LOCUS       BGC0002512             24923 bp    DNA     linear   BCT 01-SEP-2020
DEFINITION  Brasilonema sp. CT11 apt gene cluster, complete sequence.
ACCESSION   BGC0002512
VERSION     BGC0002512
KEYWORDS    .
SOURCE      Brasilonema sp. CT11
  ORGANISM  Brasilonema sp. CT11
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Scytonemataceae; Brasilonema.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:52:57
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..6606
                     /gene="aptA"
     CDS             1..6606
                     /NRPS_PKS="Domain: AMP-binding (46-449). E-value: 1.9e-116.
                     Score: 380.8. Matches aSDomain:
                     nrpspksdomains_aptA_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (566-635). E-value: 9.5e-26. Score:
                     81.7. Matches aSDomain: nrpspksdomains_aptA_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (654-953). E-value:
                     2.2e-102. Score: 333.9. Matches aSDomain:
                     nrpspksdomains_aptA_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1130-1537). E-value:
                     3.5e-116. Score: 380.0. Matches aSDomain:
                     nrpspksdomains_aptA_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1645-1710). E-value: 2.5e-25.
                     Score: 80.3. Matches aSDomain: nrpspksdomains_aptA_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1723-2030). E-value:
                     5.3e-157. Score: 515.7. Matches aSDomain:
                     nrpspksdomains_aptA_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2035-2188). E-value: 7.2e-47.
                     Score: 150.9. Matches aSDomain:
                     nrpspksdomains_aptA_TIGR01720.1"
                     /NRPS_PKS="Domain: NRPS-COM_Cterm (2172-2193). E-value:
                     3e-09. Score: 28.4. Matches aSDomain:
                     nrpspksdomains_aptA_NRPS-COM_Cterm.1"
                     /codon_start=1
                     /gene="aptA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     382.4; E-value: 4.3e-116)"
                     /gene_kind="biosynthetic"
                     /note="nonribosomal peptide synthetase"
                     /product="AptA"
                     /protein_id="QNL14922.1"
                     /sec_met_domain="PP-binding (E-value: 6.3e-18, bitscore:
                     53.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 7.7e-71, bitscore:
                     227.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.4e-129, bitscore:
                     418.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQENLVSSTHYINDFYALTEQEQYKILVEWNDTTVDYPKDFCIHQ
                     LFEAQVEKTPDNIAVVFNEQKFTYQELNHRANKVAHYLQFLGVGTEVLVGICVDRSLEM
                     IVGMLGILKAGGAYVPLDPTYPQERLSFMLSDSQVQVLLTQQKFVAEFTESGVKTVCLD
                     TDWEFINHQSQENPTSDATAENLAYVIYTSGSTGTPKGVAVPHRAVNRLVCNTNYVQLD
                     KSDAYGGKLRIAQASNASFDAATFEIWGSLLHGARLVIIPQNVVLSPHHFAACIREQGI
                     SVLFLTTALFNQLAGVVPQAFKDLRYLLIGGDALDPKSVKTVLRNGPPQRLINGYGPTE
                     STTFSCWYLVEEVAEGATNLPIGRPISNTQIYILNSKLQPVPIGTTGELYIGGDGLARG
                     YLNRPDLTEEKFIPNPFGNSKLYKTGDLARYLPDGNIEFIGRVDNQVKIRGFRIELLEI
                     EAVLSQHPDVSQAVVVAREEIPGDKRLVAYIVLNQKSEAMPAAGFAYATTLKSFLEAKL
                     PNYMVPATFMILDTLPLTPNGKVDRRNLPAPDRSRPDLEATFVAPRNSIEEKLEIIWAE
                     LLRLEQIGVNDNFFHLGGHSLIATQMLSRVREVFQVELSFHQIFENPTIGSLAQLIAQG
                     HKEQQWQHPAIERIPHEGLLPVSFAQERVYFIQQLACESNAYQFQATMRFRGWLDVTVL
                     QKCLNEIVLRHEIFRTTYPAVNGKLFQVINPHQPISFTVIDLQSFPEYEREAEAQKLIE
                     IEVQKPFDMNQLPLVRWVLLKLSDQEHLLIHIEHHMAHDGWSFNVFLGELVELYQAFCL
                     DHPSPLPEPLLQFADFAHWQREWVNTAEAQAQLAYWQQKLSGSSPLLELPTDRPRPIEQ
                     TYQGDQIRMELPIDLCESLRVLSRREGVTLFMTMLAVFLVMLHRYTGQDDINVGTAVAN
                     RRMHEIEKLIGMIVNNLVLRTDLSGNPTFRELLGRVRSCTMEAYANEDLPFDKVVEVLK
                     PIRNLSHNPLFQVMFSFHDSPMPDLSLPGLDISLHEPISNKSAKFDLDFLVIPRLEQRV
                     QNGSKTGAKGITLVLEYNSDLFDAATIQRMLEQYQNLLYKIVANPEQHIGELPLLTQGQ
                     QQLLVTWNSTHREYPERECIYQLFAAQVELTPNAIAVEQDGQRLTYRELSDRTNQLAHY
                     LQSLAVKPETLVGICVDRSLEMIVGLLGILKAGGAYVPLDPAYPKQRLADILADTQLGI
                     LLTQERFRSQLPDYTGKTICLDTDWKVIAQNSTANPISDVQLHNLAYIIYTSGSTGKPK
                     GVMIEHRSLFNFVMTAIHEYEINATDRILQFASICFDTSIEEIFPCLCVGATLVLRTEQ
                     MLHSSDEFWRCCQKWELTILDLPTAYWHQLVTELNPQDGRIPASLKTVIIGGEEVQLEK
                     VKHWHSCVAHIPHLPQLFNSYGPTEATVITTLHYLNSSAVTSVSIGRPISNAQVYVLDQ
                     YLQPVPVGVPGELHIGGVSLARGYWQRPELTAEKFIQNPIPYATCDRLYKTGDLGRFRA
                     DGTLEYLGRVDDQVKIRGFRIELGEIETVLRQHPQVRQAVVIARVDIPGQKRLVAYVVP
                     HQPQPTTDELRYFLKQKLPNYMVPSAFVLLEALPMTPNRKVDYRVLPVPDFSRSVEDKF
                     LAPRTLTEEKLTAIWSEILRLEKVGIHDNFFELGGDSILSIQIISRANQAGIQIAPKQL
                     FKYQTIAELAAVAGITRSVKAELGLVTGQVMLTPIQQWFFEQKLSEPHYFNQSALLEVL
                     PDFKSEQLQQVVQQLLQHHDALRLRFVQEGENWQQINAATQESLPLSVIDLSHLSPEEQ
                     QTAMKAADAELQASLDLSTGAIARIALFQLGKNQPGRLLLIIHHLAVDGISWRILLEDL
                     ATAYEQISRGDAIKLPPKTTSFQYWSDRLTEYGRSEAIATELDYWLSEYNFKVTALPVD
                     YPSNKEDNTVASTACMSLSLTEEQTRALLQDVPSAYNTQINDVLLTALVQSFSQWTGER
                     SLLIDLEGHGREDLFEDVDLSRTVGWFTTLFPVRLQLEEGDDPGEALKLVKEQLRGIPN
                     RGIGYGVLRYLNENAAIRTKLQALPQAQVSFNYLGQFDQVLKASDVLGLAKEFKAEQSL
                     LNKRSHLLGISGLIRAEKLEMTWSYSEKVHQRTTIERLALGFMEALKTLIAHCQSPDAI
                     SHTPSDFSAAKLSQKQLDKFLAKINKNKTKKR"
     source          1..24923
                     /collected_by="Jan Mares"
                     /collection_date="2010-03-18"
                     /db_xref="taxon:2748322"
                     /isolate="CR6-5A/2"
                     /isolation_source="Costa Rica: Uvita, pacific beach, bamboo
                     forest, black mat on a bamboo trunk"
                     /mol_type="genomic DNA"
                     /organism="Brasilonema sp. CT11"
                     /strain="CT11"
     misc_feature    1..24923
                     /note="apt gene cluster"
     protocluster    1..24923
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:22653]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..22653
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..24923
                     /SMILES="NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC([*])
                     C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..24923
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002512"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24923
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        139..1347
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_AMP-binding.1"
                     /evalue="1.90E-116"
                     /label="aptA_AMP-binding.1"
                     /locus_tag="aptA"
                     /protein_end="449"
                     /protein_start="46"
                     /score="380.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEAQVEKTPDNIAVVFNEQKFTYQELNHRANKVAHYLQFLGVGTE
                     VLVGICVDRSLEMIVGMLGILKAGGAYVPLDPTYPQERLSFMLSDSQVQVLLTQQKFVA
                     EFTESGVKTVCLDTDWEFINHQSQENPTSDATAENLAYVIYTSGSTGTPKGVAVPHRAV
                     NRLVCNTNYVQLDKSDAYGGKLRIAQASNASFDAATFEIWGSLLHGARLVIIPQNVVLS
                     PHHFAACIREQGISVLFLTTALFNQLAGVVPQAFKDLRYLLIGGDALDPKSVKTVLRNG
                     PPQRLINGYGPTESTTFSCWYLVEEVAEGATNLPIGRPISNTQIYILNSKLQPVPIGTT
                     GELYIGGDGLARGYLNRPDLTEEKFIPNPFGNSKLYKTGDLARYLPDGNIEFIGRVDNQ
                     VKIR"
     aSModule        139..1905
                     /complete
                     /domains="nrpspksdomains_aptA_AMP-binding.1"
                     /domains="nrpspksdomains_aptA_PCP.1"
                     /locus_tags="aptA"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       325..366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0001"
                     /evalue="7.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="aptA"
                     /protein_end="122"
                     /protein_start="108"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       559..618
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0002"
                     /evalue="3.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="aptA"
                     /protein_end="206"
                     /protein_start="186"
                     /score="31.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVAVPH"
     CDS_motif       1006..1029
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0003"
                     /evalue="4.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="aptA"
                     /protein_end="343"
                     /protein_start="335"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPTESTT"
     CDS_motif       1144..1233
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0004"
                     /evalue="5.50E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="aptA"
                     /protein_end="411"
                     /protein_start="381"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PIGTTGELYIGGDGLARGYLNRPDLTEEKF"
     CDS_motif       1312..1377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0005"
                     /evalue="6.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="aptA"
                     /protein_end="459"
                     /protein_start="437"
                     /score="34.2"
                     /tool="antismash"
                     /translation="FIGRVDNQVKIRGFRIELLEIE"
     aSDomain        1699..1905
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_PCP.1"
                     /evalue="9.50E-26"
                     /label="aptA_PCP.1"
                     /locus_tag="aptA"
                     /protein_end="635"
                     /protein_start="566"
                     /score="81.7"
                     /tool="antismash"
                     /translation="EEKLEIIWAELLRLEQIGVNDNFFHLGGHSLIATQMLSRVREVFQ
                     VELSFHQIFENPTIGSLAQLIAQG"
     aSDomain        1963..2859
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.20E-102"
                     /label="aptA_Condensation_LCL.1"
                     /locus_tag="aptA"
                     /protein_end="953"
                     /protein_start="654"
                     /score="333.9"
                     /tool="antismash"
                     /translation="LPVSFAQERVYFIQQLACESNAYQFQATMRFRGWLDVTVLQKCLN
                     EIVLRHEIFRTTYPAVNGKLFQVINPHQPISFTVIDLQSFPEYEREAEAQKLIEIEVQK
                     PFDMNQLPLVRWVLLKLSDQEHLLIHIEHHMAHDGWSFNVFLGELVELYQAFCLDHPSP
                     LPEPLLQFADFAHWQREWVNTAEAQAQLAYWQQKLSGSSPLLELPTDRPRPIEQTYQGD
                     QIRMELPIDLCESLRVLSRREGVTLFMTMLAVFLVMLHRYTGQDDINVGTAVANRRMHE
                     IEKLIGMIVNNLVLRTDL"
     aSModule        1963..6564
                     /complete
                     /domains="nrpspksdomains_aptA_Condensation_LCL.1"
                     /domains="nrpspksdomains_aptA_AMP-binding.2"
                     /domains="nrpspksdomains_aptA_PCP.2"
                     /domains="nrpspksdomains_aptA_Epimerization.1"
                     /domains="nrpspksdomains_aptA_TIGR01720.1"
                     /locus_tags="aptA"
                     /monomer_pairings="Lys -> D-Lys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2026..2139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0006"
                     /evalue="1.20E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="aptA"
                     /protein_end="713"
                     /protein_start="675"
                     /score="37.0"
                     /tool="antismash"
                     /translation="AYQFQATMRFRGWLDVTVLQKCLNEIVLRHEIFRTTYP"
     CDS_motif       2359..2421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0007"
                     /evalue="5.50E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="aptA"
                     /protein_end="807"
                     /protein_start="786"
                     /score="25.4"
                     /tool="antismash"
                     /translation="HHMAHDGWSFNVFLGELVELY"
     CDS_motif       2470..2505
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0008"
                     /evalue="3.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="aptA"
                     /protein_end="835"
                     /protein_start="823"
                     /score="16.2"
                     /tool="antismash"
                     /translation="QFADFAHWQREW"
     CDS_motif       2761..2850
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0009"
                     /evalue="4.50E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="aptA"
                     /protein_end="950"
                     /protein_start="920"
                     /score="28.8"
                     /tool="antismash"
                     /translation="DINVGTAVANRRMHEIEKLIGMIVNNLVLR"
     CDS_motif       2899..3018
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0010"
                     /evalue="2.20E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aptA"
                     /protein_end="1006"
                     /protein_start="966"
                     /score="65.0"
                     /tool="antismash"
                     /translation="RSCTMEAYANEDLPFDKVVEVLKPIRNLSHNPLFQVMFSF"
     aSDomain        3391..4611
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_AMP-binding.2"
                     /evalue="3.50E-116"
                     /label="aptA_AMP-binding.2"
                     /locus_tag="aptA"
                     /protein_end="1537"
                     /protein_start="1130"
                     /score="380.0"
                     /specificity="substrate consensus: Lys"
                     /tool="antismash"
                     /translation="FAAQVELTPNAIAVEQDGQRLTYRELSDRTNQLAHYLQSLAVKPE
                     TLVGICVDRSLEMIVGLLGILKAGGAYVPLDPAYPKQRLADILADTQLGILLTQERFRS
                     QLPDYTGKTICLDTDWKVIAQNSTANPISDVQLHNLAYIIYTSGSTGKPKGVMIEHRSL
                     FNFVMTAIHEYEINATDRILQFASICFDTSIEEIFPCLCVGATLVLRTEQMLHSSDEFW
                     RCCQKWELTILDLPTAYWHQLVTELNPQDGRIPASLKTVIIGGEEVQLEKVKHWHSCVA
                     HIPHLPQLFNSYGPTEATVITTLHYLNSSAVTSVSIGRPISNAQVYVLDQYLQPVPVGV
                     PGELHIGGVSLARGYWQRPELTAEKFIQNPIPYATCDRLYKTGDLGRFRADGTLEYLGR
                     VDDQVKIR"
     CDS_motif       3577..3618
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0011"
                     /evalue="7.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="aptA"
                     /protein_end="1206"
                     /protein_start="1192"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       3811..3870
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0012"
                     /evalue="2.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="aptA"
                     /protein_end="1290"
                     /protein_start="1270"
                     /score="35.4"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIEH"
     CDS_motif       4264..4296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0013"
                     /evalue="2.50E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="aptA"
                     /protein_end="1432"
                     /protein_start="1421"
                     /score="7.6"
                     /tool="antismash"
                     /translation="SYGPTEATVIT"
     CDS_motif       4399..4488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0014"
