LOCUS       BGC0002529             15584 bp    DNA     linear   BCT 11-DEC-2013
DEFINITION  Azotobacter vinelandii CA, complete genome.
ACCESSION   BGC0002529
VERSION     BGC0002529
KEYWORDS    .
SOURCE      Azotobacter vinelandii CA
  ORGANISM  Azotobacter vinelandii CA
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Azotobacter.
COMMENT     Source bacteria available from the submitter.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 17:55:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15584
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15584
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3772:12829]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3773..12829
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..15584
                     /SMILES="NC([*])C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15584
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002529"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15584
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1653
                     /locus_tag="AvCA_09640"
     CDS             1..1653
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 182.7; E-value: 2e-55)"
                     /gene_kind="transport"
                     /locus_tag="AvCA_09640"
                     /product="ABC transporter, transmembrane region, ATP
                     binding component"
                     /protein_id="AGK15450.1"
                     /transl_table=11
                     /translation="MLAIILVFLTLLGAFCNVGFGLLIKATIDTLSSASKDLNTLIIFS
                     VLFVSIRFLTPMVHGAKEFVCSKLSDEEEAHLRHQAFRTLHNFDHDYQVAKNTGDVIRR
                     VQVGLSAFKSITRALFLNVMPVALDVLLIIGIVTYFFGLGYAAVIASVVAAYLSIVFYF
                     TNRRMSFLAEVSDTDRALAAFTHDSYLNQESVRLFIPIQDELNQHWQFIDRYLSAQQKS
                     RRNLYWLTTLTSVVSALGCLLILIWGSLSITHQMMTIGGYLMLTAYLFQIFLPLNSLGL
                     SFRQIKKGLYDMTQMKDILDLASVESERNIDLHIRPGAPILLRFEDLSLQSRDGSEIFT
                     KLQGTLHLNGLAFVVGKSGIGKSSIVRMLCGLTKPSFGRLTINGYDCQHLSQESIRANM
                     AIASQDVVLFNSTLKQNLLVANPNATDDELLIVLNKVGLGYLFDDQRGGLDCQVGERGQ
                     KMSGGEKQRISLARALLKSAPLIILDEPTAALDSENTKNIRLLIDAVAQNACLLVITHD
                     TSLIKEESDNVYELSTVGLKPIGVSTCPRSTVE"
     gene            2841..3569
                     /locus_tag="AvCA_09670"
     CDS             2841..3569
                     /codon_start=1
                     /locus_tag="AvCA_09670"
                     /product="thioredoxin-like fold protein"
                     /protein_id="AGK15449.1"
                     /transl_table=11
                     /translation="MAGFRQWKYGCWLMAIGKFKVLHTIVCQKMNGEKLLFCCFIAFLA
                     LVGNGVNANEYVEGRHYKTLSADIEGYQDKVVEFYNFACVYCFRAEGGVAYLEQHLPEN
                     IQLTRLPLVLGKGERFNSAAYVGWIADELGYMEKYRHYLFQLARAPLPWEIKRYNRLSS
                     MENVRTLFMDMGTDAKIYEAAVKSAKARIEITEALARQLKITSTPAFLVRGKYLVQGMR
                     SKPFAEFMMADLILHLAIKP"
     gene            3773..7651
                     /locus_tag="AvCA_09680"
     CDS             3773..7651
                     /NRPS_PKS="Domain: Condensation_Starter (5-292). E-value:
                     8.5e-56. Score: 181.3. Matches aSDomain:
                     nrpspksdomains_AvCA_09680_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (446-847). E-value: 5.5e-71.
                     Score: 231.1. Matches aSDomain:
                     nrpspksdomains_AvCA_09680_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (956-1020). E-value: 3.9e-14. Score:
                     44.5. Matches aSDomain: nrpspksdomains_AvCA_09680_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     178.8; E-value: 3.5e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AvCA_09680"
                     /product="AMP-dependent synthetase and ligase family
                     protein"
                     /protein_id="AGK15448.1"
                     /sec_met_domain="Condensation (E-value: 2.7e-30, bitscore:
                     93.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.3e-74, bitscore:
                     237.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-14, bitscore:
                     41.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGMLERSYRLLAAQEGFYYGHELRDNKADFNVAEYVVIEGEFDVD
                     RFYQANKSVLADIETLSFVFRSHDGHGRQQHLPRPVKLELVDLRGLSTGFEIALSQMTV
                     DSAKPFDITNDVLYRQCLYRISDSCQLWYFCSHHLVLDAFAMLQVLSRVAKAYRSVGAV
                     VIDRTASNFSAVVSAEDAYLESATYALNYDYWQHQVSLLPEPTSLSPKPQHAGECLRFS
                     CEEPVPTGWFGLMAEKVDWPSRLITSLLVYLWMMSGNRRQVIGIPMLARKAPAEWAVPA
                     CRVNVLPLSVELCAEASVEQTLAAVSDRLSQLKRHQQYPAGALSSGLQSLPFNTVLNIL
                     PFTPHVMFDIQQESEVRNIRAGAVNDIAFTVRPDLAGSRLHVTVDANGRLYSASDLQMH
                     VSGLLNVVRTLMAQPQIHLSALPRPRPMAWLEGARACARQDVLSSIFDRAQNQGKQVAL
                     TDICNPQENWQSITYQVLVDEVERLAHSLRECAAFDLLVLDLPRSSDSILFMLIALRLG
                     VPFVVLNPMRAQQMLEVLVQHATHALLVARQEVSSDSAGWQESAQYLQIKGYEALRFTR
                     LQGEGTSGFGALAYLMFTSGTAGKAKAVKISRQAMDAFVGTAVNRYGFDTTDVVLNFSE
                     HFFDACIEEIFGALTAGARLVIRPADAHRSTRHFLSFCAMQAITVLDLPTAYWHEMAIA
                     MDAHMMKRTRVRLVVIGGERVSEQALYHWFEKVGDSPQLFNSYGPTEATVVATCALLDK
                     AEGASIGRPLAGVQCAILGPGLTLLPQGASGELLLFGDTLAEGYLGDAERTTERFVEIC
                     IDGKMRRGYRTGDLALLGRDNQLHYMGRLDHEVKIAGQRLNLSELEALIEACAGVREVC
                     VVLQESIFPRSLSAHIYGDPALEQTVRRDLGSQIAPEFLPRSYHWHASPLPKTFSGKID
                     RAQLQRHGKKTPPLSLPKIVERQGWLEQHVRMIWCESLGSNEALDFFQQGGDSLMALRM
                     VNRLNAELGLALTMETVFDSKTLKGLLAYIVREITKLGLQVDCLELRNALLKPPSPVQW
                     SARRTVFLEAHPLHHFADLQGLAEKLDLYLVVSRNDDAQPVGKDCSVQDRLYWHDVQGG
                     LWHQGQAWPVTQIPAVQYAIFIMPHRPEAYPAWSQRCLERLRQLQMHNLERALIVTDRE
                     GRRWFEKHILSAAECKRLEFHTCSPHALQERQHQEELIVDWSVRIGYFPDLNLPPCFVS
                     MRNLLAELAGRPGRVRMSVRDRLFARAQSFNPDVKVCSFAQWLKEITRYSGSPCHRLEQ
                     RTVYRLNL"
     aSDomain        3788..4648
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09680_Condensation_Starter.
