LOCUS       BGC0002560             11767 bp    DNA     linear   BCT 18-SEP-2015
DEFINITION  Streptomyces sp. NRRL S-4 P198contig2.1, whole genome shotgun
            sequence.
ACCESSION   BGC0002560
VERSION     BGC0002560
KEYWORDS    .
SOURCE      Streptomyces sp. NRRL S-4
  ORGANISM  Streptomyces sp. NRRL S-4
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 17:59:53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 86913
            Orig. end    :: 98680
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1011)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251:luciferase family
                     protein (Score: 87; E-value: 2.2e-26)"
                     /gene_kind="other"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_019630302.1"
                     /locus_tag="ADK82_11800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FMN-linked alkanal monooxygenase"
                     /protein_id="KPC82018.1"
                     /transl_table=11
                     /translation="MNIPFSVLDLAPVGSGSNSAQALRNTIALAEHVDRLGYARYWMAE
                     HHAMPGIASSAPAVMVGEIASRTSRLQVGSGGVMLQNHPPFVVAEQFGTLEALHPGRID
                     LGVGKNSGIDPAAVKALGLSEGNSSTEDFVRAVDELRQYFNDESIAVPAAGNRPRMWML
                     GSSMRSAKVAGLLGLRFAYAHHINPTGTAAALAAYREAFRPSRACTQPYALITAPVICA
                     ESDERARLLAEPGALAFLRLRNAAPGDKPQHFLPTPREVDSHAYSREERELVEQYFAAQ
                     VIGGPDQVRERLEALIKATLADEVMVTSMVHDHRDLMRSYEILASLLPMQVVAAD"
     subregion       1..11767
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="ribosomal"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11767
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1011)
                     /locus_tag="ADK82_11800"
     gene            complement(1143..1922)
                     /locus_tag="ADK82_11805"
     CDS             complement(1143..1922)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_020679280.1"
                     /locus_tag="ADK82_11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82467.1"
                     /transl_table=11
                     /translation="MLSVGQAVVVGVTLEVLLLGVVLAEIALARRTYRVSRAEGADGQQ
                     AVDEALRAVLPGPVAKAVGMELGLLRSMWTWLRRRRDIAPGQEPLSYGSQIRPVMWVMI
                     CLTPLEILAIELLLPWAAVRITLLVLALYGTVWVLGFLGALSSRPHVVGNGVLTLRFVH
                     FVSVSVPLRGEVSVQEVRHSGYKKAVNIKDGILAMPIGDSTNVAVTLSAPVPVRPKPGA
                     PEQEISEIRFSADDPGAALTLLQGYNLQVPSEGRTSE"
     gene            complement(2248..2550)
                     /locus_tag="ADK82_11810"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(2721..3536)
                     /locus_tag="ADK82_11815"
     CDS             complement(2721..3536)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_014406686.1"
                     /locus_tag="ADK82_11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82019.1"
                     /transl_table=11
                     /translation="MSTSTADPGTVDRDYLTRLRPPWWTSGGPAPARIDLAAWMPPVVN
                     QGPVALCTAAVTTAIAGYYVRRTSREEFTPSVLFNYRASRALRGNPDSNGSRLEHSFRA
