LOCUS       BGC0002492             13803 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Myxococcus xanthus DK 1622, complete genome.
ACCESSION   BGC0002492
VERSION     BGC0002492
KEYWORDS    .
SOURCE      Myxococcus xanthus DK 1622
  ORGANISM  Myxococcus xanthus DK 1622
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:49:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13803
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..816
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 299.8; E-value: 2.5e-91)"
                     /gene_kind="other"
                     /locus_tag="MXAN_3639"
                     /note="identified by similarity to SP:Q56646; match to
                     protein family HMM PF04954; match to protein family HMM
                     PF08021"
                     /product="iron-chelator utilization protein"
                     /protein_id="ABF89135.1"
                     /transl_table=11
                     /translation="MTTTTERVYRRGPFPVKFRLLEVKRVTRVTPQMVRITLAGEDLEG
                     FYSPGADDHVKLLFPEEGKRMPVIPTVTPTGLVLKEGERKPDARDYTPRRYDAAAGELD
                     IDFVVHGTGPATTWASKAQVGDLLAVGGPRGSTFVAQDFSWYLLAGDQSALPAIGRILE
                     ELPEGTRAIVFCEVPDASEEQHFTTRANATVTWLHRNGVEAGHSDVLQQAIRGLEFPAG
                     DYFAWVAGEAHTVRPIKDHLINERGANKSWVRVTGYWKRGTSDHHDAKG"
     protocluster    1..13803
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4717:13803]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4718..13803
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
     protocluster    1..13803
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4717:9082]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4718..9082
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..13803
                     /SMILES="NC(CCCCN)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..13803
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002492"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13803
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..816
                     /locus_tag="MXAN_3639"
     gene            complement(813..2087)
                     /locus_tag="MXAN_3640"
     CDS             complement(813..2087)
                     /NRPS_PKS="Domain: Aminotran_3 (57-343). E-value: 4.9e-26.
                     Score: 83.4. Matches aSDomain:
                     nrpspksdomains_MXAN_3640_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 223.5;
                     E-value: 7.5e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MXAN_3640"
                     /note="assignment partially based on genome context in
                     siderophore gene cluster; identified by similarity to
                     GB:AAG31135.1; match to protein family HMM PF00202"
                     /product="siderophore biosynthesis aminotransferase"
                     /protein_id="ABF91436.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.6e-26, bitscore:
                     80.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTPVKKHPSLPRPIQGELKLDRSNQLLAEARRLVPGVTQSMMKR
                     PEMFALGAFPVFLAKGKGALVEDVDGQEYIDFIGGLGANMLGHNDPAVVNAIREHLEEG
                     VLHSLPTPVEVSAAQTLVDLIPGAEMARFFKTGADATSAAVRLARHITGKQKIITVGYN
                     GWHDHFMFDTPGVPAALAALTLRMPLFTPPDEPALLASIEKNASELALVLLSVPYNRPL
                     TPAFLQQVRATCTANNVLFALDEVVTGFRLAVGGAQEFFDVRADFVTLSKSIAGGMPLS
                     AIAGPAKHLSRLSELQVSTTFGGELLSLYVCDAVLKGYRDGAYIQHLAHLGRKLREGVN
                     AQAEAAGSSLRVIGYDAIPFFLFAKDPTEHAKQMQPFQAGMARRGILLRRDVTFLSTAH
                     TEEQIDYAIEMTGEVLRSLAQPAAA"
     aSDomain        complement(1059..1916)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3640_Aminotran_3.1"
                     /evalue="4.90E-26"
                     /label="MXAN_3640_Aminotran_3.1"
                     /locus_tag="MXAN_3640"
                     /protein_end="343"
                     /protein_start="57"
                     /score="83.4"
                     /tool="antismash"
                     /translation="LAKGKGALVEDVDGQEYIDFIGGLGANMLGHNDPAVVNAIREHLE
                     EGVLHSLPTPVEVSAAQTLVDLIPGAEMARFFKTGADATSAAVRLARHITGKQKIITVG
                     YNGWHDHFMFDTPGVPAALAALTLRMPLFTPPDEPALLASIEKNASELALVLLSVPYNR
                     PLTPAFLQQVRATCTANNVLFALDEVVTGFRLAVGGAQEFFDVRADFVTLSKSIAGGMP
                     LSAIAGPAKHLSRLSELQVSTTFGGELLSLYVCDAVLKGYRDGAYIQHLAHLGRKLREG
                     VNAQA"
     gene            complement(2126..3352)
                     /locus_tag="MXAN_3641"
     CDS             complement(2126..3352)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 294.7; E-value: 1.4e-89)"
                     /gene_kind="transport"
                     /locus_tag="MXAN_3641"
                     /note="identified by match to protein family HMM PF07690"
                     /product="major facilitator family transporter"
                     /protein_id="ABF91569.1"
                     /transl_table=11
                     /translation="MTASFSPRQERLLILLLAGVQFTHLLDFMIVLPLGPEFMRLFSLS
                     AAQFGTLVSSYTLASAAMGVLGLAWVDRFGRRSTLLVILGGFITATLACGAAQSHAWLL
                     VARSIAGGCAGLMGAVIMSIIADTIPGERRGQAIGTVMSSLGLSAVAGVPLSLGMANML
                     GWRAPFWAIGVLGALLWFGLLAVLPRLDAHVTTDSDRQAPSVTALFTPGFALGWLLTFS
                     VAFSSFLLIPYLSAFMVGNLGLKQTDLPWVYLAGGAATLLAARQVGRWVDRFGPARVLG
                     LLLVGTMVPHLGFTHLPAAPLPVVMVAFVLFMSLTSTRPIPTIALISAKVPPPLRGRYM
                     AMNMAASDGASGLAAWASGLMLATTPGGALVGFGLAGWLAVGVTTVSLFILWTFGRSAV
                     PLNAAPTPR"
     gene            complement(3369..4721)
                     /locus_tag="MXAN_3642"
     CDS             complement(3369..4721)
                     /EC_number="2.5.1.54"
                     /codon_start=1
                     /locus_tag="MXAN_3642"
                     /note="identified by similarity to SP:P29976; match to
                     protein family HMM PF01474; match to protein family HMM
                     TIGR01358"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="ABF85885.1"
                     /transl_table=11
                     /translation="MTNPTWTPDSWRHKPVKYMPEDYPDAQALVQTEAELSRLPPLVFA
                     DETRQLTARLARVAEGKAILLQGGDCAESFKEFTTDNIRDTYRLLLQMAMVLTFAGNRP
                     VVKVGRIAGQFAKPRSSPMETLGGVTLPSYRGDIINGMEFDAQARTPDPRRLLKAYHQS
                     SATLNLLRAFAQRGYEELAEPQRWPQGGINRLLADRILESLSFMRALGVSPEPRSGSNA
                     IDFFTSHEALLLNVEEAMTRAEPDGSGWYDSSAHMLWIGERTRQLDGGHVEFMRGIQNP
                     IGIKCGPTMEPDEVLRLMDLLNPQGIPGRITLIGRFGADLVAERLPRLMAATRRDGRPV
                     IWSIDPMHGNTHKAGNGYKTRSFDRILTEVCGFMDAAAAEGVHPGGLHLEMTGQNVTEC
                     LGGPQPVTEDDLSSRYHTHCDPRLNADQALQLAFLVAESMPSLRTHEARAA"
     gene            complement(4718..9082)
                     /locus_tag="MXAN_3643"
     CDS             complement(4718..9082)
                     /NRPS_PKS="Domain: Condensation_Starter (16-307). E-value:
                     3.5e-100. Score: 327.0. Matches aSDomain:
                     nrpspksdomains_MXAN_3643_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-868). E-value: 1.9e-94.
