LOCUS       BGC0002524              5092 bp    DNA     linear   BCT 04-JUL-2020
DEFINITION  Bacillus sp. Xin1 bacicyclicin XIN-1 biosynthetic gene cluster,
            complete sequence; and BacE (bacE) gene, complete cds.
ACCESSION   BGC0002524
VERSION     BGC0002524
KEYWORDS    .
SOURCE      Bacillus sp. Xin1
  ORGANISM  Bacillus sp. Xin1
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:54:22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5092
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1182)
                     /gene="bacE"
     CDS             complement(1..1182)
                     /codon_start=1
                     /gene="bacE"
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 87.2; E-value:
                     1.7e-26)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:Prodigal:002006"
                     /inference="similar to AA sequence:UniProtKB:O31710"
                     /product="BacE"
                     /protein_id="QLA09665.1"
                     /transl_table=11
                     /translation="MFRKIGFIIKQKKIVIGIVLLCIFFAATNIFMVQGKAKSEKNADI
                     SFQKVTERSLNNTKLISGQVKPGNIESFYADPTKGKVKDIAVKEGQEVEKGTKLFSYDN
                     EEINLQLKQAALDQKMATMRYDQGKKKIDSLKKEIKKAKDSGAGKEVTDPMEEQVNELE
                     MQQKTIDLEKEKGELQSQELKKKQGKLTIYSNFAGVVQKLDKDAAQSSAQAMGGQGKSF
                     LQIASKDPFQIQGTLTELQKSQIQKDQTFIATAKANSKQKWTGKITEISEFPTSAEMAQ
                     AADAGEGTQNMSQYTYKASLDGQEGLSPGYHVSLQVSLENKKMIAVLSKSIVEKDGEPF
                     VYVEEKGKLRKQNVKKGSTDGDWTEVLEGVTVGQKVVKNPSDNVYDGMEVKEK"
     source          1..5092
                     /country="China"
                     /db_xref="taxon:2740676"
                     /mol_type="genomic DNA"
                     /organism="Bacillus sp. Xin1"
                     /strain="Xin1"
     misc_feature    1..5092
                     /note="bacicyclicin XIN-1 biosynthetic gene cluster"
     subregion       1..5092
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRPS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5092
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1484..2950
                     /gene="bacB"
     CDS             1484..2950
                     /codon_start=1
                     /gene="bacB"
                     /inference="ab initio prediction:Prodigal:002006"
                     /product="BacB"
                     /protein_id="QLA09666.1"
                     /transl_table=11
                     /translation="MIHNKLLIIKLTILNQFRQSMDIKSKELKKEYPYIPMKIIPIITL
                     ILCIMGLIVPLITSVILASLLIYTNDYIYSLYIYIYIYNLKNLINKFEINSGKINERIS
                     FIKYSSNKYLYNLFKIYNPINFIPIIIFLLSFLIKAILNQDIIFTFLIISCILTIYFIT
                     KRIDVFFQLLSLVNFSYISYILHSISSEIKWNNILKIDYFIKDNKNIIKLDWNQIFTYY
                     FSSILLLSLTSLLIYKLINNINKTNKNIKKEKKMKKNLSKDILVYLNFSNSLTLNRKLS
                     LWIPLGPMMIISIPLFINIPSQKYLFIIFMGIIVCLYTKRFMYQYTYFFHYFTNKKEKQ
                     LFKLNFKNLFNILKTKLLILLINQLTLIIYIYGLYITIFWNNIQFTDLLILTFVYIVSL
                     TIPLSEKKFIIFDFQTLKLNKDNDYGGTMEVLYSMCLIILFFVNLGLEVNNIKFDISFL
                     TILLPFLFLIFSVTKVYLNIKIWGIHHENN"