                     /evalue="1.10E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="aptA"
                     /protein_end="1496"
                     /protein_start="1466"
                     /score="56.0"
                     /tool="antismash"
                     /translation="PVGVPGELHIGGVSLARGYWQRPELTAEKF"
     CDS_motif       4576..4641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0015"
                     /evalue="9.30E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="aptA"
                     /protein_end="1547"
                     /protein_start="1525"
                     /score="40.0"
                     /tool="antismash"
                     /translation="YLGRVDDQVKIRGFRIELGEIE"
     aSDomain        4936..5130
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_PCP.2"
                     /evalue="2.50E-25"
                     /label="aptA_PCP.2"
                     /locus_tag="aptA"
                     /protein_end="1710"
                     /protein_start="1645"
                     /score="80.3"
                     /tool="antismash"
                     /translation="EEKLTAIWSEILRLEKVGIHDNFFELGGDSILSIQIISRANQAGI
                     QIAPKQLFKYQTIAELAAVA"
     aSDomain        5170..6090
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_Epimerization.1"
                     /evalue="5.30E-157"
                     /label="aptA_Epimerization.1"
                     /locus_tag="aptA"
                     /protein_end="2030"
                     /protein_start="1723"
                     /score="515.7"
                     /tool="antismash"
                     /translation="TGQVMLTPIQQWFFEQKLSEPHYFNQSALLEVLPDFKSEQLQQVV
                     QQLLQHHDALRLRFVQEGENWQQINAATQESLPLSVIDLSHLSPEEQQTAMKAADAELQ
                     ASLDLSTGAIARIALFQLGKNQPGRLLLIIHHLAVDGISWRILLEDLATAYEQISRGDA
                     IKLPPKTTSFQYWSDRLTEYGRSEAIATELDYWLSEYNFKVTALPVDYPSNKEDNTVAS
                     TACMSLSLTEEQTRALLQDVPSAYNTQINDVLLTALVQSFSQWTGERSLLIDLEGHGRE
                     DLFEDVDLSRTVGWFTTLFPVRLQLE"
     CDS_motif       5185..5214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0016"
                     /evalue="2.70E-04"
                     /label="NRPS-E1"
                     /locus_tag="aptA"
                     /protein_end="1738"
                     /protein_start="1728"
                     /score="13.8"
                     /tool="antismash"
                     /translation="LTPIQQWFFE"
     CDS_motif       5287..5349
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0017"
                     /evalue="3.60E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="aptA"
                     /protein_end="1783"
                     /protein_start="1762"
                     /score="16.4"
                     /tool="antismash"
                     /translation="QLQQVVQQLLQHHDALRLRFV"
     CDS_motif       5557..5622
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0018"
                     /evalue="9.90E-11"
                     /label="NRPS-E2"
                     /locus_tag="aptA"
                     /protein_end="1874"
                     /protein_start="1852"
                     /score="33.8"
                     /tool="antismash"
                     /translation="LLLIIHHLAVDGISWRILLEDL"
     CDS_motif       6031..6081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0019"
                     /evalue="4.90E-09"
                     /label="NRPS-E5"
                     /locus_tag="aptA"
                     /protein_end="2027"
                     /protein_start="2010"
                     /score="28.1"
                     /tool="antismash"
                     /translation="DLSRTVGWFTTLFPVRL"
     aSDomain        6106..6564
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_TIGR01720.1"
                     /evalue="7.20E-47"
                     /label="aptA_TIGR01720.1"
                     /locus_tag="aptA"
                     /protein_end="2188"
                     /protein_start="2035"
                     /score="150.9"
                     /tool="antismash"
                     /translation="GEALKLVKEQLRGIPNRGIGYGVLRYLNENAAIRTKLQALPQAQV
                     SFNYLGQFDQVLKASDVLGLAKEFKAEQSLLNKRSHLLGISGLIRAEKLEMTWSYSEKV
                     HQRTTIERLALGFMEALKTLIAHCQSPDAISHTPSDFSAAKLSQKQLDK"
     CDS_motif       6124..6186
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptA_0020"
                     /evalue="4.00E-11"
                     /label="NRPS-E6"
                     /locus_tag="aptA"
                     /protein_end="2062"
                     /protein_start="2041"
                     /score="35.0"
                     /tool="antismash"
                     /translation="VKEQLRGIPNRGIGYGVLRYL"
     aSDomain        6517..6579
                     /aSDomain="NRPS-COM_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptA_NRPS-COM_Cterm.1"
                     /evalue="3.00E-09"
                     /label="aptA_NRPS-COM_Cterm.1"
                     /locus_tag="aptA"
                     /protein_end="2193"
                     /protein_start="2172"
                     /score="28.4"
                     /tool="antismash"
                     /translation="PSDFSAAKLSQKQLDKFLAKI"
     gene            6611..9820
                     /gene="aptB"
     CDS             6611..9820
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (1-27). E-value: 1.2e-17.
                     Score: 54.7. Matches aSDomain:
                     nrpspksdomains_aptB_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (4-299). E-value:
                     2.5e-119. Score: 389.7. Matches aSDomain:
                     nrpspksdomains_aptB_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (462-860). E-value:
                     8.5e-111. Score: 362.3. Matches aSDomain:
                     nrpspksdomains_aptB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (969-1035). E-value: 4.8e-27. Score:
                     85.9. Matches aSDomain: nrpspksdomains_aptB_PCP.1"
                     /codon_start=1
                     /gene="aptB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     368.8; E-value: 7.7e-112)"
                     /gene_kind="biosynthetic"
                     /note="nonribosomal peptide synthetase"
                     /product="AptB"
                     /protein_id="QNL14921.1"
                     /sec_met_domain="Condensation (E-value: 9.4e-76, bitscore:
                     243.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-119, bitscore:
                     387.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.8e-17, bitscore:
                     51.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNIEDLYELSPMQQGMLFHTLYAPESEIYFEQLLCILCGELNFP
                     TFQQAWQQVVARHPVLRSSFYWEEIEKPLQMVSKQMELPWVELDWRHLTPNEQQQNLED
                     FLEGDRQKEFDLSQAPLMRFTIIQLGEKTYQFIWSHHHILFDGWSMQIVLKEVLALYEA
                     NQRGEHLRLLPARPYREYIDWLQQQNITQAKNFWQQTLQGFEVPTLLGGNRGQGKYNEQ
                     RFQLSQTVTEKLQSATRQHHLTLNNLVQGAWALLISRYSGESDVVFGATVSGRPPNLAG
                     VDSMVGLLINTLPIRVQVTSKTELLPWLKHLQSQAFEQEQYTYYSLAEIQRLSNVPPGI
                     PLFESLLVFENYPLDSAEQESKKSLEISHLRCFERTNYPLTVVVNPESKLSGRIIYDTS
                     RFEEQTIERMIGHFQTLLQGMAANLQQYISQLSLLSAAEEEQLILQENQQKTASIHYKC
                     IHTLFEEQVEKTPDAVAVVYEKEYLTYRDLNNRANQLAHYLQALGVKPEVRVEICVERS
                     PLMVVGILAILKAGGAYVPVDSAYPSERLEFMLKDVQAPILLTQTHLCEQLPIDNQTVV
                     NLDSDWKIIDQYKEDNLPSEVNPENLAYIIYTSGSTGTPKGTEVPHRSIIGFMFGVDYI
                     QLDANQIWLQHSSISWDGLTLELWPPLLHGGRCVLYPDQIPTPEGLSRIITEQQVNTLF
                     LTTALFNLMIDTMPEGLLGIKQLLTGGESVSVAHVRHALELLPETQIINAYGPCECTVI
                     TSCYPISKQLGQNVHSIPIGKPIGDRTVYLLDRDLHRVPIGVPGELYVGGASVARGYLN
                     QPTLTREKFIPNPFLEGDTLYKTGDLVRRLPDGNLEFLGRIDTQVKIRGFRIELEEIEA
                     VLNQNPDIKQVVAIIREDEPGNKYLVAYLLTTDNPPTASTLRNFLNQKLPDYMIPSAFV
                     FLEEFPLTPNGKINRRALPAPDASQRNLEVDFVAPRTPTEQELAMIWTEVLKLKQIGIY
                     DNFFELGGHSLLATQVVSRLREVFSLDFPLRYVFENPTIAELAQKVIDQQIEQAENDEL
                     TQLLGEVEQLSEEEVTQQLLF"
     aSDomain        6614..6691
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptB_NRPS-COM_Nterm.1"
                     /evalue="1.20E-17"
                     /label="aptB_NRPS-COM_Nterm.1"
                     /locus_tag="aptB"
                     /protein_end="27"
                     /protein_start="1"
                     /score="54.7"
                     /tool="antismash"
                     /translation="DNIEDLYELSPMQQGMLFHTLYAPES"
     aSDomain        6623..7507
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptB_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.50E-119"
                     /label="aptB_Condensation_DCL.1"
                     /locus_tag="aptB"
                     /protein_end="299"
                     /protein_start="4"
                     /score="389.7"
                     /tool="antismash"
                     /translation="EDLYELSPMQQGMLFHTLYAPESEIYFEQLLCILCGELNFPTFQQ
                     AWQQVVARHPVLRSSFYWEEIEKPLQMVSKQMELPWVELDWRHLTPNEQQQNLEDFLEG
                     DRQKEFDLSQAPLMRFTIIQLGEKTYQFIWSHHHILFDGWSMQIVLKEVLALYEANQRG
                     EHLRLLPARPYREYIDWLQQQNITQAKNFWQQTLQGFEVPTLLGGNRGQGKYNEQRFQL
                     SQTVTEKLQSATRQHHLTLNNLVQGAWALLISRYSGESDVVFGATVSGRPPNLAGVDSM
                     VGLLINTLPIRVQV"
     aSModule        6623..9715
                     /complete
                     /domains="nrpspksdomains_aptB_Condensation_DCL.1"
                     /domains="nrpspksdomains_aptB_AMP-binding.1"
                     /domains="nrpspksdomains_aptB_PCP.1"
                     /locus_tags="aptB"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6632..6673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0001"
                     /evalue="1.50E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="aptB"
                     /protein_end="21"
                     /protein_start="7"
                     /score="16.7"
                     /tool="antismash"
                     /translation="YELSPMQQGMLFHT"
     CDS_motif       6698..6811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0002"
                     /evalue="1.10E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="aptB"
                     /protein_end="67"
                     /protein_start="29"
                     /score="53.1"
                     /tool="antismash"
                     /translation="YFEQLLCILCGELNFPTFQQAWQQVVARHPVLRSSFYW"
     CDS_motif       7028..7093
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0003"
                     /evalue="9.80E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="aptB"
                     /protein_end="161"
                     /protein_start="139"
                     /score="37.2"
                     /tool="antismash"
                     /translation="HHHILFDGWSMQIVLKEVLALY"
     CDS_motif       7139..7177
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0004"
                     /evalue="1.50E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="aptB"
                     /protein_end="189"
                     /protein_start="176"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PYREYIDWLQQQN"
     CDS_motif       7403..7498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0005"
                     /evalue="2.30E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="aptB"
                     /protein_end="296"
                     /protein_start="264"
                     /score="61.8"
                     /tool="antismash"
                     /translation="DVVFGATVSGRPPNLAGVDSMVGLLINTLPIR"
     CDS_motif       7547..7669
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0006"
                     /evalue="5.90E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="aptB"
                     /protein_end="353"
                     /protein_start="312"
                     /score="63.7"
                     /tool="antismash"
                     /translation="QSQAFEQEQYTYYSLAEIQRLSNVPPGIPLFESLLVFENYP"
     aSDomain        7997..9190
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptB_AMP-binding.1"
                     /evalue="8.50E-111"
                     /label="aptB_AMP-binding.1"
                     /locus_tag="aptB"
                     /protein_end="860"
                     /protein_start="462"
                     /score="362.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQVEKTPDAVAVVYEKEYLTYRDLNNRANQLAHYLQALGVKPE
                     VRVEICVERSPLMVVGILAILKAGGAYVPVDSAYPSERLEFMLKDVQAPILLTQTHLCE
                     QLPIDNQTVVNLDSDWKIIDQYKEDNLPSEVNPENLAYIIYTSGSTGTPKGTEVPHRSI
                     IGFMFGVDYIQLDANQIWLQHSSISWDGLTLELWPPLLHGGRCVLYPDQIPTPEGLSRI
                     ITEQQVNTLFLTTALFNLMIDTMPEGLLGIKQLLTGGESVSVAHVRHALELLPETQIIN
                     AYGPCECTVITSCYPISKQLGQNVHSIPIGKPIGDRTVYLLDRDLHRVPIGVPGELYVG
                     GASVARGYLNQPTLTREKFIPNPFLEGDTLYKTGDLVRRLPDGNLEFLGRIDTQVKIR"
     CDS_motif       8183..8224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0007"
                     /evalue="4.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="aptB"
                     /protein_end="538"
                     /protein_start="524"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LAILKAGGAYVPVD"
     CDS_motif       8417..8476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0008"
                     /evalue="3.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="aptB"
                     /protein_end="622"
                     /protein_start="602"
                     /score="28.6"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGTEVPH"
     CDS_motif       8984..9073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0009"
                     /evalue="4.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="aptB"
                     /protein_end="821"
                     /protein_start="791"
                     /score="54.2"
                     /tool="antismash"
                     /translation="PIGVPGELYVGGASVARGYLNQPTLTREKF"
     CDS_motif       9155..9220
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptB_0010"
                     /evalue="5.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="aptB"
                     /protein_end="870"
                     /protein_start="848"
                     /score="37.5"
                     /tool="antismash"
                     /translation="FLGRIDTQVKIRGFRIELEEIE"
     aSDomain        9518..9715
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptB_PCP.1"
                     /evalue="4.80E-27"
                     /label="aptB_PCP.1"
                     /locus_tag="aptB"
                     /protein_end="1035"
                     /protein_start="969"
                     /score="85.9"
                     /tool="antismash"
                     /translation="EQELAMIWTEVLKLKQIGIYDNFFELGGHSLLATQVVSRLREVFS
                     LDFPLRYVFENPTIAELAQKV"
     gene            9922..17688
                     /gene="aptC"
     CDS             9922..17688
                     /NRPS_PKS="Domain: Condensation_LCL (46-347). E-value:
                     1.7e-120. Score: 393.4. Matches aSDomain:
                     nrpspksdomains_aptC_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (511-905). E-value:
                     8.8e-118. Score: 385.3. Matches aSDomain:
                     nrpspksdomains_aptC_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1010-1079). E-value: 1.2e-25.