                     Score: 308.4. Matches aSDomain:
                     nrpspksdomains_MXAN_3643_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (975-1044). E-value: 9.7e-22. Score:
                     68.9. Matches aSDomain: nrpspksdomains_MXAN_3643_PCP.1"
                     /NRPS_PKS="Domain: TD (1084-1322). E-value: 3e-80. Score:
                     260.8. Matches aSDomain: nrpspksdomains_MXAN_3643_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 103;
                     E-value: 3.5e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MXAN_3643"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF00668; match to protein family HMM PF01073;
                     match to protein family HMM PF01370; match to protein
                     family HMM PF07993; match to protein family HMM TIGR01733;
                     match to protein family HMM TIGR01746"
                     /product="non-ribosomal peptide synthase MxcG"
                     /protein_id="ABF87167.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-44, bitscore:
                     141.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-100, bitscore:
                     324.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-14, bitscore:
                     43.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-08,
                     bitscore: 23.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.1e-66, bitscore:
                     213.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTRESLAMGETHEAGWPLSAAQHGIWVGQQFDLTSAIYNAGECI
                     EIRGPLVVEHFESALRQAIDEAEALHARFVPGASGPVQFVQPRASWQLHVADVSHTPDP
                     WAAAQIWMHEDLTRTVDLGQGPLFAEALFKAAPDRYFWFQRAHHIALDGFGFSLVARRV
                     ADLYTARVTGKPATNGFGSLRAVIDEDAAYQGGVQHAADHAFWVERFTHGPTPVTLAEP
                     APMTPRFVRQTRHLSPADLERMQAAAKQAGLTWPDLVLAATAAWLHQHTGAPEIVLGLP
                     VMARLGSAAIRVPCMAMNIVPLRVPVRPDAGLFAMARDVAAELRAMRPHLRYRYEQLRR
                     DLKRVGGQRRLFGPVVNIMPFDYALRFAGMPAFAHNLSAGPVEDLSIGMYARSDGSGLR
                     VDFDANPACYSPDVLDAHQLGFLQLLESLVASPEQPVRAAPAPARPSVVDGGPLPIPQR
                     PVLELFKEQARARPDAIAVEHGEHHLTYAALLQSAQALAERLRADGARPDTLVAVSLPR
                     SIDAIVATLGVLFSGAGYLPVDPFGPESRTKAILDDAAPRLTVSSAVKDLTAGMPPQTP
                     GQLAVHRRADPELPTTATQPGAPLAYVIYTSGSTGQPNGVQIDHDALAHFVAGATFRYE
                     VTPEDRVLQFAPLHFDASVEEIFVSLCAGATLVLRTDEMLQSVPRLLEACATHGITLLD
                     LPTAFWHELAYSMSTGAARLPPSLRTVIIGGEAALPERVARWRASAGPKVRLLNTYGPT
                     EATVVATVATLSGGPDVTPAGEDVPIGRPLPGVRAAIADAKGRIVPTGEEGELHLLGGA
                     LARGYLGREALTATRFITLDALPGSPRAYRTGDKARLREDGQLVFVGRVDDEFKISGHR
                     IDPSEVETALLGHPGVREAAVVGQVLPSGSRRLCAHVVTTQPAPTVAELRQHLLNGLPA
                     PMVPGTFVFTERLPRTSTGKLDRAELRRLLPTEEAATTTAGTTALERVVLKVWEEVLGV
                     TTTSAQDDFFDLGGQSLQSIQVANRLSIELGREIPVATVFRYPTAAGLAQALEQGTDGA
                     SDAGGLTESMLADAVLSEDVVPKLTVASAESPRLRQVVLTGATGFVGAHLLHQLLRQTD
                     ARVVCLVRARDEAHALERIQAALASQQLSPEHLTERVVALPSDLTQPWLGLSQARFHGL
                     ASECDTVIHNAAVVSVVREYGSLQAVNVRGTRELLRLAAAVRAKPFHYVSTLAVAPQTD
                     LSPDVPEAFVPAHPGLRDGYQQSKWIAERLVEQAGARGLPVAVYRLGRVVGAPDSAIVN
                     PQDLVWRILLAGIPVGALPQLDVAEVWTPVDYVAGAIVRMARDARPPTVFNLCPTPEVK
                     LRELFAWVRDYGYLVEHCPVGEWRNRVAERAGTGENQSTLAFFDLRSGTDVPAFGLGPI
                     RCERVHQALEGTGITCPPTDRALLYRYLDYCIARGLLPPVPATRLPTETALP"
     aSDomain        complement(5117..5830)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3643_TD.1"
                     /evalue="3.00E-80"
                     /label="MXAN_3643_TD.1"
                     /locus_tag="MXAN_3643"
                     /protein_end="1322"
                     /protein_start="1084"
                     /score="260.8"
                     /tool="antismash"
                     /translation="VVLTGATGFVGAHLLHQLLRQTDARVVCLVRARDEAHALERIQAA
                     LASQQLSPEHLTERVVALPSDLTQPWLGLSQARFHGLASECDTVIHNAAVVSVVREYGS
                     LQAVNVRGTRELLRLAAAVRAKPFHYVSTLAVAPQTDLSPDVPEAFVPAHPGLRDGYQQ
                     SKWIAERLVEQAGARGLPVAVYRLGRVVGAPDSAIVNPQDLVWRILLAGIPVGALPQLD
                     VAEVWTPVDYVAGAIV"
     aSModule        complement(5117..9034)
                     /complete
                     /domains="nrpspksdomains_MXAN_3643_Condensation_Starter.1"
                     /domains="nrpspksdomains_MXAN_3643_AMP-binding.1"
                     /domains="nrpspksdomains_MXAN_3643_PCP.1"
                     /domains="nrpspksdomains_MXAN_3643_TD.1"
                     /final_module
                     /locus_tags="MXAN_3643"
                     /monomer_pairings="Lys -> Lys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(5951..6157)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3643_PCP.1"
                     /evalue="9.70E-22"
                     /label="MXAN_3643_PCP.1"
                     /locus_tag="MXAN_3643"
                     /protein_end="1044"
                     /protein_start="975"
                     /score="68.9"
                     /tool="antismash"
                     /translation="ERVVLKVWEEVLGVTTTSAQDDFFDLGGQSLQSIQVANRLSIELG
                     REIPVATVFRYPTAAGLAQALEQG"
     CDS_motif       complement(6449..6514)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0009"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="MXAN_3643"
                     /protein_end="878"
                     /protein_start="856"
                     /score="23.2"
                     /tool="antismash"
                     /translation="FVGRVDDEFKISGHRIDPSEVE"
     aSDomain        complement(6479..7693)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3643_AMP-binding.1"
                     /evalue="1.90E-94"
                     /label="MXAN_3643_AMP-binding.1"
                     /locus_tag="MXAN_3643"
                     /protein_end="868"
                     /protein_start="463"
                     /score="308.4"
                     /specificity="substrate consensus: Lys"
                     /tool="antismash"
                     /translation="FKEQARARPDAIAVEHGEHHLTYAALLQSAQALAERLRADGARPD
                     TLVAVSLPRSIDAIVATLGVLFSGAGYLPVDPFGPESRTKAILDDAAPRLTVSSAVKDL
                     TAGMPPQTPGQLAVHRRADPELPTTATQPGAPLAYVIYTSGSTGQPNGVQIDHDALAHF
                     VAGATFRYEVTPEDRVLQFAPLHFDASVEEIFVSLCAGATLVLRTDEMLQSVPRLLEAC
                     ATHGITLLDLPTAFWHELAYSMSTGAARLPPSLRTVIIGGEAALPERVARWRASAGPKV
