LOCUS       BGC0002561             17947 bp    DNA     linear   BCT 15-JUL-2019
DEFINITION  Streptomyces sp. strain NA04227 arabinose ABC transporter permease,
            hypothetical protein, and RNA polymerase subunit sigma genes,
            complete cds; spz gene cluster, complete sequence; and YdcF family
            protein and N-acetyltransferase genes, complete cds.
ACCESSION   BGC0002561
VERSION     BGC0002561
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:00:18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17947
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..480
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /note="putative phenazine biosynthesis protein"
                     /product="SpzB"
                     /protein_id="QDJ94207.1"
                     /sec_met_domain="phzB (E-value: 1.6e-71, bitscore: 231.0,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPASAEEIAGNREANRRIVEQYMNTRGQDRLRRHELFTEDGQG
                     GLWTTETGEPIVISGRDRLGEHAVWSLKCFPDWAWVDIEIFDTQDPNQFWVECNGRGKI
                     IFPGYEEGFYENHFIHYFRFEDGKIRLQREFMNPCQQFKALGIEVPRVKREGIPT"
     misc_feature    1..17947
                     /note="spz gene cluster"
     protocluster    1..17947
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[16711:17947]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16712..17947
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..17947
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /detection_rules="phzB"
                     /kind="neighbouring"
                     /product="T3PKS"
                     /product="phenazine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..17947
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002561"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17947
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T3PKS"
                     /product="phenazine"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /rules="phzB"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..10480
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[0:480]"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..480
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="2"
     cand_cluster    1..10480
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="phzB"
                     /kind="single"
                     /product="phenazine"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             490..1761
                     /codon_start=1
                     /note="3-deoxy-D-arabino-heptulosonate 7-phosphate
                     synthase"
                     /product="SpzC"
                     /protein_id="QDJ94208.1"
                     /transl_table=11
                     /translation="MAARVVIHKSAGEEFVNNSGFLDRGLPAAQQPEWEHPHQVAQVRN
                     VLSATDALVSPEQILALRESLADVARGEGLVLQAGDCAEHPDECGEAHIAAKAGLVNRL
                     AEALGEQPGVPVLRVGRIAGQFAKPRSKPTEEIDGLVLPAYRGHIVNAPEVDEHSRRPD
                     PLRMLMCFMASREAMQHLGWRQGGDWATRAPEDRVWSSHEALLIDYEEPQLRKLDDGRL
                     WLSSTHWPWIGERTRQLDGAHVELLSKVVNPVACKVGPTMTPDELLELCARLDPEREPG
                     RLTLIVRMGAEQIGERLPALVRAVRDNGHPVLWFIDPMHGNTVKLADGTKSRDVTTVSD
                     EVRQFLSCLAEAGVRAHGLHLEASPYAVGECFGGFGPRSAPGTHGTGMPSLCDPRLDPD
                     QAAEVVAAWSDVQAAPAASALSKG"
     misc_feature    553..555
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             1710..2390
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 253.9; E-value: 2.3e-77)"
                     /gene_kind="biosynthetic-additional"
                     /note="2,3-dihydro-3-hydroxy-anthranilate synthase"
                     /product="SpzD"
                     /protein_id="QDJ94209.1"
