158..2163)
                     /gene="angM"
                     /regulatory_class="minus_35_signal"
     CDS             complement(2207..3115)
                     /codon_start=1
                     /note="ORF2"
                     /product="putative transposase"
                     /protein_id="AAA81774.2"
                     /transl_table=11
                     /translation="MGKAKKKITNWAEYNKALCKRGSVTFWIDDSAIDAWRCRTHHGKR
                     GRGFQYSDTAIETALMIKGIFSLPLRALQGFIDSIFELLDAPLTSPDYTCISKRSKTVQ
                     VKYRNKSKGAIRHIAIDSTGLKVFGEGEWKVKKHGAEKRRTWRKLHLAVDIETHETISA
                     EVSLVSVGDNEVLPTLLNPLRRKIHTVSADGAYDTKSCHETLKNKGCTPLIPPRNNAAL
                     WEDGHPRNEAVEALKNGTITEWKSESGYHYRSISETAMSRYKGLTSGKLSLRCYNAQVG
                     EIMANVKAINKVIGLGMPVRS"
     regulatory      3565..3570
                     /gene="fatD"
                     /regulatory_class="ribosome_binding_site"
     gene            3565..4522
                     /gene="fatD"
     CDS             3578..4522
                     /codon_start=1
                     /gene="fatD"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 204.7; E-value: 3e-62)"
                     /gene_kind="transport"
                     /note="ORF3"
                     /product="ferric anguibactin transport protein"
                     /protein_id="AAR12524.1"
                     /transl_table=11
                     /translation="MTFRMILAFFTLCATSLFFGANQIEWSLLPTFNEKAWLPIIASRL
                     PRLVALILTGSGLAMCGVILQHIVRNRFVEPGTTGSLDAAKLGILVSIVMLPSSDKLER
                     MFFAVLFCFAAGLVYIAIIRKVKFSNTALVPVIGLMFGSVLSALAEFYAYQNNILQSMS
                     GWLMGDFSKVVQEHYEIIFLILPITLLTYLYAHRFTVMGMGEDIASNLGISYAMTAALG
                     LILVSITVAVTVVTVGAIHFVGLVIPNLVALKYGDHLKNTLPIVALGGASLLIFCDVIS
                     RVVLFPFEVPVGLTASAVGGVMFLAFLLKGAKA"
     regulatory      4515..4520
                     /gene="fatC"
                     /regulatory_class="ribosome_binding_site"
     gene            4515..5472
                     /gene="fatC"
     CDS             4519..5472
                     /codon_start=1
                     /gene="fatC"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 77.7; E-value: 1.3e-23)"
                     /gene_kind="transport"
                     /note="ORF4"
                     /product="ferric anguibactin transport protein"
                     /protein_id="AAR12525.1"
                     /transl_table=11
                     /translation="MTSLNLNFRVSVVLVILLSIAFIFINSGFDLEYIIPRRLIKLSAI
                     IIGGSCVAISAVIFQALARNRILTPSIMGYESIYLVWQALLLLFVGTSGSAVLGVVGNF
                     VVSAVLILLYSFVIQFWVLKRFQHDMHQVLLIGFVLTMVLTTVAQFIQIRISPGEFSIF
                     QGLSYTSFERAKPSTLLFAGTVLSILALFANKWVSELDVIGLGRDQAMSLGLNDAHYIP
                     KYFSVIAILVAISTSLIGPTAFMGVFIANIAYSITGSPQYRHTLPVACTIAIVMFLTAQ
                     LMVEHFFNYKTTVSILVNVLCGGYFLIITMRARSQL"
     gene            5526..6494
                     /gene="fatB"
     CDS             5526..6494
                     /codon_start=1
                     /gene="fatB"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 244.9; E-value:
                     1.5e-74)"
                     /gene_kind="transport"
                     /note="ORF5; 40 kDa protein"
                     /product="ferric anguibactin transport protein"
                     /protein_id="AAR12526.1"
                     /transl_table=11
                     /translation="MFKSTLNIAVAIVCSSLVTLTGCEPKVAQSQVIQPLETPIVIEHN
                     LGQTVISNRPQRVAALDMNEVDFLDQLNVPIAGMVKDFVPHFLEKYKNTPDISDLGAIV
                     QPNMEKIYALKPDLVLMTPLHANQYEELSKLAPTVHFDIDFRNSHGHHVDIIKQHVIDL
                     GEIFNKQTLAQKKVAEIDAKVDEVQALTAERSEKALVVMHNNGSFSSFGIESRYGFVFD
                     VLGVKPASTEIAASLHGQPISSEFINQANPDILYIIDRTAVMEGKPVIDAEHLANPLLR
                     QTKAWKNGKVIFVDADAWYITSASITSLKIVIDDIIKGYQS"
     misc_RNA        complement(5576..6254)
                     /product="antisense RNA alpha"
     CDS             6598..8778
                     /codon_start=1
                     /gene="fatA"
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     532.4; E-value: 3e-161)"
                     /gene_kind="transport"
                     /note="ORF6; outer membrane receptor"
                     /product="ferric anguibactin receptor"
                     /protein_id="AAR12527.1"
                     /transl_table=11
                     /translation="MTHQVATCHKKQSFSGKPTLSRIALLVALQISASALPISITHAEE
                     QADESITVYGQANEAYAAGKISKASSIGMLGDKDFLDTPFNAIGYTDKHIQDQHAQDIS
                     DVISASDPSVFTSGETGLNKESFKIRGFSSDIGDVMFNGLYGIAPYYRSSPEMYQRIDV
                     LKGPASLLNGMPPNGSVGGSINLVTKRAQEAPITSFTGTYMSDSQFGGHIDIGRRFGEN
                     EQFGVRFNGVFRDGDASVDGQSRKAQLASLSLDWRNDIALIEADLYFSTERVDGPNRGL
                     SIASGVDVPSPPSSDTLLSPSWAYNDSEDKGMMIRAELDLSNSVTAYGAVGASRTDFDS
                     NVPQRVKIIDDSGTLEVSLGSVKLESKRTSGEVGIRSSFDTGPIEHYLVLNSTYFREDK
                     NDSPTGNNNPGSWNPNIYNPVWGPEDSTYDNYYELPVDSTQISFGVADTLSLANGKYQV
                     TLGLRHQSIDYESGVTWNGNAFPTTKLKESTYTPAIVALYKVSDSVSLYGNYTEGLTNG
                     KTAGSGAANVGEAFEPQKTKQTEAGLKLDMNDFAHTFSLFEIKKPNGYQDPDTNIYSFG
                     GEQRNRGIEWGFYGTVLEDYTLTGGIAYTDAEITKATDVTTEGKQATKLPDLQAKLALE
                     WNLPVMRQLTLIGQANYMSEQYIDAQNTQSLSAQTIFDLGARYNSTIANQSVIWRLAVN
                     NVTDEAYWTTTHYASLALGAPRTVMLSATADF"
     gene            6598..8818
                     /gene="fatA"
     misc_RNA        complement(8558..8984)
                     /product="antisense RNA beta"
     regulatory      8792..8818
                     /gene="fatA"
                     /note="rho-dependent terminator; putative"
                     /regulatory_class="terminator"
     gene            8863..12009
                     /gene="angR"
     CDS             8863..12009
                     /NRPS_PKS="Domain: Heterocyclization (14-296). E-value:
                     5.4e-39. Score: 126.2. Matches aSDomain:
                     nrpspksdomains_angR_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (458-855). E-value: 4.1e-93.
