LOCUS       BGC0002477             23956 bp    DNA     linear   BCT 15-DEC-2016
DEFINITION  Streptomyces sp. CB00072 scaffold1, whole genome shotgun sequence.
ACCESSION   BGC0002477
VERSION     BGC0002477
KEYWORDS    .
SOURCE      Streptomyces sp. CB00072
  ORGANISM  Streptomyces sp. CB00072
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:47:46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1870362
            Orig. end    :: 1894318
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..675
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.4; E-value: 6.2e-55)"
                     /gene_kind="regulatory"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007450396.1"
                     /locus_tag="AMK17_08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="OKI59850.1"
                     /transl_table=11
                     /translation="MPAGSWRILVVDSDERSARDLTRSLQRHRHDARAVTTGAAALREH
                     TDADVVLLDLDLPDIDGLEICRSIATTSDIPVLAVTAHGSELGCVLGLQAGADDYVVKP
                     YGFRELLARVDAVMRRARPKPEAPMVMQVGPLFIERTTRTVVLHGRVIPLTRKEFDLLQ
                     LLASPPGEVVPRRSILQRVWQDTDMARSRTIDTHITSLRRKLGSPDWILTVRGVGFRLM
                     QR"
     subregion       1..23956
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23956
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..675
                     /locus_tag="AMK17_08255"
     gene            complement(737..1657)
                     /locus_tag="AMK17_08260"
     CDS             complement(737..1657)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007450398.1"
                     /locus_tag="AMK17_08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase"
                     /protein_id="OKI59851.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-13, bitscore:
                     42.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPSPCLPPAAPADGLSDPVRAIELDAGGVTLSGLLALPDVSLP
                     RATVVALHGGGMRAGYFHGRADPATSLLSLAASCGYAALALDRPGYGSSAAGAPEGAGL
                     EEQGARIRQALSGFARRRPPGAGFFLVGHSLGGKVALSTAAGWSGDGLLGVDVSGISDR
                     WAVDPGILTAADGKRTRGLHWGPLSLYPPHTFRLAQRLVAPVPGREAAEMADWPRVYPR
                     VARSVHVPVRFTFAEHERWWRCDAETVAAMTAKLASPLVRAERLAGAGHNISLGRAARS
                     YHLRVLAFLEECLAGAGQLRDGSDR"
     gene            complement(1701..2492)
                     /locus_tag="AMK17_08265"
     CDS             complement(1701..2492)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007450401.1"
                     /locus_tag="AMK17_08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxidoreductase"
                     /protein_id="OKI60412.1"
                     /transl_table=11
                     /translation="MGRGIALTCLRRGDTVVIIGRDRKKGESFLAAADGIGAGARAHFI
                     PADLSLISENERVVRQITEELPAVDALVLCARHFLARRRETVEGHEGTLALFYLSRFLL
                     SHGLRDLLAKAPRPVIMNVAGPGSPTGEIHWQDLQMKRDYDGVAAQMQGGKANDLLGVA
                     FADRYGATDRTRYVLFNPGGVSTSFSGEYDAATRRHVEMLKRTAKSVEAGIAPIIRCLD
                     DPPAEPVSAFVEWQRMSLADTSFDVHDARRLDEKTRELLSR"
     gene            complement(3134..4612)
                     /locus_tag="AMK17_08270"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(4738..5421)
                     /locus_tag="AMK17_08275"
     CDS             complement(4738..5421)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018103031.1"
                     /locus_tag="AMK17_08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="OKI59852.1"
                     /transl_table=11
                     /translation="MSQRSDALPLIDRDDVDAVLVEVISVEGPERQSAVADAIAAHWRS
                     AEWPAELVSVSCYTSTDGNSVLTYAQWLSRAALRESLRREGGVSRGEPDWGVAGARSQG
                     AVPFQLYRVVRGGALTDPAPVPECFPAAVFPMAGVEAGRQWIDGLLAAEERAEGEERAY
                     PGAIAANFHVGLDDGSVLVLSEWASEKEAAEHIDEVIQPLLEAAGGGDAGARYIHRLTF
                     AGAAG"
     gene            complement(5566..6249)
                     /locus_tag="AMK17_08280"
     CDS             complement(5566..6249)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007450404.1"
                     /locus_tag="AMK17_08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="OKI59853.1"
                     /transl_table=11
                     /translation="MTELISLDAPDLRRTDVASVFVGQRYARSREEALTVLEQTVVEWS
                     GAPWPAGILSFSCFLSAEEDTVLTYAQCADGDSYRPFVRSLRGPAVAGAVEYRPRRSVV
                     VRGASGVPGCVITATFDVDGAERQDRVVNSLVDVLDVPPAEQPPGMLSANFHTSVDATR
                     VLNYAEWTSVEAHLAFLDSTTRVKTLRASGDVPGVRPIGFKRFHLYRSIAPGESRASIN
                     PVRIS"
     gene            complement(6278..7507)
                     /locus_tag="AMK17_08285"
     CDS             complement(6278..7507)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 124; E-value:
                     8.7e-38)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018103039.1"
                     /locus_tag="AMK17_08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arabinose transporter permease"
                     /protein_id="OKI59854.1"
                     /transl_table=11
                     /translation="MTANGTTDARGAASDAAPWGARQWALLCVLSGNMLLDAVEVSVVL
                     VALPTIGEAMDMPLLAVQSLMSGFALGFAALLLLGNRIAALCGRRRAYLGAMALFALAS
                     VIGGTTDSEAVLVATRVVKGCCAALTAPTGLAIISTAFRDGPQQRKAVSVYSMFGATGF
                     TAGLLLSAALLESSWRWTLLFPAPLALVLLVFATRIVPHETGAGGRTPRLKPALLRNGR
                     LLRSAVGAASLNGTYAGLLLLITFQLQQRLGWSPWQSALGLLPACVPLMVTVPFAGRLV
                     ARWGADRLIALGALAPFLGCAYFLWSAPTGSYGAAVLPALVLVEAGFVLSFAALNMQAT
                     AGVRAAERGSAVPLYQTGVQLGGVVTLPLVALLLTTYQGERPALALITFISAVGLLAAL
                     TGPRTSEERE"
     gene            complement(7619..7861)
                     /locus_tag="AMK17_08290"
     CDS             complement(7619..7861)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018961662.1"
                     /locus_tag="AMK17_08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="OKI59855.1"
                     /transl_table=11
                     /translation="MTAEPVNGGAAPPRLLRVEKGSPSDEELAALTAVLLARAGAVPDS
                     GPDGGRASAGPEARWRRPEREAAYANPRAWRRDSG"
     gene            complement(7858..9390)
                     /locus_tag="AMK17_08295"
     CDS             complement(7858..9390)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 712.6; E-value: 5.3e-216)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453034.1"
                     /locus_tag="AMK17_08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylmalonyl-CoA carboxyltransferase"
                     /protein_id="OKI60413.1"
                     /transl_table=11
                     /translation="MGELGERKRLAEQGPDPRATERQHAKGKLTARERIALLLDKGSFT
                     EVEPLRRHRASGFGLEAKRPYTDGVVTGWGTVEGRTVFVYAHDFRIFGGALGEAHAQKI
                     HKIMDLAVAAGAPLVSLNDGAGARIQEGVSALAGYGGIFSRNTRASGVIPQISVMLGPC
                     AGGAAYSPALTDFVFAVRGISQMFITGPDVVQAVTGEEISQDGLGGADVHAGVSGVAHF
                     VYDDEETCLAEVRFLLCLLPANNRELPPVVPGVDRADRLCDALPGLVPDEAGRSYDIRA
                     VIEELVDEGEHMEVHAVWAPNLVCSLARLDGQVVGIVANQPAAMAGVLDITASEKGARF
                     VQFCDAFNIPLVTLVDVPGFLPGVRQEHEGIIRRGAKLLYAYCNATVPRISVVLRKAYG
                     GAYIVMDSRSIGADIALAWPGNEIAVMGAEGAANVVFRREIAAAEDPEETRRQKIEEYK
                     RELVHPFYAAERGLVDDVIDPRETRSVLIRSLSMLRTKDSGLPRRKHGNPPQ"
     gene            complement(9441..10205)
                     /locus_tag="AMK17_08300"
     CDS             complement(9441..10205)
