LOCUS       BGC0002505             25320 bp    DNA     linear   PLN 14-OCT-2020
DEFINITION  Xenoacremonium sp. BF-2018a xenoacremone A gene cluster, complete
            sequence.
ACCESSION   BGC0002505
VERSION     BGC0002505
KEYWORDS    .
SOURCE      Xenoacremonium sp. BF-2018a
  ORGANISM  Xenoacremonium sp. BF-2018a
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Xenoacremonium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:52:20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 25320
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..25320
                     /db_xref="taxon:2480843"
                     /mol_type="genomic DNA"
                     /organism="Xenoacremonium sp. BF-2018a"
                     /strain="ML-31"
     protocluster    1..25320
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[8720:21049]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8721..21049
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..25320
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[8720:21049]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      8721..21049
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..25320
                     /SMILES="C([*])C(-O)(C)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..25320
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002505"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25320
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(<785..>2062)
                     /product="XenA"
     CDS             complement(785..2062)
                     /codon_start=1
                     /note="zinc-regulated transporter"
                     /product="XenA"
                     /protein_id="QOJ72659.1"
                     /transl_table=11
                     /translation="MFTFSPSFMFDFELTRILGSASSGGCDVGEFKSALNTIKKNDPES
                     WYAAWKQQAERAQKIADEAAKAGYRVLARNAYLRASNYFRATSYMFNNDDARVIPFTDK
                     SIACFKRATELMDGEVLSVDIPYEDGITLPGYLFLPPQYARVPGKIPVVMYAAGADSTK
                     EELYFLYGGTGPQLGYAILCLEGPGQGLLLKKNKIPLRPDFEVVAAKVLDFLDDLSRSQ
                     PALELDLGRIAMAGAATGGYFALRAATDPRIKACVSIDPFFSLWELSLTRVPQAFFKLW
                     DSGWVPDGTFDAFTDRHARGNFQAGWEINLGKSSMGVEKATGMFRRFKQFTLEPEDGTK
                     ILDKVTCPVFITGPGSGQEMYASADDSTFKIQRLLTKVPDSKKEIWVPNDVADGGLTAK
                     IGAWALLAQKTFEFLDKHFEVKRKEL"
     misc_feature    785..24646
                     /note="xenoacremone A gene cluster"
     mRNA            <4862..>6055
                     /product="XenB"
     CDS             4862..6055
                     /codon_start=1
                     /note="cluster regulator"
                     /product="XenB"
                     /protein_id="QOJ72660.1"
                     /transl_table=11
                     /translation="MGSNLAGTQCLDSLDFVLQGGAIDDEQLRITPPEDCFDVNFDFIS
                     PPVPRTMPDFGIYEFGSEATSGSLEPGPFMPIEHAATSNPAAEKPNPGALVHVSSMQQE
                     SVEQMSALNVEIHRQLSVVSQVAKEYATTEPSLMDSTDQRNRLSSAVVSMIQGLQTFQT
                     LLLEILGAARQGSPKEPASRASMHSSQKNDTSLQTSWTWLNTKNDLSSIADADTGDTIS
                     DFETGDRQTISRSDTNSEVRPIPESPSQTTWLDMSTSLLIISCYINLIQLCRDVFAAIR
                     GALSVPGHQTTLLELSGFQISGVSIHEDSDLQIIVLTQVVVRLIDRIGLYLGYSGTSTA
                     EAGKRDESDFNCKTISPQLLDFVLGQKEMEGQPSCKERIEALREEIRKLSEVVYKPI"
     mRNA            complement(<6587..>6958)
                     /product="XenC"
     CDS             complement(6587..6958)
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="XenC"
                     /protein_id="QOJ72661.1"
                     /transl_table=11
                     /translation="MSSLLLSDVLSYGIFGFSALCVQAHLTSKFTPSFSRNLEEKLPLH
                     NKAVFWWLGISDSALRYVFVSINIAVCVLLWSPELRSFGLKFTLGLLGVGFYSDMKLGE
                     SPIPHLLLVSTVGAAILVR"
     mRNA            <7716..>8204
                     /product="XenD"
     CDS             7716..8204
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="XenD"
                     /protein_id="QOJ72662.1"
                     /transl_table=11
                     /translation="MSLIPSSIRLLRLLPALSSTSVLMFALDEHLIFGTWMHPTLRERA
                     NTTLPPWWTKGGLRWRWVIIIGYPLTYLLGILNLLVARDELQATGSTLWYTTGLLFSIA
                     HMAYVGTALNWIANIENGMPKGNVTYSMGNWLKMNWTRALITDLPAWVCFITAALKVL"
     mRNA            complement(join(<8721..11647,11718..13526,13580..14280,
                     14334..16590,16637..16863,16916..19989,20045..>21049))
                     /product="XenE"
     CDS             complement(join(8721..11647,11718..13526,13580..14280,
                     14334..16590,16637..16863,16916..19989,20045..21049))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (15-450). E-value:
                     1.8e-165. Score: 542.8. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (561-876). E-value: 3.5e-92.
                     Score: 300.8. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (949-1122). E-value: 1.4e-22.
                     Score: 72.6. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1387-1597). E-value: 9.2e-70.
                     Score: 226.7. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2132-2305). E-value: 2.1e-47.
                     Score: 153.3. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2446-2491). E-value: 1.4e-09.
                     Score: 30.1. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2581-2873). E-value:
                     5.6e-65. Score: 211.1. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3044-3453). E-value:
                     1.1e-89. Score: 292.7. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3569-3638). E-value:
                     1.6e-13. Score: 42.9. Matches aSDomain:
                     nrpspksdomains_QOJ72663.1_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3678-3903). E-value: 1.7e-58. Score:
                     189.5. Matches aSDomain: nrpspksdomains_QOJ72663.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 220.3; E-value:
                     7.3e-67)"
                     /gene_kind="biosynthetic"
                     /note="hybrid PKS-NRPS"
                     /product="XenE"
                     /protein_id="QOJ72663.1"
                     /sec_met_domain="itr_KS (E-value: 1.2e-173, bitscore:
                     566.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.4e-93, bitscore: 300.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.2e-42, bitscore:
                     134.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1e-55, bitscore:
                     177.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-92, bitscore:
                     297.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2e-14, bitscore:
                     42.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.7e-43, bitscore:
                     136.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGQDPVKESGQREPIAVVGSGFRFPGSSNNPSKLWDLLVKPRDL
                     LTKIPENRFNSDAFYHPKPFHHGTSDVRESYFLEEDHRQFDAAFFNIKPVEVHAIDPQQ
                     RILMEAVYESLEAAGLSMESLAGSRTGVYVGLMCADYVDLLNNDVNSLPTYTPTGTARS
                     IMSNRISYFFDWHGPSMTIDTACSSSLVAVHQAVQLLRSGDSDVAVAAGANLMLGPLPY
                     IAESKLQMLSSNSRSRMWDIDASGYARGEGVAAVVLKRLSSAIADGDQIECIIRESGIN
                     QDGRTKGITMPSSVAQADLISRTYAKAGLNPRDPTERCQYFEAHGTGTAAGDPKEAEAI
                     SKAFFHPGEDISGKTDPLYVGSIKTVIGHTEGTAGLAGLLKASLAVQHGIVPPNLLFNQ
                     LSPAVEPFYTNLEVLTSPRPWPKLAEGTPRRASINSFGFGGTNAHCIIENYIPSPAHTD
                     RAITTRQFTPFNFSAASEKSLRGILTDYSNYLRLNPEVSLQDLSYTLYARRSEHAVRVH
                     ISAGSTTDLYTRIDDLLQVPSSGGNAQSIGTRSKILSRPVRALGVFTGQGAQWPSMGRE
                     LVLNSPYAKEVVQKLDLVLQSLPEPERPDWSLMYELTCDASQSRLNTAVIAQPLCTVVQ
                     IILFDLLSSAGVKLQAVVGHSSGEIAAAYAAGYLTREDALKIAYYRGYFTNLTPSDRPG
                     AMMAIGTSAEDAEELCSLPMFQGRLAVAAVNSSSSVTISGDRDAIEQAKEVLEDEKKFA
                     RLLKVDKAYHSSHMVPCAEGYLEALKNSEIHPLSGTDDCVWHSSTHKNKYSHGDGALAG
                     QYWADNMIQPVLFSHAVEAAASAGDAFDIAIEVGPHPALKGPALQTLQEVQKDTIPYTG
                     LLNRGKDDIEALSDALGYLWTQFTPSLIDFRGFDLLASGGEQRSLIRNLPTYHWDHDKI
                     FWHKSRAVKAFLGQKNIPNPLLGSRTTDVMEQEIRWRNLLRLSELPWVRGHQLQGQVIY
                     PATAYISTAVEAARFLVPKGDNIALIEVEDFSLGKPLVFAEDAAGIETVFTLSDIAKEN
                     DTTYSASFIYHASTNAETEQLSTHAIGRVIVITGETSSHWLPSRQKDLPNLVDIPEDRF
                     YASLEPLGYAYSGYFKTMSSIKRRLNFSSTKIRVPPQDDEPEKMLLHPALLDTALQGIF
                     LAYCWPGDGSLEQLHVPTGIKNFRVNVGLCQQVLTPETDVSSCTQLTGNPLATKHLNGD
                     VEIYADDGAGLVQMEGLRVVAFAEQTEDADRAIFSEHVWDVLAPNCERAMGGKRATLQD
                     YEFAYGMERVVVYYMKQLVTLFPESLRKIMNLEWHFECMFAFFTDVLTTLEAGERRTAR
                     REWLQDTAADVEGIKARYAHTVDMQLTCAVGDNLPAVLRGESTILQHLTKDNLLNRFYE
                     VGLGLKEVSGYLGKIVEQVVHRHPRMKILEIGKSGTGGATKVIMRGIGRSFSSYTYTDI
                     SPNFFESAQEVFSAVADKMIFKTLDVEKDITEQSFEEHSYDLVVASLVLHATTNLKRTL
                     TNARRLLKPGGYLIFQEICDNDIARVGFLICAVPGWWLGQDDGRKLSPCVSTSEWHNLL
                     LETGFSGADSPMPEYDAAPYPLAVIVSQAVDDRIALLREPLSLVQNDASVGEPWDLVLV
                     GGQTSKTAMIIEQISGLITSSGVTHSVFKTIDEVDGTRISPTTAILCLADLDEPVFKGL