                     Score: 304.0. Matches aSDomain:
                     nrpspksdomains_angR_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 4.5e-11. Score:
                     34.7. Matches aSDomain: nrpspksdomains_angR_PCP.1"
                     /codon_start=1
                     /gene="angR"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     324.5; E-value: 1.6e-98)"
                     /gene_kind="biosynthetic"
                     /note="ORF7; involved in anguibactin biosynthesis and
                     regulation"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="AAR12528.1"
                     /sec_met_domain="Condensation (E-value: 1.4e-17, bitscore:
                     53.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-102, bitscore:
                     333.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-07, bitscore:
                     21.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQNEHPFAFPETKLPLTSNQNWQLSTQRQRTEKKSITNFTYQEF
                     DYENISRDTLERCLTTIIKHHPIFGAKLSDDFYLHFPSKTHIETFAVNDLSNALKQDID
                     KQLADTRSAVTKSRSQAIISIMFSILPKNIIRLHVRFNSVVVDNPSVTLFFEQLTQLLS
                     GSPLSFLNQEQTISAYNHKVNNELLSVDLESARWNEYILTLPSSANLPTICEPEKLDET
                     DITRRCITLSQRKWQQLVTVSKKHNVTPEITLASIFSTVLSLWGHQKYLMMRFDITKIN
                     DYTGIIGQFTEPLLVGMSGFEQSFLSLVKNNQKKFEEAYHYDVKVPVFQCVNKLSNISD
                     SHRYPANITFSSELLNTNHSKKAVWGCRQSANTWLSLHAVIEQEQLVLQWDSQDAIFPK
                     DMIKDMLHSYTDLLDLLSQKDVNWAQPLPTLLPKHQESIRNKINQQGDLELTKELLHQR
                     FFKNVESTPNALAIIHGQESLDYITLASYAKSCAGALTEAGVKSGDRVAVTMNKGIGQI
                     VAVLGILYAGAIYVPVSLDQPQERRESIYQGAGINVILINESDSKNSPSNDLFFFLDWQ
                     TAIKSEPMRSPQDVAPSQPAYIIYTSGSTGTPKGVVISHQGALNTCIAINRRYQIGKND
                     RVLALSALHFDLSVYDIFGLLSAGGTIVLVSELERRDPIAWCQAIEEHNVTMWNSVPAL
                     FDMLLTYATCFNSIAPSKLRLTMLSGDWIGLDLPQRYRNYRVDGQFIAMGGATEASIWS
                     NVFDVEKVPMEWRSIPYGYPLPRQQYRVVDDLGRDCPDWVAGELWIGGDGIALGYFDDE
                     LKTQAQFLHIDGHAWYRTGDMGCYWPDGTLEFLGRRDKQVKVGGYRIELGEIEVALNNI
                     PGVQRAVAIAVGNKDKTLAAFIVMDSEQAPIVTAPLDAEEVQLLLNKQLPNYMVPKRII
                     FLETFPLTANGKVDHKALTRMTNREKKTSQSINKPIITASEDRVAKIWNDVLGPTELYK
                     SSDFFLSGGDAYNAIEVVKRCHKAGYLIKLSMLYRYSTIEAFAIIMDRCRLAPQEEAEL
                     "
     aSDomain        8905..9750
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angR_Heterocyclization.1"
                     /evalue="5.40E-39"
                     /label="angR_Heterocyclization.1"
                     /locus_tag="angR"
                     /protein_end="296"
                     /protein_start="14"
                     /score="126.2"
                     /tool="antismash"
                     /translation="LPLTSNQNWQLSTQRQRTEKKSITNFTYQEFDYENISRDTLERCL
                     TTIIKHHPIFGAKLSDDFYLHFPSKTHIETFAVNDLSNALKQDIDKQLADTRSAVTKSR
                     SQAIISIMFSILPKNIIRLHVRFNSVVVDNPSVTLFFEQLTQLLSGSPLSFLNQEQTIS
                     AYNHKVNNELLSVDLESARWNEYILTLPSSANLPTICEPEKLDETDITRRCITLSQRKW
                     QQLVTVSKKHNVTPEITLASIFSTVLSLWGHQKYLMMRFDITKINDYTGIIGQFTEPLL
                     V"
     aSModule        8905..11970
                     /complete
                     /domains="nrpspksdomains_angR_Heterocyclization.1"
                     /domains="nrpspksdomains_angR_AMP-binding.1"
                     /domains="nrpspksdomains_angR_PCP.1"
                     /locus_tags="angR"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        10237..11427
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angR_AMP-binding.1"
                     /evalue="4.10E-93"
                     /label="angR_AMP-binding.1"
                     /locus_tag="angR"
                     /protein_end="855"
                     /protein_start="458"
                     /score="304.0"
                     /tool="antismash"
                     /translation="FFKNVESTPNALAIIHGQESLDYITLASYAKSCAGALTEAGVKSG
                     DRVAVTMNKGIGQIVAVLGILYAGAIYVPVSLDQPQERRESIYQGAGINVILINESDSK
                     NSPSNDLFFFLDWQTAIKSEPMRSPQDVAPSQPAYIIYTSGSTGTPKGVVISHQGALNT
                     CIAINRRYQIGKNDRVLALSALHFDLSVYDIFGLLSAGGTIVLVSELERRDPIAWCQAI
                     EEHNVTMWNSVPALFDMLLTYATCFNSIAPSKLRLTMLSGDWIGLDLPQRYRNYRVDGQ
                     FIAMGGATEASIWSNVFDVEKVPMEWRSIPYGYPLPRQQYRVVDDLGRDCPDWVAGELW
                     IGGDGIALGYFDDELKTQAQFLHIDGHAWYRTGDMGCYWPDGTLEFLGRRDKQVKVG"
     CDS_motif       10423..10461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angR_0001"
                     /evalue="8.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="angR"
                     /protein_end="533"
                     /protein_start="520"
                     /score="12.8"
                     /tool="antismash"
                     /translation="LGILYAGAIYVPV"
     CDS_motif       10648..10707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angR_0002"
                     /evalue="5.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="angR"
                     /protein_end="615"
                     /protein_start="595"
                     /score="34.2"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGVVISH"
     CDS_motif       10822..10857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angR_0003"
                     /evalue="5.30E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="angR"
                     /protein_end="665"
                     /protein_start="653"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="GLLSAGGTIVLV"
     CDS_motif       11230..11319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angR_0004"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="angR"
                     /protein_end="819"
                     /protein_start="789"
                     /score="34.3"
                     /tool="antismash"
                     /translation="PDWVAGELWIGGDGIALGYFDDELKTQAQF"
     CDS_motif       11392..11457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angR_0005"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="angR"
                     /protein_end="865"
                     /protein_start="843"
                     /score="33.4"
                     /tool="antismash"
                     /translation="FLGRRDKQVKVGGYRIELGEIE"
     aSDomain        11773..11970
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angR_PCP.1"
                     /evalue="4.50E-11"
                     /label="angR_PCP.1"
                     /locus_tag="angR"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="34.7"
                     /tool="antismash"
                     /translation="EDRVAKIWNDVLGPTELYKSSDFFLSGGDAYNAIEVVKRCHKAGY
                     LIKLSMLYRYSTIEAFAIIMD"
     gene            12006..12764
                     /gene="angT"
     CDS             12006..12764
                     /NRPS_PKS="Domain: Thioesterase (17-244). E-value: 1.5e-49.
                     Score: 161.3. Matches aSDomain:
                     nrpspksdomains_angT_Thioesterase.1"
                     /codon_start=1
                     /gene="angT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 217.1; E-value: 3.2e-66)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF8; involved in anguibactin biosynthesis"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="AAR12529.1"
                     /transl_table=11
                     /translation="MSPLIKLAASSRLHDATHYVLCPFAGGGSGAFRHWRTLSLENEVI
                     SVMLYPGREFRIDDPTVINIGTLAEEMIQALKTCNQRIEDTIIVGHSMGAQVAYEASKK
                     LVNQGLFLKGLIISGCQAPHIKGRRLLGECDDKTFIHNLVEIGGCDPSLAKSPEWWPIF
                     LPALRADFTATEQYIFTSLPNDKEGLPIPTLLISGDQDREANFSEIEEWKLWCNKVVDH
                     LVVEGGHFYITEQPQMMLECIRALSTETTA"
     aSDomain        12057..12737
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angT_Thioesterase.1"
                     /evalue="1.50E-49"
                     /label="angT_Thioesterase.1"
                     /locus_tag="angT"
                     /protein_end="244"
                     /protein_start="17"
                     /score="161.3"
                     /tool="antismash"
                     /translation="HYVLCPFAGGGSGAFRHWRTLSLENEVISVMLYPGREFRIDDPTV
                     INIGTLAEEMIQALKTCNQRIEDTIIVGHSMGAQVAYEASKKLVNQGLFLKGLIISGCQ
                     APHIKGRRLLGECDDKTFIHNLVEIGGCDPSLAKSPEWWPIFLPALRADFTATEQYIFT
                     SLPNDKEGLPIPTLLISGDQDREANFSEIEEWKLWCNKVVDHLVVEGGHFYITEQPQMM
                     LECIR"
     CDS_motif       12267..12320
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angT_0001"
                     /evalue="3.20E-05"
                     /label="NRPS-te1"
                     /locus_tag="angT"
                     /protein_end="105"
                     /protein_start="87"
                     /score="16.5"
                     /tool="antismash"
                     /translation="IVGHSMGAQVAYEASKKL"
     gene            complement(12862..14190)
                     /gene="angU"
     CDS             complement(12862..14190)
                     /codon_start=1
                     /gene="angU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 459.3;
                     E-value: 1.8e-139)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF9; involved in anguibactin biosynthesis"
                     /product="putative monooxygenase"
                     /protein_id="AAR12530.1"
                     /transl_table=11
                     /translation="MVNTIIKDIIGVGIGPFNLGLAALTSHHPELDVEFIERRQEFNWH
                     SGMLLPGATLQVPFLADLVTMADPTHPLSYLNYLKQHDRLYQFYYYETFLVPRSEYNHY
                     CQWAAGKLENCAYGETVVDVKYLKDIECFTIQSQLNEGEVKTRYSRDLSIGVGTIPWLP
                     QWAKSTNHSLVQHSARFGHMREQLAKCNSVTVVGSGQSAAECVLNLYRDLSLEQIEAGA
                     RVNWVTRSAGFHPMEASKLGQECFTPAYMHYFHTLSREKRRSIVEGQGQLYKGISGYTI
                     AEIFDLLYERSIGGRSPGLSLYSNSQVNEVVISVNNQEMEVQCYQSQQEQTFHLRTNAV
                     ICATGYAHQWPKWLNDLKGSVLATDEHGDLIVEKDFIAQRCDQGVGRVFVQNPEIFQHG
                     VGGPDLGMGAYRNASIINQVLGKQIYRLPESSAFQSYGIPETK"
     gene            complement(14314..17184)
                     /gene="angN"
     CDS             complement(14314..17184)
                     /NRPS_PKS="Domain: Heterocyclization (2-295). E-value:
                     1.5e-72. Score: 236.4. Matches aSDomain:
                     nrpspksdomains_angN_Heterocyclization.1"
                     /NRPS_PKS="Domain: Heterocyclization (446-704). E-value:
                     7.7e-33. Score: 106.0. Matches aSDomain:
                     nrpspksdomains_angN_Heterocyclization.2"
                     /codon_start=1
                     /gene="angN"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Cy_tandem"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     72.7; E-value: 5.6e-22)"
                     /gene_kind="biosynthetic"