                     /NRPS_PKS="Domain: PKS_KR (8-151). E-value: 1e-09. Score:
                     30.4. Matches aSDomain:
                     nrpspksdomains_AMK17_08300_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     185.5; E-value: 2e-56)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453033.1"
                     /locus_tag="AMK17_08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dehydrogenase"
                     /protein_id="OKI59856.1"
                     /transl_table=11
                     /translation="MTSDSPRITLVTGANKGIGRAVVRRLGELGQRVYLGARDVERGRN
                     AERELRAEGLDVRFVQLDVTDESSVALAAKRIEEETGHLDALVNNAGTGAPVRAPSRTP
                     ASVVRRTYETNVFGVITVINAMLPLLRRSRAARIVNVSSVVGSLTHAAALDDPTGEFPK
                     GTYPAVLDYGTSKAALNAVTITYANELRPERILVNAVSPGFCSTDINGHQGHLTPEQGA
                     RIPVLLATLGDDGPTAVFLGEDGSPTGQRLAW"
     aSDomain        complement(9753..10181)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08300_PKS_KR.1"
                     /evalue="1.00E-09"
                     /label="AMK17_08300_PKS_KR.1"
                     /locus_tag="AMK17_08300"
                     /protein_end="151"
                     /protein_start="8"
                     /score="30.4"
                     /tool="antismash"
                     /translation="TLVTGANKGIGRAVVRRLGELGQRVYLGARDVERGRNAERELRAE
                     GLDVRFVQLDVTDESSVALAAKRIEEETGHLDALVNNAGTGAPVRAPSRTPASVVRRTY
                     ETNVFGVITVINAMLPLLRRSRAARIVNVSSVVGSLTHA"
     CDS_motif       complement(10110..10178)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK17_08300_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK17_08300"
                     /protein_end="32"
                     /protein_start="9"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGANKGIGRAVVRRLGELGQR"
     gene            complement(10243..12213)
                     /locus_tag="AMK17_08305"
     CDS             complement(10243..12213)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 417.4; E-value:
                     1.5e-126)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453032.1"
                     /locus_tag="AMK17_08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monooxygenase"
                     /protein_id="OKI59857.1"
                     /transl_table=11
                     /translation="MGGSADADVLVVGAGPVGLLLAGEVSAGGARTVVLEQLSGPTAES
                     RASILHTRTMEILAERGILDRLGDLPAGGRGHFGGIPFDLAEADPGHPYAGQWECLQSR
                     LEPVLEAWAVERGAEVRRGHVVTGLTQHDDRVEVVAFGPGGRSHRLTAAHVVGCDGEQS
                     TVRRLAGFAMTGDDATREMLRADVLGIDIPDRRLRRYADGTATAHRRGDGTTRLMVHDR
                     TRAPGPRTREPEFAEVAAAWARVTGEDISGGTAVWLNSFDDTRRQARDYRRGRVLLAGD
                     AAHVQMPVGGQALNLGLQDAAGLGRRLAARITGGKGDGGLDEYHTERHAAGTRTLTNIQ
                     AQALLLFGGPEVDGIREVCGELLGMDVVRRHLARTISGLDRPAPPPAADTTPPLSAHGS
                     PTMDRLTGKTALVTGSSRGIGRATAVRLAREGALVAVHYATNDEAARETVALIEKEGGR
                     AFPVRAELGVPGDVHELFFGLEQGLKERTGETALDIVVNNAAVTGSDGISPEDVTPEQL
                     DRYFAVNARAPYLVIQRALRNMPDGGRVINISTALTRTAVPEQVAYAMTKGAIEQISLH
                     LAKHLAPRGITVNSVAPGITDNGGPVFDIPEAVEQMAQVSAFKRVGDAGDVADVVTFLA
                     TDEARWITGSFIDASGGTLLG"
     gene            complement(12217..13161)
                     /locus_tag="AMK17_08310"
     CDS             complement(12217..13161)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-148). E-value:
                     5.9e-17. Score: 54.2. Matches aSDomain:
                     nrpspksdomains_AMK17_08310_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (157-311). E-value:
                     5.2e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_AMK17_08310_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 457.1; E-value:
                     5e-139)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453031.1"
                     /locus_tag="AMK17_08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclase"
                     /protein_id="OKI59858.1"
                     /transl_table=11
                     /translation="MTEQAPREVEHEITVSAPAPEVYRLLAEVENWPRIFPPSVYVDYV
                     EKNGDEERIRIWATANGEAKNWTSRRRLDPAGLRITFGQEVSAPPVAEMSGTWIIEPQG
                     AGCRLRLLHSYRAIDDDPAGLAWIDRAVDRNSRSELAALKTNVELAAHSAELTLTFEDS
                     VRINGSAKDAYDFVNEARLWTDRLPHVSRVSLTEDEPGVQTLRMDTVAKDGSTHTTESV
                     RVCFPHHGIVYKQTTLPALMTLHTGSWRFDEGSDGVTTATSRHTVVINTENIMRILGPD
                     AGIPQARTFLREALGANSRATLGHAKSYAEARR"
     aSDomain        complement(12229..12690)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08310_Polyketide_cyc2.2"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.20E-10"
                     /label="AMK17_08310_Polyketide_cyc2.2"
                     /locus_tag="AMK17_08310"
                     /protein_end="311"
                     /protein_start="157"
                     /score="31.7"
                     /tool="antismash"
                     /translation="LTFEDSVRINGSAKDAYDFVNEARLWTDRLPHVSRVSLTEDEPGV
                     QTLRMDTVAKDGSTHTTESVRVCFPHHGIVYKQTTLPALMTLHTGSWRFDEGSDGVTTA
                     TSRHTVVINTENIMRILGPDAGIPQARTFLREALGANSRATLGHAKSYAE"
     aSModule        complement(12229..13140)
                     /domains="nrpspksdomains_AMK17_08310_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_AMK17_08310_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="AMK17_08310"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(12718..13140)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08310_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.90E-17"
                     /label="AMK17_08310_Polyketide_cyc2.1"
                     /locus_tag="AMK17_08310"
                     /protein_end="148"
                     /protein_start="7"
                     /score="54.2"
                     /tool="antismash"
                     /translation="EVEHEITVSAPAPEVYRLLAEVENWPRIFPPSVYVDYVEKNGDEE
                     RIRIWATANGEAKNWTSRRRLDPAGLRITFGQEVSAPPVAEMSGTWIIEPQGAGCRLRL
                     LHSYRAIDDDPAGLAWIDRAVDRNSRSELAALKTNVE"
     gene            complement(13224..14009)
                     /locus_tag="AMK17_08315"
     CDS             complement(13224..14009)
                     /NRPS_PKS="Domain: PKS_KR (7-165). E-value: 2.7e-11. Score:
                     35.6. Matches aSDomain:
                     nrpspksdomains_AMK17_08315_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     252.7; E-value: 6.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453030.1"
                     /locus_tag="AMK17_08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketoacyl reductase"
                     /protein_id="OKI59859.1"
                     /sec_met_domain="adh_short (E-value: 6.1e-38, bitscore:
                     121.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQDVVKVALVTGATSGIGLATTRLLAGQGHKVFLCARTEDDVSR
                     TVKELRGEGLEVDGRAADVCSKDDIRDLVRAAVGRFGPIDILVNNAGRSGGGVTADIAD
                     ELWFDVINTNLNSVFLVTREVLTTGGMRDRPGGRVINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRQGYAAAYEVDEEQILEKFTAKIP
                     LGRYSTAEEVAGLVGYLTSDTAASITAQALNVCGGLGNF"
     aSDomain        complement(13515..13988)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08315_PKS_KR.1"
                     /evalue="2.70E-11"
                     /label="AMK17_08315_PKS_KR.1"
                     /locus_tag="AMK17_08315"