                     WAESGLCAEELWPFDPAQPDRVNRNPPQRCHDAARHSSPVGRRVAASDGAELHRTVRRA
                     LALGIPVGVEIRLCPSLSMSLINGGIMPVQTEGEASVGPHVILLTGYDDDVDTEPWGRG
                     SGPGAFRVRNSWGADWGQEGYGLLPYAFLTRRLVGETWIVIEEDWEQTA"
     gene            complement(3533..4204)
                     /locus_tag="ADK82_11820"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(4372..5094)
                     /locus_tag="ADK82_11825"
     CDS             complement(4372..5094)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018962009.1"
                     /locus_tag="ADK82_11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82020.1"
                     /sec_met_domain="TfuA (E-value: 1.1e-43, bitscore: 137.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIPTTVGVNAPRLSVFLGPSLPVEQAREHLPGAEFLPPVERGDI
                     DALMARADPPTHIGIVDGKFLQSFSISPKEILKAMDRGVRMYGSSSMGALRAAELDVFG
                     MTGIGTVYDMYASGEIEDDDEVAITFDSEVMRLICEPMVNIRVATAEAVRREIVEPKYA
                     DLFLETAKALYFPQRTRAAALHEVKGRMPEEQRMALASFLRSPEAPDAKGEDAARLLDV
                     MRRAAEDVPPPADSRGAA"
     gene            complement(5091..6458)
                     /locus_tag="ADK82_11830"
     CDS             complement(5091..6458)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018962008.1"
                     /locus_tag="ADK82_11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82021.1"
                     /sec_met_domain="YcaO (E-value: 6.2e-77, bitscore: 248.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRQSVPKITGNGPHREYTSETTYRRIAPHLRRVGVTRVANITG
                     LDRVGIPVYNAISPRSFDIISVYNGKGATEIDAKTSAVMEAVERFAAGLPMRPVAVASY
                     TELEASGRRVLDPRSCNFEFHRAYTLDTPICWVEGFDLLNECAVLVPQFLAGYYLNFHE
                     VPCYPVSTTNGIASGNSLEEAICHALCEVIERDDWTMADLVSNRLAGFAAQEDGTPIGT
                     AISAWAQDLHPSVDPDSLPERAQFFMDKFHAAEIDIEVKNITSATGIPSFQAVVSEFIS
                     DSFSRSHHGIGTHPDAEVAVVRAIAEVAQSRVVDIQAMREDITAAGEPVEKALYHVRRS
                     NRANPDAWAIKPSSRPVRLQDVPTHPSSDVMDDVRTLLDRLRARGLDQAIVVDLSPPAV
                     PATVVRVIVPGAESWTVDRNKIGPRAREAWDGTLNTIRSAYAKRQQRTTGEQESNA"
     gene            complement(6487..7605)
                     /locus_tag="ADK82_11835"
     CDS             complement(6487..7605)
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_018962007.1"
                     /locus_tag="ADK82_11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82468.1"
                     /transl_table=11
                     /translation="MLKLGQSALGLLDLFHTPRTIGQALTLLSARLKGPRATEQALATV
                     LALHQAGVLCSDPVEGFSSQPFPKGGYDAALVHIAMLDDPVRKTAFQQGVRETVREGDV
                     VLDLGTGSGILAITAAQAGARKVYAVEPAGMVHLARSIAERNGVADRIEFIRGWSPQLE
                     LPEPADVLLTDIVGNEALDMQIWETLHDARRRLLTDSPRLVPGALTAYATLTRIPDALL
                     DQHRVSDEHVTRWKDMYGIDFGPMAESESRRSIGFYERPETVQEWEFLSAPGELYEVDL
                     LGDAPRQLETACTLTANGEGVANGVTVHFTARLGPTTQLSTAPWMGCSRSHWYTAVWAF
                     PEPVPVRAGQQVNLDYRYFGDGTSHVAPSAAA"