                     SSTTLEGLQRLFETQRTVLWITQGCRSEDPWMNMSVGLGRTLVLENPDLALQFLDLEPG
                     VEPNPRQLLEVLLRLRQSDIWEKEGKFDDVLWTNEHELAYDKGDLTLSRVHLSGALNDR
                     YNAAKRTVLEAKNPQETPLNLSLGPSLKQFLVLDDVLVAKTLSSWELKDDSETLIKVTH
                     SLLMPALAAPTPLYLILGTINKTKKSVLSIADNNGSYALVASNKVLAIDVPAGQESQLL
                     SLFNTRLQVDSMLSLCESDSTLLIHEPSPDLASAIAACGSSGKINVVFTTSTSSGDSTW
                     TRIDAYSTQRAIRSLLPENVSVFIDCSAGSQSRRTASLIASCLLPSCFQTTISGVQSLQ
                     RIRGLSPTDLCQKLNDALAWASKELAAPSNPGTLPSIKLETLIDDSAVASTTQAVVDWS
                     TATSVPVQVSTVDNHVTFKGNNTYVLFGLTSDLAQSICDWMVSRGARNIVLTSRNPKID
                     SNWIELLKGAGVRLEAFANDITNKDALSSLVHHIRKNFPPIAGVAHGAMVLDDVSFFEM
                     PYEKMTKVLGPKVQGAILLDEIFQDTSLDFFVFFSSVTAIAGNRGQSAYTSANMFMTSL
                     ASQRRDKGLAASILHLGAVMGVGYINRGFSDAFFTTLRRAGFMMMSERGLHLLFGEAVL
                     ASNPHSGRNPEVITALELSRLGDKPPLWTKFPRFQHCLQADDGANKRAKKKTAAVSTKL
                     KLAEATTAEEILEIVQDAFYLKLQVALQIPDETDKSQVLASGTDDLGIDSLVAVEIRSW
                     FLKELETEIPVFKVLSGGSVTQLVEYAIGSMPAELTPNRADSAKASEPEPEAPATLMPP
                     PDSVSSSPSSLPKTSASGSSQQMSEGSSKTSEQGDAQDKKEESPSESVNDISELTYEKV
                     LPVSPGQSRFWFLKHLLEDQTTANNTIWVSIQGTIRLNDLEMAIRKVAARHEALRTSFF
                     MDENQKPIQAISETSRLYLEKKTLSSGSQAEREFEGLKKHVYDIEHGECMRLVYLEVTD
                     TESYLLIGSHHIIMDGISLEVFLKDIEKAYNGQSLSNQVYQYSDYSEKLRQELEQGTMQ
                     EEINYWKSEFADVPSPLPLLPFAAEKQRKSLAAYSHTSVSRLVDPRVARQISNTCHKLK
                     ANVFHFYLGVFEVLLFKLFGNNDVCIGMADANRWNEKVSQSIGMYLNLLPLRFHLDGRQ
                     SFEAMLKDTRRKAYLAMSNSRLPFDVLLDNVICERSSAFSPLFQAFINYRQGVNEKRVL
                     GNATGATKELSLPRAGYDISLDIIENPGNDTRVTVMLQKALYSDNESSRVLDLYFKLLN
                     DLSSSSKKMLEEVSLFTEQEISNSIQLGQGPVLPSQWPETLVHRIDAMIAVHTDKVALK
                     EITGKSWTYLQLEEEINRVSSVLIQANVTSGSTVAIYQEASPNFVFSLLAVLRIGAIYV
                     PLDCNLPEGRLRLVLAECKPSALLADGKTLSQIGSLGLSPSVTILDVSRLPAASASISP
                     VFTKAANPAAILFTSGSTGVPKGVVLSHGSLRNHVEALVHTHGFGSETVLQQSSVGFDM
                     SMNQVFMALANGGSLVIVPESLRKDSSAIAKILLEQNITYTSATPSEYFAWLRHGSDDL
                     LRNKSWKYATAGGEKFTPKLLQAFQKLKSAFSHSFHAFNAYGPTECSMSSNELEVNLDG
                     HSAQFITAGRALPNYAVYIVDENATPQTIEIPGEICIAGAGVALEYLNNPVETAKKFLK
                     DPFASVSAIERGWNRMYRTGDKGVLRPDGTLEILGRIEGDTQIKLRGLRIEMQDIEQSI
                     LKAGEGRVKEAIVTPRGDPTILVAHAVVSPIVSIDNEREYLRGLAASLPLPQYMRPAAI
                     IPIATMPLNASGKIDRRALQNLDIPSTLQQKTRSKRKLTDTESKLAQIWVEVLPQQLQE
                     VYAIDETSDFFQVGGNSMLLIELRELVKKRFQVHLPLLRFFEHSTLGAMAAAIQDTSPG
                     EKLEINWDVETEVPSAYSELNTQEPAQSHSSHKTIVLTGATGFLGKYLLNLLTEAPDVD
                     KIHCIAIRNREKLANFTNSAKVVIHDGDLASPRCGLSEADATSVFGSANVIIHNGADVS
                     FLKTYSSLRASNVLSTKELVKLALPHHIPIHYISTATVGKLNKSDSLAPESLAQYPPGP
                     SFVDGYAASKWASEVFLEKTTRQFGLPTFIHRPSSITGDGAGENDIVPSVLKYSAMIKA
                     LPDSSKWTGYIDLITVEKAAAGIADSVLQGRLVNVTATEAEYLHHAGEKVIPAQSIKTI
                     LTADDGPQWESVSMKNWVEKAIQNGMNPLVGEFLLSIDKGQGMQIGQKLLSKTDGSKNE
                     F"
     aSDomain        complement(9012..9686)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_TD.1"
                     /evalue="1.70E-58"
                     /label="QOJ72663.1_TD.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3903"
                     /protein_start="3678"
                     /score="189.5"
                     /tool="antismash"
                     /translation="IVLTGATGFLGKYLLNLLTEAPDVDKIHCIAIRNREKLANFTNSA
                     KVVIHDGDLASPRCGLSEADATSVFGSANVIIHNGADVSFLKTYSSLRASNVLSTKELV
                     KLALPHHIPIHYISTATVGKLNKSDSLAPESLAQYPPGPSFVDGYAASKWASEVFLEKT
                     TRQFGLPTFIHRPSSITGDGAGENDIVPSVLKYSAMIKALPDSSKWTGYIDLITVEKAA
                     AGI"
     aSModule        complement(9012..13047)
                     /complete
                     /domains="nrpspksdomains_QOJ72663.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_QOJ72663.1_AMP-binding.1"
                     /domains="nrpspksdomains_QOJ72663.1_PP-binding.1"
                     /domains="nrpspksdomains_QOJ72663.1_TD.1"
                     /final_module
                     /locus_tags="QOJ72663.1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(9807..10013)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PP-binding.1"
                     /evalue="1.60E-13"
                     /label="QOJ72663.1_PP-binding.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3638"
                     /protein_start="3569"
                     /score="42.9"
                     /tool="antismash"
                     /translation="KLAQIWVEVLPQQLQEVYAIDETSDFFQVGGNSMLLIELRELVKK
                     RFQVHLPLLRFFEHSTLGAMAAAI"
     CDS_motif       complement(10329..10379)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0015"
                     /evalue="6.40E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3464"
                     /protein_start="3447"
                     /score="15.7"
                     /tool="antismash"
                     /translation="DTQIKLRGLRIEMQDIE"
     aSDomain        complement(10362..11588)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_AMP-binding.1"
                     /evalue="1.10E-89"
                     /label="QOJ72663.1_AMP-binding.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3453"
                     /protein_start="3044"
                     /score="292.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AVHTDKVALKEITGKSWTYLQLEEEINRVSSVLIQANVTSGSTVA
                     IYQEASPNFVFSLLAVLRIGAIYVPLDCNLPEGRLRLVLAECKPSALLADGKTLSQIGS
                     LGLSPSVTILDVSRLPAASASISPVFTKAANPAAILFTSGSTGVPKGVVLSHGSLRNHV
                     EALVHTHGFGSETVLQQSSVGFDMSMNQVFMALANGGSLVIVPESLRKDSSAIAKILLE
                     QNITYTSATPSEYFAWLRHGSDDLLRNKSWKYATAGGEKFTPKLLQAFQKLKSAFSHSF
                     HAFNAYGPTECSMSSNELEVNLDGHSAQFITAGRALPNYAVYIVDENATPQTIEIPGEI
                     CIAGAGVALEYLNNPVETAKKFLKDPFASVSAIERGWNRMYRTGDKGVLRPDGTLEILG
                     RIEGDTQIKL"
     CDS_motif       complement(10503..10583)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0014"
                     /evalue="1.80E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3406"
                     /protein_start="3379"
                     /score="33.1"
                     /tool="antismash"
                     /translation="IPGEICIAGAGVALEYLNNPVETAKKF"
     CDS_motif       complement(11121..11180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0013"
                     /evalue="5.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3200"
                     /protein_start="3180"
                     /score="25.0"
                     /tool="antismash"
                     /translation="AAILFTSGSTGVPKGVVLSH"
     CDS_motif       complement(11373..11414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0012"
                     /evalue="1.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="QOJ72663.1"
                     /protein_end="3116"
                     /protein_start="3102"
                     /score="12.4"
                     /tool="antismash"
                     /translation="LAVLRIGAIYVPLD"
     CDS_motif       complement(12016..12114)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0011"
                     /evalue="2.20E-04"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2925"
                     /protein_start="2892"
                     /score="13.5"
                     /tool="antismash"
                     /translation="AMSNSRLPFDVLLDNVICERSSAFSPLFQAFIN"
     aSDomain        complement(12172..13047)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-65"
                     /label="QOJ72663.1_Condensation_LCL.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2873"
                     /protein_start="2581"
                     /score="211.1"
                     /tool="antismash"
                     /translation="VLPVSPGQSRFWFLKHLLEDQTTANNTIWVSIQGTIRLNDLEMAI
                     RKVAARHEALRTSFFMDENQKPIQAISETSRLYLEKKTLSSGSQAEREFEGLKKHVYDI
                     EHGECMRLVYLEVTDTESYLLIGSHHIIMDGISLEVFLKDIEKAYNGQSLSNQVYQYSD
                     YSEKLRQELEQGTMQEEINYWKSEFADVPSPLPLLPFAAEKQRKSLAAYSHTSVSRLVD
                     PRVARQISNTCHKLKANVFHFYLGVFEVLLFKLFGNNDVCIGMADANRWNEKVSQSIGM
                     YLNLLPLRFHL"
     CDS_motif       complement(12181..12270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0010"
                     /evalue="5.50E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2870"
                     /protein_start="2840"
                     /score="15.7"
                     /tool="antismash"
                     /translation="DVCIGMADANRWNEKVSQSIGMYLNLLPLR"
     CDS_motif       complement(12601..12663)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0009"
                     /evalue="3.90E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2730"
                     /protein_start="2709"
                     /score="22.7"
                     /tool="antismash"
                     /translation="HHIIMDGISLEVFLKDIEKAY"