                     RLLNTYGPTEATVVATVATLSGGPDVTPAGEDVPIGRPLPGVRAAIADAKGRIVPTGEE
                     GELHLLGGALARGYLGREALTATRFITLDALPGSPRAYRTGDKARLREDGQLVFVGRVD
                     DEFKIS"
     CDS_motif       complement(6599..6688)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0008"
                     /evalue="9.50E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="MXAN_3643"
                     /protein_end="828"
                     /protein_start="798"
                     /score="33.9"
                     /tool="antismash"
                     /translation="PTGEEGELHLLGGALARGYLGREALTATRF"
     CDS_motif       complement(7223..7282)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0007"
                     /evalue="4.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MXAN_3643"
                     /protein_end="620"
                     /protein_start="600"
                     /score="28.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPNGVQIDH"
     CDS_motif       complement(8009..8122)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0006"
                     /evalue="8.30E-18"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="MXAN_3643"
                     /protein_end="358"
                     /protein_start="320"
                     /score="56.8"
                     /tool="antismash"
                     /translation="AAELRAMRPHLRYRYEQLRRDLKRVGGQRRLFGPVVNI"
     aSDomain        complement(8162..9034)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3643_Condensation_Starter.1
                     "
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.50E-100"
                     /label="MXAN_3643_Condensation_Starter.1"
                     /locus_tag="MXAN_3643"
                     /protein_end="307"
                     /protein_start="16"
                     /score="327.0"
                     /tool="antismash"
                     /translation="WPLSAAQHGIWVGQQFDLTSAIYNAGECIEIRGPLVVEHFESALR
                     QAIDEAEALHARFVPGASGPVQFVQPRASWQLHVADVSHTPDPWAAAQIWMHEDLTRTV
                     DLGQGPLFAEALFKAAPDRYFWFQRAHHIALDGFGFSLVARRVADLYTARVTGKPATNG
                     FGSLRAVIDEDAAYQGGVQHAADHAFWVERFTHGPTPVTLAEPAPMTPRFVRQTRHLSP
                     ADLERMQAAAKQAGLTWPDLVLAATAAWLHQHTGAPEIVLGLPVMARLGSAAIRVPCMA
                     MNIVPLRVPV"
     CDS_motif       complement(8171..8260)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0005"
                     /evalue="2.70E-15"
                     /label="C5_starter_265-294"
                     /locus_tag="MXAN_3643"
                     /protein_end="304"
                     /protein_start="274"
                     /score="48.5"
                     /tool="antismash"
                     /translation="EIVLGLPVMARLGSAAIRVPCMAMNIVPLR"
     CDS_motif       complement(8555..8587)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0004"
                     /evalue="2.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="MXAN_3643"
                     /protein_end="176"
                     /protein_start="165"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="LYTARVTGKPA"
     CDS_motif       complement(8582..8647)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0003"
                     /evalue="9.40E-12"
                     /label="C3_starter_134-155"
                     /locus_tag="MXAN_3643"
                     /protein_end="167"
                     /protein_start="145"
                     /score="37.6"
                     /tool="antismash"
                     /translation="AHHIALDGFGFSLVARRVADLY"
     CDS_motif       complement(8858..8974)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0002"
                     /evalue="1.20E-16"
                     /label="C2_starter_024-063"
                     /locus_tag="MXAN_3643"
                     /protein_end="75"
                     /protein_start="36"
                     /score="53.2"
                     /tool="antismash"
                     /translation="AIYNAGECIEIRGPLVVEHFESALRQAIDEAEALHARFV"
     CDS_motif       complement(8993..9031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3643_0001"
                     /evalue="1.30E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="MXAN_3643"
                     /protein_end="30"
                     /protein_start="17"
                     /score="11.6"
                     /tool="antismash"
                     /translation="PLSAAQHGIWVGQ"
     gene            complement(9119..10018)
                     /locus_tag="MXAN_3644"
     CDS             complement(9119..10018)
                     /EC_number="3.3.2.1"
                     /NRPS_PKS="Domain: PP-binding (221-282). E-value: 4.8e-11.
                     Score: 35.0. Matches aSDomain:
                     nrpspksdomains_MXAN_3644_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 382.8; E-value:
                     1.1e-116)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MXAN_3644"
                     /note="identified by similarity to SP:P45743; match to
                     protein family HMM PF00550; match to protein family HMM
                     PF00857"
                     /product="isochorismatase"
                     /protein_id="ABF88819.1"
                     /sec_met_domain="PP-binding (E-value: 7.7e-12, bitscore:
                     35.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPAIAPYPMPGTTDLPKNKVSWTPDPSRAVLLIHDMQRYFVEA
                     FTQGQSPVTELVANIQRLRQHCTALGIPVVYSAQPGGQTPEQRGLLLDFWGGGINGGPD
                     QKRIIDALTPAEGDIQLTKWRYSAFRKTDLMDQMKKLGRDQILISGIYAHIGCLQTASD
                     AFMSDVRPFLIADALGDFSLAHHQLALSYAAQLCAVTTTTQQVLDALGPVSTSSTLTRE
                     QVRAEVAELLQESPEALGDDDNLLERGMDSIRLMTLVEKWRAAGAETTFVELAERPTLA
                     DWFTLLSLGNTPASRNAA"
     aSDomain        complement(9173..9355)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3644_PP-binding.1"
                     /evalue="4.80E-11"
                     /label="MXAN_3644_PP-binding.1"
                     /locus_tag="MXAN_3644"
                     /protein_end="282"
                     /protein_start="221"
                     /score="35.0"
                     /tool="antismash"
                     /translation="EQVRAEVAELLQESPEALGDDDNLLERGMDSIRLMTLVEKWRAAG
                     AETTFVELAERPTLAD"
     gene            complement(10031..11677)
                     /locus_tag="MXAN_3645"
     CDS             complement(10031..11677)
                     /EC_number="2.7.7.58"
                     /NRPS_PKS="Domain: AMP-binding (35-440). E-value: 1.9e-86.