                     1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="8.50E-56"
                     /label="AvCA_09680_Condensation_Starter.1"
                     /locus_tag="AvCA_09680"
                     /protein_end="292"
                     /protein_start="5"
                     /score="181.3"
                     /tool="antismash"
                     /translation="RSYRLLAAQEGFYYGHELRDNKADFNVAEYVVIEGEFDVDRFYQA
                     NKSVLADIETLSFVFRSHDGHGRQQHLPRPVKLELVDLRGLSTGFEIALSQMTVDSAKP
                     FDITNDVLYRQCLYRISDSCQLWYFCSHHLVLDAFAMLQVLSRVAKAYRSVGAVVIDRT
                     ASNFSAVVSAEDAYLESATYALNYDYWQHQVSLLPEPTSLSPKPQHAGECLRFSCEEPV
                     PTGWFGLMAEKVDWPSRLITSLLVYLWMMSGNRRQVIGIPMLARKAPAEWAVPACRVNV
                     LPLSVE"
     aSModule        3788..6832
                     /complete
                     /domains="nrpspksdomains_AvCA_09680_Condensation_Starter.1"
                     /domains="nrpspksdomains_AvCA_09680_AMP-binding.1"
                     /domains="nrpspksdomains_AvCA_09680_PCP.1"
                     /locus_tags="AvCA_09680"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3857..3970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0001"
                     /evalue="4.90E-11"
                     /label="C2_starter_024-063"
                     /locus_tag="AvCA_09680"
                     /protein_end="66"
                     /protein_start="28"
                     /score="35.2"
                     /tool="antismash"
                     /translation="DFNVAEYVVIEGEFDVDRFYQANKSVLADIETLSFVFR"
     CDS_motif       4181..4243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0002"
                     /evalue="2.90E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="AvCA_09680"
                     /protein_end="157"
                     /protein_start="136"
                     /score="23.4"
                     /tool="antismash"
                     /translation="HHLVLDAFAMLQVLSRVAKAY"
     CDS_motif       4556..4639
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0003"
                     /evalue="1.50E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="AvCA_09680"
                     /protein_end="289"
                     /protein_start="261"
                     /score="27.1"
                     /tool="antismash"
                     /translation="QVIGIPMLARKAPAEWAVPACRVNVLPL"
     CDS_motif       4691..4789
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0004"
                     /evalue="2.70E-06"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="AvCA_09680"
                     /protein_end="339"
                     /protein_start="306"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SDRLSQLKRHQQYPAGALSSGLQSLPFNTVLNI"
     aSDomain        5111..6313
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09680_AMP-binding.1"
                     /evalue="5.50E-71"
                     /label="AvCA_09680_AMP-binding.1"
                     /locus_tag="AvCA_09680"
                     /protein_end="847"
                     /protein_start="446"
                     /score="231.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRAQNQGKQVALTDICNPQENWQSITYQVLVDEVERLAHSLRECA
                     AFDLLVLDLPRSSDSILFMLIALRLGVPFVVLNPMRAQQMLEVLVQHATHALLVARQEV
                     SSDSAGWQESAQYLQIKGYEALRFTRLQGEGTSGFGALAYLMFTSGTAGKAKAVKISRQ
                     AMDAFVGTAVNRYGFDTTDVVLNFSEHFFDACIEEIFGALTAGARLVIRPADAHRSTRH
                     FLSFCAMQAITVLDLPTAYWHEMAIAMDAHMMKRTRVRLVVIGGERVSEQALYHWFEKV
                     GDSPQLFNSYGPTEATVVATCALLDKAEGASIGRPLAGVQCAILGPGLTLLPQGASGEL
                     LLFGDTLAEGYLGDAERTTERFVEICIDGKMRRGYRTGDLALLGRDNQLHYMGRLDHEV
                     KI"
     CDS_motif       5537..5593
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0005"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="AvCA_09680"
                     /protein_end="607"
                     /protein_start="588"
                     /score="14.7"
                     /tool="antismash"
                     /translation="AYLMFTSGTAGKAKAVKIS"
     CDS_motif       6107..6196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0006"
                     /evalue="2.50E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="AvCA_09680"
                     /protein_end="808"
                     /protein_start="778"
                     /score="32.6"
                     /tool="antismash"
                     /translation="PQGASGELLLFGDTLAEGYLGDAERTTERF"
     CDS_motif       6281..6346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09680_0007"
                     /evalue="1.90E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="AvCA_09680"
                     /protein_end="858"
                     /protein_start="836"
                     /score="20.4"
                     /tool="antismash"
                     /translation="YMGRLDHEVKIAGQRLNLSELE"
     aSDomain        6641..6832
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09680_PCP.1"
                     /evalue="3.90E-14"
                     /label="AvCA_09680_PCP.1"
                     /locus_tag="AvCA_09680"
                     /protein_end="1020"
                     /protein_start="956"
                     /score="44.5"
                     /tool="antismash"
                     /translation="EQHVRMIWCESLGSNEALDFFQQGGDSLMALRMVNRLNAELGLAL
                     TMETVFDSKTLKGLLAYIV"
     gene            8663..12829
                     /locus_tag="AvCA_09690"
     CDS             8663..12829
                     /NRPS_PKS="Domain: Condensation_LCL (76-365). E-value:
                     6e-58. Score: 188.1. Matches aSDomain:
                     nrpspksdomains_AvCA_09690_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (533-925). E-value: 5e-85.