     gene            complement(7839..8324)
                     /locus_tag="ADK82_11840"
                     /note="hypothetical protein; disrupted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
     gene            complement(8321..9313)
                     /locus_tag="ADK82_11845"
     CDS             complement(8321..9313)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="ADK82_11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /product="hypothetical protein"
                     /protein_id="KPC82022.1"
                     /transl_table=11
                     /translation="MSTQETGGTSGSDRSGKGAAKRQVVRHLPGPFLTRVCIRTDDGFR
                     WGESLRAASPAYLDAEALGAVARSVAVTPAAPYAVMPTLADACTSVHAEVPTPALLSDV
                     VFTGDGCARSWVQGAFRHLGAFLAHLHAVSTEGEALPVRRRAAWLDAEPAVASGIQEAR
                     SLLARTVPPGTALSGRPDSSPPCTGPGTTPAPASTLVHGRLSTASCVPGPVPRVLGWRE
                     AGVGDPMGDLAYLLRDLVQSAAGTGDTGAKAGCAKVAVAGYEEARDASLTPCELARLAS
                     ATASCVLDHAALRAWAASDQPGALALLRRADRVLPEILAAVGYRRVTTA"
     gene            complement(9310..10218)
                     /locus_tag="ADK82_11850"
     CDS             complement(9310..10218)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_008056038.1"
                     /locus_tag="ADK82_11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82023.1"
                     /sec_met_domain="HopA1 (E-value: 4.7e-48, bitscore: 152.6,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METEPGTLPVLAHLWRFLYLSYYAGDARAARWLIDGAPVVLGTTR
                     REDPEVGALLSVANQAVGYPEPGWVVTGRADGSVTVLKDGVTLTATEEQIVPSQEGTSL
                     SPGQQVSVVMPSGRPYLYPGWYLAVSDHGMPSHGELPVVRLYFAPRDPRSGATLLRSLT
                     GLLCGLGVPYQIKSANNPEGYERCDPLVLYVYRHDWERHRAALAAVHRDHESRLRDAGP
                     CFALELARGWWIADEPDQYGGRLMSFGQHRCLLAAEGLVTAWQEGRTGTAGRLGAIRER
                     YRAEGIEPARPYLNARPSTSI"
     gene            complement(10323..11186)
                     /locus_tag="ADK82_11855"
     CDS             complement(10323..11186)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_015211015.1"
                     /locus_tag="ADK82_11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="KPC82024.1"
                     /sec_met_domain="APH (E-value: 1.8e-18, bitscore: 56.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRLVPVAGLPVVSERAIPRLVATDPESGTLVMEGKVGFASLREL
                     VQSSPDIPVSVLVAMASVVAGIHRTPVPDTHGRDASGLRSFGFPFASFAVLTPEQLVGG
                     PGMDYPAYVAAMQAVDTEVDMLRRSWQPSSLVHFDLRDDNILVRENADDRPEVALVDWE
                     MAGYGDPLLDVGTVVGQLLVQWLQTVRDTPEQLASAAAWTTVRRNAGLFITAYEHVAPL
                     SEEQHIAVFRYAGLFALMHAAGRLEQIGSLGRIGHLCLFVGRQLLKNPQGIAELFLPSK
                     GRSSRA"
     gene            complement(11501..11740)
                     /locus_tag="ADK82_11860"
     CDS             complement(11501..11740)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="ADK82_11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /product="hypothetical protein"
