BGC0002560: thiostreptamide S4 biosynthetic gene cluster from Streptomyces sp. NRRL S-4
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Location: 86,914 - 98,680 nt. (total: 11,767 nt).
This entry is originally from NCBI GenBank LGKJ01000112.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002560
Short description thiostreptamide S4 biosynthetic gene cluster from Streptomyces sp. NRRL S-4
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
LGKJ01000112.1
86914 - 98680
via Heterologous expression
Compounds
  • thiostreptamide S4
Species Streptomyces sp. NRRL S-4 [taxonomy]
References
Chemical products information
thiostreptamide S4 Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADK82_11800
  • KPC82018.1
 86914 - 87924 (-) FMN-linked alkanal monooxygenase
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    • ADK82_11805
    • KPC82467.1
    		 88056 - 88835 (-) hypothetical protein
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      • ADK82_11815
      • KPC82019.1
      		 89634 - 90449 (-) hypothetical protein
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        • ADK82_11825
        • KPC82020.1
        		 91285 - 92007 (-) hypothetical protein
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          • ADK82_11830
          • KPC82021.1
          		 92004 - 93371 (-) hypothetical protein
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            • ADK82_11835
            • KPC82468.1
            		 93400 - 94518 (-) hypothetical protein
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              • ADK82_11845
              • KPC82022.1
              		 95234 - 96226 (-) hypothetical protein
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                • ADK82_11850
                • KPC82023.1
                		 96223 - 97131 (-) hypothetical protein
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                  • ADK82_11855
                  • KPC82024.1
                  		 97236 - 98099 (-) hypothetical protein
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                    • ADK82_11860
                    • KPC82025.1
                    		 98414 - 98653 (-) hypothetical protein
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                      Biosynthesis information
                      Annotation changelog

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-10-07
                      Update chemical activity to schema version 2.11
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-10-07
                      Added chemical structures for compounds: thiostreptamide S4.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-10-07
                      Added NPAtlas links to compounds: thiostreptamide S4.
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Entry added
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-09-15
                      Updated bioactivity data
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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