LOCUS       BGC0002490              5965 bp    DNA     linear   BCT 06-FEB-2015
DEFINITION  Yersinia pestis CO92 complete genome.
ACCESSION   BGC0002490
VERSION     BGC0002490
KEYWORDS    .
SOURCE      Yersinia pestis CO92
  ORGANISM  Yersinia pestis CO92
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Yersinia.
COMMENT     On or before Sep 27, 2006 this sequence version replaced
            AJ414141.1, AJ414142.1, AJ414143.1, AJ414144.1, AJ414145.1,
            AJ414146.1, AJ414147.1, AJ414148.1, AJ414149.1, AJ414150.1,
            AJ414151.1, AJ414152.1, AJ414153.1, AJ414154.1, AJ414155.1,
            AJ414156.1, AJ414157.1, AJ414158.1, AJ414159.1, AJ414160.1.
            Notes:
            Details of Y. pestis sequencing at the Sanger Centre are available
            on the World Wide Web.
            (URL, http://www.sanger.ac.uk/Projects/Y_pestis/)
            Original CON assembly
            join(AJ414141.1:1..288050,AJ414142.1:51..214050,
            AJ414143.1:51..201050,
            AJ414144.1:51..208050,AJ414145.1:51..208050,AJ414146.1:51..210050,
            AJ414147.1:51..199050,AJ414148.1:51..210050,AJ414149.1:51..193050,
            AJ414150.1:51..335050,AJ414151.1:51..334050,AJ414152.1:51..313050,
            AJ414153.1:51..258050,AJ414154.1:51..204050,AJ414155.1:51..205050,
            AJ414156.1:51..220050,AJ414157.1:51..216040,AJ414158.1:41..235050,
            AJ414159.1:51..199050,AJ414160.1:51..203728).
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 09:56:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5965
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1137
                     /codon_start=1
                     /db_xref="InterPro:IPR002491"
                     /db_xref="UniProtKB/TrEMBL:Q7CHH1"
                     /inference="similar to sequence:INSDC:AE001704"
                     /inference="similar to sequence:INSDC:U52150"
                     /locus_tag="YPO1343"
                     /note="Similar to Vibrio cholerae vibriobactin and
                     enterobactin periplasmic binding protein ViuP TR:Q9RCF6
                     (EMBL:U52150) (325 aa) fasta scores: E(): 0.00051, 25.9% id
                     in 259 aa, and to Thermotoga maritima possible iron(III)
                     ABC transporter, periplasmic iron-binding protein TM0189
                     TR:Q9WY32 (EMBL:AE001704) (358 aa) fasta scores: E():
                     0.0025, 24.9% id in 374 aa"
                     /product="putative periplasmic binding protein"
                     /protein_id="CAL19995.1"
                     /transl_table=11
                     /translation="MIHYNITIKSTRISFMLLRIFWSLCLWWGISSSALAEIHLKDVDG
                     REVTLAAPAQRVYIGFYYEDFLAINGPDSYQHVVAFSKSDWSLRTSQWPRYQAALRRLS
                     QLVDVGSLYNQSFDFERLLATRPDLLILAKWQLEGFANYLPVLQQLSIPYVVVDFNQGE
                     DAKLTSIRVMGQALGHGERAERLAIAYQQGIADIRRRITQANLPSPKTYIELGDKGPGE
                     YSSSYGSSIWGPLLQQAGANNIATGVVTTPSPLRAEYVLSQKPEVIFLAGGDWPKMPNA
                     VSMGFGAKPETLQQSMTQYAQRPGWSQFPAIKQTRFYALYHGGVRTLYDYIFVQFVAKA
                     LFPSAFEDVNPQHNLETFYEEYLPIKADGVFMQQWQGE"
     subregion       1..5965
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002490"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5965
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1137
                     /locus_tag="YPO1343"
     misc_feature    223..969
                     /inference="protein motif:PF01497"
                     /locus_tag="YPO1343"
                     /note="Pfam match to entry PF01497 Peripla_BP_2,Periplasmic
                     binding protein, score 3.20, E-value 0.00018"
     gene            1288..2193
                     /locus_tag="YPO1344"
     CDS             1288..2193
                     /codon_start=1
                     /db_xref="GOA:Q0WH71"
                     /db_xref="InterPro:IPR000522"
                     /db_xref="InterPro:IPR029022"
                     /db_xref="UniProtKB/TrEMBL:Q0WH71"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 135.1; E-value: 4.5e-41)"
                     /gene_kind="transport"
                     /inference="protein motif:TMHMM:2.0"