                     Score: 81.4. Matches aSDomain: nrpspksdomains_aptC_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1095-1397). E-value:
                     1.3e-111. Score: 364.2. Matches aSDomain:
                     nrpspksdomains_aptC_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1563-1972). E-value:
                     3.3e-100. Score: 327.4. Matches aSDomain:
                     nrpspksdomains_aptC_AMP-binding.2"
                     /NRPS_PKS="Domain: nMT (2061-2278). E-value: 9.2e-107.
                     Score: 348.7. Matches aSDomain: nrpspksdomains_aptC_nMT.1"
                     /NRPS_PKS="Domain: PCP (2490-2564). E-value: 1.1e-21.
                     Score: 68.7. Matches aSDomain: nrpspksdomains_aptC_PCP.2"
                     /codon_start=1
                     /gene="aptC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     406; E-value: 4e-123)"
                     /gene_kind="biosynthetic"
                     /note="nonribosomal peptide synthetase"
                     /product="AptC"
                     /protein_id="QNL14923.1"
                     /sec_met_domain="Condensation (E-value: 3.4e-86, bitscore:
                     277.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.9e-125, bitscore:
                     405.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-18, bitscore:
                     54.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDILKRLETLSPEKRELVLQKLKKQQQSSQNDHRLTPPLTPVSR
                     EQPLPLSFAQQRLWFLDQLEGENCVYNVPFFWQISGFLNISALEQAIAEIVQRHEVLRT
                     SFSVVDESPIQVIHANPQLTIQVLDWRQLTEKDQLKKAHQLATEELQQPFDLSNPPLLR
                     VKLLQLTDQSHLLLLVIHHIVCDGWSMDIFRRELFTLYTAFCAVKPSPLPALPLQYADF
                     AHWQRQWLQGEVLQTQLNYWQKQLAEVPPLLELPTDKPRPSVQSFRGRSEFLKLNQDLT
                     QKLKRLSQESGTTLFMTLLAAFTLLLSRYSRQEDIVVGSAIANRNRREIEPLIGFFVNT
                     LALRTNLQGNPTFLELLNRVKQVTLDAYDHQDLPFEKLVDELGIERSLSHHPLFQVAFS
                     LQNATQEKLEIPGLTLTRFEWENTTTLFDLSLIFRETLQGLIGEWEYATDLFEPTTIQR
                     MAGHFEVLLQAIVDNPRQPINTLPLMTAAEVLQLQCWNQTQIEYPEDKTLVDLFEQQVK
                     KNPHNIALVFESQSLTYQQLNQKANQLAHYLIQNHQIQPDTLISICVERSIEMIIGLLG
                     ILKAGGAYVPIDPNYPKQRIGFMLEDSGTSVLLTQSFLTEQLPLTELENSPKIICLDQE
                     TFAQELTDNPSPQSTPLDLAYAIYTSGSTGQPKGVMISHRGLVNMTLAVEQILLLQPQS
                     RVLQFASFSFDASISEIATALAAGTCLYLAKKETLLPSQSLVDFLAEHKITHSFLPPSA
                     LSVLPQATLPDLQTIGVGGEACPAELVTQWAQGRRFFNCYGPTESTVNAAIALVQPNGK
                     KPPIGKPLPNIRIYILDAYNQLLPPGIPGELCIAGVGLARGYLNRPETTAEKFLEVELF
                     GKIERIYKTGDLARWNSDGNLEYLSRIDDQVKLRGFRIELGEIESILLQHPSVKEAVAI
                     LSEADNNPRLVAYVTTEKSVNLGGQFKDYLKTRLPNYMVPSQILVLDKFPLSPNGKLDR
                     KALPAPDPATSNDFEMPVTSTEELLATLWQGLLKVKSVGRPDNFFELGGHSLLATQLVV
                     RIRDSFGVELPVRKVFEQSVLSELATVIDKAASGFTLPPITAQPENEPKTLSFAQSRLW
                     FLAQLEGKGTSATYNMSAALQLDGNLCMEALRASFEYLLERHAILRTYFPALDGQPQVV
                     VKNLEDIEVLEIVDLREAPQQRTEIVQRLVDTHAQEPFDLNTGPLFKAKLLQLSQQKNV
                     LLLNMHHIISDGWSMGVFKREWEQAYAAFAAVDTPNLSPLPIQYSDYAAWQRSWLQGEI
                     LESQENYWKQQLGDAPRLLDLPTDHPRPAQQSYQGGREEYRLSSELTSLLKTVSQKHGV
                     SLFMTLLTAFSILLSRYSRQEDLCVGIAIANRTHSYTEGLIGFFVNTLVLRSQVKPEQG
                     FSELLQQTRQTCLDAYAHQDIPFEYLVEQLQPERSLSHNPLFQVMMVLQNAVGAGANVS
                     LPGLDIQYLEQSFPFAKFDLTLDLCERGDQLHCMWEYATDLFEAETIRRMAGHFEVLLT
                     AITQNPQQPISKLPLITTAEIQQLLTWNQTDTDYPQDQTLVTLFEQQVAKTPDNIAVVF
                     VDERSEASRRVEHSLSYQELNQKANQLADYLLQLKKEQQLPDNPLIAICMERSISMIVG
                     ILGILKAGGAYVPIDPSYPQERIHLMLEDSNASVLLTTNPIKKPLSLEKLQKTCHVVFL
                     EQETWVNQPTDNPNLQSRSDDLAYVIYTSGSTGRPKGVAIAHSSPVVLVKWAHSVFSAE
                     QLRGVLASTSMCFDLSIFEIFVPLTQGGSVIVVENALYIEQASNSIVPITLINTVPSAA
                     AELLKMNAIPSSVEVINLAGEPLKNTLVQALYQTTSVREVYNLYGPSEDTTYSTFTKVA
                     KNAQHEPTIGKAIANTRIYILDSYNQLLPPGIPGELCIAGAGLAQGYLNRPDLSAEKFI
                     NLKLFNQTERIYKTGDLARWLPDSNLEYLGRIDHQVKVRGFRIELSEIEASLVKHPKIQ
                     EAVVIVREETDLDKRLVAYIVPTATDQHTSQGEVVELWEQIFNDSYSQQQAPTDDPTLN
                     LAGWNDSYTAQPIPQTAMQEWRDTTVDQILELEPKQVWEIGCGTGMLLFQIAPHCQHYL
                     GTDFSPDALHYIEQHLKQQSLNDRVTLKASAANQFDGIETNAYDLVIMNSVIQYFPSLD
                     YFLEVLHGAVNAVTTQGAIFIGDVRNLNLLEAFHTAVEFYRAADELSIKDLRQQIQKSI
                     RNEGELLIDPDFFIALKQRIPRISHVQIQLKRGFAQTEMSRFRYDVVLHLDRADTSVAQ
                     SQWLDWQDQQLNLETIEKILTTQQPDLLGIKHIPNARLTSEMVLLEQIAQLEGTVSDLK
                     AAVAQAKLGIEPEAFRALGQDLPYTPFIQYSSTGFSNYDVVFQRNVPGQVTLPRFPTTD
                     NLRLKPWQHYANQPLQYRTNQVDPVLLEEWRDFLGKTLPEYMIPNHFTVLEKLPLTPNG
                     KVDRKALPAPDIAVPATDIELPVTETEKLLAQLWAKLLKYEAMPAAGYAYARQDNFFNL
                     GGHSLLATQLIARIRDTFKVELPLRKVFEYPTLSELANYLDTCIWVNSTDESMQPLNPD
                     EEEIEL"
     aSDomain        10060..10962
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.70E-120"
                     /label="aptC_Condensation_LCL.1"
                     /locus_tag="aptC"
                     /protein_end="347"
                     /protein_start="46"
                     /score="393.4"
                     /tool="antismash"
                     /translation="QPLPLSFAQQRLWFLDQLEGENCVYNVPFFWQISGFLNISALEQA
                     IAEIVQRHEVLRTSFSVVDESPIQVIHANPQLTIQVLDWRQLTEKDQLKKAHQLATEEL
                     QQPFDLSNPPLLRVKLLQLTDQSHLLLLVIHHIVCDGWSMDIFRRELFTLYTAFCAVKP
                     SPLPALPLQYADFAHWQRQWLQGEVLQTQLNYWQKQLAEVPPLLELPTDKPRPSVQSFR
                     GRSEFLKLNQDLTQKLKRLSQESGTTLFMTLLAAFTLLLSRYSRQEDIVVGSAIANRNR
                     REIEPLIGFFVNTLALRTNL"
     aSModule        10060..13158
                     /complete
                     /domains="nrpspksdomains_aptC_Condensation_LCL.1"
                     /domains="nrpspksdomains_aptC_AMP-binding.1"
                     /domains="nrpspksdomains_aptC_PCP.1"
                     /locus_tags="aptC"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10075..10107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0001"
                     /evalue="5.10E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="aptC"
                     /protein_end="62"
                     /protein_start="51"
                     /score="9.5"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     CDS_motif       10129..10239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0002"
                     /evalue="2.00E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="aptC"
                     /protein_end="106"
                     /protein_start="69"
                     /score="49.1"
                     /tool="antismash"
                     /translation="VYNVPFFWQISGFLNISALEQAIAEIVQRHEVLRTSF"
     CDS_motif       10459..10524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0003"
                     /evalue="3.20E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="aptC"
                     /protein_end="201"
                     /protein_start="179"
                     /score="38.8"
                     /tool="antismash"
                     /translation="IHHIVCDGWSMDIFRRELFTLY"
     CDS_motif       10573..10611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0004"
                     /evalue="1.00E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="aptC"
                     /protein_end="230"
                     /protein_start="217"
                     /score="18.0"
                     /tool="antismash"
                     /translation="QYADFAHWQRQWL"
     CDS_motif       10801..10854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0005"
                     /evalue="2.60E-01"
                     /label="Cy4"
                     /locus_tag="aptC"
                     /protein_end="311"
                     /protein_start="293"
                     /score="4.6"
                     /tool="antismash"
                     /translation="TLFMTLLAAFTLLLSRYS"
     CDS_motif       10864..10953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0006"
                     /evalue="3.10E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="aptC"
                     /protein_end="344"
                     /protein_start="314"
                     /score="51.6"
                     /tool="antismash"
                     /translation="DIVVGSAIANRNRREIEPLIGFFVNTLALR"
     CDS_motif       11002..11121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0007"
                     /evalue="3.10E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aptC"
                     /protein_end="400"
                     /protein_start="360"
                     /score="77.5"
                     /tool="antismash"
                     /translation="KQVTLDAYDHQDLPFEKLVDELGIERSLSHHPLFQVAFSL"
     aSDomain        11455..12636
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_AMP-binding.1"
                     /evalue="8.80E-118"
                     /label="aptC_AMP-binding.1"
                     /locus_tag="aptC"
                     /protein_end="905"
                     /protein_start="511"
                     /score="385.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQVKKNPHNIALVFESQSLTYQQLNQKANQLAHYLIQNHQIQP
                     DTLISICVERSIEMIIGLLGILKAGGAYVPIDPNYPKQRIGFMLEDSGTSVLLTQSFLT
                     EQLPLTELENSPKIICLDQETFAQELTDNPSPQSTPLDLAYAIYTSGSTGQPKGVMISH
                     RGLVNMTLAVEQILLLQPQSRVLQFASFSFDASISEIATALAAGTCLYLAKKETLLPSQ
                     SLVDFLAEHKITHSFLPPSALSVLPQATLPDLQTIGVGGEACPAELVTQWAQGRRFFNC
                     YGPTESTVNAAIALVQPNGKKPPIGKPLPNIRIYILDAYNQLLPPGIPGELCIAGVGLA
                     RGYLNRPETTAEKFLEVELFGKIERIYKTGDLARWNSDGNLEYLSRIDDQVKLR"
     CDS_motif       11644..11685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0008"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="aptC"
                     /protein_end="588"
                     /protein_start="574"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       11884..11943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0009"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="aptC"
                     /protein_end="674"
                     /protein_start="654"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYAIYTSGSTGQPKGVMISH"
     CDS_motif       12427..12516
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0010"
                     /evalue="8.70E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="aptC"
