LOCUS       BGC0002495             19671 bp    DNA     linear   BCT 24-JUL-2016
DEFINITION  Photorhabdus luminescens strain NC19 putative transposase TnpA
            (tnpA) gene, partial cds; and putative
            2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase PhbA (phbA),
            putative 2,3-dihydro-2,3-dihydroxybenzoate synthase PhbB (phbB),
            putative 2,3-dihydroxybenzoate-AMP-ligase PhbE (phbE), putative
            isochorismate synthase PhbC (phbC), ABC-transport protein PhuC
            (phuC), nonribosomal peptide synthetase PhbH (phbH), putative
            photobactin outer membrane receptor precursor PhuA (phuA), putative
            cytoplasmic permease PhuD (phuD), putative cytoplasmic permease PhuG
            (phuG), periplasmic binding protein PhuB (phuB), putative
            photobactin biosynthesis protein PhbG (phbG), and nonribosomal
            peptide synthetase PhbF (phbF) genes, complete cds.
ACCESSION   BGC0002495
VERSION     BGC0002495
KEYWORDS    .
SOURCE      Photorhabdus luminescens
  ORGANISM  Photorhabdus luminescens
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Photorhabdus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:50:22
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19671
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[16626:19671]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16627..19671
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..19671
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:19671]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..19671
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
     cand_cluster    1..19671
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..19671
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002495"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19671
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..759)
                     /gene="phbA"
     CDS             complement(1..759)
                     /NRPS_PKS="Domain: PKS_KR (54-161). E-value: 2e-13. Score:
                     42.5. Matches aSDomain: nrpspksdomains_phbA_PKS_KR.1"
                     /codon_start=1
                     /gene="phbA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     213.1; E-value: 7.4e-65)"
                     /gene_kind="biosynthetic"
                     /note="photobactin biosynthesis"
                     /product="putative 2,3-dihydro-2,3-dihydroxybenzoate
                     dehydrogenase PhbA"
                     /protein_id="AAK95835.1"
                     /sec_met_domain="EntA (E-value: 1.1e-110, bitscore: 358.9,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIALDFSDKIVWITGAGSGIGYQTAYRFQQAGAKVIGFDITFPE
                     GDLPFTPYLLDISDPIAVSRCCEQLLAQQPQLDVLVNGAGILRLGVAEEITFEDWQQCL
                     SVNAGGAFNLFQATILQFQRQKAGAIVTIASNAAHVPRVGMSAYCASKAALRSLCLSVG
                     LELAPYGVRCNLISPGSTDTPMQRGMWQTEASKQQVIQGFSELFKLGIPLGKIATPTEI
                     ADAVLFMASDLASHITLQDIVIDGGATLGA"
     aSDomain        complement(277..597)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbA_PKS_KR.1"
                     /evalue="2.00E-13"
                     /label="phbA_PKS_KR.1"
                     /locus_tag="phbA"
                     /protein_end="161"
                     /protein_start="54"
                     /score="42.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LDISDPIAVSRCCEQLLAQQPQLDVLVNGAGILRLGVAEEITFED
                     WQQCLSVNAGGAFNLFQATILQFQRQKAGAIVTIASNAAHVPRVGMSAYCASKAALRSL
                     CLS"
     gene            complement(761..1636)
                     /gene="phbB"
     CDS             complement(761..1636)
                     /NRPS_PKS="Domain: PP-binding (220-280). E-value: 1.4e-12.
                     Score: 39.9. Matches aSDomain:
                     nrpspksdomains_phbB_PP-binding.1"
                     /codon_start=1
                     /gene="phbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 390.5; E-value:
                     4.9e-119)"
                     /gene_kind="biosynthetic-additional"
                     /note="isochorismatase; photobactin biosynthesis"
                     /product="putative 2,3-dihydro-2,3-dihydroxybenzoate
                     synthase PhbB"
                     /protein_id="AAK95836.1"
                     /sec_met_domain="PP-binding (E-value: 3e-13, bitscore:
                     39.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIPKLNSYDLPVAEGLPTNKVNWSLDKNRAALLIHDMQNYFLNF
                     WEENSPLINQVVTNIARLIEICRENGIPVFYSAQPNQQSDEERALLNDMWGPGLNCHPE
                     LQKITDALAPQAGDIVMDKWRYSAFQRTDFEQQLKIAGRDQLIICGVYAHIGCLMTATD
                     AFMRDIQPFMVADALADFSYEEHMMALKYTAGRCGRVETTEQLLVALDVKQVQWNKTRL
                     KALLLPLLDEDSDDIGDDENLLDYGLDSVRIMSLISHWRQQGYEMDFISLMKNPTINGW
                     MTLFTERQGA"
     aSDomain        complement(797..976)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbB_PP-binding.1"
                     /evalue="1.40E-12"
                     /label="phbB_PP-binding.1"
                     /locus_tag="phbB"
                     /protein_end="280"
                     /protein_start="220"
                     /score="39.9"
                     /tool="antismash"
                     /translation="RLKALLLPLLDEDSDDIGDDENLLDYGLDSVRIMSLISHWRQQGY
                     EMDFISLMKNPTING"
     gene            complement(1623..3266)
                     /gene="phbE"
     CDS             complement(1623..3266)
                     /NRPS_PKS="Domain: AMP-binding (35-438). E-value: 1.3e-78.
                     Score: 256.2. Matches aSDomain:
                     nrpspksdomains_phbE_AMP-binding.1"
                     /codon_start=1
                     /gene="phbE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     421.4; E-value: 7e-128)"
                     /gene_kind="biosynthetic-additional"
                     /note="dihydroxybenzoic acid-activating enzyme; photobactin
                     biosynthesis"
                     /product="putative 2,3-dihydroxybenzoate-AMP-ligase PhbE"
                     /protein_id="AAK95837.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-85, bitscore:
                     276.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVEFNRWPKALEQRYRQLGYWIDLPLSDIFTRQSNNGKIALICG
                     DRQFSYAELNLLVDSLAAALQRQGVKRGQTALVQLGNEAEFYIVFFALLRLGVVPVNAI
                     YSHQRSELCAYADQINPALLIADRNHSLFSDDNFIDELRACTPSLSHVVLRGDNDSILD
                     FETLLAEGAGDFIADPTPADEVAFFQLSGGSTGTPKLIPRTHNDYYYSIRASVDICQFN
                     AETRYLCALPAAHNFPMSSPGALGAFYSGGQVILANNPSADCCFPLIQQHQVNVTALIP
                     PAVSVWFEAIALSGNRDALKSLRLLQVGGARLSESLARRIPKEMGCQLQQVFGMAEGLV
                     NYTRLDDDEQHIFTTQGCPTSQDDEVWVADNDGNPVPPGVAGRLMTQGPYTFRGYYRSP
                     QHNQQCFDSNGFYCSGDLVIMAPDGYLQVVGREKDQINRGGEKIAAEEIENLLLRHPDV
                     IYAALVAIPDPLMGEKSCAFVVLRKPIKAVVLRRYLREQGIADYKLPDRFEPVPSLPIT
                     PVGKIDKKQLRQLTKQFVQPSLVGERNEHS"
     aSDomain        complement(1953..3161)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbE_AMP-binding.1"
                     /evalue="1.30E-78"
                     /label="phbE_AMP-binding.1"
                     /locus_tag="phbE"
                     /protein_end="438"
                     /protein_start="35"
                     /score="256.2"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="NNGKIALICGDRQFSYAELNLLVDSLAAALQRQGVKRGQTALVQL
                     GNEAEFYIVFFALLRLGVVPVNAIYSHQRSELCAYADQINPALLIADRNHSLFSDDNFI
                     DELRACTPSLSHVVLRGDNDSILDFETLLAEGAGDFIADPTPADEVAFFQLSGGSTGTP
                     KLIPRTHNDYYYSIRASVDICQFNAETRYLCALPAAHNFPMSSPGALGAFYSGGQVILA
                     NNPSADCCFPLIQQHQVNVTALIPPAVSVWFEAIALSGNRDALKSLRLLQVGGARLSES
                     LARRIPKEMGCQLQQVFGMAEGLVNYTRLDDDEQHIFTTQGCPTSQDDEVWVADNDGNP
                     VPPGVAGRLMTQGPYTFRGYYRSPQHNQQCFDSNGFYCSGDLVIMAPDGYLQVVGREKD
                     QINR"
     CDS_motif       complement(2049..2138)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbE_0001"
                     /evalue="9.90E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="phbE"
                     /protein_end="406"
                     /protein_start="376"
                     /score="14.8"
                     /tool="antismash"
