BGC0002476: enterobactin biosynthetic gene cluster from Escherichia coli str. K-12 substr. MG1655
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Location: 619,384 - 629,713 nt. (total: 10,330 nt).
This entry is originally from NCBI GenBank U00096.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002476
Short description enterobactin biosynthetic gene cluster from Escherichia coli str. K-12 substr. MG1655
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
U00096.3
619384 - 629713
via Heterologous expression, Enzymatic assays
Compounds
  • enterobactin
Species Escherichia coli str. K-12 substr. MG1655 [taxonomy]
References
Chemical products information
enterobactin Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • b0588
  • AAC73689.1
  • fepC
 619384 - 620199 (-) ferric enterobactin ABC transporter ATP binding subunit
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    • b0589
    • AAC73690.1
    • fepG
    		 620196 - 621188 (-) ferric enterobactin ABC transporter membrane subunit FepG
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      • b0590
      • AAC73691.1
      • fepD
      		 621185 - 622189 (-) ferric enterobactin ABC transporter membrane subunit FebD
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        • b0591
        • AAC73692.1
        • entS
        		 622300 - 623550 (+) enterobactin exporter EntS
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          • b0592
          • AAC73693.1
          • fepB
          		 623554 - 624510 (-) ferric enterobactin ABC transporter periplasmic binding protein
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            • b0593
            • AAC73694.1
            • entC
            		 624885 - 626060 (+) isochorismate synthase EntC
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              • b0594
              • AAC73695.1
              • entE
              		 626070 - 627680 (+) 2,3-dihydroxybenzoate-AMP ligase
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                • b0595
                • AAC73696.1
                • entB
                		 627694 - 628551 (+) enterobactin synthase component B
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                  • b0596
                  • AAC73697.1
                  • entA
                  		 628551 - 629297 (+) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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                    • b0597
                    • AAC73698.1
                    • entH
                    		 629300 - 629713 (+) proofreading thioesterase in enterobactin biosynthesis
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                      Biosynthesis information
                      Annotation changelog

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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