                     /transl_table=11
                     /translation="MVGRPGRTRSFRSQQGVEDLTTSLRVEPYDLPSREDLPVGPVDWQ
                     VSPERAVLLIHDMQTYFLEPLGQDMRSRLVDNAAALRKVCVERGMRVAYTAQPGRMTEQ
                     DRGLLRDFWGPGMTSSEADRSIVAELAPQASDWNLVKWRYSAFFRTDLLQRMREEGRDQ
                     LLIAGVYGHVGILTTALEAYTNDIQVFLAADAIGDFSAEHHRMTLEHAARVCAKVSDVD
                     GLVA"
     CDS             2387..4312
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 301.3; E-value:
                     2.6e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="2-amino-2-desoxy-isochorismate synthase"
                     /product="SpzE"
                     /protein_id="QDJ94210.1"
                     /transl_table=11
                     /translation="MSIDNEPTGAHGHRPADLLQAVLDGSVRDFALICRDGEHGRRVQV
                     LTGEVGHHESLDALDLGARGGASAGAGADGSDVLVVVPYRQLAERGYPAPDDGTPLIAM
                     TVQQQEHHAVASVLDRLPQHAVRLANGRFEPDDAAYAQTVKSVIADEIGTGEGANFVIK
                     RTYLADITGYRPEQAFSVFGELLSRERGAYWTFLVQTRDATLIGASPERHVSLADGVAT
                     MNPISGTYRYPDGGPTLAGLTEFLADRKEAEELYMVVDEELKMMCRVCEPGTVQVNGPH
                     LKEMAKVAHTEYHITGTSGADIPEVLRATMFAPTVTGSPVESAARVIQRYEPEGRGYYS
                     GIIGLAGTDEQGRRTLDSAILIRTAVLEPTGKVAISVGSTLVRHSDPQGEVAETRAKAK
                     ALLEAFGERAQGSSPAQDPRILDSLKSRNDGIAGFWVGQDAGRGVTSSLLEGRKALVID
                     AEDTFTSMLDHQLRALGLSVTVRRFDETFEVRDHDVVLVGPGPGDPLATEHPKIAALDK
                     VVGELLAERHPFVAVCLSHQVLSRRLGLPLVRRERPNQGTQRQIDLFGSPERVGFYNTF
                     EARSATANWTGPDGEQVEISRNPDTDEVHALRGDRFASLQFHAESLLTVDGPRILTDMF
                     EGVLAP"
     CDS             4309..5478
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) thio_amide"
                     /gene_kind="biosynthetic-additional"
                     /note="trans-2,3-dihydro-3-hydroxyanthranilate isomerase"
                     /product="SpzF"
                     /protein_id="QDJ94211.1"
                     /sec_met_domain="thio_amide (E-value: 6.8e-13, bitscore:
                     38.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMEIAWWDLDGSPATVESLEKHLSEDGVAHNWQSVEGLREKFWI
                     ADPEGKRWGAVMVWDQERPADLPENLAAALIGAPISHRDRFDVQATVRGEGLLRVRDRA
                     HRYVVVDAFATEVLRGNPVAVFWDADDLTSDQMQRIAKEMNLSESVFLLSPTVEDADVR
                     TRIFTPVNELPFAGHPLLGTAVAVGLDRRADHLRFETKMGVVPFEVDRTPAEQFGGGVA
                     YISMEQPIPVHEPYEHAEALLEALGIDSSTLPVEIYRNGPRHVFVGLPDADALAALHPD
                     HRALSAFPDMAANCFAPEGERWQTRMFSPAYGVVEDAATGSAAGPLAIHLARHGLVEYG
                     KTIEIHQGVQLGRRAVMFAEATLKDDSTELDRVRVSGHGTVASEGTIHI"
     CDS             5500..6144
                     /codon_start=1
                     /note="FMN-dependent oxidase"
                     /product="SpzG"
                     /protein_id="QDJ94212.1"
                     /transl_table=11
                     /translation="MSSVYESLTGSVDLPFPEYDNPPPSPMGLAKQWTDHAREVGVREP
                     MSLALSTVDGEGRLSSRICQIIEVAEGGLLFTTHSTSRKGREIAESGRATGLFYWRETG
                     QQLCVSGPVVQLDDAAHDKWWMARDHRLHTMTVASRQSDVLDDPAALLTEERRQAEIAG
                     GGPLPRPDRFVAYQLQPESVEFWNAAASRLHRRLRYEKQDGGTWNVVKLEP"
     CDS             6256..7878
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 424.9; E-value: 8.3e-129)"
                     /gene_kind="biosynthetic-additional"
                     /note="monooxygenase"
                     /product="SpzQ1"
                     /protein_id="QDJ94213.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.8e-18, bitscore:
                     54.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKENQLDSIVIGAGFAGIYMLHKLRNELGLNVRSFERGSGIGG
                     TWHWNRYPGAAADVDSIAYRYSFDSALIKEWNWKTRYAPQAEILAYLEHVVDRYELRED