     CDS_motif       complement(12868..12954)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0008"
                     /evalue="1.30E-07"
                     /label="C2_dual_024-063"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2641"
                     /protein_start="2612"
                     /score="24.2"
                     /tool="antismash"
                     /translation="IQGTIRLNDLEMAIRKVAARHEALRTSFF"
     aSDomain        complement(13318..13452)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PKS_PP.1"
                     /evalue="1.40E-09"
                     /label="QOJ72663.1_PKS_PP.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2491"
                     /protein_start="2446"
                     /score="30.1"
                     /tool="antismash"
                     /translation="GTDDLGIDSLVAVEIRSWFLKELETEIPVFKVLSGGSVTQLVEYA
                     "
     aSModule        complement(13318..21004)
                     /complete
                     /domains="nrpspksdomains_QOJ72663.1_PKS_KS.1"
                     /domains="nrpspksdomains_QOJ72663.1_PKS_AT.1"
                     /domains="nrpspksdomains_QOJ72663.1_PKS_DH.1"
                     /domains="nrpspksdomains_QOJ72663.1_cMT.1"
                     /domains="nrpspksdomains_QOJ72663.1_PKS_KR.1"
                     /domains="nrpspksdomains_QOJ72663.1_PKS_PP.1"
                     /iterative
                     /locus_tags="QOJ72663.1"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(join(13929..14280,14334..14500))
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PKS_KR.1"
                     /evalue="2.10E-47"
                     /label="QOJ72663.1_PKS_KR.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2305"
                     /protein_start="2132"
                     /score="153.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="TYVLFGLTSDLAQSICDWMVSRGARNIVLTSRNPKIDSNWIELLK
                     GAGVRLEAFANDITNKDALSSLVHHIRKNFPPIAGVAHGAMVLDDVSFFEMPYEKMTKV
                     LGPKVQGAILLDEIFQDTSLDFFVFFSSVTAIAGNRGQSAYTSANMFMTSLASQRRDKG
                     LAASILHLGA"
     CDS_motif       complement(13968..14078)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0007"
                     /evalue="1.20E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2292"
                     /protein_start="2255"
                     /score="59.6"
                     /tool="antismash"
                     /translation="LDFFVFFSSVTAIAGNRGQSAYTSANMFMTSLASQRR"
     CDS_motif       complement(14402..14500)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0006"
                     /evalue="7.70E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="2165"
                     /protein_start="2132"
                     /score="41.0"
                     /tool="antismash"
                     /translation="TYVLFGLTSDLAQSICDWMVSRGARNIVLTSRN"
     aSDomain        complement(join(16106..16590,16637..16781))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="9.20E-70"
                     /label="QOJ72663.1_cMT.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="1597"
                     /protein_start="1387"
                     /score="226.7"
                     /tool="antismash"
                     /translation="LQHLTKDNLLNRFYEVGLGLKEVSGYLGKIVEQVVHRHPRMKILE
                     IGKSGTGGATKVIMRGIGRSFSSYTYTDISPNFFESAQEVFSAVADKMIFKTLDVEKDI
                     TEQSFEEHSYDLVVASLVLHATTNLKRTLTNARRLLKPGGYLIFQEICDNDIARVGFLI
                     CAVPGWWLGQDDGRKLSPCVSTSEWHNLLLETGFSGADSPMPEYDAA"
     aSDomain        complement(17629..18147)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PKS_DH.1"
                     /evalue="1.40E-22"
                     /label="QOJ72663.1_PKS_DH.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="1122"
                     /protein_start="949"
                     /score="72.6"
                     /tool="antismash"
                     /translation="PLLGSRTTDVMEQEIRWRNLLRLSELPWVRGHQLQGQVIYPATAY
                     ISTAVEAARFLVPKGDNIALIEVEDFSLGKPLVFAEDAAGIETVFTLSDIAKENDTTYS
                     ASFIYHASTNAETEQLSTHAIGRVIVITGETSSHWLPSRQKDLPNLVDIPEDRFYASLE
                     PLGYAYSGYF"
     CDS_motif       complement(17989..18066)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0005"
                     /evalue="8.30E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="QOJ72663.1"
                     /protein_end="1002"
                     /protein_start="976"
                     /score="31.1"
                     /tool="antismash"
                     /translation="WVRGHQLQGQVIYPATAYISTAVEAA"
     aSDomain        complement(18367..19311)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PKS_AT.1"
                     /evalue="3.50E-92"
                     /label="QOJ72663.1_PKS_AT.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="876"
                     /protein_start="561"
                     /score="300.8"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPSMGRELVLNSPYAKEVVQKLDLVLQSLPEPERPDW
                     SLMYELTCDASQSRLNTAVIAQPLCTVVQIILFDLLSSAGVKLQAVVGHSSGEIAAAYA
                     AGYLTREDALKIAYYRGYFTNLTPSDRPGAMMAIGTSAEDAEELCSLPMFQGRLAVAAV
                     NSSSSVTISGDRDAIEQAKEVLEDEKKFARLLKVDKAYHSSHMVPCAEGYLEALKNSEI
                     HPLSGTDDCVWHSSTHKNKYSHGDGALAGQYWADNMIQPVLFSHAVEAAASAGDAFDIA
                     IEVGPHPALKGPALQTLQEVQKDTIPYTGLLNRG"
     CDS_motif       complement(18949..19059)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0004"
                     /evalue="4.30E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="QOJ72663.1"
                     /protein_end="682"
                     /protein_start="645"
                     /score="38.0"
                     /tool="antismash"
                     /translation="GVKLQAVVGHSSGEIAAAYAAGYLTREDALKIAYYRG"
     CDS_motif       complement(19264..19311)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0003"
                     /evalue="3.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="577"
                     /protein_start="561"
                     /score="16.2"
                     /tool="antismash"
                     /translation="VFTGQGAQWPSMGREL"
     aSDomain        complement(join(19645..19989,20045..21004))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72663.1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-165"
                     /label="QOJ72663.1_PKS_KS.1"
                     /locus_tag="QOJ72663.1"
                     /protein_end="450"
                     /protein_start="15"
                     /score="542.8"
                     /tool="antismash"
                     /translation="IAVVGSGFRFPGSSNNPSKLWDLLVKPRDLLTKIPENRFNSDAFY
                     HPKPFHHGTSDVRESYFLEEDHRQFDAAFFNIKPVEVHAIDPQQRILMEAVYESLEAAG
                     LSMESLAGSRTGVYVGLMCADYVDLLNNDVNSLPTYTPTGTARSIMSNRISYFFDWHGP
                     SMTIDTACSSSLVAVHQAVQLLRSGDSDVAVAAGANLMLGPLPYIAESKLQMLSSNSRS
                     RMWDIDASGYARGEGVAAVVLKRLSSAIADGDQIECIIRESGINQDGRTKGITMPSSVA
                     QADLISRTYAKAGLNPRDPTERCQYFEAHGTGTAAGDPKEAEAISKAFFHPGEDISGKT
                     DPLYVGSIKTVIGHTEGTAGLAGLLKASLAVQHGIVPPNLLFNQLSPAVEPFYTNLEVL
                     TSPRPWPKLAEGTPRRASINSFGFGGTNAHCIIENY"
     CDS_motif       complement(join(19987..19989,20045..20089))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0002"
                     /evalue="3.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="QOJ72663.1"
                     /protein_end="336"
                     /protein_start="320"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YFEAHGTGTAAGDPKE"
     CDS_motif       complement(20474..20521)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QOJ72663.1_0001"
                     /evalue="5.20E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="QOJ72663.1"
                     /protein_end="192"
                     /protein_start="176"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVA"
     mRNA            complement(<21789..>23096)
                     /product="XenF"
     CDS             complement(21789..23096)
                     /codon_start=1
                     /note="Prins-like rase"
                     /product="XenF"
                     /protein_id="QOJ72664.1"
                     /transl_table=11
                     /translation="MSPAANMFRTLTLTALVSAVVSAYESQVPLNPQFPEYLNEEWDDS
                     CSISKSTAYDVHDGPNTFSSSPSEDIHSVKISPHVNATNWEQWEFDGLSHTGLSGLLMA
                     FSRDATYAFFGQGNLRVEFYITLGDGSIIQELDFISESYVIDCPDFTAGIWNSTDRSYS
                     FYVTKDHQFARLKFDSWRVRGGFTMSSSTRPHLADGSPWTPDGGKPDATEVSPGLFYGL
                     SMGGAEVDVDATLSSGKRITFKGRGGSTRLWATEGWLKLCDGWKVIRAWAGPYSIVYWD
                     VLSRIDRGVRYVSGHLFYHDELLVGSRVGQPSDKADYVLFNDQFDGEMSGKYKDKNTGH
                     HLEFASPARDKKWTFDVQHIVTQYEIGAGAGFGMSGFANRVVGGEVGGVQYEGKGQSEQ
                     TYWPEHIEEWKIWLVWGLGFLGRGKTYVMKLVGYVL"
     mRNA            join(<23478..24046,24103..>24646)
                     /product="XenG"
     CDS             join(23478..24046,24103..24646)
                     /NRPS_PKS="Domain: PKS_ER (31-233). E-value: 6.1e-22.