                     /protein_id="KPC82025.1"
                     /transl_table=11
                     /translation="MDEVAFSDLVSKIKEAELAMTDEQRAVIDPAAGEKALEELAGVSP
                     EDLQAFLEEKAGISPDEEAQGSVMAAIATVAYHC"
ORIGIN
        1 tcaatccgcc gccacgacct gcatcggaag gagactggcc agaatttcgt atgaccgcat
       61 gaggtcccgg tggtcgtgca ccatcgatgt caccatcact tcatcggcca gcgtcgcctt
      121 gatgagcgcc tccagccttt cccgaacctg atccggccct cctatcacct gggcagcgaa
      181 atattgctcg accagttccc tctcttcgcg actgtaggcg tgactgtcca cttcacgggg
      241 agtggggaga aaatgttgcg gcttgtcacc tggtgcggca ttccgcaatc tcagaaaggc
      301 aagcgcaccg ggctccgcaa ggagcctggc cctctcgtcg ctttccgcgc agataacggg
      361 cgcagtgatg agcgcatacg gttgcgtaca cgcacgtgag ggacggaacg cctcgcggta
      421 ggcagccagc gcggcagccg tccccgtcgg gttgatgtgg tgggcgtagg cgaaccgcag
      481 gcccaggagt ccggctactt tcgcgctgcg catgctcgat cccagcatcc acatacgggg
      541 tcggttgcct gcggcaggaa cggcgatact ttcgtcgttg aaatactgcc gcagctcgtc
      601 gaccgcgcgg acgaaatcct ctgtggacga attaccttcg gacaggccca gcgccttgac
      661 cgccgccgga tcgatcccgg agttcttccc cacgcccagg tcgatccgcc ccgggtgcaa
      721 cgcctccagc gtgccgaact gttcggcgac gacgaacggc ggatgattct gcagcatcac
      781 gccgccggaa ccgacctgta agcgtgaggt gcgactagcg atctccccca ccatgaccgc
      841 aggtgcagaa ctggcaatac ctggcatggc gtggtgctcc gccatccagt acctggcata
      901 cccgaggcgg tcgacatgct cggcgagcgc aatcgtgttt ctcaaggcct gcgctgaatt
      961 cgacccggat cccactggtg ccaggtcgag cacggagaag ggaatattca tggcagaatt
     1021 ttagaagcgt cctgacggtt tctcaagagc ttcccattca attatttatc aggtgccggc
     1081 tcgaggagtg gcgcccggtg gtgcttcagt ttccggcaac ggtgcgcccg gaacactgcg
     1141 ggctactccg aggtgcgtcc ttcgctcggg acctgcagat tatatccctg gagaagcgtc
     1201 aaagccgcac ctggatcatc ggcactgaac cggatctcgc tgatctcctg ctcgggtgca
     1261 ccaggtttcg ggcgcaccgg gaccggggca ctcagcgtga ccgcgacatt cgttgagtcg
     1321 ccgatcggca tggcgaggat tccgtctttg atattgacgg ccttcttgta tccactgtgc
     1381 cgtacctcct gcaccgacac ctcgccccgc agcgggacgg agacactgac gaaatgcacg
     1441 aacctcagcg tgaggacgcc gtttcctacg acgtgaggtc ggctgctgag cgccccgagg
     1501 aagccgagga cccacaccgt gccgtagagc gccaggacga gcagggtgat tcggacggct
     1561 gcccagggca ggagtagttc gatcgcaaga atttccagcg gggtcaggca aatcatcacc
     1621 cacatgaccg gccggatctg actcccgtac gacagcggtt cctggcccgg cgcaatgtcg
     1681 cgtctgcggc gaagccatgt ccacatcgac cgcaacaggc ccagttccat gcccacggcc
     1741 ttggcgacgg gacccggcag aaccgcccgt agcgcctcgt cgacggcctg ctgcccgtcg
     1801 gcgccctcgg ctcgggatac ccggtaagtg cgacgggcga gcgcgatctc agccaggacg
     1861 acgccaagga gcagcacttc aagagtcact ccgacaacga cggcctggcc gacggacagc
     1921 acctcggacc acaccagcac aacctgtaag agaatcactg ccggggcggc ccaacgtgcc
     1981 gccgccttag cgtatttctt cacggtctcc ccctgctttg cgaagcaaga cggcatcttg
     2041 gcacatcatt atcgcgtttt ccgtgtacga catgatccgc aagcgcgctg taggccagtt
     2101 ttgttcgacg tgttcacggg tgtgaaaaca catctgatac cagtccggca agcccgggat
     2161 gccaccgtcg tggacgtagg cgataccttc ggtgccgagt tgttcgcgga cgggtgtggt