                     IQLNTTVEALTFDEATSLWTVRTDDGEEYTARYVVGALGPLSTANFPDIEGRESFAGTQ
                     VHTGAWPQELDITGKKVGVIGTGSTGTQFIGAAAKIADHLTVFQRSAQYVVPAGDGPLS
                     EEFLEDYRENHEQFWKQVFNSRVACGFQEAEISAMAVSAEERERKFQESWDAGNGFNFM
                     FGTFADIAFNPESNEAAASFIRSKIKEIVRDPETARKLMPTDYYAKRPICNTGYYESYN
                     RDNVALISTKENPIVKITPKGVQTEDGTEHEVDVLVFATGYEAMQGSYNKIDIRGAGGR
                     SLKEHWGEAPSSYLGVATNGFPNLFTVFGPNSVFSNLPPALQTQVEWISDTIGEARKRG
                     VGRVEATAAAEEEWTVMCREMAQHSLFAQTDSWIFGSNIPGKERRTLFYFGGIAAYREK
                     LKEIVSADYEGFTLDGEAAPSAV"
     CDS             8173..8556
                     /codon_start=1
                     /note="monooxygenase"
                     /product="SpzQ2"
                     /protein_id="QDJ94214.1"
                     /transl_table=11
                     /translation="MSQWMCGPENGSVASFGRMTETVIRAGDDVATVINVFETQPDKQQ
                     ELVGVLNEGLDKVVRHRPGFVSATILASKDGSKVVNYAQWRSPADAQATFGDPAVQEYG
                     KKAAALGTPAPGVYSVDSVTLAP"
     CDS             8668..9870
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 276.1; E-value: 8.9e-84)"
                     /gene_kind="other"
                     /note="flavin dependent hydroxylase"
                     /product="SpzS"
                     /protein_id="QDJ94215.1"
                     /transl_table=11
                     /translation="MTEAATPGIVIAGAGIGGLATALALHARGLSVTLIEEAKEIRPLG
                     VGINIQPAAIGELTALGLGEKLAATGIATREHRYLDHKGNTLWTEPRGIAAGNDFPQYS
                     IHRGELQMMLLEAVRERLGDDAIRTNTRVRGFDQDADGVRVHLSSPVDGDSTIEASVLL
                     GADGIHSPIRAQLHPEGSPLRKTAVRMWRGLAELPEFIDGRTMIIASDDNANRLVAYPC
                     SRPHADQGKVLFNWVCLAADPKWDGEVQLTPGRIEDVLEHFSDWDFGWLDVPATLKSSP
                     QVMHHIMVDRDPLETWGEGRVTLLGDSAHPMYPIGANGGTQAILDGITLARELAEAGDD
                     IPAALQRYESVRRPATNEIVTANRKMDRSERDLAGTKGDVADELETITTDYRDVVEKSH
                     A"
     CDS             10021..11010
                     /codon_start=1
                     /note="prenyltransferase"
                     /product="SpzP"
                     /protein_id="QDJ94216.1"
                     /transl_table=11
                     /translation="MSATAVSAREKLSRILTDTSEDDPQRPPLGTQLKYYFYIRRPEFL
                     PGHILIGLAPAMLAATSWDEFTSVNAVVAILFAIVNMQLADQINALADRWEDAANKSRL
                     ATAVYGLGVKRVVGDVIVTSLVYIAMAVFLAAKTGHWDLLLIVAAGWVVGMQYSLPPWH
                     LKSAGVGQLFGLYLWVWIPMLFVLRAFDNELQWTNVVATAALTVILVALFTTNQIEDFF
                     DDEEFDVRTYVRALGIKKTLAVQSTILCVASLVIVAAVWQNSGFNWGMIPFLAAWLVCQ
                     GYMYSLSKAAGAPIENVVDSVKKKSLVGPYLSMLMSSMTTVVGIGVLA"
     CDS             11273..12301
                     /codon_start=1
                     /note="mevalonate kinase"
                     /product="SpzH"
                     /protein_id="QDJ94217.1"
                     /transl_table=11
                     /translation="MTSPTSAQGLPRHFGTRRIGIGRAHGKIILIGEHAAVYGAPALAG
                     PVPQLPVTASVAQLPDAEGGSGEASFSVTSAVTGTVAMKATDGLQRLVVEFKERTEVTD
                     QQHIDVVVDCEIPLGRGLGSSAACARAIVLGLADLYDRELDEDTVFELVQIAENVAHGR
                     ASGVDALATGARAPFLFSAGTADTLPTARETPIGLDGFLVIADSGEAGGTREAVEMLRA
                     SFGREEGSQERFLTRANELTGAAVRDLAEGRVAELGESFTAYHELLRAAALSTQRIDAL
                     VEAALAAGSHGAKISGGGLGGCMIALADGTDQARHIETRLREAGAARTWTTPLKRSTDR
                     AS"
     CDS             12387..13400
                     /codon_start=1
                     /note="mevalonate diphosphate decarboxylase"
                     /product="SpzI"
                     /protein_id="QDJ94218.1"
                     /transl_table=11