                     /inference="similar to sequence:INSDC:AF109162"
                     /locus_tag="YPO1344"
                     /note="C-terminal domain similar to C-terminal region of
                     Corynebacterium diphtheriae putative iron acquisition
                     protein HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta
                     scores: E(): 7.4e-17, 36.7% id in 169 aa, and to
                     Methanococcus jannaschii putative ABC transporter permease
                     protein Mj0087 SW:Y087_METJA (Q57552) (349 aa) fasta
                     scores: E(): 3.4e-20, 36.2% id in 185 aa"
                     /product="FecCD transport family protein"
                     /protein_id="CAL19996.1"
                     /transl_table=11
                     /translation="MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLV
                     DANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLPAHL
                     LSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGV
                     LMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSF
                     VGTIGFIGLVAPHFARMLVGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGII
                     IALIGVPVLFYFVTKQVKRA"
     misc_feature    1483..2175
                     /inference="protein motif:PF01032"
                     /locus_tag="YPO1344"
                     /note="Pfam match to entry PF01032 FecCD_family, FecCD
                     transport family, score 64.60, E-value 2.1e-15"
     misc_feature    1927..1995
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1344"
                     /note="one of 3 probable transmembrane helices predicted"
     misc_feature    2029..2097
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1344"
                     /note="one of 3 probable transmembrane helices predicted"
     misc_feature    2110..2169
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1344"
                     /note="one of 3 probable transmembrane helices predicted"
     gene            2190..2975
                     /locus_tag="YPO1345"
     CDS             2190..2975
                     /codon_start=1
                     /db_xref="GOA:Q7CHH2"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:Q7CHH2"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 156; E-value:
                     2.1e-47)"
                     /gene_kind="transport"
                     /inference="similar to sequence:INSDC:AL445963"
                     /locus_tag="YPO1345"
                     /note="Similar to Escherichia coli ferrichrome transport
                     ATP-binding protein FhuC SW:FHUC_ECOLI (P07821) (265 aa)
                     fasta scores: E(): 2.7e-22, 32.8% id in 259 aa, and to
                     Streptomyces coelicolor Fe uptake system permease FtrE
                     TR:CAC14366 (EMBL:AL445963) (272 aa) fasta scores: E():
                     8.8e-22, 34.2% id in 260 aa"
                     /product="putative transport ATP-binding protein"
                     /protein_id="CAL19997.1"
                     /transl_table=11
                     /translation="MTQLTLKHVGVTLHKRPLLTDISLTWPAAQVSGIIGPNGAGKSTL
                     LKAINHMVPITGQIEYQQCPLNTRVTRIAYVSQLNRSDSALTVFEMVLLGKVRQLSWRV
                     SPAQIDAVEQVLAECGISSLANQVFNSLSGGQRQLVMLAQAFIAQPQIILLDEPTSALD
                     IHHQLRVLQKIVDYSKRHQCTTLMVIHDLGLALRFCQTLTLIHRGNVACHGAAHQVIAD
                     PMMSTVFGVGIESGTSPLGYRYLLPTQFLPTHGEKICIR"
     misc_feature    2274..2813
                     /inference="protein motif:PF00005"
                     /locus_tag="YPO1345"
                     /note="Pfam match to entry PF00005 ABC_tran, ABC
                     transporter, score 151.00, E-value 2.1e-41"
     misc_feature    2295..2318
                     /inference="protein motif:ProSite:PS00017"
                     /locus_tag="YPO1345"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)."
     misc_feature    2583..2627
                     /inference="protein motif:ProSite:PS00211"
                     /locus_tag="YPO1345"
                     /note="PS00211 ABC transporters family signature."
