Search NORINE for peptide: strict or relaxed

PKS_AT (949..1259): mal

ATSignature: Malonyl-CoA

Top 3 matches:

Malonyl-CoA: 70.8%

Methylmalonyl-CoA: 66.7%

Ethylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 69.2

Methylmalonyl-CoA: 69.1

Methoxymalonyl-CoA: 60.0

Isobutyryl-CoA: 44.0

Ethylmalonyl-CoA: 43.0

Propionyl-CoA: 33.4

Benzoyl-CoA: 32.0

3-Methylbutyryl-CoA: 27.6

trans-1,2-CPDA: 24.5

2-Methylbutyryl-CoA: 13.7

inactive: 10.2

CHC-CoA: 9.7

Acetyl-CoA: 7.7

fatty_acid: 0.0

AMP-binding (1906..2302): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:

N/A

Large clusters prediction:

N/A

Small clusters prediction:

N/A

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DAVLIIGVAK

Nearest Stachelhaus code(s):

Leu DALLIGAVAK (53% 8Å match)

Stachelhaus code match:

70% (weak)

AMP-binding (2986..3386): Abu

nrpys: Abu

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DLGYLAGCFK

Nearest Stachelhaus code(s):

Abu DLGYLAGCFK (85% 8Å match)

Val DLGYLAGCFK (82% 8Å match)

Stachelhaus code match:

100% (strong)

AMP-binding (4074..4477): X

nrpys: Abu, Val

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DLGYLAGCFK

Nearest Stachelhaus code(s):

Abu DLGYLAGCFK (94% 8Å match)

Val DLGYLAGCFK (94% 8Å match)

Stachelhaus code match:

100% (strong)

AMP-binding (5166..5566): Abu

nrpys: Abu

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DLGYLAGCFK

Nearest Stachelhaus code(s):

Abu DLGYLAGCFK (91% 8Å match)

Val DLGYLAGCFK (88% 8Å match)

Stachelhaus code match:

100% (strong)

AMP-binding (6260..6663): Ival

nrpys: Ival

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DAGCICGVFK

Nearest Stachelhaus code(s):

Leu DLGFLCGVFK (71% 8Å match)

Ile DAGFIGAVFK (53% 8Å match)

Val DALWIGGVFK (44% 8Å match)

Stachelhaus code match:

70% (weak)

AMP-binding (7363..7752): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

N/A

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DIGMISGIYK

Nearest Stachelhaus code(s):

Ala DVGMVGGIYK (71% 8Å match)

Stachelhaus code match:

70% (weak)

AMP-binding (8435..8831): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:

N/A

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:

DAFLMGAVMK

Nearest Stachelhaus code(s):

Leu DAFLIGAVMK (62% 8Å match)

Stachelhaus code match:

90% (moderate)

AMP-binding (9516..9918): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DMGFVAGICK

Nearest Stachelhaus code(s):

Ala DVGFVAGVLK (71% 8Å match)

Bmt DMGFLAGVFK (68% 8Å match)

Trp or Pro DVYFVGGICK (59% 8Å match)

Pro DMTFSAGIIK (53% 8Å match)

Stachelhaus code match:

70% (weak)

AMP-binding (10605..11006): X

nrpys: Abu, Val

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DLGYLAGCFK

Nearest Stachelhaus code(s):

Abu DLGYLAGCFK (97% 8Å match)

Val DLGYLAGCFK (97% 8Å match)

Stachelhaus code match:

100% (strong)

AMP-binding (11706..12095): X

nrpys: Pro, Hpr

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)

Small clusters prediction:

N/A

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DWMFGGFINK

Nearest Stachelhaus code(s):

Leu or Trp DAMFSGAIFK (50% 8Å match)

Trp or Pro DVMFIGAVNK (47% 8Å match)

Stachelhaus code match:

60% (weak)

AMP-binding (12785..13185): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:

hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)

Large clusters prediction:

Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)

Small clusters prediction:

glu,gln (Glu, Gln)

Single AA prediction:

gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:

DGGMIGGNYK

Nearest Stachelhaus code(s):

Ala DGGMIGGNYK (91% 8Å match)

Abu DGGMIGGNYK (82% 8Å match)

Stachelhaus code match:

100% (strong)

AMP-binding (13868..14271): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DMAFLAAPFK

Nearest Stachelhaus code(s):

Bmt DMGFLAGVFK (65% 8Å match)

Stachelhaus code match:

70% (weak)

AMP-binding (14960..15354): X

nrpys: Pro, Hpr

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)

Small clusters prediction:

N/A

Single AA prediction:

N/A

Stachelhaus prediction details:

Stachelhaus sequence:

DWLFGGFINK

Nearest Stachelhaus code(s):

Pro DVLFCGLICK (62% 8Å match)

Stachelhaus code match:

60% (weak)

AMP-binding (16045..16446): Ival

nrpys: Ival

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)

Single AA prediction:

iva (Ival)

Stachelhaus prediction details:

Stachelhaus sequence:

DLGFLAGCFK

Nearest Stachelhaus code(s):

Abu or Ival DLGFLAGVFK (91% 8Å match)

Aib DLGFLAGVFK (88% 8Å match)

Stachelhaus code match:

90% (moderate)

AMP-binding (17151..17548): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:

hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)

Large clusters prediction:

Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)

Small clusters prediction:

N/A

Single AA prediction:

ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:

DGFIMAGIMK

Nearest Stachelhaus code(s):

Phe DGYCMAGIMK (44% 8Å match)

Stachelhaus code match:

80% (moderate)