                     Score: 277.4. Matches aSDomain:
                     nrpspksdomains_AvCA_09690_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1037-1102). E-value:
                     4.6e-10. Score: 31.8. Matches aSDomain:
                     nrpspksdomains_AvCA_09690_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     238.3; E-value: 3.1e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AvCA_09690"
                     /product="Non-ribosomal peptide synthetase, with
                     condensation, AMP binding and thioesterase modules"
                     /protein_id="AGK15447.1"
                     /sec_met_domain="Condensation (E-value: 2e-51, bitscore:
                     163.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-94, bitscore:
                     303.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-11, bitscore:
                     31.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGLSALIELAEKGWAFERVSAERLDICRSTNNEGEALWQHSKAQ
                     IFEFLSDTEKSQDERTGIRSVRPGETFVVNRYAGQYLWVFDNLRHHSALYNIPLCKRIS
                     GSVDVERLIYALSRLVQHHGIFATVYQLQEAQLHMSTRVLPTSLFADALTDISGLSTSQ
                     QQQWLENFTLECSQCAFDLSCEVPIRCRIVRTRDDEHWLFLTFHHSAVDGWSIGQFLNE
                     LSATYQDLSFVPDCLPAAWSYAQNPFAFIASVDESLAFWMKELEHAPARHGLAYDAVEK
                     HTDLHKNVVTSILSEASLQSLKGFSRAHGVSISVVLQATFVLLLSKLSRQRRIVIGTPV
                     ANRPHVELNTALGSFVNTIALYFNLEEVQSFSDLVQVAQDKLIRSHPHHGLPFSYVVEQ
                     LRPERGDFNPIYQILFVCQHQQDSHLQFVDAQVHDVQRTYSTPKSDLALEVILHQDRIT
                     LEWQFHPNYFSFDRIASFAQHFLNLLEQVMKAPSLPLGCFGLMSPKRRKTLLELSMGDQ
                     VDVFVGQTLDRLMEQSKSRFADNIAVIDGNDQYTYAQLFAGAKSLAGYLDSLCEPQAIV
                     AVQIKRGYLQALLLLATVLSGRVYLPLAMDTPISRARSILESSGCTLLIGDVLDEQMYP
                     GIRVLPSRILWCQLEHAPFTRDTSISPSDLAYLIYTSGTTGTPKGVAIEHAAVCNTLLA
                     MNQYFGVSQHDRVLAISNISFDLSVYDLFGTWTAGACVVLLSESASKDPASWVQAIHAN
                     HVSVWNSVPMVLQMMLAFVQGLRLNTFPGVRHIWLSGDWIPPKLIEQARCCFPQAKIIS
                     LGGATEGSIWSIYHPLQDQVYLGSIPYGRALPNQGMFVLDEQLELCDFGVSGDIYIAGY
                     GVARGYHQAPRLTESKFTVHPQLKQRLYKTGDRGRWHTAGYIEFLGREDKQVKIQGYRV
                     ELGEVESVLKRASFVRDAVVLIRSSTGGGGSYLEAHIVASPLTAQLEPTLRAHAALLLS
                     PYMQPLHYGFYEQFPLSANGKVDTSRLRRLAPMRASSTSGWDADEHLFKLMEIVSVVLD
                     RPMAELDPQHSFYQLGGTSLQAVSLAVKGATHWQVNLSITDILEASSLVELAEKIRVVP
                     LVLSKLSTFEQASVGALSLCFVHAAGGHLEPYRTLQTRYAGRCNLFGLSSPALASIGPD
                     CELAFEALLEAHVNSLLDIPSQGHLVLVGWSLGGILAMNLCERLVRHGIRVRHVVVVDS
                     GLDYAPMVGKGRTKQWLRLVANAVEMYGLDKHCLIVKGAEGFSSFAGLLKYLYTVNEEK
                     LSAVLSRSQFEVSAWALERACRLLAEASIPKLDTALSVHLCQTHQTIASSQILRWQDLS
                     PKVDIIELAAEHNSILSVPSFLRSLDSLLESLQVSEGKAIDTANG"
     aSDomain        8891..9757
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09690_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.00E-58"
                     /label="AvCA_09690_Condensation_LCL.1"
                     /locus_tag="AvCA_09690"
                     /protein_end="365"
                     /protein_start="76"
                     /score="188.1"
                     /tool="antismash"
                     /translation="YAGQYLWVFDNLRHHSALYNIPLCKRISGSVDVERLIYALSRLVQ
                     HHGIFATVYQLQEAQLHMSTRVLPTSLFADALTDISGLSTSQQQQWLENFTLECSQCAF
                     DLSCEVPIRCRIVRTRDDEHWLFLTFHHSAVDGWSIGQFLNELSATYQDLSFVPDCLPA
                     AWSYAQNPFAFIASVDESLAFWMKELEHAPARHGLAYDAVEKHTDLHKNVVTSILSEAS
                     LQSLKGFSRAHGVSISVVLQATFVLLLSKLSRQRRIVIGTPVANRPHVELNTALGSFVN
                     TIALYFNL"
     aSModule        8891..11968
                     /complete
                     /domains="nrpspksdomains_AvCA_09690_Condensation_LCL.1"
                     /domains="nrpspksdomains_AvCA_09690_AMP-binding.1"
                     /domains="nrpspksdomains_AvCA_09690_PP-binding.1"
                     /locus_tags="AvCA_09690"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8939..9052
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0001"
                     /evalue="9.40E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="AvCA_09690"
                     /protein_end="130"
                     /protein_start="92"
                     /score="24.5"
                     /tool="antismash"
                     /translation="ALYNIPLCKRISGSVDVERLIYALSRLVQHHGIFATVY"
     CDS_motif       9278..9343
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0002"
                     /evalue="7.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="AvCA_09690"
                     /protein_end="227"
                     /protein_start="205"
                     /score="28.1"
                     /tool="antismash"
                     /translation="FHHSAVDGWSIGQFLNELSATY"
     CDS_motif       9662..9745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0003"