                     /translation="PPGVAGRLMTQGPYTFRGYYRSPQHNQQCF"
     gene            complement(3304..4242)
                     /gene="phbC"
     CDS             complement(3304..4242)
                     /codon_start=1
                     /gene="phbC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 323.3; E-value:
                     5.5e-98)"
                     /gene_kind="biosynthetic"
                     /note="photobactin biosynthesis"
                     /product="putative isochorismate synthase PhbC"
                     /protein_id="AAK95838.1"
                     /sec_met_domain="EntC (E-value: 2.3e-128, bitscore: 418.4,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKILFWWGQFHSINSKMRHFLSLNNALVPKKAVSHAYFQFNLY
                     RKKTHQWPDKAHFSQMVNTAVDAMRNHRLDKIVLSRLLDIETHQPLDSIQLLRHLNQQN
                     SWSYNFHVPLQNGALIGASPELLVRKQGNTIFSQPLAGSAKRSENQQEDYKLRQALIQS
                     VKDNYEHRLVTDMMRNVLESRCQKLHISEMPSTISTPVLWHLATDIEGELKAPQENALS
                     IACLLHPTPALCGTPYQTAKNLIEELEPFKRNLFGGIVGWCDEKGNGEWVVTIRCGEVN
                     GSRVRLFAGAGIVPDSKPESEWQKQRLSFQR"
     misc_feature    4715..4733
                     /note="ferric uptake regulator (fur) binding site; iron
                     box"
     gene            complement(4764..5603)
                     /gene="phuC"
     CDS             complement(4764..5603)
                     /codon_start=1
                     /gene="phuC"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 206.5; E-value:
                     7.6e-63)"
                     /gene_kind="transport"
                     /note="similar to FepC; photobactin transport"
                     /product="ABC-transport protein PhuC"
                     /protein_id="AAK95839.1"
                     /transl_table=11
                     /translation="MATLTLEHNNQCVLSPCRLSVEELRLGYGEHIVCDELNLRIPDGR
                     FTVIIGPNGCGKSTLLRSLCRLLRPEYGRVCLDGHDIHTIPTRALARQLGLLPQSVQAP
                     QGIKVVDLVARGRFPHQRLLRQWSHEDYEAVRQAMNATGVTELAECVVDELSGGQRQRV
                     WVAMVLAQQTPLLLLDEPTTYLDIAHQIELLELFCHLNQGSGYTLIAVLHDLNQACRYA
                     DHLIVMAGGRIVVEGAPGEIITTTLVSEVFGLDCVIIDDPVSHTPLIIPQGRRFTKG"
     gene            complement(5703..8789)
                     /gene="phbH"
     CDS             complement(5703..8789)
                     /NRPS_PKS="Domain: PCP (487-552). E-value: 3.3e-16. Score:
                     51.1. Matches aSDomain: nrpspksdomains_phbH_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (576-871). E-value:
                     3.2e-46. Score: 149.6. Matches aSDomain:
                     nrpspksdomains_phbH_Condensation_LCL.1"
                     /codon_start=1
                     /gene="phbH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     175.1; E-value: 4.8e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="photobactin synthetase"
                     /product="nonribosomal peptide synthetase PhbH"
                     /protein_id="AAK95840.1"
                     /sec_met_domain="PP-binding (E-value: 2.6e-11, bitscore:
                     33.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.4e-36, bitscore:
                     114.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAREFKRILTDDEALLLDEVFNAHADGHSSSEAQETEKDLTEFEE
                     MMWLHHQQDPNASGQFACAWSLTGNINIGRLIRALELLTKEIVGINVRYRFDDEGDLRK
                     YCDPTADSPIEIYQIQSDEEAINRLLTDQCKPIELDEHPPVKFMLFMNGKRGVILGVIV
                     HHILRDSVSWPQMFTLLSDAYNNGLKTIGFGREDLFRKAISAKWLSSESGKIGIPWLYK
                     SDTTRSVLIKEMGKISYLDDSLHHRLAGRYRTTINIDVLAPFLPAEKTAYSALATVAAL
                     FGCYIAMIGSHLDVNISVSCDPEYTHDELNSPFFYSELMSLRVCQDDRSLDKIIADIER
                     QIESGNLQMGNEVEYGHDSPHILVTWLNQSQSSLRLNDAMVELLPIPPLNAHFDISLAA
                     GNVNEGQWFFELITGSSISPHIGAFLLEGFGTFIHEQNVTIAPKLTSVFLLPPKKKHQD
                     ISDTAFIIAKQQKEHEATDKSDSHRKIANIILNEFRQALSSPEMTASDDFFDLGGHSLI
                     ATRVIGRLLSLHNIEIHINHLFSYPTALKLAEYAQCHDPIDENKDELSEEQSKEDISAV
                     APLSLAQKSLWKAYAAFDFNDIFNLPFILKFSAIINEQVLEQAFFDVLQRHSVLRSLFY
                     QEEGEVYQRVVPMKDLSDYQWFWGSYEYGSLSSEEILKKEGKYQFDLSEELPLRIKFVT
                     DNASGSSFYPCYFIMWHLMSGLVTLLMEELKHAYKYRLINETPTWQEQPLPFLQYAIRQ
                     NNEGMNQSHLDYWVNNLRGAPSGEPIFKNAASELSGQANSCEGIEFEIEKVVAQGLQSL
                     ARKNGASFFNILYASIVASLNLLGATDDLIVGTSASGRDDASFFDTVGYFTTVVIHRVR
                     FTEQMTFTDLITQVKNNINDSLPYTDIPVDLIEEALSGHTDQGKDHLFEVYIQLHAKNS
                     XSGEFHMLDGSHIAFQQIVLEKQESLLGLHFEIMEEMIAGEEMVRVLFNYRSDRYSAAQ
                     ISQISEAINGILALFAKTQDSNIPLKAILPRLSECMDTL"
     aSDomain        complement(6177..7061)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbH_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.20E-46"
                     /label="phbH_Condensation_LCL.1"
                     /locus_tag="phbH"
                     /protein_end="871"
                     /protein_start="576"
                     /score="149.6"
                     /tool="antismash"
                     /translation="APLSLAQKSLWKAYAAFDFNDIFNLPFILKFSAIINEQVLEQAFF
                     DVLQRHSVLRSLFYQEEGEVYQRVVPMKDLSDYQWFWGSYEYGSLSSEEILKKEGKYQF
                     DLSEELPLRIKFVTDNASGSSFYPCYFIMWHLMSGLVTLLMEELKHAYKYRLINETPTW
                     QEQPLPFLQYAIRQNNEGMNQSHLDYWVNNLRGAPSGEPIFKNAASELSGQANSCEGIE
                     FEIEKVVAQGLQSLARKNGASFFNILYASIVASLNLLGATDDLIVGTSASGRDDASFFD
                     TVGYFTTVVIHRVR"
     CDS_motif       complement(6198..6272)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbH_0003"
                     /evalue="2.30E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="phbH"
                     /protein_end="864"
                     /protein_start="839"
                     /score="16.9"
                     /tool="antismash"
                     /translation="DLIVGTSASGRDDASFFDTVGYFTT"
     CDS_motif       complement(6885..6995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbH_0002"
                     /evalue="3.30E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="phbH"
                     /protein_end="635"
                     /protein_start="598"
                     /score="22.6"
                     /tool="antismash"
                     /translation="FNLPFILKFSAIINEQVLEQAFFDVLQRHSVLRSLFY"
     aSDomain        complement(7134..7328)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbH_PCP.1"
                     /evalue="3.30E-16"
                     /label="phbH_PCP.1"
                     /locus_tag="phbH"
                     /protein_end="552"
                     /protein_start="487"
                     /score="51.1"
                     /tool="antismash"
                     /translation="IILNEFRQALSSPEMTASDDFFDLGGHSLIATRVIGRLLSLHNIE
                     IHINHLFSYPTALKLAEYAQ"
     CDS_motif       complement(8541..8600)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbH_0001"
                     /evalue="1.90E-01"
                     /label="C2_LCL_024-062"
                     /locus_tag="phbH"
                     /protein_end="83"
                     /protein_start="63"
                     /score="4.2"
                     /tool="antismash"
                     /translation="AWSLTGNINIGRLIRALELL"
     gene            complement(8978..11038)
                     /gene="phuA"
     CDS             complement(8978..11038)
                     /codon_start=1
                     /gene="phuA"
                     /gene_functions="transport (smcogs)
                     SMCOG1107:TonB-dependent receptor (Score: 583.3; E-value:
                     1.1e-176)"
                     /gene_kind="transport"
                     /product="putative photobactin outer membrane receptor
                     precursor PhuA"
                     /protein_id="AAK95841.1"
                     /transl_table=11
                     /translation="MMYHEKEHTEKSNFVGIFGALFFGAIALTGTDAIAAEEKNPQSAQ
                     KGNTKASSSEEDVLVVTGEKVNRSIYDSGSSVEVYNLRKMKSIPNPDVNMLLQMTPNVV
                     DNGISNALPAVRGVDGSGPSQGGMAFISGTRPRINVSIDGRSFTYNELAFGTQSLWDIE
                     SVEVFRDPQSYIQGRNAIAGAVIIKSLDPTFYWESAIKSGFANQGYQQVAAMASGPLID
                     EQLAFRLSVDRQNRDSFANLVSYDPVGDPHKIESTTVRAKLLFEPLSIPELSTKLTVNH
                     LDSRAPQNEAYNPRDTLNLRHELFRPVVERKTTSGIWDISWALSDTISLENKLIYTDLA
