BGC0002501 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002501 (Penicillium steckii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	53,110	penigainamide A/penigainamide B/penigainamide C/adametizine A/FA2097/outovirin A/outovirin C/pretrichodermamide C	other:other	100%

BGC0002501 - Region 1 - NRPS

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Location: 1 - 53,110 nt. (total: 53,110 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 53,111
Label		BGC0002501

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002501	0.80	Alkaloid	penigainamide A, penigainamide B, penigainamide C, adametizine A, FA2097, outovirin A, outovirin C, pretrichodermamide C	Penicillium steckii
BGC0001893	0.33	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002610	0.33	Terpene	stellatic acid	Aspergillus stellatus
BGC0002736	0.33	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002181	0.33	Terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0002721	0.32	Saccharide	α-hydroxynitrile glucoside, β-hydroxynitrile glucoside, γ-hydroxynitrile glucoside	Hordeum vulgare subsp. vulgare
BGC0001528	0.32	Terpene	betaestacin	Phoma betae
BGC0002162	0.31	Terpene	sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8	Aspergillus fischeri NRRL 181
BGC0000687	0.31	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0002391	0.31	Terpene	zealexin B2, zealexin C2	Zea mays

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002501	0.99	Alkaloid	penigainamide A, penigainamide B, penigainamide C, adametizine A, FA2097, outovirin A, outovirin C, pretrichodermamide C	Penicillium steckii
BGC0002670	0.67	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0001893	0.67	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002610	0.67	Terpene	stellatic acid	Aspergillus stellatus
BGC0002736	0.66	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0002181	0.66	Terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0002721	0.65	Saccharide	α-hydroxynitrile glucoside, β-hydroxynitrile glucoside, γ-hydroxynitrile glucoside	Hordeum vulgare subsp. vulgare
BGC0001528	0.65	Terpene	betaestacin	Phoma betae
BGC0001989	0.65	Other	pulcherrimin	Kluyveromyces lactis
BGC0002162	0.65	Terpene	sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8	Aspergillus fischeri NRRL 181

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 38666:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

PenP

Search NORINE for peptide: strict or relaxed

AMP-binding (584..968): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGHIYVMGGK
Nearest Stachelhaus code(s):: Phe DGHIYVMCGK (85% 8Å match)
Stachelhaus code match:: 90% (moderate)