LOCUS       BGC0002499             24026 bp    DNA     linear   BCT 11-JUL-2022
DEFINITION  Streptomyces achromogenes subsp. streptozoticus enteromycin
            carboxamide biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0002499
VERSION     BGC0002499
KEYWORDS    .
SOURCE      Streptomyces achromogenes subsp. streptozoticus
  ORGANISM  Streptomyces achromogenes subsp. streptozoticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:50:38
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..24026
                     /country="USA"
                     /db_xref="taxon:285532"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces achromogenes subsp. streptozoticus"
                     /strain="NRRL 3125"
                     /sub_species="streptozoticus"
     subregion       1..24026
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002499"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24026
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             26..871
                     /codon_start=1
                     /note="Orf-2"
                     /product="RNA polymerase sigma-F factor"
                     /protein_id="QSI97698.1"
                     /transl_table=11
                     /translation="MMATTTVQRTGHATDVPEIADPSKVAPKDARELSKLFFDQLTVLE
                     EGTPEYQYARNTLIEMNMSLVRFAAGRFRSRGPEEMEDIVQVGMIGLIKAIDRFELSRE
                     VEFTSFAIPYIVGEIKRFFRDTSWAVHVPRRLQEARVQLARANEELRSRLGRTPTTKEL
                     SELMCLPEDEVVEAQLASNGYQSASLDAAINGSEDGEAALADFIGADDAALGLIEDFRA
                     LAPMIAELDERDRRIIHWRFVEELTQAQIGERLGVSQMHVSRLLSRLLARLREGMLSTD
                     "
     CDS             complement(990..1655)
                     /codon_start=1
                     /note="Orf-1"
                     /product="heterokaryon incompatibility protein S"
                     /protein_id="QSI97699.1"
                     /transl_table=11
                     /translation="MLIEGYDGGPLVAGEPLLARPGFWPNHLWGRCGPAGDVEPEWFGD
                     DGADVDAMSEALLDPGRWPVFRVPVAGGYGLVAVYRNCVDDYGVDYLITPPGRGRAQHL
                     AVRQGDLEGETLRWGELVRIAGSPGAAAEGIEDPAARLLLLLPLLVEHALPGGATATLG
                     AALIAVGAPRDTAPLTARRLLGHSGGKTWHDPAWGSPLSGSGSPTPPGSGLLARLGIA"
     gene            1931..2797
                     /gene="etmA"
     CDS             1931..2797
                     /codon_start=1
                     /gene="etmA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmA"
                     /product="p-aminobenzoate N-oxygenase AurF"
                     /protein_id="QSI97700.1"
                     /sec_met_domain="AurF (E-value: 2.9e-39, bitscore: 125.6,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVLIDQNDRFLDILERLSSKSVEDYYNPYKLFEWPDQLPQNMW
                     WMSPELTTTYGTAAAERLTEEQLYALSRHESINFYSLNVHGIRELLIEVTRRIHTSGFE
                     TPSQFFHHFIGEENEHMWFFAEFCLRYGNKIYRQPAGATAEIPRSDVESLLVFARILIF
                     EELVDHFNSKMALDTRLHETIRAINRIHHQDESRHIAFGRELVSALFAEVKKNSTEQEL
                     ADVSAYIKRYMKYSFESLFNPQVYRDAGIEKPQELRRELLEAPTRAEFEQSVFRKTGKF
                     LEKVGII"
     misc_feature    1931..21384
                     /note="enteromycin carboxamide biosynthetic gene cluster"
     gene            2797..3645
                     /gene="etmB"
     CDS             2797..3645
                     /codon_start=1
                     /gene="etmB"
                     /note="EtmB"
                     /product="amino acid-[acyl-carrier-protein] ligase"
                     /protein_id="QSI97701.1"
                     /transl_table=11
                     /translation="MPPTTQQDIGTGDALVILPPDQTDLLRELDAVFSGWGRAQGAREI
                     LPPPVYPVRDLEKFDVYTNFPHLALVGAALDLDTGSGKPADGRFAPGSLLGAQLGLPHA
                     TCYGAYLYHENTRVPDQTLITLVNRCFRNEEHYGGLRRLLSFQMREIVALGTYEHTQET
                     IARFTERILEFSRALSLGLEKVAATDPFFENDGGRALLAKLSPVKYEFQAGDLAIASVN
                     THRNFFGERCNIRRENSDEHAFTSCVAFGLERWLAVLLDQHDGDAHKALEAVRAAAGQV
                     S"
     gene            3647..4063
                     /gene="etmC"
     CDS             3647..4063
                     /codon_start=1
                     /gene="etmC"
                     /note="EtmC"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="QSI97702.1"
                     /transl_table=11
                     /translation="MLPGRIGIDLVPFARVSRLLSPEAEPVLPRMLSGEEIGLCVTDTG
                     PDIPGIAGRLAAKEAVFKLFHAAGQPMPWLGIEILKENGGRPVVRLSGRAARLARDARV
                     GHIEVSIAHDDPFAVAVAFCDTATDREAHQLESA"
     gene            4081..4320
                     /gene="etmD"
     CDS             4081..4320
                     /NRPS_PKS="Domain: PP-binding (17-72). E-value: 5.2e-09.
                     Score: 28.4. Matches aSDomain:
                     nrpspksdomains_etmD_PP-binding.1"
                     /codon_start=1
                     /gene="etmD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmD"
                     /product="acyl carrier protein"
                     /protein_id="QSI97703.1"
                     /sec_met_domain="PP-binding (E-value: 2.2e-09, bitscore:
                     28.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASAGIEEIRSWILSRHPERTDVAPDENLIESRLVDSLSFVELVY
                     AIEGASGIEIDFDTIDIRDFQTLSSIEKAFFATV"
     aSDomain        4132..4296
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_etmD_PP-binding.1"
                     /evalue="5.20E-09"
                     /label="etmD_PP-binding.1"
                     /locus_tag="etmD"
                     /protein_end="72"
                     /protein_start="17"
                     /score="28.4"
                     /tool="antismash"
                     /translation="PERTDVAPDENLIESRLVDSLSFVELVYAIEGASGIEIDFDTIDI
                     RDFQTLSSIE"
     gene            4342..5169
                     /gene="etmE"
     CDS             4342..5169
                     /codon_start=1
                     /gene="etmE"
                     /note="EtmE"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="QSI97704.1"
                     /transl_table=11
                     /translation="MEAVSYTAQWTAAARALESERTGDAMFEDPFARALAAPRGFELLD
                     RYGGGGLVPFIAIRTRYFDDSVETVLRDGEVRQVVLVAAGMDTRAYRLTWPAGTTVYEI
                     DHEALMEEKRDRLARLGARAGVERVEVKADLAGDWLPTLKQAGFDPARPTLWIAEGLMF
                     FLTEDQVVHLLRTLGSASAPGSWLAVDFVSKALLRSPFSQSFLKGLKEDGTPWLFGTDE
                     PEDFLAASGWKVRDLREPGDPGAGEGRWPYEVQPRDRRGVSRSWLVRAEYAGS"
     gene            5179..6129
                     /gene="etmF"
     CDS             5179..6129
                     /codon_start=1
                     /gene="etmF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 123.8; E-value: 1.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmF"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase"
                     /protein_id="QSI97705.1"
                     /transl_table=11
                     /translation="MSTATTLERIESFLPERSVRIDDVAGSLGLRRAEVGVFRKIYGLD
                     RLRFDPDTGLFDLVLPAARRALDALPEGRRVEYVIYAHTVQAVAPPHVDTAATIRDGLG
                     LHDAEAFALTHQACVSSLGAIDLAGELLRAEAPEGAYALMVTGERAYSPKVQLIPNSAI
                     MADAAAACLVTVGGPGDEVLSFVTRTLGEYAAGLEMTREETQGFGQVYGTVLGEVINEA
                     VDAAALSFDDVDLVIPHNVNMVSWRQTIKEMGADPEKFFLDNVAQYSHTYASDVFVNYT
                     TLRDRDRLTDGRYYVLVSVGLGATFGAMVIRHRKR"
     gene            6135..7535
                     /gene="etmG"
     CDS             6135..7535
                     /codon_start=1
                     /gene="etmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmG"
                     /product="aspartic acid-holo carrier protein ligase"
                     /protein_id="QSI97706.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.4e-07, bitscore:
                     21.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.2e-08, bitscore:
                     25.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDDGYTAGLKQALTGDRDARFVWLCNFEVENQWARSYTGLPAA
                     RGSATAATVQRMEELGALLAEPADYLLLDRPLDEGYRSYAEKTGLGAPVELVTAAPAAD
                     GGTGAAVLDSPELLERLRRIARDGAYLMPMGNSVQEERIAELTGLRLAVPDAATCERVN
                     SKIYSRRAAEELGLRTIPGFCCETVGQLRRALDEGLRDDRPVIVKDAYGVSGKGLLILD
                     SRRKADRLLRMVERRAANRGDDALHVVVETFLPKRFDLNYQFTVDRRGRVRLDFVKQAL
                     TSGGVHLGHVMPADLTPAQQDELAAAAVALGARLYADGFFGVVGVDALLGADDRVYPVL
                     EINARLNMSSYQGRVTERFGRPRGAALARHYPLRLAEPLPFEAVTDALGDLAEPPHDRD
                     GLVITCFGTVNAQAGDALAGVPRGTPAPHFNGRLYTMLFAGNREGLDVLDRRVEAALDR
                     LNTAGRTP"
     gene            7532..8812
                     /gene="etmH"
     CDS             7532..8812
                     /codon_start=1
                     /gene="etmH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 383.3;
                     E-value: 1.6e-116)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmH"