                     Score: 282.0. Matches aSDomain:
                     nrpspksdomains_MXAN_3645_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     488.9; E-value: 2.4e-148)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="MXAN_3645"
                     /note="identified by similarity to SP:P40871; match to
                     protein family HMM PF00501; match to protein family HMM
                     TIGR02275"
                     /product="2,3-dihydroxybenzoate-AMP ligase"
                     /protein_id="ABF86856.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-96, bitscore:
                     312.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPALPGCPTWPEAYAARYREAGYWRSETFGQLLHERAQRHGER
                     TALVAGERRLTYANLDARVSQLAAGFHALGIQARDRVVVQLPNVAEFFEVIFALFRLGA
                     LPVFALPAHRASEIGYFCAFTEAVAYVIADKQAGFDYRTLAEQVRGTCPTLKHVIVAGD
                     AGPFTALSSLYAAPTALPPGPAPSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVDI
                     CQLDETSVYLCALPAAHNFPLSSPGVLGTFYAGGTAVLAPNSSPDTVFPIIERERVTIT
                     AVVPPLAMVWMDAAKTRRHQLASLRVLQVGGARLSTEAAMRVKPTLGCTLQQVFGMAEG
                     LVNYTRLDDPEDVIVSTQGRPISPDDEIRVVDEDGEDVAPGETGQLLTRGPYTIRGYYK
                     AEAHNAKAFTDDGFYHTGDVVRVTPQGYLVVEGRAKDQINRGGDKVAAEEVENHLLAHP
                     DVHDAAVVAVPDAFLGERTCAFVIARGTPPAPNVLTAFLRQRGLAAFKIPDRVEFVEAF
                     PKTGVGKVSKKALRDVLAGAPSPTPVSRATR"
     aSDomain        complement(10358..11572)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3645_AMP-binding.1"
                     /evalue="1.90E-86"
                     /label="MXAN_3645_AMP-binding.1"
                     /locus_tag="MXAN_3645"
                     /protein_end="440"
                     /protein_start="35"
                     /score="282.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HERAQRHGERTALVAGERRLTYANLDARVSQLAAGFHALGIQARD
                     RVVVQLPNVAEFFEVIFALFRLGALPVFALPAHRASEIGYFCAFTEAVAYVIADKQAGF
                     DYRTLAEQVRGTCPTLKHVIVAGDAGPFTALSSLYAAPTALPPGPAPSDVAFFQLSGGS
                     TGVPKLIPRTHDDYIYSLRGSVDICQLDETSVYLCALPAAHNFPLSSPGVLGTFYAGGT
                     AVLAPNSSPDTVFPIIERERVTITAVVPPLAMVWMDAAKTRRHQLASLRVLQVGGARLS
                     TEAAMRVKPTLGCTLQQVFGMAEGLVNYTRLDDPEDVIVSTQGRPISPDDEIRVVDEDG
                     EDVAPGETGQLLTRGPYTIRGYYKAEAHNAKAFTDDGFYHTGDVVRVTPQGYLVVEGRA
                     KDQINR"
     gene            complement(11674..12918)
                     /locus_tag="MXAN_3646"
     CDS             complement(11674..12918)
                     /EC_number="5.4.4.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 400.3; E-value:
                     2.2e-121)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MXAN_3646"
                     /note="identified by similarity to SP:P45744; match to
                     protein family HMM PF00425; match to protein family HMM
                     TIGR00543"
                     /product="isochorismate synthase"
                     /protein_id="ABF92111.1"
                     /sec_met_domain="EntC (E-value: 2.9e-152, bitscore: 496.7,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAEPKEQEHPMGPQTLAAQLLESYEAGSSFFFATPRRTLLARG
                     TFATVPHQGGADALARLPVRVTAVLNDARQADHDIPVAVGAVPFDGSVPAQLVVPLTLQ
                     RAGPLVFDKDVPVQRPFSASYTVQPVPEPAAYLNGVAQALKLMQSGPLQKVVLSRSLHL
                     NAAAPIDLRQLLRNLAQRNPSGYTFAADLPQQDGTRGAGLRTLIGASPELLVSRSGFQV
                     VANPLAGSAARSADPLEDQERAAALLKSPKDLHEHAVVIDAVAEALRPYCKTLNVPAGP
                     SLVNTATMWHLSSRITGELADPSISSLTLAAAMHPTPAVCGYPTRLAHEAIGSIEPFER
                     GYYTGTVGWCDATGDGQWAVTIRCAEASERTLRIFAGAGIVVGSTPESELAETEAKFRT
                     MLHAMGLGHGAGVQS"
     gene            complement(13030..13803)
                     /locus_tag="MXAN_3647"
     CDS             complement(13030..13803)
                     /EC_number="1.3.1.28"
                     /NRPS_PKS="Domain: PKS_KR (6-163). E-value: 4.4e-13. Score:
                     41.4. Matches aSDomain: nrpspksdomains_MXAN_3647_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     237.9; E-value: 1.9e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="MXAN_3647"
                     /note="identified by similarity to SP:P39071; match to
                     protein family HMM PF00106"
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="ABF88980.1"
                     /sec_met_domain="EntA (E-value: 4.6e-115, bitscore: 372.8,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.7e-35, bitscore:
                     109.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTPTRVALVTGAAQGIGAAVARALAGEALIAAVDTNADGLSALV
                     AELRQKHQHAVAYPASVSDVAAVDAVVERIERELGPIEVLANVAGVLRTGPILSYSDED