                     /note="ORF10; involved in anguibactin biosynthesis"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="AAR12531.1"
                     /sec_met_domain="Condensation (E-value: 4.5e-37, bitscore:
                     117.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Cy_tandem (E-value: 6.3e-177, bitscore:
                     578.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELTPMQAACWFGRKDNGQLGNVASHLYTEFDGENINIDKLNSA
                     LGSLYKRHEMLRLKVNHLGESSIIDVPNHALLEIEDFTHLSPENMHKALIEKRQSWAHQ
                     MLDLTQGQVARFSVSLLPDNAFRLHIDSDMIAIDPDSCRVLIEDLAMLYESGASEVKNN
                     PTFFSWHGMAKNDPILKSQRKSDRAWWKSNLNNIAPSPSLPFFEPNTNKAESHHYSAWL
                     DAEQRTDLITLARKNNLTPANLMLGLFARTLGKATGDETFRINVPTFWRPPIIEGTESL
                     VGDFVNFVVLSVDMKESKTLLEFCHMVADKMGLLLGHSRYDGVSMMRDLSLHHGCTQLA
                     PVVFTSAIDLPSGNLFSRRVHKHFGKMDWTISQGSHVALDSQVVSIDGGIMINWDVRQE
                     ALPKEWTSAMFENFVALTKSVISTPDLLVAPLDKLQPKLVCLSHFESELTPMQRAYLLG
                     RTTQMPLGGVAMQETLEHRGTLSASSIRHRLSTMVVKYPCLRTFIDSKSLKLQVSQCPQ
                     VNLAHVDLRHLEKDKAEEELARFRYTYNHNMFDLDQPLWNVTTFSLSETDTYVFSRFDA
                     LILDARSIASLLVELFDEQAPYIPSFDFEPDHEHVQSARAKDEKYWLNKLATVEKSMCF
                     PWHKPLKSISHSRYQRQSLKIEKETVKKLVRVAGKEGLYKNTLMMSVAMEALSSHVCNG
                     QLCVAVPVLPMTSANYASQSSFIVTQWNAHQYDFLQRAKTLQVDTLEGLEHLAFSGVDL
                     ARVLFERCGPAPALPIVITNGLSWPVLSDDASMTLQRGLTQTPQVAMDIRFVAITGGSI
                     MFSVDYASEAVADDLVKAILDRIDMILDHMVETSQYVVQSHKLLPIGRSRVVELVDRDP
                     NESWDIDLTKRKIFDIYCQVIGKEKNNSDSDSLPFSQLGLRPSHLKQISIDLNKELQVD
                     LPVMQLIRCRNADDVKDLALQQVVDF"
     CDS_motif       complement(14857..14886)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0013"
                     /evalue="2.80E+00"
                     /label="Cy6"
                     /locus_tag="angN"
                     /protein_end="776"
                     /protein_start="766"
                     /score="1.9"
                     /tool="antismash"
                     /translation="LPIVITNGLS"
     CDS_motif       complement(14920..14958)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0012"
                     /evalue="7.00E-03"
                     /label="afterCy5"
                     /locus_tag="angN"
                     /protein_end="755"
                     /protein_start="742"
                     /score="9.5"
                     /tool="antismash"
                     /translation="LEHLAFSGVDLAR"
     aSDomain        complement(15073..15846)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angN_Heterocyclization.2"
                     /evalue="7.70E-33"
                     /label="angN_Heterocyclization.2"
                     /locus_tag="angN"
                     /protein_end="704"
                     /protein_start="446"
                     /score="106.0"
                     /tool="antismash"
                     /translation="ELTPMQRAYLLGRTTQMPLGGVAMQETLEHRGTLSASSIRHRLST
                     MVVKYPCLRTFIDSKSLKLQVSQCPQVNLAHVDLRHLEKDKAEEELARFRYTYNHNMFD
                     LDQPLWNVTTFSLSETDTYVFSRFDALILDARSIASLLVELFDEQAPYIPSFDFEPDHE
                     HVQSARAKDEKYWLNKLATVEKSMCFPWHKPLKSISHSRYQRQSLKIEKETVKKLVRVA
                     GKEGLYKNTLMMSVAMEALSSHVCNGQLCVAVPVLP"
     CDS_motif       complement(15436..15474)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0011"
                     /evalue="3.50E-02"
                     /label="Cy3"
                     /locus_tag="angN"
                     /protein_end="583"
                     /protein_start="570"
                     /score="7.7"
                     /tool="antismash"
                     /translation="FSRFDALILDARS"
     CDS_motif       complement(15616..15651)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0010"
                     /evalue="5.20E-01"
                     /label="Cy7"
                     /locus_tag="angN"
                     /protein_end="523"
                     /protein_start="511"
                     /score="3.9"
                     /tool="antismash"
                     /translation="VSQCPQVNLAHV"
     CDS_motif       complement(15673..15708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0009"
                     /evalue="1.80E+01"
                     /label="Cy2"
                     /locus_tag="angN"
                     /protein_end="504"
                     /protein_start="492"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="VVKYPCLRTFID"
     CDS_motif       complement(15808..15837)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0008"
                     /evalue="1.10E-01"
                     /label="Cy1"
                     /locus_tag="angN"
                     /protein_end="459"
                     /protein_start="449"
                     /score="5.9"
                     /tool="antismash"
                     /translation="PMQRAYLLGR"
     CDS_motif       complement(16030..16074)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0007"
                     /evalue="8.50E-01"
                     /label="Cy7"
                     /locus_tag="angN"
                     /protein_end="385"
                     /protein_start="370"
                     /score="3.2"
                     /tool="antismash"
                     /translation="ISQGSHVALDSQVVS"
     CDS_motif       complement(16141..16167)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0006"
                     /evalue="1.50E-02"
                     /label="Cy6"
                     /locus_tag="angN"
                     /protein_end="348"
                     /protein_start="339"
                     /score="8.4"
                     /tool="antismash"
                     /translation="APVVFTSAI"
     CDS_motif       complement(16195..16239)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0005"
                     /evalue="1.60E-02"
                     /label="afterCy5"
                     /locus_tag="angN"
                     /protein_end="330"
                     /protein_start="315"
                     /score="8.4"
                     /tool="antismash"
                     /translation="LGHSRYDGVSMMRDL"
     aSDomain        complement(16300..17178)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angN_Heterocyclization.1"
                     /evalue="1.50E-72"
                     /label="angN_Heterocyclization.1"
                     /locus_tag="angN"
                     /protein_end="295"
                     /protein_start="2"
                     /score="236.4"
                     /tool="antismash"
                     /translation="ELTPMQAACWFGRKDNGQLGNVASHLYTEFDGENINIDKLNSALG
                     SLYKRHEMLRLKVNHLGESSIIDVPNHALLEIEDFTHLSPENMHKALIEKRQSWAHQML
                     DLTQGQVARFSVSLLPDNAFRLHIDSDMIAIDPDSCRVLIEDLAMLYESGASEVKNNPT
                     FFSWHGMAKNDPILKSQRKSDRAWWKSNLNNIAPSPSLPFFEPNTNKAESHHYSAWLDA
                     EQRTDLITLARKNNLTPANLMLGLFARTLGKATGDETFRINVPTFWRPPIIEGTESLVG
                     DFVNFVVLSVDM"
     CDS_motif       complement(16363..16401)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0004"
                     /evalue="2.00E-03"
                     /label="afterCy4"
                     /locus_tag="angN"
                     /protein_end="274"
                     /protein_start="261"
                     /score="10.9"
                     /tool="antismash"
                     /translation="FRINVPTFWRPPI"
     CDS_motif       complement(16762..16806)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0003"
                     /evalue="5.10E-02"
                     /label="Cy3"
                     /locus_tag="angN"
                     /protein_end="141"
                     /protein_start="126"
                     /score="7.2"
                     /tool="antismash"
                     /translation="RLHIDSDMIAIDPDS"
     CDS_motif       complement(17002..17040)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0002"
                     /evalue="2.80E-03"
                     /label="Cy2"
                     /locus_tag="angN"
                     /protein_end="61"
                     /protein_start="48"
                     /score="10.4"
                     /tool="antismash"
                     /translation="LYKRHEMLRLKVN"
     CDS_motif       complement(17140..17169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_angN_0001"
                     /evalue="4.20E-01"
                     /label="Cy1"
                     /locus_tag="angN"
                     /protein_end="15"
                     /protein_start="5"
                     /score="4.3"
                     /tool="antismash"
                     /translation="PMQAACWFGR"
     mobile_element  17317..18370
                     /mobile_element_type="insertion sequence:ISVA2"
     CDS             17396..18316
                     /codon_start=1
                     /note="ORF11"
                     /product="putative transposase"
                     /protein_id="AAA81776.2"
                     /transl_table=11
                     /translation="MPKPRYKTTNWKQYNKALINRGSLTFWIDEETIAEWKQNKQGKRG
                     RPRRFSDLAITTALMVKRVFSMPLRALQGFLDSVFKLANIPLVCPHYTCISRRAKEVEV
                     SFKTKTRGAIQHLAIDATGLKVYGEGEWKVKKHGTDGKRRVWRKLHIAVDTSTHEIVAA
                     ELSLSNVTDAEVLPNLLKQTRRKIIEISGDGAYDTRNCHDAIRIKQAVALIPPREGAAF
                     WEQGHPRNLAVGCQKLYGSNKKWKKRYGYHKRSLSETAMYRVKQLLGGKLSLRNYNAQV
                     GETYAMIKALNKLTGLGMPETQYIA"
     CDS             18437..19405
                     /codon_start=1
                     /note="ORF12"
                     /product="putative transposase"
                     /protein_id="AAR12532.1"
                     /transl_table=11
                     /translation="MKYTHLTENERYMISALRKQGISTAEIAKQLGRHKATIYREIERN
                     CRYNKFFDRYSYQPERAQQMARNRLSRSRRNKRYTKLDFRLPEALLRLDWSPDQIVGYL
                     RMRGYPTMSHELIYQHVWNDKALGGTLWKHLRQSTKQRRKRYNSKDSRGRLANKRHITE
                     RPANAEHRKEPGHWEIDTVVGRGTKHCIVTLVDRMTGYTFIGQMDDRTSESLNVRMSKI
                     MTRSDLPFKTITADNGTEFHGYAQLEKHHNCLFYFANPYHSWERGTNENTNGLIRQYLP
                     KRTSMSHVTQKLCNEIAHKLNTRPRKRLGYRIPLEYIHAHL"
     regulatory      19529..19533
                     /gene="angH"
                     /regulatory_class="minus_35_signal"
     gene            19529..20854
                     /gene="angH"
     regulatory      19551..19556
                     /gene="angH"
                     /regulatory_class="minus_10_signal"
     regulatory      19591..19596
                     /gene="angH"
                     /regulatory_class="minus_35_signal"
     regulatory      19614..19619
                     /gene="angH"
                     /regulatory_class="minus_10_signal"
     CDS             19652..20854
                     /NRPS_PKS="Domain: Aminotran_1_2 (59-343). E-value: 4e-08.