                     /product="L-glutamyl-carrier protein decarboxylase"
                     /protein_id="QSI97707.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2e-46, bitscore:
                     149.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.8e-20,
                     bitscore: 61.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRELHVQGIPVSEIAEEFGTPLFLYDADVLHSVYTSLRERLHP
                     AVDIFYSLKANPNISVCGYLASLGAGAEISSMVELMTVRRAGVAPENVIFLGPGKTRAE
                     LEACVTAGIHAVVCESLEEVALLEEIAAGLGRDDVTVLLRINPDFHTKGSGLAMGGKPR
                     QFGIDADTLRRSREQLAALRRVRVRGFHAYMGTRFLNADDLVHNTREILALAADLSERL
                     GIVPETVDFGGGFGVAYFDNEKSLDIETTVAGINEAVASFTAKYPRCRLINELGRYLVA
                     ACGTYVVRALYVKESLGEKFVIADGGTNHHMAAVGIGSFVKRNFPIRSLSRHGEEAADT
                     YTVTGPLCTPNDVIGKKVQLPPVAPGDLIGVELSGAYGPTASPGLFLSHGFPAEVLVHG
                     GTAHLVRERDRKEDLLDKQRLVDFTRH"
     gene            8844..9104
                     /gene="etmI"
     CDS             8844..9104
                     /NRPS_PKS="Domain: PP-binding (9-77). E-value: 2.7e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_etmI_PP-binding.1"
                     /codon_start=1
                     /gene="etmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 57.9;
                     E-value: 1.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmI"
                     /product="peptidyl carrier protein"
                     /protein_id="QSI97708.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-10, bitscore:
                     32.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHDVVNAVEKALSEVLEQPVTGLTEEVRLFEDLHLDSTSVLEM
                     LMALEDAIDISVDPENLDMDDFKSVGTLTDYVLSQQTTSGV"
     aSDomain        8871..9074
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_etmI_PP-binding.1"
                     /evalue="2.70E-10"
                     /label="etmI_PP-binding.1"
                     /locus_tag="etmI"
                     /protein_end="77"
                     /protein_start="9"
                     /score="32.6"
                     /tool="antismash"
                     /translation="VEKALSEVLEQPVTGLTEEVRLFEDLHLDSTSVLEMLMALEDAID
                     ISVDPENLDMDDFKSVGTLTDYV"
     gene            9117..9950
                     /gene="etmJ"
     CDS             9117..9950
                     /codon_start=1
                     /gene="etmJ"
                     /product="EtmJ"
                     /protein_id="QSI97709.1"
                     /transl_table=11
                     /translation="MPALLAACGVVAPPRRSPEPTLSNLSYYRDLVEPFGLEVDETLLR
                     SAPHVGHRDLVDRLVAASGTDGSDPDLVIVTHALPDITPFTAMAPYLDRLLGGRAVNFG
                     IHQQGLAAPFTALRAVSAFQRAGRSQRAVLAVLEQTTLPTRFPLVHDNHLVDSGVLLVL
                     GTGGGPRIARVESVPATESAAARLGELTAKDPDGTLLVTGPWQDRDVLGQDVPSFHANP
                     GTYCTSVWLALARHWTDWRERYGTVLLCDTDPLSGATHIAVLHSDRARGAAREAR"
     gene            9947..10555
                     /gene="etmK"
     CDS             9947..10555
                     /codon_start=1
                     /gene="etmK"
                     /note="EtmK"
                     /product="short-chain acyl-CoA dehydrogenase"
                     /protein_id="QSI97710.1"
                     /transl_table=11
                     /translation="MTTTDTTLPAPVLRWLEEFAGELDACHEQAAPGGTVSSPAGWTIA
                     SVQRLPGGAPVPGTSDTLAALRDPSPADDGATQVFCDALVRLHWRLLRDVLDGAVTRLD
                     GRSSEGAPLLGRQLVRGAIADVALALSETRDLLGLPRPTAGRRRRIHRDLVGAGRTALG
                     LYGASSFAAEGPGRLLHAAELLGNTYLHPGEHEEGAGRE"
     gene            10548..11711
                     /gene="etmL"
     CDS             10548..11711
                     /codon_start=1
                     /gene="etmL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 182.9; E-value:
                     1.7e-55)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmL"
                     /product="butyryl-CoA dehydrogenase"
                     /protein_id="QSI97711.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.7e-20, bitscore:
                     62.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.6e-22, bitscore:
                     71.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPLLPRRTEVLRSHVRDAAAELRDAGLEIDRDPTAIDRWLHLP
                     AAGLMRIATLPVEYLDAPLRIGEYTYDLRSCLEHTVTIEELSYGDAGFMLACPGPLMSG
                     VAVDALGDDKQRHAYYERLSRPEPTWTFFGLTEPAKGSAATELETALTPDGDGFRLSGA
                     KRYVGNAAFAQLGVVFCRRAPGPLGIEAVLVDTRDPGFRAGLIPTVGMRGARISAITLD
                     GVRIEREQVLGYDTLKPSRRGLVGAIRTLQRFRPVLAGTALGLTRAALDHVRRERPALA
                     GAARGRLDDLRDRLEATRRQNYDIASAIDAGKVRSDRIAGVKMRAAELAERATLAAADL
                     LGPASLLEDPWLGKLYRDARAFEFMEGTGHIQRLAVFQGMAKGTFLA"
     gene            11759..12166
                     /gene="etmM"
     CDS             11759..12166
                     /NRPS_PKS="Domain: ACPS (28-68). E-value: 6.8e-10. Score:
                     30.7. Matches aSDomain: nrpspksdomains_etmM_ACPS.1"
                     /codon_start=1
                     /gene="etmM"
                     /note="EtmM"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="QSI97712.1"
                     /transl_table=11
                     /translation="MWIGIDVMTEGELGDLLGRPWFRRYVYDADELALADSFGAERARE
                     FLTGRFAGKEAALKAIGTGVGAGVTPRQVAILRADDGAPVVRLTGTAAQRARERGIGSL
                     NLSITHKKGFVVAAAIGVPARCPHPCDRPAD"
     aSDomain        11843..11962
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_etmM_ACPS.1"
                     /evalue="6.80E-10"
                     /label="etmM_ACPS.1"
                     /locus_tag="etmM"
                     /protein_end="68"
                     /protein_start="28"
                     /score="30.7"
                     /tool="antismash"
                     /translation="ADELALADSFGAERAREFLTGRFAGKEAALKAIGTGVGAG"
     gene            12242..13453
                     /gene="etmN"
     CDS             12242..13453
                     /codon_start=1
                     /gene="etmN"
                     /note="EtmN"
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="QSI97713.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTILDALLEQDPSSRVAVETL
                     ITTGLVHVAGEVTTAAYADIPALVRARILEIGYDSSKKGFDGASCGVSVSIGAQSADIA
                     QGVDTAYELRVEGDADELDRQGAGDQGLMFGYACDETPELMPLPIHLAHRLSRRLSEVR
                     KNGTVPYLRPDGKTQVTIEYQGDKAVRLDTVVVSSQHASDIDLESLLAPDIREFVVEPE
                     LKALLDEGIKLDTEGYRLLVNPTGRFEVGGPMGDAGLTGRKIIIDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLATRCEVQVAYAIGKAEPVGLFVETFGTHTVDV
                     ARIEQAITEVFDLRPAAIIRDLDLLRPIYARTAAYGHFGRELPDFTWERTDRTDALRTA
                     AGLD"
     gene            13508..14491
                     /gene="etmO"
     CDS             13508..14491
                     /codon_start=1
                     /gene="etmO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276:PfkB domain protein (Score: 96.9; E-value:
                     2.2e-29)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmO"
                     /product="adenosine kinase"
                     /protein_id="QSI97714.1"
                     /transl_table=11
                     /translation="MRIAVTGSIATDHLMVYPGRFADQLIDGHLERVSLSFLADTLEIR
                     PGGVAANIALGLGRLGLRPMLAGAVGPDFAEYRRRLEENGVDTRLVHVSDTLHTARFVC
                     TTDADQNQIATFYAGAMAQAGVIRLEAATRYAGGLDLVVVGPNDPEAMLRHTDECRALG
                     VPFAADPSQQLARIGAEEARRLIDGARYLFTNEYEAALLAQRTGWTRGEILERVGTWIV
                     TAGADGVTIAGKAEPERAVRAVPTDRAQDPTGVGDAFRAGFLAGVAWDWPPERSARLGC
                     ALATVVLESVGTQEYKLSAADLLIRIEEAYGKAAAAEIRTRLSDVL"
     gene            complement(14561..15652)
                     /gene="etmP"
     CDS             complement(14561..15652)
                     /codon_start=1
                     /gene="etmP"
                     /note="EtmP"
                     /product="bacterial conjugation repressor FinO"
                     /protein_id="QSI97715.1"
                     /transl_table=11
                     /translation="MVNAVENMLAYAAMSELSAEEDERVRFGPMPRGQDIGEDLLLGVY
                     DHVLSYHAATTLEIATALGVSSAAVRDAMRELLRLKLVRHCKEQDTFLASDPDAAQTEL
                     VLPLESAIHEKQRELIAIHHQMERFSKSFKRHQRTQRKSRLVATLENQREISLRLTDSI
                     RRSSGEILTMWPVCSYETQILEDTLRLSYDAVPRGVRLRTLYPHSARHHPSFRANLQQN
                     LESGAEVRTSDEVQHFIIIVDRETAFLPTDSSKGGTSAVTVVYEPAIVNVLCGIYRNTW
                     QSACVFDGSTPNDTSLNNVRNAILKMLACGLKDDVIARRVGISSRTLRRHIAAIMEELG
                     AESRFQAGAAAASAGLIGTPVGR"
     gene            complement(15667..16425)
                     /gene="etmQ"
     CDS             complement(15667..16425)
                     /NRPS_PKS="Domain: Thioesterase (24-245). E-value: 1e-51.