                     Score: 70.0. Matches aSDomain:
                     nrpspksdomains_QOJ72665.1_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 169.4; E-value: 1.8e-51)"
                     /gene_kind="biosynthetic-additional"
                     /note="trans-enoyl reductase"
                     /product="XenG"
                     /protein_id="QOJ72665.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.1e-13, bitscore:
                     38.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTGLPQLPPSQKAVIQSEKTPGAFEVSENRPVPVPKANELIVK
                     VSAVSLNHCDWKMPGRVPCPGAVDGADYSGTIVRMGEIAALKSGFQIGDRVAGAQMASS
                     RRRPWAGAFTEYLRDEYDMVWKVPDNLSWEQAAAIGCATTSTVGMALWISMKLPGTPEN
                     PIKEPKLVLVYGGSTASGTFAIQLLKLSGYKVVTTCSPKNFKLVEEYGADKAFDYHSAT
                     CGEDIRAYTNNTLEYALDIITEARTIRHCYAAIGRGGGRYCGFELLPEDLIATMRKSVK
                     AEWVMGLEMTGLEIDLPGGYYRKANPELHTWFCDWKERYVALFGSGKTKTHPITVRQGG
                     LEKVIDGIESMRRREVSGEKIVYPLYIKGC"
     aSDomain        join(23571..24046,24103..24232)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QOJ72665.1_PKS_ER.1"
                     /evalue="6.10E-22"
                     /label="QOJ72665.1_PKS_ER.1"
                     /locus_tag="QOJ72665.1"
                     /protein_end="233"
                     /protein_start="31"
                     /score="70.0"
                     /tool="antismash"
                     /translation="RPVPVPKANELIVKVSAVSLNHCDWKMPGRVPCPGAVDGADYSGT
                     IVRMGEIAALKSGFQIGDRVAGAQMASSRRRPWAGAFTEYLRDEYDMVWKVPDNLSWEQ
                     AAAIGCATTSTVGMALWISMKLPGTPENPIKEPKLVLVYGGSTASGTFAIQLLKLSGYK
                     VVTTCSPKNFKLVEEYGADKAFDYHSATCGEDIRAYTNN"
ORIGIN
        1 cttcccgctc cggaccgtgg cacttggcac aactcaacca cgtggcaggg ggccttccaa
       61 gacttcggga ttctacacgg tcgcacgccc aggtaggctg acgcgtgcta tccacgtgcc
      121 tcagcatcaa cagtgatgca cgagaaaaaa acgatttttt ccctcacatc attagaaaag
      181 aaaacacgag agaagaaaga gcaagcagaa gaaaaaaaaa aaacccagaa aaaaaaaatc
      241 ggcattgatt tttccttcgt gcgggggttc gaccaacaca agtttgggcg ggaaaaagat
      301 tggtccgact ggggatcgaa cccaggaccc tcgcatatct caagcataaa agctgaagta
      361 taagaacgat gtgataatcc tctacaccac cggaccaagt tagtgcgaaa taatttgcca
      421 acctccaact ctaaaagtct tatacaggat tggcatgtct ccacactact tacctaattc
      481 ttcggacaca acactatttc ctattcatga caggatgctt ttgccatttc atgattaatc
      541 catggagaga gatttttgac taggtattct cttacttgcg aaactgggtt gtctacgatt
      601 atcgtcttat gaactattca aacgttactg gaaatgccga tggctcgggt actaattagg
      661 aggggcttct agtctggggc atgtggttct caatagactt cccatgtcaa ctcaccacat
      721 gggagacttt atgaaactag tattggcaat ttaagacaga gaactttcat ttaatcataa
      781 tgcactacaa ctcctttcgc ttaacctcga aatgtttatc caagaactca aacgtcttct
      841 gcgccaacaa cgcccaggct ccaatcttgg ccgttaaacc accgtcggcg acatcattcg
      901 gcacccaaat ctccttcttg ctgtccggca ccttggtgag tagtctctgg atcttgaatg
      961 tgctgtcatc agcagaagcg tacatctcct gtccggaccc tggtcctgtg ataaatactg
     1021 gacatgtgac cttgtccaag atcttcgtac catcctctgg ctccaaagtg aattgcttga
     1081 atcgtctaaa catgccggtg gccttttcga cacccatgct actcttacct agattgatct
     1141 cccatcctgc ttggaagttt cctcgagcgt gccgatccgt gaacgcgtca aaggttccat
     1201 ctgggaccca accgctatcc catagcttga agaatgcctg ggggacgcga gtcagggaca
     1261 gctcccataa gctgaagaat gggtcgatgg atacgcatgc tttgatgcgg ggatccgttg
     1321 cagcacgaag agcaaaatag ccgccggtag ccgctccagc cattgcaatt ctgcctagat
     1381 caagctccaa agccggctga gaacgagaga gatcgtctag aaaatccaag acctttgctg
     1441 cgacgacctc aaagtctggc ctaagcggga ttttgttttt ctttagaagc agtccttggc
     1501 cgggaccttc taaacaaagg atggcgtatc ctagctgagg acctgtgcct ccgtacaaga
     1561 agtataactc ctcctttgtc gaatcggccc ctgctgcata catgactact ggtattttgc
     1621 caggcactcg cgcgtattgc ggagggagaa ataaataccc cggaagagtg atgccgtcct
     1681 cgtatggaat gtccacagac aggacctcgc cgtccatcaa ttctgttgct ctcttgaagc
     1741 aggcgattga tttgtcggtg aagggaatta ctcttgcatc atcgttgttg aacatatatg
     1801 acgtagcccg gaagtaattg gaagctcgca ggtaggcatt tcttgcaagc accctgtagc
     1861 cggcctttgc agcctcatct gcgattttct gcgcccgctc tgcttgttgc ttccatgccg
     1921 cgtaccaaga ctcggggtca ttctttttga tggtattcag agcactcttg aactctccaa
     1981 catcgcaccc gccgctcgat gcactgccca agatgcgggt cagttcaaaa tcgaacatga
     2041 aagaaggcga aaaggtgaac atggtaaaag cctataacat gtgcgaaaga gtcaagtgag
     2101 atgagtaccc aaagctgaaa attgttgtgg ctcgcaagga agttacttga cgagtgatgc
     2161 aggcggtttt cacacgtgaa aatttccttg ctttttcggc ttcgtaacaa agactgtgat
     2221 tgggtgctga agggctattg cccttaggtt tcgatatata ctccttctgg agctttgctt
     2281 atgcatctgg cgaatttggt cttgcaggat gcccgaccga aggcataact tgtaagattc
     2341 ggagctttca agatcgggac tttcataatt cggcacattt gttgtcattt tgatttccat
     2401 taagttgaat caactttgtc agttcataaa cttgactcga ggaattatcg tgacgggtaa
     2461 tgcaatggat gcaagataca cgagtctcct ggttcggtta gcctatgtca tgcatgttcc
     2521 tgatggattg gactgccgac aaggaaggtg gtaatggcaa gggacatgtg catgcaaaag
     2581 acatgaaatt agaggaattc tgtctccgtt gagtttcgga ggtgcgtctt tggagaaact
     2641 tggtatcaag ttacggtgta gtggtgcgac ggatgctatc aatccttatc acttggctta
     2701 ggggtaatgt tgaggcctac aagagtggag caagttgtgc cacctttgaa gatatcgaaa
     2761 aggccaagaa acagccgagt gtgtatgtag gaccaacgcc gttagcggag ggaagtttgg
     2821 ccggacagct acactattac gattgtggcg ttcactcggc agtgttaaag aactcaaaca
     2881 aaacagatcg ccatcagcgg catcattcgt gatgtcatgc tgcgtgagac aagggctggt
     2941 gtgtttcagt gggttcggcg gatttaatag gatctgagca gagggttgtt tacacctgag
     3001 ggaacagggc taaaaggagt tatataatga ctcagctgta agtcacagct tggcgcgata
     3061 aatcacgcac aatggcaatc acgcaacaga ggcatccctg ctaggatgtg gacgcgtttt
     3121 gggctgaaga cattgtattg cgttcccttg catgcatacc gtacgagtat tgtctcgcga
     3181 agtccggcga agatgtgggc atcaccaaac tcccgccacc cttcttctac ttttagagat
     3241 ttaaacgaat agcaatattc tccgaccaac caattccctt ctcatcatag cgcaactgta
     3301 tccatgccag ccgagttccg tgagacaata atcgtcgcac gatatttacg ttcttggcca
     3361 tagtcccctg ggatcgcccg cactaggcgg cccgggggtc gaaggacttc cagatgcgta
     3421 acgtaacttc ttaccttgct tatcaaacgg gcctatggat aaaaggatgc ggttgaaagg
     3481 cgcagagctg ttgtcgaaac gccattcgtc ctcaccgagc gacaaaaggt ccttcgagca
     3541 ccacgccgca aagcaaaagc agtgccgaag cccctgcgga ggcaacgtga ggtggatgag
     3601 catccctgcc caagcgggta tcgtgcaact gcaagagaca ggtcaccgac attttattgg
     3661 ctttgtgcac ataatcctcc cggatatttg cacgtggtat tggacgagag cagccctaac
     3721 atgcaagacg ccaccgttac tcggcataga ttcccggtgt actccgcacg gaatccttcc
     3781 gaatcacccg ggcgacgaaa gcagcggctt tgccattcgc accggtattc gcacacgtag
     3841 ggccagcgtt ttacagcctg aatttgcaag tcattgctgc atcccggctg tattaggaaa
     3901 atgcagaatc ggccgccgga tcgacgctca cgatcgagat gttagtacag tagttcgtag