     2221 ggccatccgc gcgacggcgg cgccattgac actcagcagc aggatccctc cgggggtcag
     2281 gacgcgggtg aactccgcca gccacgcccg ctggtcgtcc tccgggatat gcgagaacac
     2341 cgagacgccg tacaccacat cgatgctcgc gtcatcgaac ggcaacggtg ggcggcgccc
     2401 ggtgacggtg aactcagcac tgtcggccag atgcacgcga caccagtcga tggcctgaac
     2461 gtcgacgtca acgccgtgga agcgagcctg atccgcctcg ggcatcacat ggcggagaac
     2521 gcgggcacag ccgcagccga agtccagaat tttctgacca ggtgcaccga acggcagccc
     2581 agccgtgtcg aacagtgccc ggatctcgcc actgatacgt cggccgaaga actggaacat
     2641 gccctcgtcc tccacccccg tcacacgggt acggaggtgc gcgggcggca cagggatcgc
     2701 tgaagatgca gcttctgccg tcatgccgtc tgctcccagt cctcttcgat cactatccag
     2761 gtctccccga cgagccggcg cgtcagaaag gcgtagggca gcaggccata tccttcctgc
     2821 ccccagtcgg ccccccagct gttgcgcacc cggaaggcgc cgggcccact gccgcgcccc
     2881 cagggttcgg tgtcgacgtc gtcgtcgtag cccgtcagga ggatcacgtg agggccgacg
     2941 gatgcctccc cctcggtctg gacgggcatg atgccgccgt tgatcagcga catggacagt
     3001 gacgggcaca gccggatctc cactcccacc gggatgccca gtgccagggc gcggcggacg
     3061 gtccggtgca gttccgcgcc gtcggaggca gccaccctgc gccccacggg cgacgagtgc
     3121 cgggccgcgt catggcaacg ctgcggcggg tttcggttga cgcgatcggg ctgggccggg
     3181 tcgaagggcc agagctcctc ggcgcacagc cctgattcgg cccaggcgcg gaagctgtgc
     3241 tcgaggcgtg agccgttgct gtcggggtta ccccgaaggg cacggctggc gcggtaattg
     3301 aacaggacgg acggggtgaa ctcctcgcgc gacgtgcgcc gcacgtagta cccggcgatg
     3361 gcggtggtga cagcggcggt gcagagtgcg acgggtccct gattgaccac cggcggcatc
     3421 cacgcagcga ggtcgatgcg cgcgggagcc ggcccgccgc tcgtccacca gggcgggcgc
     3481 agccgtgtga ggtagtcacg gtccactgtg ccgggatcgg ccgtgctcgt gctcatgtcg
     3541 tgctccggtg ccgcacggtg tggtcgatcc gggcctgcct gcgggcggtc gcggcgtaga
     3601 actgccgtac cgcgtccggg tggaagtccg agaggggacg ggcctcgggc aggaacccgc
     3661 tgcctccctc gcctcggacc gtcagcgcgc tgtcctcacc ctcagtggga cgcaccttcg
     3721 ggctgatgta gtcgatggcg aagttgtacc ggctgtggtc ggtggtgttg gcacccgaac
     3781 agtggaccat cgccaggtgg tgcgccgagc actgtccggc ggtcagcacc acggcgacgg
     3841 acgacgattc gtcgacctcc acagccactt cctcgccgcg catgatgtcc tcgatgtggg
     3901 tgccgcccca gcggtgggcc agggcgccct gggcatggga accgcgggaa tagcgcatcg
     3961 tcccgttggc tgcggtggtg tcggtgagcg ctacccatac ccgtacggca tgctcctggt
     4021 aaccgttcag cccgaggtag accgcgtcct ggtgccaggc gagcgaacct ccgctgtgcg
     4081 cgggcctggt gaacaggttc gtggaccaca ccatgaggtc gggacccagc agcgactccg
     4141 ccaggccgag gagtgccgga tggtggacga ggcggtcggc ccaggtcgcg accagatgaa
     4201 tcttggggaa catcgcgtac tgggccatcg ccccaccgac gctgctgacc gcgcgtaagt
     4261 aggtgcggca gtcggtcagc gcccgtgcgg cttcctcagg ggtgagcgcg tcgaggggaa
     4321 aggcgtagcc gtcagtccgg aagcgatccc gcaggttgtt caccgccgtc ctcatgccgc
     4381 tcctcgactg tcagcgggag gtggcacatc ctcggcagca cgccgcatga cgtcgagcag
     4441 ccgggccgcg tcctcgccct tggcgtccgg cgcctcgggg gaccggagga acgaggccag
     4501 cgccatccgc tgctcctcgg gcatccggcc cttcacctcg tgcagggcgg cggcacgagt
     4561 gcgctggggg aagtacagcg ccttggccgt ctcgaggaag agatccgcgt acttgggttc