                     Score: 168.4. Matches aSDomain:
                     nrpspksdomains_etmQ_Thioesterase.1"
                     /codon_start=1
                     /gene="etmQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 219.6; E-value: 5.4e-67)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmQ"
                     /product="type II thioesterase"
                     /protein_id="QSI97716.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.5e-12, bitscore:
                     36.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIQPLDKRSDWIQRAAPRVNPGIRLVCCPYAGASASAYNALSAA
                     LPDEVEALSVQYPGRPGNRGEPPIKDVGELSDRIAEEVRPWLDRPVAVFGHSFGSVVAF
                     EVTRRLEAAGAAPVRLIVSGRRSPSDGLGSHTPRDDQEIIAELKELGGIPPRFFEKEKF
                     LEPILTVVKNDYHANSTYLASAEASVGCPISFLFADADPYLTGGGEHGWERHTTAEFQV
                     TRFSGGHFFLNEKVAEVAEEIAEILRNGVL"
     aSDomain        complement(15691..16353)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_etmQ_Thioesterase.1"
                     /evalue="1.00E-51"
                     /label="etmQ_Thioesterase.1"
                     /locus_tag="etmQ"
                     /protein_end="245"
                     /protein_start="24"
                     /score="168.4"
                     /tool="antismash"
                     /translation="RLVCCPYAGASASAYNALSAALPDEVEALSVQYPGRPGNRGEPPI
                     KDVGELSDRIAEEVRPWLDRPVAVFGHSFGSVVAFEVTRRLEAAGAAPVRLIVSGRRSP
                     SDGLGSHTPRDDQEIIAELKELGGIPPRFFEKEKFLEPILTVVKNDYHANSTYLASAEA
                     SVGCPISFLFADADPYLTGGGEHGWERHTTAEFQVTRFSGGHFFLNEKVAEVAEEIAE"
     CDS_motif       complement(16096..16161)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_etmQ_0001"
                     /evalue="9.90E-08"
                     /label="NRPS-te1"
                     /locus_tag="etmQ"
                     /protein_end="110"
                     /protein_start="88"
                     /score="24.5"
                     /tool="antismash"
                     /translation="RPVAVFGHSFGSVVAFEVTRRL"
     gene            complement(17589..18059)
                     /gene="etmR"
     CDS             complement(17589..18059)
                     /codon_start=1
                     /gene="etmR"
                     /note="EtmR"
                     /product="TetR-family transcriptional regulator"
                     /protein_id="QSI97717.1"
                     /transl_table=11
                     /translation="MGLERLLTHSGVGRASLYRHFDGKDDLVTAVLQRRDEHWRTWLRE
                     RVEAHGGAPLAVFDALAEGAQDSAFRGCAFINAMAERAKEPGSSVHRLAVEHKRKVADY
                     VCGLIKEAGHAGAPELAEQFTLLMDGAVVTAMSERSVEPFRRARQMAQRLLS"
     gene            18227..19471
                     /gene="etmS"
     CDS             18227..19471
                     /codon_start=1
                     /gene="etmS"
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 305.3; E-value: 7.7e-93)"
                     /gene_kind="transport"
                     /note="EtmS"
                     /product="MFS-type transporter"
                     /protein_id="QSI97718.1"
                     /transl_table=11
                     /translation="MSKSVPDRTSGTSEGKADGGAAAGPWRGVLVLAFGAFAIGTDEFV
                     LAGVLPELSDSLSVSITTAGQVVTVFALTCAVMAPILSTLTAAWPRHKVLKLSVLIYLL
                     GVVGTGLAPSFPVVLGAQVVAAVGAGLYIPAASVTASALMGPERRGRAIAAVTTGLTAA
                     TALGAPIGTVVGSVLDWRATMWFIALLTVLSLFGVFTLVPAVVVGAPGGLRQRLAPLGD
                     RRVVAVLAATLVAFTAAYIVYTYMAEVFAPATGGDGRKLAILMFAFGLTGMVGNFYAGT
                     LADRFGARLVVGGAVTLLAASLLVLPLATGSFPAAAVVIVVYGVAAWGITAPQQSRLIS
                     LNPESAPLLISLNAAFLYLAIALSGVIGAVGISTIGARNISLVGAAVAVLALALSELGH
                     RLAKSTRAQSAKVSA"
     gene            19513..21384
                     /gene="etmT"
     CDS             19513..21384
                     /codon_start=1
                     /gene="etmT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 631.4; E-value: 2.7e-191)"
                     /gene_kind="biosynthetic-additional"
                     /note="EtmT"
                     /product="asparagine synthetase"
                     /protein_id="QSI97719.1"
                     /sec_met_domain="GATase_7 (E-value: 1.1e-45, bitscore:
                     145.3, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.1e-89, bitscore:
                     292.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIAGWVDFERDLVKEAAAAEAMTRTMACRGPDDEGIWSAGHVM
                     LGHRRLAVIDIEGGRQPMRTPETGPDGDPLVVISYSGEVYNFKEIREELVLLGHRFRTR
                     SDTEVVLRAYLQWGSGFVDRFNGMYAFALWDTRTEELLLVRDRLGIKPLFYYPTPSGVL
                     FGSEPKAILANPLASAVMDLDGLRDALALARVPGRTPLRNLYEVRPGHIVRVSRAGIRE
                     EAYWRLETRPHTDDIPGSVAKVREILEDAVTRQMVSDVPLCTLLSGGLDSSALTALAQR
                     SLDADGGGRVRTFSVDFVGLAENFRPEPFREAPDAPFVTELARHVGTEHREILLDTARL
                     VEPGVRDAVLRAWDLPYGIGDHDPSLYLLFKAVRENSTVALSGESADEVFGGYLWFHDP
                     VASQADTYPWHAINKVPVSEQATSFLDPSLVKELSLAEYIADQYHSAANEVTHLPDDSP
                     AERRMRLASYLNITRFLQMMLDRKDRMSMATGLEVRVPLCDHRLVEYVFNAPWSVKTFD
                     GREKSLLRHATKDLLPESIVQRRKAPYPSTQDPEYDQAVNRELSRIVADPDAPALPLLN
                     TEAIRSHLAKPVDTPYSMMQRSVYTETPVRLNAWMELHGVDIQGLSA"
     misc_feature    19801..19803
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(21649..22785)
                     /codon_start=1
                     /note="Orf+1"
                     /product="calcium-independent phospholipase A2"
                     /protein_id="QSI97720.1"
                     /transl_table=11
                     /translation="MSAACESSDRSHRGRVYKETIISAIRKTLTATAVVGAVLAGSAAC
                     GTVEQLSAGKKLDRAFEKLGEKKTLSFELDLDTDAATLKALDAKSKPAPGDEMPDEAAE
                     LLSGAKITLTMESKKPLADSGEKDLVGMAMKISNPDGDLAEYRMFGDDVYLRADVDTIG
                     KLTGSPVPSADDLPPEAGAFKDVLSGKWVKFDTKEMEKAGFGGEDGEDSPAPAPSLDAK
                     TQKKLVKSLREVVAREVDLKTADGDGDTEHVTATAPFRTLLTKLLGEIRPLAKDLPPGM
                     DLPTDKDLKDAPNAKVTADFTLKNGELSEVNVDLAKLAETAKVKKLGLVLRMTDGTKPT
                     VPAGAKELDLKEIMQGLFSGPGMTEDDFGDEGFGDEDF"
     CDS             complement(22802..>24026)
                     /codon_start=2