                     /protein_end="865"
                     /protein_start="835"
                     /score="53.2"
                     /tool="antismash"
                     /translation="PPGIPGELCIAGVGLARGYLNRPETTAEKF"
     CDS_motif       12601..12666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0011"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="aptC"
                     /protein_end="915"
                     /protein_start="893"
                     /score="36.2"
                     /tool="antismash"
                     /translation="YLSRIDDQVKLRGFRIELGEIE"
     CDS_motif       12874..12900
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0012"
                     /evalue="2.20E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="aptC"
                     /protein_end="993"
                     /protein_start="984"
                     /score="4.8"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     aSDomain        12952..13158
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_PCP.1"
                     /evalue="1.20E-25"
                     /label="aptC_PCP.1"
                     /locus_tag="aptC"
                     /protein_end="1079"
                     /protein_start="1010"
                     /score="81.4"
                     /tool="antismash"
                     /translation="EELLATLWQGLLKVKSVGRPDNFFELGGHSLLATQLVVRIRDSFG
                     VELPVRKVFEQSVLSELATVIDKA"
     aSDomain        13207..14112
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.30E-111"
                     /label="aptC_Condensation_LCL.2"
                     /locus_tag="aptC"
                     /protein_end="1397"
                     /protein_start="1095"
                     /score="364.2"
                     /tool="antismash"
                     /translation="PKTLSFAQSRLWFLAQLEGKGTSATYNMSAALQLDGNLCMEALRA
                     SFEYLLERHAILRTYFPALDGQPQVVVKNLEDIEVLEIVDLREAPQQRTEIVQRLVDTH
                     AQEPFDLNTGPLFKAKLLQLSQQKNVLLLNMHHIISDGWSMGVFKREWEQAYAAFAAVD
                     TPNLSPLPIQYSDYAAWQRSWLQGEILESQENYWKQQLGDAPRLLDLPTDHPRPAQQSY
                     QGGREEYRLSSELTSLLKTVSQKHGVSLFMTLLTAFSILLSRYSRQEDLCVGIAIANRT
                     HSYTEGLIGFFVNTLVLRSQV"
     aSModule        13207..17613
                     /complete
                     /domains="nrpspksdomains_aptC_Condensation_LCL.2"
                     /domains="nrpspksdomains_aptC_AMP-binding.2"
                     /domains="nrpspksdomains_aptC_nMT.1"
                     /domains="nrpspksdomains_aptC_PCP.2"
                     /locus_tags="aptC"
                     /monomer_pairings="Ala -> NMe-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       13219..13248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0013"
                     /evalue="3.40E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="aptC"
                     /protein_end="1109"
                     /protein_start="1099"
                     /score="7.2"
                     /tool="antismash"
                     /translation="SFAQSRLWFL"
     CDS_motif       13276..13392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0014"
                     /evalue="5.40E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="aptC"
                     /protein_end="1157"
                     /protein_start="1118"
                     /score="47.7"
                     /tool="antismash"
                     /translation="ATYNMSAALQLDGNLCMEALRASFEYLLERHAILRTYFP"
     CDS_motif       13609..13674
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0015"
                     /evalue="1.30E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="aptC"
                     /protein_end="1251"
                     /protein_start="1229"
                     /score="33.6"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVFKREWEQAY"
     CDS_motif       13723..13761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0016"
                     /evalue="1.70E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="aptC"
                     /protein_end="1280"
                     /protein_start="1267"
                     /score="17.3"
                     /tool="antismash"
                     /translation="QYSDYAAWQRSWL"
     CDS_motif       13945..14004
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0017"
                     /evalue="3.30E-01"
                     /label="Cy4"
                     /locus_tag="aptC"
                     /protein_end="1361"
                     /protein_start="1341"
                     /score="4.3"
                     /tool="antismash"
                     /translation="GVSLFMTLLTAFSILLSRYS"
     CDS_motif       14014..14103
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0018"
                     /evalue="6.10E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="aptC"
                     /protein_end="1394"
                     /protein_start="1364"
                     /score="44.3"
                     /tool="antismash"
                     /translation="DLCVGIAIANRTHSYTEGLIGFFVNTLVLR"
     CDS_motif       14152..14271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0019"
                     /evalue="5.90E-27"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aptC"
                     /protein_end="1450"
                     /protein_start="1410"
                     /score="86.2"
                     /tool="antismash"
                     /translation="RQTCLDAYAHQDIPFEYLVEQLQPERSLSHNPLFQVMMVL"
     aSDomain        14611..15837
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_AMP-binding.2"
                     /evalue="3.30E-100"
                     /label="aptC_AMP-binding.2"
                     /locus_tag="aptC"
                     /protein_end="1972"
                     /protein_start="1563"
                     /score="327.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FEQQVAKTPDNIAVVFVDERSEASRRVEHSLSYQELNQKANQLAD
                     YLLQLKKEQQLPDNPLIAICMERSISMIVGILGILKAGGAYVPIDPSYPQERIHLMLED
                     SNASVLLTTNPIKKPLSLEKLQKTCHVVFLEQETWVNQPTDNPNLQSRSDDLAYVIYTS
                     GSTGRPKGVAIAHSSPVVLVKWAHSVFSAEQLRGVLASTSMCFDLSIFEIFVPLTQGGS
                     VIVVENALYIEQASNSIVPITLINTVPSAAAELLKMNAIPSSVEVINLAGEPLKNTLVQ
                     ALYQTTSVREVYNLYGPSEDTTYSTFTKVAKNAQHEPTIGKAIANTRIYILDSYNQLLP
                     PGIPGELCIAGAGLAQGYLNRPDLSAEKFINLKLFNQTERIYKTGDLARWLPDSNLEYL
                     GRIDHQVKVR"
     CDS_motif       14839..14880
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0020"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="aptC"
                     /protein_end="1653"
                     /protein_start="1639"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       15079..15138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0021"
                     /evalue="6.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="aptC"
                     /protein_end="1739"
                     /protein_start="1719"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAIAH"
     CDS_motif       15628..15717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0022"
                     /evalue="2.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="aptC"
                     /protein_end="1932"
                     /protein_start="1902"
                     /score="51.9"
                     /tool="antismash"
                     /translation="PPGIPGELCIAGAGLAQGYLNRPDLSAEKF"
     CDS_motif       15802..15867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0023"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="aptC"
                     /protein_end="1982"
                     /protein_start="1960"
                     /score="36.2"
                     /tool="antismash"
                     /translation="YLGRIDHQVKVRGFRIELSEIE"
     aSDomain        16105..16755
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="9.20E-107"
                     /label="aptC_nMT.1"
                     /locus_tag="aptC"
                     /protein_end="2278"
                     /protein_start="2061"
                     /score="348.7"
                     /tool="antismash"
                     /translation="QPIPQTAMQEWRDTTVDQILELEPKQVWEIGCGTGMLLFQIAPHC
                     QHYLGTDFSPDALHYIEQHLKQQSLNDRVTLKASAANQFDGIETNAYDLVIMNSVIQYF
                     PSLDYFLEVLHGAVNAVTTQGAIFIGDVRNLNLLEAFHTAVEFYRAADELSIKDLRQQI
                     QKSIRNEGELLIDPDFFIALKQRIPRISHVQIQLKRGFAQTEMSRFRYDVVLHL"
     CDS_motif       17311..17337
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptC_0024"
                     /evalue="1.60E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="aptC"
                     /protein_end="2472"
                     /protein_start="2463"
                     /score="5.1"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        17392..17613
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptC_PCP.2"
                     /evalue="1.10E-21"
                     /label="aptC_PCP.2"
                     /locus_tag="aptC"
                     /protein_end="2564"
                     /protein_start="2490"
                     /score="68.7"
                     /tool="antismash"
                     /translation="EKLLAQLWAKLLKYEAMPAAGYAYARQDNFFNLGGHSLLATQLIA
                     RIRDTFKVELPLRKVFEYPTLSELANYLD"
     gene            17750..18367
                     /gene="orf1"
     CDS             17750..18367
                     /codon_start=1
                     /gene="orf1"
                     /product="ORF1"
                     /protein_id="QNL14924.1"
                     /transl_table=11
                     /translation="MIALSDSIFLTPEAYLQLEEKNNIKHEYIDGQVYAMAGTTDTHNT
                     IGLNLALFIRNHFRGSDCRVYFADVKVNLERRNRFYYPDIIVTCDPKDRETSTYKIFPK
                     LIIEVLSESTEAFDRGDKFNDYQTLDSLEEYVLVNSKRQRFETFRCNDQGLWVLQTYTP
                     DDQTFELQSINLTASFTDLYQDVELEAMSTTGYANAPKPDLS"
     gene            18460..22653
                     /gene="aptD"
     CDS             18460..22653
                     /NRPS_PKS="Domain: Condensation_LCL (83-381). E-value:
                     5.1e-116. Score: 378.7. Matches aSDomain:
                     nrpspksdomains_aptD_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (545-939). E-value:
                     7.6e-120. Score: 392.1. Matches aSDomain:
                     nrpspksdomains_aptD_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1043-1112). E-value: 3.9e-26.