                     WAFTFSVNTLGVFQVSRAVARRMVPRRSGVIVTVGSNAAAVPRTQMAAYAASKAASSMF
                     TKCLGLELAPHGIRCNVVSPGSTDTAMQRALWADDSGAQAVIAGSPEAYRLGIPLQRIA
                     TPEDIANAVRFLVSDAARHITLHDLRVDGGATLDA"
     aSDomain        complement(13315..13785)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MXAN_3647_PKS_KR.1"
                     /evalue="4.40E-13"
                     /label="MXAN_3647_PKS_KR.1"
                     /locus_tag="MXAN_3647"
                     /protein_end="163"
                     /protein_start="6"
                     /score="41.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGAAQGIGAAVARALAGEALIAAVDTNADGLSALVAELRQK
                     HQHAVAYPASVSDVAAVDAVVERIERELGPIEVLANVAGVLRTGPILSYSDEDWAFTFS
                     VNTLGVFQVSRAVARRMVPRRSGVIVTVGSNAAAVPRTQMAAYAASKAASSMF"
     CDS_motif       complement(13390..13443)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3647_0002"
                     /evalue="4.10E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="MXAN_3647"
                     /protein_end="138"
                     /protein_start="120"
                     /score="0.2"
                     /tool="antismash"
                     /translation="RAVARRMVPRRSGVIVTV"
     CDS_motif       complement(13726..13779)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MXAN_3647_0001"
                     /evalue="6.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="MXAN_3647"
                     /protein_end="26"
                     /protein_start="8"
                     /score="12.4"
                     /tool="antismash"
                     /translation="LVTGAAQGIGAAVARALA"
ORIGIN
        1 gtgacgacga cgactgagcg tgtctatcgg cggggaccgt tccccgtgaa gttccgcctc
       61 ttggaggtga agcgggtgac gcgggtgacg ccgcagatgg tccgcatcac ccttgcgggc
      121 gaggacctgg agggcttcta cagccccggc gcggacgacc acgtgaagct gctgttcccg
      181 gaggagggca agcgcatgcc tgtcatcccc acggtgacgc ccacggggtt ggtgctgaag
      241 gaaggcgagc gcaagccgga cgcgcgtgac tacacgccgc gccgctatga cgccgcggca
      301 ggcgagctgg acatcgactt cgtggtgcac ggcacggggc ccgcgacgac gtgggcgagc
      361 aaggcgcagg tgggtgacct gctggccgtg ggtgggccgc gcggctccac gttcgtggcg
      421 caggatttca gttggtacct gctcgcgggc gatcagtcag cgctgccggc cattggccgc
      481 atcctggagg agctgccgga ggggacgcgc gccatcgtgt tctgcgaagt cccggacgcg
      541 tccgaggagc agcacttcac cacccgcgcc aacgcgacag tgacgtggct gcaccgcaac
      601 ggcgtggagg cggggcactc ggacgtgttg cagcaggcca tccgcgggct ggagttcccc
      661 gcgggggact acttcgcctg ggtggcgggt gaggcgcaca ccgtgcgccc catcaaggac
      721 cacctcatca acgagcgtgg cgccaacaag agctgggtcc gggtgacggg ctattggaag
      781 cgcggcacct cggaccacca cgacgcgaag ggctaggccg ccgccggctg cgcgagggag
      841 cggaggactt cgcccgtcat ctcgatggcg tagtcaatct gctcctccgt gtgcgccgtg
      901 ctgaggaagg tgacgtcgcg gcgcagcagg atgccccggc gggccatgcc cgcctggaag
      961 ggctgcatct gcttcgcgtg ctccgtcggg tccttggcga acaggaagaa gggaatcgcg
     1021 tcgtagccaa tcacgcgcaa cgatgagccc gcggcctccg cctgggcgtt gacgccctcg
     1081 cgcagcttgc ggcccaggtg ggccaggtgc tggatgtagg cgccatcccg gtagcccttc
     1141 agcaccgcgt cgcacacgta cagcgacagc agctcaccgc cgaaggtggt ggacacctgg
     1201 agctcgctca ggcggctcag gtgcttcgcc ggaccggcga tggccgacag cggcatgccg
     1261 ccagcgatgc tcttggacag cgtgacgaag tccgcgcgga cgtcgaagaa ctcctgggcg
     1321 ccgcccacgg cgagccggaa gccggtgacg acttcgtcca gggcgaacag gacgttgttc
     1381 gcggtgcacg tggcgcgcac ctgttgcagg aaggccgggg tgaggggccg gttgtagggc
     1441 accgacaaca gcaccagggc gagctcgctg gcgttcttct cgatgctggc cagcagggcc
     1501 ggttcgtccg ggggcgtgaa gagcggcatc cgaagggtca gcgccgccag cgcggccggg
     1561 acgcccggcg tgtcgaacat gaagtggtcg tgccagccgt tgtagccgac ggtgatgatc
     1621 ttctgcttgc cggtgatgtg gcgcgccagg cgcacggcgg cggacgtggc atccgcgccc
     1681 gtcttgaaga agcgcgccat ctccgcgccg gggatgaggt ccaccagcgt ctgggcggcg
     1741 gagacctcca cgggcgtggg cagcgagtgg aggacccctt cctccaggtg ctcccggatg
     1801 gcgttcacca cggctgggtc attgtggccc agcatgttgg cgcccaggcc gccgatgaag
     1861 tcgatgtact cctggccgtc cacgtcctcc accagcgcgc ccttgccctt ggccaggaac
     1921 acggggaagg cgccgagcgc gaacatctcc gggcgcttca tcatggactg cgtgacgccg
     1981 gggaccagcc gccgcgcctc ggcgaggagc tggttggagc ggtcgagctt cagctcgccc
     2041 tggatgggac gaggcaggga agggtgcttc ttgacgggag tgtccatgga cgtttccttc
     2101 tgtgggtcga gacggagact gcgattcacc gaggcgtggg cgccgcgttg agcgggacgg
     2161 cgctacggcc aaaggtccag aggatgaaga gcgaaacggt ggtgacgccc acggcgagcc
     2221 atccggccag cccgaagccc accagcgcac cgccaggcgt ggtggccagc atcaggccgc
     2281 tggcccacgc cgcgagcccg gaggcaccgt cgctggcggc catgttcatg gccatgtacc
     2341 gcccgcgcag cggcggcggc accttcgcgg agatcaacgc gatggtgggg atgggccgcg
     2401 tggacgtcag ggacatgaag aggacgaagg cgaccatcac caccggcagc ggagcggcgg