                     /gene_functions="transport (smcogs) SMCOG1282:extracellular
                     ligand-binding receptor (Score: 130.3; E-value: 1.3e-39)"
                     /gene_kind="transport"
                     /note="Orf+2"
                     /product="periplasmic Leu/Ile/Val-binding protein"
                     /protein_id="QSI97721.1"
                     /transl_table=11
                     /translation="MAAPAGDRAPARRRVLALGSAAASVLALGGGTAAYLTVGRGSGGG
                     PPVYTLGFQADLTGAGGTDGVAQERGARLAVAHHNARAGGGFRLALDTYDDRGDPARAR
                     QAAERFTGAAVSAVLGPDTVPAALAAAPRYQSAHTAMVLISVDDPRLDDERLRTVRVTR
                     APEQFLAIPLTAYLTSVRPVDRTAVLDDRAAGRVGSELVGALTQDPPNGGTTRVYSVPA
                     GSDDFTPAVRAALAERAQAVVFTGTAAERAVRCARALAAAGFTGPRLGTWHLMRPAFLR
                     GAAAAARGWVFGAPFTDPGSVSGAFRSAHRAAYGTAPGRWAPEAYDAVGLVARALASLD
                     GPAGATPGAVAERLSDLTLQGLAKTLRFTAGSPRSIDGRQDGAYFLYRADGDAFRFLGR
                     YDRLTRRE"
ORIGIN
        1 cgggaccacc caacgagaag ggcgcatgat ggcgacgacg accgtgcaga ggaccgggca
       61 cgcgacggac gttccggaga tcgcggaccc ttccaaggtc gcgccgaagg acgcgaggga
      121 actgtcgaag ctgttcttcg accagttgac ggtgctggag gagggaaccc ccgagtacca
      181 gtacgcgcgg aacacgctga tcgagatgaa catgtccctc gtccgcttcg ccgccggccg
      241 gttccgcagc cgggggccgg aggagatgga ggacatcgtc caggtcggca tgatcggtct
      301 gatcaaggcc atcgaccggt tcgagctgtc ccgtgaggtg gagttcacct cgttcgccat
      361 cccctacatc gtgggcgaga tcaagcggtt cttccgcgac acctcctggg ccgtgcacgt
      421 cccgcgccgg cttcaggagg cccgggtgca actcgcccgc gcgaacgagg aactgcgcag
      481 ccggctgggc cggacgccga cgaccaaaga gctgtcggag ctgatgtgcc tgccggagga
      541 cgaggtcgtc gaggcgcagc tggcctccaa cgggtaccag tcggcctccc tggacgcggc
      601 gatcaacggc agtgaggacg gtgaggccgc gctggcggac ttcatcggcg ccgacgacgc
      661 cgccctcggc ctgatcgagg acttccgcgc cctcgccccg atgatcgccg agctcgacga
      721 acgcgaccgc aggatcattc actggcggtt cgtcgaggaa ctgacccagg cacagatcgg
      781 cgaacgcctc ggcgtctccc agatgcacgt ctcccgcctc ctgtcccggc tgctggcccg
      841 cctgcgcgaa ggcatgctca gcacggactg acggcccaag ggggaactcc ccccgccatc
      901 gacccggttg tgcgcccttc tcgccccgcg gtgccgagaa gggcgccggg ccttttccga
      961 ggccgtgagc acagggggag cgtctgctct caggcgatac ccaggcgagc caggagtccg
     1021 cttcccggag gcgtgggaga gcctgagccg ctgagcggcg aaccccacgc ggggtcgtgc
     1081 caggtcttcc ctccggagtg cccgagcagg cgccgggccg tgagcggagc ggtgtcccgc
     1141 ggagctccga ccgcgatcag ggcggcgccg agcgtcgccg tcgccccgcc cggcagggca
     1201 tgctcgacca gcaggggaag cagcagcaga aggcgggcag ccgggtcctc gatcccctcg
     1261 gccgcggcac cagggctgcc ggcgatgcgg accagctcac cccacctcag tgtctccccc
     1321 tccaagtccc cttgccggac ggcgaggtgc tgggcacggc cgcggcccgg aggggtgatc
     1381 aggtagtcga ctccgtagtc gtcgacgcag ttgcggtaga ccgccacgag gccgtacccg
     1441 cccgcgaccg gcacccggaa caccggccag cgtccgggat ccaggagcgc ctcggacatg
     1501 gcgtcgacat ccgctccgtc atcgccgaac cactccggtt cgacgtcccc cgcgggacca
     1561 caccggcccc acaagtggtt cggccagaag ccgggacggg ccagcaacgg ttccccggcg
     1621 accagcgggc caccgtcata tccctcgatc agcaccccac aagcctgcca tcgccgccgg
     1681 cggcgcccgt accgggcccc gcgccactct gtgccgcgca caccgggcac atccggcgcc
     1741 ggagcagggc cgcggttacg ccgaggtgac gggcaggggc gcggtgaccg gtccaggaca
     1801 gtccgctttc ggtcattgca ccgaccatgc aacgtacata tggtcatgga cggcaccgga
     1861 aatcaggtgt ctgccaagaa gtctcctgtc agcgagcact tgcttcggac ggactcggag
     1921 gacaagcggc gtggtcagcg ttctgataga tcagaatgac cgtttcctgg atattctgga
     1981 gcggctgagc tcgaagtcgg tcgaggatta ctacaatccg tacaagctgt tcgagtggcc
     2041 tgatcaactt cctcagaaca tgtggtggat gagccccgaa ctcaccacca cgtacggaac
     2101 ggccgcggcc gagcggttga cggaggaaca gctctacgcg ctgtcccgcc acgagagcat
     2161 caacttctac agcctcaacg tccacggaat ccgggaactt ctcatcgaag tgaccaggcg
     2221 catccacacc tcggggttcg agaccccgtc gcagttcttc caccacttca tcggtgagga
     2281 gaacgaacac atgtggttct tcgcggagtt ctgcctgcgc tacggcaaca agatctaccg
     2341 ccagcccgcc ggcgcgaccg cggagatacc ccgatcggac gtcgagagcc tgctggtgtt
     2401 cgcccgtatc ctcatcttcg aggaactggt cgaccacttc aactccaaga tggccctgga
     2461 cacccgcctg cacgagacga ttcgcgccat caaccggatc caccaccagg acgagtcccg
     2521 gcacatcgcc ttcggccggg aactggtctc ggccctcttc gccgaggtca agaagaactc
     2581 gaccgagcag gaactggccg atgtgtcggc ctacatcaag cggtacatga agtacagctt
     2641 cgagtctctt ttcaacccgc aggtgtaccg ggacgcgggc atcgagaagc cgcaggaact
     2701 gcgtcgggaa ctgctggagg cgcccacccg cgccgagttc gagcagagcg tcttccgcaa
     2761 gaccggcaag ttcctggaga aggtgggaat catctgatgc cgcccaccac gcagcaggac
     2821 atcggcaccg gcgacgcgct ggtcatcctc ccgccggacc agaccgacct cctcagggaa
     2881 ctcgacgccg tcttctccgg ctggggacgc gcgcagggcg cccgcgagat cctcccgccg
     2941 ccggtctacc cggtccggga cctggagaag ttcgacgtct acacgaactt cccgcacctc
     3001 gccctggtcg gggccgccct cgacctcgac acgggctccg gcaagccggc ggacggccgg
     3061 ttcgcccccg gcagcctgct cggcgcgcag ctcgggctcc cgcacgccac ctgctacggg
     3121 gcctacctgt accacgagaa cacccgcgtc cccgaccaga ccctgatcac cctggtcaac
     3181 cggtgcttcc gcaacgagga gcactacggc gggctgcgcc ggctgctgag cttccagatg
     3241 cgggagatcg tcgcgctggg cacgtacgag cacacccagg agaccatcgc ccggttcacc
     3301 gaacgcatcc tggagttctc ccgggccctg tccctcgggc tcgaaaaggt ggccgcgacc
     3361 gacccgttct tcgagaacga cggcggacgc gccctgctgg cgaaactcag ccccgtgaag
     3421 tacgagttcc aagcgggcga tctggccatc gcctcggtca acacgcaccg caacttcttc
     3481 ggggaacgct gcaacatccg gcgcgagaac agcgacgagc acgccttcac gagctgtgtc
     3541 gccttcggtc tggagcgctg gctggccgtc ctgctggacc agcacgacgg cgacgcgcac
     3601 aaggcgttgg aagccgtccg ggcggcagcc ggacaggtct cctgacatgc ttccggggcg
     3661 aatcgggatc gacctggtcc ccttcgcccg ggtgagccgg ctcctttcgc cggaggcgga
     3721 acccgtcctg ccccgcatgc tctccgggga ggaaatcggg ctctgcgtca cggacaccgg
     3781 gccggacatt ccgggaatcg ccgggagact ggccgccaag gaggccgtct tcaaactgtt
     3841 ccacgcggcg ggtcagccca tgccgtggct cggaatcgaa atcctgaagg agaacggcgg
     3901 gcggcccgtg gtgaggctca gcggccgcgc cgcacgactg gcacgggacg cccgtgtcgg
     3961 acacatcgaa gtgagcatcg cgcacgacga ccccttcgcc gtggcggtcg ccttctgcga
     4021 cacggccacg gacagggaag cacaccagct cgaatcggcc tgaaccactg aggagttgac
     4081 atggcttccg caggtatcga ggaaatacgt tcgtggatcc tgagccggca cccggaacgc
     4141 actgacgtcg cgccggacga gaacctcatc gagagccgcc tggtcgactc gctgtccttc