                     Score: 24.6. Matches aSDomain:
                     nrpspksdomains_angH_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="angH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 349;
                     E-value: 6.3e-106)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF13; involved in anguibactin biosynthesis"
                     /product="histidine decarboxylase"
                     /protein_id="AAR12533.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.7e-09, bitscore:
                     24.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFSPFRQRLIGNVMKLSNEDLCKLNKFWLYCEENQYFNVGYPES
                     AAFDYSILEKFMKFSINNCGDWREESNYKLNSFEFEKEVMRFFSQLFKIPYNDSWGYIS
                     NGGTEGNMFSCYLAREIFPTAYIYYSEETHYSVDKIVRLLNIPARKIRSLPSGEIDYQN
                     LVDQIQKDKQKNPIIFANIGTTMRGATDNIQRIQQDLASIGLERNDYYIHADAALSGMI
                     MPFVEQPHPYSFEDGIDSISVSGHKMIGSPIPCGIVLAKRHMVDQISVEVDYISSRDQT
                     ISGSRNGHSALFMWTAIKSHSFVDWQGKVNQCLNMAEYTVQRFQEVGINAWRNKNSNTV
                     VFPCPSEPVWRKHSLANSGSVAHIITMPHLDGPDKLDPLIEDVIYDLLPNYNILNVSGQ
                     N"
     aSDomain        19829..20680
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_angH_Aminotran_1_2.1"
                     /evalue="4.00E-08"
                     /label="angH_Aminotran_1_2.1"
                     /locus_tag="angH"
                     /protein_end="343"
                     /protein_start="59"
                     /score="24.6"
                     /tool="antismash"
                     /translation="SINNCGDWREESNYKLNSFEFEKEVMRFFSQLFKIPYNDSWGYIS
                     NGGTEGNMFSCYLAREIFPTAYIYYSEETHYSVDKIVRLLNIPARKIRSLPSGEIDYQN
                     LVDQIQKDKQKNPIIFANIGTTMRGATDNIQRIQQDLASIGLERNDYYIHADAALSGMI
                     MPFVEQPHPYSFEDGIDSISVSGHKMIGSPIPCGIVLAKRHMVDQISVEVDYISSRDQT
                     ISGSRNGHSALFMWTAIKSHSFVDWQGKVNQCLNMAEYTVQRFQEVGINAWRNKNSNTV
                     VFP"
     CDS             20970..22580
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 186.3; E-value:
                     1.6e-56)"
                     /gene_kind="transport"
                     /note="ORF14"
                     /product="putative ABC transporter"
                     /protein_id="AAR12534.1"
                     /transl_table=11
                     /translation="MINKISQHYVTPALIPALRPSLAKLTLGTLSEIVSAVAKIGALLC
                     LIQLIDDLSNQWVYGAIGLWIFSALLSSLSSWLVHNAESLFSARLRRQVAQHLTRLPSK
                     TLSRYGDNQLRRLVSEDINTLHHMVAHLPSEFVTFAIVPVMSITIMLNMAGPIALLTLL
                     PGLIASLYYLVFLPRFAAKYGAERMNIMGEIVTAVNDYTRGIRVNRVYGTQSGALASYH
                     GATQRFTNGIIKWVGSVALPASIAIALLQAVSTFAIAYSISYRLSPSAMASVFFFGLAV
                     VSPVLKLGHGLDYVTAGKNAAKNIGKLLKQTPIGCGNVNVGSKTLPLQASKISVINDTT
                     TIIDSFTHCFPTGSCTAIMGPSGIGKSTLLRILAGQEVPYSGTTMLGSYELSTLTEMSR
                     HMAIRYVPQDIGVLKTTVRQNLQLTAPNACDSEFFDALALAEVDINLDYDASLLSGGQQ
                     QRVALASIFLNQASIFLLDEPTSALDKKTALSIMKNLTEFAQKENKTIIMVTHDAELAQ
                     RADFILTLQKNAQLQDEEV"
     CDS             22577..24259
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 176.1; E-value: 2e-53)"
                     /gene_kind="transport"
                     /note="ORF15"
                     /product="putative ABC transporter"
                     /protein_id="AAR12535.1"
                     /transl_table=11
                     /translation="MTYQNTPSSKSNIPASAKYRLYRVGAGWALVAALEALTYTVLALS
                     LVKQAPPLGVISAAIVAILVTVLVTRAGFISGAQLAGDLYSAVGQSLSKAKLSWFNDQH
                     RTQLTQLAERGIPGFMSIPAHQLQTFLHTPLVPLFLIAGIGIVGGADVALISAVSLIGA
                     LLLQYKAQNHLSNSDSERHNADVQATKSTLELIDHLDLLRSTAGPERAIERIDQSWCTQ
                     EKVHSRINLTASMATLTSALATVFPLACVTIYLVVEGVTQPLLILGLLILITRAAAPLG
                     ELALAGFAINDVKSSIRDYNQLTNVPTLPEPKPENAISPNNYNFELNHVGYLDLFKDAN
                     VEIVQGEKVVINGVSGSGKSTLLGLFLRFDDPNQGHISLGGINLQNIPYDILIQHIAYV
                     AQDPIIFTGTLAENIRLGNPEASNAEVELFARQAQLSELIDLSGDGINQSVGQKGSRLS
                     GGERQRVAIARALIKKAPILILDEATSALDEVTEQKIAQQTQALGSTVIVVTHRDKKVW
                     HPTLELTIDKQRVNVLRLRTNSIQDYEKSAAPRLSRAISSRSF"
ORIGIN
        1 ttactgatga acggtttggc cagtcaaggt tactttcatt tgttggccaa tacttacaac
       61 ttgctttgcg ttataacgag ctgtttgata agtcacaatt aggcgcaatg tccgttcatc
      121 accaataacg ttttccatta tttcaaagtg taaaccaaac aacgatttgt tcttgtttgg
      181 aaggatttgt tgatatggaa ccggtatgtt attcggcgtt tgtagagaac catatagcgc
      241 attgtcagca tggatttgag catatacatc gaacagtaat ccattttttg gatccaaacc
      301 tagctctcgt tgtaccatat caataggtac agttgcatgt ggcattgagt cattgatggt
      361 catagttaca ttctcaatca atttgccaaa agattggtcc ggttcaaata taactcgatg
      421 ggcaaccatg gtcgtgaagt atcctactga atcaaaatat ttcgcatcat cacggcccga
      481 tgcagatgtt ccgatcacta agtcttttaa attccctgca ttatgtagag cttgtgctat
      541 tgcagaatac acaacgctga agatagatga attgtattct cttgctagtg agtgtacgga
      601 gtggtaagcg cttggaccta agtcaatttc tatccaattt gcttcaatcg ggtttacttc
      661 tggcccattt tgatctggtt ctgtgcaggt taagttaagg cctgaagttg agcctcgtaa
      721 gtggttcacc cagtaattga tgtcctctgc aattggacct ctattttttt gggcgagtgc
      781 ataatcatga atactatagg ctgatttatc ccactcaggc tcttgatttt gactgcgagc
      841 taaatatgca tcagaaagtt cggacatcaa attatttaat gaccattcat caataatcat
      901 atgatggatt aggaaagata aaacttgctg attagttttt ctatccttaa aaaatcgaat
      961 gcgaagtggt aactctttcg ataaatcaaa tacataagat gcttctgatt ctagactcga
     1021 ggtgccggat tctgcgctgc tccaaaacca tgagtactga attaagtctt tctcgtcaat
     1081 aacctgttgt atggaaccat cagtaccctc gttaaataaa gttcttaatc ctgtatgacg
     1141 aatcaacagg tctgaaaaag cgagtttaaa tacttcctcg tcaacttcag catcaaagcg
     1201 cattgcaaat ggcaaattaa aaatagcaca ctggccagtt gcgaggtggg cgttccataa
     1261 aaagctttgt gcaaatgaca atggtagctt actacctata gaggttgaac cgtgtgggag
     1321 agccatatct actggcttat tgcgtgacga cttatcggtt agcgatacgc agcgagcgag
     1381 tgcttgtgcg cttggtgatt tgaaaaagtc attaaagctg atttcaatat catggttatt
     1441 cattaagtta ccaatgattc ttgttgctaa taacgagtga ccacccattt caaaaaaatc
     1501 atcacctaac tcaacctcgg ggtcatcaag actggctctg aattcagaca gtattatttg
     1561 ctcgatgtta ttgttattgt tatcaatttt acttatatct aagtatattg gatttagctt
     1621 tgactcaaaa ttaagggtgt ttaaaaattc ataattagac tcaatattat taatgattga
     1681 tttgttttta aggtgtaagt ctaatatagg atgtgttgag attagtaagt atttttcttt
     1741 cccttcttgt aaaatgtcca ccccaaatgg cggttggaaa tctggctccc aaaggcgtag
     1801 ttttatatct gctacccggt ctgatagttt ttcaccttct acctgagcaa catttgttaa
     1861 cccctcacta tcaactgagt gccatttctc caactcaaat tcatctgaga atcgatagcg
     1921 cagatttaac tgtatgtcat ttaaaactaa cttttttaca gcttgtataa gctgttcatt
     1981 tttactattt atatcaatag tataagcgtc tactgtccat tctatgcttc ttggatcttg
     2041 aagctgctgt atccatacct cttcttcatg ttcactaatt gacagtaggg ttttaggttt
     2101 acttttgacg ttgttcatgt gagtcctgat tcttatctta gggtttctat gtggcgttgt