     gene            2972..3760
                     /locus_tag="YPO1346"
     CDS             2972..3760
                     /codon_start=1
                     /db_xref="GOA:Q0WH69"
                     /db_xref="InterPro:IPR004298"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q0WH69"
                     /inference="similar to sequence:INSDC:AE004896"
                     /locus_tag="YPO1346"
                     /note="Similar to Pseudomonas aeruginosa hypothetical
                     protein PA4836 TR:AAG08221 (EMBL:AE004896) (263 aa) fasta
                     scores: E(): 4e-21, 34.4% id in 259 aa"
                     /product="conserved hypothetical protein"
                     /protein_id="CAL19998.1"
                     /transl_table=11
                     /translation="MMKADVLAQLAGLQQEISQLHDNAQQNQSHFVLLERRFSRLQSFN
                     DEPQLQDYRLQLEHDDAVVKQIAQLRQVANAALCDYEKHQVCALCSPSSKTDDYLTSFN
                     QSLQQEIKLAGMQMGEKVLLVGSGALPTTALVLVAKLGATVFCYDHDPAAQQLARQLVQ
                     SLGLEKQVQFIDNLKELTDRPVDHIIVASLVADKQALLAQLVPYVTRSSKLVMRYGNGL
                     KSIFNCPYCHEVNCSHWRTASKPVTTGLYDLIILEPNHHA"
     gene            3753..5123
                     /locus_tag="YPO1347"
     CDS             3753..5123
                     /codon_start=1
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR016935"
                     /db_xref="UniProtKB/TrEMBL:Q0WH68"
                     /inference="similar to sequence:INSDC:AE004896"
                     /inference="similar to sequence:INSDC:AP001514"
                     /locus_tag="YPO1347"
                     /note="Similar to Pseudomonas aeruginosa hypothetical
                     protein PA4835 TR:AAG08220 (EMBL:AE004896) (433 aa) fasta
                     scores: E(): 0, 40.0% id in 447 aa, and to Bacillus
                     halodurans hypothtetical protein BH2073 TR:Q9KB58
                     (EMBL:AP001514) (436 aa) fasta scores: E(): 3.7e-26, 30.0%
                     id in 414 aa"
                     /product="putative exported protein"
                     /protein_id="CAL19999.1"
                     /transl_table=11
                     /translation="MHNTLPTLILGAGPAAIQLAVDISATGDARLGLYNRPSTKGERLK
                     QYLALTPTLYLQGTGKAQATQKESSVTIDCYIDQLAQAVGDWQRLILAVPADHYYAVLQ
                     QIPWAALPQLKSVILLSSSMGSGLMVQNLLNAAGKRDVEVISLSSYYADTKYIRAETQD
                     ISANTQDINAGTQDIGAIQPYRAYTKAFKQRIYLANQWGNAGSAEMSWLTAVLARHHID
                     TLPCSNLLAAERFSITNYVHPPLALADTTLQALFYPEQRSQYLYKTQPEGPVCPAVIAD
                     LAGLADDYKRLLNRLGVEEINLLRFLNDDNYPVPASMVSRRWIDEFPQLPPLEQQYALF
                     VRYTALLVDPYSTPDEQGRFYDFSAVKVATVYQDANALWHLPRVPLEDVHKLRTLLLLA
                     GALDVVMPTAQRLLQRFQQALKAFIDRVGEEHCHPSLLGDDCDRQAAIIEQQWRSQT"
     gene            5120..5965
                     /locus_tag="YPO1348"
     CDS             5120..5965
                     /codon_start=1
                     /db_xref="GOA:Q0WH67"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="UniProtKB/TrEMBL:Q0WH67"
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 74; E-value: 2.2e-22)"
                     /gene_kind="transport"
                     /inference="protein motif:TMHMM:2.0"
                     /inference="similar to sequence:INSDC:AE004691"