     3961 acaaagaaga cggaaggcag aaaattgaga gacgatcctg ggagaagaca ttctatatca
     4021 ataccagact gtctcattgc ctcactaata cgtctatttt gggactgact actttagctt
     4081 ccgtcggtaa acgggggctt gtgcggatac tggagcttct tgtgcgaata ttcaggcact
     4141 atccgcaaaa aaagagtgcc gagagagagc tgtatgccgc tactgactcc acagagggag
     4201 gtcagaaatg cacggtcttt ctgtgatctt agctcagctg agatggaata cgggatacgc
     4261 tggcctcggt accgaaggct ggcagcaacg cgtggcgcaa tcgcggttct attggatgcc
     4321 atcctttaaa gggcctcagg aggagagggc cggatagtta gtacttggca cccccccgtt
     4381 ctgcgccgct gaagaccaac actcagcttt ctcctcacag ctctgatcct cctaaacaag
     4441 tccttagctt actgggcaac cagtttttgg cctctaacta agtatggggc ggtcagaaac
     4501 ctcagatcgt ctttccagct ttaaatcaac gtcgggcatt tccaagacac agcagcggca
     4561 ccagcaattt gcatgcgaca gatgcagagg ccagaaactg cgatgtatcc gaacgccgaa
     4621 cgcccataat gcgtgtgaga gatgtcaaaa ggccggtgct acatgcgttg tcgatccgtc
     4681 agtgcgcatg ggacggcctc aacgcggaga caaagaacgg cgggggacgg ccaactcgcg
     4741 aaagtcccag ccggcacatt ccccagaatc tccgaccgcg cggcgaacgt cgtcacataa
     4801 gacatctcaa agtgttgcga ccaacgacag catgtggctg gatcatggct ccgaggacac
     4861 catgggctcg aatctggctg ggacgcaatg cctggactct ctcgacttcg ttctccaggg
     4921 cggcgcgatc gacgatgagc agctgcgaat aactcctcca gaggactgct tcgacgtgaa
     4981 cttcgacttt atatctcctc cggtcccgcg tacaatgcca gatttcggca tatacgagtt
     5041 cggatctgaa gcaacgagcg gatcactgga acctggccca ttcatgccca ttgaacacgc
     5101 ggcaactagt aatccagctg ccgagaaacc aaaccctggc gcccttgtcc atgtttcatc
     5161 gatgcaacaa gaatctgtgg agcagatgtc ggccctaaac gtggaaatac accgacaatt
     5221 gagcgtcgtc agccaagtgg ctaaggaata cgcaaccacc gaacccagtc taatggactc
     5281 aacggaccag agaaaccgtc tctcaagtgc cgttgtctcc atgatacagg ggttgcagac
     5341 gtttcagaca ctgcttctgg agattctcgg tgctgcgcgt cagggctctc ccaaggagcc
     5401 agccagtcgt gcttcgatgc acagctctca gaaaaatgac acatcattgc agacttcttg
     5461 gacttggctt aacacgaaaa atgacctcag cagcattgca gatgccgaca cgggggacac
     5521 tatctcagat ttcgagaccg gagaccgaca gacaatctct cggtccgata cgaactctga
     5581 agttcgaccc attccagaga gcccatctca aaccacttgg ctggatatgt ccacgagcct
     5641 tctgattatt tcctgttaca tcaaccttat acagctttgc cgagacgtct ttgctgctat
     5701 ccggggtgct ctatccgttc caggccacca aacaacactg cttgagctat ctggttttca
     5761 aatcagtggg gtttcaattc atgaagactc tgatcttcaa atcatagttc tcactcaagt
     5821 cgtcgtccgc cttattgata ggattggact ttatctcggc tattctggca cctccacggc
     5881 tgaagccgga aaaagagacg agagtgattt caactgcaaa acaatttcac cacaattact
     5941 agacttcgta cttggacaaa aagaaatgga aggccaaccg tcctgtaaag agcggataga
     6001 ggcgttacga gaggaaatcc ggaaactaag cgaagtcgtt tacaagccga tataaagggg
     6061 gtttgcattc acgagccagg atcatgttgc cacgaagcga ttacgaagcc agatcataaa
     6121 cggggtttct aacttgtccg cattattaag aaatcagata tcaaatcaaa caatatttac
     6181 gtcgcccgaa aggtgaattg tgaacaaaag tgtacattca ggactgaatg attactcgac
     6241 gttgaataac taagcgaagg tgatttttat tgaagacaaa tggccgagca tactatctag
     6301 ggaatatcca aatgaaggtc gacgtgtccc aaggaacagt tgtgattggg cttgtaaaag
     6361 gtttagatag gtgtgtggcg tccctcctaa gtgctgttga ctggtgactc acgtaatcga
     6421 ggcgtaagcc gtccgtgtac cacttgaact tgggtatgac ggaagatggg atgtaccgca
     6481 agactgtctt gtttcaagtt gccatgcatc atcttcggca tgtttcgacc gagagagatg
     6541 acacaacata cgtgttgaca gataagacgg aagtcgtgta actcctttat ctcaccaata
     6601 ttgctgcacc cacggtgctg acaagcaaaa gatgcgggat cgggctttct cccaacttca
     6661 tgtcagagta gaagcccaca cccagaagtc caagggtaaa cttcaacccg aagctccgga
     6721 gctcaggtga ccagagcaga acgcaaactg cgatattaat ggatacaaag acgtatctca
     6781 gagcgctatc ggaaattcct agccaccaga aaaccgcctt gttgtgcagg ggtaacttct
     6841 cctctaggtt cctggagaag gacggtgtga acttggaggt cagatgtgct tggacgcaaa
     6901 gggcactgaa gccgaagatg ccgtaggaca gcacatcgct gagcaacagg gaagacatgg
     6961 tgacgcaagt gaatatcggt ttgccacttg aataatcagc gccgagatat tcggatagtt
     7021 tttttttcgg atagtttttc tgaggcccgt cagcggatac accctttggt ggtggacttg
     7081 catcgacaag cattagactg cgcctcactt acgattgata agctgcggga ttcgccagat
     7141 gcacggggat gggatgctag ttctttctga tcgtaagagg aattttagaa ccaaagcgca
     7201 aattatatgc cctgtcatag agccagtaag accgaaatac cactatagtc cgaatgtctt
     7261 acttagcttc gggcctcaat taataaaccc tccgaacttg acaatgtttg tcgggagttt
     7321 ctgcttactc tctcccctct attccttgcg ggtccatttg catatcgggc ctatggactg
     7381 cctttcaatc cgtatgtgat actcgggact tattgtctca attgcgttcc gtccgagagg
     7441 tggaggatca attgctccgt tgctgactct gtagacatca gaccagtctt acaggccggc
     7501 aaactatcac gatgaaaatc tcaccatatt gtgaatggca atgacgagat ctgcaagtgc
     7561 cgctcggtgt tccccgagcg ctccgtatgg ataaatgatt gtcttttcac gaatgttagt
     7621 attgccactt accacagagt aaactatcaa acattctact gaacaaagca cgatttttca
     7681 gcatttacca actagaaaag agaacctcta agaaaatgtc tcttattcca tcttcaatcc
     7741 gtcttctccg cctccttccg gctctcagct ccacatcggt tctcatgttt gctcttgacg
     7801 agcacctcat ctttggaact tggatgcatc caacactccg cgaacgcgca aacaccactc
     7861 tcccaccgtg gtggactaag ggaggccttc gatggcgctg ggtgatcatc ataggctatc
     7921 ctcttactta cttactgggt atccttaatc tcctggtggc tcgggacgag cttcaggcca
     7981 ccggttcaac tttgtggtac accacgggct tgctgttcag cattgctcat atggcatatg
     8041 taggtacggc cttgaattgg attgcaaata tagagaatgg tatgccgaag ggaaatgtga
     8101 cgtattcgat ggggaactgg ttgaagatga attggactcg ggctctgatt acggacttgc
     8161 cggcctgggt gtgcttcatc accgctgcac tgaaggttct gtagttgaag ctaaaatgac
     8221 tgtaaactag atggtgtgtg ataaagtgaa cagtaataaa aactgccagc gcgcctgagt
     8281 ttgcgataag ttcatgctta agtctctaag agaagaatag cgaatgacga tgcacacccc
     8341 catgcgggtt ggaagtttcg gcttacaata ccaaagggtg cctcaaaatt gatttggttt
     8401 cgatcatatc tttcgtgtag cggcggagct tccacgtacc tcagaattca aattgattta
     8461 gaaaactagc tttgcaaaag ctcaaagttt aagagatacg tgaaattaaa ttgacatatc
     8521 tatgagataa tcagggctcg tagttaaaac agaaatattc aaagtaagaa taatctcaat
     8581 ctcaaagtag tatctagaca agggagacta aaaggagaga atggatgaaa accaccaata
     8641 cgcgtttcaa gccaaggact tccaggcaat gaacaaatag gaaatgataa caaacgaaaa
     8701 caagaaatca ccacaacgcc ttaaaattcg ttttttgacc cgtccgtctt tgagagtagc
     8761 ttctgtccaa tctgcatgcc ctgtcctttg tctatcgaga ggaggaattc gccaaccaaa
     8821 ggattcatac cattttggat ggccttctcc acccaatttt tcatcgatac tgactcccat
     8881 tgaggtccat cgtcggctgt tagaatggtt ttgattgatt gcgctggaat caccttttct
     8941 ccggcatgat gcaagtattc cgcctcggtt gcggtaacgt tgactagtct cccttgcaag
     9001 acagagtcag caatccctgc agccgctttt tcgacggtga taagatcaat gtagcctgtc
     9061 cacttgctgg agtcaggaag cgctttgatc attgcagagt acttgagaac gctaggcaca
     9121 atgtcgtttt cccctgcccc atcaccagtt attgatgagg gacggtggat gaaggttggg
     9181 agaccaaatt gtctcgtcgt tttttctagg aagacttcgc tagcccattt tgaggccgca
     9241 tagccatcga caaaagacgg cccaggaggg tattgtgcta gtgactcagg cgctagagaa
