BGC0002529 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002529 (Azotobacter vinelandii CA)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	15,584	aminochelin/azotochelin/protochelin	NRPS:Type I	100%

BGC0002529 - Region 1 - NRPS

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Location: 1 - 15,584 nt. (total: 15,584 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,585
Label		BGC0002529

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002529	1.00	NRP	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0000901	0.26	Other	ferrichrome	Aspergillus niger
BGC0000313	0.25	NRP	beauvericin	Beauveria bassiana
BGC0002135	0.24	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002518	0.24	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0000343	0.24	NRP	enterobactin	Pseudomonas sp. J465
BGC0001131	0.24	NRP	ambactin	Xenorhabdus miraniensis
BGC0002437	0.23	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0001132	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000396	0.23	NRP	nodularin	Nostoc sp. 73.1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002529	1.00	NRP	aminochelin, azotochelin, protochelin	Azotobacter vinelandii CA
BGC0000901	0.60	Other	ferrichrome	Aspergillus niger
BGC0000313	0.59	NRP	beauvericin	Beauveria bassiana
BGC0002135	0.58	NRP	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002518	0.58	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0000343	0.57	NRP	enterobactin	Pseudomonas sp. J465
BGC0001131	0.57	NRP	ambactin	Xenorhabdus miraniensis
BGC0002437	0.57	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0001132	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000396	0.57	NRP	nodularin	Nostoc sp. 73.1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15584:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AvCA_09680

AMP-binding (446..847): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAEDVGSVVK
Nearest Stachelhaus code(s):: Lys DIEDVGSVVK (71% 8Å match)
Stachelhaus code match:: 90% (moderate)

AvCA_09690

Search NORINE for peptide: strict or relaxed

AMP-binding (533..925): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNWSLIWK
Nearest Stachelhaus code(s):: Cys DLYNWSLIWK (85% 8Å match)
Stachelhaus code match:: 100% (strong)