                     Score: 83.0. Matches aSDomain: nrpspksdomains_aptD_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1131-1389). E-value:
                     2e-30. Score: 98.8. Matches aSDomain:
                     nrpspksdomains_aptD_Thioesterase.1"
                     /codon_start=1
                     /gene="aptD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     429.3; E-value: 3.4e-130)"
                     /gene_kind="biosynthetic"
                     /note="nonribosomal peptide synthetase"
                     /product="AptD"
                     /protein_id="QNL14925.1"
                     /sec_met_domain="Condensation (E-value: 7.4e-82, bitscore:
                     263.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.2e-127, bitscore:
                     412.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     52.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKNMTKNKQVVSLMLRLQNMGCRIWAEDDKLRIRTSKNALTSEL
                     KQEIQNNKAEILAFLNAAKAKTIMAEEIPTLSADAPKFLSFAQQRLWLLAQLTGPSATY
                     NMPMALQLEGNLNIDALRSSLAYLLNRHTSLRMYFPTVAGQPQVLIQDLDKIEVLAVLD
                     WQNLNEHPNSPTVQRLIDAHTQEPFDLNTGPLFKAKLLQLQEQKYVLLINMHHIISDGW
                     SMGVFVRELRQAYTAFTQSQTPNLAPLPIQYSDYANWQRNWLQGEVLENQIDYWKHQLQ
                     DASPLLELPTDYPRPAQQSYRGDRYLYSLTPELSAAVNTFSQQQGASLFMILLAALSLL
                     LSRYSRQNDLCIGSPIANRTHSQTESLIGFFVNTLVLRTQIKPEQSFIEFLQQTRSSCL
                     DAYAHQDIPFELLVEKLQPERSMSHNPLFQVMLALENNESPDLSLPGLEIQWLGVKGAI
                     AKFDLTLLVMEYDNQLNCSWDYATDLFEKSTIQRMAEQFEVLLKEILDNPHQPINTLPL
                     MTATELLQLQRWNQTQTDYPQDKTLVDLFEAQVEKNSQNLALVFESQQLTYQQLNQKAN
                     QLAHYLIHNYQIHPDTLISICVERSLEMIIGILGILKAGGAYVPIDPNYPTERIQFMLE
                     DSGTSVLLTQSYLTDQLPLTELEHPPQVICLDEETFAEELTDNPSPKSTPDDLAYVIYT
                     SGSTGRPKGVMISHQGLVNMTLAVDQVLQIQPQSRLLQFASFSFDASIWEIATALAAGA
                     CLYLAKKETLLPNQDLVNFLGDRKISHVTLPPSVLSLLPQATLPNLQTVVTAGEACPTE
                     LVTRWAKGRRFFNAYGPTESTVCATIALVQPNGKKPPIGQPLPNIRIYILDANNQLLPP
                     GIPGELCIAGMGLARGYLNRPDLTADKFLEVELFGKTERIYKTGDLARWGDDGNLEYLG
                     RIDDQVKLRGFRIELAEIEASLLQHPLVKEAIVTLYKTENNQSLIAYVTGMTTDLPTQL
                     KNHLKSRLPDYMIPAQIIVLDKLPLTPNGKIDRKALPVPNFEVGSSYTAPRNQVEKQLA
                     QVWSAVLERQEIGIHDNFFDLGGHSLLAMKLLNNIQQVFDQQLGLSSLFQNPTIAQLAQ
                     QLGNTEVQQSHADLLSLQPQGDAVPLFCLPGANGHGFYFRDLAINLGNEQPVYGLETPG
                     RDGLNALPDSVAAHATQLISLLRQQQAKSPYILAGYSSGCAVAFEMAAQLEQQGEKVGL
                     LAILDSALVSQPEYLTDRADIDWIWQLLQRIEALKGVSSGLKYADLAAQPDDQARWDLA
                     AEYVYRYNVLPEHASLSLLKTNMQVMKVLTLNYANYQPNHRISAPIVLFRAQEVHEILL
                     QELQAISDYDLPDWGWQAYTQKPVKVISVPGNHGRMLSEPNVKILARELLNTIK"
     aSDomain        18709..19602
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptD_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.10E-116"
                     /label="aptD_Condensation_LCL.1"
                     /locus_tag="aptD"
                     /protein_end="381"
                     /protein_start="83"
                     /score="378.7"
                     /tool="antismash"
                     /translation="LSFAQQRLWLLAQLTGPSATYNMPMALQLEGNLNIDALRSSLAYL
                     LNRHTSLRMYFPTVAGQPQVLIQDLDKIEVLAVLDWQNLNEHPNSPTVQRLIDAHTQEP
                     FDLNTGPLFKAKLLQLQEQKYVLLINMHHIISDGWSMGVFVRELRQAYTAFTQSQTPNL
                     APLPIQYSDYANWQRNWLQGEVLENQIDYWKHQLQDASPLLELPTDYPRPAQQSYRGDR
                     YLYSLTPELSAAVNTFSQQQGASLFMILLAALSLLLSRYSRQNDLCIGSPIANRTHSQT
                     ESLIGFFVNTLVLRTQI"
     aSModule        18709..22626
                     /complete
                     /domains="nrpspksdomains_aptD_Condensation_LCL.1"
                     /domains="nrpspksdomains_aptD_AMP-binding.1"
                     /domains="nrpspksdomains_aptD_PCP.1"
                     /domains="nrpspksdomains_aptD_Thioesterase.1"
                     /final_module
                     /locus_tags="aptD"
                     /monomer_pairings="Phe -> Phe"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       18763..18879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0001"
                     /evalue="2.70E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="aptD"
                     /protein_end="140"
                     /protein_start="101"
                     /score="45.5"
                     /tool="antismash"
                     /translation="ATYNMPMALQLEGNLNIDALRSSLAYLLNRHTSLRMYFP"
     CDS_motif       19099..19164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0002"
                     /evalue="4.60E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="aptD"
                     /protein_end="235"
                     /protein_start="213"
                     /score="41.5"
                     /tool="antismash"
                     /translation="MHHIISDGWSMGVFVRELRQAY"
     CDS_motif       19213..19251
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0003"
                     /evalue="1.10E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="aptD"
                     /protein_end="264"
                     /protein_start="251"
                     /score="17.8"
                     /tool="antismash"
                     /translation="QYSDYANWQRNWL"
     CDS_motif       19504..19593
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0004"
                     /evalue="1.70E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="aptD"
                     /protein_end="378"
                     /protein_start="348"
                     /score="55.7"
                     /tool="antismash"
                     /translation="DLCIGSPIANRTHSQTESLIGFFVNTLVLR"
     CDS_motif       19642..19761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0005"
                     /evalue="2.60E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="aptD"
                     /protein_end="434"
                     /protein_start="394"
                     /score="81.0"
                     /tool="antismash"
                     /translation="RSSCLDAYAHQDIPFELLVEKLQPERSMSHNPLFQVMLAL"
     aSDomain        20095..21276
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptD_AMP-binding.1"
                     /evalue="7.60E-120"
                     /label="aptD_AMP-binding.1"
                     /locus_tag="aptD"
                     /protein_end="939"
                     /protein_start="545"
                     /score="392.1"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FEAQVEKNSQNLALVFESQQLTYQQLNQKANQLAHYLIHNYQIHP
                     DTLISICVERSLEMIIGILGILKAGGAYVPIDPNYPTERIQFMLEDSGTSVLLTQSYLT
                     DQLPLTELEHPPQVICLDEETFAEELTDNPSPKSTPDDLAYVIYTSGSTGRPKGVMISH
                     QGLVNMTLAVDQVLQIQPQSRLLQFASFSFDASIWEIATALAAGACLYLAKKETLLPNQ
                     DLVNFLGDRKISHVTLPPSVLSLLPQATLPNLQTVVTAGEACPTELVTRWAKGRRFFNA
                     YGPTESTVCATIALVQPNGKKPPIGQPLPNIRIYILDANNQLLPPGIPGELCIAGMGLA
                     RGYLNRPDLTADKFLEVELFGKTERIYKTGDLARWGDDGNLEYLGRIDDQVKLR"
     CDS_motif       20284..20325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0006"
                     /evalue="5.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="aptD"
                     /protein_end="622"
                     /protein_start="608"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       20524..20583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0007"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="aptD"
                     /protein_end="708"
                     /protein_start="688"
                     /score="35.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVMISH"
     CDS_motif       21067..21156
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0008"
                     /evalue="5.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="aptD"
                     /protein_end="899"
                     /protein_start="869"
                     /score="53.9"
                     /tool="antismash"
                     /translation="PPGIPGELCIAGMGLARGYLNRPDLTADKF"
     CDS_motif       21241..21306
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0009"
                     /evalue="2.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="aptD"
                     /protein_end="949"
                     /protein_start="927"
                     /score="38.5"
                     /tool="antismash"
                     /translation="YLGRIDDQVKLRGFRIELAEIE"
     aSDomain        21589..21795
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptD_PCP.1"
                     /evalue="3.90E-26"
                     /label="aptD_PCP.1"
                     /locus_tag="aptD"
                     /protein_end="1112"
                     /protein_start="1043"
                     /score="83.0"
                     /tool="antismash"
                     /translation="EKQLAQVWSAVLERQEIGIHDNFFDLGGHSLLAMKLLNNIQQVFD
                     QQLGLSSLFQNPTIAQLAQQLGNT"
     aSDomain        21853..22626
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_aptD_Thioesterase.1"
                     /evalue="2.00E-30"
                     /label="aptD_Thioesterase.1"
                     /locus_tag="aptD"
                     /protein_end="1389"
                     /protein_start="1131"
                     /score="98.8"
                     /tool="antismash"
                     /translation="PLFCLPGANGHGFYFRDLAINLGNEQPVYGLETPGRDGLNALPDS
                     VAAHATQLISLLRQQQAKSPYILAGYSSGCAVAFEMAAQLEQQGEKVGLLAILDSALVS
                     QPEYLTDRADIDWIWQLLQRIEALKGVSSGLKYADLAAQPDDQARWDLAAEYVYRYNVL
                     PEHASLSLLKTNMQVMKVLTLNYANYQPNHRISAPIVLFRAQEVHEILLQELQAISDYD
                     LPDWGWQAYTQKPVKVISVPGNHGRMLSEPNVKILA"
     CDS_motif       22033..22107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_aptD_0010"
                     /evalue="8.50E-11"
                     /label="NRPS-te1"
                     /locus_tag="aptD"
                     /protein_end="1216"
                     /protein_start="1191"
                     /score="34.2"
                     /tool="antismash"
                     /translation="QAKSPYILAGYSSGCAVAFEMAAQL"
     gene            22713..24923
                     /gene="aptE"
     CDS             22713..24923
                     /codon_start=1
                     /gene="aptE"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 115; E-value:
                     7.5e-35)"
                     /gene_kind="transport"
                     /note="ABC transporter"
                     /product="AptE"
                     /protein_id="QNL14926.1"
                     /transl_table=11
                     /translation="MQSTTFVKKTSTNDSSPGFNQFWENVRALTGSYWYPTEAGGRAFS