                     /inference="similar to sequence:INSDC:AE004896"
                     /locus_tag="YPO1348"
                     /note="Similar to Pseudomonas aeruginosa hypothetical
                     protein PA4834 TR:AAG08219 (EMBL:AE004896) (284 aa) fasta
                     scores: E(): 0, 55.7% id in 280 aa, and to Pseudomonas
                     aeruginosa hypothetical protein PA2628 TR:AAG06016
                     (EMBL:AE004691) (296 aa) fasta scores: E(): 6.6e-28, 33.2%
                     id in 283 aa"
                     /product="putative membrane protein"
                     /protein_id="CAL20000.1"
                     /transl_table=11
                     /translation="MNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLL
                     IGLLMYQRGIAFSREDRPLLVLRGTMGALYLICYFYSIAHLTLADASMLAYLSPFFSIV
                     LSLLVLRERVNATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFAAIAYLSVN
                     KLTKRHHNYEIVFYFLFITTLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQA
                     FSSDNLIVVSVVRYIGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA
                     "
     misc_feature    5156..5521
                     /inference="protein motif:PF00892"
                     /locus_tag="YPO1348"
                     /note="Pfam match to entry PF00892 DUF6, Integral membrane
                     protein DUF6, score 62.70, E-value 7.6e-15"
     misc_feature    5222..5290
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5309..5377
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5390..5449
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5468..5527
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5537..5605
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5576..5941
                     /inference="protein motif:PF00892"
                     /locus_tag="YPO1348"
                     /note="Pfam match to entry PF00892 DUF6, Integral membrane
                     protein DUF6, score 27.20, E-value 0.00038"
     misc_feature    5639..5707
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5720..5788
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5801..5869
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
     misc_feature    5882..5941
                     /inference="protein motif:TMHMM:2.0"
                     /locus_tag="YPO1348"
                     /note="one of 9 probable transmembrane helices predicted"
ORIGIN
        1 ttgatacatt ataacataac aatcaaatca acgagaatat cctttatgtt attacgtatt
       61 ttttggagtt tatgcctctg gtgggggatc agcagcagtg cgctggcaga gatccatctc
      121 aaagatgttg atggtcgtga ggtcactctg gcggcaccag cacaacgtgt ttatatcggt
      181 ttttattatg aggatttttt ggcgatcaat gggccagaca gttatcaaca tgtcgtggcc
      241 ttctctaaaa gtgattggag cctacggacc agccaatggc cgcgctatca ggcagcccta
      301 cggcgtttaa gccaattggt ggatgttggg tctttgtata accaaagttt tgactttgag
      361 cgcctgctgg cgacccggcc agatttactg attttggcaa aatggcaact cgaaggtttc
      421 gccaactatt tgccggtatt acagcaactc tctattccct atgtcgtggt cgattttaat
      481 cagggagagg acgctaagct caccagtatt cgggtaatgg ggcaagcatt aggtcatggc
      541 gaacgggctg aacgcttggc catcgcctat caacaaggca ttgcagatat tcgcagacga
      601 attacccaag cgaatttgcc ctcgccgaaa acctatattg aactcggcga taaagggccg
      661 ggtgaataca gcagcagcta tgggtcgtct atttgggggc ccttgcttca acaggccgga