     9301 tccgacttgt tgagctttcc caccgtggcg gtggatatgt aatggatcgg aatatggtga
     9361 gggagagcta gcttgaccaa ctccttggtc gaaagcacgt tggaagctcg tagcgaactg
     9421 tatgttttca agaaagagac atcggcgccg ttgtgaatga tgacattcgc agaaccgaag
     9481 acagaggttg cgtccgcttc ggacagcccg cagcgcggac ttgccagatc tccatcatga
     9541 atgacgactt tcgcggaatt cgtgaaattt gcgagcttct cacggttgcg gatggcaatg
     9601 cagtggatct tgtcgacgtc aggggcttca gtgaggagat tcagcagata ttttccgagg
     9661 aatccagtag cacctgtaag cacgatagtc ttgtgagaac tgtgactttg cgcaggctcc
     9721 tgcgtattaa gctcagaata ggcagacggg acttcagttt caacatccca gttgatctca
     9781 agtttctcgc cgggcgatgt atcttggatg gctgctgcca tggcgccaag tgtactgtgt
     9841 tcgaagaatc gtagcaacgg aagatgaact tggaacctct tcttcacgag ctctcgaagt
     9901 tcaatcagaa gcatcgagtt acctccaacc tggaagaagt cggaagtttc atctatggca
     9961 tagacttctt gcagctgctg gggcaacacc tcaacccaaa tctgggccaa cttggattcg
    10021 gtgtcagtaa gctttctttt tgacctcgtc ttctgttgca atgtgcttgg aatatcaaga
    10081 ttctgaagag cccgtctgtc aattttgcca gatgcattta gcggcatggt agcaatcgga
    10141 atgatcgccg cagggcgcat gtattgtgga agtgggagtg aggcagccag accgcgaaga
    10201 tactctcgct cgttgtcaat cgagacaatc ggcgatacaa cggcatgggc gacaagaatt
    10261 gttgggtctc cgcgaggagt gacaatggcc tcctttactc gtccctcgcc ggccttcagg
    10321 attgattgct caatatcctg catctcaatg cgaagacctc ggagcttgat ctgagtatcc
    10381 ccttcaatgc ggccgaggat ctccagtgta ccatctggtc taagaacacc tttgtcacca
    10441 gtccgataca tcctgttcca gcccctctct atagcggaga cagatgcgaa aggatccttg
    10501 aggaacttct tggcagtctc gacaggattg tttaggtatt caagggccac acctgctccg
    10561 gcaatgcaga tttctcccgg gatctcaatc gtctgaggag ttgcattctc atccacgatg
    10621 taaacagcat agtttggaag agctctgcct gcggttataa attgggcact atgaccatct
    10681 aggttgacct caagctcgtt ggaagacata gagcactctg ttgggccgta ggcgttgaag
    10741 gcgtggaatg aatgagagaa tgcactcttc agtttctgga aagcctgcag aagcttagga
    10801 gtaaacttct caccacctgc cgtagcatat ttccatgatt tgttccggag caggtcgtca
    10861 gagccgtgtc ggagccacgc aaaatattcg gacggggttg cactggtgta ggtaatgttt
    10921 tgttccaaca ggatcttcgc aatagcagac gagtctttgc gaagagactc agggacaata
    10981 acgagactcc ctccgttggc caaggccatg aagacctgat tcatcgacat gtcgaatcct
    11041 acagagctct gctggagaac ggtttcggac ccgaacccat gagtatggac cagagcttcg
    11101 acatggttgc gcaagcttcc atgtgagaga accacaccct tcggaacgcc agtactacca
    11161 ctggtgaaga gaatcgcagc cgggttggcc gctttagtaa acactggact gatggatgct
    11221 gacgctgcag gaagtctcga cacatccaga atggtgacgg atggtgacaa tccgaggctg
    11281 ccgatctgcg acagcgtctt tccatcagcc agcagtgcag aaggcttgca ctctgcgaga
    11341 actaaacgaa gtcgcccttc tggaaggttg cagtccagtg ggacataaat ggcgccgatt
    11401 cggaggacgg cgagcagtga gaagacgaaa ttaggggaag cttcttgata aatcgcgacc
    11461 gttgacccag aagtcacatt ggcttggatc aacacagagg ataccctgtt gatctcttct
    11521 tcgagttgca gataagtcca cgacttgccg gttatttctt tcaaagcaac tttgtcagta
    11581 tgtaccgcaa tcattgcgtc gatgcggtgt acgagagtct ctggccattg agacggcaaa
    11641 acaggaccta cgttcgttta gtacaacgag cttcggtgag aagaaccaaa aactttgttt
    11701 tagtcaggaa agcatacctt gacccaattg gattgaattg ctgatctcct gctcagtgaa
    11761 caaggacacc tcttccagca tctttttaga agagctggaa aggtcattca ggagcttgaa
    11821 gtatagatcc aacactcgag atgactcgtt gtcggaataa agagctttct gaagcatgac
    11881 ggtgacgcgc gtatcgttgc ctgggttttc gatgatgtcc agagagatgt catatccagc
    11941 tctaggaagc gaaagctcct ttgttgcacc ggtggcattg cctagaacgc gcttctcatt
    12001 gacaccctgg cgataattga tgaatgcctg gaagagagga ctgaaagcac tcgaacgctc
    12061 gcaaatgacg ttgtcaagca aaacatcgaa cggcaacctc gagtttgaca ttgcaagata
    12121 agctttcctg cgagtgtcct tgagcatagc ctcaaaagac tgccttccat cgaggtggaa
    12181 tctcagcgga agaagattca ggtacattcc aatgctctga gacacctttt cattccagcg
    12241 gttcgcatct gccatgccaa tgcagacatc gttgttgccg aacagtttga agagcaagac
    12301 ctcgaacaca cccaggtaaa aatggaaaac gtttgccttc agtttgtgac aagtgttcga
    12361 aatctgtctc gcgacccttg gatctacaag gcgactgaca gaagtatgac tataagctgc
    12421 caaagattta cgctgctttt cagctgcaaa gggaagcaga ggaagaggag atggtacgtc
    12481 agcgaattcg gacttccaat agttgatctc ctcttgcatg gtgccctgtt caagctcttg
    12541 gcgtagtttc tccgaataat cagaatattg gtagacctgg ttagaaagac tttgaccatt
    12601 gtatgctttc tcaatgtctt tcaagaaaac ctccaggctg ataccatcca tgatgatgtg
    12661 atgtgatccg atgagaagat aactctccgt atccgtgacc tcaaggtata caagtcgcat
    12721 acattcgcca tgttcaatgt catagacgtg cttcttgaga ccttcgaact cccgctcggc
    12781 ctgagaaccc gaacttagag tcttcttctc aaggtacaga cgggaggttt ccgaaatggc
    12841 ttggataggt ttctggttct catccatgaa gaacgaggta cgtagggctt catggcgagc
    12901 agcaaccttt cgtatagcca tttcgagatc gttcagccta attgtacctt gaattgagac
    12961 ccagatggtg ttgtttgccg tagtttgatc ttccagtagg tgcttgagga accagaatct
    13021 cgactgaccc ggggatacag gcagaacctt ttcgtaagtc aattctgaga tatcgttgac
    13081 cgactcagag ggtgattctt ctttcttgtc ttgcgcgtca ccctgttcac tagtcttgga
    13141 gcttccctca ctcatctgct ggctactacc tgaggcacta gtctttggta gactgcttgg
    13201 cgacgaagag actgaatctg gtggtggcat caatgtggct ggggcttctg gttccggttc
    13261 agatgccttc gccgagtctg ctcgattcgg ggttagttct gcgggcatgc tcccaatggc
    13321 atactcgaca agctgtgtta cggaacctcc ggacaggact ttgaacacgg ggatctcagt
    13381 ctctagctcc ttcagaaacc aggaccgtat ttcaacggcg accaaagaat caatgccaag
    13441 gtcatccgtt cctgaagcga ggacttgaga tttatcagtc tcgtctggaa tctgaagtgc
    13501 gacctgaagt ttcaggtaaa aggcgtctat ttcgtcgtca ggtgacttga ccagccattg
    13561 caaattacga tgaacttacc ttgaacaatc tcaagaatct cttctgccgt agttgcctcg
    13621 gcaagtttga gcttcgtaga gacagcagct gtcttcttct ttgccctttt gtttgcgcca
    13681 tcgtcagctt gaagacagtg ttggaaccga ggaaattttg tccacagggg aggcttgtcg
    13741 ccgagcctag atagctccaa cgccgtaatc acttccgggt tccgtccaga atggggatta
    13801 gatgcaagaa ctgcttcacc gaaaagaaga tgaagccctc gctctgacat catcatgaag
    13861 ccggcccttc tgagagtagt gaagaaagca tccgagaatc ctcggttgat gtaccctaca
    13921 cccatgaccg caccgaggtg aagaatcgaa gctgccaaac ctttatcccg cctctggctc
    13981 gccaacgaag tcatgaacat gttggcgctg gtgtaagcag attgcccacg attcccagct
    14041 atagctgtaa cggaagagaa gaagacgaag aagtcaaggc tagtgtcctg gaaaatttca
    14101 tccaaaagaa tagctccttg aaccttcggc ccaaggactt tagtcatctt ctcataaggc
    14161 atctcgaaga atgacacgtc atccagaacc atagcaccat gcgcgacacc cgcgattgga
    14221 gggaagttct tgcgtatgtg gtgaacaagg gaagacaaag catctttgtt ggttatatcg
    14281 ctttaaaata gtcagctttc tcataataca ggacaacagg atgtcaatct cactttgcaa
    14341 aagcctccaa tctgaccccg gcccctttca ggagctctat ccagttggaa tcaatctttg
    14401 gattgcgact cgtgagtacg atgttccgcg ccccacgaga caccatccag tcacagatag
    14461 actgggccaa gtcactcgtc agtccaaaca ggacgtatgt gttgttgccc ttaaacgtga
    14521 catggttatc aaccgtggat acctggacag gaacgctcgt tgcggtgctc caatccacca
    14581 ctgcttgcgt agtggatgcg actgcagaat cgtcgatcag ggtttccaac ttgatcgaag