                     YHRLTSSKIPKADTDGKELEVEPIIRFQGFDNKLNGLVGVRYFHGKQDETINLFGGSKF
                     DDKTETASAYTVLTYTVVPEIDVTLSSRFEREHRTRKGGSESVAIDFDKTYNAFLPKID
                     VAWKPQKDQTVGIAVGRGYNAGGAGVTFGKPVISYTYDPEYVWNYSLYTRNSLLDGKLE
                     LTSNLFYNDYKDMQLPYYLSLDSTMIRNANKVETYGAEVGARWLPVEKLELNANIGLLK
                     TKIKSFAESGVQGNELPRAPGYTANLLAKYLLTEDIDVSGNVMFSDTYYSQYDNSARGK
                     IPAYWIANLQLGYNFKWGRATLFAQNLFDSDKRLLVPDNNVNSIILSASRE"
     misc_feature    11258..11276
                     /note="ferric uptake regulator (fur) binding site; iron
                     box"
     gene            complement(11677..12645)
                     /gene="phuD"
     CDS             complement(11677..12645)
                     /codon_start=1
                     /gene="phuD"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 276.1; E-value: 5.6e-84)"
                     /gene_kind="transport"
                     /note="photobactin transporter"
                     /product="putative cytoplasmic permease PhuD"
                     /protein_id="AAK95842.1"
                     /transl_table=11
                     /translation="MVICAMLLLIMVLALFSMTIGKFNITIEQIITIFWGPGSGSVSEK
                     IIMDIRLPRVLPAIFVGAALGVSGAVFQSISRNALGSPDVIGFTVGAATGAIIQIVLFD
                     NNAVQIAIAAVAGGTLTAAVVYLLSLKSGAIGGYRLILTGIGVGSVLSALNGLLLVKGN
                     LDNAVMANLWLAGSLNARTWVHVFPVLTGVVLLVPLVLFMTRKLSIIEMGDDIACQLGI
                     RVERVRLIMIFCAVVLAALATGAAGPIAFVALAAPQLVVRLTCSRNMPVISAALMGACL
                     LLSADLLTQLLPLRAAVPIGLMTGLVGGIYLIWLLTRSRQI"
     gene            complement(12737..13789)
                     /gene="phuG"
     CDS             complement(12737..13789)
                     /codon_start=1
                     /gene="phuG"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 315.2; E-value: 6.8e-96)"
                     /gene_kind="transport"
                     /note="photobactin transporter"
                     /product="putative cytoplasmic permease PhuG"
                     /protein_id="AAK95843.1"
                     /transl_table=11
                     /translation="MKKLIFSVANSVAQSDNRQFKFQRKGLLICGLLLVAFSVFSLFVG
                     TRPVTIKVTWEAFTAFNPANSEHLLVRYLRVPRTLLAIIVGCSLGVAGAIMQALTRNPL
                     ADPGILGVNAGAAVSIVSAIAFLGISECYWLYVVWSGRATIAGCGVYLLGGIRHGLNPV
                     RMVLAGAALSVVLLAVTQIITINSEDEVFNQFRHWVVGSLQGRGYEVLFPISILTASGV
                     IIALMLTKSLDTVALGHDLGKSLGVNQTKVWILSALAIIMLSGGATAAAGPISFIGLTA
                     PHFARLIAGPDYRWVLPYSMLISGVMVVAADSLGRVVGYPGEISVGIMVALIGGPFFVF
                     LVRKWKIVQL"
     gene            complement(13813..14853)
                     /gene="phuB"
     CDS             complement(13813..14853)
                     /codon_start=1
                     /gene="phuB"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 237.6; E-value:
                     2.6e-72)"
                     /gene_kind="transport"
                     /note="photobactin transporter"
                     /product="periplasmic binding protein PhuB"
                     /protein_id="AAK95844.1"
                     /transl_table=11
                     /translation="MGMRGFCIADPQSLSENARMKSMLTLVYGLVITLVTLSGGTVYAA
                     NTKNAAQTESLSWPRDFKNTDGTITTIPTKPQRILSTTVSITGILLSIDAPVVASATAT
                     NGKFFAQWDNVAQERKIEKLWPAGNIDLEMAYVVAPDLIVVSVSGADSAYAQVEQLKQI
                     APTIILDYGKQTWQDLATELGKATGLEDKVAARITGFNNYLAECRAKIAIPEGKVNIIS
                     YAGPGTINPISTSISPHALLLSQLGFTIESADPAWHNNANKTGDFVWAQYENITQLTAP
                     TTFLLSAGEHRAAEFLKDPVLANLASVKTGQVYGLGVNSFRIDYYSAKEIADSIVKRFG
                     IKQKAK"
     misc_feature    14851..14869
                     /note="ferric uptake regulator (fur) binding site; iron
                     box"
     misc_feature    14912..14930
                     /note="ferric uptake regulator (fur) binding site; iron
                     box"
     aSDomain        15254..16150
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbG_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="7.10E-68"
                     /label="phbG_Condensation_Starter.1"
                     /locus_tag="phbG"
                     /protein_end="299"
                     /protein_start="0"
                     /score="221.0"
                     /tool="antismash"
                     /translation="MPLTQAQQYYWHEFSLHSEKVVSTVAHYLDIQGNVDQEALCKAIT
                     MVISETDVLSVRFKRLEEERLPLQQPNQAATPQLKFIDLQTQPDPFNTALQLMRADVES
                     PLNLLTQLLSAQWLFKLSESHYLWYNRAHHILLDGFGIALIEHRCAHFYSYYLGKASAD
                     ASFHSLSSYLTEEQEYGNSEQYKKDRLYWQNYLSSARFPTVDIARADYSTKHHYTSCAL
                     SGDIVTGLTHLSADTGIAWPDLLVVLSSIYLLHYFATQTQNGEYSMPLWLPYMNRRTRF
                     RTNTPALMTNILPLLINT"
     gene            15254..16564
                     /gene="phbG"
     CDS             15254..16564
                     /NRPS_PKS="Domain: Condensation_Starter (0-299). E-value:
                     7.1e-68. Score: 221.0. Matches aSDomain:
                     nrpspksdomains_phbG_Condensation_Starter.1"
                     /codon_start=1
                     /gene="phbG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: VibH_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     328.4; E-value: 1.4e-99)"
                     /gene_kind="biosynthetic"
                     /product="putative photobactin biosynthesis protein PhbG"
                     /protein_id="AAK95845.1"
                     /sec_met_domain="VibH_like (E-value: 3.2e-182, bitscore:
                     595.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.2e-32, bitscore:
                     101.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTQAQQYYWHEFSLHSEKVVSTVAHYLDIQGNVDQEALCKAIT
                     MVISETDVLSVRFKRLEEERLPLQQPNQAATPQLKFIDLQTQPDPFNTALQLMRADVES
                     PLNLLTQLLSAQWLFKLSESHYLWYNRAHHILLDGFGIALIEHRCAHFYSYYLGKASAD
                     ASFHSLSSYLTEEQEYGNSEQYKKDRLYWQNYLSSARFPTVDIARADYSTKHHYTSCAL
                     SGDIVTGLTHLSADTGIAWPDLLVVLSSIYLLHYFATQTQNGEYSMPLWLPYMNRRTRF
                     RTNTPALMTNILPLLINTNPDETLETFLKKTINALHTQRTHARYRIEQIFLDHQLPQDT
                     RYLFSPLINVLPFDSPNFFDCQVKRHILTSGLYDCFSSNIIYRGKVDAGELIVDLDADS
                     AMFGKEEVENHQKNLTDFLQKVLTGNSLFLPVKALYS"
     CDS_motif       15320..15427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbG_0001"
                     /evalue="5.80E-12"
                     /label="C2_starter_024-063"
                     /locus_tag="phbG"
                     /protein_end="58"
                     /protein_start="22"
                     /score="38.2"
                     /tool="antismash"
                     /translation="STVAHYLDIQGNVDQEALCKAITMVISETDVLSVRF"
     CDS_motif       15647..15712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbG_0002"
                     /evalue="9.40E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="phbG"
                     /protein_end="153"
                     /protein_start="131"
                     /score="21.8"
                     /tool="antismash"
                     /translation="AHHILLDGFGIALIEHRCAHFY"
     CDS_motif       16067..16138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbG_0003"
                     /evalue="7.20E-05"
                     /label="C5_starter_265-294"
                     /locus_tag="phbG"
                     /protein_end="295"
                     /protein_start="271"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LPYMNRRTRFRTNTPALMTNILPL"
     CDS_motif       16217..16303
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbG_0004"
                     /evalue="1.40E-03"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="phbG"
                     /protein_end="350"
                     /protein_start="321"
                     /score="11.3"
                     /tool="antismash"
                     /translation="HARYRIEQIFLDHQLPQDTRYLFSPLINV"
     gene            complement(16627..19671)
                     /gene="phbF"
     CDS             complement(16627..19671)
                     /NRPS_PKS="Domain: Heterocyclization (12-243). E-value:
                     2.3e-23. Score: 74.9. Matches aSDomain:
                     nrpspksdomains_phbF_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (430-818). E-value: 9.4e-84.