                     /translation="MQEPVTEGGATAVAQPNIALIKYWGKRDEQLFIPMTSSLSMTLDI
                     FRTTTTVRLGTEADVDSVALNGKAASGEAERRVLVFLDLVRELAGRKERAVVDTHNEAP
                     TGAGVASSASGFAALALAASAAYGLDLDARALSRLARRGSGSASRSVYGGFVQWHKGQG
                     EGADADLSSYAEPVPVGDIDPALVIALVDGGPKSVSSRAAMRSTVDTSPLYQGWADSSE
                     GDLTEMRRALSRGDFEAVGEIAERNALGMHATMLAARPAVRYLSPATVTVLDRVLQLRA
                     DGIPAYATMDAGPNVKVLCRRADADRVAEAVREAMTAGSVVVAGSGPGARLLTEGG"
     CDS             13400..14572
                     /codon_start=1
                     /note="phosphomevalonate kinase"
                     /product="SpzJ"
                     /protein_id="QDJ94219.1"
                     /transl_table=11
                     /translation="MPAQQAVTRRAPGKLFLLGEYAVLEPGTPSILMAVDRYLGVTVSV
                     PEEADGPDGPGDGADIVVVTELLPEPARFTRQLDGEPLWCGPAEQEQSARAALAHILSV
                     VGVLDALLAEHGRKAPAFRLSVSSELHEGGTKFGLGSSGAVTVASVAALAAYYGLDLTR
                     DERFRLALLATGRLNASSSCGDLAASTFGGWITYRAPDRAEVVAMARQHGIGESLRAHW
                     PGYEVRPLPSPPGLSTEIGWTGTPASTDALVSGLGRRKWRGTAAHRAFVAATDECVRAS
                     VKAIEQGDRDELLDRIRSARTTLAQLDEEVGLGVFTSRLTALCEVAEELGGAAKPSGAG
                     GGDCGIALLPVEREPEIRQLRTRWAAAGVRHLPLRPAEVSTTERNARNDR"
     CDS             14562..15653
                     /codon_start=1
                     /note="isopentenyl diphosphate isomerase"
                     /product="SpzK"
                     /protein_id="QDJ94220.1"
                     /transl_table=11
                     /translation="MIAERKDDHVRLTVEQQRRLSGQNEFDDVRFVHHALAGIDRDDVS
                     LATSFAGIDWQAPIYINAMTGGSVNTGVINRDLAIAARETGVAIATGSVSAFFKDPSSA
                     ETFSVMRREYPGGFIMGNVNLNATADQARKAVELLEANALQIHLNTIQETAMPEGDREF
                     SHWQSRIEEIVTALDVPVIVKEVGFGLSRETIATLQKLGVHVADVGGRGGTNFAQVEND
                     RRDVADFGYLNDWGLSTAACLLDAQDAGIPVLASGGVRNPLDVARSLALGASAVGASGG
                     FLRSLMDGGVDALVKHINTWLDHLSAIMTALGARTPAELAHCDVLIKGELRDFCADRGI
                     ETGPLSRRSTRLAATEQTTGSAR"
     CDS             15650..16708
                     /codon_start=1
                     /note="3-hydroxy-3-methylglutaryl CoA reductase"
                     /product="SpzL"
                     /protein_id="QDJ94221.1"
                     /transl_table=11
                     /translation="MSDITTAGVPMKWVGPMRISGNVATTEAEVPLATYETPLWPSVGR
                     GAKISMLTEKGIVATLVDERMTRSVLVEAEDAQTAYAAAQQLELRFEDLQKVVRTCSRF
                     AELVKVRHEIAANLMFIRFEFTTGDASGHNMATLAADALLTHILQTIPGLSYSSISGNY
                     CTDKKATAINGILGRGKNVVTELLVPREIVESRLHTTADKVAKLNVRKNLIGTLLAGGI
                     RSANAHFANMLLGFYLATGQDAANIVEGSQGVTFAEDRDGDLYFSCTLPNLIVGTVGNG
                     KGIDFVEENLIRLGCREEREPGENARRLAVLCAATVLCGELSLLAAQTNPGELMRAHVQ
                     FERKNSSTQAGV"
     CDS             16712..17947
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:hydroxymethylglutaryl-CoA synthase (Score: 470.8;
                     E-value: 5.2e-143)"
                     /gene_kind="biosynthetic"
                     /note="3-hydroxy-3-methylglutaryl CoA synthase"
                     /product="SpzM"
                     /protein_id="QDJ94222.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.3e-09,
                     bitscore: 27.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSANGNHTQGGNNGSNATGGTGGAIAVGIEDLSFATTEYVLPHTE
                     LAAYNGTEIGKYHLGIGQQSMSVPAADEDIVTMAAAAAAPIVARHGAGRIRTVILATES
                     SIDQAKAAGVYAHSLLGLPAATRVVELKQACYGATAALQFAMGLVYRNPSEQVLVIASD
                     VSKYDLDSPGEATQGAAAAAILVGANPSLLRIEPASGLFTADVMDFWRPNYRDTALVDG
                     QESISAYLQAVEGSWKDYSEQGGRSLEDFAAFCYHQPFTKMAYKAHRHLLHYCGHPVEN