    14641 gtagtgtacc tggattgctt ggggcggcaa gctctttcga agcccatgca agagcatcat
    14701 tcagtttttg acacaagtca gtaggggata gacctctgat tctttgcagt gattgaaccc
    14761 cagagattgt cgtttgaaaa catgatggaa gcagacaaga tgcgatcaac gacgctgtcc
    14821 tccggctctg gctgcccgca gagcagtcaa tgaagactga cacattttca ggcaataaag
    14881 accgaatagc tctctgagta gagtatgcat caattcttgt ccatgtgcta tcgccggaag
    14941 aagtggaagt ggtgaaaacg acattgatct tcccacttga accacacgca gcaatggctg
    15001 atgcaaggtc cggagacggc tcatgaatga gcaaggtgga gtcgctctca catagtgaca
    15061 gcatgctgtc gacttgtagc cgagtgttga agagagacaa caactgggac tcctggcccg
    15121 caggaacgtc aatggctagc accttgtttg aagctactag agcatacgac ccattgttat
    15181 ccgcaatgga caagaccgac ttcttcgttt tgttgatagt accgaggatc aggtacaatg
    15241 gagtcggcgc tgcaagtgcg ggcattaaca gtgagtgtgt gactttgatg agtgtctcgg
    15301 agtcgtcctt gagttcccat gagctcagcg tcttagccac gagaacgtcg tccaaaacca
    15361 aaaattgctt cagcgatggg ccaagggaga ggttaagcgg agtctcttgt ggatttttcg
    15421 cttcgaggac cgttcgtttg gctgcattgt atctgtcgtt gagtgcgcca ctaagatgaa
    15481 ctcgagatag cgtgagatct cccttgtcat aggcgagctc atgctcattc gtccacaaga
    15541 cgtcatcgaa ttttccttct ttctcccata tgtcgctttg tcgcaggcgc agtaatactt
    15601 ctagaagttg tcggggattt ggttcgacac caggttcaag gtcaaggaac tgcaaagcca
    15661 gatcgggatt ctccagaacc aaggtccgcc caagcccaac tgacatgttc atccaagggt
    15721 cttccgatct gcagccttgg gtgatccaga gaactgttct ttgcgtttcg aaaagccttt
    15781 gcaagccctc gagtgtcgta cttgatagac ctttgaacac tggctcatct aggtccgcca
    15841 ggcacaggat agctgttgta ggggatattc tcgtgccgtc gacctcgtcg atagtcttga
    15901 agactgagtg agttacgcct gatgacgtga tgagtcctga gatttgctcg atgatcatcg
    15961 ctgtttttga tgtctgaccg ccgacaagta ccaagtccca aggctcgccc acagatgcgt
    16021 cgttttgaac cagagaaaga ggttcgcgga gtagggctat acggtcatcg actgcctgag
    16081 aaacaatgac agctagtggg taaggcgctg cgtcgtactc gggcatgggg gagtctgcgc
    16141 cggagaaccc tgtttcgagg agcaggttgt gccactcaga cgtcgacaca cagggcgaca
    16201 acttcctgcc atcatcttgg ccaagccacc agcccggaac agcgcaaatg aggaacccga
    16261 ctctggcaat gtcgttgtcg caaatctcct ggaagatgag gtaaccacca ggcttcaaga
    16321 gccggcgggc gtttgtcaag gtcctcttga gattggtagt cgcgtgtaga accaacgaag
    16381 caacgacgag gtcataagaa tgttcttcaa agctttgctc cgtgatgtct ttttccacat
    16441 cgagagtctt gaagatcatc ttgtccgcga cggcagagaa tacttcttgt gcagattcga
    16501 agaaattggg agagatatcg gtataggtgt atgaggagaa cgaacgaccg atacccctca
    16561 tgatgacttt tgtggcgcca cccgttccag ctcctataat aaggttagca gatatctctg
    16621 aagtcaactt aaatacactt gcctatttca aggatcttca tgcgcggatg gcgatggacg
    16681 acttgctcta caatctttcc aaggtagccc gagacctctt tcaggcctaa cccaacctca
    16741 tagaagcgat taagcaggtt gtctttggtt aagtgttgca ggattgttga ttctcctcga
    16801 agcacagctg gcagattgtc acccacggcg caagtgagct gcatgtcaac cgtgtgtgcg
    16861 tatctgaata tctgtcatta ccttgactat agtatgaaaa tttggtggag cttacctggc
    16921 cttgatgcct tccacatccg cagcagtatc ctgaagccac tccctccgag cagttcgcct
    16981 ctctccagct tcgagagtcg tcaggacgtc agtgaagaac gcaaacatgc attcaaagtg
    17041 ccattccaaa ttcatgatct tgcgaagcga ttcagggaaa agagtgacca gctgcttcat
    17101 gtagtataca accactcgct ccatgccgta tgcaaactcg tagtcttgaa gagtcgcgcg
    17161 cttgccgccc atagcacgct cgcagttggg ggccaacaca tcccagacat gttcagagaa
    17221 aatggcacgg tctgcgtctt cagtctgctc agcaaaggcg acaaccctca agccttccat
    17281 ttgaaccaga ccagctccgt cgtcagcgta gatctccacg tctccgttga gatgttttgt
    17341 agcgagaggg tttccagtca actgggtaca agaggaaaca tcggtttcag gagtaaggac
    17401 ttgctgacaa aggccgacgt tgacgcggaa gttcttgatc ccagtaggaa catgaagctg
    17461 ctcaagacta ccatcgcctg gccagcaata agccaagaag atgccttgta aagcggtatc
    17521 aaggagtgct ggatggagca gcatcttctc gggttcgtca tcctgtggag gtactctgat
    17581 cttagtggat gagaagttca gccttctctt gatggacgac atcgtcttga aatatccact
    17641 atatgcgtaa cctaaaggct ccagggaagc atagaaacgg tcctctggga tgtcgacaag
    17701 atttggaaga tctttttgtc gtgatgggag ccagtgtgaa gaggtttcgc ctgtaatgac
    17761 aatgactctt ccaatggcat gggtggacaa ctgttcagtc tctgcattgg tagatgcgtg
    17821 atagatgaag gaagcggagt aggttgtgtc attctcctta gcaatatcgc tgagtgtgaa
    17881 gacggtttcg ataccagcag catcctctgc aaagacgaga ggcttaccaa gactaaagtc
    17941 ctccacttca atcaaggcaa tgttgtcgcc tttaggaacc aagaacctag cagcttccac
    18001 tgcagtagat atatacgccg tggccgggta gatgacctgt ccttgaagct gatgacctct
    18061 gacccaagga agctcactca gccggagcag attcctccat cttatttctt gctccattac
    18121 atctgttgtt ctggatccaa gcagaggatt tgggatgttc ttctggccga ggaaagcctt
    18181 cactgcgcga gacttgtgcc agaatatttt gtcgtggtcc caatgatatg taggcaaatt
    18241 tcggatcagg cttctctgtt cgcctccaga ggccagcaaa tcaaatcctc ggaagtcgat
    18301 aagcgagggt gtaaattgtg tccagaggta gcccaaggca tcagagagag cttcaatatc
    18361 gtctttgccc cgattcaaaa gacccgtgta tggaatggtg tctttctgga cctcctgaag
    18421 cgtttggaga gcaggtccct tcagtgccgg atgaggaccg acctcgattg caatatcgaa
    18481 tgcatcccca gcagatgcag cagcctcaac agcatgtgag aacagtactg gctggatcat
    18541 gttgtctgcc cagtattgtc ctgctagagc cccatcccca tggctatatt tgttcttgtg
    18601 cgtactcgaa tgccagacgc agtcatcagt tcccgataga gggtgaatct cggagttctt
    18661 cagtgcctca agatagccct ctgcacaagg aaccatgtgt gaggagtggt atgccttgtc
    18721 gaccttgaga agccttgcga acttcttctc atcttcaagc acttccttgg cttgctcgat
    18781 agcatcacga tctcctgaaa ttgtaacact ggacgatgaa ttgacagcag ccacagccaa
    18841 gcggccttgg aacatgggga ggctgcaaag ctcttcagca tcctccgcgg acgtgccgat
    18901 agccatcatg gcaccaggcc ggtcggatgg tgtcagattg gtaaaatagc ctctgtagta
    18961 ggcaattttg agggcgtctt ctcgagtgag gtatcctgca gcgtatgcgg cagcaatctc
    19021 tcctgatgag tggccaacaa ctgcttgcaa cttgacacca gcgctactca atagatcaaa
    19081 gagtatgatt tgaacaacag tgcatagcgg ttgtgcaata acggccgtgt tgagccgaga
    19141 ctgagaagca tcacacgtga gttcatacat gagtgaccaa tccggccgct ctggctcagg
    19201 taagctttgc agaaccagat ccaatttctg gacaacttct tttgcgtatg gggagttgag
    19261 gaccagctcc ctccccatag acggccattg cgccccctga ccagtgaaaa cacccaatgc
    19321 gcggactggt cttgaaagta ttttcgaacg ggttccaata ctttgagcat tgccaccact
    19381 ggacggcacc tggagaagat cgtcaatcct cgtatagagg tctgtagtcg atcccgccga
    19441 tatatgtact cgcacagcgt gttcgcttct ccgagcataa agtgtatagg agaggtcttg
    19501 cagcgagact tcgggattca gccgaaggta gttggaatag tcggtcaaaa tgcctctcaa
    19561 ggacttctct gaggcggcag agaagttaaa aggtgtgaat tgacgagtag taatggctcg
    19621 atcggtatgt gcgggtgaag ggatgtagtt ctcgatgata caatgcgcgt tagtacctcc
    19681 aaatccgaaa ctattgatac tggcacgtct tggggtcccc tctgcaagct ttggccaggg
    19741 tctaggactc gtcaacacct caagattggt gtagaagggc tctacagccg gactcagctg
    19801 attgaagagc aagttgggcg ggacgattcc gtgctggacg gcgagtgagg ctttgagaag
    19861 accagccaac ccggcagttc cctcggtgtg accaattacg gtcttgatgg agccgacata
    19921 aagcggatca gttttcccag aaatatcctc gccgggatga aagaaggctt tgctaatggc