                     /evalue="3.80E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="AvCA_09690"
                     /protein_end="361"
                     /protein_start="333"
                     /score="35.4"
                     /tool="antismash"
                     /translation="IVIGTPVANRPHVELNTALGSFVNTIAL"
     CDS_motif       9818..9910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0004"
                     /evalue="9.20E-09"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="AvCA_09690"
                     /protein_end="416"
                     /protein_start="385"
                     /score="27.6"
                     /tool="antismash"
                     /translation="HPHHGLPFSYVVEQLRPERGDFNPIYQILFV"
     aSDomain        10262..11437
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09690_AMP-binding.1"
                     /evalue="5.00E-85"
                     /label="AvCA_09690_AMP-binding.1"
                     /locus_tag="AvCA_09690"
                     /protein_end="925"
                     /protein_start="533"
                     /score="277.4"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="KSRFADNIAVIDGNDQYTYAQLFAGAKSLAGYLDSLCEPQAIVAV
                     QIKRGYLQALLLLATVLSGRVYLPLAMDTPISRARSILESSGCTLLIGDVLDEQMYPGI
                     RVLPSRILWCQLEHAPFTRDTSISPSDLAYLIYTSGTTGTPKGVAIEHAAVCNTLLAMN
                     QYFGVSQHDRVLAISNISFDLSVYDLFGTWTAGACVVLLSESASKDPASWVQAIHANHV
                     SVWNSVPMVLQMMLAFVQGLRLNTFPGVRHIWLSGDWIPPKLIEQARCCFPQAKIISLG
                     GATEGSIWSIYHPLQDQVYLGSIPYGRALPNQGMFVLDEQLELCDFGVSGDIYIAGYGV
                     ARGYHQAPRLTESKFTVHPQLKQRLYKTGDRGRWHTAGYIEFLGREDKQVKI"
     CDS_motif       10658..10717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0005"
                     /evalue="3.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="AvCA_09690"
                     /protein_end="685"
                     /protein_start="665"
                     /score="31.8"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGTPKGVAIEH"
     CDS_motif       11243..11326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0006"
                     /evalue="3.90E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="AvCA_09690"
                     /protein_end="888"
                     /protein_start="860"
                     /score="32.0"
                     /tool="antismash"
                     /translation="GVSGDIYIAGYGVARGYHQAPRLTESKF"
     CDS_motif       11405..11470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0007"
                     /evalue="4.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="AvCA_09690"
                     /protein_end="936"
                     /protein_start="914"
                     /score="31.6"
                     /tool="antismash"
                     /translation="FLGREDKQVKIQGYRVELGEVE"
     aSDomain        11774..11968
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AvCA_09690_PP-binding.1"
                     /evalue="4.60E-10"
                     /label="AvCA_09690_PP-binding.1"
                     /locus_tag="AvCA_09690"
                     /protein_end="1102"
                     /protein_start="1037"
                     /score="31.8"
                     /tool="antismash"
                     /translation="KLMEIVSVVLDRPMAELDPQHSFYQLGGTSLQAVSLAVKGATHWQ
                     VNLSITDILEASSLVELAEK"
     CDS_motif       12224..12292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AvCA_09690_0008"
                     /evalue="9.70E-08"
                     /label="NRPS-te1"
                     /locus_tag="AvCA_09690"
                     /protein_end="1210"
                     /protein_start="1187"
                     /score="24.5"
                     /tool="antismash"
                     /translation="QGHLVLVGWSLGGILAMNLCERL"
     gene            13752..15584
                     /locus_tag="AvCA_09700"
     CDS             13752..15584
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     252.4; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AvCA_09700"
                     /product="lantibiotic modifying enzyme"
                     /protein_id="AGK15446.1"
                     /transl_table=11
                     /translation="MFSTKSKARHLGGGAPIKRETEVIYATAINGGDCVTAANYNGKHR
                     VLVEVIINDILERTCFDKRKDIHRKLVTALAGYAANKIDLYMRHVLEFELGSLSEVLEN
                     VNLDYIMDSDELYIAILKKYPGLEPLVDHLGSSLIENFTLIIKSFEDAEFELVSNGYLS
                     SVNNITNIFLLSDESHDANKNIVLFYDSYKPAFALKLRNITLEKQTNDFISGFLRENMG
                     FEDWNFPNYLDHGEVGWVSWRPRQDLNSEKQITESYFRSGVLASISCALGITDLNHENI
                     IIHAGSPVIVDLETTLHHCVEGGGSTNALRTGLFPSFLKLDRNGSPTEESCGIGNIFPE
                     YRLKSKNNEVCFDNKIASPIDYIEYIKQGLRLGFAKVIQYKEKFVDHIVRIENFRTRFI
                     FKATYSYATIIESSMHPALLKSAVIREEYITQCFESENKYVEGDEAKWGEIKACYLGDV
                     PRFITTANSLILDSYYQQTPTTLRHICTGVSRTLQYLQDLNDKIVDEEIFYIEKSYAEA