                     /protein_end="165"
                     /protein_start="7"
                     /score="35.6"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLATTRLLAGQGHKVFLCARTEDDVSRTVKELRG
                     EGLEVDGRAADVCSKDDIRDLVRAAVGRFGPIDILVNNAGRSGGGVTADIADELWFDVI
                     NTNLNSVFLVTREVLTTGGMRDRPGGRVINIASTAGKQGVVLGAPYSASKHGVV"
     CDS_motif       complement(13914..13982)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK17_08315_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK17_08315"
                     /protein_end="32"
                     /protein_start="9"
                     /score="17.8"
                     /tool="antismash"
                     /translation="LVTGATSGIGLATTRLLAGQGHK"
     gene            complement(14045..14314)
                     /locus_tag="AMK17_08320"
     CDS             complement(14045..14314)
                     /NRPS_PKS="Domain: ACP (13-83). E-value: 1.3e-17. Score:
                     55.7. Matches aSDomain: nrpspksdomains_AMK17_08320_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 119.6; E-value:
                     7.5e-37)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453028.1"
                     /locus_tag="AMK17_08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="actinorhodin polyketide synthase"
                     /protein_id="OKI59860.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore:
                     38.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATPFTIDDLKSILREGAGADEGVDLDGDILDAEFDALGYESLA
                     MLETAGRIEREYGISLDEEIFADARTPRALIALVNGQLPSAQAV"
     aSDomain        complement(14066..14275)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08320_ACP.1"
                     /evalue="1.30E-17"
                     /label="AMK17_08320_ACP.1"
                     /locus_tag="AMK17_08320"
                     /protein_end="83"
                     /protein_start="13"
                     /score="55.7"
                     /tool="antismash"
                     /translation="ILREGAGADEGVDLDGDILDAEFDALGYESLAMLETAGRIEREYG
                     ISLDEEIFADARTPRALIALVNGQL"
     gene            complement(14372..15592)
                     /locus_tag="AMK17_08325"
     CDS             complement(14372..15592)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-402). E-value:
                     1.1e-26. Score: 85.6. Matches aSDomain:
                     nrpspksdomains_AMK17_08325_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 665.9; E-value:
                     2.9e-202)"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453027.1"
                     /locus_tag="AMK17_08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl synthase"
                     /protein_id="OKI59861.1"
                     /sec_met_domain="t2clf (E-value: 9.5e-211, bitscore: 690.0,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATTVVTGLGVAAPNGLGLESYWSAVLAGRGAIGRVGRFDPTSY
                     PAQLAGEIAGFAAEDHLPSRLLPQTDRMTRLALVSADWALEDAGVVPDTLPAYDMGVIT
                     ASHSGGFEFGQKELRALWSKGGRYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQ
                     AGGLDALAQARRQIRKGTPLIVSGAIDASICPWGWVAQLASGRLSRATDPGRAYVPFDD
                     GAAGHVPGEGGALLILEDADHARARGARQVYAEIAGHASTFDPAPGGDRGPGLRRAVEQ
                     ALCDGETAPGDVDVVFADAAAVPELDRVEAEAISKVFGPRAVPVTAPKTMTGRLYSGAA
                     PLDVATACLSIRDGVIPPTTNTSLSPHYDIDLVTGPPRETPVRTALVIARGYGGFNSAV
                     VVRAPRD"
     aSDomain        complement(14387..15391)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08325_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-26"
                     /label="AMK17_08325_PKS_KS.1"
                     /locus_tag="AMK17_08325"
                     /protein_end="402"
                     /protein_start="67"
                     /score="85.6"
                     /tool="antismash"
                     /translation="PQTDRMTRLALVSADWALEDAGVVPDTLPAYDMGVITASHSGGFE
                     FGQKELRALWSKGGRYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQAGGLDALA
                     QARRQIRKGTPLIVSGAIDASICPWGWVAQLASGRLSRATDPGRAYVPFDDGAAGHVPG
                     EGGALLILEDADHARARGARQVYAEIAGHASTFDPAPGGDRGPGLRRAVEQALCDGETA
                     PGDVDVVFADAAAVPELDRVEAEAISKVFGPRAVPVTAPKTMTGRLYSGAAPLDVATAC
                     LSIRDGVIPPTTNTSLSPHYDIDLVTGPPRETPVRTALVIARGYGGFNSAVVVR"
     gene            complement(15589..16869)
                     /locus_tag="AMK17_08330"
     CDS             complement(15589..16869)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-401). E-value:
                     3.6e-59. Score: 192.6. Matches aSDomain:
                     nrpspksdomains_AMK17_08330_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 493.8; E-value:
                     7.2e-150)"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453026.1"
                     /locus_tag="AMK17_08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ACP synthase"
                     /protein_id="OKI59862.1"
                     /sec_met_domain="t2ks (E-value: 8.7e-245, bitscore: 802.7,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVYGRQVVITGIGVTAPGGPGTKGFWQLLTDGRTATRRISFFD
                     PSPFRSQVAAEVDFDAEACGLGPQEIRRMDRAAQLAVVTAREAAADSGLAFHTLDPGRM
                     GVTIGSAVGATMGLDEEYRTVSDGGRRELVDHEYAVPHLYNYMVPSSFAAEVAHAMGAE
                     GPASVVSTGCTSGLDAVGYATEVIREGTADVMIAGATEAPISPITVACFDAIKATTPRN
                     DDPAHASRPFDASRNGFVLGEGAAVFVLEDGESARRRGAHVYAEVAGYATRSNAFHMTG
                     LRPDGKEMAEAIRIAMAEARVNPEDIDYINAHGSGTKQNDRHETAAFKLSLGEAAYRTP
                     VSSIKSMVGHSLGAVGSIELAASALAMEHHVIPPTANLRTPDPECDLDYTPLTARERRT
                     DTVLSVGSGFGGFQSAVVLARPDRRRR"
     aSDomain        complement(15667..16845)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08330_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.60E-59"
                     /label="AMK17_08330_PKS_KS.1"
                     /locus_tag="AMK17_08330"
                     /protein_end="401"
                     /protein_start="8"
                     /score="192.6"
                     /tool="antismash"
                     /translation="VVITGIGVTAPGGPGTKGFWQLLTDGRTATRRISFFDPSPFRSQV
                     AAEVDFDAEACGLGPQEIRRMDRAAQLAVVTAREAAADSGLAFHTLDPGRMGVTIGSAV
                     GATMGLDEEYRTVSDGGRRELVDHEYAVPHLYNYMVPSSFAAEVAHAMGAEGPASVVST
                     GCTSGLDAVGYATEVIREGTADVMIAGATEAPISPITVACFDAIKATTPRNDDPAHASR
                     PFDASRNGFVLGEGAAVFVLEDGESARRRGAHVYAEVAGYATRSNAFHMTGLRPDGKEM
                     AEAIRIAMAEARVNPEDIDYINAHGSGTKQNDRHETAAFKLSLGEAAYRTPVSSIKSMV
                     GHSLGAVGSIELAASALAMEHHVIPPTANLRTPDPECDLDYTPLTARERRTDT"
     CDS_motif       complement(16138..16176)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK17_08330_0002"
                     /evalue="2.70E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="AMK17_08330"
                     /protein_end="244"
                     /protein_start="231"
                     /score="8.1"
                     /tool="antismash"
                     /translation="FDASRNGFVLGEG"
     CDS_motif       complement(16660..16695)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK17_08330_0001"
                     /evalue="7.00E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="AMK17_08330"
                     /protein_end="70"
                     /protein_start="58"
                     /score="1.0"