     gene            2937..3119
                     /gene="bacI"
     CDS             2937..3119
                     /codon_start=1
                     /gene="bacI"
                     /inference="ab initio prediction:Prodigal:002006"
                     /product="BacI"
                     /protein_id="QLA09667.1"
                     /transl_table=11
                     /translation="MKIINYLFLAILFIFQIHQILKHRYAYKNTQKKYHKNMVIVFSII
                     LVLTSISIIATYLNI"
     gene            3161..3790
                     /gene="bacT"
     CDS             3161..3790
                     /codon_start=1
                     /gene="bacT"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 71.9; E-value:
                     1.1e-21)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:Prodigal:002006"
                     /inference="similar to AA sequence:UniProtKB:P71009"
                     /product="BacT"
                     /protein_id="QLA09668.1"
                     /transl_table=11
                     /translation="MELTINIKNIGYQTEIIIDKVNINIKNTGLYKLEGSNGSGKSTLF
                     KALNGELDWIKNQDINVELNKKKINVFKNKEIFFINDSFEGYMFLKPVEYITFLSQLYN
                     QKIQHNYMLSIFEKLDFSKFSHHLIKDLSQGNKQKLVFITSLLINCPIILFDEAFEHID
                     KNSMNYIRNNAKELLNNKIVLLTSHTNTLNDMIKDNLYLEDKKIYY"
     gene            3861..4331
                     /gene="bacC"
     CDS             3861..4331
                     /codon_start=1
                     /gene="bacC"
                     /inference="ab initio prediction:Prodigal:002006"
                     /product="BacC"
                     /protein_id="QLA09669.1"
                     /transl_table=11
                     /translation="MISIIIGFIIGFINKSNGTLKQIIETKGFFINFYEIFIHNLWVAI
                     LIILLSFLIYIGGTFVVFSNFIIFGESLYMAMNLSYKKTISIYLHGIFEIPAIIIALFI
                     SYSISTFLIKKLKDEDFSVLNNFKKLKKHFIIMIILFIIGATIESFTLNIML"
     gene            4365..4874
                     /gene="bacD"
     CDS             4365..4874
                     /codon_start=1
                     /gene="bacD"
                     /inference="ab initio prediction:Prodigal:002006"
                     /product="BacD"
                     /protein_id="QLA09670.1"
                     /transl_table=11
                     /translation="MHLQLINNQKVIRFSFFILWLFSTFLLFINMNNKETLILEQIKGL
                     GVSPEQLNLFKIVSVVINVFFTSVLLIIVYIILRWTFKKIYNDEQTRKTMFSSIFFLNL
                     NLKFLLFIILNTLSNVFGLDNSKLTIINSILFILISVILNAKIAKIIKIDKFYILPIVF
                     LIVLVI"
     gene            4898..5092
                     /gene="bacA"
     CDS             4898..5092
                     /codon_start=1
                     /gene="bacA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:Prodigal:002006"
                     /product="BacA"
                     /protein_id="QLA09671.1"
                     /sec_met_domain="TIGR03651 (E-value: 3.3e-08, bitscore:
                     22.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFELTGIGIGSGTAATIVNWIMWGMSAATILSLISGVASGGAWI
                     LAGAREALKAGGKKAAIAW"
ORIGIN
        1 tcatttttct ttcacttcca ttccgtcata tacattgtcg gaaggatttt taaccacctt