     2461 gaaggtgcgt gaagcccagg tgcggcacca tagtgcccac cagcagcagc ccgagcaccc
     2521 gggcggggcc aaaccggtcc acccagcggc ccacctgacg cgccgcgagc agcgtggcgg
     2581 cgccgccagc caggtacacc cagggcaggt cggtctgctt cagtccgagg tttccgacca
     2641 tgaacgcgct caggtacgga atcagcaaga agctggagaa ggcgacgctg aacgtcagca
     2701 gccagcccag cgcgaagccc ggcgtgaaga gcgccgtgac ggaaggcgcc tgacgatccg
     2761 agtccgtggt gacatgcgca tccagtcgcg gaagcacggc gagcagcccg aaccacagga
     2821 gcgccccaag gacgccaatg gcccagaagg gcgcgcgcca gccgagcatg ttggccatgc
     2881 ccaggctcag gggaacaccc gccaccgcag acaacccgag cgatgacatc accgtgccaa
     2941 tggcctggcc ccggcgttca ccggggatgg tgtccgcgat gatggacatg atgaccgcgc
     3001 ccatgaggcc cgcacatcct cccgcgatgc ttcgggccac cagcagccac gcgtggctct
     3061 gcgccgcgcc gcaggccagc gtggctgtga tgaaccctcc caggatgacc agcaacgtgc
     3121 ttctgcggcc aaacctgtcg acccacgcga gccccagcac gcccatggcg gcggaggcca
     3181 acgtgtagga ggacaccaac gttccgaact gcgcggctga cagactgaac agccgcatga
     3241 actccggccc cagcggcagg acgatcatga agtccagcaa gtgggtgaac tgcacgcccg
     3301 ccagcagcag gatgagcaga cgctcctgtc gcggtgagaa cgaggcggtc acgaaaggct
     3361 cctgcgattc aggccgcacg ggcttcgtgc gtgcgaaggg acggcatgga ttcggcgacg
     3421 aggaaggcca actgaagggc ctggtccgcg ttgaggcgcg gatcgcagtg ggtgtggtag
     3481 cggctggaga ggtcgtcttc cgtcacgggc tgtgggccgc ccaggcattc ggtgacgttc
     3541 tgccccgtca tctccaggtg caggcccccg gggtggacgc cttccgcggc ggccgcgtcc
     3601 atgaagccac acacctccgt gaggatgcgg tcgaaggagc gcgtcttgta gccattgccg
     3661 gccttgtggg tgttgccgtg catcgggtcg atggaccaga tgaccgggcg cccgtcccgg
     3721 cgggtggcgg ccatgagccg gggcagccgt tccgcgacca ggtccgcgcc aaaccgcccg
     3781 atgagggtga tgcggcccgg gatgccctgg ggattgagga ggtccatcag ccggagcact
     3841 tcgtcgggct ccatggtggg gccacacttg atgccaatgg ggttctggat gccgcgcatg
     3901 aactccacgt ggccgccgtc gagctggcgg gtgcgctcgc caatccacag catgtgcgcg
     3961 gacgagtcgt accagccgct gccgtcgggc tcggcgcgcg tcatggcctc ctccacgttg
     4021 aggagcaggg cttcgtggct ggtgaagaag tcgatggcat tggagccgct gcgaggctcg
     4081 gggctgacac ccagcgcccg catgaacgac agggattcga ggatgcggtc cgccagcaag
     4141 cggttgatgc cgccctgggg ccagcgctgg ggctcggcga gctcctcgta gccgcgctgg
     4201 gcgaaggctc gcagcaggtt cagcgtggcg gaggactggt gataggcctt gagcagccgg
     4261 cgcgggtcgg gcgttcgcgc ctgggcgtcg aactccatgc cgttgatgat gtccccgcgg
     4321 tagctgggca gggtgacgcc gcccagcgtc tccatggggc tggagcgcgg cttggcgaac
     4381 tgcccggcga tgcggcccac cttcaccacc ggccggttgc cggcgaaggt cagcaccatg
     4441 gccatctgca acagcagccg gtaggtgtcc cggatgttgt cggtggtgaa ctccttgaag
     4501 ctctccgcgc agtcaccgcc ttgcagcagg atggccttgc cttcggcgac cctggcgagc
     4561 cgggcggtga gctggcgcgt ctcgtccgcg aagacgagcg gaggcaggcg ggacagctcg
     4621 gcttcggtct ggaccagggc ctgcgcgtcc ggatagtcct ccggcatgta cttgacgggc
     4681 ttgtgccgcc aggagtctgg cgtccaggtg gggttcgtca cgggagtgcc gtttcggttg
     4741 gaaggcgggt tgcgggcacg ggcggcagca ggccccgcgc aatgcagtag tcgaggtatc
     4801 ggtacagcag cgcacggtcc gtgggcgggc aggtgatgcc cgttccctcg agcgcttgat
     4861 ggacccgctc acaacggatg gggcccaggc caaacgcggg cacgtccgtg cccgagcgca
     4921 ggtcgaaaaa ggcgagcgtg gattggttct ccccggtgcc ggcgcgctcc gccacgcggt
     4981 tgcgccactc acccacgggg cagtgctcca cgaggtagcc gtagtcacgg acccaggcga
     5041 acagctcacg gagcttcacc tcgggcgtgg gacacagatt gaacaccgtg ggcgggcggg
     5101 catcgcgcgc catccggacg atggctcccg ccacgtagtc cacgggcgtc cacacctcgg
     5161 cgacgtcgag ctggggcagc gcgcccacgg gaattcccgc cagcaggatg cgccacacca
     5221 ggtcctgcgg attgacgatg gcgctgtcgg gcgcacccac cacgcggccc agtcgataca
     5281 cggccacggg gagtccgcgc gctccggcct gctcgacgag ccgctcggcg atccacttgc
     5341 tctgctggta gccgtcgcgc aggcccgggt gcgcgggcac gaaggcctcc ggcacgtcgg
     5401 ggctgaggtc ggtctgcggc gccacggcca gggtggagac gtagtggaag ggcttggcgc
     5461 ggaccgcggc ggccaggcgc agcagctcgc gggtgccgcg cacattcacg gcctggaggc
     5521 tgccgtattc gcgcaccacg ctgaccacgg cggcgttgtg gatgacggtg tcacactccg
     5581 aggccagccc gtggaagcgc gcctggctca ggcccagcca gggctgggtg aggtccgagg
     5641 gcagcgccac cacgcgctcc gtcaggtgtt cgggggagag ctgctgggac gccagcgcgg
     5701 cctggatgcg ctccagggcg tgcgcctcgt cgcgagcgcg gaccaggcac accacgcgcg
     5761 cgtccgtctg gcgcaggagc tggtggagca ggtgcgcccc gacgaagccg gtggctccgg
     5821 tgaggacgac ctgacgcagc cgcggagact cggcggaagc caccgtgagc ttggggacga
     5881 cgtcctcgga cagcacggcg tcggcgagca tgctctcggt gaggcccccg gcgtcggagg
     5941 cgccgtcggt gccttgctcc agcgcctggg ccagtccggc cgccgtcggg tagcggaaga
     6001 cggtggcgac gggaatctcg cggcccagct cgatgctgag ccggttggcg acctggatgc
     6061 tctggagcga ctggccgccc aggtcgaaga agtcatcctg cgcggacgtc gtcgtcacgc
     6121 ccagtacctc ttcccagacc ttcagcacca cacgctccag ggccgtggtt cccgctgtgg
     6181 tggtcgcggc ctcttcggtg ggcagcaggc ggcgcagctc ggcgcggtcc agcttgccgg
