BGC0002483 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002483 (Cladonia uncialis subsp. uncialis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	47,950	usnic acid	PKS	100%

BGC0002483 - Region 1 - T1PKS

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Location: 1 - 47,950 nt. (total: 47,950 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 47,951
Label		BGC0002483

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002483	1.00	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0001219	0.40	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0000099	0.39	Polyketide	monascorubrin	Talaromyces marneffei
BGC0002429	0.30	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0002427	0.29	Terpene, Polyketide	subglutinol A, subglutinol B	Metarhizium robertsii ARSEF 23
BGC0002603	0.29	Polyketide	chevalone E	Aspergillus versicolor
BGC0000154	0.28	Polyketide	stipitatic acid	Talaromyces stipitatus ATCC 10500
BGC0001976	0.28	Terpene	eupenifeldin	Phoma sp.
BGC0001338	0.28	Polyketide	citrinin	Monascus ruber
BGC0001827	0.26	Polyketide	xenovulene A	Sarocladium sp. 'schorii'

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002483	1.00	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0001219	0.72	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0000099	0.71	Polyketide	monascorubrin	Talaromyces marneffei
BGC0002429	0.64	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0002427	0.63	Terpene, Polyketide	subglutinol A, subglutinol B	Metarhizium robertsii ARSEF 23
BGC0002603	0.62	Polyketide	chevalone E	Aspergillus versicolor
BGC0000154	0.62	Polyketide	stipitatic acid	Talaromyces stipitatus ATCC 10500
BGC0001976	0.62	Terpene	eupenifeldin	Phoma sp.
BGC0001338	0.61	Polyketide	citrinin	Monascus ruber
BGC0001827	0.60	Polyketide	xenovulene A	Sarocladium sp. 'schorii'

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 47950:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AUW31052.1

PKS_AT (914..1204): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 54.0
Methoxymalonyl-CoA: 45.1
Methylmalonyl-CoA: 35.8
inactive: 30.6
CHC-CoA: 20.1
Propionyl-CoA: 18.7
Isobutyryl-CoA: 18.4
Benzoyl-CoA: 18.2
Ethylmalonyl-CoA: 16.1
fatty_acid: 15.6
2-Methylbutyryl-CoA: 14.9
3-Methylbutyryl-CoA: 14.2
trans-1,2-CPDA: 14.1
Acetyl-CoA: 12.5