                     YRVMSVNAKSYEIENYQKLINCANEFALNNKMPVFFMPRNDYCLELKSCGLDIFSGIGG
                     IVYLAAIKKLPVESTISDRIIANYIERLNSTQRN"
ORIGIN
        1 atgctagcaa taattttggt atttcttacg cttttgggcg ctttttgcaa tgttggcttt
       61 ggtttgttaa taaaagccac gattgatacg ctaagcagcg cttcaaaaga cttgaatacg
      121 cttatcattt tttcagtttt attcgtgtcg atccgctttc ttactccgat ggtacatggg
      181 gctaaggagt tcgtttgctc taaattgtct gatgaagaag aagcgcatct gcgacaccaa
      241 gccttcagaa cattgcataa ttttgatcac gattatcagg ttgcgaaaaa taccggtgat
      301 gttattcgtc gtgtccaagt tggtctgagt gctttcaagt ccataactcg tgcgttattt
      361 cttaatgtta tgcctgtagc gctggatgtt ctattgatca tcggcattgt cacctacttc
      421 tttggtctag ggtatgcagc agtaatcgct agtgttgtcg ccgcgtactt gagtatagtg
      481 ttctacttta ctaaccgtcg tatgtcattc ctcgcagagg tatctgatac agatagggca
      541 ctagcagctt ttactcatga cagctattta aaccaggaaa gcgtcaggct atttattccg
      601 attcaggatg agctgaatca acactggcaa tttattgata gatacttgag tgcccagcaa
      661 aaatctaggc gtaatttata ttggctgact accttgacgt cagtggtctc cgctttgggc
      721 tgcttattaa ttctgatatg gggtagcctg agcattactc accagatgat gaccatcggt
      781 ggttatctga tgcttaccgc ttacttgttt caaatctttc tacctttgaa ttcgctgggt
      841 ttgtcattta ggcagatcaa gaaaggtctg tatgatatga cacaaatgaa agatattctt
      901 gatcttgcgt cagtcgagtc ggagcgcaat atcgatctgc atattagacc aggggcacca
      961 atactattgc gttttgaaga tttatctttg cagtcacgcg acggcagcga gatatttact
     1021 aagcttcaag gtacattgca tcttaatggg cttgcatttg ttgtagggaa aagtggtatt
     1081 ggcaagtctt ctatagtaag gatgctatgc ggtctcacca agcctagttt tggtcgttta
     1141 actattaatg gttatgattg tcagcattta agtcaggagt ctattcgtgc aaatatggct
     1201 atcgccagcc aggatgttgt actgttcaat tctactctga agcaaaatct cttggtggcc
     1261 aatccaaatg ccactgatga tgagttgctg atagtattaa ataaagtcgg tctcggctat
     1321 ctatttgatg atcaacgcgg tggacttgat tgtcaggtag gagagcgcgg gcagaaaatg
     1381 tctggtggtg aaaagcagcg tatcagctta gctcgtgcgc tcttgaagag tgctccgcta
     1441 attatccttg acgagccaac cgcggcgctt gattcggaaa atactaaaaa tattaggttg
     1501 cttattgacg cagttgctca gaatgcatgt ctgttagtga ttacccatga cacttcgctc
     1561 attaaggagg aaagcgataa tgtatacgaa ctttcgactg ttgggctcaa acccattgga
     1621 gtcagcacat gtccccgatc cactgttgag taagcacgtt tctgaattgt ttgcagatag
     1681 ccatatacgt gatcaaattg gaaaaggtat tattcatttc tcaaacaacc ccttagatac
     1741 atcagagctt ctgacttggg aagcgctcaa tacacttctt agtagtgatc ttattgacca
     1801 tcctcgattg agagtaattg ctaaaaaaaa tctttatagt cgaggttatg ctggttttat
     1861 gggctatgga gtcactgaaa ccggtgatct tattccaagc attcgcccta aacgactgtt
     1921 gcaagcactg aacgacggtt gtaccctcgt tcttgatcgc tgtcatagtt attttcattc
     1981 catcgagacg attcgtcgtt cgctaagcta tatttttgat tgtcgtactt ccgccaacct
     2041 atacgcttca tggacagaag aaccaggctt tggactgcat tacgatgacc acgacgtcgt
     2101 tgctctacaa gtcagtggtt caaagttctg gacctttcac gctccgaccc tgacagatcc
     2161 gttacctgga cagaaaagct ttaaatacga tgcaccaacg acaccgccga taaaagaggt
     2221 aatgttacga cctggggagc tggtctatgt accacgtggc tattggcacg atgtgaaaac
     2281 tatggatgca ccttccttgc atgtttcttt tgctatacca cgactgcggt accatgacat
     2341 agcaaagatt atgctggata ccctgctcaa caagcccgag tttaggcaat ctcttccatt
     2401 ggaagaagaa aatcagatgt tggatgttat acaaactgaa attctcaaat tattcagtac
     2461 taatgatttt gcggcttggg caaaggccct acggtgcttc gctatcgccg atcaacccaa
     2521 agttaatttg ccaaaactaa cattattaga atgaatcatg gatgatctta aaaaaaatcg
     2581 cattgcttgg cagaacgctt atatcgcagc cgacactgaa aaattgcaat atatggaaac
     2641 agaggatttt tccgtcaccg ttggagggaa aaccatactg cgtaaagagc gctttcaacg
     2701 tatgcgcggc gctaatttta gcgatcgctg gagttcacgg agtactcggt ttgtagatta
     2761 cgatttaatg ctggagcgtc gctcgggtag tcttgttgta attaatgcca actctgcggt
     2821 gttcgaggga gataaattaa ttggccggat tcaggcagtg gaaatatggg tgttggttga
     2881 tggcaattgg aaagttcaaa gtcttgcata cgatagtttg ccagaaaatg aatggtgaga
     2941 agttgttatt ttgttgtttt attgcttttt tggcgcttgt cggaaatggt gttaatgcta
     3001 atgagtatgt ggagggacgg cattacaaaa ctttgtcagc agatattgaa ggctatcaag
     3061 ataaagttgt agagttttat aattttgctt gtgtttattg ttttcgagcg gaaggcggtg
     3121 ttgcgtatct tgaacagcat ctacctgaga acatccaatt aacccgtttg ccattggttt
     3181 taggcaaggg cgagcgtttt aactctgcag cctatgtggg ttggatcgct gatgagctag
     3241 gctatatgga aaagtatcgt cactacttgt tccaactggc tcgagcgccg ctcccgtggg
     3301 aaatcaagcg ttataatcga ctttcaagta tggaaaacgt gcgtacgctg tttatggata
     3361 tgggtacaga tgcaaaaata tacgaagcag cagttaagag tgccaaagct cgcatcgaaa
     3421 taacagaagc attagctcga cagctcaaga ttacttcaac tcctgccttt ctagttcgag
     3481 ggaagtatct ggtacagggt atgcgctcta agccgtttgc cgaattcatg atggcggatc
     3541 tgattttaca tcttgcgata aagccatgaa aattaggctc cggaatacag catggattat
     3601 gctctgctta actgttgctg ctatggcata catcctgtaa ttctacagga agtgttacat
     3661 ttgaaatcat gctcttagtg catagcctag ggagtaatgt tcattgctga tggctatctt
     3721 gtgttgttga gtgctttgat ttttgattta tggaagtcaa ttttgcaagg atatgggcat