                     DVLRSWGMLILLILLIVMLVAVTVFNSFINRYLLDILVEEKEPTKLVQILWLYGGALAC
                     VTLLIGLSKFVRKKIALDWYQWLNNQILEKYLSHRAYYKINFQSDVNNPDQRIAQQIEP
                     LTSNALSFSATFLEKVLEMLTFLVIIWSLSKLIAIALIVYTIIGNVIAVYLAQELNKIK
                     QEELESQADYTYSITHVRNHAESIAFFGGENQESNIIQRRFYQIIKSTKRKIDWERSQD
                     IFNRGYQAIIQIFPFIVFGPLQIRGEIDFGVIAQASLACNLFATAIAEIIREFANSGRF
                     SSYVERLTEFSNALEEVTKQPENVNTIKTIEENRLAFENVTLQTPNYEQVIVEDLSLVV
                     EPGEGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLVRPSLEEVLFLPQRPYIILGTLREQ
                     LLYPNTNRQMSDAELEEVLRQVNLQNLLTRIESFDTEVPWENILSLGEQQRLAFARLLI
                     THPNFTILDEATSALDLTNEGYLYEQLQSTKTTFISVGHRESLFNYHQWVLELSQDSSW
                     RLLTVQDYRLQKANEIITNPPDNSQITEANEIITNPPDNSQITEVNEIITNPPENPSTT
                     LRVNPQITEANEIITNPPENPSTTLRVNPQITIDVSPQNQSLEPPETSTISGLSHKEMQ
                     ILTGVSINTIRSKGSLGKTITTKDGVTYRYDKDPNVLKWVRV"
ORIGIN
        1 atgcaagaaa atttggttag ctctactcat tatattaatg atttttatgc cttaactgag
       61 caggagcaat ataaaatatt ggtggaatgg aatgatacaa cggtagatta ccctaaagat
      121 ttttgtatac atcagttatt tgaagcacaa gttgaaaaaa ctccagacaa tattgctgtt
      181 gtcttcaatg aacagaaatt tacctatcaa gagttgaacc accgagccaa caaagtagca
      241 cattatctgc aatttttggg tgtgggaaca gaagttctgg tggggatttg tgttgatcgg
      301 tctttggaaa tgatagtggg aatgttggga attctcaagg cgggtggagc atatgtaccc
      361 ttagatccaa catatcctca agaacgttta tcgttcatgc tgtcagattc acaagtgcaa
      421 gtgctgttga ctcagcaaaa gttcgttgca gagtttactg aaagtggcgt gaagacggtt
      481 tgtttggata ctgactggga attcatcaat caccaaagcc aagagaatcc tacgagcgac
      541 gcgacggctg aaaacctggc ttatgtcatc tatacatctg gttctacagg aacaccaaag
      601 ggagtagctg taccgcatcg ggctgtcaat cggttagtat gcaatactaa ctatgtgcag
      661 ttagacaaga gcgatgccta cggcggtaaa ctacgcattg cccaagcctc aaatgcttcc
      721 tttgacgcag ccactttcga gatctggggt tctctcctac acggggctag gctggtaatc
      781 attcctcaga atgttgtgct ttcgccccac cattttgcag cgtgcatccg cgagcaagga
      841 attagtgtat tattcttgac aacagcctta tttaatcagt tagcgggcgt tgttcctcaa
      901 gcatttaaag acctgcgata cttgctaatt ggcggcgacg ctttagatcc caagtcagtc
      961 aaaacagttc tgaggaatgg accaccacag cgattgataa atggttatgg accgactgag
     1021 agtacaacat tctcttgctg gtacttggtg gaggaggttg cagaaggggc aacaaatttg
     1081 ccgattggtc gcccaatttc caatacacaa atatatatat taaactccaa acttcaacca
     1141 gttcccattg gtactacagg cgaattatat attggcggcg acggtttggc acgaggctac
     1201 cttaaccgcc cagatttaac cgaagaaaaa tttattccca atccctttgg caattcaaaa
     1261 ttatataaaa caggtgactt agcccgttat ttaccagacg gtaacattga gtttatcggt
     1321 cgagtcgata atcaagtgaa gattcgcggc ttccgcattg aactcttaga aattgaggcg
     1381 gttttgagtc aacacccgga tgtatctcag gcagtggtgg ttgcccgtga agaaatacct
     1441 ggtgacaagc ggcttgtcgc ttatattgtc cttaatcaaa agtcagaagc gatgcctgcg
     1501 gcgggctttg cctacgctac tactttaaaa agcttcctgg aagcaaagct gcccaattac
     1561 atggtgccag caacctttat gattttggac accttgcccc tcacccctaa tggtaaggta
     1621 gatcgtcgga accttccagc gcccgatcgc tcacgccccg atttggaagc aacctttgtg
     1681 gcacctcgta actcaattga ggagaagtta gagatcatct gggctgagtt actaagactt
     1741 gagcaaattg gagttaatga taactttttc catctgggtg gtcattccct aattgcaact
     1801 caaatgcttt ctcgcgtgcg cgaagttttc caagtcgagt tatcttttca ccagatattt
     1861 gaaaacccca ccataggaag tttagctcaa ctcattgcac agggtcacaa agagcaacag
     1921 tggcaacatc ctgccataga acgaattcct catgagggac tcttgccagt ttcctttgcc
     1981 caagagcgag tgtactttat ccagcaattg gcttgtgaaa gtaacgccta ccaattccag
     2041 gcaacgatgc gatttcgagg ttggcttgat gtcacagtat tacaaaagtg cctcaacgag
     2101 attgtactgc gtcatgaaat ctttcgcacg acttatccgg cggtaaatgg aaagctattt
     2161 caggtaatta acccacacca accaatcagt ttcacagtga ttgacctcca gtcattccct
     2221 gaatatgagc gtgaagctga ggctcaaaag ctaattgaga tagaagtgca aaagcccttt
     2281 gacatgaatc aactaccatt agttaggtgg gttttgttga agttgagcga ccaagaacat
     2341 ttgttgatcc acattgagca tcacatggct catgatggtt ggtcattcaa cgtgttcctg
     2401 ggtgagttgg tagaacttta tcaagcattc tgtttggatc atccttcccc gcttcccgaa
     2461 ccactcttgc agttcgcgga ctttgctcat tggcagcgcg aatgggttaa caccgcagaa
     2521 gcccaagccc aattagctta ctggcaacaa aagttatcag gtagttctcc tctattagaa
     2581 ttacccacag atcgcccccg accaatagag caaacttacc aaggcgatca aatcaggatg
     2641 gaacttccca tcgacttgtg tgaatctctt agagttctta gtcgtcgaga gggtgtcacc
     2701 ttattcatga cgatgctggc agtttttcta gtcatgttgc accgatacac tgggcaagac
     2761 gacattaacg tggggacagc tgttgccaat cggcggatgc acgagataga gaagttaatt
     2821 ggcatgattg tcaataactt ggttttacgc accgatttgt caggtaatcc cacatttcgg
     2881 gagttacttg gtcgagtgcg ctcctgtact atggaagctt atgctaacga agacttacct
     2941 ttcgataaag tggtggaagt tctcaagcca atacgcaact tgagccacaa tccgctgttt
     3001 caagtgatgt tcagcttcca tgattcccca atgccggact tgagtctccc aggcttggac
     3061 atcagcttgc atgaacccat cagcaacaaa tccgccaagt ttgatttgga ttttctggtt
     3121 ataccgcgtc ttgaacaacg ggtgcagaat ggttctaaaa caggagccaa aggaatcacc
     3181 ttagtcttag aatacaatag cgacctcttc gatgctgcta caatccaacg aatgctagag
     3241 cagtatcaaa atttactata taaaattgta gccaacccag aacagcatat tggggaatta
     3301 cctctgttaa cccaaggtca acaacagtta ctggtgacat ggaattcaac tcacagagaa
     3361 tatccggaga gggagtgtat ctatcagtta tttgcggctc aggtggagtt aacgcctaat
     3421 gctatagctg tagaacagga tggtcaacgt ttaacctacc gtgaattgag cgatcgcacc
     3481 aatcaactag cacactattt gcaaagtttg gcagtcaaac cagaaaccct agttggtatc
     3541 tgcgttgacc gttccctaga aatgattgtt ggcttactcg gcattctcaa agcaggtggt
     3601 gcctatgtac ccctagatcc cgcctatcca aaacagcgac tggctgacat tcttgcagat
     3661 acgcaactag gcattttgct gactcaagaa agattccggt ctcaattacc agactatacc
     3721 ggaaaaacaa tttgtttaga tacggactgg aaagtaattg ctcaaaacag tacagccaac
     3781 ccgattagtg acgttcaact ccacaacctt gcctacatta tttacacctc tggttccacg
     3841 ggtaaaccca agggggtaat gatcgaacat cggtcactgt tcaattttgt catgactgct
     3901 atccacgaat atgaaattaa tgcaactgac cgcattctcc aatttgcttc tatttgcttt
     3961 gacacatcta ttgaagaaat ctttccttgt ttgtgtgttg gtgcaacatt agtgctacgc
     4021 actgaacaga tgttgcactc cagcgatgaa ttttggcggt gttgccaaaa atgggaattg
     4081 accattttgg atctccccac agcatattgg catcagttgg tcacggaact taaccctcaa
     4141 gacggacgta ttcctgctag tctgaaaact gtgattattg ggggagaaga agttcaacta
     4201 gaaaaagtga agcattggca tagttgcgtg gctcatatcc cccatttacc gcaattattt
     4261 aatagttacg gaccaacaga agcaacggtt atcaccaccc tacactacct caattcttca
     4321 gcagttactt ccgtttcgat tggacgacct ataagcaatg ctcaggttta tgttttagat
     4381 caatatctgc aacctgtacc tgtaggagtt cctggagaac tgcacattgg tggagtttcc
     4441 ttagctagag ggtattggca acgtcctgaa cttacggcag aaaaatttat ccagaatccg
     4501 attccttatg caacctgtga ccgactctac aaaacaggtg atttggggag gtttcgagca
     4561 gatggtaccc tggaatatct cggtagagtt gacgatcaag tgaagattcg cggcttccgc
     4621 atcgagttgg gagaaattga aacggtgcta cgtcaacatc cacaggtgcg tcaagctgtc
     4681 gtcattgcac gcgttgacat tcccggacaa aagcggcttg tggcttatgt cgtaccgcac
     4741 cagccgcaac caaccaccga tgaattacgt tattttctca aacagaaact gccaaattac
     4801 atggtgccct cggcgttcgt gctgctagaa gcgttgccga tgactcccaa ccgaaaggta
     4861 gactatcgcg ttttaccagt ccccgacttt tctcgcagtg tcgaagataa atttcttgcc
     4921 ccccgcacac ttacagaaga gaaattaaca gcaatctggt cagaaatctt aagactagaa
     4981 aaagtcggca tccacgataa cttttttgaa ctgggtggag actctatcct cagcattcag
     5041 ataatttccc gtgccaatca ggcgggtatc caaattgctc ccaaacagct atttaaatac
     5101 caaacaattg ctgagttagc tgctgtggca ggcatcactc gctctgttaa agcagaactt
     5161 gggttagtca caggtcaggt gatgttgaca ccaatccagc aatggttttt cgagcagaaa
     5221 ttgtccgaac ctcattactt taaccagtca gcactgctgg aagtgctgcc agattttaaa
     5281 tcagagcaat tgcagcaagt tgtacaacaa ttgttacagc atcacgatgc tttacgtctg
     5341 cgatttgtgc aggaagggga aaactggcaa caaattaacg ccgccacaca ggaatctctg
     5401 ccattgagtg tcatcgattt gtcgcacctt tcgccagaag aacagcaaac agcgatgaaa
     5461 gctgctgatg ctgaactcca agctagtctg gatttatcta ctggggcgat cgcacgaata
     5521 gcactgtttc aattgggcaa gaatcaacca ggtcggttac tgttaattat ccatcactta
     5581 gcagtagatg gcatttcctg gcgaattttg ctcgaagatt tggctaccgc ctatgaacaa
     5641 atcagccgtg gcgacgctat taaattacca ccaaaaacaa cttcctttca atattggagc
     5701 gatcgcctga cagaatatgg acgatcagag gcgatcgcca cggagttaga ttactggctg
     5761 agtgagtata attttaaagt tactgccttg ccagttgact atccttcaaa taaagaagat
     5821 aacaccgtag cctcaaccgc ttgtatgtca ctttctttaa ctgaagaaca gacccgcgcc
     5881 ctattgcaag atgtgccctc tgcttacaac actcaaatta atgatgtgct gttgactgcc
     5941 ttagtgcaga gtttttccca atggacagga gaacgttctc tgctgattga tcttgaaggt
     6001 catggacgag aagatttgtt tgaggatgtg gatttgtcgc gcaccgtcgg ctggtttacc
     6061 accttattcc ccgttcggtt acagctagaa gaaggtgacg atccaggaga ggctttaaag
     6121 ttagtcaaag aacaactgcg aggcatcccc aaccgaggta ttggttatgg tgtactgcga
     6181 tatttaaacg aaaacgccgc aatacgcaca aaactacaag cactacccca agcacaagtg
     6241 agttttaact accttggtca gttcgatcag gtgcttaagg catctgatgt gttgggtttg
     6301 gctaaagaat ttaaggctga acaaagttta ctcaataagc gcagccacct gttaggaata
     6361 agcggcttga ttcgcgctga aaaactagaa atgacttggt cttacagcga aaaagttcat
     6421 caaagaacta ccattgagcg tttggctttg gggtttatgg aagcattaaa aaccctgatt
     6481 gctcactgtc aatcacctga tgcgatcagt catactcctt ctgacttttc agcagctaaa
     6541 ctcagccaaa aacagttaga taaattccta gccaaaatca acaaaaacaa aaccaagaag
     6601 aggtagtttc gtggataata tcgaagacct ttatgaactt tcgcccatgc agcaggggat
     6661 gctctttcat accctttatg caccagaatc tgaaatttat tttgagcaat tgctttgcat
     6721 cctctgtggg gaattgaatt ttccaacctt tcaacaagct tggcagcaag ttgttgcgcg
     6781 acacccagtt ttacgcagtt ccttttattg ggaagagata gaaaagccct tgcaaatggt
     6841 gagtaagcaa atggaactcc cgtgggtgga actggattgg cgtcatttaa cacccaatga
     6901 acaacaacag aatttagagg attttttaga aggcgatcgc caaaaagaat tcgatctttc
     6961 tcaagctccc ctaatgcgct tcaccatcat tcagcttggg gaaaaaactt atcaatttat
     7021 ctggagtcat catcatattc tcttcgatgg ttggtcgatg cagattgtgc tgaaagaagt
     7081 tttagctttg tatgaagcta atcaacgagg cgaacattta cgcctacttc ccgctcgtcc
     7141 ctatcgagag tatattgatt ggttacagca acaaaatatt actcaggcaa agaacttttg
     7201 gcaacaaact ctccaggggt ttgaagttcc tactttattg ggagggaaca ggggacaggg
     7261 aaaatataac gagcagcgtt ttcaattatc ccaaacggta acagaaaaat tgcaatctgc
     7321 gacgcgacag caccatttaa ctttgaataa tttggtgcag ggagcatggg cgttactaat
     7381 ttcccgttac agtggggaaa gcgatgtggt ttttggtgca actgtatccg gtcgcccacc
     7441 gaatctagcg ggagtcgatt caatggttgg gctattgatc aacactcttc ctatacgggt
     7501 acaagttaca tccaagacag aattattacc ctggcttaag catttacaaa gccaagcatt
     7561 tgagcaggaa cagtatacct actactctct ggcagaaatt cagcgcctaa gtaatgttcc
     7621 cccaggaata ccactgttcg agagcctgtt agtatttgag aattatccgc tcgattctgc
     7681 tgaacaggaa agcaaaaaaa gcttagaaat tagtcatctt cgttgttttg aacgcacgaa
     7741 ttatccttta acggtagtgg ttaatcctga atcaaaattg tctggcagga ttatctatga