                     /tool="antismash"
                     /translation="FDAEACGLGPQE"
     gene            complement(16866..17192)
                     /locus_tag="AMK17_08335"
     CDS             complement(16866..17192)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 153.3;
                     E-value: 3.3e-47)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453025.1"
                     /locus_tag="AMK17_08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyketide synthase"
                     /protein_id="OKI59863.1"
                     /transl_table=11
                     /translation="MYSTLIVARMEPGSAGEVARHFSAFDGTEMPELMGTRRRELFSFR
                     GLYFHLQDFDGENGGERIEQTKGDPRFVGISQDLKPFIEAYDPATWRSPADAMARRFYH
                     WSAE"
     gene            complement(17233..18735)
                     /locus_tag="AMK17_08340"
     CDS             complement(17233..18735)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 539; E-value:
                     2.1e-163)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453024.1"
                     /locus_tag="AMK17_08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monooxygenase"
                     /protein_id="OKI59864.1"
                     /transl_table=11
                     /translation="MDASVMVVGAGPAGLMLAGELRLAGIDVVVLDRLPQRTGESRGIG
                     LTPRTVEVLDQRGLLPRFGDIEMSGLGHFGGIPLDFGVLGGGDRAARTVPQSATESVLE
                     SWARELGADIRRDHEFTGLTDHGGHVEAQVRGPAGEQVLNCRFLVGCDGGRSAVRKAAG
                     FDFPGTPATTELLLADIRGVDLEPRMVADRVTDGMVMTARLGDGVHRVIVAERGAPPQR
                     RTGPPAFAEVADAWKRLTGIDISHAEPVWLSAFGDATRQVTEYRRGRVLLAGDSAHIHL
                     PAGGQGMNTSVQDSVNLGWKLAAVLHGAAGPALLDTYHSERHEVGRRLLANTRAQSLLI
                     LGSEEVQPLRDILTELARYEEVARHFAAKAGGLDIRYDVGSGPNPLLGMRMPRLELLRG
                     TTVTSSTELLRAGRGVLLDLADTPRLRRRAAPWADRVDLVTAAPRGTAALGGGLDGTSA
                     VLLRPDGHVAWIAPGSHHDLPMALERWFGPARQHGTAHTRAV"
     gene            complement(18816..19799)
                     /locus_tag="AMK17_08345"
     CDS             complement(18816..19799)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 233.7; E-value:
                     5.5e-71)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453021.1"
                     /locus_tag="AMK17_08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase"
                     /protein_id="OKI59865.1"
                     /transl_table=11
                     /translation="MGPLTGFWQTKILLTAVESGLFTELSGSSATAEELSTRLGYRMPG
                     ASDFFLALAGMGLLDASEAGEFRNSPAADRYLVRARPEFIGGYLQFCERELNPAWEGLG
                     TALRTGAPQNPAAVEGNPYETLYQDPESTESFLESMDTLNTPLLRRLGEIDWSGYDSFV
                     DVGGARGNVAHHLALSNPHLKGAVFDLPQLEGAFTTHMAALGDDGAVSFHGGDFFAGPL
                     PESDVLIFGHVLHNWGVDERRTLLRKAHDAIRPGGAVIIYDPMVSNSAPPLYATLAALS
                     MLVWSAGGGEYPVSDCHAWLEEAGFRPETVGPEDTPDDVLVIGRKS"
     gene            complement(20142..21608)
                     /locus_tag="AMK17_08350"
     CDS             complement(20142..21608)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 330.6; E-value:
                     2e-100)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453020.1"
                     /locus_tag="AMK17_08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EmrB/QacA family drug resistance transporter"
                     /protein_id="OKI59866.1"
                     /transl_table=11
                     /translation="MSQVRDDRLDPGLLRLIGVTLLGGIMGILDSTMVTVAADTLAAEF
                     NTSLSSISWATTGYLLALTVTIPITSWAVGRFGVRKLWLFGLVLFLVGSLASALAWNVE
                     SLVAFRVVQGVGAGVVDPLVLVILARAAGPSRAGRVMGMMGVVLSLGPVLGPVLGGVVL
                     ESMGWRWMFYINLPIGIVAVLLALRVIPVGAPLKRGSGPRLDIIGALLMAPGLAAILLA
                     LTEAGERARFAVPSVLIPLALGVALLVGYVIHALRARRTEPLIDIRLFSSRSFAASVTV
                     QGLVGLATFAVLFALPLYYQVLHGHGARAAGLLVAPLGLGSALAMPIAGRLSDRLGARN
                     LVRGGAVVAALASVGLTRIGADSGEVWSVLAAFAVGLGLGGVGAPTMGSLYRTLPPEKV
                     PQGSSVVYNLNQLGGALGVACVALILAAVGNGAAAGGAGIGGFHGAYWFVFAVTLVILA
                     ASPLLPGRPEAPTAVQAEASSADGSAMAHP"
     gene            21731..22426
                     /locus_tag="AMK17_08355"
     CDS             21731..22426
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 107.8; E-value: 1.5e-32)"
                     /gene_kind="regulatory"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453018.1"
                     /locus_tag="AMK17_08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="OKI59867.1"
                     /transl_table=11
                     /translation="MGLTRYDGGVNGAKTSSASRREAPRGRIDKRQAILEAAFRTFARE
                     GYGQSCVREIAAEAGVAKPTIYNHLGDKETLFREAMLAAVGRTSGAGLGALEQLREPDG
                     DVRPMLEEAGLRILKNHCDPESQALRWLLNAEAARFPDLLETIQREGAQRLHDALADRL
                     ARFALSGRLHTSDPDLAAEQFLALLTGPMALRTRLGTRKVSDAELRAVGRAAVDTFLRA
                     YAPRTVDTP"
     gene            22543..23250
                     /locus_tag="AMK17_08360"
     CDS             22543..23250
                     /NRPS_PKS="Domain: PKS_KR (2-133). E-value: 7.1e-09. Score:
                     27.7. Matches aSDomain:
                     nrpspksdomains_AMK17_08360_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     176.4; E-value: 1.2e-53)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_007453017.1"
                     /locus_tag="AMK17_08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="short-chain dehydrogenase"
                     /protein_id="OKI59868.1"
                     /transl_table=11
                     /translation="MTTTLITGANKGLGYETARRLTEAGHTVLLGARDPRRGRAAAERI
                     GARFLPLDVTGEESVLAASDRVREEFGHLDVLVNNAGITGPRKEAAELTADDIKKLYDT
                     NVFGAVRVTRAFLPLLRAGESPTVVNVSSGLGSLAIAADPERFESLLPVYYPSLGYNSS
                     KAALNMITVQYAKAFPEITFNAVDPGWTATDLNDHRGVQTVEEGAAVIVRMATLGGDGP
                     TGGFFGNTGPVPW"
     aSDomain        22549..22941
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK17_08360_PKS_KR.1"
                     /evalue="7.10E-09"
                     /label="AMK17_08360_PKS_KR.1"
                     /locus_tag="AMK17_08360"
                     /protein_end="133"
                     /protein_start="2"
                     /score="27.7"
                     /tool="antismash"
                     /translation="TTLITGANKGLGYETARRLTEAGHTVLLGARDPRRGRAAAERIGA
                     RFLPLDVTGEESVLAASDRVREEFGHLDVLVNNAGITGPRKEAAELTADDIKKLYDTNV
                     FGAVRVTRAFLPLLRAGESPTVVNVSS"
     CDS_motif       22555..22626
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK17_08360_0001"
                     /evalue="1.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK17_08360"
                     /protein_end="28"
                     /protein_start="4"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LITGANKGLGYETARRLTEAGHTV"
     gene            complement(23363..23626)
                     /locus_tag="AMK17_08365"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
ORIGIN
        1 gtgccggccg gctcctggcg catcctcgtg gtcgacagcg acgaacggtc cgcgcgggat
       61 ctgacccgca gtcttcagcg ccaccggcac gacgcccgcg cggtcaccac cggagcggcc
      121 gccctccgtg aacacaccga cgccgatgtg gtgctcctcg acctcgatct cccggacatc
      181 gacgggctgg agatctgccg gtccatcgcc acgacgagcg acatccccgt cctcgcggtc
      241 accgcgcacg gcagcgaact cggctgtgta ctgggattac aggcgggcgc ggacgactac