     4201 gtcgaactcg tctacgcgat cgagggcgcc agcggcatcg agatcgattt cgacaccatc
     4261 gacattcgcg acttccagac cctctcctcc atcgagaagg cgtttttcgc gacggtctga
     4321 cttcttaggg aggtagggga cgtggaagct gtttcgtata cggcccagtg gacggcggcc
     4381 gctcgcgccc tggagtcgga gcgcaccggg gacgccatgt tcgaggaccc gttcgcccgc
     4441 gcgctcgcgg caccgcgcgg cttcgaactg ctcgacaggt acggcggcgg cgggctggtc
     4501 ccgttcatcg cgatccgcac ccggtacttc gacgacagcg tcgagaccgt gctgcgggac
     4561 ggcgaggtca ggcaggtggt cctcgtggcc gccggaatgg acacccgggc gtaccgcctg
     4621 acgtggccgg ccggcaccac ggtgtacgag atcgaccacg aggccctgat ggaggagaag
     4681 cgcgaccgcc tcgcacggct gggcgcgcgg gccggtgtcg aacgcgtgga ggtcaaggcc
     4741 gacctcgccg gggactggct gcccacgctg aagcaggccg gcttcgaccc ggccaggccg
     4801 acgctgtgga tcgccgaggg actgatgttc ttcctcaccg aggaccaggt cgtccacctg
     4861 ctgcgcaccc tgggctcggc ctccgccccc ggcagctggc tggcggtgga tttcgtgagc
     4921 aaggcgctgc tgcgcagtcc gttctcccag tcgttcctca aggggctgaa ggaggacggc
     4981 acaccgtggc tgttcgggac cgacgaaccg gaggacttcc tggccgcctc gggctggaag
     5041 gtgcgcgatc tgcgcgagcc cggcgacccc ggcgccggtg agggccgctg gccgtacgag
     5101 gtgcagcccc gcgaccgccg gggcgtgtcc cgcagctggc tcgtccgggc cgagtacgcg
     5161 ggcagctgag gaggccgggt gagcaccgcg acgacgctgg agaggatcga gtcgttcctc
     5221 cccgaacgca gcgtcaggat cgacgacgtg gccggcagcc tgggactcag acgcgccgag
     5281 gtgggcgtct tccgcaagat ctacggactg gaccggctcc gcttcgaccc ggacaccggc
     5341 ctgttcgacc tggtgctccc ggcggcgcgc cgggcgctgg acgcgcttcc cgaaggacgc
     5401 cgggtcgagt acgtcatcta cgcgcacacc gtgcaggccg tcgccccgcc gcacgtcgac
     5461 accgccgcga cgatccgcga cggcctcgga ctgcacgacg cggaggcctt cgcgctgacc
     5521 caccaggcct gtgtcagcag cctgggcgcg atcgacctgg cgggcgaact gctgcgcgcc
     5581 gaggcccccg agggcgcgta cgcgctgatg gtcaccggcg agcgggcgta ctcgcccaag
     5641 gtgcagctca tccccaacag cgccatcatg gccgacgcgg cggccgcctg cctggtgacc
     5701 gtgggcggcc ccggcgacga ggtgctgtcc ttcgtgaccc gcaccctcgg cgagtacgcc
     5761 gccggcctgg agatgacgag ggaggagaca caggggttcg ggcaggtcta cggcaccgtg
     5821 ctcggcgagg tgatcaacga ggccgtggac gccgccgcgc tctccttcga cgacgtcgac
     5881 ctggtgatcc cgcacaacgt caacatggtc tcctggcgcc agaccatcaa ggagatgggg
     5941 gccgatccgg agaagttctt cctggacaac gtggcgcagt acagccacac ctacgcctcc
     6001 gacgtcttcg tcaactacac gacgctgcgc gaccgggacc gcctgaccga cggccggtac
     6061 tacgtcctgg tctccgtcgg cctcggcgcc accttcggcg ccatggtgat caggcacagg
     6121 aagcggtgag cgcgatgtcc ttcgacgacg gttacaccgc gggcctgaag caggcgctca
     6181 ccggcgaccg ggacgcccgg ttcgtatggc tgtgcaactt cgaggtggag aaccagtggg
     6241 cgcgctccta caccggtctc ccggcggcgc ggggctcggc gacggccgcc accgtgcagc
     6301 gcatggagga gctgggcgcc ctgctggccg agccggccga ctacctcctc ctggaccgcc
     6361 ccctggacga gggctaccgc agctacgccg agaagacggg cctgggagcc cccgtcgagc
     6421 tggtcaccgc cgcgcccgcc gcggacggcg gcaccggcgc ggccgtgctc gactccccgg
     6481 aactcctgga gcggctgcgc cggatcgccc gggacggcgc ctacctgatg cccatgggca
     6541 actccgtcca ggaggagcgc atcgccgaac tgaccgggct gcgcctcgcg gtgcccgacg
     6601 ccgccacctg cgaacgcgtc aacagcaaga tctacagccg gcgggcggcc gaggaactgg
     6661 ggctgcgcac gatccccggc ttctgctgcg agacggtggg gcagctgcgg cgcgccctgg
     6721 acgaagggct gcgcgacgac cggccggtca tcgtgaagga cgcctacgga gtctcgggca
     6781 agggcctgct gatcctggac agccgcagga aggccgaccg gctgctccgc atggtcgagc
     6841 gcagggccgc gaaccgcggt gacgatgcgc tgcacgtcgt ggtcgagacg ttcctgccca
     6901 aacgcttcga cctcaactac cagttcaccg tcgaccgccg cgggcgggtg cgcctggact
     6961 tcgtcaagca ggccctcacg tccggcgggg tgcacctcgg ccatgtcatg cccgccgacc
     7021 tcacccccgc ccagcaggac gaactggccg ccgcagccgt ggccctgggc gcgcgcctgt
     7081 acgcggacgg tttcttcggc gtcgtcggcg tggacgccct gctgggcgcc gacgaccggg
     7141 tctacccggt cctggagatc aacgcccggc tgaacatgtc cagttaccag gggagggtca
     7201 ccgagcgctt cggccggccc cggggagccg ccctcgccag gcactacccg ctgcggctgg
     7261 ccgaacccct cccgttcgag gcggtcaccg acgcgctcgg cgacctcgcc gaaccgcccc
     7321 acgaccggga cgggctcgtc atcacctgct tcgggacggt caacgcccag gccggcgacg
     7381 cgctcgccgg cgtaccacgg ggcacgccgg ccccccactt caacggccgg ctctacacca
     7441 tgctgttcgc cgggaaccgc gagggactcg acgtgctgga ccgccgggtc gaggccgcgc
     7501 tcgaccgact gaacacagcc gggaggacgc catgagcagt cgggaactcc atgtgcaggg
     7561 cataccggtg tcggagatcg cggaggagtt cggcaccccg ctgttcctct acgacgccga
     7621 cgtgctgcac tccgtctaca cctccctgag ggagcggctg caccccgccg tcgacatctt
     7681 ctactccctc aaggccaacc ccaacatcag cgtgtgcggc tacctcgcct cgctgggcgc
     7741 cggcgccgag atctcctcga tggtcgagct gatgacggtg cggcgggccg gcgtcgcgcc
     7801 tgagaacgtc atcttcctgg ggccgggcaa gacccgggcc gagctggagg cgtgcgtcac
     7861 cgccggcatc cacgcggtgg tgtgcgagtc cctggaggag gtcgccctcc tggaggagat
     7921 cgccgccggg ctgggacgcg acgacgtcac ggtgctgctg cgcatcaacc cggacttcca
     7981 caccaagggc tccggcctgg ccatgggcgg caagccacgg cagttcggca tcgacgcgga
     8041 cacgctgcgc cgctcacggg aacagctcgc cgcactgcgc cgggtgcggg tgcgcggctt
     8101 ccacgcgtac atggggacgc gcttcctgaa cgccgacgac ctcgtgcaca acacccgcga
     8161 gatcctcgcc ctcgcggccg acctgtcgga gcggctgggc atcgtccccg agaccgtgga
     8221 cttcggcggc ggcttcggtg tcgcctactt cgacaacgag aagagcctcg acatcgagac
     8281 cacggtcgcc ggcatcaacg aggccgtcgc ctccttcacc gcgaagtacc cccgctgccg
     8341 cctgatcaac gagctggggc gctacctcgt cgccgcctgc ggcacctacg tggtgcgcgc
     8401 cctgtacgtc aaggagtccc tgggcgagaa gttcgtgatc gccgacggag gcaccaacca
     8461 ccacatggcc gcggtgggca tcggcagctt cgtcaagcgc aacttcccga tccggtcgct
     8521 gagccggcac ggcgaggagg cggcggacac ctacacggtc accgggccgc tgtgcacgcc
     8581 caacgacgtc atcggcaaga aggtccagct gccgccggtc gcacccggcg acctcatcgg
     8641 cgtcgaactc tccggcgcct acggaccgac ggcctcaccc gggctcttcc tcagccacgg
     8701 attccccgcc gaggtcctcg tgcacggcgg cacggcccac ctcgtccgcg aacgggaccg
     8761 caaggaggac ctgctcgaca agcagcgcct cgtggacttc acccgccact gaaggaaccc
     8821 ggcaccgaag gagaacatcg gcaatggaac gtcacgacgt ggtcaacgcc gtcgagaagg
     8881 cgctcagcga ggtgctggag cagcccgtca ccggcctgac cgaagaggtc cggctcttcg
     8941 aggacctgca cctggactcc acctcggtcc tggagatgct gatggccctg gaggacgcca
     9001 tcgacatctc cgtcgacccg gagaacctcg acatggacga cttcaagtcg gtcggcacgc
     9061 tcaccgatta cgtcctgtcc cagcagacca ccagcggagt atgaggcgga tcgcacatgc
     9121 cggccctcct tgccgcctgc ggggtggtgg caccgccccg caggtccccc gaaccgaccc