     4621 gacgatttcc cggcgtacag cctcggctgt ggcgaccctg atgttgacca tgggttcgca
     4681 gatcagccgc atgacctcgg aatcgaaagt gatcgccacc tcgtcgtcgt cctcgatctc
     4741 gccggacgcg tacatgtcgt agacggtgcc gatgcctgtc atgccgaaga cgtccagctc
     4801 cgcggcgcgc agggcgccca tgctggagga gccgtacatc cgtaccccgc ggtccattgc
     4861 cttcaggatc tccttggggg agatgctgaa gctttggagg aacttcccgt cgacgatgcc
     4921 gatatgagtg ggcgggtcgg cgcgcgccat gagggcatcg atgtcaccac gctcgacggg
     4981 cggcaggaac tcggcgccgg gcaggtgctc ccgtgcctgc tcgacaggca ggctggggcc
     5041 gaggaagacg gataggcgtg gtgcgttcac accgacggtg gtggggatgc tcatgcgttg
     5101 ctctcctgct cgcccgtggt gcgctgctgc cgcttcgcat aggcggagcg gatggtgttc
     5161 agggtgccgt cccacgcttc ccttgcccgg ggaccgatct tgttgcggtc gacggtccag
     5221 gactccgcgc ccggcacgat gacgcgcacg acggtcgcgg ggacggccgg cggcgacagg
     5281 tccacgacga tggcctggtc cagaccgcgg gcgcgaagcc ggtccagcag agtgcggaca
     5341 tcgtccatga cgtcggagct ggggtgcgtg ggcacgtcct ggagccggac cggccgggag
     5401 gacggcttga tcgcccatgc atccggattg gcccggttgc tgcgccgcac gtggtagagc
     5461 gccttctcca ccggctcgcc ggcagcggtg atgtcctcac gcatggcctg gatatccacc
     5521 acacgcgact gcgcgacctc ggctatggcg cgaacgacgg cgacctcggc atccggatgg
     5581 gtaccgattc cgtggtgtga gcgggagaac gagtcgctga tgaactcgga gacgaccgcc
     5641 tggaagctgg ggatgccggt ggccgaggtg atgttcttga cctcgatgtc gatctcggcc
     5701 gcatggaact tgtccatgaa gaactgggcg cgctccggca gtgagtccgg gtcgacgctg
     5761 gggtggaggt cctgtgccca ggcgctgatg gccgtgccga tgggcgtgcc gtcctcctgg
     5821 gcggcgaagc cggccagccg gttggagacc aggtcggcca tcgtccagtc gtcgcgctcg
     5881 atgacctcgc acagggcgtg acagatggcc tcctccagcg agttgccgga tgcgatgcca
     5941 ttggtggtgg acacggggta gcagggcacc tcatgaaagt tcaggtagta cccggcgaga
     6001 aactggggga cgagtacggc gcactcgttc agcaggtcga agccctcgac ccagcagatc
     6061 ggggtgtcca gtgtgtaggc gcgatgaaac tcgaagttgc agctgcgcgg gtccagcacc
     6121 cggcggccgg aagcctccag ctccgtgtac gaggcgaccg cgaccggacg catgggcagt
     6181 ccggctgcga atcgttcgac ggcttccatg accgccgagg tcttggcgtc gatctcggtg
     6241 gcgcccttgc cgttgtagac ggagatgatg tcgaaggagc ggggggagat cgcgttgtag
     6301 acggggatgc cgacgcggtc caggccggtg atgttggcga cccgggtgac acccaccctc
     6361 cgcaggtgcg gcgcgatgcg gcggtaggtg gtctcggacg tgtattcccg gtgcggtccg
     6421 ttcccggtga tcttcgggac gctctggcgc agtttcactg gtgctccttg cgtggtggta
     6481 tcggaatcag gccgcggcgg agggtgcgac gtgcgacgtc ccgtccccga agtaccggta
     6541 gtcaaggttg acttgctgcc ccgcccgtac ggggaccggc tcgggaaacg cccagaccgc
     6601 cgtgtaccag tgactgcggg agcagcccat ccagggggcg gtggacagct gggtggtggg
     6661 gccgagtcgc gcggtgaagt gaacggtgac gccattggcc acaccctcgc cattggcggt
     6721 gagggtgcac gcggtttcca gctgccgggg tgcgtcaccc aacaggtcga cctcgtacaa
     6781 ctcgcccggc gcggacagga actcccactc ctgcaccgtc tccggccgct cgtagaagcc
     6841 gatcgaacgc cttgactcac tctcggccat cggcccgaag tcgatgccgt acatgtcctt
     6901 ccagcgggtg acatgctcgt cggagacacg gtgctggtcc agcagggcgt ccgggatgcg