     3781 gctcgaaagg agctatcggc tgctggccgc acaggagggt ttttattatg gtcatgagtt
     3841 gcgtgataat aaagctgatt tcaatgtggc tgaatatgtt gttattgaag gcgagtttga
     3901 tgttgatcgg ttctatcaag ccaataaaag cgtgctggca gatatagaga cgttgagctt
     3961 tgtttttcgc tctcatgatg gccatggtag gcagcaacac ttgccgcgtc cagttaagct
     4021 cgagttggtt gacctgcgtg gtctctcaac aggtttcgag attgctttga gccaaatgac
     4081 ggtggactca gctaagccct tcgatatcac taacgatgtt ttgtaccgtc aatgcctgta
     4141 caggatcagc gacagctgtc aactctggta cttctgcagt caccatctcg tacttgacgc
     4201 ttttgccatg cttcaggtct taagtcgggt ggccaaagct tatcgctctg taggagcagt
     4261 agtaatcgac cggacagcct cgaatttttc tgccgtcgta tctgcagaag atgcctatct
     4321 ggaatcagcc acttatgctc tcaactatga ttattggcaa caccaagtgt ccttgctgcc
     4381 ggaaccaaca agcctcagcc cgaagccaca acatgcagga gagtgcctgc gtttctcctg
     4441 tgaagagcct gtgccgacgg ggtggtttgg cctcatggcg gagaaggtag attggccaag
     4501 tcgattgata acgagcttgc tggtctatct gtggatgatg agcggaaatc gtaggcaggt
     4561 tattggtatc cccatgctag cccggaaagc gccagccgaa tgggcggtcc ccgcttgccg
     4621 cgtgaatgtc ttgccactgt ccgtcgagct ttgcgctgag gccagcgtcg agcagaccct
     4681 ggcagctgtc agtgaccgcc tctcgcaact caagcgtcac cagcagtatc ccgctggagc
     4741 gctgtccagt ggcctgcaat ccttgccctt caataccgtg ctgaatatct tgcccttcac
     4801 gccccacgtt atgtttgaca tacagcagga aagtgaagtg cggaacatca gggcgggtgc
     4861 agtcaacgac atcgctttca ctgtcaggcc tgacttggcc gggtcaaggc tgcatgtcac
     4921 cgtcgatgcc aatggccgct tgtactccgc gagcgacctg caaatgcatg ttagtggatt
     4981 gttgaacgtc gttcgcaccc tgatggcgca accgcaaatc catctgtcgg cgctgcctag
     5041 gcctaggccc atggcttggc tggaaggggc tcgagcttgc gcacgtcagg atgtactcag
     5101 ttcgattttc gaccgtgctc agaaccaagg aaagcaggtc gcgctgacag acatctgcaa
     5161 tccacaggag aactggcaaa gtatcactta tcaggtgttg gttgatgagg tcgagcggtt
     5221 ggctcattct ttgcgagagt gtgcggcttt tgatctgtta gtactagatt tgcctcgctc
     5281 cagcgattcc atccttttca tgctgatagc tctgcgcttg ggtgtgcctt tcgtcgttct
     5341 caatcccatg agggcgcaac agatgctaga ggtcctggtc cagcatgcta ctcacgcctt
     5401 gctggtggcc aggcaggaag tatctagcga ctctgccggg tggcaggaaa gtgcgcagta
     5461 cctgcagata aaaggatatg aggcactgcg cttcacgcgt ttgcagggtg agggcacaag
     5521 cggattcggt gcgcttgcct acttgatgtt cacatcaggt accgctggta aggccaaggc
     5581 agtgaagata tctaggcaag caatggatgc gtttgtcggc acggcggtta atcgatatgg
     5641 cttcgacact acggatgtag tactcaactt ctcggagcat tttttcgatg cctgcattga
     5701 ggagattttc ggggcattga ccgccggtgc tcggctggtg attcgtccag ccgatgctca
     5761 taggtcgacg cggcatttcc tcagcttctg tgctatgcag gcgatcactg tccttgactt
     5821 acccacagcc tattggcatg aaatggctat tgccatggat gcccatatga tgaagcgtac
     5881 ccgggtacgc cttgtggtca tcggtgggga gcgtgtgtcc gagcaggctc tataccattg
     5941 gttcgagaaa gtcggtgata gtccccagct attcaactcc tatgggccga cagaggctac
     6001 tgtagttgcc acctgtgcat tgctggacaa ggcagaaggg gcttcgatag ggcgcccctt
     6061 agccggagtg cagtgcgcga tcctgggccc tgggctaaca cttctgccac aaggagcgag
     6121 tggtgagctg ctgctattcg gtgatacgct cgccgaaggt tacctaggtg atgcagaacg
     6181 cactacagaa agattcgtcg agatctgcat cgatggaaaa atgcgtcgtg gctaccgcac
     6241 tggtgatcta gcactcctag gcagggacaa ccagttgcac tacatgggcc gcctagacca
     6301 tgaggtgaag atcgccggtc aacggctgaa tctgtctgag ctggaggcct tgatcgaagc
     6361 ctgtgccgga gtcagggaag tctgcgtcgt actgcaagaa agtatctttc ctcggtcact
     6421 gagcgcgcat atctatggtg atccagcact agagcagacg gttcgccgag acttgggctc
     6481 tcagatagcg cctgagttcc tgccgcgcag ctatcactgg catgcctcgc cacttcccaa
     6541 aactttctcg gggaaaatcg atcgtgccca gctccagcgc catggcaaaa agacgccccc
     6601 cttgtccttg ccaaagattg ttgagcggca gggctggctc gagcagcatg tgcgcatgat
     6661 ctggtgcgaa agcttgggaa gcaatgaggc tctcgatttt tttcagcagg gcggtgactc
     6721 gttaatggca ttgcgtatgg tcaaccggct gaatgccgaa ctcggcttgg cattgactat
     6781 ggagacggtg tttgattcga agaccctgaa gggactactt gcctatattg ttcgggaaat
     6841 aacgaaactc ggtttgcaag ttgattgctt ggaactgcgc aatgcattgt tgaaaccacc
     6901 ttctcctgtg caatggtcag ctcggcgcac ggttttcctc gaagcgcatc cgctgcacca
     6961 ctttgctgat ctgcaaggat tggccgaaaa gctggacctt tacttggtcg tgagtcgtaa
     7021 tgacgatgct cagccagtgg gcaaagactg ctctgtccaa gacaggctgt actggcacga
     7081 tgtacagggc ggcttatggc atcaaggcca agcttggcct gtgacacaga tacccgcagt
     7141 gcaatacgca atcttcatca tgccgcaccg tccagaagcc tatccggctt ggtcgcagcg
     7201 atgcctggaa aggctcaggc aactacagat gcacaatctg gagcgtgcac tgatcgttac
     7261 cgatcgggag ggccggcgct ggttcgaaaa acacatcttg tcggctgcgg aatgcaaacg
     7321 gctggaattt cacacatgtt cacctcacgc gctgcaggag cggcaacatc aggaagaact
     7381 gatcgtggac tggtctgtgc gtataggtta cttcccagat ctgaacttgc cgccatgctt
     7441 cgtaagcatg cgtaatctgc ttgctgaatt agccggccgg ccagggcggg tacgcatgtc
     7501 tgttcgggat cgcctgttcg cacgagcgca aagtttcaac cccgatgtga aagtctgtag
     7561 ctttgcccaa tggctgaaag aaatcactcg atactcaggg agcccctgcc ataggttgga
     7621 gcagcgcact gtataccgtt tgaacttgtg aacaacaact gcacaccaag gagcaggttg
     7681 tggatataag agaaaagaca ccgaattggc cagagtcttt caatcgcttg tatattgaaa