                     DEVARVLEPTTTYNSVVGNSYTASLYLGLAALLDSDADLTDRAIGLLSYGSGSVAEFFA
                     ATVVPGYRAHLRTKAHREAIDRRKPIDHATYRELHQRSFPTDGGDYPVPAQTSGPYRFS
                     ALSGHKRIYEPR"
ORIGIN
        1 atgagcgccc ccgcgtccgc cgaagaaatt gccggcaacc gcgaagcgaa ccgacgtatc
       61 gtcgagcagt acatgaacac ccgtggtcag gaccgcctgc gccgccacga gctgttcacc
      121 gaggacggcc agggtggtct gtggaccacc gagaccggcg agcccatcgt gatcagtggc
      181 cgcgaccgtc tcggtgagca cgccgtctgg tccctgaagt gcttccccga ctgggcctgg
      241 gtcgacatcg agatcttcga cacccaggac cccaaccagt tctgggtcga gtgcaacggc
      301 cgcggaaaga tcattttccc cggctacgag gaggggttct acgagaacca cttcatccac
      361 tacttccgtt tcgaggacgg aaagatccgg ctccagcgtg aattcatgaa cccgtgccag
      421 cagttcaagg ccctcggcat cgaggtgccg cgcgtgaagc gtgaaggcat acccacctga
      481 gccgggcccg tggctgcacg ggtcgtcatt cacaagtctg cgggggaaga gttcgtgaat
      541 aattcagggt tcttagaccg aggccttccc gctgcccagc agccggaatg ggagcatccg
      601 catcaggttg ctcaggtccg caatgttctg tcggcgaccg acgctctcgt cagtcccgaa
      661 cagatcctcg cgttgcggga gtcgctcgcc gatgtcgcca ggggtgaggg tctggttctc
      721 caggccggcg actgtgccga gcacccggac gagtgcggcg aagcgcacat cgccgcgaag
      781 gccggtctcg tcaaccggct cgccgaggca ctcggcgagc agccgggggt tccggtcctg
      841 cgggtgggcc ggatcgccgg acagttcgcg aagcctcgct ccaagcccac cgaagagatc
      901 gacggccttg tgctgcccgc ctaccggggg cacatcgtca acgcccccga ggtcgacgag
      961 cacagccgtc ggcccgatcc gctgcgcatg ctgatgtgct tcatggcctc gcgcgaggcg
     1021 atgcagcacc tcggctggcg gcagggcggc gactgggcca ctcgcgcgcc cgaggaccgc
     1081 gtgtggtcca gccacgaggc cctgctcatc gactacgagg agccgcagct ccgcaagctc
     1141 gacgacggca ggctctggct gagctccacc cactggccgt ggatcggtga gcgcacccgt
     1201 caactcgacg gtgcccacgt ggagttgctg tccaaggtcg tcaacccggt cgcctgcaag
     1261 gtcggcccca cgatgacccc cgacgagctg ctcgaactgt gtgcccgtct ggacccggag
     1321 cgcgagcccg gtcgcctgac gctcatcgtg cggatgggcg ccgagcagat cggcgagcga
     1381 cttccggccc tcgtccgcgc cgtccgggac aacggccacc cggtgctgtg gttcatcgat
     1441 ccgatgcacg gcaacacggt gaagcttgcg gacggcacca agagccgtga tgtgacgacc
     1501 gtctccgacg aggtgcggca gttcctgtcg tgtctggccg aggcgggcgt cagggcgcac
     1561 gggctgcacc tggaagcgag cccgtacgcg gtcggcgagt gcttcggcgg tttcggaccg
     1621 cgctcggcgc ccggcacgca cggaaccggc atgccgagtc tgtgcgaccc gcggctggac
     1681 ccggaccagg ccgccgaggt cgtggcggcg tggtcggacg tccaggccgc acccgcagct
     1741 tccgctctca gcaaggggta gaggacttga ccacatctct tcgcgtcgaa ccgtacgacc
     1801 ttcccagcag ggaagatctc ccggtcggcc cggtcgactg gcaggtgagc ccggagcggg
     1861 ccgtcctgct catccacgac atgcagacct acttcctgga gccgctgggc caggacatgc
     1921 gcagccgcct ggtcgacaac gcggccgcac tgcgcaaggt ctgcgtggag cgggggatgc
     1981 gggtcgccta caccgctcag cccggtcgta tgaccgaaca ggaccgcgga ctgctccgcg
     2041 acttctgggg accggggatg accagctccg aggccgaccg ctccatcgtg gccgaactgg
     2101 ccccgcaggc ctcggactgg aacctcgtca agtggcgcta cagcgccttc ttccgcaccg
     2161 atctgctcca gcgcatgcgg gaggagggcc gtgaccagct gctcatcgcc ggtgtgtacg
     2221 gacacgtcgg catcctcacc acggcgctgg aggcgtacac caacgacatc caggtcttcc
     2281 tggccgcgga cgccatcggc gacttctcgg ccgagcacca ccggatgacg ctggagcacg
     2341 cggcgcgtgt ctgcgccaag gtctcggacg tggacggact ggtggcatga gcatcgacaa
     2401 cgagccaacc ggggcgcacg gccacagacc ggccgatctc ctccaggccg tactcgacgg
     2461 ctcggtccgg gacttcgcgc tgatctgccg cgacggcgag cacggccgcc gcgtacaggt
     2521 cctcaccggc gaggtcggcc accacgagtc gctcgacgcg ctcgacctcg gagcccgcgg
     2581 cggcgcgtcc gcgggcgccg gggcggacgg cagcgacgta ctggtggtgg tgccctaccg
     2641 ccagctcgcc gagcgcggct accccgcgcc cgacgacggc accccgctca tcgccatgac
     2701 cgtgcagcag caggagcacc acgcggtggc ctcggtcctg gaccggctgc cccagcacgc
