BGC0002525 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002525 (Fusarium sp)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	24,500	fusarubin/1233A/1233B/NG-391/lucilactaene	PKS	100%

BGC0002525 - Region 1 - T1PKS

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Location: 1 - 24,500 nt. (total: 24,500 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,501
Label		BGC0002525

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002525	1.00	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0001924	0.34	Terpene	ascofuranone	Acremonium egyptiacum
BGC0002191	0.32	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002155	0.29	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0001252	0.28	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002194	0.27	Polyketide	epipyrone A	Epicoccum nigrum
BGC0000146	0.26	Polyketide	solanapyrone D	Alternaria solani
BGC0002515	0.26	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0001899	0.25	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0002173	0.25	Terpene, Saccharide	fumihopaside A, compound 3, 21-β-H-hopane-3beta, 22-diol	Aspergillus fumigatus A1163

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002525	1.00	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0001924	0.67	Terpene	ascofuranone	Acremonium egyptiacum
BGC0002191	0.66	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002155	0.63	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0001252	0.62	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002194	0.60	Polyketide	epipyrone A	Epicoccum nigrum
BGC0000146	0.60	Polyketide	solanapyrone D	Alternaria solani
BGC0002515	0.60	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0001899	0.59	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0002173	0.58	Terpene, Saccharide	fumihopaside A, compound 3, 21-β-H-hopane-3beta, 22-diol	Aspergillus fumigatus A1163

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 24500:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

g433

PKS_AT (574..877): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 66.7%; Isobutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 81.1
Methoxymalonyl-CoA: 71.7
Isobutyryl-CoA: 56.5
Propionyl-CoA: 53.2
Malonyl-CoA: 52.3
Ethylmalonyl-CoA: 51.8
trans-1,2-CPDA: 33.8
2-Methylbutyryl-CoA: 27.9
Benzoyl-CoA: 24.4
CHC-CoA: 15.0
fatty_acid: 13.1
Acetyl-CoA: 0.1
inactive: 0.0
3-Methylbutyryl-CoA: 0.0