     6241 tgctggtgcg tggcagccgc tccgtgaaca cgaacgtacc gggcaccatg ggggcaggca
     6301 ggccgttcag caggtgctgc cgtagctccg ccacggtggg cgcgggctgc gtggtgacga
     6361 cgtgcgcgca cagccggcgc gaaccgctgg ggagcacctg gccgacgacg gccgcctcgc
     6421 gcacgcccgg gtggccgagc agcgccgttt cgacctcgga cgggtcgatg cggtggccgc
     6481 tgatcttgaa ctcgtcgtcg acgcggccca cgaagacaag ttggccgtcc tcgcgcagtc
     6541 gggccttgtc acccgtgcgg taggcgcggg ggcttcccgg cagggcgtcg agcgtgatga
     6601 agcgcgttgc cgtcagcgcc tcgcggccca ggtagccccg ggcgagcgcg ccgcccagca
     6661 ggtggagctc gccttcctca cccgtgggga cgatgcggcc cttcgcgtcg gcaatcgccg
     6721 cgcgcacgcc aggcaggggg cgtccgatgg gcacgtcttc cccggcgggc gtcacgtcgg
     6781 gaccgccgct gagcgtggcg acagtggcca ccacggtggc ttcggtgggg ccgtaggtgt
     6841 tgagcagccg gaccttggga ccggcggagg cccgccagcg ggcgacgcgc tcgggcaagg
     6901 cggcctcacc gccgatgatg acggtgcgca gcgagggcgg cagccgggcc gcgcccgtgg
     6961 acatgctgta ggccagctcg tgccagaagg ccgtgggcag gtccagcagg gtgatgccat
     7021 gtgtggcgca ggcttcgagc agccggggca ccgactggag catctcgtcc gtgcgcagca
     7081 ccagtgtggc tccggcgcac agggagacga agatttcctc cacgctggca tcgaagtgca
     7141 gtggcgcgaa ctgcagcacc ctgtcttcgg gcgtcacctc gtagcggaac gtcgcgcccg
     7201 ccacgaagtg ggccagtgcg tcgtggtcaa tctgcacgcc gttgggctgg ccggtggagc
     7261 cggacgtgta gatgacgtac gccagcggcg cgcccggctg ggtcgccgtg gtcggcagct
     7321 ccgggtcggc gcgccggtgc accgcgagct gcccgggtgt ctgcggaggc atgccggccg
     7381 tgaggtcctt cacggcgctg ctcaccgtca gtcgtggcgc ggcgtcatcc aggatggcct
     7441 tcgtccggga ttcggggccg aacgggtcca cggggaggta tcccgcgccg gagaagagga
     7501 cacccagcgt ggccacgatg gcgtcgatgc ttcggggcag tgagacggcc accagcgtgt
     7561 cgggccgcgc gccgtcggcc ctcagccgct ccgcgagcgc ctgtgcggac tggagcagcg
     7621 ccgcataggt gaggtggtgc tcgccatgct ccacggcgat ggcatccggc cgcgcacggg
     7681 cctgctcctt gaagagctcc agcacgggcc gttgcggaat cggcaggggc ccgccatcca
     7741 cgacggaggg ccgcgcgggg gcaggtgccg cgcgcacggg ctgctcgggc gaggccacca
     7801 gtgactccaa caactggagg aagccgagct ggtgggcgtc caggacgtcg gggctgtagc
     7861 aggcggggtt cgcgtcgaag tccacgcgca gtccgctgcc atcggagcgg gcgtacatgc
     7921 cgatggacag gtcctcgacg ggacccgcgg agaggttgtg ggcgaaggcc ggcatccccg
     7981 cgaagcgcag ggcgtagtcg aacggcatga tgttgaccac ggggccgaac agccgccgct
     8041 ggccgcccac gcgcttcaag tcgcggcgaa gctgctcgta gcggtagcgc aggtgcggcc
     8101 tcatggcgcg cagctctgcc gccacgtcac gggccatggc gaacaagccg gcgtccggac
     8161 gcaccgggac gcgcagcgga acgatgttca tggccatgca cggcacgcgg atggcggccg
     8221 agcccaggcg ggccatcacc ggcagaccca gcacgatttc gggcgcaccg gtgtgctggt
     8281 gcagccaggc cgccgtcgcc gcgagcacca ggtccggcca cgtgagcccg gcctgcttcg
     8341 cggcggcctg catccgctcc aggtccgcgg gcgacaggtg ccgcgtctgg cgcacgaatc
     8401 gcggcgtcat gggcgcgggc tccgcgagcg tcaccggcgt ggggccatgg gtgaagcgct
     8461 ccacccagaa ggcgtggtcc gcggcgtgct gcacgccccc ctggtaggcg gcgtcctcat
     8521 cgatgacggc gcggagggag ccgaacccgt tcgtggcggg cttgcccgtc acccgggccg
     8581 tgtagaggtc cgccacgcgg cgggccacca gcgagaagcc gaagccgtcc agggcgatgt
     8641 ggtgggcccg ctggaaccag aagtaacggt ccggcgccgc cttgaacagc gcctcagcga
     8701 acagcgggcc ctggcccagg tccaccgtgc gcgtcaggtc ctcgtgcatc cagatctggg
     8761 ccgcggccca ggggtcgggc gtgtggctga cgtcggcgac gtgtagctgc cacgacgcgc
     8821 ggggctgcac gaactgcacg gggccggagg cgccggggac gaagcgcgcg tggagcgcct
     8881 ccgcctcgtc gatggcctga cgcaaggcag actcgaagtg ctccacgacg agcggcccgc
     8941 ggatttcgat gcactcaccc gcgttgtaga tggcgctcgt gaggtcgaac tgctggccga
     9001 cccagattcc atgctgggcc gcggacagcg gccaacctgc ttcgtgtgtt tcgcccatcg
     9061 ccagggactc ccgtgtgttc atgcgtcagg ggcgcgaggt gactcgcgca cggcggagct
     9121 acgcggcgtt ccgggaagcg ggcgtgttgc ccagggagag cagcgtgaac cagtcggcga
     9181 gcgtcggccg ttcggccagc tccacgaagg tggtctccgc gccagcggcc cgccacttct
     9241 ccaccagcgt catcagccgg atggagtcca ttccgcgctc gagcaggttg tcgtcgtcac
     9301 ccagcgcctc cggcgactcc tggagcagct ccgccacctc tgcgcgcacc tgctcgcggg
     9361 tgagtgtgct ggacgtggag acggggccca gcgcgtcgag cacctgctgc gtggtggtgg
     9421 tgacggcgca cagctgggct gcgtagctca acgcgagctg gtggtgcgcc agggagaagt
     9481 cacccagcgc gtcggcgatg aggaagggcc gcacgtcgct catgaaggcg tcgctggccg
     9541 tctgcaggca gccgatgtgc gcgtagatac cggagatgag gatctgatcg cggcccagct
     9601 tcttcatctg gtccatcagg tccgtcttgc ggaacgcgct gtagcgccac ttggtgagct
     9661 ggatgtcgcc ttcggcgggc gtcagcgcgt cgatgatgcg cttctggtcc ggtccgccgt
     9721 tgatgccgcc gccccagaag tccagcagca ggccgcgctg ctcgggcgtc tggccacccg
     9781 gttgggccga gtacacgacg gggatgccca gcgccgtgca gtgctgccgc agccgctgga
     9841 tgttggcgac cagctccgtc acgggcgact ggccctgcgt gaaggcctcc acgaagtagc
     9901 gctgcatgtc gtggatgagc agtacggcgc ggctcgggtc cggcgtccag gagaccttgt
     9961 tcttcggcag gtcggtggtg ccgggcatgg gatagggagc gatggcgggg agcgccatgg