                     Score: 273.2. Matches aSDomain:
                     nrpspksdomains_phbF_AMP-binding.1"
                     /codon_start=1
                     /gene="phbF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Cy_tandem"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     286.9; E-value: 3.9e-87)"
                     /gene_kind="biosynthetic"
                     /note="photobactin biosynthesis"
                     /product="nonribosomal peptide synthetase PhbF"
                     /protein_id="AAK95846.1"
                     /sec_met_domain="Cy_tandem (E-value: 1.4e-166, bitscore:
                     543.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-18, bitscore:
                     55.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-93, bitscore:
                     302.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGEVIIEFSVIRTRLTKLVQQYDALRTHIDESSLVQHVSDAII
                     LNLDEIDFTAIPRSAAYQKIDEMRQAYSHKIHDLSRSPWHIWVIKLAKPEDEDNDFFTT
                     VVFVSFDALILDGSAISFILFKLFEEDENEWKRSRPTGNIAHLLQPPSDSKKQSDTEYW
                     SEKLKEYSGPPTLPWKRPPESIKSSRYRREKVTVPSATLNHLSKIASSYGLFQNTILST
                     IILEIMSFWTQDSRLCLGVPVAIPTQKMQFSNESSFVAVCFKRDQVPFLERATAFQNDI
                     FASLEHLDFSGVDINRLIFNQHQTGLALPVVLTNGLSWKTLSASGDVSFYDGLTQTPQV
                     AMDIRLSLDQNKNLVLSIDYAEKALEKNIVQDILQTITQAITLICRQEKLAVDFSEVID
                     YHHYKDNGNDSDFICSNFLSRIADNLLTGKLKKTAIICGEQQITYSELGERVQKIVNNL
                     NRCGMRKGSVVAICLPRSPEHVMVTMACALLGIIWVPIDVNSPSERLDYLLTNCHSDLI
                     VSTGQFNSDKAVTLETLLTSVSDNVLLPLETLSSLSHSIEPAYYLYTSGTTGKPKCVVL
                     NNKATSNVIGQTLNKWEVKQDDVFISVTPLHHDMSVSDLFASLTVGATLVIPEPHAEKD
                     AIHWNRLVSKHKVSIWCSVPAILEMLIACQKGDSLSSLRLIAQGGDYIKPALIKEIRAT
                     YPDIRLLSLGGPTETTIWSIWHEITSEDVSLIPYGKPLPATQYFICNDINEHCPAFVTG
                     RIYTTGVNLALGYLEDGLVVQKDFVTITSPTGEQLRAFRTGDQGYYRKDGTIIFASRVN
                     GYVKIRGIRVSLPDIESELCKHPQINHIVVVDYPNEQNGDATLGAMYTTLNGQEILASE
                     WRDFSHGLLPVSHIPTRFAHIQAFPLSANGKTDRHQIRAFFTQPKPDNLTDKQSVISEN
                     QSVNNSAEDEHYQLILGIYLHAIGAQPLTGLNEDSEFLALGLRPSHLKEIARRLTEKFG
                     VILTPQLLVKCRNARQVSSLLSQSI"
     CDS_motif       complement(17188..17253)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbF_0004"
                     /evalue="2.00E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="phbF"
                     /protein_end="828"
                     /protein_start="806"
                     /score="14.1"
                     /tool="antismash"
                     /translation="FASRVNGYVKIRGIRVSLPDIE"
     aSDomain        complement(17218..18381)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbF_AMP-binding.1"
                     /evalue="9.40E-84"
                     /label="phbF_AMP-binding.1"
                     /locus_tag="phbF"
                     /protein_end="818"
                     /protein_start="430"
                     /score="273.2"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="KKTAIICGEQQITYSELGERVQKIVNNLNRCGMRKGSVVAICLPR
                     SPEHVMVTMACALLGIIWVPIDVNSPSERLDYLLTNCHSDLIVSTGQFNSDKAVTLETL
                     LTSVSDNVLLPLETLSSLSHSIEPAYYLYTSGTTGKPKCVVLNNKATSNVIGQTLNKWE
                     VKQDDVFISVTPLHHDMSVSDLFASLTVGATLVIPEPHAEKDAIHWNRLVSKHKVSIWC
                     SVPAILEMLIACQKGDSLSSLRLIAQGGDYIKPALIKEIRATYPDIRLLSLGGPTETTI
                     WSIWHEITSEDVSLIPYGKPLPATQYFICNDINEHCPAFVTGRIYTTGVNLALGYLEDG
                     LVVQKDFVTITSPTGEQLRAFRTGDQGYYRKDGTIIFASRVNGYVKIR"
     aSModule        complement(17218..19635)
                     /domains="nrpspksdomains_phbF_Heterocyclization.1"
                     /domains="nrpspksdomains_phbF_AMP-binding.1"
                     /incomplete
                     /locus_tags="phbF"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(17365..17427)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbF_0003"
                     /evalue="8.30E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="phbF"
                     /protein_end="769"
                     /protein_start="748"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AFVTGRIYTTGVNLALGYLED"
     CDS_motif       complement(17944..17997)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbF_0002"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="phbF"
                     /protein_end="576"
                     /protein_start="558"
                     /score="23.4"
                     /tool="antismash"
                     /translation="AYYLYTSGTTGKPKCVVL"
     aSDomain        complement(18943..19635)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_phbF_Heterocyclization.1"
                     /evalue="2.30E-23"
                     /label="phbF_Heterocyclization.1"
                     /locus_tag="phbF"
                     /protein_end="243"
                     /protein_start="12"
                     /score="74.9"
                     /tool="antismash"
                     /translation="IRTRLTKLVQQYDALRTHIDESSLVQHVSDAIILNLDEIDFTAIP
                     RSAAYQKIDEMRQAYSHKIHDLSRSPWHIWVIKLAKPEDEDNDFFTTVVFVSFDALILD
                     GSAISFILFKLFEEDENEWKRSRPTGNIAHLLQPPSDSKKQSDTEYWSEKLKEYSGPPT
                     LPWKRPPESIKSSRYRREKVTVPSATLNHLSKIASSYGLFQNTILSTIILEIMSFWTQD
                     SRLCLGVPV"
     CDS_motif       complement(19318..19359)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_phbF_0001"
                     /evalue="3.30E-03"
                     /label="Cy3"
                     /locus_tag="phbF"
                     /protein_end="118"
                     /protein_start="104"
                     /score="10.9"
                     /tool="antismash"
                     /translation="VVFVSFDALILDGS"
ORIGIN
        1 ttaagcacca agcgttgcac caccatcaat gacaatatct tgtaaagtaa tatgacttgc
       61 gagatcagag gccataaaca agaccgcatc agcaatttct gttggcgtcg ctatcttccc
      121 tagtgggata ccaagtttaa acaattcaga aaacccctga atgacttgct gtttggacgc
      181 ttctgtttgc cacataccac gctgcattgg cgtatctgtc gatcctggtg aaataagatt