     2761 ggtgcggctg gccaacgggc gcttcgagcc cgacgacgcg gcgtacgcgc agaccgtcaa
     2821 gtcggtcatc gccgacgaga taggcaccgg cgagggcgcc aacttcgtca tcaagcgcac
     2881 ctacctcgcc gacatcaccg gctaccgccc cgagcaggcg ttctccgtct tcggcgaact
     2941 cctgtcccgg gagcgcggcg cgtactggac cttcctggtg cagacccgcg acgcgaccct
     3001 gatcggcgcc tcgcccgagc gtcacgtcag cctggccgac ggcgtcgcca ccatgaatcc
     3061 gatcagcggc acctaccgct acccggacgg cggcccgacc ctggccggtc tgaccgagtt
     3121 cctcgccgac cgcaaggagg ccgaggagct gtacatggtg gtggacgagg aactgaagat
     3181 gatgtgccgg gtctgcgagc ccggcacggt gcaggtgaac ggcccgcatc tcaaggagat
     3241 ggcgaaggtc gcgcacaccg agtaccacat caccggaacc tccggcgcgg acatccccga
     3301 ggtgctgcgc gccaccatgt tcgcgcccac cgtcaccggc agcccggtgg agagcgcggc
     3361 ccgcgtgatc cagcgctacg agcccgaggg ccgcggctac tacagcggca tcatcggcct
     3421 ggccggcacc gacgagcagg gccggcgcac cctcgactcc gcgatcctca tccgtaccgc
     3481 cgtcctggag cccaccggca aggtggccat ctcggtcggc tccaccctgg tacgccactc
     3541 cgacccgcag ggcgaggtgg ccgagacccg ggccaaggcg aaggcgctcc tggaggcctt
     3601 cggcgagcgt gcgcagggga gttcacccgc gcaggacccg cggatcctcg actcgctcaa
     3661 gagccgcaac gacggcatcg ccgggttctg ggtcggacag gacgcgggcc gcggcgtcac
     3721 ctcctcgctg ctcgaagggc gcaaggccct ggtgatcgac gccgaggaca ccttcacctc
     3781 gatgctcgac caccagctgc gcgcactggg cctctcggtc accgtgcgcc gcttcgacga
     3841 gaccttcgag gtccgcgacc acgacgtggt cctggtcggc cccggccccg gtgacccgct
     3901 ggccaccgag cacccgaaga tcgccgccct ggacaaggtg gtcggtgaac tcctcgccga
     3961 gcggcacccg ttcgtcgcgg tctgcctcag ccaccaggtc ctgtcccggc ggctcggcct
     4021 gccgctggtc cgccgcgagc gcccgaacca gggcacccag cggcagatcg acctgttcgg
     4081 ttcgccggag cgggtcggct tctacaacac cttcgaggcc cgcagcgcga ccgcgaactg
     4141 gaccggcccg gacggcgagc aggtcgagat cagccgcaac ccggacaccg acgaggtgca
     4201 cgcgctgcgc ggcgaccgat tcgcctcgct gcagttccac gcggagtccc tgctgaccgt
     4261 cgacggtccg cggatcctga ccgacatgtt cgaaggggtg ctcgcaccat gaagatggag
     4321 atcgcctggt gggacctgga cgggtccccc gccaccgtgg agagcctcga aaagcacctg
     4381 agcgaggacg gcgtcgccca caactggcag tccgtggagg gacttcggga gaagttctgg
     4441 atcgccgacc cggagggcaa gcgctggggc gcggtcatgg tctgggacca ggagcgcccg
     4501 gccgacctgc ccgagaacct ggccgccgcg ctcatcggcg ccccgatcag ccaccgggac
     4561 cgcttcgacg tccaggccac cgtccgcggc gagggcctgc tgcgggtccg tgaccgcgcg
     4621 caccgctacg tcgtggtcga cgccttcgcc accgaggtgc tgcgcggcaa cccggtcgcc
     4681 gtgttctggg acgcggacga cctgacctcc gaccagatgc agcgcatcgc caaggagatg
     4741 aacctctccg agtcggtgtt cctgctgtcg ccgaccgtcg aggacgcgga cgtacgcacc
     4801 cgtatcttca cgccggtcaa cgaactcccg ttcgccgggc acccgttgct cggtaccgcc
     4861 gtcgcggtcg gcctcgaccg ccgcgcggac cacctgcgct tcgagaccaa gatgggcgtc
     4921 gtgcccttcg aggtcgaccg cacgcccgcc gagcagttcg gcggcggcgt cgcgtacatc
     4981 tcgatggagc agccgatacc ggtccacgag ccctacgagc acgccgaggc gctgcttgag
     5041 gcactcggca tcgactcctc cacgctgccg gtggagatct accgcaacgg cccccggcac
     5101 gtcttcgtcg gactgcccga cgccgacgcg ctcgccgcgc tgcaccccga ccaccgggcc
     5161 ctgtccgcct tcccggacat ggccgccaac tgcttcgccc ccgagggcga gcgctggcag
     5221 acccggatgt tctcgcccgc ctacggcgtg gtcgaggacg cggccaccgg ctcggcggcc
     5281 ggccccctcg ccatccacct ggcccggcac ggactcgtgg agtacggcaa gaccatcgag
     5341 atccaccagg gtgtccaact cggccgccgc gcggtgatgt tcgccgaggc cacgctgaag
     5401 gacgacagca ccgagctcga ccgggtgcgg gtgagcgggc acggcaccgt cgcctccgaa
     5461 ggcaccatcc acatctgacc ggacctgaac ggaagcgtca tgagcagcgt ctacgagagt
     5521 ctgaccgggt cggtcgacct gcccttcccc gagtacgaca acccgccgcc gagcccgatg
     5581 ggcctggcga agcagtggac ggaccacgcc cgcgaggtgg gtgtgcgcga gcccatgtcg
     5641 ctggccctgt ccaccgtgga cggcgagggc cgcttgtcca gccggatctg ccagatcatc