     2161 tgatcaaatc agtttgaggt tcaacgacgc catatttgac taatcgttag cttctaacag
     2221 gcatacctag tcctatgact ttgtttatag ctttgacatt cgccatgatt tctcccactt
     2281 gagcgttgta acatctcaag ctcaatttac cgctggttag tcctttatat cgagacattg
     2341 cggtctcaga tattgagcga tagtggtaac cagactcaga tttccactcc gttattgttc
     2401 cgtttttaag agcctctaca gcttcatttc tgggatgccc atcttcccaa agagccgcat
     2461 tatttcgagg tggtatcaac ggagtacagc ccttattttt cagagtctca tggcaacttt
     2521 ttgtgtcata tgctccatca gcagatactg tatggatctt tctacgtaaa gggttgagta
     2581 atgttggcag cacttcgtta tcgccaacac ttacaagact gacttctgca ctaatggtct
     2641 catgagtttc tatatcaaca gctaagtgca gtttgcgcca agttctgcgt ttttcggcac
     2701 cgtgcttttt cactttccat tcaccctcgc caaaaacttt gagacccgtc gagtcaatgg
     2761 ctatatggcg aatagctcct ttggacttat tgcgatattt gacctgaact gtcttcgacc
     2821 gtttactgat acaggtgtag tcaggggacg tcagtggagc atccaatagc tcaaagatag
     2881 aatcaataaa gccttgaaga gcacgtaatg gcagagagaa gatcccctta atcatcaagg
     2941 cagtttcaat cgcggtatca gaatactgga aacctctacc acgcttacca tgatgggttc
     3001 tacatcgcca tgcatctatg gctgaatcat ctatccaaaa cgtaaccgag ccacgcttgc
     3061 acagagcctt attgtattcc gcccagttag ttatcttctt tttcgcttta cccatgtcac
     3121 caccgttcta accaccataa aggatcagat cacaggactt ggaaaaggtt caactgattt
     3181 aagcaacaac gcctttctat gttgtcgatc ttatttttat aaattatgcg ttaatttgct
     3241 tacacatcaa gagtaatagt gatagcattg attatcattt agatttacat tttccgtcaa
     3301 gttaataatt ttattaagtt taacgatgta tttataactg ttgaggctct gctaaatccc
     3361 tgctgtgacc ctaattaatt tacatctgta gtagctctaa aaattttgag agtttagttg
     3421 tgaccttatt ttttattaaa aagaaacata gttaccattt tttagaattc gacattttct
     3481 ttatgataat tctattttat gagtacttca ttctatttga tttttccctg aatttagatg
     3541 cgtctcaata ttcctactat tctggagagc attctaaatg acttttcgta tgattctggc
     3601 gttctttact ttgtgcgcta catctctttt ttttggtgcg aaccagatcg agtggtcatt
     3661 attgccgacg tttaatgaga aagcttggtt gcctattata gccagcaggc taccaaggct
     3721 agttgctctg attcttacgg ggtccggctt ggcgatgtgc ggcgttattc tccaacacat
     3781 cgttagaaat cgttttgttg aacctggaac tacaggcagc cttgatgcgg ccaaactcgg
     3841 tattttggtt tcaatcgtga tgctgccatc atcagacaaa ttggaacgta tgttctttgc
     3901 tgtcctgttt tgctttgccg ctggcttggt ctacatcgct ataatacgta aggttaagtt
     3961 cagcaatact gcgttggttc cagtgattgg cttgatgttt ggtagtgtac tcagtgcact
     4021 tgctgaattt tacgcctatc aaaacaatat tttacaaagt atgtctggct ggttgatggg
     4081 ggacttctcc aaagtggtcc aagagcatta tgaaatcatt tttttgatct tgcctataac
     4141 cttattgacc tacctctatg ctcatagatt tacagtgatg gggatggggg aagatatagc
     4201 ctccaatttg ggcatcagct acgccatgac cgccgcatta gggttgatac tcgtttcaat
     4261 cacggttgca gtcacagtag tgacggtggg cgccattcat tttgttggct tagttatccc
     4321 taacttagtg gcgctaaaat acggcgacca cctcaaaaac actttaccta ttgttgcatt
     4381 gggcggtgcc tcgctactga ttttttgcga tgtcattagt cgggttgtgc tttttccgtt
     4441 tgaagtacca gtaggtttga ccgcaagtgc cgtaggtgga gttatgtttc ttgccttttt
     4501 gcttaaggga gcaaaagcat gacatcactc aacttaaact ttcgagtgag tgttgtactc
     4561 gtgatcctgt tatctatcgc ttttattttc attaattcag ggtttgacct tgagtacatc
     4621 atcccaagaa ggctcattaa actcagtgcg atcataatcg ggggaagttg tgtggctatc
     4681 tctgctgtca tttttcaagc cttggccaga aatcgcatat tgacgccatc tattatgggt
     4741 tacgagtcca tttatcttgt atggcaagct ctgctcttat tatttgttgg cacctctggt
     4801 agtgcagttt tgggtgtggt aggtaatttt gtcgtatcag cggtactcat tttgttgtac
     4861 tcattcgtta ttcaattctg ggtgctcaag cgatttcaac atgatatgca tcaagtgttg
     4921 ttgattgggt ttgtgctgac catggtgctg acaacggttg ctcaatttat ccagattaga
     4981 ataagtcctg gagagttctc tattttccag gggttaagtt acacctcgtt tgaaagagcg
     5041 aagccgtcca cacttttatt tgctggcacg gtgttgagta ttctcgccct ctttgccaat
     5101 aaatgggtga gtgagctaga cgtgattggg ttaggacgag atcaggcaat gtctttaggg
     5161 ctcaacgatg cgcactatat tcctaaatat ttttctgtca tcgcaattct tgtggccatc
     5221 tctactagct taattggacc aactgcgttc atgggggttt tcattgccaa cattgcttat
     5281 tccatcacgg gttctccgca atacagacac accttaccgg ttgcttgcac catcgctatt
     5341 gtgatgtttt taactgctca attgatggtt gaacactttt ttaattataa aacaacagtc
     5401 tctattttgg tcaacgtcct ttgtggcggg tacttcctta tcatcacgat gagagcaaga
     5461 agccagctat aaagtctgtt catcgcctgt ttattggcaa cttactgaaa cataaggaaa
     5521 tccccatgtt taagagcacc ctaaatattg ctgtcgcgat cgtctgtagc tctcttgtaa
     5581 ccttaacggg ttgcgaacca aaagtggctc aatctcaagt tattcaacca ttagaaaccc
     5641 ccatcgtgat tgaacataat ctaggtcaaa ccgtgatttc aaatcgacct cagcgagtgg
     5701 cagctctcga tatgaatgaa gtggatttct tagatcagtt aaacgtacct attgcaggta
     5761 tggtgaaaga ttttgtaccc cactttttgg aaaagtataa aaacactcct gacatttcgg
     5821 accttggagc aatcgttcaa cccaacatgg aaaaaatcta tgctcttaaa cccgatctag
     5881 ttttgatgac cccactgcac gccaatcagt atgaagaact gtctaagctc gcaccaacgg
     5941 tacactttga tattgatttc cgtaacagtc atgggcatca cgtcgacata atcaaacagc
     6001 acgttattga tctcggtgaa atctttaata aacaaacact cgctcaaaag aaagtggctg
     6061 aaatcgatgc caaggtcgat gaggttcaag ccttgacggc cgaacgctca gaaaaagctt
     6121 tagttgtgat gcataacaat ggctctttta gctcatttgg tatcgagtct cgatatggct
     6181 ttgtcttcga tgtactgggt gtaaaacctg cgagtactga aattgcagcc agtttacatg
     6241 gccagcctat ttccagtgaa tttattaatc aagccaaccc tgacattctt tacatcattg
     6301 atcgcacagc ggtcatggaa ggcaagccgg ttattgatgc ggaacatttg gcaaaccctc
     6361 ttcttcgaca aaccaaagca tggaaaaacg gcaaagtaat ctttgtcgat gctgacgcct
     6421 ggtacatcac ttctgccagc atcacatcac tgaaaatcgt gattgacgac attataaaag
     6481 gttatcagag ctagatttca aaacaataag ctagaccaac gtagtccagc aaaaaaccat
     6541 cactgctttc cagtgcggat gtgagccagc ctaaaacagg ataaaaagga atcaaccatg
     6601 actcatcagg tagcgacctg tcataaaaaa caatcattta gtggtaaacc aactctaagt
     6661 cgtatcgctc ttttggtcgc gcttcagatc agcgcgtctg cattgcccat cagtatcact
     6721 cacgctgaag agcaggccga cgaatctatc accgtttacg gccaagccaa tgaggcgtat
     6781 gcggcaggta aaatctcaaa ggcgagcagc atagggatgc tcggcgataa agacttccta
     6841 gataccccat ttaatgccat tgggtacaca gacaaacaca ttcaagacca acatgcacaa
     6901 gatatatccg atgtaatatc cgcgtctgat ccttctgttt ttaccagtgg ggaaaccggg
     6961 ttaaacaaag aaagctttaa gatccgaggt ttcagttcgg atattggcga tgttatgttc
     7021 aatggtttat atggaatcgc tccttactat cgtagctctc cagagatgta ccaacgcatc
     7081 gatgtactga aaggcccggc ttctttgctt aatggtatgc caccgaacgg ttcagttggc
     7141 ggttcgatca atttggtgac taaacgagct caagaagcac caatcacatc ctttactggc
     7201 acttatatgt cggattctca atttggcggt catattgata ttggtcgccg ttttggtgaa
     7261 aacgaacaat ttggggttcg ttttaatggg gttttcagag atggggatgc gtcagttgat
     7321 ggtcaaagtc gtaaagcgca actcgcatcg ctgagccttg attggcgtaa tgatattgcg
     7381 ttgattgaag ctgatttata ctttagtaca gagcgagttg atggtccaaa tcgaggtttg
     7441 agcatagctt ctggcgttga cgtcccgtcc cccccttcgt cagatacctt actcagccct
     7501 agttgggcat acaatgacag tgaagataaa ggcatgatga ttcgtgctga actggatttg
     7561 agtaattccg taacagctta cggtgctgtg ggtgccagtc gtacagactt tgattctaat
     7621 gtaccacaaa gagttaaaat catcgacgac agcggaactc ttgaggtgtc tcttggctcc