      301 gtggtcaagc cgtacggctt ccgtgagctg ctggctcgag tcgacgccgt gatgcgccgg
      361 gcccggccga agcccgaggc tcccatggtc atgcaggtgg gcccgctgtt catcgagcgg
      421 accacgcgca cggtggtgct gcacggccgc gtcattcccc tcacccgcaa ggagttcgac
      481 ctgctgcaac tcctcgcgtc ccctcccggc gaggtcgttc cccggcggag catcctccag
      541 cgcgtctggc aggacaccga tatggcgcgc agtcgcacga tcgacacaca catcaccagc
      601 ctgcgcagaa agctcggttc gccggactgg atactcaccg tccggggtgt cggcttccga
      661 ctgatgcaga ggtgaacagc gccccggaac cggcggcggt gcgccgacgc cgtgccgatg
      721 acgtgcgtcc tggccctcag cggtcactcc cgtcccgtag ctgtcccgct cccgccagac
      781 actcttcgag gaaggccagg acccgcaggt ggtagctccg ggccgcccgc cccaggctga
      841 tgttgtgccc ggcgcccgcc agacgttcgg cacgtacgag aggcgacgcc agcttcgccg
      901 tcatggccgc caccgtctcc gcgtcgcacc gccaccatcg ttcgtgttcc gcgaaggtga
      961 agcgcaccgg aacgtgcacg gagcgtgcca ctcgcggata gacccgcggc cagtccgcca
     1021 tctccgccgc ctccctgccg ggtacgggcg cgacgagccg ctgcgccagc cggaaggtgt
     1081 ggggcggata cagggacagc gggccccagt gcaggccgcg ggtgcgcttg ccgtcggccg
     1141 cggtgagaat cccgggatcg acggcccagc ggtcgctgat gccggagacg tccaccccca
     1201 gcagcccgtc accgctccag cccgccgccg tcgacagcgc gaccttcccg cccagtgagt
     1261 ggccgaccag gaagaacccc gcacccgggg gacggcgccg cgcgaaaccg gacagcgcct
     1321 gccgtatccg ggccccttgc tcttcgagcc cggcgccttc aggggccccc gccgccgaac
     1381 tcccgtatcc gggccggtcc agcgcgagcg ccgcgtaccc gcaggacgcc gcgagcgaga
     1441 ggagcgaggt ggctggatcg gcgcggccgt ggaagtaccc cgcgcgcatg ccgccgccat
     1501 gcagcgcgac caccgtggcg cgtggcaggg agacgtcggg aagggccagc agtccggaaa
     1561 gagtgacacc acccgcgtcc aactcgatcg cgcggacagg gtcgctcaac ccgtcggccg
     1621 gagcggccgg ggggaggcac ggggagggct ggggcatggg gactccacat cggtaggcgc
     1681 ctggcgcggc tccgtcgtcg tcaccgggag agcagttccc gggtcttctc gtcgagccgc
     1741 cgggcgtcgt gcacatcgaa ggaggtgtcc gccaggctca tccgctgcca ttccacgaac
     1801 gcgctcaccg gctcggcggg cgggtcgtcc agacacctga tgatcggtgc gatgcccgcc
     1861 tccaccgact tggccgtcct cttcagcatc tcgacatggc gccgggtcgc cgcgtcgtac
     1921 tcaccggaga agctggtgga gacgccgccg gggttgaaca gcacatagcg cgtgcgatcg
     1981 gtggcaccgt accggtccgc gaaggcgaca ccgagcaggt cgttggcctt gcctccctgc
     2041 atctgcgccg cgactccgtc gtagtcccgc ttcatctgga ggtcctgcca atggatctcg
     2101 cccgtcggcg aaccgggtcc cgccacattc atgatgaccg gccgcggggc cttcgccagc
     2161 agatcgcgca gcccgtggct gagcaggaac cggctcaagt agaagagcgc gagggtgcct
     2221 tcgtgcccct ccaccgtctc ccgccgccgc gcgaggaagt gccgtgcaca cagcacgagg
     2281 gcgtccacgg cgggaagctc ctcggtgatc tgccggacaa ccctctcgtt ctcactgatc
     2341 agactcagat cggcggggat gaagtgagcc ctggctcccg cgccgatgcc gtcggcggcg
     2401 gccaggaagg attccccctt cttccggtcg cgtccgatga tgacgacggt gtcgccccgc
     2461 cgcagacagg tgagcgcgat ccctcgcccc atcccgtcgg taccgccctg aaccacgatg
     2521 tgcttcacca ggattctccc agtcctcttc gcgtggcgcg gcgccgcgcc ggattcgacg
     2581 tggactcaac ttagagacag cacaggcccc ttcgcaaccg cagtagatac tttcttgaac
     2641 cgcgcggttc atatttgcag tctggttggt aagctgctgc catggtggcg acgaggtccg
     2701 gagttcctca tgtgcagacc ccagcgagca cggccgagtc cggagggtta cggccgcccg
     2761 cgccgcccgc gacctcacgg ggcgacgcgc accggtccac ccgtagcggc tcggacagca
     2821 ccagccggga aagcacggga acggtgagcg ccgggccctc gcggcactcc gcgatctcca
     2881 cggagtggga cgcgacgagc gactcgacca ggcggtcgaa ctccccggcc cgccggccgg
     2941 agagctccat cgcccgcagc aggtcccgct cccgtaccgg ccggggaagc cagcacagca
     3001 gtgacagcag ctcgcgctcg gccgccggca gccgctggtg cgcggtcccg acacggcgga
     3061 gcgagtcgtg ctgaggcccc cgcagcacgg ccagccgctg gccgccgtcc cgcgcacgga
     3121 acagcaggtc gcgtacgcgc agatccggac gcgccgcgag ccgctccccc aacgcccgta
     3181 cagccagcgg cagtccgtcg tacagccgga ccaactccgc cgcctgggag cgctccccgg
     3241 cgatacgccg cgcacccgcg gcgccgccga gcagcgccac accctcgtcg tcgctcatcc
     3301 ctctcagttc cacccgggtg acggcgccgg gcaggccctc aaggcgccag cgggaggtga
     3361 cgaccaccgc gcagtccgga ctgctgggca gcagaggtat cagctgtccg ggtgagccgg
     3421 cgtcatcgag gacgaccagc atccggcgtt ccgaggtcca gctgcggaag agcctcgcca
     3481 agtcctccac ggccgagggc agttgcccgt ccggatgccc cgatgacagc aacagtgagg
     3541 tcagggcgtc ccggctggag accggagcgc cgtcgggacg gtgcagtgtc gcgaagagct
     3601 gaccgcccgg atagtggccg cgtaactggt gggacgcctc caccgccgtc accgtcttgc
     3661 cggttcccac gcctcccgtc accacgacga cacgcaccgc cggcagagca ctcgccgcct
     3721 ctcccgccgg gcggcccgcc gcgacgatcg ccgccacctg ccgggcgcgt ccggtgaagt
     3781 cgacggtgcg cggcggaagt tcggcgggga tgaccacccg gcccaccgtc tcgccggccg
     3841 gggccggccc cgtacggcgc tccggcggcg ggacgtcttc cagtacgctc cgctgaaggt
     3901 cccggacctc cgccgagggc tccagaccga gttcgccgac catcgccgcc cggagccgcc
     3961 gataggcgtc gagggccacc tcccggtggc ccgagcgcgc cgcggcacgc atgagccggc
     4021 cggccagcac ctcgttcagc gggtgggcga gcgtcagccc tttcagctcg ctgagcagtt
     4081 cgcggtggac ccccagctcc atgtcggcct cgatccgctg ctccagggcc gccatccgga
     4141 gatcttcgag cctggcctgc tcggccgaga gcagcgcacc ggtggccgtg cccgagaagg
     4201 ccggcccccg ccacagtgcg agggcctcgc ggaaggcgtc cgaggccggc cctgggcgtc
     4261 cttcgctcag tgcggcccgg ccccgggcgc agagttcctg gaagcgccac aggtccagct
     4321 gtcccgcgcc gacccggagc cggtaaccgc gtgactcggt ctgcacccac ggtccgcccc
     4381 cggcgccctc tcgcagtgcc ttgcgtacgt ggtagatgta cgtctgcacg gtcttgcgcg
     4441 cgagcttcgg gggagtgtcg tcccacagct cctccactag actctccagc ggaaccacct
     4501 ggttggcgtg gacgagcagc agggaaagca cctgacggct catgggcgag gcgggctcgc
     4561 acgggccccg gtccccgcgt acctccactg gtccgagaat ggaaaagagc atggattctc
     4621 ctctctgagt gcgcagttac cacttgtgac atcggaggtc gcggcggtgt gcaggctcgt
     4681 accgggagaa cggccagaat tttgtccacg ggtgcggccg gagacagccc ggtggactca
     4741 gccggcagcg cccgcgaagg tgaggcggtg gatgtaccgc gcgcccgcgt cgccgccgcc
     4801 ggccgcctcc agcaggggct ggatcacctc gtcgatgtgt tcggcggcct ccttctcgga
     4861 cgcccactcg gagaggacga gcacactgcc gtcgtccagc ccgacatgga agttggcggc
     4921 gatcgcgccg gggtacgccc gttcctcccc ctccgccctc tcctccgcgg ccagcaggcc
     4981 gtcgatccac tgacgcccgg cctccacgcc ggccatcggg aagaccgcgg ccgggaagca
     5041 ctccgggacc ggggccggat cggtgagggc gccccctcgg acgacgcggt agagctggaa
     5101 cggcacggca ccctgggacc gggcgccggc gacaccccag tccggctccc cgcgtgagac
     5161 gccgccctcc cgccgcaggg attcccgcag cgccgcccgg gacagccact gggcgtaggt
     5221 cagcacggag ttgccgtccg tactcgtgta gcagctgacg gacaccagct cggcaggcca
     5281 ctcggcggac cgccagtgcg cggctatcgc gtcggccacc gcgctctgcc gctcggggcc
     5341 ctccacactg atcacctcga cgagcacggc atcgacatcg tcgcggtcga tcagcggcag
     5401 ggcatcagaa cgctgagaca tgcataactc ctcgctaggg atgaggcggg gtggcgcgga
     5461 ttccatcctc ggcggcactc cggtcgtttc caacggcacg ggatgaaggg ttgggagaga
     5521 aaggacaaga ttccgcagga ctcccccggg aaagtcacat cgacgtcagg agatccgcac
     5581 cggattgatg gatgcacggg attcgcctgg ggcgatgctc cggtagaggt ggaaacgctt
     5641 gaacccgatc ggccgtactc ccgggacatc gccactggcc cgcagggtct tcacccgcgt
     5701 cgtgctgtcg aggaacgcca ggtgcgcctc gaccgatgtc cactccgcgt agttgaggac
     5761 gcgcgtggca tccacgctgg tatggaagtt cgcggagagc atgcccggcg gctgctcggc
     5821 cggcggtacg tcgagcacgt cgaccagcga gttgacgacc cggtcctgcc gctcggcgcc
     5881 gtcgacgtcg aacgtcgcgg tgatgacgca ccccggaacg ccggacgcgc cgcgcaccac
     5941 cacgctcctg cgcggtcggt attcgaccgc tcccgccacg gccggccccc gcaacgagcg
     6001 gacgaacggc cggtaggaat ccccgtcggc gcactgcgca taggtgagca ccgtgtcctc
     6061 ctccgcgctg agaaagcagc tgaacgagag aattccggcg ggccagggag caccgctcca
     6121 ttccacgacg gtctgttcca gtacggtcag cgcctcctcc cggctccgtg cataccgctg
     6181 gccgacgaaa acggacgcca cgtcggtacg ccggagatcc ggcgcgtcca gggagatcag