     7741 agaactactg ggctgaagag accttcgttt cgttgctcga tactgatgca cgacgtattg
     7801 cctattcacc ggcaaatgtg ggcggcgagt gcaccattac ctaccgacaa ctccgcactc
     7861 ttaagtactc ggtcttcaag agggcgcgcg gcagagcact ggaattggat gacctgttca
     7921 aggaccagat caacaagggt gccgagaaag tatcacctga gaaggcggag gatgtgatca
     7981 tcaaaactgg ccttgtcagt gatgcggttg ttgtcgcgca agtggatgag tacgtgggcg
     8041 ataggatcgt cggtattgtc atcgccaact caagcaccaa tcttacggac ctcaagcgcc
     8101 acttgcatgg catcatggcc aattataagt taccggatgt cttcattgag gttgagcact
     8161 ttccaacgac gggggttggc aaactgagtc gcagggcctt aaggcaacag gtccagctgc
     8221 aattgctcaa ggccaagaaa tgctgacagt caatgaagaa caaaggctgc aacgcaatga
     8281 gatcagagcc tttctgcttg ggcaggtcag tgctctgtgt ggcttgaatg agatacccga
     8341 cgaccaagtg ccactaattg aattgggaat ggactcggtt cgtttgctta gcctgctgga
     8401 agccttgcgc cgtcagggtg tggcgttggg gttcatcgat gtcatggaaa acccctcgct
     8461 gctagagctc gaacagttgg tcgcggagcg tttgacgaga caaactcacc cataatgaac
     8521 gcgcttaggg aaaattcgaa caagttcttt tttcgcacga aacatccctg aaaaccgcgt
     8581 aattgctagg gcctcttgtc aaatggcgac ttattcggag tttccctagt gagaagatgt
     8641 gccgggagaa tagaaagtgg atatggatgg cttgtctgca ctaatcgaat tagcggaaaa
     8701 aggatgggca ttcgagcggg tcagtgccga gcgcttggat atttgtcggt cgactaataa
     8761 tgaaggcgag gcactgtggc agcatagcaa agcgcagatt tttgagtttt tgagtgacac
     8821 cgaaaaaagt caagatgagc ggacaggtat ccgttcggtc aggccgggcg aaacgtttgt
     8881 ggtaaaccgt tatgctggcc agtatctatg ggtgttcgat aacctcagac accatagtgc
     8941 gctctacaat attccgttgt gcaagcggat aagcgggtca gtggatgtag agcgcttaat
     9001 ttacgcgttg tctcgactgg tgcagcacca tggcatcttc gctacggtct atcagttgca
     9061 ggaggcacag ttgcatatgt ctactagggt attacctacc agtttgtttg ctgacgccct
     9121 gaccgacatt tcgggactga gtacttcaca acagcagcaa tggttggaaa acttcacctt
     9181 ggaatgcagc cagtgtgcgt tcgatctcag ttgtgaggtt ccaatccgct gtcgtatcgt
     9241 tcgtactaga gatgacgagc attggttgtt cctgacgttc catcattcgg cggtcgatgg
     9301 ctggtcgatt ggtcagttcc tcaacgagtt gagcgccacc tatcaagatc tctctttcgt
     9361 accggactgt ttacccgctg cttggagtta cgctcagaat ccgtttgcct tcatagcctc
     9421 ggtcgacgaa agcttggcat tttggatgaa ggaacttgag catgctccgg ctcgccacgg
     9481 cctagcctat gatgctgtag agaagcatac tgatttacac aaaaacgtag tgacttcgat
     9541 actttccgag gcctctttgc aatccttaaa aggcttttcc cgggcccatg gggtttcgat
     9601 ctcggttgta ctgcaagcca cctttgttct actgctatcg aagctgagtc ggcaacgtcg
     9661 tattgtaatc ggtactccag tggccaatcg cccccatgtt gaacttaaca ctgcattggg
     9721 tagttttgta aacactattg cactttattt taatctagag gaagtacaaa gcttttctga
     9781 tcttgtgcaa gtagctcaag ataaattaat acgctcgcat ccgcaccatg gtttgccatt
     9841 ctcctacgtg gttgagcagc ttcgtccaga acgtggtgat ttcaatccaa tttaccagat
     9901 tcttttcgtt tgccaacacc agcaggatag ccacctgcag tttgtggatg cacaagttca
     9961 tgatgtacaa cgaacctact caacccctaa aagtgacctt gcactcgagg tcatcctgca
    10021 ccaggatagg ataacgttgg agtggcagtt ccatcccaac tacttctcct ttgacaggat
    10081 tgcgtcgttt gcccagcatt ttctcaactt gcttgagcag gttatgaagg ctccctcact
    10141 accgctaggt tgcttcggtc tcatgtctcc gaagcgaagg aagaccttac tcgaactgtc
    10201 gatgggggac caggttgatg tgtttgttgg acaaacactc gatcgactga tggagcagtc
    10261 aaaatcacgt ttcgccgaca atattgcggt gatcgatggt aatgatcaat atacctatgc
    10321 gcagctgttt gccggtgcta agagcctagc cggatatctt gactcgctct gcgagccaca
    10381 ggcgattgtc gctgtccaga tcaagcgggg ctatctgcag gccctgctgt tgcttgctac
    10441 cgtgcttagt gggcgagttt accttccgct ggctatggac acgccgatat cgcgtgcccg
    10501 cagtatcctt gagtcatcag gttgcaccct gctgatcggc gatgtgctcg atgaacagat
    10561 gtacccaggt attcgggtat tgccctcgcg gatactgtgg tgccagcttg agcatgctcc
    10621 atttacccgt gatacatcga tcagcccctc tgatttagca tatttgatct acacctcggg
    10681 aaccacaggg acacccaagg gcgtcgccat cgaacatgcg gcggtgtgca atacactatt
    10741 ggcaatgaac caatatttcg gcgtgtcgca acacgacagg gttttggcca tttccaacat
    10801 aagtttcgac ttatctgtat atgacctgtt cggtacttgg actgctggtg cctgcgtggt
    10861 cctgttgtcc gagtcggcaa gtaaggatcc tgccagttgg gtacaggcca ttcatgcgaa
    10921 ccacgtcagc gtatggaact cagtgcccat ggtactacaa atgatgctcg ctttcgttca
    10981 ggggttgaga ctgaatacct ttccgggagt ccgacacatt tggttgagtg gcgattggat
    11041 tccgccgaag ctaatcgaac aggctagatg ctgctttcca caggccaaaa tcattagctt
    11101 gggcggagct accgaaggct ccatctggtc gatctaccat ccactgcaag accaagtcta
    11161 ccttggcagt atcccctacg gtagagcatt gcccaaccaa ggtatgttcg tcctagatga
    11221 acaactggag ctttgtgatt tcggggtcag tggcgatatt tacattgctg gttacggtgt
    11281 cgctcgaggt tatcaccaag ccccccggtt gaccgagagt aaatttaccg tccatcccca
    11341 actgaagcag cgcctataca agaccggtga tcgtggacgt tggcatacag cgggttacat
    11401 cgagtttctg ggacgggagg acaagcaggt caagatccaa gggtacaggg tcgaacttgg
    11461 cgaagtcgaa tctgtgctaa aacgcgctag tttcgtacgt gatgcagttg tgttgattcg
    11521 atcctcaacg gggggaggcg gttcctacct agaggcccat atcgttgcgt cgccgttgac
    11581 agcacagtta gagccgacgc ttcgagcaca tgcggcattg ctgctaagcc cttacatgca