      721 gccaacaata tcgcgacagg cgtggtcacc acgccttccc cactgcgcgc agagtatgtg
      781 ttatctcaga aacccgaggt aatttttctg gcgggcggag actggccgaa aatgccgaat
      841 gcggtgtcga tggggtttgg tgccaaacct gaaaccctcc agcaaagtat gacccaatat
      901 gctcagcgtc ccggctggtc acaatttccc gcgattaaac aaacacgttt ttacgcgctc
      961 tatcatggcg gcgtccgcac gttgtacgac tacatttttg tgcagtttgt cgccaaggcg
     1021 ctttttcctt cggcgtttga agatgtgaac ccgcaacata atctcgaaac gttttatgaa
     1081 gagtatctgc ccatcaaagc cgatggcgta tttatgcagc aatggcaggg agaataatgg
     1141 caaccttttt agagcccatc acgcagggac ggcaatcttt tcagcaactt catctacgac
     1201 gcgggttatt cacactggca ttgatcggct cgctactggc cgctatggtc atcgatctgg
     1261 ccactggcgc ggccaacctt agcccacttg atgtattgcg actgtttctg gtggattctt
     1321 cgcagcatga tgaactacac cagatcattt ttggtccatt cgtttgccga tgacgttaac
     1381 cgccgtggtg gtgggcgcga gtttgggttt ggctggcttg ttgatgcaaa ccgtactggc
     1441 gaatccgtta gccagtcctt ataccttggg gatttcagcc gcggcaggat ttggtgccgc
     1501 attatcgatc atcactggct tcagcgtggg gggagtcttg tcattaggca ccccattatt
     1561 ggcttcactg atggcattac tggcctgcct gcccatttac tttctgggcc aacggcaggg
     1621 gatgacaccg caaattctgg tgttgagcgg cattgtggtg ctgttcttct tccagtcgtt
     1681 gcaatcactc atgttatttc ggcctcacca gaagcgatgc aacaaattgt attctggctg
     1741 tttggcagcc tgctaaaagc caatatgcag ggggtgctaa tgacgggcag cgtactggct
     1801 tgttcactgg ttatctgttt gcagcaggca tggcgattga ccgcgctttc agcgggggag
     1861 gagcaagcgc taggtttggg gattaacgta agcgccttac gtaagttagc gtttcttctg
     1921 gcgaccttgt tgaccgccgc ctctgtgtct tttgtcggca ctatcggctt tatcggtttg
     1981 gtcgcccctc acttcgcccg tatgttggtc ggcgaagatc aacgctatct gatcggtatt
     2041 tcggcacttt gtggcagcct gctattggtt ctggcctcta tcatttccaa actcatactg
     2101 ccaaatggtg tcgtgccgat cggcattatt attgcgctga tcggtgtccc ggtattgttc
     2161 tattttgtga ctaaacaggt gaaacgggca tgacgcaact gacgttaaag cacgtcggcg
     2221 tcacgcttca taaacgccca ctgctcaccg atatttctct aacgtggcct gcggcacagg
     2281 tgagcggcat tattggcccc aatggggcgg gcaaatccac gttactcaaa gccattaacc
     2341 acatggtccc cattaccggg cagatcgaat atcaacagtg cccactgaat acgcgcgtca
     2401 cacgcatcgc ctatgtgtcc caactcaatc gtagtgattc tgccctgacc gtttttgaaa
     2461 tggtcctgct gggtaaagtt cgccaattga gctggcgtgt cagccccgca caaattgatg
     2521 cggtcgagca ggtattggca gagtgcggca tttcctctct ggcaaaccaa gttttcaaca
     2581 gtctaagtgg cgggcaacgc cagttagtga tgctcgcgca ggctttcatc gctcagccgc
     2641 agatcatttt gctggatgaa ccgaccagcg ccctggatat tcaccaccaa ttacgtgtgc
     2701 tgcaaaaaat cgtcgattac agcaaacgcc accaatgcac cacattaatg gtgatccacg
     2761 atctgggctt ggcgctgcgc ttttgccaaa cgctcacgtt aatccaccgt ggaaatgttg
     2821 cctgtcatgg cgcagcccat caggtgatcg cggaccccat gatgtccacc gtatttggtg
     2881 tgggtatcga aagtggaaca agccctttgg gctatcgcta cttattgccc actcagttct
     2941 tacctactca tggagagaaa atatgtatac gttgatgaaa gccgatgtgc tggctcaact
     3001 cgcggggctg cagcaagaaa tcagccagtt acacgataat gcccagcaaa atcagtctca
     3061 ttttgtgttg ttagagcgcc gttttagtcg cttgcagtct tttaatgacg agccacagct
     3121 acaagattac cggttgcagt tggagcacga tgatgcggtg gtaaaacaaa ttgcccaatt
     3181 gcggcaggtc gccaatgcgg cactgtgtga ctatgaaaaa catcaggtat gcgccttgtg
     3241 tagcccatcc tccaagactg acgactacct gacaagtttt aaccaatcgc tgcaacaaga
     3301 gatcaaactc gccggtatgc agatgggtga gaaggtgttg ttggtgggca gcggtgcctt