     6241 ctcagtcatt cccgctcctg ttcattcccg gtcctgttca ttcccgctct tcgctcgtac
     6301 gcggtccggt gagcgccgcc agcagaccca cagcgctgat gaaggtgatg agcgccaggg
     6361 ccggcctttc gccctgatac gtcgtcagca ggagggcgac cagcggcagt gtcaccacgc
     6421 ctcccagctg gacgcccgtc tggtagaggg gcacggccga gccccgctca gcggcccgga
     6481 cccccgccgt ggcctgcatg ttcagcgccg cgaaggagag tacgaacccc gcctccacca
     6541 gcaccagggc cggcaggacc gccgccccgt acgaccccgt cggcgcgctc cacaggaagt
     6601 acgcgcagcc gaggaacggc gcgagcgcgc ccagtgcgat cagccggtcg gcgccccacc
     6661 gggcgaccag acggcccgcg aagggaacgg tcaccatcaa gggcacacac gccgggagca
     6721 gacccagcgc actctgccag ggcgaccagc ccaggcgctg ctggagctga aaggtgatca
     6781 gcagcagcag gccggcatag gtgccgttga gagaggccgc gccgaccgcc gaccgcagca
     6841 gcctgccgtt cctgagcagc gccggtttca gacgcggtgt tcgtcctccg gccccggtct
     6901 cgtgcggaac gatccgcgtg gcgaagacca gcagcacgag ggcgaggggc gcgggaaaca
     6961 ggagcgtcca gcgccagctc gattccagga gcgccgcgga gagcagcaga cccgcggtga
     7021 agccggtggc gccgaacatg gagtagacgg agaccgcctt gcgctgttgc ggtccgtcgc
     7081 ggaaggccgt gctgatgatg gccagtccgg tgggggcggt cagcgcggcg cagcagccct
     7141 tgaccacccg ggtcgcgacg agcaccgcct cgctgtcggt cgtcccgccg atcaccgagg
     7201 cgagggcgaa gagggccatc gcgcccagat acgcgcggcg gcggccgcac agcgcggcga
     7261 tccggttccc caggagcagc agagccgcga acccgagggc gaagccactc atcagagact
     7321 ggaccgcgag cagcggcatg tccatggcct cgccgatcgt gggcagggcc accagcacca
     7381 cggacacctc gacggcgtcc aggagcatgt tgcccgacag gacgcacagc agggcccact
     7441 gccgggctcc ccagggcgcg gcatccgagg ccgcgccgcg ggcgtcggtc gtgccgttcg
     7501 ctgtcatgtc tcgtcatcac cgtctcggtc tcgtcgtcac cgtctcggtc tcgtcatcac
     7561 cgtgcggatc ggtcgcgggt cccgcggttc ggaggggctc gtaacgcgct gcgcgccctc
     7621 agccactgtc ccgccgccac gcccgcgggt tcgcgtacgc ggcctcccgc tcgggtctgc
     7681 gccaccgggc ctcaggaccg gcggatgccc ggccgccatc cggaccggag tccgggacgg
     7741 cgcccgcgcg cgcgagcagg accgcggtca gcgcggccag ttcctcgtcg ctggggctgc
     7801 ccttctccac ccgcagcagc cgaggcgggg cagcgccgcc gttcaccggt tccgcggtca
     7861 ctgcggcggg tttccgtgct tgcggcgcgg cagaccggag tccttcgtcc gcagcatgga
     7921 gagcgagcgg atcagcaccg agcgggtctc ccgcggatcg atgacatcgt cgaccaggcc
     7981 gcgttcggcc gcgtagaacg ggtgcaccag ctcccgcttg tactcctcga tcttttgccg
     8041 gcgcgtctcc tccgggtcct cggcggcggc gatctcccgc cggaagacca cattggcggc
     8101 gccctccgcg cccatcacgg cgatctcgtt ccccggccag gccagcgcga tgtccgcacc
     8161 gatcgagcgg gagtccatca cgatgtaggc gccgccgtag gccttgcgca ggaccaccga
     8221 gatccggggc accgtcgcgt tgcagtacgc gtacagcagc ttcgcaccgc gccggatgat
     8281 cccctcgtgc tcctgccgca cgcccgggag gaacccgggc acatcgacga gggtgacgag
     8341 ggggatgttg aaggcgtcgc agaactggac gaagcgcgcg cccttctcgg acgccgtgat
     8401 gtccagtacg ccggccatcg cggcgggctg attggcgacg atgcccacca cctggccgtc
     8461 cagccgggcc agcgagcaca cgagattggg cgcccacacg gcgtggacct ccatgtgctc
     8521 gccctcgtcc acgagttcct cgatcaccgc gcgtatgtcg taggagcggc cggcctcgtc
     8581 ggggacgagt ccgggcaacg catcgcacag ccggtccgcc cggtccacgc cgggtacgac
     8641 gggtggcagt tcgcggttgt tggcgggcag caggcagagc agaaagcgca cctccgccag
     8701 gcaggtctcc tcgtcgtcgt acacgaagtg ggccacgccc gagacaccgg cgtggacatc
     8761 cgcaccgccc aggccgtcct gcgatatctc ctcgcccgtc acggcctgca cgacatcggg
     8821 gccggtgatg aacatctgcg agatcccgcg gaccgcgaag acgaagtcgg tgagcgccgg
     8881 ggagtaggcg gcgccgcccg cacacggtcc cagcatcaca ctgatctgcg ggatgacccc
     8941 ggacgcccgg gtgttgcggc tgaagatgcc cccgtagccc gcgagggcgg agactccttc
     9001 ctggatacgg gccccggcac cgtcgttgag cgacacgagc ggggcgcccg ccgcgacggc
     9061 caggtccatg atcttgtgga tcttctgggc atgggcctcg cccagcgccc cgccgaagat
     9121 ccggaagtcg tgggcgtaga cgaagaccgt ccggccctcg accgttcccc agcccgtcac
     9181 cacaccgtcg gtgtaggggc gcttcgcctc cagcccgaag ccgctcgccc ggtgccggcg
     9241 cagcggctcg acctcggtga agctgccctt gtcgaggagg agggcgatcc gttcccgggc
     9301 ggtcagtttg cccttggcat gctgccgctc ggtggcccgg gggtccggcc cctgctcggc
     9361 gagcctcttc cgctcgccca gctcgcccag gtcgtcccgt tcggtcggtt cgctcggtcc
     9421 gtccactcgg accacggccg tcaccatgcc agccgctgac cggtcgggga gccgtcctcg
     9481 cccaggaaga cggccgtcgg gccgtcgtcg cccagagtcg ccaggagtac ggggatacgc
     9541 gccccctgct ccggcgtcag atggccctgg tggccgttga tatcggtcga acagaacccg
     9601 ggtgaaacgg cgttgaccag aatccgctcc gggcgcagct cgttggcgta ggtgatggtg
     9661 acggcgttca gcgccgcctt cgacgtgccg tagtccagca ccgccgggta cgtccccttg
     9721 gggaactccc cggtgggatc gtccagggcc gcggcatggg tcagggatcc gaccacactg
     9781 ctgacgttga cgatgcgggc ggcccgcgag cggcgcagca gcggcagcat cgcgttgatg
     9841 acggtgatga caccgaacac attggtctca taggtgcggc gcaccacact ggccggcgtc
     9901 cggctgggcg cgcgtaccgg cgcgcccgtc cccgcgttgt tgaccagggc gtccaggtgg
     9961 cccgtctcct cctcgatgcg cttggcggcg agggccaccg aggactcgtc cgtgacatcg
    10021 agctgtacga agcggacatc gagtccctcg gcacgcagct cacgctcggc gttcctgccc
    10081 cgctccacgt cccgggcgcc cagatagaca cgctggccca gctcgccgag gcgccggacg
    10141 acggcgcgtc cgattccctt gttggcgccg gtgacgagcg tgatacgggg actgtcggag
    10201 gtcatgcttc gcttcctctc tcgcggtgtg cgtaagggcc ggtcatccga ggagcgtccc
    10261 gccgctggcg tcgatgaacg aacccgtgat ccagcgcgcc tcgtcggtgg ccaggaaggt
    10321 caccacgtcg gcgacatccc cggcgtcacc cacccgcttg aacgcggaga cctgcgccat
    10381 ctgctcgacg gcctcgggga tgtcgaagac cggcccgccg ttgtccgtga tccccggcgc
    10441 cacactgttg acggtgatcc cgcgcggcgc cagatgcttc gccaggtgca gcgagatctg
    10501 ctcgatggcc cccttggtca tcgcataggc gacctgctcg ggcaccgcgg tgcgggtgag
    10561 cgcggtggag atgttgatga cgcgtccccc gtcgggcatg ttccgcagtg cccgctggat
    10621 gacgaggtac ggcgcccgtg cgttcaccgc gaagtagcgg tcgagctgct ccggggtgac
    10681 gtcctcgggg ctgatgccgt ccgagcccgt caccgcggcg ttgttcacca cgatgtcgag
    10741 tgcggtttcc ccggtccgct ccttcagccc ctgctccagg ccgaagaaga gctcgtgcac
    10801 atccccgggg acgccgagtt cggcgcggac cggaaaggcc cggccgccct ccttctcgat
    10861 cagggcgacg gtctcccgcg ccgcttcgtc gttggtggcg tagtgcacgg cgaccagggc
    10921 gccttcgcgg gccagccgta cggccgtggc gcggccgatg ccccggctgg agccggtgac
    10981 cagcgccgtc tttccagtga gcctgtccat ggtgggactc ccgtgtgctg aaaggggtgg
    11041 agtggtgtcc gccgcgggcg gtggggccgg ccggtccagg ccgctgatcg tccgggcgag
    11101 gtggcggcgg acgacgtcca tgccgaggag ctcgccgcac acctcgcgga tgccgtccac
    11161 ctcgggcccg ccgaacagca gcagcgcctg ggcctggatg ttggtcaggg tgcgggtgcc
    11221 cgcggcatgg cgctccgtgt ggtattcgtc cagaccgccg tcgcccttcc cgccggtgat
    11281 gcgggccgcc agcctccggc cgagtccggc cgcgtcctgg agcccgaggt tgagtgcctg
    11341 tccgccgacg ggcatctgga catgggcggc gtcccccgcc agaaggaccc ggcctcggcg
    11401 gtagtcccgc gcctggcgcc gggtgtcgtc gaagctgttg agccacaccg ccgtgccgcc
    11461 gctgatgtcc tcgcccgtca cccgggccca cgccgcggcg acctcggcga actcgggctc
    11521 gcgggtacga ggcccgggtg cacgggtgcg gtcgtgcacc atgagacggg tggtcccgtc
    11581 gccgcgccgg tgggcggtgg cggtgccgtc cgcgtaccgt ctgaggcgcc ggtccgggat
    11641 gtcgatgccc agtacgtcgg cccggagcat ctcccgggtg gcgtcgtcgc ccgtcatcgc
    11701 gaagcccgcg agtcggcgta cggtgctctg ctccccgtcg caccccacca catgggcggc
    11761 cgtgaggcgg tggctccttc cgccggggcc gaacgccacc acctccaccc ggtcgtcgtg
    11821 ctgtgtcagt ccggtgacca cgtgcccccg gcgtacctcg gcgccccgct ccacggccca
    11881 tgcctccagg acgggttcga ggcggctctg gaggcactcc cactggccgg cgtaggggtg
    11941 ccccgggtcc gcctcggcca gatcgaacgg gatcccgccg aaatgaccgc gcccaccggc
    12001 cgggagatca cccaaacggt cgaggatgcc cctttcggcg aggatctcca tggtccgcgt
    12061 gtggaggatc gaggcgcggg actcggcggt cggcccggac aactgctcca gtacgacggt