    11641 accgttgcac tatggttttt atgagcaatt cccgttgtcg gccaatggca aggtggatac
    11701 tagccgcttg aggaggctgg caccgatgcg tgcgtcatcc acttctggat gggatgcgga
    11761 tgaacacctt ttcaagctca tggaaattgt ttctgtggtt ctagacagac caatggcgga
    11821 gctcgatcca cagcacagct tctatcagtt gggcggcaca tctctgcagg cggttagtct
    11881 ggcagtcaaa ggagccacgc attggcaagt taacctatcg atcacggaca tcttggaggc
    11941 gtcctcattg gtcgagctgg ctgagaagat ccgtgtggta cctctggttc tgtcgaagct
    12001 atcgactttc gagcaggctt ctgttggcgc cttgagtttg tgcttcgtgc atgctgccgg
    12061 agggcatctc gagccatatc gcacactcca gacacgctat gcggggcgtt gcaatctgtt
    12121 cggattgagc agccctgcat tggccagcat cggtcctgac tgcgaactgg cttttgaagc
    12181 gttgctcgaa gctcatgtca attcgttgct ggacattccc agtcaagggc acttggtgct
    12241 ggttggctgg tcattgggtg gcattctagc gatgaacctg tgtgaacgct tggtgcgcca
    12301 tggcatcaga gttagacatg tagtagtagt agactcgggt ttggattatg cgccaatggt
    12361 tggcaagggg cgcaccaagc agtggttgag actggtcgcc aatgcggtgg agatgtacgg
    12421 actcgacaag cactgcctga tagtgaaagg ggctgagggt ttcagttcgt tcgctgggct
    12481 gcttaagtac ctctataccg tcaatgagga gaaactgagc gctgtgctct caagatccca
    12541 gtttgaagtc agcgcctggg ctttggagcg agcatgtcgg ttattggccg aggcgagtat
    12601 cccgaagctc gatacggctt tgagtgttca cttgtgccag acccatcaga ctattgcttc
    12661 atcgcagatt ctgcgttggc aggatctgag tcctaaggtc gatatcatcg agctggctgc
    12721 tgagcataat agtatcctta gtgtaccgtc ctttctgcgc tctttggaca gcttgctcga
    12781 aagtttacag gtttcggaag gtaaagcaat tgacacggcg aacgggtagg tagagagccc
    12841 gttgcaggct ggatagcatt tcggtgcgtt tatatagatg cctcccggaa cgtaataata
    12901 gtagccatgc tggtgttttc agggccagca tcaattggag atttctggca tttggggcgt
    12961 agataaatct gttcgactac atctgctttt acaatcagta ctgccgtcat ttaatgctgg
    13021 gctattccat cccgatggag tctgaacgga gatgtatgag cagtagtttt aattttctgt
    13081 ccagcggctc cccaatagac caagctgaaa tttctcgaaa caaggtgcga aaactaaaag
    13141 ttacttaatc gcttgccttc ctgcaaattg aaaccaaata tactagtctc actagacaga
    13201 tattgtttag agcgtcttct agaagaagga aagccaagcc atggaccgga tctattttca
    13261 cttctctccg tcaactcacg gctgccaaac gctgagttgg accagttgat gtgtctgtag
    13321 aagctgcgct cctgacaagt agcgttacac catctaaaac atagaataaa tttgtcccac
    13381 tcactccctt gatcagtatt cgggtagata gtgatttaat tgagtctgac atgacatgtc
    13441 tgactcaatt aacacattaa ttcaactaaa gagtgcgaat ataatgaatg caactacgaa
    13501 tagtctgctt gtcgatgcta taagcaaacg ccacgcaaat tctgaaaatt ttaaagagtg
    13561 tctctctcct gctcaaatta ttgcggaata catgttagga attgaaacaa taaattatgg
    13621 tgaggatgag ttgatagcct caactagtct ttgtacgcag tgttggaacg catgctgcct
    13681 aacgtcatac tcgaccgatt ccgtaatgaa cggaacttgt atgtgcacct ccgaagaaaa
    13741 aaatggagta gttgttttcc actaagtcaa aagcgcgcca cctgggtggt ggcgcgccca
    13801 ttaaaagaga aacagaagtg atatacgcaa cagcaatcaa tggtggcgat tgtgttactg
    13861 cagcaaatta taatggtaaa catagggttc ttgttgaggt aataattaat gatatcctag
    13921 aaagaacatg ttttgataag cgcaaagata tccatagaaa gcttgtgaca gcactggctg
    13981 gatatgcagc aaataaaatt gatctatata tgaggcatgt tttggagttt gagcttgggt
    14041 ccctgtctga ggtactggaa aacgttaatc tagactacat aatggatagt gatgaattat
    14101 atattgcaat tttaaaaaaa tatccaggtc ttgagccact ggtagatcat cttgggtctt
    14161 cgctgataga aaattttaca ttgataataa aaagctttga ggatgcagaa tttgaactcg
    14221 tgagtaatgg ctatttgagt tcggtaaata atattacaaa catcttcttg ttgagcgatg
    14281 aaagtcacga tgctaataag aatattgtgc ttttttatga tagctacaaa cctgcgtttg
    14341 ctctaaagtt acgaaatata actttggaaa agcaaactaa tgattttata tctggttttc
    14401 taagagaaaa tatgggtttt gaggattgga attttccaaa ttatcttgat catggtgagg
    14461 ttggttgggt aagttggcga cctcgtcagg acctcaatag tgaaaagcag attacggaaa
    14521 gttattttag atcgggggtt cttgcttcaa ttagttgtgc tttaggtata acagatctca
    14581 atcatgagaa tataattata catgctggct ctccagtcat tgttgatctt gaaacaacat
    14641 tacatcactg tgttgaaggg ggcggtagca ccaatgcttt acggaccggc ctgtttccaa
    14701 gcttccttaa gctcgacagg aatggctcgc caacggaaga aagttgtggt ataggcaaca
    14761 tttttccaga gtatcgttta aaaagtaaga ataacgaggt ttgtttcgat aataaaatag
    14821 ctagcccaat tgactatata gagtatatta aacaaggatt gcgacttggt tttgctaaag
    14881 taattcagta taaagagaaa ttcgtagatc acattgtaag aatagaaaac tttaggacta
    14941 ggttcatttt caaagctaca tatagctacg ccactattat tgagtcatca atgcatcctg
    15001 cccttttgaa gtcggcagtt attagggagg aatatatcac gcaatgtttt gaatcggaaa
    15061 acaaatatgt tgaaggagat gaggcgaaat ggggagaaat aaaagcttgc tatttgggcg
    15121 acgtaccgag atttataaca accgcaaatt cattaattct tgattcttat tatcaacaaa
    15181 caccaacaac attacgccat atatgtacag gtgtgtcaag gacgctacaa tatcttcagg
    15241 atctaaatga caaaatcgta gatgaggaga tattttatat cgagaagagc tatgccgaag
    15301 catatagggt gatgtcagtt aatgccaaaa gctatgagat agaaaactat caaaagctaa
    15361 taaattgtgc aaatgaattc gcactaaata ataaaatgcc cgtgttcttc atgccgagaa
    15421 atgattattg tttagagtta aaatcctgtg ggctagatat attttccggt attggaggca
    15481 ttgtgtattt ggcagcgatc aagaaattac ccgttgaaag cacgattagc gatcgaataa
    15541 tagcaaatta tatcgaacga ctcaactcaa ctcaacgaaa ctag
//