    19981 ttcagcctcc tacgaatatc gacgttagaa tgagactcgc gcttattcgt gtggcaattc
    20041 ttaccttggg gtcaccagct gcagttccag tcccgtgggc ttcgaagtac tggcagcgtt
    20101 cagtcgggtc tctagggttt agaccagctt tcgcataggt cctggaaatc agatcggctt
    20161 gcgctactga gctaggcata gtgatgcctt ttgttcggcc gtcttggtta atgcctgact
    20221 cgcgaatgat gcactcaatt tggtctccgt ccgcaattgc agagctcaac cgcttcagga
    20281 ccacggcagc aactccttca ccgcgagcat acccggaagc gtcaatatcc cacattcggg
    20341 agcgactgtt tgacgacagc atttgtagct tgctctccgc aatgtacgga agaggcccaa
    20401 gcatcaggtt agctccagcg gctaccgcga catctgagtc accactacgc agcaactgaa
    20461 cagcctggtg cactgctacc aaactggagg agcatgccgt atcaatagtc atgctcggac
    20521 catgccaatc gaagaagtac gaaatacggt tcgacatgat acttcgcgcg gttcctgtcg
    20581 gggtgtaggt aggcagcgag ttcacatcgt tattcaagag atcgacgtag tcggcgcaca
    20641 tcagcccgac gtacactccg gtccgagacc cagctaatga ctccattgat aatccagctg
    20701 cttcgagaga ctcgtatacc gcttccatca aaatgcgttg ctgtggatca atggcatgga
    20761 cttctacagg cttgatattg aagaaggctg catcgaactg ccggtgatcc tcttcgagga
    20821 aataggattc ccggacgtct gatgttccgt ggtgaaatgg ctttggatga tagaaagcat
    20881 ctgagttgaa gcggttctcg ggtattttag tcagaagatc tcgtggctta accaagagat
    20941 cccaaagctt tgaggggttg ttcgatgagc cgggaaatcg aaacccgctt ccaacaaccg
    21001 caatgggctc tctctggccg ctctctttaa caggatcctg accactcata atgatgattg
    21061 caaatggttt cgttacgttg ctgaaacttg atggaatcgg gtgcttggga aataacgagt
    21121 ggacggtgtg tagagcaggg cagatcgttt attgtcaaga taatgttgac atataatttg
    21181 aagcccctga tacatactga gcagagatac tgatttccta atctatcagg attccatcgg
    21241 aaactcggaa taaattgact tcggagcttg aagtgcatta ttcgtggcgg tgctgaagga
    21301 ggtcgggatt ttgttccagc ctatcaaagg cccaagttcg gaggtttgtc tgaggacaaa
    21361 atcccgaaga ccgtcttcag ccgcacgggg gatcccggtt attatccagg ttatgttgat
    21421 cggtgatttt ggaaagagaa gcccatattg gtattttcgc ctggaaagca ttttgcattc
    21481 ggcagatggg cctccttttt gcttattcca tggtcctata attggattta gctattgaag
    21541 actattggcg agcgtcctgt ccctatgtcg gatagagaaa agccgacaaa agattagcaa
    21601 ctaacgttcc gatcgcggtt cccctcttac agggctatag atggaataaa agaaattcag
    21661 atgcacaaca gaaaggaaat catggcaggc ccgtggaaat aaagaattgt catgaagtat
    21721 ccagattatg tatgccaaga aaaccaagtt gcattgaatt gcataatacc taatcttctt
    21781 gatagtcact acaatacgta cccaaccaac ttcataacat acgtctttcc tcttcctagg
    21841 aatccaagac cccaaacaag ccatatcttc cactcctcga tatgctctgg ccagtaggtt
    21901 tgttctgatt gacctttccc ttcgtactgt acacctccga cctcaccacc aactacccgg
    21961 ttagcgaagc cgctcatgcc aaacccagct ccagcaccta tttcatactg agtcacaata
    22021 tgttgcacgt cgaatgtcca tttcttgtct ctagcgggtg aggcgaattc cagatggtgg
    22081 ccagtgttct tgtccttgta cttccctgac atctccccgt cgaattggtc attaaacagg
    22141 acgtaatcag ccttgtcgga aggttggcca actctagaac caaccaagag ttcatcgtgg
    22201 taaaacaggt gccccgagac atatcgtaca cctctgtcta tgcgtgaaag cacatcccag
    22261 tatacgatag aataaggtcc cgcccaggct cgaatcactt tccagccatc acagagctta
    22321 agccagcctt ccgtagccca aagacgagta gaacctcctc tacctttaaa cgttatccgt
    22381 tttccagatg acagagtagc gtcgacgtcg acctcggctc ctcccataga tagtccatag
    22441 aacaagccag gagagacctc agtagcatct ggtttcccgc catcgggtgt ccagggcgag
    22501 ccgtccgcta ggtgaggcct tgtacttgaa gacatggtga agccacctcg aactctccac
    22561 gagtcaaact tcagtctcgc aaactgatga tccttggtga catagaacga atatgacctg
    22621 tctgtactat tccagattcc cgcggtaaag tccgggcaat caatgacgta agattcactg
    22681 atgaagtcca gctcttgaat tattgagccg tccccaagag tgatgtagaa ttccacgcgt
    22741 aaatttccct ggccaaagaa ggcgtacgtc gcatctctgg agaatgccat cagcagtcca
    22801 gataggccag tgtgcgacag accatcaaat tcccattgtt cccaattggt cgcgttgaca
    22861 tgaggtgata ttttgactga gtgtatgtcc tcagatgggg acgaagagaa ggtattgggg
    22921 ccatcgtgta cgtcatacgc agtgctcttg ctgatcgaac aagaatcgtc ccattcttca
    22981 ttcaaatatt caggaaattg tggattgaga ggcacttgag attcatacgc cgatacgaca
    23041 gcagaaacga gtgctgtcag tgtaagagtt ctgaacatat ttgccgcggg gctcatcatg
    23101 aagggtgtgg tggtatgatt taacgcgtcg gatcaggctg gaggatggaa agccgcaggg
    23161 aaataagaaa ccaactaaca tagttcagag tgtctagata agccagagtt actgttatag
    23221 aagtcccgaa atgccatcca agttatatgt gtggagagac ggctttgaga aagtcccgag
    23281 ctaatatgtc aaattcccga atgtcggttg cagcacgaaa atccttcatc ctcggtctcc
    23341 gatggctact ataggatgaa atatgtggta accgggtggc atttctgcaa aaccggaata
    23401 gaaatgttaa gaaggatact caaagtcgaa agttgaagtg ctccaagtca tacgacaccc
    23461 tccgtcctat cgctgcaatg gcgagcactg gtcttccaca acttcctcct tcgcaaaagg
    23521 cggttattca gtctgagaag actcctggcg catttgaagt gtctgagaat agaccggtcc
    23581 cggtcccgaa ggccaatgaa cttattgtca aagtatcagc ggtgtcgttg aatcattgcg
    23641 actggaagat gcccggccgt gttccctgcc ctggagcagt tgatggggcc gattattcgg
    23701 gaactatcgt acggatgggc gaaattgcgg ctctcaaatc aggttttcag atcggagatc
    23761 gggttgcagg cgctcagatg gcctccagtc gtcgtcgccc ttgggcggga gctttcaccg
    23821 aatatctgag agatgagtac gacatggttt ggaaggtacc agacaacctc tcctgggagc
    23881 aagcggctgc aatagggtgt gcgacaacta gtactgtggg aatggcgctc tggatttcga
    23941 tgaagctacc cggaacgccc gagaacccga ttaaggagcc gaaacttgtc cttgtttacg
    24001 gcggttccac tgccagcggc acgtttgcta tccaattgct caagctgtaa gcgatgacct
    24061 ttaccttgtg attgaaaata tcagaagctt atacttgaat aggtctggct acaaggtcgt
    24121 cactacatgt tcccccaaaa acttcaagct cgtagaagag tatggcgccg acaaggcctt
    24181 tgactatcac tctgcaacat gtggagagga cattcgtgca tataccaaca acaccttgga
    24241 gtatgctctc gatatcatca cggaagctcg aactatccgg cattgctatg ctgctattgg
    24301 acgaggaggt ggcaggtatt gcgggttcga actgctgccg gaagacctaa ttgccacaat
    24361 gcgaaagtcg gtcaaggccg aatgggttat gggactcgaa atgactggcc tagaaatcga
    24421 tttgccggga gggtactatc gcaaagccaa cccggagctg catacttggt tttgtgactg
    24481 gaaagaacgc tatgtggctc tgtttgggtc gggtaagacc aagacacatc cgatcacggt
    24541 gaggcaaggg ggactagaaa aggtcattga cggaattgag tccatgcggc gaagagaagt
    24601 ttcgggtgag aagattgtat acccgttata cataaaaggc tgctaaggct ctagtcttca
    24661 catcagtact gaggatggat acacgcccca agtagagaca ttagcaagca cttcatcgca
    24721 aagctttggt atcgagacct cggagagtac ccttatatcc gctttaagag ccatttttat
    24781 tgaataacca aattaggtaa tcgtttataa tgaaccccgt ttgaagtatt gaccagaaaa
    24841 gacgtaatgg ttgcatgcgt cttaagtgtc cgtgggtcga ggcccaatat agtcatacac
    24901 taatctcagt ctcacaacat cgttgcctct cttcaccaca atatgccttg tatgaaacct
    24961 tgtgccatta atctcctcga acccgaaggc ctgatgtgtc acagcatcga tgtcgagatg
    25021 ttcggacatc atgtggacaa cggaatttgg tccttcttca aatccttttg ccaggtactc
    25081 gtctatttca tcaagctctt tggctgatgc ccagcgcatt gaaactcgta gtttcccgta
    25141 gaacgggacg gttagctcgt cgccctcaaa gttcagtgtt cgctgctcgg agctgctcgg
    25201 caaacctagg gggggtttat attccataag gacgcttgtc aggccggttt gaccatctgg
    25261 ccatgttttg atggctactg ataccgatac caagttaata atccttcgca tgagccaagg
//