    12121 cctggcgccg ccggcgctca cctcgcccgc gagcagcagc ccgacgggcc cggcaccgac
    12181 gacgaggacg tcggcgtccg ctgagccgcc catccttcag cgccgcgctt ccgcgtagga
    12241 cttggcatgc cccagcgtcg cccggctgtt ggctcccagc gcctcacgca ggaaggtgcg
    12301 ggcctgcggg attccggcgt ccggtccgag gatccgcatg atgttctcgg tgttgatgac
    12361 cacggtgtgc cgggacgtcg cggtggtgac gccgtcactt ccctcgtcga accgccagct
    12421 gccggtgtgc agggtcatca gggcgggcag cgtggtctgc ttgtacacga tcccgtggtg
    12481 cgggaagcac actctgaccg actccgtggt gtgcgtggag ccgtccttcg cgaccgtgtc
    12541 catgcgcagg gtctggactc ccggttcgtc ctcggtcagc gagacccggg agacatgcgg
    12601 cagccgatcg gtccacagcc gggcctcgtt gacgaagtcg tacgcgtcct tggccgagcc
    12661 gttgatccgt acgctgtcct cgaaggtcag cgtcagctcg gcggagtgcg cggccagctc
    12721 cacattcgtc ttgagcgcgg cgagttcgga gcggctgttg cggtccacgg cccggtcgat
    12781 ccacgccagg cccgccgggt cgtcgtcgat ggcgcggtag gagtgcagca gccgcagccg
    12841 gcaccccgcc ccctgtggct cgatgatcca cgtaccgctc atctcggcga ccggcggcgc
    12901 ggaaacctcc tgaccgaagg tgatacgcag gcccgccggg tcgagccggc ggcgtgatgt
    12961 ccagttcttg gcctcgccgt tggccgtggc ccagatccgg atgcgctcct cgtcaccgtt
    13021 cttctccacg tagtcgacgt acaccgacgg cgggaagatc ctgggccagt tctccacctc
    13081 cgcgaggagg cggtagacct ccggggcagg ggcggacacg gtgatctcgt gctcgacttc
    13141 gcggggcgcc tgctcggtca tgttcatctc cttggcagtg gtgggcacat cgggtccggc
    13201 cggggagccg ggggccggcc gggtcagaag ttgccgaggc cgccacagac gttgagcgcc
    13261 tgcgcggtga tggacgccgc ggtgtcggag gtgaggtagc cgaccagacc ggcgacctcc
    13321 tccgcggtgg agtagcggcc gagcgggatc ttggcggtga acttctccag gatctgctct
    13381 tcgtcgacct cgtacgcggc ggcgtagccc tggcgcaccc gctgcgccat cggggtctcc
    13441 acatagccgg ggcacacggc gttgacggtg atgccggtcg gggccagttc gttgccgagc
    13501 gccttggtga agccgacgac accatgcttg gaggcggagt agggcgcacc caggacgacg
    13561 ccctgtttac cggccgtgga cgcgatgttg atgacgcgtc ccccgggcct gtcgcgcatt
    13621 ccgccggtgg tcagcacctc gcgcgtcacg aggaagacgc tgttgaggtt ggtgttgatg
    13681 acgtcgaacc acagctcgtc ggcgatgtcg gcggtgaccc cgccgccgct gcggcccgcg
    13741 ttgttcacca ggatgtcgat gggaccgaag cggccgacgg ctgcccggac caggtcccgg
    13801 atgtcgtcct tcgagcacac gtccgctgcc ctgccgtcca cctccagtcc ctcgccccga
    13861 agttccttga ccgttcgcga cacgtcgtcc tcggtgcgcg cgcacaggaa gaccttgtgg
    13921 ccctgtccgg ccagcagccg ggtggtggcc aggccgatac cgctggtggc accggtcaca
    13981 agcgcgacct tcactacgtc ctgcgtcatt ctgtgtctcc tggttccggg gggaggggag
    14041 cggctcagac ggcctgagcg gagggaagtt gcccgttgac gagagcgatc agcgcacgcg
    14101 gtgtgcgggc gtcggcgaag atctcctcgt cgaggctgat cccgtactcc cgctcgatac
    14161 ggccggcggt ctccagcatc gccagggact cgtaacccag cgcgtcgaac tccgcgtcga
    14221 gaatgtctcc gtcgaggtcg acgccctcgt cggcgccggc gccctcgcgc aggatggact
    14281 tgaggtcgtc gatggtgaag ggggtcgcgg gcatgagggt ccttcctcga aacgcatggg
    14341 tggagggctt gcgcatttcc gggccggtgg atcagtcgcg tggtgcgcgc accacgaccg
    14401 cggagttgaa tccgccgtag ccgcgggcga ttacgagcgc ggtgcgcacg ggtgtctcgc
    14461 gcggcgggcc ggtcaccaga tcgatgtcgt agtgagggga gagcgaggtg ttggtggtcg
    14521 gcgggatgac gccgtccctg atgctgagac aggcggtggc cacgtccagc ggggcggcac
    14581 ccgagtacag tcgcccggtc atggtcttgg gtgcggtcac gggtaccgcc cgggggccga
    14641 agaccttgct gatcgcctcg gcttcgaccc ggtcgagttc cggcaccgcg gccgcgtccg
    14701 cgaacaccac gtccacgtcg ccgggcgccg tttccccgtc gcacagcgcc tgttcgaccg
    14761 cccgtcgcag ccccgggccg cggtcgccgc ccggcgcggg gtcgaaggtg gaggcatggc
    14821 cggcgatctc ggcgtacacc tgccgtgccc cgcgggcgcg ggcgtggtcg gcgtcctcca
    14881 ggatgagcag cgctccgccc tctcccggta cgtgccccgc ggcgccgtcg tcgaagggca
    14941 cataggcccg cccgggatcg gtggcgcggc tgagccggcc gctcgcgagc tgggccaccc
    15001 agccccaggg gcagatcgag gcgtcgatgg ccccggagac gatcagcggt gtgcccttgc
    15061 ggatctgccg gcgggcctgg gccagcgcgt ccagaccgcc ggcctggtcg ctgacgacga
    15121 ccccgctggg gccgcgcata ccgttgcgga tcgagatctg gccgctgttg accgcgtaga
    15181 accacgcgaa ggactggtac gcgctcacat accggccgcc cttgctccac agcgcccgga
    15241 gttccttctg gccgaactcg aacccgccgg aatgactggc cgtgatcaca cccatgtcgt
    15301 acgcgggcag ggtgtccggt acgacccccg cgtcctccag cgcccagtcg gcgctgacca
    15361 gcgccagccg ggtcatccga tcggtctggg gcagcagccg gctgggcagg tggtcctcgg
    15421 cggcgaaccc ggctatctcc cccgccagtt gagcgggata ggacgtgggg tcgaaccggc
    15481 cgacccggcc gatggcgccc cggcccgcca gcacggccga ccagtaggac tccagaccca
    15541 gaccgttggg cgccgccacg ccgagtcccg tcaccacggt ggtggcgttc atcgcctcct
    15601 cctgtcgggc cgggccagca ccaccgcgct ctggaagccg ccgaagccac tgcccaccga
    15661 caacacggtg tccgtgcgcc gctccctggc ggtgaggggc gtgtagtcca ggtcgcactc
    15721 cgggtccggg gtgcggagat tggccgtggg cggaatgacg tggtgctcca tcgccagtgc
    15781 ggaggctgcg agttcgatgg agccgaccgc gccgagcgag tggccgacca tggacttgat
    15841 ggagctgacc ggtgtgcggt acgccgcctc gcccaggctc agcttgaagg ccgcggtctc
    15901 atggcggtcg ttctgcttgg tgcccgagcc gtgggcgttg atgtagtcga tgtcctccgg
    15961 gttgacgcgg gcctccgcca tggcgatgcg gatcgcctcc gccatctcct tgccgtcggg
    16021 gcgcagtccg gtcatgtgga aggcgttgga gcgcgtcgcg tagccggcca cctccgcgta
    16081 gacatgggcg ccgcgccgcc gggcgctctc cccgtcctcc aggacgaaga cggcggcgcc
    16141 ctcgcccagg acgaagccgt tgcggctcgc gtcgaagggc cgcgaggcgt gcgcgggatc
    16201 gtcattgcgc ggcgtggtcg ccttgatggc gtcgaagcag gccacggtga tcggtgagat
    16261 cggcgcctcc gtcgcaccgg cgatcatgac gtccgccgtg ccctccctga tcacctcggt
    16321 ggcgtagccg accgcgtcca ggccggatgt gcatcccgtg gagacgaccg aggcgggccc
    16381 ctcggcaccc atcgcgtggg ccacctcggc ggcgaaggag ctggggacca tgtagttgta
    16441 gaggtgcgga acggcgtact cgtggtcgac cagctcccgc cggccgccgt cgctgaccgt
    16501 ccggtactcc tcgtcgagcc ccatggtggc gcccacggcg ctgccgatgg tcacccccat
    16561 gcggcccgga tccagcgtgt ggaaggcaag cccgctgtcg gccgccgcct cgcgcgccgt
    16621 gaccaccgcg agctgcgcgg cgcggtccat gcgccggatc tcctgcgggc cgagaccgca
    16681 cgcctcggcg tcgaagtcca cttccgcggc gacctgggag cggaaggggg aggggtcgaa
    16741 gaacgagatc cgccgggtgg ccgtacgtcc gtcggtgagg agctgccaga accccttcgt
    16801 ccccggtccg cccggtgccg tgactccgat cccggtgatg acgacctggc gcccgtatac
    16861 ggcactcact cggcgctcca gtggtagaag cgccgcgcca tcgcgtcggc gggggagcgc
    16921 caggtcgccg ggtcgtacgc ctcgatgaac ggcttcagat cctggctgat cccgacgaac
    16981 cgcgggtccc ccttggtctg ttcgatccgc tcgccgccgt tctcaccgtc gaaatcctga
    17041 aggtggaagt agagcccccg gaacgagaag agctcgcgcc ggcgcgttcc catcagctcc
    17101 ggcatctccg taccgtcgaa ggcggagaag tgccgggcca cctcaccggc ggaaccgggt
    17161 tccatccggg cgacaatcaa tgtgctgtac atcctcgacc tctctctgcg cgtgggaacg
    17221 aagggcgttg cgtcatacgg cgcgtgtgtg cgccgtaccg tgctgccggg cggggccgaa
    17281 ccagcgctcc agggccatcg gcaggtcgtg gtggctgccg ggtgcgatcc aggcgacgtg
    17341 gccgtcgggg cgcagcagta cggcgctcgt cccgtcgagc ccgccgccga gggcggcagt
    17401 gccccgggga gcggcggtga ccaggtcgac acggtccgcc cagggggccg cgcgccgccg
    17461 cagccgcggc gtatcggcca ggtcgagcag cacgccccgg ccggcccgga gcagctcggt
    17521 gctggaggtg acggtggtgc cccgcaacag ctccaaccgc ggcatccgca tccccagcag
    17581 ggggttgggg ccgctcccga cgtcgtagcg gatgtccagt ccccccgcct tggccgcgaa
    17641 gtggcgggcg acctcctcgt accgcgccag ctcggtcagg atgtcgcgca gcggctgcac
    17701 ctcctcgctg ccgaggatca gcaggctctg ggcgcgggtg ttggcgagca gccgacggcc
    17761 gacctcgtgg cgttcggagt gatacgtgtc gagcagcgcg gggccggcgg cgccgtgcag
    17821 tacggcagcg agtttccagc ccaggttcac cgagtcctga acgctggtgt tcatcccctg
    17881 tccgccggcc ggaaggtgga tgtgggcgga gtccccggcc agcagcaccc tgccgcggcg
    17941 gtactcggtg acctggcgcg tggcgtcgcc gaaggcgctg agccacacgg gctcggcgtg
    18001 cgagatatcg atgccggtga gccgcttcca ggcgtcggcg acctcggcga aggcgggcgg