     9181 tgtccaacct ctcctactac cgtgacctgg tcgagccctt cggcctggag gtggacgaga
     9241 cgctgctgcg ctccgcgccc cacgtcggcc accgcgacct ggtcgaccgg ctggtggccg
     9301 cctcggggac cgacggcagc gaccccgacc tggtgatcgt gacccacgcg ctgccggaca
     9361 tcaccccgtt caccgccatg gcgccctacc tggaccggct cctgggcggc cgggccgtca
     9421 acttcggcat ccaccagcag gggctggccg cgccgttcac cgcgctgcgc gccgtctcgg
     9481 ccttccagcg ggcgggccgc tcccagcggg cggtgctcgc cgtcctggaa cagaccaccc
     9541 tgcccacgcg cttccccctg gtccacgaca accacctggt cgactccggg gtcctcctgg
     9601 tcctcggcac cggcggcggg ccgcggatcg cccgggtgga gtccgtcccg gcgaccgagt
     9661 ccgccgccgc ccggctcggc gagctgaccg cgaaggaccc ggacggcacc ctgctcgtca
     9721 ccggcccctg gcaggaccgt gacgtgctcg gccaggacgt cccctccttc cacgccaatc
     9781 ccggcaccta ctgcaccagc gtctggctgg ccctggcccg gcactggacc gactggcggg
     9841 agcggtacgg cacggtgctg ctgtgcgaca ccgacccgct ctccggcgcc acccacatcg
     9901 ccgtactgca ctccgaccgg gcccggggcg ccgcgcggga ggcgcgatga cgacgacgga
     9961 caccaccctc cccgcccccg tcctgcggtg gctcgaggag ttcgccgggg agctggacgc
    10021 gtgccacgaa caggccgcac cgggcggcac ggtgtcctcc ccggccggct ggaccatcgc
    10081 ctccgtacag cgcctgcccg gcggcgcccc ggtccccggc acctcggaca ccctcgccgc
    10141 gctgcgggac ccgtcgccgg ccgacgacgg ggcgacacag gtcttctgcg acgcgctggt
    10201 gcggctgcac tggcggctgc tgcgcgatgt cctcgacggc gccgtcaccc gcctcgacgg
    10261 gcgctcctcg gaaggagccc cgctgctcgg ccggcagctc gtccggggcg cgatcgccga
    10321 cgtggccctc gcgctctccg agacccggga cctcctcggc ctgccccggc ccaccgccgg
    10381 gcgccgccgc cggatccacc gcgacctggt gggcgccggc cgcaccgcgc tcggactgta
    10441 cggcgcgagc agcttcgcgg ccgagggccc cggccggctc ctccacgcgg ccgaactgct
    10501 gggcaacacc tacctgcacc ccggagagca cgaggaggga gccggccgtg agtgagcccc
    10561 tgctgccccg ccggacggag gtgctgcgct cccacgtcag ggacgcggcc gcggaactgc
    10621 gggacgccgg cctggagatc gaccgcgacc ccacggccat cgaccggtgg ctccacctgc
    10681 ccgcggccgg cctcatgcgc atcgccaccc ttcccgtcga gtacctggac gccccgctgc
    10741 gcatcggcga gtacacctac gacctgcgct cctgtctgga gcacaccgtc accatcgagg
    10801 aactgagcta cggcgacgcc ggcttcatgc tcgcctgccc cggcccgctg atgtccgggg
    10861 tcgcggtgga cgcgctcggc gacgacaagc agcggcacgc ctactacgag cggctgagcc
    10921 gccccgagcc gacctggacg ttcttcggcc tcaccgagcc cgcgaaggga tcggcggcca
    10981 ccgagctgga gaccgccctg acccccgacg gcgacggctt ccgcctcagc ggtgccaagc
    11041 gctacgtcgg caacgccgcc ttcgcccagc tgggcgtggt gttctgccgc cgggcgcccg
    11101 gaccgctggg catcgaggcg gtgctcgtcg acacccgcga ccccggcttc cgggccgggc
    11161 tcatcccgac cgtcggcatg cgcggggcgc gcatctcggc catcacgctc gacggcgtgc
    11221 ggatcgagcg ggagcaggtc ctcggctacg acacgctcaa gcccagccgc cgcgggctgg
    11281 tgggagccat ccgcaccctc cagcgcttcc gcccggtcct cgccggcacc gcgctgggcc
    11341 tgacccgcgc cgccttggac cacgtccgcc gcgagcgccc ggcactcgcc ggagcggccc
    11401 gcggccggct ggacgacctg cgggaccggc tcgaggccac ccggcggcag aactacgaca
    11461 tcgcgtccgc gatcgacgcc gggaaggtgc ggtccgaccg catcgccggc gtcaagatgc
    11521 gcgccgccga gctggccgaa cgcgccaccc tcgccgcggc cgacctcctc ggccccgcat
    11581 ccctcctgga agacccgtgg ctgggcaagc tgtaccgcga cgcgcgcgcc ttcgagttca
    11641 tggagggcac cggccacatc cagcggctcg cggtgttcca aggcatggcc aaaggcactt
    11701 tcctcgcatg accccggccc cccgcgccag gacccgggaa ggagacaggg agcgagccat
    11761 gtggatcggc atcgacgtca tgaccgaggg cgaactcggc gacctgctcg gccggccctg
    11821 gttccgccgt tacgtctacg acgccgacga actggccctc gcggactcct tcggggcgga
    11881 acgcgcccgg gagttcctca ccggccgctt cgccggcaag gaggccgccc tcaaggccat
    11941 cggcaccggt gtcggggccg gggtgacccc ccggcaggtg gccatcctgc gcgcggacga
    12001 cggagccccc gtggtacggc tgacggggac cgccgcccag cgcgcgcggg aacggggcat
    12061 cggctccctc aacctgtcca tcacccacaa gaagggcttc gtcgtcgccg cggccatcgg
    12121 ggtgcccgcc cggtgcccgc acccctgcga ccggcccgcc gactgacccc gccccgcccg
    12181 ccgtgcccgt atccgccgcc ggtgcgcccc gcgcaccggc cgacccctct cagggagcgc
    12241 tgtgtcccgt cgtctgttca cctccgagtc cgtcaccgag ggccaccccg acaagatcgc
    12301 cgatcagatc agcgacacca tcctcgacgc cctgctggaa caggacccgt cctcccgcgt
    12361 ggcggtggag acgctgatca ccaccggcct ggtccacgtg gccggggagg tcaccaccgc
    12421 cgcgtacgcg gacatccccg cgctggtgcg ggccaggatc ctggagatcg gctacgactc
    12481 ctccaagaag ggcttcgacg gcgcctcgtg cggggtgtcg gtgtccatcg gcgcccagtc
    12541 ggccgacatc gcccaggggg tggacaccgc ctacgagctg cgggtggagg gggacgccga
    12601 cgaactggac cggcagggcg ccggtgacca ggggctgatg ttcggctacg cctgcgacga
    12661 gaccccggag ctgatgccgc tgccgatcca cctggcccac cggctgtcac ggcgcctgag
    12721 cgaggtccgc aagaacggga ccgtccccta cctgcgtccg gacggcaaga cccaggtcac
    12781 catcgagtac cagggtgaca aggccgtccg gctggacacg gtggtggtct cctcccagca
    12841 cgcctcggac atcgacctgg agtcgctgct cgcccccgac atccgcgagt tcgtcgtgga
    12901 gccggagctg aaggccctgc tggacgaggg catcaagctc gacaccgagg gctaccgcct
    12961 gctggtcaat ccgaccggcc gcttcgaggt cggcggcccg atgggcgacg ccggtctgac
    13021 cggccgcaag atcatcatcg acacgtacgg cggcatggcc cgtcacggcg gcggcgcctt
    13081 ctcgggcaag gacccctcca aggtggaccg ctcggccgcg tacgccatgc ggtgggtcgc
    13141 caagaacgtc gtggcggccg ggctggcgac ccgctgcgag gtccaggtcg cctacgccat
    13201 cggcaaggcc gagccggtcg ggctgttcgt ggagaccttc ggcacccaca ccgtggacgt
    13261 ggcgcggatc gagcaggcca tcaccgaggt gttcgacctg cggcccgccg cgatcatccg
    13321 tgacctggac ctgctccgcc cgatctacgc ccggacggcc gcctacggtc acttcggccg
    13381 ggaactgccc gacttcacct gggagcgcac cgaccgcacc gacgccctcc gcaccgccgc
    13441 cggcctggac tgacgcgaac cgccccccgg cactcccgtg cccgggcggg ccgagggagg
    13501 aagcaccgtg cgtatcgccg tgaccggatc catcgccacc gaccatctga tggtctaccc
    13561 cggacggttc gccgaccagc tgatcgacgg ccacctggag cgggtctcgc tgtccttcct
    13621 ggcggacacc ctggagatca ggcccggggg agtggccgcg aacatcgccc tggggctggg
    13681 acgcctgggc ctgcgtccga tgctggcggg agccgtgggc cccgacttcg ccgagtaccg
    13741 ccgccggctg gaggagaacg gcgtggacac ccggctcgtc cacgtgagcg acaccctgca
    13801 caccgcccgc ttcgtgtgca cgacggacgc cgaccagaac cagatcgcca ccttctacgc
    13861 gggcgccatg gcacaggccg gcgtcatccg gctggaagcg gccacccggt acgccggcgg
    13921 gctggacctg gtggtggtgg gccccaacga cccggaggcg atgctccgcc acaccgacga
    13981 gtgccgcgcg ctcggcgtcc cgttcgccgc cgacccctcc cagcagctcg cccgcatcgg
    14041 ggccgaggag gccaggcggc tgatcgacgg cgcccgctat ctgttcacca acgagtacga