       61 ttgccccact gttacgcctt caagaacttc tgtccagtct ccatcagtag aacctttttt
      121 cacattttgt ttacgcagtt ttcctttttc ttctacataa acaaatggtt cgccatcttt
      181 ttctacaatg ctcttactaa gaacagctat catcttctta ttttctaagc ttacttgtag
      241 cgatacgtga taacctggag ataaaccttc ttgtccatct agacttgctt tatatgtata
      301 ctgagacata ttttgtgtgc cttcacccgc gtcagctgct tgcgccatct ctgcacttgt
      361 tgggaattca cttatttctg taattttccc tgtccatttc tgcttactat ttgcttttgc
      421 agttgcaata aatgtttgat ccttttggat ttgtgatttt tgaagctcag ttaacgttcc
      481 ttgaatttgg aatggatctt tagatgcaat ttgtagaaat gattttcctt gtccgcccat
      541 cgcttgtgct gagctttgcg ctgcatcttt atctagcttt tgaacaacac cagcaaaatt
      601 actataaatc gtgagtttac cttgtttttt ctttaactct tgtgattgta attctccttt
      661 ttctttctca aggtcaattg ttttttgctg catttccaat tcatttactt gctcttccat
      721 aggatctgtt acttctttgc cagcaccact atcttttgct ttcttaatct ctttctttaa
      781 tgaatctatt ttctttttcc cttgatcata gcgcatagtt gccatttttt gatcaagcgc
      841 agcttgcttc agctgtaagt taatttcttc attatcataa gagaataatt tcgttccttt
      901 ttctacctct tgcccttctt tcaccgcaat atccttcact tttcctttag tcggatctgc
      961 gtagaagctc tcaatatttc caggttttac ttgtccagaa atcaacttcg tattgttaag
     1021 tgaacgttct gtcaccttct ggaaacttat atctgcattt ttttcactct tcgcttttcc
     1081 ttgcaccatg aaaatattcg ttgccgcaaa aaatatacat aaaagaacaa ttccaattac
     1141 aatttttttt tgtttaatta taaaacctat ttttcgaaac atttaatatc tatccccttt
     1201 tttatttata tatattctat caaagtcaat tatctcaaaa ttctcatata aaaaacacaa
     1261 aatattatta taaagaaaaa atataaaaaa tacgtttaca tagcattctc ttgaaatggt
     1321 taaatttcat ttaattttaa taatcttcta tatgaaacat atttttttcg aatctcttat
     1381 atataaataa aattcaacaa accatatatt gcactaacat gaaaaatact ttatatttaa
     1441 aatgatattt gaaatatata ccagaaagaa taggtaaagt aaaatgattc ataataaatt
     1501 attaataata aaactcacta tcttaaatca attcagacaa agtatggata taaaatccaa
     1561 ggaattaaaa aaagaatatc cctatatccc aatgaaaata atcccaatta taactctaat
     1621 tctttgtata atgggactca tagttcctct aattacgtct gtaattttag caagtttatt
     1681 aatttatacc aacgattata tatattctct atatatatac atatatatat ataacctgaa
     1741 aaatctaata aataaatttg aaatcaatag tggtaaaata aatgaacgaa tatcctttat
     1801 aaaatatagc tctaataaat atttatataa tttatttaaa atctataatc caataaattt
     1861 tattcctata ataatatttt tattgtcttt tttaatcaaa gccatattaa atcaagatat
     1921 tatatttact tttttaatta tatcttgcat tttaactatt tactttatta cgaaaagaat
     1981 tgatgtattc tttcaattat tatctctagt caatttttca tacatctcat acatattaca
     2041 tagcatatca tctgaaataa aatggaataa tatacttaaa atagattact ttattaaaga
     2101 taataaaaac attataaaat tagactggaa ccaaattttt acatattatt tttcatctat
     2161 acttttactc tcattaacat ctttattaat ttataaactt ataaacaaca taaataaaac
     2221 aaataaaaat ataaaaaagg aaaaaaagat gaagaaaaac ttatctaaag atatattagt
     2281 ttacttgaat ttttcaaact cgttaacatt aaacagaaaa ttatctttat ggataccatt
     2341 aggaccaatg atgattatat ctataccttt atttataaat atcccatctc aaaaatattt
     2401 atttataatc tttatgggaa ttatagtatg tctttataca aaacgtttta tgtatcaata
     2461 cacatatttt ttccattatt ttacaaacaa aaaagaaaaa caacttttta aactcaattt
     2521 taaaaaccta tttaacattc taaaaacaaa attattgata ttacttataa accaattaac