    10021 ggagttcctt tcagcgcgtc gcgcgcgaaa ccggagtggg ggagggagcg ccggcgagca
    10081 cgtcgcgcag cgccttcttg ctgaccttgc cgacgcccgt cttggggaac gcctcgacga
    10141 actcgacccg gtcgggaatc ttgaaggcgg ccagaccacg ctggcgcagg aaggccgtga
    10201 gcacattggg cgctggcggc gtgccgcgcg cgatgacgaa ggcgcaggtg cgctcgccga
    10261 ggaacgcgtc cggaacggcg accaccgcgg cgtcgtgcac gtcggggtgg gccagcagat
    10321 ggttttccac ctcctcggcc gcgaccttgt cgccgccccg gttgatctga tccttggcgc
    10381 ggccctccac caccaggtag ccctggggcg tcacgcggac cacgtcaccg gtgtggtaga
    10441 agccgtcgtc ggtgaaggcc ttcgcgttgt gggcctccgc cttgtagtag ccgcggatgg
    10501 tgtacggccc gcgcgtcagc aactggcccg tctcgcccgg cgctacgtct tcgccgtcct
    10561 cgtccaccac ccggatttcg tcgtccgggg agatgggccg gccctgggtg ctgacgatga
    10621 cgtcctcggg gtcatccagg cgcgtgtagt tgaccaggcc ctcggccatg ccgaacacct
    10681 gctggagcgt gcagcccagc gtgggcttca cccgcatggc cgcctcggtg ctgaggcgcg
    10741 cgccaccgac ctggagcacc cgcaggctgg cgagctggtg ccggcgcgtc ttggccgcgt
    10801 ccatccagac catggccagt ggtggcacca ccgcggtgat ggtgacgcgc tcacgctcga
    10861 tgatcgggaa caccgtgtcc gggctggagt tgggcgccag caccgccgtg ccgcccgcgt
    10921 agaaggtgcc cagcacgccc ggcgagctga gcggaaagtt gtgcgccgcg ggcagcgcgc
    10981 acaggtacac gctcgtctcg tcgagctggc agatgtccac gctgccgcgc aggctgtaga
    11041 tgtagtcgtc gtgcgtgcgc gggatgagct tgggcacgcc cgtgcttccg ccggagagct
    11101 ggaagaaggc cacgtcgctg ggcgcgggcc ctggcggcag cgccgtgggc gcggcgtaca
    11161 ggctgctcag tgccgtgaag gggcctgcgt caccggcgac gatgacgtgt ttcagcgtcg
    11221 ggcaggtgcc gcgcacctgc tcagccaggg tgcggtagtc gaagccggcc tgcttgtccg
    11281 cgatgacgta ggccaccgcc tccgtgaagg cgcagaagta gccaatctcc gaagcgcggt
    11341 gcgcgggaag cgcgaacacc ggcagcgcgc ccagtcggaa gagggcgaag atgacctcga
    11401 agaactcggc cacgttgggc agctgcacca ccacccggtc ccgagcctgg atgcccaggg
    11461 catggaagcc ggcggccagc tggctgacgc gggcgtccag gttggcgtag gtgaggcgac
    11521 gctctccggc caccagtgcg gtccgctcgc cgtgacgctg ggcgcgttcg tggaggagct
    11581 ggccgaacgt ttcactgcgc cagtagccag cctcgcggta gcgggcggcg taggcctccg
    11641 gccaggtggg gcagccaggg agggcggggg acgtcatgac tgcaccccgg caccgtggcc
    11701 caggcccatg gcgtggagca tggtgcggaa cttggcctcg gtctccgcca gctcggactc
    11761 gggcgtggag cccaccacga tgcccgcgcc cgcgaagatg cgcagggtgc gctcactggc
    11821 ctccgcgcaa cggatggtca ccgcccactg cccatcaccc gtggcgtcgc accagcccac
    11881 cgtgccggtg tagtagccgc gctcgaaggg ctcgatggag ccaatcgcct cgtgcgccag
    11941 ccgtgtagga tagccgcaca ccgccggcgt cgggtgcatg gccgccgcca gcgtcagcga
    12001 ggagatggag gggtcggcca gctcaccggt gatgcggctg gacaggtgcc acatggtggc
    12061 ggtgttcacg agcgacggac cggcgggcac gttcagcgtc ttgcagtacg gccgcagcgc
    12121 ctccgcgacg gcgtcgatga ccaccgcgtg ctcgtgcagg tccttgggcg acttcagcag
    12181 cgcggcggcg cgctcctggt cctccagcgg atccgcgctg cgggccgcgg agccggccag
    12241 gggattggcg accacctgga acccggagcg ggacacgagc agctcggggc tggcgccaat
    12301 gagcgtgcga agtcccgcgc cgcgggtccc atcctgctgg gggaggtcgg cggcgaaggt
    12361 gtagcccgac gggttgcgct gcgcgaggtt gcgcagcagc tgccgcaggt cgatgggggc
    12421 ggcggcgttg aggtgcagcg aacgtgacag caccaccttc tggagcggcc cgctctgcat
    12481 cagcttcagg gcctgcgcga cgccgttcag gtacgcggcg ggctccggca ccggctggac
    12541 ggtgtagctg gcgctgaacg gccgctgcac cgggacgtcc ttgtcgaaca ccagcggccc
    12601 ggcgcgctgg agcgtcagcg gcaccacgag ctgtgcgggt accgagccgt cgaagggcac
    12661 cgcgcccacc gccacgggga tgtcgtggtc ggcctggcgc gcgtcattca gcaccgccgt
    12721 cacgcgcacg gggagccgcg ccagggcatc cgcgccgccc tggtgtggca cggtagcaaa
    12781 ggtgccgcgc gccagcagcg tgcggcgcgg cgtggcgaag aagaacgaag agccagcctc
    12841 gtagctctcg agcaactgcg cggcgagtgt ctgcggtccc atggggtgtt cctgttcctt
    12901 cggctcagcg ggcgtcatgc acagggcgcc acatggcggc gcctcggtgg tagttggtga
    12961 attggatcct agtaatcatt atcaactccg tggcggacga gggcctgggc gggccgcacg
    13021 agggtggggt caggcgtcga gtgtcgcgcc cccgtcgacg cggaggtcgt gcagggtgat
    13081 gtggcgtgcc gcgtccgaga cgaggaaccg caccgcgttg gcgatgtcct cgggggtggc
    13141 gatgcgttgc agggggatgc ccaggcgata ggcctcgggc gagccggcaa tcaccgcctg
    13201 cgcgccggag tcatccgccc agagcgcgcg ctgcatggcg gtgtccgtgg agccggggga
    13261 cacgacgttg cagcggatgc cgtgcggggc cagctccagg cccaggcact tggtgaacat
    13321 gctggaggcg gccttggagg cggcgtacgc ggccatctgc gtgcggggca cggcggcggc
    13381 gttggagccc acggtgacga tgacaccgct tcggcggggc accatgcgcc gggccacggc
    13441 gcgggacacc tggaacacgc ccagcgtgtt gacggagaag gtgaacgccc agtcctcgtc
    13501 gctgtaggac aggatggggc ccgtgcgcag gacgcccgcc acgttggcca gcacctcgat
    13561 agggcccagc tcccgctcga tgcgctccac cacggcgtcg accgcggcga catcactcac
    13621 gctggccggg taggccaccg cgtgttgatg cttctgccgg agctcggcca cgagggcgct
    13681 caggccgtcc gcgttggtgt cgaccgcggc gatgagggct tcgcccgcca gcgcacgtgc
    13741 cactgccgcg ccaatacctt gtgcggcacc tgtgacgagt gccacccggg tgggcgttcc
    13801 cat
//