     7681 gttaagttag aaagcaaacg cacttccggt gaggtaggga ttcgtagcag ttttgacaca
     7741 gggcctatag agcactattt ggtgcttaat agtacctact ttagagaaga taaaaatgat
     7801 tctccgacag ggaacaataa tcctgggtcc tggaatccta atatatataa cccagtgtgg
     7861 gggcctgaag attccacata tgacaactat tatgaattac cggtcgattc cacacagatc
     7921 agctttggtg tagccgatac cttatcttta gctaatggca aataccaagt cacattaggt
     7981 ttacgtcatc agagtattga ttatgaatca ggtgttactt ggaatggaaa tgcttttcct
     8041 accacaaagc ttaaggaaag tacctacaca ccggctattg ttgcgttgta taaagtttct
     8101 gactcagttt ctctttacgg taactatacc gaaggcctaa caaacggaaa aacggcaggc
     8161 tcgggggccg ctaacgtggg tgaagcgttt gaaccacaaa aaaccaagca aacagaagcc
     8221 ggcttaaagc tcgatatgaa cgactttgct catactttta gcttgtttga gatcaaaaag
     8281 cccaacggat accaagaccc agacactaac atttactctt ttggtggcga gcaacgtaat
     8341 cgaggtattg aatgggggtt ctacggtacg gtgttagagg actacacgct gactggtggt
     8401 atcgcttata ccgacgcaga gatcactaaa gcaacagatg tcacgactga aggaaagcaa
     8461 gcgactaagc tacccgatct tcaagctaag ttagcattgg aatggaacct accagtgatg
     8521 cgtcaactta ctcttattgg tcaagcaaat tacatgtcag agcaatatat tgatgcacaa
     8581 aacactcaat cactgtctgc acagactatt tttgatttag gtgctcgcta taactctacc
     8641 atcgccaatc aaagtgtcat ttggcgtctt gcggtcaaca acgtaaccga tgaagcatat
     8701 tggactacca cccattacgc tagccttgcg ttgggtgccc ctcgtacggt gatgctatct
     8761 gctacagcgg atttttaatc tcggtcaatt ttgcccttga cctttctggt taagggcatc
     8821 gtcttcccct tccccccatt tggcttttta tgagaattta gaatgaatca aaatgaacat
     8881 cccttcgctt tccctgagac aaaattacct ttaacctcca atcaaaattg gcagttatca
     8941 acccaaagac agcgtactga aaaaaaatcg attaccaatt ttacgtatca ggaatttgat
     9001 tacgaaaaca tttcgaggga tacattagaa cgctgcctca caacaataat taagcatcac
     9061 ccaatattcg gagctaagct cagtgacgac ttctacctcc attttccgag caaaactcac
     9121 attgaaacct ttgcagttaa tgacttaagt aatgccttaa aacaagatat tgataaacag
     9181 ttggccgata cgcgttctgc agtaacgaaa agccgctcac aagcgataat ctctatcatg
     9241 tttagtatat tgccaaaaaa cataatcagg cttcatgtac gcttcaactc agttgttgta
     9301 gataatccaa gtgttacgct tttttttgag cagcttactc agttattatc gggaagtccc
     9361 ctttcttttt taaatcaaga acagactatc tccgcataca atcacaaagt taataatgag
     9421 ttgcttagtg ttgatcttga gtccgcaaga tggaatgaat atattctaac actacctagt
     9481 tcagcaaacc ttcccacaat ttgtgaaccc gaaaaactgg atgaaaccga tatcactcgc
     9541 aggtgcatta cactgtcaca aaggaagtgg cagcagttgg ttactgttag caaaaaacat
     9601 aatgtcacac cggagataac tcttgccagt atattttcga ccgttttatc actctggggg
     9661 catcaaaaat acctcatgat gagatttgat atcaccaaaa tcaatgacta cacgggcatc
     9721 ataggccagt ttaccgaacc tttattagtg ggtatgtccg gctttgagca gagctttctt
     9781 tctcttgtta aaaacaacca aaaaaagttc gaagaagctt atcattatga cgttaaagta
     9841 cctgtttttc agtgtgttaa taaattatct aatatttcgg attctcaccg ttatcctgct
     9901 aatatcactt tttctagcga gcttttaaac acaaaccata gcaaaaaagc tgtatgggga
     9961 tgtcgtcaat cagccaatac ttggctttct ttacatgctg taatcgagca agaacaactt
    10021 gtcttacaat gggacagcca agacgcaatc ttcccaaaag acatgatcaa agatatgtta
    10081 catagttaca ccgatttatt agacttactc agccaaaaag atgtcaactg ggcacagcct
    10141 ttaccaactt tgctgccaaa acatcaggag tccatacgca ataaaataaa tcaacaggga
    10201 gacctagaac taactaaaga actcctccat cagcgttttt ttaaaaacgt agagtccacc
    10261 cctaatgctc ttgcgattat ccatggtcaa gagtcattag attatataac tttagcaagc
    10321 tacgccaaga gttgtgcggg tgcactaacc gaagctggag taaaatcagg agaccgcgtt
    10381 gctgtcacta tgaataaagg cattggtcaa atagtggcag tattgggaat attatatgct
    10441 ggggctattt atgttcctgt ctctctagat caaccacaag aaaggcggga aagtatttat
    10501 caaggtgctg gaattaacgt tattcttatt aacgaatcag atagtaaaaa ttccccttca
    10561 aatgatcttt tctttttcct ggactggcaa acagcgataa agagtgagcc aatgcgtagc
    10621 cctcaagatg tcgcgccaag tcaaccagcc tatattatct acacatcagg ctcaacagga
    10681 acccctaagg gagtggtgat ttctcaccaa ggcgctctta atacatgtat cgcgatcaat
    10741 cgacgttatc aaattgggaa aaatgatcga gtattggctc tttcagcact acattttgac
    10801 ctttcggtat acgacatctt tggcctactt tctgccggcg gcactatcgt attagtcagt
    10861 gagcttgaaa gacgtgaccc gattgcttgg tgtcaagcaa ttgaggagca taatgtcacc
    10921 atgtggaata gcgtcccagc attatttgat atgttattaa cttacgctac ttgctttaac
    10981 tctatcgctc cctcaaaact ccgtttaacc atgctttcgg gagactggat tggattagat
    11041 ttaccgcagc gttatcgcaa ttatcgtgta gatggccaat ttattgcgat gggaggagcc
    11101 accgaagcat cgatatggtc aaacgtcttt gacgtagaga aagttccgat ggagtggcgc
    11161 tctatccctt atggctatcc tctacctaga caacaatatc gagttgtcga tgacttgggg
    11221 cgagattgcc cagattgggt agctggcgaa ctttggattg gtggtgacgg tatcgcactg
    11281 gggtattttg acgatgaatt gaaaacgcaa gctcagtttt tacatattga tggccatgct
    11341 tggtatcgta ctggtgacat gggctgttat tggccagatg gtactcttga gttcttgggg
    11401 cgaagagaca agcaggtcaa agtaggaggt tacagaattg agttgggaga aatcgaagtt
    11461 gcactcaata atataccggg ggtgcagcgt gcggttgcta tcgcagtggg caataaagac
    11521 aaaactctag cagcattcat cgttatggat tcggagcaag caccaatagt tacagcgccg
    11581 ttggatgcag aagaagttca acttttgttg aacaaacaac tgcctaacta catggttccc
    11641 aaacgcataa ttttccttga aaccttcccc ctaaccgcta atggtaaagt cgatcataaa
    11701 gctctaactc gaatgactaa ccgagaaaag aaaacatctc aaagcataaa taaacctatt
    11761 attactgcga gtgaagatag agtagccaaa atttggaatg acgttcttgg tcctacagaa
    11821 ctctataaat cgagtgattt ctttttgtcg ggaggagatg catacaacgc aatagaggta
    11881 gtcaaacgtt gtcataaagc tggctatcta atcaagctat caatgttgta ccgttattct
    11941 acgattgaag ctttcgctat tatcatggac cgttgtcgat tagcacctca ggaagaggct
    12001 gagttatgag ccctttaatc aaacttgcag cctcttcgag gctgcatgat gcaactcatt
    12061 atgttttatg cccttttgca ggaggtggta gtggtgcatt tagacactgg cgtacattat
    12121 cccttgaaaa tgaagtgatt tcggtaatgc tttatcctgg tagagaattt cgtatagacg
    12181 acccaacagt cataaacatc ggcacattag cagaagaaat gatccaagct ttaaaaacct
    12241 gtaatcaacg aatagaagat acgatcattg tcggtcatag tatgggcgcg caagtggcgt
    12301 atgaagcaag taaaaaacta gtaaatcagg ggctatttct gaaagggctg atcatctctg
    12361 gttgtcaagc tcctcatatc aaagggcgaa ggttactagg tgaatgcgat gataaaacct
    12421 ttattcataa tctagtcgag attggagggt gtgatccaag tttagctaaa agtccagagt
    12481 ggtggccgat atttctgcca gctttgaggg cggactttac ggctacagaa cagtatattt
    12541 tcacatcact tccaaatgat aaggaaggcc ttcctatccc aactctattg atttcaggtg
    12601 atcaagatag agaagctaac ttttcagaaa tagaagagtg gaaactttgg tgtaataaag
    12661 tcgttgatca tttagtggtc gagggcgggc atttctatat aacagagcaa cctcaaatga
    12721 tgcttgaatg catccgggct ttatcaaccg aaacgactgc ctaatactaa ggttcggttg
    12781 atagattttt agacaaacaa cttcaaacga caagggtatg catttaagca atgcataccc
    12841 tgggcttttc gatcaacact attacttggt ttccggaatt ccataactct ggaatgctga
    12901 actttctggc aatcgataaa tttgcttacc taatacttgg ttaataatag aagcgtttct
    12961 gtaagcaccc atcccaagat ctggaccacc aaccccatgt tggaaaatct ccggattttg
    13021 tacaaagaca cgcccaacac cttggtcaca gcgttgagct ataaaatctt tttcaacaat
    13081 caagtctcca tgttcatctg tagccaagac tgaacctttt agatcattca accacttagg
    13141 ccattggtga gcatatcctg tggcacaaat cactgcatta gtacggaggt gaaaagtttg