    18061 gcccgtcctc cgctgcggcg gcgcaccgcg ttcggcgacg atgacgcggt ggacgccgtc
    18121 cccgagccgg gcggtcatga ccatgccgtc ggtgacccgg tcggcgacca tgcgcggctc
    18181 cagatcgaca ccccggatat ccgcgaggag gagctcggtg gtggccgggg tgccggggaa
    18241 gtcgaagccg gcggccttgc gcacggcgct gcggcccccg tcgcatccga ccagaaaacg
    18301 gcagttcagg acctgttcgc ccgccgggcc gcgtacctgc gcctcgacat ggccgccgtg
    18361 gtccgtcagg ccggtgaact cgtggtcgcg gcggatgtcc gcgccgagtt cgcgggccca
    18421 gctctccagt acggattcgg tggcggactg cggcacggtc ctggcggccc ggtcgccacc
    18481 gcccaggaca ccgaaatcca ggggtattcc gccgaagtgc ccgaggccgc tcatctcgat
    18541 gtcgccgaag cgcggcaaca ggccacgctg gtcgaggact tccacggtgc ggggtgtgag
    18601 cccgataccc cgggactctc cggtgcgctg cgggagacgg tccaggacca ccacatcgat
    18661 cccggccaga cgcagctctc cggcgagcat cagacccgcc ggccccgctc ccacgaccat
    18721 gacggaagca tccattgtct ctcctcacgt ccttgctgac agcgccgtcg tgtgcttcgc
    18781 gcctgccggt caccgagtag tcccgcgggc cgtgctcagc tctttcgccc gatgaccaga
    18841 acgtcgtccg gtgtgtcctc gggaccgacc gtctcggggc ggaatccggc ctcttcgagc
    18901 cacgcgtggc agtcactgac cgggtactcg ccgccgcccg cggaccacac cagcatgctc
    18961 agcgcggcga gtgtcgcgta gagcggtggc gcgctgttgc tgaccatggg gtcgtagatg
    19021 atgaccgctc cccccggccg gatcgcgtcg tgcgccttgc gcagcagcgt gcggcgctcg
    19081 tccacacccc agttgtggag cacatgaccg aagatgagca catcggactc gggcagcggg
    19141 ccggcgaaga agtcgccgcc gtggaacgag accgccccgt cgtcgccgag ggcggccatg
    19201 tgggtggtga aggccccctc caactgcggc agatcgaaca ccgcgccctt cagatgcggg
    19261 ttgctcaggg ccagatggtg ggcgacgttg ccgcgcgcgc cgccgacgtc cacgaacgag
    19321 tcgtagccgc tccagtcgat ctcgcccagg cgccgcagga ggggcgtgtt gagtgtgtcc
    19381 atgctctcca ggaacgattc cgtcgattcc gggtcctggt agagggtttc gtacgggttg
    19441 ccctccaccg cggcgggatt ctgtggggcg cccgtgcgta gcgccgtccc gagaccttcc
    19501 caggccgggt tcagctcgcg ctcacagaac tggaggtagc cgccgatgaa ttccggccgg
    19561 gcgcgcacca gataccggtc ggcggcaggg gagttacgga actctccggc ctccgaggcg
    19621 tccagcagtc ccatcccggc gagggccaga aagaagtcac tggctcccgg catgcggtac
    19681 ccgagccgag tgctcagttc ctcggcggtg gccgaggaac cggacaattc ggtgaagaga
    19741 ccggactcca cggcggtaag cagaatcttc gtctgccaga atccggtcaa tggtcccatg
    19801 acctgaccga taaatggctc ttccggctcc ggaaccgcat ttttctggtc gctcatacga
    19861 ggcccctcca aggagtagca ggacaactcc gaatccgaac ggatcgtggt tcggttgccg
    19921 agtcctgtgg atcctcgcag cggccgtcca agaaacgacc aaaagccgct caaagtgaac
    19981 gcagaattac ggaaatgagc agaatgcaat cagccggaaa cggaggcgtg caagagggcg
    20041 cgggcgcgct gaaggccggg cccgcacatg gtgcggaccc ggccttcact accgcgcttt
    20101 cggctgcgcg ttctcagttc cgattcttca cccgcaggcc gctatgggtg cgccatggcg
    20161 gagccgtccg cggacgacgc ctcggcctgc accgcggtcg gggcctcggg gcggccgggc
    20221 agcagcggag aggcggcgag aatcaccagg gtgaccgcga aaacgaacca gtacgcgccg
    20281 tggaagccac cgatcccggc gccgccggcc gcggcgccat ttccgacggc cgccaggatc
    20341 agggcgacac acgcgacccc gagcgcgccg cccaactggt tgaggttgta gacgacggaa
    20401 ctgccctgcg gcaccttctc cggcggtagc gtccggtaca gcgaacccat ggtcggcgcg
    20461 ccgacgccgc ccaggcccag gccgacggcg aacgcggcca gcacggacca gacttcaccg
    20521 ctgtccgcac cgatacgggt gaggccgacc gaggcgagcg ccgccacgac cgctccgccg
    20581 cgtacgagat tgcgcgctcc cagccggtcg ctgaggcggc cggcgatagg catggcgagc
    20641 gccgatccca ggcccagcgg cgccaccagc agtccggccg cgcgggcgcc gtgtccgtgc
    20701 agcacctggt agtagagcgg cagggcgaac aggacggcga acgtggccag tccgacgagc
    20761 ccctgcacgg tcacgctcgc ggcgaagctg cggctgctga acagccggat gtcgatcagc
    20821 ggttcggtgc ggcgggctcg cagcgcgtgg atcacgtacc cgacgagcag cgcgacgccc
    20881 agggccagcg ggatgagcac ggagggcacg gcgaaccggg cgcgctcgcc cgcctccgtg
    20941 agggcgagca ggatcgccgc gagacccgga gccatcaaca gggcgccgat gatgtcgaga
    21001 cggggcccgg acccgcgctt gaggggcgcg ccgaccggga tcacccgcag cgcgagcagg
    21061 accgcgacga tcccgatggg caggttgatg tagaacatcc agcgccagcc catggattcg
    21121 agcacgaccc cgcccagcac gggcccgagg accggcccga gcgacaggac cacgcccatc
    21181 atgcccatca cgcgccccgc ccggctgggg cccgctgcac gggccaggat caccaggacc
    21241 agcgggtcga cgacaccggc gcccacaccc tggacgaccc ggaaggcgac caggctctcc
    21301 acgttccagg cgagggcgga ggcgagcgaa ccgaccagga acagcaccag tccgaaaagc
    21361 cagagcttcc tgacgccgaa ccggcccacc gcccagctcg tgatggggat ggtgaccgtg
    21421 agcgccagca gatagccggt cgtggcccaa ctgatggaac tcagcgaggt gttgaactcc
    21481 gccgcgaggg tgtcggccgc gacggtgacc atcgtgctgt cgaggatccc catgatcccg
    21541 cccagcaggg tcaccccgat gagccgtaac agcccgggat ccagccggtc atctctgact
    21601 tgagacatca ctttccaact ccgttaagag cgacacacga acacgtgttg aaccaggcgg
    21661 ttcaatataa cgacccgcca tgacctcctg caaccaactc gcccagaaag ttgaaccgcc
    21721 cggttcatat atggggttga cgcggtacga tggcggcgtg aacggagcca agacctcaag
    21781 cgcgagcaga cgcgaggcgc cgcgcgggcg catcgacaag cggcaggcga tcctcgaagc
    21841 cgcgttcagg acgttcgccc gcgaggggta cggacagtcc tgcgtacggg agatcgcggc
    21901 cgaggcgggc gtggccaagc ccaccatcta caaccacctc ggggacaagg agacgctgtt
    21961 ccgcgaggcg atgctggccg ccgtcggccg tacgagcggc gcggggctcg gggcgctcga
    22021 acagctccgg gagcctgacg gtgatgtgcg ccccatgctg gaggaagccg gcctccgcat
    22081 tctgaagaac cactgcgacc cggagtcgca ggcgctgcgc tggctcctca acgccgaagc
    22141 ggcgcggttt cccgacctgt tggagaccat ccagcgcgag ggcgcgcagc gcctccacga
    22201 cgcgctcgcc gaccgcctgg cacgcttcgc gctctccggg cgcctgcaca ccagcgaccc
    22261 ggacctggcc gccgagcagt tcctcgcgct gctcacgggc ccgatggcgc tgcgcacccg
    22321 gctcggcacg cgcaaggtgt ccgacgccga actgcgtgcc gtggggcggg ccgcggtcga
    22381 cacgttcctg cgcgcctacg ctccccggac cgtggacact ccgtagacgc ccaggacgac
    22441 cagggcaggg gcccggagaa gcggcacgga gaagcggcac ggaaaagggc acggagaagg
    22501 ggcgcagagc agagcacgag gggcggggac gagaggcggg ccatgaccac gacactgatc
    22561 accggcgcca acaagggcct cggatacgag accgcccgac gcctgaccga ggcgggccac
    22621 accgtcctcc tcggggcacg cgacccccgg cgcgggcgag cggcggccga gcggatcggc
    22681 gcccgtttcc tcccgctcga cgtgaccggc gaggagtccg tcctggcggc gtccgaccgc
    22741 gtccgcgagg agttcgggca cctggacgtc ctcgtcaaca acgccggaat caccggcccc
    22801 cgcaaggagg ccgcggagct gacggccgac gacatcaaga agctctacga caccaatgtg
    22861 ttcggagccg tccgggtcac ccgcgcgttc ctgccgctgc tccgggccgg tgagtcgccc
    22921 accgtggtga acgtcagcag cggactggga tcgctggcca tcgccgccga tcccgagcgc
    22981 ttcgagtcgc tgcttcccgt gtactacccg agcctgggct acaactcctc caaggccgcc
    23041 ctgaacatga tcaccgtgca gtacgcgaag gccttcccgg agatcacgtt caacgccgtg
    23101 gacccgggct ggaccgccac cgacctgaac gaccaccggg gcgtccagac cgtcgaggag
    23161 ggcgccgcgg tgatcgtccg gatggccacg ctcggaggcg acggccccac cggcggcttc
    23221 ttcgggaaca ccggccccgt cccctggtga ctccggtgcc ccggcagccg cgccgtcgat
    23281 cccggtgcgg tcacccctcc gggccccgtg gaccggcggc ttcaccgggc gtccgcgttc
    23341 cacccaccga tccgggcgcc ggcagggcga tgagaccggc cgccgcggcc tgggtcaccg
    23401 cgtcgagccg ggagacggcg tccagtttgc ggaaggccgc gtgcagatgc cgtttgacgg
    23461 taccggtcgt gatgcccagg ctgctggcca cctgctggtt ggtcatggcg gtggccactc
    23521 cacgcagcac ctgcgtctcg cggggcgaga gcgcggggac cgaccgctgg acggcgttcc
    23581 gcaaggccgc gggagcgagc gagcgtaccg ccgcgagcag ggcgtcccag cccgcgtccc
    23641 gcggcaggta tctgtgcacc cccgccgcct ccagggcgcg ccggtcgatc agcgcgccgc
    23701 gcgccggcag cgcgagcacg gccgatctcg gggtgaggcg gcgcagcgag cggacggtgc
    23761 ggatgacggc gctcccgtcc gcccatggct ccacgaggat cacatggggg tgcagggccg
    23821 ctgccctgca caggatctcg tgttcgccgg tggcctggcc gaggacacag atatcggcct
    23881 gggtgtggaa aagccctgtc agtgcgtcgc gcagtaaagc ggtctcgccg gcgacgagga
    23941 cggagatatg aggcat
//