     6961 ggtgagcgtc gcataggccg tcagggcgcc gggtaccagc cggggcgagt cggtcagcag
     7021 gcggcggcgg gcatcgtgca gcgtctccca gatctgcata tcgagtgcct cgttgccgac
     7081 aatgtcggtg agcagcacgt cggcgggctc gggcagctcc agttgcggcg accaaccgcg
     7141 gatgaattcg atgcggtctg cgacgccgtt gcgctcggcg atactgcgtg cgaggtgcac
     7201 catgccggcg ggttccaccg cgtagacctt gcgggcaccg gcctgtgcgg cggtgatggc
     7261 aaggatcccg gatcctgtac ccagatcgag tacgacgtcg ccctcgcgaa cggtctcccg
     7321 cacgccttgc tggaaggcgg tcttgcgcac cggatcatcc agcatcgcaa tgtggacgag
     7381 cgcggcgtcg tagccgcctt tcgggaaggg ctgactgctg aagccctcca ccggatcgga
     7441 acagagcacg ccggcttggt ggagggccag tacggtggcc agggcctgct cggtggcgcg
     7501 cggccccttg agacgcgcgg agagcagcgt cagggcctga ccgatggtgc gtggagtgtg
     7561 gaagaggtcg agcagcccga gcgcggactg gcccagcttg agcacccggc cttcgaagtg
     7621 gatcttcacc tcgttactgg tgtcgacctc ggcgacaaag gacggcgccc ggtagagaac
     7681 cgtctgtggt gagagcttgg tcatgtctgg gatcactgtc cttctgctcg cgcggcgtgg
     7741 gcggctgcct tgaccagggc cgcagagatg acgggtctga agtcgccgag ggaaccggtt
     7801 tcctggtgtc cttccgtcag ggagacaccg tcctggggct cgaccaggtg gtatccgtcg
     7861 atccggagct gctcggcgtt tcgacgcacc gcgggcttgg accacatcgc ggcgttcatg
     7921 acgggcgcga tgaccacggg gcagtcagcg gccaggagtg tggaggtcag cacgtcgtcc
     7981 gcgatgccat gggctgcctt ggccaggaag ttcgccgtcg ccgggagcac gaccaacacg
     8041 tccgcccacg ctcccagggc gacatgggcg gcgccgatgc cccgatggtc ctcccagtcc
     8101 gtgaccggtc gatggccggt gaccgtctcg atcatgcgag gtcccatgag gtcctgggcc
     8161 tggcgcgtca tgatggtgcg gacctcccgc acccccacga cgccacgcag ccatgcgttc
     8221 acatgcggta cggcgatggc ggagaacgaa ccgcacacgc cccacaggag cttcaccctg
     8281 gacagcgcct gctgtatctc cggtacctca gcggtctctt tcatgcagtg gtcacccttc
     8341 ggtacccgac ggcggcgagg atttcgggca atacccggtc ggcacgacgg aggagcgcga
     8401 gtgcgcctgg ctggtcggat gccgcccatg cacgcagtgc ggcatggtcc aggacgcagg
     8461 aggccgttgc cgaggccagc cgcgccagct cacacggcgt cagtgaggcg tcgcgtgctt
     8521 cctcgtatcc ggccacggcg accttcgcgc agcctgcctt cgcacccgta tcgccggtac
     8581 cggccgccga ctggacgagg tcgcggagca gataggccaa gtcgcccatg gggtctccga
     8641 cgcctgcctc acgccagccg agcacgcggg gcacgggccc tgggacgcat gacgccgtcg
     8701 aaagccgccc gtgcaccagc gtcgaggccg gcgcaggcgt ggtaccgggg ccggtgcacg
     8761 gcggagagct gtccggacgg ccggagagag cagtacccgg cggtacggtg cgtgccagca
     8821 acgaacgggc ttcctggatg ccggatgcca ccgcaggttc cgcgtcgagc caggccgcgc
     8881 gccggcgtac gggcagcgcc tcgccctccg tcgacacggc gtgcagatgg gcgaggaacg
     8941 cgcccagatg acggaacgcc ccctgcaccc aggatcgcgc acacccgtcc ccggtgaaca
     9001 cgacgtcgct gagcagtgcg ggcgtcggca cctcggcgtg cacagatgtg cacgcgtcgg
     9061 cgagggtggg catgaccgcg tacggggcag ccggggtgac ggccaccgac cgtgcgaccg
     9121 cgccgagtgc ctctgcgtcc agataggccg gcgaggccgc acgtaaggac tcgccccaac
     9181 gaaaaccgtc gtcggtccgg atgcagaccc tggtcaggaa cggtcccggc agatgacgga
     9241 ccacctgcct cttggccgct ccctttccgc tgcggtcgct cccggaggtt cccccggtct
     9301 cctgggtgct catatggagg tcgaggggcg ggcgttgaga taggggcgcg caggctcgat