      241 acaacgaacg ccataaggtg ctaattccag cccaacactc aggcagagac tacgcaatgc
      301 tgctttagat gcgcaatagg ccgacatgcc aacacgagga acatgagccg catttgacgc
      361 aatagtgaca attgcccccg ccttttggcg ttggaactgg agaatagtcg cctgaaatag
      421 gttgaatgcc cctcccgcat tgacagacaa gcactgttgc caatcttcaa acgttatctc
      481 ttcagcaaca ccaaggcgta agatcccagc tccattgacc agcacatcaa gttgcggttg
      541 ttgtgcaagg agttgttcac aacagcgcga aacggcaata ggatcgctga tatcaagcaa
      601 atacggcgta aaaggcaaat ccccctcagg gaacgtgatg tcaaacccaa ttaccttcgc
      661 gcctgcttgc tgaaaacgat aagccgtctg ataaccaata ccgctaccgg cacccgttat
      721 ccagacaatt ttatcgctaa aatcaagcgc aatactcatt tcaggctccc tgacgctcag
      781 tgaataatgt catccaacca tttattgttg gatttttcat taacgaaatg aaatccattt
      841 catatccttg ctgacgccaa tgggaaataa gagacataat gcgcacagaa tccagcccat
      901 aatcgagcaa gttctcatca tcaccaatat cgtcgctatc ctcatctaat aaaggcagta
      961 ataacgcttt gaggcgggtt ttattccatt gcacttgttt tacgtctaag gcaacaagaa
     1021 gctgctcggt agtctccaca cgtccacagc gcccagcggt atatttaagc gccatcatat
     1081 gttcttcata actgaaatcg gctaaagcat ccgcaaccat aaaaggctgt atatcacgca
     1141 tgaacgcgtc agtcgctgtc attagacagc caatatgtgc ataaacgcca caaataataa
     1201 gttgatcacg cccagctatt ttgagctgtt gctcaaaatc agtgcgctga aatgcgctgt
     1261 atcgccattt atccatgaca atatcaccag cctgaggtgc gagcgcatcg gtaatttttt
     1321 gcagttcagg gtggcagttc agccccggtc cccacatatc atttaacagc gccctctcct
     1381 catcactttg ctggttaggt tgagcggaat aaaataccgg tattccattt tcccgacaga
     1441 tttctatcag cctggcaata ttagtcacga cttgattaat taatggacta ttttcttccc
     1501 agaagttaag aaagtaattt tgcatatcat gaattaataa tgcagcccga tttttatcca
     1561 acgaccaatt gaccttgttt gtcggcagtc cttctgccac gggtaagtca taactattaa
     1621 gtttaggaat gctcatttct ttctccaacg agtgatggct gaacaaattg tttagtaagt
     1681 tgacgtaatt gttttttgtc tatttttccg acaggtgtta tcggcagtga gggaacaggt
     1741 tcaaaccggt caggcaattt ataatctgct attccctgct cacgcagata acgccgtaag
     1801 actacggctt ttatcggttt tcgtaatacg acaaaagcac agcttttttc acccattagc
     1861 ggatcaggaa tagcgaccag cgcagcataa atgacatcag ggtgccgaag cagcagattc
     1921 tcaatttcct cagccgcaat tttttcccca ccgcgattga tttgatcttt ttcacgcccc
     1981 acgacttgta aataaccatc aggtgccatg atgacgagat caccagaaca gtagaatcca
     2041 ttactatcaa aacattgctg attatgctgt ggactgcggt aatatccgcg gaaggtataa
     2101 ggcccctgag tcatcaaccg gccagcgacg ccgggaggaa caggattgcc atcattatca
     2161 gcaacccaaa cttcatcatc ctgactggtc gggcagcctt gtgtcgtaaa aatatgctgt
     2221 tcgtcatcat ccagccgggt atagttcact aatccttcag ccataccgaa aacttgttgt
     2281 agctggcatc ccatctcttt tggaatacgt cttgccagac tttcgcttaa ccttgcccca
     2341 ccgacctgta gcaatcgcaa gctttttagt gcatcacggt taccactaag tgctatcgcc
     2401 tcaaaccata cactgactgc tggcggtatc aatgcagtaa cattcacctg atgttgctgg
     2461 attagcggaa aacagcaatc agcactgggg ttattcgcta aaatgacctg tcccccgctg
     2521 taaaacgccc ctaatgcccc cggtgagctc ataggaaagt tatgcgcagc aggaagtgca
     2581 cataaatagc gagtttcagc attaaactgg caaatgtcca cactggcgcg aatactgtag
     2641 taataatcat tatgcgttcg gggaataagt ttaggtgtcc ccgtactccc ccccgacaat
     2701 tggaaaaatg caacttcatc agccggtgtt ggatcagcga taaaatcacc agcaccttct
     2761 gccaatagtg tctcaaaatc caaaatactg tcattatcac cacgtaagac aacgtgactc
     2821 aaagacggcg tacaggctct gagttcatca ataaaattgt cgtcgctaaa caaggaatgg
     2881 ttgcgatcgg caattaacaa tgcggggtta atctgatcag cataagcaca aagttcacta
     2941 cgctgatggc tatatatagc gttaaccgga actaccccaa gccgtaataa ggcaaagaaa
     3001 acaatataaa actcggcctc attccccaat tgaactaagg cggtttgtcc tcgtttaacg
     3061 ccttgtcgtt gtaatgctgc ggctaaacta tccaccagca gattaagttc agcatagctg
     3121 aactgacgat ctccacagat aagcgcaatt ttcccgttgt ttgactgacg ggtaaaaatg
     3181 tcgctaagcg ggagatctat ccaataacca agttgacgat agcgctgttc cagcgctttt
     3241 ggccaacgat taaattcaac tatcatgccg ggcatgcctc ctgtgaaaac tcgaatgcac
     3301 gcatcatcgt tgaaaactta acctctgttt ctgccactct gactctggtt tcgaatcagg
     3361 cacaatgcct gctcccgcaa acagtcttac ccgcgagcca tttacttcac cacaacggat
     3421 agtcaccacc cattcaccgt tccctttctc gtcacaccac cccacaatgc cgccaaagag
     3481 gtttcgttta aacggctcta attcctcaat taggtttttc gcggtctgat acggtgtgcc
     3541 gcaaagggcc ggagtaggat gaagcaggca agcaatagaa agtgcatttt cctgtggtgc
     3601 cttcagctct ccctcgatat cggtggcaag gtgccaaagt acaggcgtgc tgatggtgga
     3661 aggcatttca gagatatgta gtttttgaca acggctttcg agtacgtttc tcatcatatc
     3721 ggtcactaac cgatgttcat aattatcttt gacggactga ataagcgcct gacgcaattt
     3781 gtaatcttct tgctggtttt cactgcgctt tgctgaacct gccagcggct gagaaaagat
     3841 agtatttccc tgtttacgta ctaataattc tggactcgca ccaatcaatg ccccattttg
     3901 caacggaaca tggaaattat aactccaact attttgctga tttagatgtc gtaataattg
     3961 aattgaatct aatggctgat gggtttcgat gtcgagtaac cgcgaaagga caattttatc
     4021 tagtctatga ttacgcattg catcaacggc agtgttcacc atctggctaa agtgtgcttt
     4081 atcaggccac tggtgcgtct tttttctgta taagttgaat tggaaataag cgtgggaaac
     4141 tgctttcttt ggaaccaatg cattgttcag ggacaaaaag tgccgcattt tgctgtttat
     4201 cgaatggaat tgcccccacc agaacaggat tttcaatccc atctctcttc gcttgctgga
     4261 ataattgacg tatttcttgc tgaatcaggc tatcaggatt tgctgcatca tcaagtggct
     4321 ttgacacaat tgcatattgc ccctgcgcca acagactttt actggatgaa agaaacagaa
     4381 aatccttatt attaagatca ttaaaaccag tcagcaaagt atttctatat agatctggca
     4441 caagttttac ctctatctgt taatcgtgtg atcacgaaaa tggaattctt gtctcgacat
     4501 aactttgcat cacttgctat aaataaaacg atgacttaaa ttaccaataa taaaatttcg
     4561 atatgattta attttataaa aatttatatt tttaaaacat ttctccctta ttccatttag
     4621 agatctcatt tcgtaccatc ctgttattct gcctgatctt aaaagtggtt gattgaatct
     4681 atcaggcata tctcaacgat attcatatta ttttaataat aataattatc aatgttatta
     4741 aaaaatacat ttaaaaatca tatctatccc tttgtaaaac gccgtccctg cggaataatt
     4801 aagggagtat ggctgacggg atcatcaata atgacacaat cgaggccaaa aacctcagag
     4861 actaatgttg tcgtaatgat ctcaccaggt gccccttcca ccacaatccg tccccccgcc
     4921 atcacaatca aatgatctgc atatcggcaa gcctgattca aatcatgaag tacagcaatg
     4981 agcgtatatc cggatccttg attaaggtga caaaacaact caagcaactc aatttgatga
     5041 gcaatatcaa gataggttgt cggttcatca agcagtaaca atggcgtttg ttgagccagc