     2581 acttattata tatatatatg gcttatacat aacaatattt tggaacaaca ttcaatttac
     2641 cgatttatta attttaacat ttgtatacat tgtttcttta acaataccat tatccgaaaa
     2701 gaaatttatt atttttgact ttcaaacatt aaagttaaat aaagataacg attatggtgg
     2761 cacaatggaa gttctatact caatgtgttt aataatttta ttttttgtaa acctaggatt
     2821 ggaagtcaat aatatcaaat ttgacatatc atttttaaca attttattac catttttatt
     2881 cttaattttt tctgtaacaa aagtatattt aaatatcaaa atttggggga tacatcatga
     2941 aaataattaa ttatctattc ttagctatac tattcatatt tcaaattcat caaattttaa
     3001 aacatagata tgcttataaa aatactcaaa aaaaatatca taaaaacatg gtaattgtct
     3061 tttctattat tttagtttta acatcaatat caataatagc tacatattta aatatttaaa
     3121 atcctacaac ataaaagtaa agaaaaaggg agaacttaaa atggaattaa ccattaatat
     3181 aaaaaatata ggataccaaa cagaaataat aatagacaaa gtcaatataa acataaaaaa
     3241 tactggtcta tataaattag aaggtagtaa tggatcagga aaatcaactc tttttaaagc
     3301 tttaaatggt gaattagatt ggattaaaaa ccaagatata aatgtagaat taaataaaaa
     3361 aaaaataaat gtctttaaaa acaaagaaat attctttata aatgatagtt ttgaaggtta
     3421 tatgttttta aaaccggtag aatatataac ttttttatcc caattatata atcaaaaaat
     3481 ccaacataat tacatgttga gtatatttga aaaattggac ttttctaaat tctcgcatca
     3541 tttaatcaaa gatttatcac aaggaaacaa acaaaagcta gtattcatca catcattatt
     3601 aataaattgt cctattatac tatttgatga agctttcgaa catattgaca aaaatagcat
     3661 gaattatata aggaacaatg ctaaagaact actaaataat aaaatcgtat tactaacttc
     3721 tcacacaaac acattaaatg acatgataaa agataaccta tacctagaag acaaaaaaat
     3781 atactattaa cttatctata aaccataaaa aagggtgaat caacataaaa acaattaaat
     3841 atgcttctat attaataagt gtgatatcta taataattgg ctttattata ggttttatca
     3901 ataaaagtaa tggaacattg aaacaaatta tagaaaccaa aggtttcttt ataaattttt
     3961 atgaaatatt tatacataat ctttgggtag ctatcttgat tatactctta agtttcttaa
     4021 tatatattgg aggaactttt gtagtttttt caaatttcat aatttttgga gaaagtttat
     4081 atatggctat gaacttatct tataaaaaaa caattagtat atatctacat ggaatatttg
     4141 aaataccagc tataattatt gccctattta tttcatattc aatttcaacc ttcttgataa
     4201 aaaaactaaa agatgaagat ttttcagttc ttaataattt taaaaagtta aaaaaacatt
     4261 ttattataat gattattcta ttcataatag gagcaacaat agaatcattt acacttaata
     4321 taatgctata aaaaatatca ttatttataa aaggagagaa ttaaatgcat ctacagttaa
     4381 taaacaatca aaaagttatt agattttcat tttttatatt atggcttttc agtacctttt
     4441 tattatttat aaatatgaat aacaaagaaa ctcttatttt agaacaaata aaaggtttag
     4501 gtgtttctcc agaacaactt aatttattca aaatagtatc agttgttata aatgtatttt
     4561 tcacatcagt attattaatt atagtttata taatactccg ttggacattc aaaaaaatat
     4621 ataatgatga acaaactaga aaaacaatgt tttcaagtat atttttcctt aatttaaatc
     4681 taaaattttt gttattcatt atattaaaca cactatcaaa tgtattcgga cttgataatt
     4741 ctaaattaac aataattaat agtattcttt ttatattaat atctgtaatt ttaaacgcaa
     4801 aaatagcaaa aattataaaa atagacaaat tttacatttt acctattgtt tttttaatcg
     4861 tcttagttat ataatacgat tataggaggt gagaaatatg ttattcgaat taactggtat
     4921 tggtattggc tctggtacag ctgcaactat tgtaaactgg attatgtggg gaatgagtgc
     4981 tgctactatt cttagcttaa ttagtggagt tgcaagtggt ggagcatgga tccttgcagg
     5041 tgctagagaa gctcttaaag caggcggtaa aaaagctgct attgcttggt aa
//
