BGC0002535 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002535 (Streptomyces celluloflavus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NAPAA	1	15,242	γ-poly-L-2,4-diaminobutyric acid	NRPS:Type I	100%

BGC0002535 - Region 1 - NAPAA

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Location: 1 - 15,242 nt. (total: 15,242 nt) Show pHMM detection rules used

Region on contig edge.

NAPAA: (AMP-binding and TIGR02353)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 15,243
Label		BGC0002535

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002535	1.00	NRP	γ-poly-L-2,4-diaminobutyric acid	Streptomyces celluloflavus
BGC0002174	0.33	NRP	ε-Poly-L-lysine	Epichloe festucae
BGC0000860	0.25	Other	ectoine	Methylarcula marina
BGC0000859	0.25	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855	0.25	Other	ectoine	Methylomicrobium kenyense
BGC0000857	0.25	Other	ectoine	Methylophaga alcalica
BGC0000858	0.25	Other	ectoine	Methylobacter marinus
BGC0000856	0.25	Other	ectoine	Methylophaga thalassica
BGC0000852	0.25	Other	ectoine	Sporosarcina pasteurii
BGC0000919	0.23	Other	phaseolotoxin	Pseudomonas syringae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002535	1.00	NRP	γ-poly-L-2,4-diaminobutyric acid	Streptomyces celluloflavus
BGC0002174	0.66	NRP	ε-Poly-L-lysine	Epichloe festucae
BGC0000860	0.59	Other	ectoine	Methylarcula marina
BGC0000859	0.59	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855	0.59	Other	ectoine	Methylomicrobium kenyense
BGC0000857	0.59	Other	ectoine	Methylophaga alcalica
BGC0000858	0.58	Other	ectoine	Methylobacter marinus
BGC0000856	0.58	Other	ectoine	Methylophaga thalassica
BGC0000852	0.58	Other	ectoine	Sporosarcina pasteurii
BGC0000919	0.56	Other	phaseolotoxin	Pseudomonas syringae

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 15242:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

pldA

AMP-binding (37..430): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFECLSAVTK
Nearest Stachelhaus code(s):: Val DFESLAAVYK (62% 8Å match)
Stachelhaus code match:: 70% (weak)