     5701 gaagtcgccg agggcgggct gctgttcacc acgcacagca ccagccgcaa gggccgcgag
     5761 atcgccgaga gcggccgggc gaccgggttg ttctactggc gcgagacggg ccagcagctg
     5821 tgtgtctcgg gcccggtcgt ccagctcgac gacgccgccc acgacaagtg gtggatggcc
     5881 cgcgaccacc ggctgcacac catgaccgtc gcctcccggc agagcgacgt cctcgacgac
     5941 ccggcggcgc tgctcaccga ggagcgccgc caggccgaga tcgccggcgg cggcccgctg
     6001 ccgcgccccg accggttcgt cgcgtaccaa ctccagccgg aatcggtcga gttctggaac
     6061 gccgccgcct cccgactgca ccgccgcctg cgctacgaga agcaggacgg cggcacctgg
     6121 aacgtcgtca agcttgagcc gtagtcgacg aactccccac gcgaggccgc cttttgaggg
     6181 ggcggccccg cgtccgtcgc gcccgccccg caccgaggca cctctctcct ccaccgcatg
     6241 attcgaaagg ccgagatgtc caagaaagag aaccagctcg actcgattgt catcggtgcc
     6301 ggtttcgccg gcatctacat gctgcacaag ctccgcaacg aactcggcct gaacgtacgg
     6361 tccttcgagc gaggctccgg catcggcggc acctggcact ggaaccgcta cccgggcgcg
     6421 gccgcggacg tcgactccat cgcgtaccgc tactccttcg acagcgcgct gatcaaggag
     6481 tggaactgga agacccgcta cgcgccgcag gcggagatcc tggcctacct ggagcacgtg
     6541 gtcgaccggt acgagctgcg cgaggacatc cagctcaaca ccaccgtcga ggcgctgacc
     6601 ttcgacgagg ccaccagcct gtggacggtg cgcacggacg acggcgagga gtacaccgcc
     6661 cgctacgtgg tcggcgcgct cggcccgctg tcgaccgcca acttccccga catcgagggc
     6721 cgcgagagct tcgcgggcac ccaggtgcac accggcgcct ggccgcagga gctggacatc
     6781 accggcaaga aggtcggcgt gatcggcacc ggttcgaccg gtacccagtt catcggcgcc
     6841 gccgccaaga tcgccgacca cctcacggtc ttccagcgct ccgcgcagta cgtcgtgccc
     6901 gcgggcgacg gaccgctcag cgaggagttc ctggaggact accgcgagaa ccacgagcag
     6961 ttctggaagc aggtcttcaa ctcccgggtc gcctgtggtt tccaggaggc cgagatttcc
     7021 gcgatggcgg tttccgccga ggaacgcgag cggaaattcc aggagagctg ggacgcgggc
     7081 aacggattca atttcatgtt cggcactttc gccgacatcg ccttcaaccc ggagtcgaac
     7141 gaggccgccg cttcgttcat caggtcgaag atcaaggaaa tcgtgcgcga cccggaaacc
     7201 gcgcgcaagc tgatgccgac cgattactac gcgaagcggc cgatctgcaa caccggttac
     7261 tacgagtcct acaaccggga caacgtggcg ctcatctcca ccaaggagaa cccgatcgtc
     7321 aagatcaccc cgaagggtgt gcagaccgag gacggcactg agcacgaggt cgacgtgctc
     7381 gtgttcgcca ccggttacga ggcgatgcag ggcagctaca acaagatcga catccggggc
     7441 gcgggcggcc gctcgctgaa ggagcactgg ggcgaggctc ccagcagcta cctgggcgtg
     7501 gccaccaacg gattcccgaa cctgttcacg gtcttcggcc cgaacagcgt cttctccaac
     7561 ctgccgccgg ccctgcagac gcaggtcgag tggatctccg acaccatcgg cgaggcccgc
     7621 aagcgtggcg tcggccgggt cgaggcgacc gccgcagcgg aggaggaatg gacggtgatg
     7681 tgccgtgaga tggcccagca cagcctgttc gcgcagaccg actcctggat cttcggctcc
     7741 aacattcccg gcaaggagcg ccgcacgctc ttctacttcg gcggaatcgc ggcctaccgc
     7801 gagaagctga aggagatcgt cagcgcggac tacgagggct tcaccctcga cggggaagcc
     7861 gcgccgagcg cggtctgacc ggcgcgggcg cgtaggcagg gaggcaccgt ggacaccgcg
     7921 tccggcgtcg gaagctccgt cgccggacac ggtgccacgg tgccgtcgtg tgcgagggca
     7981 ccgcaccgga caatccgtat ccggcagttg tacgctccgc acggtcttgt tcactcaggc
     8041 gacatccgta atgatggcgg atgcccttcc cggcttcgcc ggagagccgc cgcagttgac
     8101 agtccctgcg tatttcctgt ttcgcggctt ttgtctaagg gatccgaatt cacgccgggc
     8161 gcgagcattt tcatgagtca atggatgtgt ggcccggaaa atgggagcgt tgctagcttc
     8221 ggacgtatga ctgaaaccgt gattcgcgca ggcgacgacg tagcgaccgt gatcaacgtc
     8281 ttcgaaaccc agccggacaa gcagcaggaa cttgtcggtg ttctcaacga gggactcgac
     8341 aaggttgttc ggcaccgtcc gggattcgtc tccgcgacga ttctcgccag caaggacggc
     8401 agcaaggtcg tgaactacgc ccagtggcgc agcccggccg acgcgcaggc cacgttcggc
     8461 gacccggccg ttcaggagta cggcaagaag gccgcggcgc tcggtacccc cgcgcccggt
     8521 gtctactccg tcgactcggt caccctcgcc ccctgaccct cggtccgccc cacttccttt
     8581 tccgcagcgc acgttccggc tccacccgta cgagcgtcac cggacttctt ccacacagct