    14101 ggccgccctg ctcgcgcagc ggaccggctg gacgcgtggc gagatcctcg aacgcgtcgg
    14161 cacctggatc gtcacggccg gcgccgacgg tgtgaccatc gccgggaagg cggagcccga
    14221 gcgcgcggtc cgggcggtgc cgacggaccg ggcccaggac cccaccggag tcggcgacgc
    14281 cttccgggcc ggtttcctcg ccggcgtggc ctgggactgg ccgccggagc gctcggcccg
    14341 gctcggctgc gcgctggcca ccgtcgtcct ggagtcggtc ggtacgcagg agtacaagct
    14401 ctccgcggcc gacctgctga tcaggatcga ggaggcctac ggcaaggccg cggcggccga
    14461 gatccgtacg cggctgtcgg acgtgctctg acggccccgg ggcccggtgc aggggggcca
    14521 cccccgtgcc gggccccgcg gcgccgcagg gatgccgctg tcacctgccg acgggggtcc
    14581 cgatgaggcc cgcgctcgcc gccgccgcgc cggcctggaa gcggctctcc gcccccagct
    14641 cctccatgat cgcggcgatg tggcggcgca gggtgcgcga ggagatcccc acccggcggg
    14701 cgatgacatc gtccttgaga ccgcaggcga gcatcttcag gatcgcgttc cggacgttgt
    14761 tgagcgaggt gtcgttgggg gtgctgccgt cgaagacgca ggccgactgc caggtgttcc
    14821 ggtagatgcc gcacagcacg ttcacgatcg ccggttcgta gacgacggtg accgcggagg
    14881 tgcctccctt ggaggagtcg gtgggcagga acgccgtctc ccggtcgacg atgatgatga
    14941 agtgctgcac ctcgtccgac gtccggacct ccgcccccga ctccaggttc tgctggaggt
    15001 tcgcccggaa actgggatgg tgcctggccg agtgggggta cagggtgcgc agtcgcaccc
    15061 cgcgcgggac cgcgtcgtag gagagccgga gggtgtcctc caggatctgt gtctcatagc
    15121 tgcagaccgg ccacatcgtg aggatctccc cggaggaccg gcggatcgag tccgtcagcc
    15181 gcagggagat ctcgcgctgg ttctccagcg tcgccaccag ccgactcttc cgctgggtgc
    15241 gctggtgccg cttgaaggac ttggagaaac gttccatctg gtggtggatg gcgatcagtt
    15301 cgcgctgttt ttcgtgtatg gcggattcga gcggcagaac gagttccgtc tgggcggcat
    15361 cggggtcgga ggccaggaag gtgtcctgct ccttgcagtg tctgacgagt ttcagacgca
    15421 acagttcccg catggcgtcc ctgacggcgg cgctcgacac cccgagcgcc gtggcgattt
    15481 ccagtgtggt cgccgcgtga taggacagta cgtgatcgta cacaccgaga agcaggtcct
    15541 cgccgatgtc ctggccgcgt ggcatcggcc cgaagcggac tctctcgtct tcctccgccg
    15601 acagctcgga cattgctgcg tacgcgagca tgttctccac tgcgttcacc atcccgagtc
    15661 agacggtcaa agaactccgt tgcggaggat ctcggcgatc tcctcggcga cctccgcgac
    15721 tttttcgttc aggaagaaat ggccaccgga gaagcgggtg acctgaaatt ctgccgtggt
    15781 gtgccgctcc cagccgtgct ccccgcctcc ggtcagatac ggatccgcgt cggcgaacag
    15841 gaaggatatg gggcagccga ccgacgcctc tgcggatgcg agatacgtgg aattggcgtg
    15901 gtagtcgttc ttcacgaccg tgaggatcgg ctccaggaat ttctctttct cgaagaaccg
    15961 gggaggaatg ccgcccagct ccttgagttc cgcgatgatc tcctggtcgt cgcgcggtgt
    16021 gtggctgccg agcccgtcgg agggggagcg gcggccggac acgatgagcc gcacgggggc
    16081 ggcgccggcg gcctccaggc gccgggtgac ctcgaaggcc accaccgagc cgaaactgtg
    16141 gccgaagacg gccaccggcc tgtcgagcca ggggcggacc tcttcggcga tgcggtcgga
    16201 gagttcgccg acgtccttga tcggtggctc gccgcggttc cccgggcggc ccgggtactg
    16261 gacggagagc gcctccacct cgtcgggcag ggccgcggac agggcgttgt aggcactggc
    16321 ggaggcgccg gcgtagggac agcacaccag acggattccg gggttcaccc ggggcgccgc
    16381 tctctggatc caatcgcttc tcttgtcgag gggttggatg gccatgtcac cttccgtgtg
    16441 tccccggggg gagcgtaccg gatcggccgc aggcattgcc tgggaatggc gcaccactgg
    16501 tgaggcgctg cggtggcgct cttttttctc gcttctccgt caaatcatct gccatgtaat
    16561 gcggagagcc gatcgatccg ttcgttccgg cctcggactg gcggattaaa agcttccgtt
    16621 acggtcacgc tactgacagt tgcgtcatat gtcaacggtg tttctggcgg tcgccgacgg
    16681 tcgatgtgcg gcaggtcaca gcgcttttcg tgaagcgcat gaatacaaca gcagacgaat
    16741 aggaagaatt gaggaccggc ttgtccgtcg gcccgcacac cccaaaaaaa gaggttgctc
    16801 gccttgcaat agcgtagggt gaccgggcta cgccaaagga tacggtgtca cacctttaga
    16861 cgtggctgcc ggacagccct gagggctgtt tccggccaat gttccgaacg tcctcccgcg
    16921 caggccggtc cggttcaccg tgacggacgg gaaatgtgtg acgtcagtgg caggagagcg
    16981 agacggggga cggccgacat cggtggccgt cggcatgccc ccggggtggt ctcgcgtggg
    17041 cgcccgggac cggcgggacg gtgcggccgg cgggggccga gggggtgagg gcgaaggtcc
    17101 gtgccctgtg cggggtgccc gccggtgccg cggcggcgga caggggcggt ctcgtgaccg
    17161 gcgtccgtcg ccggaaccgc cgcgcggcca gggccgccgg gccacaggga gcgcctggac
    17221 agggtgcttc ggtggtccgc agggttctgg tcatcagcgc acccgcacct cccacgatcc
    17281 cggccgccgt ggcggctgtc gtcaaccccc ttcgatgagc atcgaccact tcgatgcgta
    17341 tcaaaccgag agcggggtat gacacaggtc agggaacgcg gccggctgcc gcaaccgcag
    17401 gctgccgcag ccgcacacgg agcgcggcgg caccggagcg cttccgtccc cgtgcgtcac
    17461 gcacggagct cgaccggcgc ttttccaggc ctgctcgact tgatccgggg agccgggccc
    17521 gccgctccgg acacatgcag ggatggtgtg cgcacggacg catgagcaag gggtgaggcg
    17581 gacacgggtc aggacagcag ccgctgcgcc atctgccgcg cccgccggaa aggctcgacg
    17641 ctgcgctcgc tcatcgcggt gaccacggcc ccgtccatca gcagcgtgaa ctgctccgcc
    17701 agctccggcg ccccggcgtg gccggcctcc ttgatcaggc cgcacacata gtcggcgacc
    17761 ttgcgcttgt gctcgacggc gagccggtgg acgctgctgc cgggttcctt cgccctctcc
    17821 gccatggcgt tgatgaaggc gcagccgcgg aacgcgctgt cctgcgcccc ctcggccagg
    17881 gcgtcgaaga cggccagggg tgcgccgccg tgggcctcga cgcgctctcg cagccacgtc
    17941 ctccagtgtt cgtcccggcg ctgcaggacc gcggtcacca gatcgtcctt gccgtcgaag
    18001 tgtcggtaca gggaggcgcg cccgacgccg gagtgggtca ggaggcgctc caggcccact
    18061 ccgttgatgc cctcctcgta gaagagctca tcggctgcct gtagtaggcg gtcacgtgcg
    18121 cgagtcggca tgtggccaga gtagtcgccc ttgacgctaa acggtaccga ccgataccgt
    18181 ccgccaagat ggtaccgatc ggtaccgaaa tcgaggaggg ttcatagtga gtaagtccgt
    18241 cccggaccgg acgagcggga cgtctgaggg gaaggccgac gggggagcgg ccgccgggcc
    18301 gtggcgggga gtcctcgtcc tggcgttcgg cgccttcgcc atcggcacgg acgagttcgt
    18361 gctcgccggc gtactgcccg agttgagcga ctccctgtcc gtcagcatca ccaccgccgg
    18421 gcaggtggtc accgtgttcg cgctgacctg cgcggtcatg gcgccgatcc tgtccacgct
    18481 caccgccgcc tggccgcgcc acaaggtgct caagctgtcc gtgctgatct atctgctcgg
    18541 cgtcgtgggg accggactgg cgccgtcgtt ccccgtggtc ctgggcgccc aggtcgtcgc
    18601 cgccgtcggc gccggcctct acatcccggc ggccagtgtc accgcctccg cgctgatggg
    18661 gcccgaacgc cggggccggg ccatcgcggc cgtcaccacc gggctcaccg ccgcaaccgc
    18721 gctcggcgcg ccgatcggga ccgtcgtggg cagcgtcctc gactggcggg ccacgatgtg
    18781 gttcatcgcc ctcctcaccg tgctgagcct gttcggcgtg ttcaccctcg tgccggcggt
    18841 ggtcgtgggc gctccgggcg ggctgcgcca gcgcctcgcg ccgctcggcg accgtcgcgt
    18901 cgtcgccgtg ctcgccgcga cgctcgtcgc cttcaccgcg gcgtacatcg tctacaccta
    18961 catggccgag gtgttcgccc ccgccaccgg cggcgacggc aggaaactgg ccatcctgat
    19021 gttcgccttc ggtctgacgg gcatggtcgg caacttctac gccgggacac tggccgaccg
