BGC0002514: julichrome Q6.6 biosynthetic gene cluster from Streptomyces sampsonii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 16,028 nt. (total: 16,028 nt).
This entry is originally from NCBI GenBank MT799798.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002514
Short description julichrome Q6.6 biosynthetic gene cluster from Streptomyces sampsonii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MT799798.1
1 - 16028
via Knock-out studies
Compounds
  • julichrome Q6.6
Species Streptomyces sampsonii [taxonomy]
References
Chemical products information
julichrome Q6.6 Evidence:
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QNL10604.1
  • juiO
1 - 846 (-) NmrA family protein
    copy AA seq
    copy Nt seq
    • QNL10605.1
    • juiN
    887 - 2347 (-) FAD-dependent oxidoreductase
      copy AA seq
      copy Nt seq
      • QNL10606.1
      • juiM
      2456 - 3619 (-) Acetylase
      • Acetylation
      copy AA seq
      copy Nt seq
      • QNL10607.1
      • juiL
      3661 - 4662 (-) Reductase
      • Reduction
      copy AA seq
      copy Nt seq
      • QNL10608.1
      • juiI
      4675 - 5901 (-) Biaryl bond-forming enzyme
      • Biaryl bond formation
      copy AA seq
      copy Nt seq
      • QNL10609.1
      • juiK
      6055 - 6759 (-) TetR family transcriptional Regulator
        copy AA seq
        copy Nt seq
        • QNL10610.1
        • juiJ
        6971 - 8434 (+) MFS transporter
          copy AA seq
          copy Nt seq
          • QNL10611.1
          • juiG
          8910 - 9563 (+) Response regulator
            copy AA seq
            copy Nt seq
            • QNL10612.1
            • juiH
            9809 - 10480 (+) Polyketide synthesis cyclase
              copy AA seq
              copy Nt seq
              • QNL10613.1
              • juiA
              10477 - 11748 (+) Beta-ketoacyl synthase
                copy AA seq
                copy Nt seq
                • QNL10614.1
                • juiB
                11745 - 12935 (+) Beta-ketoacyl synthase
                  copy AA seq
                  copy Nt seq
                  • QNL10615.1
                  • juiC
                  13028 - 13291 (+) Acyl carrier protein
                    copy AA seq
                    copy Nt seq
                    • QNL10616.1
                    • juiD
                    13358 - 14143 (+) Ketoacyl reductase
                      copy AA seq
                      copy Nt seq
                      • QNL10617.1
                      • juiE
                      14173 - 15123 (+) Cyclase/dehydrase
                        copy AA seq
                        copy Nt seq
                        • QNL10618.1
                        • juiF
                        15120 - 16028 (+) Thioesterase
                          copy AA seq
                          copy Nt seq
                          Biosynthesis information

                          No biosynthesis information available for this record.

                          Annotation changelog

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          MIBiG v4 annotathon
                          • (ID: P75FRHHCFPTCPYSP65VDVPHW)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          Added chemical structures for compounds: julichrome Q6.6.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Added NPAtlas links to compounds: julichrome Q6.6.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Renamed compounds: julichrome to julichrome Q6.6.
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          Entry added
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Similar known clusters from MIBiG 4.0
                          Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                          Detailed help and explanations are available here.

                          Click on reference genes to show details of similarities to genes within the current region.
                          Double click on a reference drawing to reverse the display of the genes.

                          Click on an accession to open that entry in the MIBiG database.


                          Location:

                          Identifier
                          Identity
                          Coverage
                          Detailed domain annotation
                          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                          A domain glossary is available here, and an explanation of the visualisation is available here.
                          Selected features only
                          Show module domains