BGC0002504: nocardiopsistin A biosynthetic gene cluster from Nocardiopsis sp.
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 26,000 nt. (total: 26,000 nt).
This entry is originally from NCBI GenBank MT633092.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002504
Short description nocardiopsistin A biosynthetic gene cluster from Nocardiopsis sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MT633092.1
1 - 26000
via Knock-out studies
Compounds
  • nocardiopsistin A
  • nocardiopsistin B
  • nocardiopsistin C
Species Nocardiopsis sp. [taxonomy]
References
Chemical products information
nocardiopsistin A Evidence:
Copy SMILES
Chemical database entries
NPAtlas
nocardiopsistin B Evidence:
Copy SMILES
Chemical database entries
NPAtlas
nocardiopsistin C Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QOP59266.1
1 - 591 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • QOP59267.1
    799 - 972 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • QOP59268.1
      1128 - 2609 (+) FAD-binding monooxygenase
        copy AA seq
        copy Nt seq
        • QOP59269.1
        2662 - 2988 (+) polyketide synthesis cyclase
          copy AA seq
          copy Nt seq
          • QOP59270.1
          3050 - 4318 (+) beta-ketoacyl-ACP synthase
            copy AA seq
            copy Nt seq
            • QOP59271.1
            4315 - 5529 (+) ketosynthase chain-length factor
              copy AA seq
              copy Nt seq
              • QOP59272.1
              5588 - 5839 (+) acyl carrier protein
                copy AA seq
                copy Nt seq
                • QOP59273.1
                6005 - 6790 (+) keto-reductase
                  copy AA seq
                  copy Nt seq
                  • QOP59274.1
                  6831 - 7778 (+) cyclase/dehydrase
                    copy AA seq
                    copy Nt seq
                    • QOP59275.1
                    7783 - 9261 (+) oxidoreductase
                      copy AA seq
                      copy Nt seq
                      • QOP59276.1
                      9271 - 10866 (+) methylmalonyl-CoA carboxyltransferase alpha
                        copy AA seq
                        copy Nt seq
                        • QOP59277.1
                        11079 - 12125 (+) 3-oxoacyl-ACP synthase
                          copy AA seq
                          copy Nt seq
                          • QOP59278.1
                          12122 - 13135 (+) malonyl CoA-acyl carrier protein transacylase
                            copy AA seq
                            copy Nt seq
                            • QOP59279.1
                            13161 - 13631 (-) MarR family transcriptional regulator
                              copy AA seq
                              copy Nt seq
                              • QOP59280.1
                              14338 - 15165 (+) SARP family transcriptional regulator
                                copy AA seq
                                copy Nt seq
                                • QOP59281.1
                                15098 - 16360 (-) FAD-binding oxygenase
                                  copy AA seq
                                  copy Nt seq
                                  • QOP59282.1
                                  16496 - 17140 (-) NmrA-family oxidoreductase
                                    copy AA seq
                                    copy Nt seq
                                    • QOP59283.1
                                    18022 - 19311 (+) halogenase
                                      copy AA seq
                                      copy Nt seq
                                      • QOP59284.1
                                      19328 - 20674 (+) transporter
                                        copy AA seq
                                        copy Nt seq
                                        • QOP59285.1
                                        22624 - 23367 (+) GntR family transcriptional regulator
                                          copy AA seq
                                          copy Nt seq
                                          • QOP59286.1
                                          23592 - 24653 (-) hypothetical protein
                                            copy AA seq
                                            copy Nt seq
                                            • QOP59287.1
                                            24650 - 25990 (-) hypothetical protein
                                              copy AA seq
                                              copy Nt seq
                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              Entry added
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              Detailed domain annotation
                                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                              A domain glossary is available here, and an explanation of the visualisation is available here.
                                              Selected features only
                                              Show module domains
                                              Similar known gene clusters from MIBiG 4.0
                                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                              Click on reference genes to show details of similarities to genes within the current region.
                                              Click on an accession to open that entry in the MiBIG database.