    19081 gttcggggcc cgtctggtgg tgggcggcgc ggtcacgctg ctggcggcca gcctcctcgt
    19141 gctgccgctc gccaccggct cgttccccgc ggccgccgtc gtcatcgtgg tgtacggcgt
    19201 cgcggcctgg ggcatcaccg cgccgcagca gtcacgcctg atcagcctca acccggagtc
    19261 ggctcccctg ctgatctccc tcaacgccgc gttcctctac ctcgccatcg ccctctccgg
    19321 cgtcatcggc gcggtgggca tcagcaccat cggggcccgg aacatcagcc tggtcggcgc
    19381 cgcggtggcc gtgctcgcgc tggcgctgtc cgaactggga caccggctgg ccaagagcac
    19441 gcgggcgcag tcggccaagg tcagcgcgta gtcggcacac atgtcattca acccgtagtg
    19501 aagggcgttc ctatgtgcgg aatcgctgga tgggtggact tcgaacgcga cctcgtcaag
    19561 gaggcggccg cggcagaggc catgaccagg acgatggcct gccgtggccc cgacgacgag
    19621 gggatctgga gcgccgggca cgtgatgctc ggacaccgcc ggctcgcggt gatcgacatc
    19681 gagggcggcc ggcagccgat gcgcaccccg gagaccggtc cggacggcga tccgctggtg
    19741 gtgatcagct acagcggcga ggtgtacaac ttcaaggaga tccgcgagga actcgtcctc
    19801 ttaggacacc gcttccgcac caggagcgac accgaggtcg tcctccgtgc ctacctccag
    19861 tggggcagcg ggttcgtcga ccggttcaac gggatgtacg ccttcgccct gtgggacacc
    19921 cggaccgagg aactgctcct ggtccgggac cgcctcggga tcaagccgct cttctactac
    19981 cccaccccgt ccggggtgct gttcgggtcg gagcccaagg cgatcctggc gaatccgctc
    20041 gccagcgcgg tcatggacct cgacggcctg cgcgacgcgc tcgcgctggc ccgggtaccc
    20101 ggacggaccc cgctgcggaa cctgtacgag gtgcggccgg gacacatcgt ccgcgtcagc
    20161 cgcgcgggca tacgcgagga ggcgtactgg agactcgaga cccggccgca caccgacgac
    20221 atccccggga gcgtcgccaa ggtacgggag atactggagg acgcggtcac ccggcagatg
    20281 gtctccgacg tgccgctgtg cacgctcctg tcgggcggcc tggactccag cgcgctgacc
    20341 gcgctcgccc agcgttcgct ggacgccgac ggcgggggac gggtccgcac cttctccgtg
    20401 gacttcgtcg gcctcgccga gaacttccgg cccgagccgt tccgcgaggc gcccgacgcg
    20461 ccgttcgtca ccgaactcgc ccggcacgtg ggcaccgagc accgcgagat cctgctcgac
    20521 accgcccggc tcgtcgaacc gggcgtacgc gacgccgtgc tgcgggcctg ggacctcccc
    20581 tacgggatcg gggaccacga cccctccctc tacctgctgt tcaaggcggt ccgcgagaac
    20641 tcgaccgtgg cgctgtcggg agagtccgcc gacgaggtct tcgggggcta cctgtggttc
    20701 cacgacccgg tcgcctcgca ggccgacacc tacccgtggc acgcgatcaa caaggttccg
    20761 gtgagcgagc aggccaccag cttcctggac ccgtccctgg tcaaggagtt gagcctcgcc
    20821 gagtacatcg ccgaccagta ccacagcgcc gcgaacgagg tcacccacct tcccgacgac
    20881 agcccggccg agcggcggat gcggctcgcc agctacctca acatcacccg cttcctgcag
    20941 atgatgctgg accgcaagga ccggatgagc atggcgaccg gcctggaggt cagggtcccg
    21001 ttgtgcgacc accggctcgt cgagtacgtc ttcaacgcac cctggtcggt gaagacgttc
    21061 gacgggcggg agaagagtct cctgcggcac gcgaccaagg acctgctgcc cgagtcgatc
    21121 gtccagcggc gcaaggcgcc ctatccctcg acccaggacc cggagtacga ccaggcggtc
    21181 aaccgtgagc tgagccggat cgtcgccgac ccggacgcgc cggcgctgcc gctgctgaac
    21241 accgaggcga tccgttccca cctcgccaag ccggtcgaca ccccgtactc gatgatgcag
    21301 cgctccgtct acaccgagac tcccgtccgg ctgaacgcct ggatggaact ccacggcgtc
    21361 gacatccagg gcctgtcggc ctgaggccgt cccgccccgc ccggatccac ggccgccgcc
    21421 ggtcaccggt accggcggcg gccgcgcacg ctgccccgcc ggtgtgtgtg ccgtgcaccc
    21481 gggcgccgag cgcgcggagt cgtcagcggg atcccgttcg cgtccgtcgg ccccgtgcgg
    21541 ggaccggtcc ggtgcctccc gacgcgggcc ggaagctgcc ccccgcggtg tgcggtccgg
    21601 cggggaggcg gccggcgggt gctcaccgtt cgttcacggt cggcgtgatc agaagtcctc
    21661 gtcgccgaag ccctcgtcgc cgaagtcgtc ctcggtcatc cccggtccgg agaagaggcc
    21721 ctgcatgatt tccttcaggt ccagctcctt ggcgccggcc ggaacggtgg gcttggtgcc
    21781 gtcggtcatc cgcaggacca ggcccagctt cttgaccttg gcggtctcgg ccagcttggc
    21841 gaggtccacg ttcacctcgg acagctcacc gttcttgagc gtgaagtcag ccgtcacctt
    21901 ggcgttcggg gcgtccttca ggtccttgtc cgtcggcagg tccatgcccg gcggcaggtc
    21961 cttcgccagc gggcggatct cgccgagcag cttggtgagc agcgtgcgga agggagccgt
    22021 ggcggtgacg tgctcggtgt cgccgtcccc gtcggccgtc ttgaggtcca cctcgcgggc
    22081 gacgacctcg cgcagcgact tcaccagctt cttctgcgtc ttggcgtcca gggacggagc
    22141 gggcgcgggg ctgtcctcgc cgtcctcgcc cccgaagccg gccttctcca tctccttggt
    22201 gtcgaacttc acccacttgc cggacaggac gtccttgaag gccccggcct ccggcggcag
    22261 gtcgtcggcg gacggcacgg ggctgcccgt cagcttgccg atggtgtcga cgtcggcacg
    22321 gaggtagacg tcgtcaccga acatccggta ctcggcgagg tcgccgtccg ggttgctgat
    22381 cttcatggcc atgccgacga gatccttctc gccggagtcg gcgagcggct tcttcgactc
    22441 catggtgagc gtgatcttcg cgccgctgag cagttcggcg gcctcgtccg gcatctcgtc
    22501 gccgggcgcg ggcttcgact tggcgtccag cgccttcagc gtcgcggcgt cggtgtccag
    22561 gtccagttcg aaggagagcg tcttcttctc gccgagcttc tcgaaggcgc ggtcgagctt
    22621 cttgccggcg gagagctgct ccaccgtccc gcaggccgcc gagcccgcga gaacggcgcc
    22681 gacgacggcg gtggcggtca gggtcttgcg tatggcgctg atgatggtct ccttgtagac
    22741 gcgaccacgg tgtgatcgat cagaagactc acaagccgcc gacaaggttg cacgccattt
    22801 ttcattcgcg tcgggtgagc cggtcgtagc gcccgaggaa ccggaaggcg tcgccgtccg
    22861 ctcggtacag gaagtacgcc ccgtcctgcc gcccgtcgat gctccggggg ctgccggcgg
    22921 tgaagcgcag ggtcttggcg agtccctgga gggtgaggtc cgacagccgc tcggcgaccg
    22981 ccccgggggt ggcgccggcc gggccgtcca gcgaggcgag ggcccgggcg accagtccca
    23041 ccgcgtcgta cgcctccggg gcccagcggc cgggcgcggt gccgtaggcc gcgcggtggg
    23101 cggaccggaa ggcgccggac acgctgcccg ggtcggtgaa cggggcgccg aacacccagc
    23161 cccgcgccgc cgcggcggcc ccccgcagga aggccggccg catgaggtgc caggtgccga
    23221 ggcgtggccc ggtgaagccg gccgccgcga gggcgcgggc gcagcgcacg gcgcgttccg
    23281 ccgctgtccc cgtgaagacg acggcctggg cccgttcggc gagcgcggcg cggacggcgg
    23341 gggtgaagtc gtcgctgccg gccggtacgg agtacacgcg ggtcgtgccc ccgttgggcg
    23401 gatcctgggt gagcgcgccc acgagttcgg agcccacgcg gcccgccgcc cggtcgtcga
    23461 gcacggcggt gcggtcgacc ggccgtacgg aggtcaggta cgcggtcagc gggatggcca
    23521 ggaactgctc cggggcgcgg gtgacgcgca cggtccgcag cctctcgtcg tccagtcgcg
    23581 gatcgtccac ggagatcagg accatggcgg tgtgcgcgga ctggtagcgc ggggccgcgg
    23641 ccagtgccgc gggaaccgtg tccggcccga ggaccgcgct cacggcggcc ccggtgaagc
    23701 gctcggcggc ctgccgggcc cgggcggggt cgccccggtc gtcgtaggtg tcgagggcga
    23761 gccggaaccc gccgcccgcg cgtgcgttgt ggtgcgccac ggcgagtcgc gcgccgcgct
    23821 cctgggccac gccgtccgtc cctccggcac cggtcagatc ggcctggaag ccgagcgtgt
    23881 acacgggcgg cccgccgccg gagccccggc ccaccgtcag atacgcggcg gtgccgccgc
    23941 ccagggccag caccgaggcc gccgcgctcc ccagtgccag cacccgccgc cgggccggcg
    24001 cgcggtcccc ggccggggcc gccggc
//