     7801 taccagtcgc tttgaggaac aaacaattga gcgcatgatt ggacattttc aaacattgct
     7861 acaaggaatg gcagccaatc tacaacaata tatttcccaa ttatctctgc ttagtgcagc
     7921 cgaagaagaa caattaattc tgcaagaaaa tcaacaaaaa acagcttcta ttcattacaa
     7981 atgtattcat actttatttg aagaacaagt agaaaaaacc cctgacgcag tagcagttgt
     8041 gtatgaaaaa gaatacttaa cttatcgaga tttgaataat cgcgctaatc aattagccca
     8101 ttacctacaa gcgctaggag ttaaacctga agtacgggtg gaaatttgtg tcgagcgctc
     8161 gcctttaatg gtggtaggaa tactcgctat tctcaaagcg ggtggagctt atgttcctgt
     8221 agattccgct tatccttccg aaagactaga gtttatgtta aaagatgtac aggcacccat
     8281 cttactaaca caaactcatt tgtgcgagca gctgccaatc gataatcaaa ctgtggtgaa
     8341 tcttgactca gattggaaaa taattgatca gtacaaagaa gataatttgc caagtgaagt
     8401 taatccagaa aatttagctt atatcattta tacatctggc tcaacgggaa caccaaaagg
     8461 aacagaagtt ccccatcgta gcatcattgg ttttatgttt ggggttgatt acattcaact
     8521 tgatgcaaac caaatttggc tacaacattc atcaatttct tgggatggac taaccctaga
     8581 actttggccg cccttgcttc atggggggcg ttgtgtactt tatcccgatc aaattcccac
     8641 accagagggc ttaagccgta tcatcactga acagcaagtt aataccctgt ttttgactac
     8701 agccctattc aatctcatga ttgatacaat gccggaaggt ttgttaggaa ttaaacaact
     8761 tttgacaggg ggagagtcag tttctgtggc tcatgttcgc cacgccttgg aactattacc
     8821 ggaaacccaa attattaatg cttatggacc ttgcgaatgt acagtaataa cctcttgtta
     8881 tccaatttcc aaacaacttg gtcaaaatgt ccattcaatt cccattggaa aacccattgg
     8941 tgataggaca gtttatctac tagatagaga tttacacaga gttccgattg gcgttcctgg
     9001 cgaactttat gtgggtggcg cgagtgttgc tagaggttac ttaaatcaac caaccttaac
     9061 ccgtgaaaaa tttattccta atccttttct tgaaggtgat acactttaca aaactggaga
     9121 tttagtccgc cgtcttcctg atggaaatct ggaattttta ggtcgaattg atacacaggt
     9181 aaaaattcgt ggttttcgta ttgaattaga agaaattgaa gcagttttaa atcaaaatcc
     9241 tgacattaaa caagtcgtag ccattatacg agaagatgaa cctgggaaca aatacttagt
     9301 tgcctatctc ctaaccacgg acaacccacc aactgctagc actctgcgaa acttcctcaa
     9361 tcaaaagctg cctgactaca tgattccctc tgctttcgta tttcttgagg aattccccct
     9421 cacgcctaat ggtaagataa atcgccgtgc tttacctgct ccagatgctt cccaaagaaa
     9481 tctagaggtt gattttgttg ctccgcgcac gcctactgaa caagaattag ccatgatttg
     9541 gactgaagtt cttaaattaa aacaaattgg aatttacgat aactttttcg agttgggtgg
     9601 acattcttta ctggctaccc aagttgtttc tcgattaaga gaagtctttt ctctagattt
     9661 tcctctgcgt tatgtgtttg aaaatccgac cattgctgaa ctagcccaaa aagtgattga
     9721 tcaacagatt gaacaagcag aaaatgatga gctaacacag cttttagggg aagttgagca
     9781 gttatcagaa gaagaagtga cccagcaatt acttttttga gtattaacag tactcttttt
     9841 tatttttctg tgttctctgt gcctctgtgg ttctattcaa aaaaaactaa ttttcaacaa
     9901 taagtttaaa caataaatat tatgagcgat atactaaaac gtcttgaaac cctttcgcca
     9961 gaaaagcgag aattagttct acaaaaactg aaaaagcaac agcaatcttc acaaaatgac
    10021 cacaggttaa ctccccccct cacacccgta tcgcgggaac aaccccttcc tctctccttt
    10081 gcccaacaaa gattgtggtt tcttgaccaa ctagaagggg aaaattgtgt ctacaatgtc
    10141 ccgtttttct ggcaaattag cggatttctg aatatcagtg ctttagaaca agcgatcgca
    10201 gaaattgttc aacgtcatga agtcttacgt actagtttct cagttgtcga tgaatcgcca
    10261 atacaggtga ttcacgctaa tccccagctg acaatacaag tactagactg gcgacaatta
    10321 acagaaaaag accagttaaa gaaagcccac cagttagcga cagaagaatt gcaacaaccc
    10381 tttgatttat caaacccacc tttgttgcgg gtaaagttgt tgcaactaac tgaccaatcc
    10441 catttgttgt tgcttgtcat ccatcatatc gtttgtgatg gctggtcaat ggacatcttc
    10501 cgccgtgaat tgttcaccct ttataccgca ttttgcgccg taaaaccgtc tcccttacca
    10561 gcattaccgc tacaatatgc cgatttcgct cattggcaaa gacaatggct acagggagag
    10621 gtactgcaaa cgcaactcaa ttactggcaa aaacaattag ctgaagtccc gcctctgtta
    10681 gaattaccta ctgataaacc gcgtccatca gtgcagagtt tcagggggcg tagcgagttt
    10741 ttgaaactca atcaagattt aacacagaag ttgaagcgtt taagtcagga gtcaggaaca
    10801 accttgttta tgactctact ggcagcattt acgctgttac tgtcgcgcta cagtagacaa
    10861 gaggatattg tggttggttc tgcgatcgcc aatcgcaacc gtcgagaaat agaaccactg
    10921 attggctttt ttgtcaatac cctagctttg cgtaccaacc tgcaaggaaa tccaaccttc
    10981 ttagaattac tcaaccgggt aaagcaagta actctggatg cttatgacca tcaagactta
    11041 ccttttgaga aattggttga tgaattgggc atagagcgat cgctttctca tcatcctctg
    11101 tttcaagtcg cttttagctt gcaaaatgca actcaagaga aattagaaat tcctggatta
    11161 actctgactc gttttgagtg ggaaaacacg acgacactgt ttgatttgtc gctgattttt
    11221 cgagaaacgc ttcagggatt gatcggagaa tgggaatatg cgacagattt gtttgaacct
    11281 acaaccattc aacgaatggc aggacatttt gaagttctgc ttcaggcaat tgttgataac
    11341 cctcgacaac ctatcaatac tctgccttta atgacagcgg cggaagtgct gcaactacaa
    11401 tgctggaatc aaactcaaat tgaatatcct gaagataaaa ctctagttga cttatttgaa
    11461 caacaagtta aaaaaaatcc tcataatatc gctttggtgt ttgaatctca aagcttgact
    11521 tatcagcaac ttaatcaaaa agctaaccaa ttagctcatt atttaattca aaatcaccaa
    11581 attcagccag ataccttaat tagtatttgt gtcgaacgtt ctattgagat gattattggt
    11641 ttactcggta ttctcaaagc aggtggggct tatgtgccga ttgaccccaa ttatcccaaa
    11701 cagcggattg ggttcatgtt agaagattca gggacatcgg tgttgctgac tcaaagtttc
    11761 ctcactgagc aattaccact aactgaactg gaaaactcgc ctaagattat ttgtttagat
    11821 caagaaactt ttgcccaaga gttaacagat aatcccagtc ctcaaagtac accattagat
    11881 ttggcttatg cgatctatac ctctggttcc accggacaac ccaagggagt aatgatttcg
    11941 catcgaggac tggtgaatat gactttggca gttgagcaaa ttttgcttct tcaaccccaa
    12001 agccgtgtgc ttcagtttgc ttctttcagc ttcgatgcct caatttcaga aattgctact
    12061 gccctcgccg caggcacttg tttgtatctt gctaaaaaag aaaccttgtt acccagtcaa
    12121 agcttggttg acttcttagc tgaacacaaa attacccaca gctttttgcc tccttcagct
    12181 ttatctgtct tacctcaagc taccttaccg gatttgcaaa ccataggggt tggtggtgag
    12241 gcttgcccag cagaattagt tacccagtgg gcacagggac ggcgtttctt taattgctat
    12301 ggaccaacgg aatctacggt gaatgctgcg atcgctctag ttcaacccaa tggcaaaaaa
    12361 ccgcctatcg gtaaaccgtt gcccaatatc cgcatctata ttttagatgc atacaatcaa
    12421 ctattacccc caggaatacc aggagaattg tgtattgctg gagttggttt agctagaggc
    12481 tatctcaatc gtcctgaaac tactgccgaa aaatttctgg aagttgagtt attcgggaaa
    12541 atcgagcgaa tttacaaaac tggcgacttg gcaagatgga actctgatgg aaaccttgag
    12601 tatctgagtc gtattgacga tcaggttaaa ctacggggct ttagaattga actcggtgag
    12661 attgaatcaa ttttattaca acatccatca gttaaagaag ctgtcgccat tttatctgaa
    12721 gctgataata atcccaggtt agtggcatat gtgacgacgg agaaatccgt caatttaggg
    12781 ggtcaattca aggactacct gaaaactcgc ctaccgaatt atatggttcc tagccagatt
    12841 ttggtattag ataaattccc ccttagccct aacggtaaac tagatcgtaa agccctacca
    12901 gcaccagatc cagctacttc caatgacttt gaaatgcctg taacttccac agaagaacta
    12961 ctggctactt tatggcaagg tttgttaaaa gttaagtctg ttggtcgccc tgacaacttc
    13021 tttgaactgg gaggacattc cctattagca acccaattgg ttgtccgtat tcgtgacagt
    13081 tttggggtag aattacctgt ccgcaaggta tttgagcaga gcgttttgtc tgagttggct
    13141 acagttattg acaaagctgc ttccgggttc accctacctc cgatcacagc acagccagaa
    13201 aatgaaccca aaactctgtc ctttgcccaa tcaagactct ggtttttagc ccagcttgaa
    13261 ggtaaaggca cttcggctac ctacaatatg tcagcggctc tgcaacttga cggcaatttg
    13321 tgtatggaag ctttgcgtgc aagttttgag tatctcctcg aacgccatgc tattttacgc
    13381 acctattttc ctgcactgga tggacaacct caagtcgtcg tcaaaaatct agaggatata
    13441 gaagtgctgg agatcgtaga tttacgggaa gcgcctcagc aaagaacgga aattgtacaa
    13501 cgtttagtcg atactcatgc tcaagaaccc tttgatttaa atactggtcc cctgttcaag
    13561 gcaaaactgt tgcaacttag ccaacagaaa aatgtgctgc tgctcaatat gcaccacatt
    13621 atcagtgatg gctggtcaat gggtgtgttt aagcgcgaat gggaacaggc ttatgctgct
    13681 tttgctgcgg tggatactcc aaatttgtca ccattgccaa ttcagtatag tgattatgca
    13741 gcttggcagc gaagctggct acaaggtgag attttagaaa gtcaggaaaa ttactggaaa
    13801 caacaactag gcgatgcccc ccgattgctg gatttgccta ccgatcatcc ccgtccagcg
    13861 caacaaagtt atcaaggtgg gcgcgaggaa tatcgtttaa gtagtgaact gacttcatta
    13921 cttaaaacag tgagtcagaa acacggggtg agtttgttta tgaccctgtt aacagctttt
    13981 agtattttac tatctcgtta tagccgccaa gaagacttat gtgtcggtat tgcgatcgcc
    14041 aaccgtaccc atagctacac agaagggtta atcggctttt ttgtcaatac tttggtattg
    14101 cgaagtcaag tcaaaccaga gcaaggattt agcgagttac ttcaacaaac ccgccaaact
    14161 tgcttagatg cttatgctca tcaagatatt ccttttgaat atttggtaga acagttgcaa
    14221 ccagaacgca gtctgagcca taacccctta ttccaagtga tgatggtgtt gcaaaacgcc
    14281 gtaggggcgg gggcgaatgt tagtttacca gggcttgata ttcaatattt ggaacaaagt
    14341 ttcccgtttg ccaagtttga cctgacactg gatctttgtg aaaggggcga ccaactgcat
    14401 tgtatgtggg aatatgccac agatttattt gaggctgaaa caattaggcg catggcagga
    14461 cactttgaag tcttgctgac agcaattact caaaatcccc aacagcctat cagtaaacta
    14521 cccttaatca ctacagcaga aatccaacaa ctgctaacct ggaatcaaac cgataccgat
    14581 taccctcaag accaaacact ggtgactttg tttgaacaac aggtagcaaa aacaccagat
    14641 aacattgcgg tcgtgtttgt agacgagcgc agcgaggctt ctcgcagagt agagcacagc
    14701 ttaagttatc aagaattaaa tcaaaaagca aatcaactgg ctgattattt gttgcaactg
    14761 aaaaaagaac aacaattgcc tgacaaccca ttgatcgcga tttgcatgga gcgatcgatc
    14821 tctatgattg ttggtattct tggtatcctc aaagcaggtg gggcttatgt gccgattgat
    14881 ccgagttatc cccaagaacg cattcattta atgctcgaag atagtaatgc ttctgtatta
    14941 ctaacaacaa accccatcaa aaagccactt tcccttgaaa aactgcaaaa gacctgtcat
    15001 gtagtgtttt tagagcaaga aacatgggtc aatcagccaa cggacaatcc caacttacaa
    15061 agtcgttctg atgatttggc ttatgtcatt tatacttctg gttctacagg aagacctaaa
    15121 ggtgttgcga tcgcacattc tagtccggta gttctggtaa agtgggcgca ttcagttttc
    15181 agtgcagaac agcttcgagg tgtcttagca tcgacctcaa tgtgtttcga tctgtccatt
    15241 tttgaaattt ttgtgcctct aacgcaaggt ggtagcgtca ttgtggtaga aaatgcactc
    15301 tacattgagc aagcatccaa cagtattgtg ccgataacat taattaacac tgtgccgagt
    15361 gctgctgcgg aactgctgaa aatgaatgct attccatcca gcgtggaggt aattaattta
    15421 gctggcgaac cattaaaaaa tactttggta caggctttat atcaaaccac atctgtaaga
    15481 gaagtttata atctgtacgg cccttctgaa gacacaactt actcgacttt tacaaaagtt
    15541 gctaaaaatg cccagcacga accaactatc ggtaaggcga tcgccaacac ccgcatctat
    15601 attctagata gctataacca actccttccc cctggcattc caggggaact ctgtatcgct
    15661 ggtgcgggtt tagcacaagg ctatttaaat cgtcccgatc tcagtgctga aaaattcatt
    15721 aacctcaagc tgttcaacca aactgagcga atttataaaa ctggtgatct agcccgttgg
    15781 ctacctgaca gcaatttgga atacttaggt cgcatcgatc atcaggtcaa agttcgtggt
    15841 tttcggattg aattaagtga aattgaagcg tcattagtca aacatccaaa aattcaggaa
    15901 gcagttgtta ttgttaggga agaaactgat cttgataaac gtttggtagc ttatatcgtc
    15961 ccaacagcaa cagatcagca cacaagccaa ggtgaagtgg tggaattgtg ggaacaaatt
    16021 tttaatgata gctactctca gcaacaagcc ccaaccgatg acccaactct taatttagca
    16081 ggttggaatg atagctacac agcacaaccc attccccaaa cagcaatgca ggaatggcga
    16141 gatacaacag ttgaccaaat tctggaactt gaaccgaaac aagtttggga aattggttgc
    16201 ggtacaggga tgttattatt tcaaattgcg cctcattgtc agcattatct gggtacagat
    16261 ttttcaccag acgcattgca ctatatagaa caacatctta aacagcagtc tcttaatgac
    16321 agagttacct tgaaagcaag tgcagctaac cagtttgacg gcattgaaac aaatgcttat