    13201 ctcttgttgc gattggtagc attggacttc catctcctgg ttattaacag atataaccac
    13261 ctcgttgact tgactatttg aatataagct aagccctggt gaacgcccac caatagaacg
    13321 ttcgtatagc aaatcaaaaa tctcagcgat agtgtaccca ctaatccctt tgtaaagctg
    13381 tccttgacct tctacgatac tgcgacgttt ttcacgcgaa agagtatgga aataatgcat
    13441 atatgcagga gtaaagcatt cttgtcctaa cttagaagcc tccattggat ggaaaccagc
    13501 agaacgagtt acccagttga cccttgcccc ggcttctatt tgttcaagag ataaatcacg
    13561 gtataagttg agtacacact cagcggcact ttgaccggag ccaactacgg taacactatt
    13621 acacttggcc agctgctctc gcatgtgacc aaacctagcg gaatgttgaa ccaaagagtg
    13681 attcgtactt tttgcccatt gaggtaacca agggatggta ccgacaccaa tagacaagtc
    13741 tcggctatat cgcgtcttaa cttccccttc gtttaactga ctctgaatag taaagcattc
    13801 aatatccttt aagtacttta catctacaac agtttcacca taagcacaat tttctaattt
    13861 acctgcagcc cactggcagt aatgattgta ttcgcttctt ggcactagaa aagtttcgta
    13921 ataataaaat tggtataatc tgtcgtgttg tttgaggtaa tttaaataac ttaaagggtg
    13981 agttgggtct gccatagtga caaggtcagc taaaaatgga acttgcaatg ttgcgcccgg
    14041 aagcagcatc ccgctatgcc aattgaactc ttgtctacgt tcgatgaact caacatcaag
    14101 ttcagggtga tgagaagtta gagctgccaa ccctaaatta aacggcccta taccaacacc
    14161 gatgatatct tttattattg tattcactat ttatccttgc tatgagatta aaatattata
    14221 gtcatcaggt gacctaaacc tcagggattg atttacccta acaagtcacc ttcttttgga
    14281 aagttcgtgt caaatttaca aaccagctta tatctaaaaa tcaacaacct gctgtaaagc
    14341 gagatctttt acatcgtcag catttcggca acgaataagt tgcattactg gcaaatccac
    14401 ttgcaactcc ttattgaggt ctatactgat ttgtttaagg tgactaggcc ttagtcccaa
    14461 ttgagaaaaa ggtaggctgt cgctgtcaga attatttttt tctttaccaa taacttggca
    14521 gtaaatatca aagatctttc gcttagttaa atcaatgtcc caactttcgt ttggatctcg
    14581 atctaccaac tcgacaactc gagaccgacc aataggtaat agcttatgcg actgaaccac
    14641 atattgagaa gtctcaacca tgtgatctaa aatcatgtca atacgatcca atattgcctt
    14701 cactaaatca tctgcaactg cttcactggc ataatcaaca ctgaacatga ttgagcctcc
    14761 cgtaattgca acaaaacgta tatccattgc aacttgtggg gtttgcgtca aacctcgttg
    14821 aagggtcatt gacgcatcgt cacttaaaac tggccatgac aagccattag taatgacgat
    14881 tggaagagct ggtgccggcc cacaccgttc aaatagaact cgagctaaat cgacccccga
    14941 aaaagccaaa tgctcaagac cttctaaagt atctacctgt aaagtttttg ctcgctgaag
    15001 aaagtcatac tgatgagcat tccactgtgt aacaataaaa ctcgactgac ttgcataatt
    15061 agcactcgtc attggtagta cgggtactgc aacacaaagc tgaccattac agacatgaga
    15121 agacaacgcc tccattgcaa ccgacatcat cagagtattt ttgtataacc cctccttccc
    15181 agcaacacga accaattttt ttacagtttc tttttcgatt ttcagactct gcctttgata
    15241 tcgagagtgc gaaattgatt tgagaggttt atgccaaggg aaacacatcg acttttcaac
    15301 agtagccagt ttattcagcc agtacttttc atccttagcc cgtgcacttt gcacgtgttc
    15361 atggtccggc tcaaagtcaa aagagggtat atatggtgcc tgctcatcaa atagctccac
    15421 taataaagaa gcaatggagc gagcatcaag aattaatgca tcaaagcgag aaaatacata
    15481 agtatctgtt tcagaaagag agaaggtagt gacattccat aacggctgat ctagatcaaa
    15541 catattatga ttatatgtat atctgaaacg agctaactct tcctctgcct tatctttttc
    15601 taagtgcctt aagtccacat gtgccaaatt aacttgagga cattgactta cctgtaactt
    15661 aagcgattta ctatcaataa atgttctcaa acaagggtac ttaaccacca tggtagataa
    15721 ccgatgacga attgaagaag cagaaagagt ccctcgatgt tccaaagttt cttgcattgc
    15781 aacgccacca agaggcattt gggtcgttct gcctagtaag taagctcgct gcattggagt
    15841 caattcagac tcaaaatgag agaggcaaac taatttaggc tgcaacttat ctaatggtgc
    15901 tactagtaag tcaggagtcg aaataacgct tttagttaaa gcgacaaaat tctcaaacat
    15961 tgccgacgtc cattctttag gtaaagcttc ttgacgaaca tcccaattga tcatgattcc
    16021 gccatcaata ctcacaactt gtgaatcaag cgctacatgt gagccttgag aaatcgtcca
    16081 gtccattttg ccaaaatgtt tatggacacg acgagaaaat agattcccac taggtaaatc
    16141 aatcgcagaa gtaaagacga ccggcgctaa ctgagtgcag ccatgatgta aagaaaggtc
    16201 tctcatcata ctcacaccat catatcgact gtggccaagt aaaagtccca ttttatctgc
    16261 gaccatatga caaaactcaa ggagagtctt agactctttc atgtccacac taagaacaac
    16321 aaaattgacg aaatccccga ctaagctttc ggtcccttca atgattggcg gtcgccaaaa
    16381 tgttgggacg ttaattctaa atgtttcatc tccggttgct ttacctaatg tcctggcaaa
    16441 caagccgagc atcaaattag ctggcgtaag gttgttttta cgagcaagag tgatgagatc
    16501 agttcgctgt tcagcatcta accaggccga ataatggtgg ctttcagctt tattagtatt
    16561 gggctcgaaa aaaggcaatg aaggagaagg agctatatta ttcaaattcg atttccacca
    16621 cgccctatcg gatttcctct gagacttgag aatagggtca ttttttgcca tgccatgcca
    16681 agaaaaaaac gtcggattgt tcttaacctc ggaagctcca ctttcgtaaa gcatcgctaa
    16741 atcctcaatt aaaactcggc aactatctgg gtcaatagca atcatatcgc tatcaatatg
    16801 taagcggaat gcattatcag gtaataaact aacggagaat cttgcaactt gcccttgcgt
    16861 caggtcaagc atttgatgag cccagctttg tcttttttca atcaatgctt tatgcatatt
    16921 ctcgggcgat agatgagtga aatcttctat ttctaaaaga gcgtgattag gaacatcaat
    16981 aatagaactt tcgcctaaat ggtttacttt cagccgcagc atttcatgtc gtttatataa
    17041 actccctaat gctgagttga gtttatcaat attaatattt tcgccatcga attcggtgta
    17101 aaggtgagaa gcaacattgc ctagttgccc attatctttt cttccaaacc aacatgcagc
    17161 ctgcattggt gttaattcac tcatcagctt tcactttgtt gacaattcat ttgttaggcg
    17221 ccattatttt gcaaacgata atcatttaca ataaaaacct tattattaac tagataagag
    17281 acttggattc aagtacgaag tgcgacacct ctgaacggct ttgttgctta aatcgatgga
    17341 actaaatcta gaagctacga tctgatcggc tacacccatc aatcgtcgta gcctcatgcc
    17401 taaacctcgt tacaaaacaa ctaactggaa acagtacaac aaagccttaa tcaaccgtgg
    17461 ttctctgacc ttttggattg atgaggaaac gatagctgag tggaaacaaa acaaacaagg
    17521 caagcgtggt agacctcgtc gattcagcga cttagccatt actacagcac tgatggtaaa
    17581 acgcgttttc tctatgccgt tgagagcgct acaaggtttt ctagactctg tatttaagct
    17641 ggctaacatc ccgcttgttt gcccgcacta cacctgtata agccgccgag ctaaggaagt
    17701 tgaggtttca tttaaaacca aaaccagagg agcaatacaa cacctggcaa ttgatgccac
    17761 tggcctcaag gtttatggcg agggtgaatg gaaggtcaag aagcatggta ctgatgggaa
    17821 gcgcagagtc tggcgtaaac tgcatattgc agtagataca agcactcacg aaatagtcgc
    17881 agcagagctg agtttatcta acgtaaccga tgccgaagtg ctccccaact tactcaagca
    17941 aacgcgtcgt aaaataattg aaatatcagg tgatggtgct tatgacacaa ggaattgtca
    18001 tgatgcgata aggattaagc aagcggttgc gcttatccca ccacgagaag gggctgcatt
    18061 ctgggaacaa gggcaccctc gtaatttagc agtaggttgt caaaagctct acggctccaa
    18121 caagaaatgg aaaaagcggt atggctatca taagcgctca ctatcagaga cagcaatgta
    18181 ccgagtaaaa cagctgctag gtgggaaatt aagcctaaga aattacaatg ctcaggttgg
    18241 cgagacttac gctatgatca aagcgctgaa caagcttaca ggacttggta tgcctgaaac
    18301 tcagtatatt gcttaataac tgaacaactt tgggctgcca tgtcttacaa ccgaattaag
    18361 caacaaagcc cctctgaaca taaaaacagt aaggtgcgat aatcatgaac tttgctcccg
    18421 ccaagaagta aaaaacatga aatacacgca cctcactgag aacgaaaggt atatgatttc
    18481 tgccctcaga aagcaaggaa ttagtaccgc tgaaatagct aaacaactgg gtcgtcacaa
    18541 agccactatc tatcgagaaa ttgaacgcaa ttgtcgttac aacaagttct tcgataggta
    18601 ctcttatcaa ccagagcggg cacagcaaat ggcgcgcaac cggcttagtc gttcacgccg
    18661 aaataagcgc tataccaaac ttgacttcag gctacctgaa gccttgctac gacttgattg