     5101 accatagcaa cccaaacccg ttgacgctgc ccacctgaaa gttcgtcaac aacgcattca
     5161 gcaagctcgg ttacaccggt cgcattcatt gcctggcgca ccgcttcata atcctcatga
     5221 ctccattgac gtaataaccg ctgatgagga aaacgcccgc gcgcaactaa atccacaact
     5281 ttgatcccct gaggagcctg cacgctttgc ggtaataatc ccagctgacg agccaaagca
     5341 cgggttggta tcgtgtgaat atcatgacca tcaaggcaaa ccctgccata ttccgggcgc
     5401 agcagacgac ataaacttct caacagcgtg gatttaccac aaccattagg accgataatc
     5461 acggtaaaac gaccatcagg gatacgcaga ttcagttcat cacagacgat atgttcaccg
     5521 taacccaggc gcaattcttc cacactcaag cgacaaggtg ataaaacaca ttggttatta
     5581 tgttctagcg ttagcgttgc catcaattct ctcacaaaaa cgttatcaat cagtctgcat
     5641 caatattcat atcaatgcag actgcaagag gattattcaa tgttgcatag aaaccctgat
     5701 attcaaaggg tatccatgca ctcggataat cttggcaaga tcgccttaag cggtatattg
     5761 ctatcctgtg tttttgcaaa cagcgccaaa atgccattga tagcctctga tatttgagag
     5821 atttgagccg cactataacg atctgaacga taattaaata aaacgcgtac catttcttca
     5881 cctgcaatca tctcttccat aatttcaaag tgaagcccca gtagcgattc ctgcttttct
     5941 aaaacaatct gctgaaatgc aatatggctt ccatccagca tatggaactc accgctcnaa
     6001 ctattttttg catgtaactg aatatatacc tcgaataaat gatcttttcc ttgatctgtg
     6061 tggcctgata aggcttcttc aatcagatca acggggatat cggtataagg caacgagtca
     6121 ttgatgttgt tcttaacctg agtgatcaga tcagtaaatg tcatctgttc agtaaagcga
     6181 accctgtgta tcacaaccgt ggtgaaataa ccgacagtgt caaagaagct cgcatcatca
     6241 cgccctgaag ctgatgttcc cacaataaga tcatcggttg cccccagtaa attgagcgac
     6301 gcaacaatac tggcgtaaag aatattaaag aatgaagcgc cattttttct ggcaagtgac
     6361 tgcaagcctt gagccaccac tttttcaatc tcaaactcaa tgccttcaca ggaattcgcc
     6421 tgcccagata actcgctggc cgcattttta aaaataggct ctccgcttgg cgcgccccgt
     6481 aaattattaa cccaataatc aagatgagac tgattcattc cctcattatt ttgcctgatt
     6541 gcatattgaa ggaagggtaa gggttgctct tgccatgttg gcgtctcatt tatcaatctg
     6601 tatttatagg catgtttcag ctcttccatc agcaaagtaa cgagaccact catcaagtgc
     6661 cacatgatga aataacaggg ataaaaactg ctgcctgagg cgttatcagt gacaaattta
     6721 atgcgcaaag gcagttcttc agatagatca aactgatatt tcccctcttt ttttaatatt
     6781 tcttctgagg aaagggaacc atattcatat gaaccccaaa accactgata atccgataaa
     6841 tccttcattg gaacgacacg ttgatagact tcgccctctt cctgataaaa taggctacgt
     6901 aatacagaat gtctttgcag tacatcaaaa aaagcttgct caagtacctg ctcattaata
     6961 attgcagaaa attttaaaat aaaaggtaag ttgaagatat cgttgaaatc aaatgccgca
     7021 tacgctttcc atagagattt ttgcgcaagg gataaaggtg cgacagccga aatatcttct
     7081 ttagattgtt cttcgctcaa ttcatcttta ttttcatcaa taggatcatg acattgcgca
     7141 tattcggcaa gtttcaacgc cgtcggataa ctaaagagat ggttaatatg gatttctata
     7201 ttatgtaagc tcagtaatct gcctatcacg cgggtggcaa tgagtgaatg cccgccaaga
     7261 tcgaaaaagt catcactggc tgtcatttcc ggtgaagaaa gcgcttgtct gaattcattc
     7321 aggataatat tggctatttt acgatggcta tcgcttttgt cagttgcttc atgttctttt
     7381 tgctgtttgg cgataataaa tgctgtatca ctgatatctt gatgtttttt cttcggtgga
     7441 agcagaaaaa cagacgtaag ttttggcgca atagtgacat tttgttcatg aataaatgtg
     7501 ccaaaaccct ctaacagaaa tgcgccaata tgtggggata ttgacgagcc tgtgattaat
     7561 tcaaaaaacc attgcccctc attgacattt ccggcagcca gcgaaatatc aaaatgcgcg
     7621 ttcaacggtg gaataggtaa taactcaacc attgcatcat tcaacctgag tgatgattgg
     7681 gattgattaa gccaagtcac aaggatatgt gggctgtcat gcccgtactc tacctcatta
     7741 cccatttgta gattgccact ttctatctgc ctttcaatat cggcaattat tttatccagg
     7801 cttctgtcat cttggcacac acgcaacgac attaattctg agtagaaaaa tgggctgttg
     7861 agttcatcat gtgtatattc tgggtcgcac gatacactga tattcacgtc taaatgagaa
     7921 cctatcattg caatatagca accaaataat gctgctactg ttgccaatgc tgaatatgct
     7981 gttttctccg caggtaaaaa tggagcaagt acatcaatat tgatcgtagt acgatatctg
     8041 cccgcaaggc gatgatgaag agaatcatcg aggtaactga ttttacccat ctctttaatt
     8101 agcacgctcc tggtggtatc ggatttatag agccagggaa tgccaatctt tccagattca
     8161 ctggataacc atttagccga gattgccttt ctaaataaat cttctcttcc aaacccgata
     8221 gtcttcaagc cattattata ggcatcggaa agcagggtaa acatttgcgg ccatgacacg
     8281 ctatctctca gaatatgatg cacaatcaca cccaaaataa ccccacgctt gccattcata
     8341 aacaacatga atttgacggg tggatgttca tcaagctcga taggtttgca ctgatccgta
     8401 agtaacctat ttatcgcttc ttcatcagac tgaatctgat aaatttcgat aggagaatcc
     8461 gcggttggat cgcaatattt acgcaaatcg ccttcatcat caaaacgata cctaacatta
     8521 attccaacta tctctttagt cagaagctct aatgctctga tgagccggcc tatgttgata
     8581 tttcctgtca gtgaccaggc acaggcaaac tgaccggaag cgttaggatc ctgttgatga
     8641 tgaagccaca tcatctcttc aaattcagtt aagtcctttt cagtttcttg ggcttccgaa
     8701 gatgaatgac catcagcatg ggcattgaat acttcatcca aaagcaatgc ttcatcatct
     8761 gtcagtatcc gcttaaactc tcttgccata ttcccacttc tccagtcaac gcagggctac
     8821 atctacatat taatcttttg ccattttccg gacagaggat gtgatcccac tcatacaaca
     8881 accctccatt ttttgncggg tagaataagt ttcacgccac tgtccgtggc taacttaatt
     8941 aatcgcctta gaacttcagt tcaaacgtcg gcaccaatca ttctcgggac gctgataaaa
     9001 ttatcgaatt aacgttatta tccggaacta ataaacgttt atcagagtca aacagattct
     9061 gagcaaataa tgtggcgcgt ccccacttga agttataacc aagttgaagg ttagctatcc
     9121 aatatgctgg gatttttccg cgggcagaat tgtcatactg agagtaataa gtatctgaga
     9181 acataacatt gccgctaaca tcaatatcct cggtcagtaa atacttagcc aagaggtttg
     9241 cggtatatcc cggcgcccga ggtaattcat taccctgaac accactctcc gcgaagcttt
     9301 taatcttcgt tttcagcaag ccaatattag catttaactc aagtttttcg accggtaacc
     9361 aacgggcgcc gacttctgca ccatacgttt caaccttatt agcattacgg atcatggttg
     9421 aatcgagtga cagataataa ggcaactgca tatccttata atcgttgtag aaaagattag
     9481 aagtgagttc cagtttacca tccagcaagc tgttacgtgt ataaaggctg tagttccaga
     9541 catattcagg gtcataggta taactaatga caggcttgcc aaaggtcact cccgcccccc
     9601 ctgcgttata acctctacca accgctatcc cgacggtttg atctttctgc ggtttccagg
     9661 ctacatcaat tttaggcaga aaagcgttat aggttttatc aaaatcaatg gctacacttt
     9721 cgcttccccc tttacgtgtt ctgtgttcac gttcaaagcg gcttgataaa gtcacatcaa
     9781 tttcaggaac aaccgtgtag gtcaagacag tataagcaga ggctgtttcc gttttatcat
     9841 caaacttgct gcccccgaaa agattgatag tctcatcctg tttaccatgg aaataacgca
     9901 cacccaccaa accattcagc ttattatcaa acccttgaaa acggataata ggttcaactt