    16381 gacttggtaa ttatgaattc tgtcatccag tattttccct ccttggatta ctttttggaa
    16441 gttttgcacg gagctgttaa cgctgtgacg actcaaggag caatctttat tggggatgta
    16501 cgaaatctca atctgctgga ggctttccac accgcagttg aattttatcg cgccgccgat
    16561 gaattatcaa ttaaggactt gcgtcaacag attcaaaaaa gtatccgtaa tgaaggtgaa
    16621 ttactaattg accctgattt ctttatcgcc ctcaaacaac gaattcctcg gattagtcat
    16681 gtgcaaattc aattgaagcg aggttttgct caaacggaaa tgagtcgttt tcgttatgat
    16741 gttgttttac acttagatcg ggcagatact tccgtcgcgc aatctcaatg gttagattgg
    16801 caagaccaac agctgaatct ggaaacaatc gagaaaattt taacaactca gcaaccggat
    16861 ttgcttggca ttaagcatat tcctaatgca cgtctgacct cagaaatggt gctgttagaa
    16921 caaattgctc aattagaagg tactgtttca gacttaaaag cagcagttgc acaagccaaa
    16981 ttagggatag aacccgaagc gttccgagct ttaggacaag atttacctta tacacctttt
    17041 atacaatata gctccacagg attttctaat tacgatgttg ttttccaaag gaatgtccct
    17101 ggacaggtga ctttaccacg attcccaaca acagataatt tgcggctgaa accttggcaa
    17161 cattacgcga accaaccgct gcaatatcgc accaatcaag ttgatccagt tttattagaa
    17221 gaatggcggg attttctggg caaaactctc cccgaatata tgatccctaa ccatttcact
    17281 gtcttagaaa aactaccact gacaccaaat ggaaaagtag accgcaaagc cttaccagcg
    17341 ccagatatag cagttccagc cacagacatt gaattacccg taacagagac agaaaaattg
    17401 ctggctcaat tgtgggcaaa gctgcttaaa tatgaagcga tgcctgcggc gggctacgcc
    17461 tacgcccgcc aggataactt tttcaacttg gggggacatt ccctattagc aacccaactt
    17521 attgcccgta tccgcgacac cttcaaagta gaactgccac tgcgtaaggt atttgagtac
    17581 cctaccctca gtgaattggc gaattatctc gatacctgca tttgggttaa ttccaccgac
    17641 gaaagtatgc agcctctcaa cccagacgag gaggaaatcg aactttaaat tatcacagtt
    17701 gaaaacacgt cctcaagtaa aatttatctt ttcatcataa acttaaccta tgattgccct
    17761 atctgattcc atttttctga ctcccgaagc atacctgcaa ctagaagaaa aaaacaatat
    17821 caaacacgaa tatattgatg gtcaagttta cgcaatggcg ggaacaactg acacccataa
    17881 caccattggt ttaaatctcg ctttattcat tcgtaaccac ttccgaggtt cagactgtcg
    17941 agtttacttt gccgatgtta aagtcaacct tgaaagacgt aaccgctttt attaccctga
    18001 tatcatcgtt acctgcgacc ctaaagaccg agaaacctcc acttataaaa tctttcctaa
    18061 acttattatt gaagtcctat ctgagtccac cgaagccttt gacagaggtg acaaattcaa
    18121 cgactatcaa actcttgaca gcctagaaga atacgtttta gttaacagca aacgccaacg
    18181 atttgaaaca tttcgttgta atgaccaagg actatgggtg ctacaaactt atacacctga
    18241 tgaccaaacc tttgaactcc aaagcattaa tctaacagct tcttttaccg acctttacca
    18301 ggatgtagaa ttggaagcga tgtctacgac gggctacgcc aacgccccaa aaccagatct
    18361 gagttaaaga ttgtaaacat tttaaaatcc ttactactta ctgttaagaa ttactttttc
    18421 atatcgacag tcaagtttga ttatgtctga ctaaatatta tgacaaaaaa tatgacaaaa
    18481 aataagcagg tagtttcttt aatgcttcgt ttgcagaaca tgggctgccg aatttgggct
    18541 gaagatgata agttacggat tcgtactagc aaaaacgccc tgacttctga actcaagcag
    18601 gaaattcaaa acaacaaagc agaaatatta gcatttttaa atgctgccaa agccaaaact
    18661 attatggcag aggaaattcc cactttaagc gctgatgccc cgaaatttct ttcctttgct
    18721 caacaacgcc tctggctgtt agcacaactg actggaccat cagctactta caatatgccg
    18781 atggctttac agttggaagg caaccttaat attgatgcgt tgcgctctag tttggcttat
    18841 ctgcttaacc gtcataccag tctgaggatg tattttccta cagtggcggg acaaccgcaa
    18901 gtcctgatcc aagatttaga caaaatcgaa gttctagcag tactagactg gcaaaacctt
    18961 aatgaacatc ctaactcgcc aaccgttcag cgtttaatcg atgctcatac tcaagaaccg
    19021 tttgacttaa atactggccc tttgtttaaa gctaaactgc tacaattgca agaacaaaaa
    19081 tatgtgttgc taatcaatat gcaccatatt atcagtgatg gctggtcaat gggagtattt
    19141 gttcgtgagt tacggcaagc ctataccgcc tttacccaaa gtcaaacccc aaaccttgct
    19201 cccctaccca ttcaatacag cgactatgca aactggcaac gaaactggtt acaaggggag
    19261 gtattagaaa accaaatcga ctactggaaa catcaactcc aggatgcttc tccattactg
    19321 gaattgccaa ctgattatcc tcgcccagca cagcaaagtt accgaggcga tcgctatctc
    19381 tactctctca cgccggaatt aagtgctgcc gttaatactt tcagtcaaca acaaggcgca
    19441 agtctattta tgatcttgtt ggcagcttta agtcttctgc tttctcgtta cagtcgtcaa
    19501 aacgatctgt gtattggttc tcccattgcc aaccgtaccc atagtcaaac tgaatcatta
    19561 attggtttct ttgtcaatac tttagtactg cgtactcaaa tcaagcctga gcagagtttt
    19621 atcgagtttc tgcaacaaac tcgctcctct tgtttagatg cctatgccca tcaagacatc
    19681 ccctttgagc ttttggtaga aaagttacaa ccagagcgca gcatgagtca taatccatta
    19741 ttccaggtga tgttagcgct ggaaaataat gaaagtccag acctgagttt accaggatta
    19801 gagattcaat ggctgggagt caagggtgcg atcgctaagt ttgatttaac acttttggtg
    19861 atggaatatg acaatcagtt aaattgctct tgggattatg ctaccgatct ctttgagaag
    19921 agtactatcc aacggatggc agaacagttt gaagttctgc taaaggaaat tcttgataat
    19981 ccgcaccaac cgatcaacac tttgcctttg atgacagcaa ctgaattgct gcaactacaa
    20041 cgctggaatc aaactcaaac cgactatccc caagataaaa ctttagttga cctgtttgaa
    20101 gcacaagttg aaaaaaattc tcagaatctc gctttagtct ttgaatctca acagctaact
    20161 tatcaacaac tcaatcaaaa agcgaaccaa ttagctcatt atttaattca caattatcaa
    20221 attcatccag atactttaat tagtatctgc gttgaacggt cattggagat gattattggt
    20281 atactcggta tcctcaaagc aggtggggct tatgtgccga tcgatcccaa ttatccaact
    20341 gagcgtattc agttcatgtt agaagattct gggacatcgg tgttgctgac ccaaagttac
    20401 ctcactgatc aattaccact aactgaactg gaacacccac ctcaggtaat ttgtttggat
    20461 gaggaaactt ttgccgaaga gttaacagat aatcccagtc caaaaagtac gcctgatgat
    20521 ttggcttacg tcatctatac ctctggttcg acgggaagac cgaagggggt gatgatttcg
    20581 catcaaggac tggtgaatat gactttggca gttgaccaag ttttgcaaat tcaaccccaa
    20641 agccgtttgc ttcagtttgc ttctttcagc ttcgatgcct caatttggga aattgctact
    20701 gccctcgccg caggggcttg tttatatctt gctaaaaaag aaaccttgtt acccaatcaa
    20761 gacttagtga actttttagg cgatcgcaaa atttcccatg tcacgttacc tccttcagtc
    20821 ttatccctat tacctcaagc gacgttacct aatttgcaaa ccgtagttac tgctggtgaa
    20881 gcttgcccaa cagaattagt tacccgatgg gcaaaaggac ggcgtttttt taatgcctac
    20941 ggaccgacgg aatctacggt ttgtgccact atagctctag ttcaacccaa cggcaaaaaa
    21001 ccacctattg gtcaaccgtt gcccaatatc cgcatctata ttttagatgc aaataatcaa
    21061 ctattacccc caggaatacc tggcgagttg tgtatcgctg gcatgggttt agcaagaggc
    21121 tatctcaatc gtcccgattt gactgctgac aaatttcttg aagttgaatt gtttggtaaa
    21181 actgagcgaa tttacaaaac tggcgacttg gcaagatggg gagatgatgg caaccttgaa
    21241 tatctcggtc gcattgacga tcaggttaaa ttacgaggct tccgcataga attggctgaa
    21301 attgaagcga gtttgttgca acacccttta gtaaaagaag caattgtcac cttatataaa
    21361 actgagaata accagagttt aattgcctat gtaacgggaa tgaccactga tttgcctacc
    21421 caattaaaaa atcacctcaa atcccgtcta cccgattaca tgatacctgc tcagattatc
    21481 gtactggata aattgccttt aactcccaat ggcaaaattg accgtaaagc tttacctgtt
    21541 cccaattttg aagttggaag ctcatataca gccccgcgca atcaagtgga aaaacagcta
    21601 gcacaggtat ggtctgctgt actcgaacgt caagaaattg gaattcatga taactttttc
    21661 gacttgggcg gtcattcttt attagcaatg aaattgctca ataatattca acaggttttt
    21721 gaccaacaac ttggcttgag cagtttattt cagaatccta ctattgctca actggcacaa
    21781 caactcggta atactgaggt gcaacagtcc catgccgatt tactatcact ccaacctcaa
    21841 ggagatgccg tccctctatt ttgtcttcct ggcgcaaacg gacacggttt ctattttcga
    21901 gatttagcca tcaatttagg aaatgagcag ccagtgtatg gactcgaaac tccaggaaga
    21961 gacggactga atgcactccc tgattcagta gcagcccatg ccactcaact gatttcgcta
    22021 ttacgtcaac agcaagcgaa aagtccatat atactagcag gatactcttc gggttgtgct
    22081 gttgcttttg aaatggctgc ccaactcgaa cagcaaggtg aaaaagtggg tttactagct
    22141 atcttggatt ctgcactggt ttctcagcct gagtatttaa ctgatagagc agatattgat
    22201 tggatttggc aattactcca acggattgaa gccttaaagg gagtttcttc aggtttgaaa
    22261 tacgctgatt tagctgctca acctgacgat caagcccgtt gggatttggc ggcggagtat
    22321 gtataccgat ataacgttct accggaacac gcaagccttt ctttactcaa aaccaatatg
    22381 caagtgatga aagtgctgac gctcaattac gcgaattatc agcctaatca tcgaatttct
    22441 gcccccattg ttttattccg cgctcaagaa gttcatgaaa ttcttttgca agaactccaa
    22501 gctatttccg attacgattt accagattgg ggatggcaag cttatactca aaaacctgtt
    22561 aaggtgatat ctgtacctgg aaaccacggt cgaatgcttt ctgagcctaa tgtaaaaatt
    22621 ttagccagag aattactaaa caccataaaa taattttacc aaagttctaa tggaaattat
    22681 cgttgtattg agcctaaact aatttttaaa atatgcaatc tacaactttt gttaagaaaa
    22741 cttcaacgaa tgattcttct ccgggtttta atcaattttg ggagaatgtc agagcactaa
    22801 caggatctta ctggtatcca acagaggcag gaggaagagc attttcagat gttcttcgtt
    22861 catggggaat gcttattctc ctgatattgt taatcgtcat gctcgtagct gtaactgtct
    22921 ttaatagctt cattaaccgc tatttgcttg atatcctcgt tgaagaaaaa gaacctacta
    22981 aacttgttca gatattatgg ctttacggtg gtgctcttgc ctgcgtaacg ctcttaatag
    23041 gattgtctaa atttgttaga aaaaaaatcg ctcttgattg gtatcaatgg ctaaataatc
    23101 agattttaga aaaatatttg agtcatcgcg cttattataa aatcaacttt caatcagatg
    23161 ttaataatcc agatcaacga atagctcagc aaatcgaacc tctgaccagc aatgctctca
    23221 gtttttcggc tacttttcta gaaaaagtgc tggaaatgtt aactttttta gtaattatct
    23281 ggtctctttc caaattgatt gcaattgcat tgattgttta taccattata ggcaatgtaa
    23341 ttgctgttta cttggctcaa gaattgaata agattaaaca agaagaacta gaatctcaag
    23401 cagactatac ttacagtatc actcatgttc gtaatcatgc tgaatcaata gctttttttg
    23461 ggggagaaaa tcaagaatca aatataattc aacgaagatt ttatcagatt attaaaagta
    23521 ctaaacgcaa gattgattgg gagagaagtc aggatatttt taacagagga tatcaggcga
    23581 ttatccaaat atttccattt atagtattcg gtcctttaca gattagaggt gaaattgatt
    23641 ttggagtaat tgcccaagcc agtctagcgt gtaatttgtt tgccactgca atcgcagaaa
    23701 taatcagaga atttgcaaat tcaggaagat tttctagtta tgttgagcgt ttaactgagt
    23761 tttcaaatgc tttagaagaa gtgactaaac agcccgaaaa tgtgaacaca attaaaacaa
    23821 tagaagaaaa ccgtctggct tttgagaatg ttaccttaca aacgccaaac tatgaacagg
    23881 tgatcgtcga agacttgtca cttgttgttg aaccaggaga aggtttacta attgttggac
    23941 caagtggacg aggtaaaagt tctctgttga gagcgatcgc tggtttgtgg aacgcaggta
    24001 caggtcgtct ggtaagacca tcgttagaag aagtcttatt tttgccccaa cgtccttata
    24061 taattttggg aactttacgc gaacagttac tctatcccaa tacaaatcgt caaatgagcg
    24121 atgcagaact cgaagaagtt ttgcgacaag tcaacttgca aaacttgctt acgcgaatcg
    24181 aaagctttga tacagaagtc ccttgggaga acatattatc gctgggagaa caacaacgct
    24241 tagcttttgc acgattgtta attactcatc ccaactttac tattttagat gaagcaacca
    24301 gtgctttgga tttgacaaat gaaggctatt tatatgaaca actccagtca acaaaaacaa
    24361 cttttatcag tgttggacat cgagagagtt tgtttaatta tcatcaatgg gttttggaac
    24421 tttcacaaga ttccagttgg cgacttttga ctgttcagga ttatcgcctt caaaaagcca
    24481 acgaaattat tactaaccct cccgacaact ctcaaattac agaagccaac gaaattatta
    24541 ctaatcctcc cgacaactct caaattacag aagtcaacga aattattact aatccccccg
    24601 aaaacccttc gactacgctc agggtaaacc ctcaaattac agaagccaac gaaattatta
    24661 ctaacccccc cgaaaaccct tcgactacgc tcagggtaaa ccctcaaatt acaatagatg
    24721 tttcaccaca gaatcaatcc ttagagccac cagaaaccag cacaatttca gggctttctc
    24781 ataaggaaat gcaaatatta acaggcgtta gtattaacac tattagaagc aagggaagtc
    24841 ttggcaagac tatcacaacc aaggatggcg tgacttaccg ttatgacaaa gatcccaacg
    24901 tgttaaaatg ggtcagagtt tag
//