    18721 gagtcctgac caaatcgtcg gatacctaag aatgagaggc tatccaacaa tgagccacga
    18781 gctcatttat cagcacgttt ggaacgacaa agctctcggt ggaacactat ggaaacacct
    18841 acgccaatct actaagcaaa ggcgtaagag gtacaactca aaagacagcc gaggacggct
    18901 tgcaaataag cgtcatatta ccgaaagacc agcgaatgct gagcatcgaa aagagccggg
    18961 gcactgggaa attgataccg tcgttggccg cggaaccaag cactgtatcg tgactttagt
    19021 cgacagaatg actggctaca cttttattgg gcaaatggac gatagaacaa gcgagtcgct
    19081 caacgtaaga atgagcaaaa tcatgacccg ctctgactta ccttttaaga cgataactgc
    19141 ggataacggc actgaatttc atggttatgc acaactagaa aaacatcata actgtctgtt
    19201 ttactttgca aatccatacc actcatggga acgaggcact aatgaaaaca ccaatggctt
    19261 gatacgacaa tacttaccga aacgaacttc tatgtcacac gtgacacaga agctctgcaa
    19321 tgaaattgca cacaaattaa atacgcgccc acgtaaaaga cttgggtata gaataccact
    19381 ggagtatatt catgcgcatc tgtagaaagt gtcgcacttc aaacttgata ctaagagaaa
    19441 tacgtcactt aacacgctct attcaggtca gaaaaaataa gaaacaccac cacatagtgg
    19501 catagtcatc agtatgcaca tcaaagactt gacaaataca aaatcaggag ggtaattgaa
    19561 acattcccta aatagttggc tttattaaaa atgaccaaaa aaacatgata attataaata
    19621 gttaaataag ttcagagcgc atgataatca catgctcttt agtccatttc gacaacgatt
    19681 aataggcaac gtaatgaagc tatctaatga ggatctctgt aagcttaata aattctggct
    19741 ttactgtgag gaaaaccaat attttaatgt tggttaccct gaatcagcag cttttgatta
    19801 ctctatacta gaaaagttta tgaaattctc catcaataat tgtggtgact ggcgagaaga
    19861 gagtaattac aaactaaact ccttcgaatt tgagaaagaa gttatgcgtt ttttctccca
    19921 attatttaaa ataccgtaca acgacagttg ggggtatata tcaaatggcg gtactgaagg
    19981 aaacatgttc tcgtgttact tagctcgtga aatttttccg acagcttaca tttattactc
    20041 tgaagagaca cattactcgg tagataagat agttcgatta ctgaatatac ctgcaaggaa
    20101 aatacgttcg cttccgagtg gagaaattga ttatcaaaat ctagtagatc aaatccaaaa
    20161 agacaaacaa aagaacccta ttatattcgc taatattggc actacgatgc ggggtgcaac
    20221 tgataatata cagcgaattc aacaagatct cgcgtcaata gggttagaga gaaatgatta
    20281 ttatattcat gctgatgcag ctctcagcgg aatgatcatg ccatttgtag agcagccaca
    20341 cccttattca tttgaagatg gtattgactc aatcagcgtc tctgggcaca aaatgattgg
    20401 atcccctatt ccgtgcggta ttgttcttgc caagcgacat atggttgacc agatttcggt
    20461 agaagtcgac tatatctctt cacgggatca aactatcagt ggctcaagaa atggtcatag
    20521 tgccctattc atgtggacag caatcaaaag tcattcattc gtagattggc aaggtaaagt
    20581 aaatcagtgc ttgaacatgg ctgaatatac tgttcaacga ttccaagagg taggaattaa
    20641 tgcttggcgt aataaaaact ccaatactgt tgtatttcct tgcccttctg agcctgtttg
    20701 gcgaaaacac tctttagcca attcgggcag tgtggcacac attatcacca tgccacacct
    20761 cgatggtccg gataagttag atccactcat cgaagacgtc atttacgact tgctccctaa
    20821 ctacaacatc ctcaacgtca gcggtcaaaa ctaacaacaa tattctatca acctcatttc
    20881 aataggcttt atatgaaata tcgagagagc tcaataagct caccaaaact cactctatct
    20941 caactttgtg ggttaactag ggtgagaaaa tgataaataa gatcagccaa cattacgtta
    21001 caccagcctt aataccagcc ttaagacctt cattagcaaa acttacttta gggactctaa
    21061 gtgaaattgt ttctgcagtg gcaaaaattg gtgcattgct atgtttaata caattaatcg
    21121 atgatctatc taaccaatgg gtttacggag ccatcgggct ttggatcttt agcgcattgc
    21181 tctcatcttt gtcctcttgg ttagtacaca atgctgaatc tctattttca gcaagattac
    21241 gtcgtcaggt ggcacaacac ttaacgcgcc ttccaagcaa gactctctct cggtatggtg
    21301 ataatcaact tcgccgcttg gtttcagaag acatcaatac tttacatcat atggttgctc
    21361 atctgccttc agagtttgta actttcgcca tcgttccggt aatgtccatt accattatgc
    21421 taaatatggc tggtcctata gcgctcttaa ccttactccc tggccttatt gcatcattat
    21481 actacctagt ctttctgcct agattcgcag ctaaatatgg tgcagaacgt atgaacataa
    21541 tgggagaaat agtcaccgca gtaaatgact acaccagagg aattagagtt aaccgggttt
    21601 atggaactca atcaggtgcg ctcgcgagtt atcacggggc aactcaacgc ttcactaatg
    21661 gcattataaa atgggtaggg agtgtggcac ttccagcttc catcgctata gctttacttc
    21721 aagcagtttc tacttttgct atagcttatt caatttctta ccgactaagt ccatcagcaa
    21781 tggcttctgt gttttttttc ggcctggctg tcgtttcacc agtattaaag cttggtcacg
    21841 gattagacta tgtcactgca ggtaagaatg cagctaagaa cattggtaag cttttgaaac
    21901 aaacacctat aggttgtgga aacgtcaatg taggttcaaa aacacttcct ttacaggctt
    21961 caaaaatctc ggtaattaat gacacaacaa ccattatcga tagcttcacc cactgctttc
    22021 caacaggttc atgcactgcc attatgggac caagcggcat tggaaaaagt acgttgctgc
    22081 gtattttagc cggtcaagaa gtaccttatt caggaaccac catgcttggc agttatgaac
    22141 tgtccacact taccgaaatg tcacgtcaca tggcgatacg ttatgttcct caagatatag
    22201 gggtacttaa aacgacagtt agacagaact tacaactaac ggcaccaaat gcctgcgata
    22261 gcgaattctt tgacgcctta gctctagccg aagtagatat taacctcgat tatgatgcca
    22321 gccttctttc tggtggccag cagcaacgcg tcgctctagc tagtatattt ctcaatcaag
    22381 ccagcatttt cttgttagat gaaccaacga gtgcacttga taaaaaaaca gccttatcca
    22441 tcatgaaaaa cctaactgaa ttcgcgcaaa aagaaaataa aaccataatc atggtaaccc
    22501 atgatgcaga gctagcccaa cgagccgact ttatattgac actacaaaaa aatgctcaat
    22561 tacaggatga agaagtatga cttatcaaaa taccccatct tccaaatcaa acattcccgc
    22621 gagcgcaaaa tatcgtttat acagggtggg agctggatgg gcgttggttg cggcactcga
    22681 agccttaacc tacacagttc ttgcactatc attggtaaaa caagccccgc cactaggtgt
    22741 catatcagca gcaattgtcg ctattttggt gacggttcta gtaacacgag cggggtttat
    22801 atctggtgcg caattagccg gagatttgta ctcggcagtc ggtcaatctc ttagtaaagc
    22861 aaaactttct tggtttaacg atcagcatcg aacgcaacta actcaacttg ccgaacgagg
    22921 cattcctggc tttatgtcaa tcccagctca ccaattacaa acatttttgc acacgccatt
    22981 agtaccctta ttcttgatcg ctggcatcgg aatcgttggg ggggcagatg ttgcactaat
    23041 cagtgcagtc tcattgatag gcgcattgct gctgcaatac aaagcacaga atcacctcag
    23101 taactctgac agcgaaagac acaacgctga tgttcaagcc acaaaatcaa cgctcgagct
    23161 catagatcac cttgatttgc ttcgctcaac ggcaggacct gaacgagcga tagaaaggat
    23221 tgaccaaagt tggtgtacac aagaaaaagt acattcgaga atcaacctaa ctgcatccat
    23281 ggccacttta acctctgcac ttgcaacggt cttccctttg gcctgcgtca ctatctacct
    23341 agttgtagaa ggggttaccc aaccactatt gattttgggg ctgctgatat taattaccag
    23401 agcggctgca ccactaggag aattagcctt agctggtttc gccatcaacg acgtaaagtc
    23461 ctcaataaga gattacaacc agctaaccaa tgtaccaact ctacctgaac ccaaaccgga
    23521 aaatgctatt agtcctaata actacaattt cgaactaaat catgttggct atttggatct
    23581 tttcaaggac gccaatgtag aaatagtaca aggtgaaaaa gttgtaatca atggcgtaag
    23641 tggtagcgga aagagcacgt tattaggatt attcttaagg tttgatgacc ctaaccaagg
    23701 tcatatttcg cttggtggca taaacctcca gaatattcca tacgacatat taatccagca
    23761 catcgcctat gtcgctcagg atccaataat atttactgga acattggccg aaaatattcg
    23821 tttaggtaac ccagaggcaa gtaatgctga agtagaactc tttgctaggc aagcgcaact
    23881 gagtgaactt attgacttat caggcgatgg aataaaccaa agtgtaggcc agaaaggatc
    23941 aaggctttct ggaggggaaa gacaaagagt cgcaattgct cgagctctaa taaaaaaagc
    24001 acctatccta attttagatg aagccacctc tgcacttgat gaagtaaccg aacagaaaat
    24061 agcacaacaa actcaagcat taggttcaac tgttattgtg gtaacacaca gagacaagaa
    24121 agtttggcat ccaacgctag aactcacgat tgataaacaa agagtcaatg ttcttcgtct
    24181 taggaccaac agtatacaag attacgaaaa atcggcggct ccgcgattaa gtagagcaat
    24241 aagttcgaga tctttttaa
//