     9961 ctaactcttt gccatcagta tcagcttttg gaattttaga cgaggttaat ctgtgataag
    10021 caagatcggt ataaattaat ttattttcca gactaatggt atctgacaaa gcccatgaaa
    10081 tatcccagat cccactggtc gtttttcgtt ctacaactgg cctgaacagt tcatgcctta
    10141 aattaagcgt atcccttgga ttgtatgctt cgttctgcgg agcacgacta tcaagatggt
    10201 taaccgttaa tttggtggat aactcaggaa tggacagtgg ttcaaacagc agcttcgcac
    10261 ggaccgttgt tgattcaatt ttgtgcggat cgccaacagg atcataggaa accaggttag
    10321 caaagctatc acgattttga cgatcgacac taagacggaa ggccaattgc tcgtcaatca
    10381 aaggaccgga agccatcgca gcgacttgtt gatagccctg attagcgaac ccacttttga
    10441 ttgcgctctc ccaataaaag gtaggatcga gtgatttaat aatcacagcg cctgcaatcg
    10501 cgttccttcc ctgaatataa ctttgtggat cacgaaatac ctcgacactc tcgatatccc
    10561 ataaagattg cgtgccgaaa gctaattcat tataggtaaa cgagcgccca tcaatagaga
    10621 cgttgattct gggacgcgtc ccactaatga aagccattcc cccttgtgaa gggcctgaac
    10681 catcaacacc gcgaacagcg ggaagagcat tactaatacc attatcaaca acgttcggcg
    10741 tcatttgcag caacatgtta acatcaggat taggaataga tttcattttg cgaagattat
    10801 aaacctcgac acttgaacca ctatcgtaaa tagagcgatt gactttctct cctgtcacca
    10861 ctaacacatc ttcttctgat gatgatgcct tggtatttcc tttttgggcg ctttgcgggt
    10921 tcttttcctc tgccgcaata gcatcagttc ctgtcagagc aatggcacca aaaaataaag
    10981 ctccaaaaat acctacaaaa ttcgattttt cagtatgttc tttttcgtga tacatcatgt
    11041 tgcagagttg agtgcaacct attcattcat ttttctcctt tagccagctt acacgaaatc
    11101 gttttaataa attaaatgag ttaaatcgtg acattgctga ccggtggatc ccagtctgga
    11161 aaaaacatgg tgcgattcaa cccatgctaa tttcatgcag agtagtttct ttatgttatt
    11221 attactcttc ggtgttgctt tgttgtaata tttcttaaat agtaataatt atcataacaa
    11281 ggtgtattat tgtatgtaaa taaaaatcat tatcattaac tgtgatcaat gcaacagaaa
    11341 aataaatttt ccatataaaa caacttgtta ttttaaagaa ataaaaaaat aaaagataac
    11401 tcggtaaaat atgtggtttt aggaagttat ttagccagaa agaaattgac taagagtata
    11461 tccctatatt ttatagaatt aatttgagac ttaaaaaaca aaccagaaaa ataaagaaat
    11521 cattcacaag ctaagttaag aatataaata acgaaaatat tccatcaatt gagacagata
    11581 aagatcccaa aaaatatatt attatattca ttacctgaat gactattcct cctgatatcg
    11641 cctcccacat taagagaaaa cttacgacaa ttcttgctaa atttgccggg aacgggtcaa
    11701 caaccaaatc agataaattc cgccaacgag ccccgtcata agcccaatag ggactgccgc
    11761 tcgtaaaggt aaaagctgcg taagcagatc agctgacagc aaaagacaag cacccattag
    11821 cgcggcactg ataaccggca tatttctcga acaggtcagg cgaaccacaa gctgaggggc
    11881 ggccaaagca acaaaagcaa tcggccctgc ggcgccagtg gcaagagccg ctaaaaccac
    11941 agcgcagaat atcataataa gacgaacgcg ttccactctg ataccgagct gacaggcaat
    12001 atcatccccc atctcgataa tgctcagttt ccttgtcata aaaagaacca aaggcaccag
    12061 caatacaacc ccggttaaaa caggaaaaac atgtacccat gttcgggcat taagtgatcc
    12121 ggcaagccac aaatttgcca tcacggcatt atccagattt ccttttacca gtaataagcc
    12181 attcagggca cttagcactg aacccacacc aatccccgtc aggataaggc gatacccccc
    12241 tattgcgccg gattttaaag ataacagata cactaccgcc gcagtcaggg ttcctccggc
    12301 aacagcagca atcgctattt gcactgcatt attatcaaat aaaactatct gtataatcgc
    12361 ccccgtcgct gcaccgactg taaaaccaat cacatccgga gaacctaacg catttcggga
    12421 aatagactga aaaaccgcac cagatacccc cagtgccgca ccaacaaaaa ttgcgggtaa
    12481 cacgcggggc aaacgaatat ccatgatgat tttttcgctg acagaaccgg aacccggccc
    12541 ccaaaaaata gtgataattt gttcgattgt gatattgaat ttgccgatag tcatggaaaa
    12601 aagcgctaat accataatca acagcaacat ggcacaaatc accataagat ttctgggaac
    12661 gaaaacaaga gacacttttc cttgtcgcca gaccttaccg gaatattaac ctcagtctcg
    12721 ccataattcc gtttgctcat agttggacaa ttttccattt tctgaccagg aaaacaaaga
    12781 acggccctcc gattagcgcc accataatgc caacactaat ttccccagga tatcctacga
    12841 ctcgccccag actatcagca gctaccacca taacgccaga tatcagcata gaataaggaa
    12901 gtacccaacg ataatcaggc cctgcaatta aacgggcaaa atgaggggcg gtcaggccga
    12961 tgaaactaat gggccccgcc gctgccgtgg caccgccaga taacataatg atggccagtg
    13021 cagacagaat ccagactttg gtttggttaa cacccagcga ttttcccaga tcatgaccaa
    13081 gcgctaccgt atcaagagac tttgtcagca ttaaagcaat tatcactccg gaagccgtca
    13141 gtatggagat agggaaaagc acctcataac ctcgcccttg aagtgagccc accacccagt
    13201 gccggaattg attaaatacc tcatcttcgc tgtttatggt gataatctgg gtgacagcaa
    13261 gtaatacaac ggacagtgca gcgcccgcca ataccattct taccgggttc aacccatgcc
    13321 ggatcccccc gagcagatac acgccacaac ctgcaattgt cgccctgcca gaccaaacca
    13381 catatagcca ataacattcg gaaatgccca aaaaagcaat tgccgagaca atggaaaccg
    13441 ctgccccagc attgaccccc agaatacccg gatcagccag tggattacgg gtaagcgcct
    13501 gcataatggc acccgcgaca cccaatgaac aaccaacgat aatcgccagc aaagtacgag
    13561 gcactctcag ataacgaacc aataaatgtt cactattggc agggttaaaa gcggtgaatg
    13621 cctcccaagt gactttaatc gtgacagggc gggtcccgac aaaaagacta aaaactgaaa
    13681 atgccacaag taataacccg caaatcagca acccttttcg ctgaaatttg aattgccggt
    13741 tatcggattg cgcaacagaa ttagcaactg aaaaaatcaa ttttttcata tccaactcaa
    13801 acaattgcta agttatttcg ctttctgctt aatgccaaac cgtttaacaa tgctatcggc
    13861 aatttctttt gcactgtaat agtcaattcg aaacgaattc acaccaagac cataaacttg
    13921 tcctgttttg accgaagcca aattagcgag tacaggatcc tttaagaatt cagccgctct
    13981 gtgctctcct gcacttaaaa gaaatgttgt gggcgcagtt aactgcgtaa tattttcata
    14041 ttgtgcccaa acaaagtccc cggttttatt tgcattatta tgccaggcag gatctgccga
    14101 ctcgatagta aacccaagct gtgaaagcag caaagcatgt gggcttatgc tcgttgatat
    14161 ggggttaatg gttcctggcc ccgcatagct gataatatta accttacctt cagggatggc
    14221 aatttttgcc cggcattcag caagataatt attaaaacca gtaattctgg ccgcaacttt
    14281 atcttcaagc cctgtcgcct tgcctaattc agtcgccaaa tcctgccatg tctgtttacc
    14341 ataatctaag ataatcgtgg gcgcgatttg tttaagttgt tctacctgag catatgcgga
    14401 atcagcgccg ctcacagaaa ccacgattag atcgggcgcg acaacataag ccatttccag
    14461 atcgatattg ccggctggcc agagcttttc aattttccgc tcttgagcaa cgttgtccca
    14521 ttgagcgaaa aatttcccat tcgtggccgt tgcactcgca accacaggcg cgtcaattga
    14581 taacagtatt ccggttatcg aaacagtggt cgataaaata cgctggggtt tcgtcggaat
    14641 agtggtgata gtgccatcag tatttttaaa atctcttggc caggaaaggc tttctgtctg
    14701 agctgcattt ttcgtgtttg cagcataaac agtcccccca gatagagtga ccaaagtaat
    14761 taccaagcca tatacaaggg ttaacatcga tttcattctg gcattctcag acagtgattg