     3361 gccgaccacg gcgctggtac tggttgccaa gctcggtgca accgtctttt gctacgatca
     3421 cgatcccgcc gcacagcagt tagctcgcca gctcgttcaa tccctcggtc tggaaaaaca
     3481 ggtgcaattt attgataacc tgaaagagtt aacggaccgt cccgttgacc acattatcgt
     3541 cgcttcattg gtggcggata aacaggcgtt attagcacaa ttggttccct atgtgacccg
     3601 gtccagcaaa ttagtgatgc gctatggcaa tgggctgaag tctattttca actgccctta
     3661 ttgccatgag gtgaactgtt cacattggcg caccgccagt aaaccggtga ccaccgggct
     3721 ttatgacctt atcattttgg aacctaatca tcatgcataa caccctgccg accttgattc
     3781 tgggggccgg gcctgcggct atccaacttg cggtggatat tagtgctaca ggtgatgcta
     3841 ggttggggct ctataatcgg cccagcacga aaggcgaacg gttaaagcag tatctggcac
     3901 tcacgccgac cctttatttg cagggtaccg gcaaggcaca agcgacccag aaagagagca
     3961 gtgtcacgat tgattgctat atcgatcaat tggcgcaggc ggttggtgat tggcaacgtt
     4021 tgattctggc agtccctgcc gatcactatt acgccgtcct acaacagatt ccgtgggccg
     4081 cgttaccaca attaaagtca gtgattttac tgtcctcttc gatgggttcc ggcctgatgg
     4141 tgcagaatct gttaaacgcc gcggggaagc gcgatgtcga ggtcatcagc ctgtccagtt
     4201 attatgcgga tactaaatat attcgcgctg aaacccaaga cattagcgct aatacccaag
     4261 acattaatgc tggaacccaa gacattggcg ctatacagcc ttatcgggcg tataccaaag
     4321 catttaaaca gcggatatat ctggccaatc agtggggtaa tgcgggatcg gcagagatga
     4381 gctggttaac ggcggtatta gcccgccacc acattgacac cttaccgtgt tctaacttgt
     4441 tggccgccga gcgttttagc attaccaatt atgtccatcc tcctttggcg ctggcggata
     4501 ccacgttgca ggcgctgttc tatccagagc aacgtagcca gtatctgtat aaaacccaac
     4561 cagaagggcc ggtctgtccg gcggtgattg cggatttagc gggtttggcc gatgactata
     4621 aaaggctcct caaccggcta ggggtggaag aaatcaactt gctacgtttt ctcaatgacg
     4681 ataactatcc ggtgcctgcc tccatggtca gtcgtcgctg gattgacgaa tttccacagc
     4741 ttccccctct tgagcagcaa tacgcactgt ttgttcgtta taccgccttg ttagtggacc
     4801 cgtactctac accggatgaa caaggccgat tctatgactt ttcggcggtc aaggtggcca
     4861 cggtatatca agacgcgaat gcgctgtggc atttgccgcg agtgccgctg gaggatgttc
     4921 acaaattgcg aacgctgcta ttactggcgg gcgcgctgga tgtggtgatg cccacagcgc
     4981 agcggctgct acagcgattc cagcaggcgc tcaaggcgtt tattgaccgg gtcggtgagg
     5041 aacattgcca tccctcttta ttgggggacg attgtgacag gcaggcggcc atcatcgaac
     5101 aacaatggcg gagccagaca tgaaccaagg cgcgttattg gctattctcg cctccctgat
     5161 tttcagcgtg atgaatgtgt tagtcaaaac catcgctgat gaaattccta ccggtgagat
     5221 cgtattcttc cgcagtagca ttggttgctt gttgattggg ttactgatgt atcagcgtgg
     5281 gatagcgttc agccgtgaag atcgcccatt gttggtactc cgggggacga tgggcgcact
     5341 gtatctgatt tgctattttt acagtattgc tcacctgaca ttggcagatg ccagcatgtt
     5401 ggcctatctg tcaccgtttt tctcgattgt gctgtcatta ttagtgttgc gcgaacgggt
     5461 gaatgccacc atggctttct ggttggtgat ggtgattatt ggcgcgatta tcttgatccg
     5521 cccgtggaat ttttccacct atacgttggc gtctctggtg ggggtgatga gtgcggtatt
     5581 tgcggctatt gcttatttgt cggtgaataa gctcacgaag cgccatcaca attatgaaat
     5641 cgtcttctac tttttgttta tcacgacgct gatctctatc ccactgatgt ggcataactt
     5701 tgtttggccg agtgggtatc agttcggcat tctcatcgcc attgctcttg tctcattgct
     5761 aggtcaggtg gttttaacgc aggctttctc ttcggacaac ctgatcgtgg tgtcggtggt
     5821 gcgctatatc ggcattgtct tcaatattac ctggggctgg ctattttggg atgaggtgcc
     5881 attgatgttg tcgttgatgg ggggcgggtt ggtggtggta tcgtgcattc agttggggtt
     5941 acgcagtaaa aagaaggcgg cctga
//