     9361 gccctccgcg cggtaccgct cccggatggc accgaggcgg ccggcagtcc cggtgcggcc
     9421 ctcctgccag gcggtcacca ggccctcggc cgcgagcaga caacggtgct gtccgaaact
     9481 catgaggcgg cccccgtact ggtcgggttc gtcggcgatc caccagcccc gggccagttc
     9541 gagtgcgaag cacggtccgg cgtcccggag tcgggactcg tgatcgcgat ggactgccgc
     9601 gagcgcggcc cggtgccgct cccagtcgtg ccggtagaca tagagcacca gcgggtcgca
     9661 gcgctcgtac ccttccgggt tgttggccga tttgatctgg taggggacac ccagcccgca
     9721 cagcagcccg gtcagggacc tcagcagggt cgccccgctc cgcgggtcgc gaggcgcgaa
     9781 gtacagccgg acgacgggaa gttcaccgtg gctcggcatg ccgtgatcgg atacggccag
     9841 ataccagccc gggtacaggt aaggacgtcc ggagggcatg accaccgaca cctgctgccc
     9901 gggggagagc gatgtgcctt cctgggacgg cacgatctgc tcctcggtcg ccgtcagggt
     9961 cacgccgtcc ttcaggacgg ttacgctccc gtcagcccgc ccggtgacca cccagccggg
    10021 ctcggggtat ccaacggcct ggttggcgac ggagagcagt gcgcccacct cagggtcctc
    10081 ccgccgggtg gtgccgagga ccacgggggc cccgtcgatc agccagcggg cggcccgggc
    10141 atcgccggcg tagtagctca ggtacaggaa gcgccacagg tgggcgagca cgggcagagt
    10201 gcccggctct gtctccaccc cagcagcagg ggacaggtca ccccactccc ggtgacggaa
    10261 agttgcctgg tccaggacct ctatgtcctc cgccatgctg gcgaacactg cgtcgtatct
    10321 gctcatgcgc ggctgctccg ccccttcgac ggcaggaata gttcggcgat gccctgcggg
    10381 ttcttcagca gctggcgccc gacgaacaga cacaggtgcc cgatcctgcc cagcgagccg
    10441 atctgttcca ggcgtccggc cgcgtgcatc agggcgaaca gcccggcgta gcggaacaca
    10501 gcgatgtgct gctcctcgga gagcggagcc acgtgttcgt aggcggtgat gaagagaccg
    10561 gcgttacgtc gcacggtcgt ccatgcggct gcggaagcga gctgttccgg ggtgtcgcgc
    10621 acggtctgga gccactgcac gagcaattgc cccaccaccg tgccgacatc gagcagggga
    10681 tcgccgtacc cggccatctc ccagtcgacc agggcgacct ccggacgatc gtcggcgttc
    10741 tcccgtacga ggatgttgtc gtcccgcagg tcgaagtgga ccaaggagga gggctgccag
    10801 gagcgccgca gcatgtcgac ctcggtgtcg acggcctgca tcgccgcaac gtacgccggg
    10861 tagtccatgc ctggcccccc caccagctgc tcaggggtca gcacggcgaa tgaggcgaag
    10921 gggaaaccga aactccgcag gccggaggcg tcccgtccgt gcgtgtccgg tacgggtgtc
    10981 cggtgaatac cggcaaccac gctggccatc gccacgagca cggacaccgg aatatccggc
    11041 gaactctgca ccagctcccg aagtgaggcg aaaccgacct tcccctccat gacgagggtt
    11101 ccactctctg ggtcggtcgc gacgagccgc ggaatagcac gttcggagac gacggggagt
    11161 ccggcgacag gcaccagacg caacatcgcc tcctcattcc gaaatgccgc atcaatcgca
    11221 acccctgcgg cattatccat ttccttcagg aacaaggagg tgccgtcctc gaaacgcagc
    11281 atcaccgcgc gactgcgtgc gacgaattcc tgggcgtcaa tgattcgccc gtgatccacg
    11341 ccgagcgagg ccaaccagga acggatccgg cgccgactga caccggaccc gtccggcagc
    11401 gctccggtca agggcgagga tggtgcacga cccactcgat caggccgacg gtgcaccgga
    11461 ccggccttct gctcggaagc gctgcttgcc attgtctaac tcagcagtgg taagccacgg
    11521 tggcgatggc ggccatgacg ctgccttgcg cctcctcgtc cggcgatatg ccggccttct
    11581 cctccaggaa tgcctgcagg tcctcggggc tgactcccgc cagctcctcc agggccttct
    11641 cgccggcggc cgggtcgata acggcgcgct gctcgtccgt catcgccagt tcggcttcct
    11701 tgattttgct gaccaggtcg ctgaacgcga cctcgtccac ctgagctgct gtcgtggttt
    11761 cagacat
//