    14821 tggatctgcg atgcagaaac ctcgcatacc cattcagata atccaaagtg gacgtaatgt
    14881 atcattttgt ctaatatccg acaatgagat taataatgat tatcatatac aataacgttg
    14941 atcacgaaat acgtcacatt cttgttgtat cgcacaacaa atgtttcatt ttctcagata
    15001 taaaaccaat tcagatttca gccagaaaca atcaacgaaa aatggtgatc aaacaggaga
    15061 atgaatgtca tgggaataaa tgggcaatta tgtgttggct tgttcagacg ggaatattgt
    15121 gactcaacat tgcgtgaaca cctatcacaa acatagaaga aaattttatc tactttttac
    15181 tttttattct atttttctat gatgaatcca taaggtttac ccaatgttaa acatcactca
    15241 aacttctagc tggatgccat tgacgcaggc acaacaatat tactggcacg agttcagcct
    15301 gcattccgaa aaagttgttt cgactgtcgc tcactatctt gatattcagg gtaatgtcga
    15361 tcaagaggca ctttgcaaag caataacgat ggtgattagt gaaacagatg tgctctctgt
    15421 ccgttttaaa cgccttgaag aagaacggct tcctttacaa caaccgaatc aagccgctac
    15481 accacagtta aaattcattg atttacagac acagcccgat cccttcaaca cagcgttgca
    15541 acttatgcga gccgatgtgg aatctccgct gaatttatta acgcaactgc tatccgctca
    15601 gtggctattt aaattaagcg aatctcatta tctctggtac aaccgggctc atcatattct
    15661 ccttgatgga tttggtatag cgctcattga acatcgttgt gcgcatttct attcgtacta
    15721 tcttggtaaa gccagtgccg atgcttcttt tcactcactc agcagctacc tgactgaaga
    15781 acaagagtac ggtaacagcg aacaatataa aaaggatcgc ttatactggc aaaattatct
    15841 ttcatccgcg cgctttccaa ctgtggatat cgcccgtgcc gactatagca ccaaacacca
    15901 ttacaccagt tgtgcgctct ccggggatat tgtcacaggc ttaacacatt tatcggctga
    15961 tacaggtatc gcctggcctg atctgttagt ggtgctttca agcatctacc tgcttcacta
    16021 tttcgctaca cagacacaaa atggtgaata ttcaatgccg ttatggctcc cctatatgaa
    16081 tcgccgaacc cgtttcagaa ccaatacacc ggcattaatg acgaatatcc ttcccttatt
    16141 gataaacacc aatccggatg agacattaga aacctttttg aaaaaaacaa tcaacgcgct
    16201 tcatactcaa cggactcatg ccagatatcg tatagaacag atctttttag atcatcaatt
    16261 acctcaagat acccgttatt tattttcgcc actcattaac gtgttacctt ttgactctcc
    16321 caattttttc gattgccagg ttaaacgcca tatactcacc agcgggctct atgattgctt
    16381 tagctctaac attatctatc gcgggaaagt agatgctgga gaattaattg ttgatcttga
    16441 tgctgattca gcaatgtttg gtaaagaaga ggttgaaaac catcagaaaa atctgactga
    16501 ttttctacaa aaagtgctca caggaaactc gcttttcctg cctgtaaaag cgctttactc
    16561 atagaataaa aaataactta atatataaag aaccggggtc agactccggt tctttagaaa
    16621 aacaggttaa atactttgtg aaagcaaaga agaaacctgc cgggcatttc tgcatttaac
    16681 taacagctga ggcgtcagaa taacaccaaa tttttcagtg agacgccgag cgatttcttt
    16741 gagatgcgaa ggccttaatc ccagcgctaa aaattcagaa tcttcattca aaccagttaa
    16801 cggctgcgca ccaatggcat gcaaataaat gccgaggatc agttggtaat gttcatcctc
    16861 tgcgctgtta ttaacgcttt ggttctccga tataacagac tgcttatcag tcaaattatc
    16921 cggcttcggt tgcgtaaaga acgccctgat ttggtgtcga tctgttttac cgtttgcaga
    16981 caaaggaaac gcctgaatat gagcaaaacg cgttggtata tgagaaacgg gtaaaagccc
    17041 gtgagaaaaa tcccgccatt ctgaggcgag aatttcctga ccatttagcg tcgtatacat
    17101 agcgcctaat gttgcatcgc cattctgctc atttggataa tcaacgacga caatatgatt
    17161 aatttgtgga tgtttacata actcactttc aatatcaggc agagacaccc taattccccg
    17221 aattttgaca taaccattta ctctgctggc aaaaatgatg gtgccatctt ttcggtaata
    17281 gccctgatcc cctgttctga atgctcttaa ttgttcacct gtaggcgagg tgatagtgac
    17341 aaaatctttt tgcacaacaa gaccatcttc cagatagcct aaggcaagat tgactcccgt
    17401 agtataaatc cggccagtca caaacgccgg gcaatgttca ttgatatcat tacagataaa
    17461 atattgagtc gcaggcaggg gtttaccata aggaataagg ctgacatcct ctgacgtaat
    17521 ttcatgccat atactccaaa tcgtcgtttc agtcggccct cccaaagaaa gcaatcggat
    17581 atcaggatac gtcgctctaa tttccttgat gagagcaggt ttaatataat caccgccttg
    17641 cgctatcagt ctgagggaag agagagaatc ccctttttgg cacgcaatta acatttctaa
    17701 aatcgcaggc actgaacacc aaatagaaac tttgtgcttc gaaaccagcc gattccaatg
    17761 gatagcatct ttctctgcat ggggttcagg gataaccagc gttgcgccaa cagtcagtga
    17821 tgcaaagagg tcggaaacag acatatcatg atgtaatggc gtaacggaaa taaacacatc
    17881 atcctgttta acctcccatt tattcagcgt ttgcccgata acattagatg ttgccttgtt
    17941 attgagcacc acacatttgg gcttacccgt tgttcccgag gtatacagat aataagcggg
    18001 ctcaatgcta tgactcagtg atgataaagt ctctaaggga agtaaaacgt tgtcagaaac
    18061 cgatgtgagc agcgtctcca atgtgacagc tttatcacta ttaaactgtc cagtactcac
    18121 aatgagatca gaatggcaat tcgttagcag ataatccaga cgttcagagg gagaatttac
    18181 atcaataggc acccaaataa tccccaaaag cgcacacgcc attgttacca tcacatgttc
    18241 aggactacga ggcaaacaaa tcgcgaccac actgccttta cgcattccac agcgattcag
    18301 gttattcact atcttttgaa cacgttcccc caattcagaa taggtaatct gctgctcccc
    18361 acagataata gcggtttttt ttaattttcc cgtcaatagg ttatccgcaa tacgagacag
    18421 gaaatttgaa cagataaaat cactgtcatt accattatct ttgtaatggt gataatcaat
    18481 cacctcagaa aaatccacag cgagtttttc ctgacggcag atcaacgtta ttgcctgagt
    18541 gatggtttgt aaaatatcct gcacgatatt tttttccagc gctttttctg cataatcaat
    18601 ggataacacc aaatttttat tctggtccag ggacaaacga atatccatcg caacttgcgg
    18661 tgtctgcgtt aatccatcat aaaaagagac atcaccagat gcagacaatg ttttccatga
    18721 caaaccattc gttaacacaa caggtagcgc taaacctgtc tgatgttgat tgaatatcag
    18781 cctgttaata tcaacgccgg aaaaatccag atgttccaga gaggcaaaaa tatcattttg
    18841 aaaagctgtc gctctttcta aaaatggcac ctggtctctt ttaaaacaaa cagcgacaaa
    18901 tgaagattca ttactgaact gcattttctg ggtgggaata gcaacgggaa caccgagaca
    18961 taaccgacta tcttgtgtcc aaaatgacat tatttccagg ataatagtag acaaaatcgt
    19021 attttgaaac agaccataag atgaagcgat tttagacaaa tgattcaacg tcgcgctggg
    19081 aacggtgacc ttctcccttc tgtagcgaga ggatttaatc gattctggcg gtctcttcca
    19141 aggtaacgtc ggtgggccgg aatattcttt cagcttttct gaccaatatt cagtatcact
    19201 ttgctttttc gagtcagaag gcggttgaag caaatgagcg atatttcccg ttggcctgga
    19261 tcttttccac tcattctcat cttcctcaaa caatttaaac aagatgaaag agatagcgct
    19321 gccatccaaa atcagtgcat caaagctcac gaacaccacg gtcgtaaaaa agtcattatc
    19381 ctcatcttct ggctttgcca atttaatgac ccaaatatgc cagggagagc gagaaagatc
    19441 gtggatttta tgagaatacg cctgcctcat ctcatctatc ttttgataag ccgctgaacg
    19501 cgggatagca gtgaaatcaa tttcatcaag attcaggata atggcatcgg agacatgttg
    19561 aaccaatgaa ctttcatcta tatgggtacg taacgcatca tattgctgta ctaatttggt
    19621 gagccgggtc ctaataacag aaaactcgat tatgacctct cctgaaatca t
//