     8641 catcctgaaa gaaaggcgaa agccgtcatg accgaggcag ctacccccgg catcgtcatc
     8701 gccggggccg ggatcggggg tctggccacc gcgctcgccc tgcacgcccg aggactgagc
     8761 gtcaccctca tcgaggaagc gaaggagatc cggccgctcg gcgtcggcat caacatccag
     8821 cccgcggcga tcggtgagct gaccgctctc ggcctcggcg agaagctggc cgccaccggc
     8881 atcgccaccc gcgaacaccg ctacctcgac cacaagggca acaccctgtg gaccgagccg
     8941 cgcggtatcg ccgcgggcaa cgacttcccg cagtactcga tccaccgcgg cgagttgcag
     9001 atgatgctcc tcgaagcggt gcgcgaacgg ctcggcgacg acgcgatccg tacgaacacc
     9061 cgggtgcgcg gcttcgacca ggacgccgac ggggtgcggg tgcacctgag ttcacccgtc
     9121 gacggcgact cgaccatcga ggcgtccgta ctgctcggcg cggacggcat ccactcgccg
     9181 atccgcgccc agctgcaccc ggagggctcg ccgctgcgca agaccgccgt gcggatgtgg
     9241 cgcggtctgg ccgagctgcc cgagttcatc gacggccgga cgatgatcat cgcctccgac
     9301 gacaacgcca accgccttgt ggcgtacccc tgttcgcggc cgcacgcgga ccagggcaag
     9361 gtcctgttca actgggtgtg cctggctgcg gacccgaagt gggacggcga ggtgcagctc
     9421 accccgggcc gtatcgagga cgtcctggag cacttcagcg actgggactt cggctggctc
     9481 gacgtccccg cgaccctgaa gtccagcccg caggtcatgc accacatcat ggtcgaccgc
     9541 gacccgctgg agacctgggg cgagggccgg gtcaccctgc tcggcgactc ggcgcacccg
     9601 atgtacccga tcggtgccaa cggcggcacc caggccatcc tcgacggcat caccctcgcg
     9661 agggaactcg ccgaggcggg cgacgacatc cctgccgccc tgcaacgcta cgagagcgtc
     9721 cggcgcccgg ccaccaacga gatcgttacg gccaaccgca agatggaccg ctccgagcgc
     9781 gatctggcgg gcaccaaggg cgatgtggcg gacgaactgg agaccatcac caccgactac
     9841 cgggacgtcg tcgagaagtc gcacgcctag acgcgtcctc gagcgggcgc cggttcgccc
     9901 ggccccgctc accccggtca cccccacctc tccgcccggc gggccggaat ccgggccgcc
     9961 gccgccccca gtggcacggt tcccggccgt gccgcagaac gaaaagaaag aaaggcagag
    10021 atgtcagcca ccgcagtctc ggcccgcgag aagttgtcgc ggatcctgac cgacaccagt
    10081 gaggacgatc cgcagcgtcc gccactgggc acccagctca agtactactt ctacatccgc
    10141 cgccccgagt tcctgcccgg ccacatcctg atcggcctcg cgccggccat gctggccgcc
    10201 accagctggg acgagttcac ctccgtgaac gcggtggtgg cgatcctgtt cgcgatcgtc
    10261 aacatgcagc tggccgacca gatcaacgcc ctggccgacc gctgggagga cgcggcgaac
    10321 aagtcgcgcc tggccacggc cgtctacggc ctcggcgtca agcgcgtggt cggtgacgtc
    10381 atcgtcacca gcctcgtcta catcgccatg gcggtgttcc tggccgcgaa gaccgggcac
    10441 tgggacctgt tgctgatcgt ggcggcgggc tgggtcgtgg gcatgcagta ctcgctcccg
    10501 ccgtggcacc tcaagagtgc cggtgtcggc cagctcttcg gcctgtacct gtgggtctgg
    10561 atcccgatgc tgttcgtgct gcgcgcgttc gacaacgagc tgcagtggac caacgtcgtg
    10621 gccaccgccg cgctgacggt gatactggtc gccctcttca ccacgaacca gatcgaggac
    10681 ttcttcgacg acgaggaatt cgacgtacgg acatacgtcc gtgcccttgg catcaagaag
    10741 acgctcgccg tccagtccac gatcctgtgc gtcgcgtccc tggtgatcgt cgctgccgtg
    10801 tggcagaact ccggcttcaa ctggggcatg atcccgttcc tcgccgcgtg gctggtctgc
    10861 cagggataca tgtactccct gtccaaggcc gctggagcgc cgatcgagaa tgtggtcgac
    10921 agcgtcaaga agaagtcgct tgtcggcccg tacttgagca tgctgatgag cagcatgacc
    10981 actgtggtgg gcatcggggt tctcgcctga ccgcatccga ccgagtcggc cggaccggcg
    11041 ctggcatcgt ccagcccggc ccggccgccg cggccgtgcg gatgtgcggc gccgggaaac
    11101 aaggctcttg aatatcggta tggaccacgc agcagacgca tcggacgcgg tgaaccgttc
    11161 accgcggcaa gaggcacgac catcactcgg cgaacggcgc agcgcaccac ccagcaagcc
    11221 acgcagcacg ccactcagca agccaggtag acaacaaggg gggttgagcg cgttgacttc
    11281 gccgacgtcg gcacaggggc tgccgaggca cttcggtact cgccgtatcg gaatcgggcg
    11341 cgcacacggc aagatcatcc tgatcgggga gcacgcggcc gtctacggcg cgcccgcact
    11401 cgccggtccg gtgcctcagt tgccggtgac agccagcgtc gcacagcttc ccgatgccga
    11461 aggtggtagc ggggaagcgt ccttctcggt caccagtgcg gtgaccggaa ccgtcgcgat
    11521 gaaggcaaca gacggactcc agcgccttgt cgtggagttc aaggaacgta ccgaggtcac
    11581 cgaccagcag cacatcgacg tggtcgtgga ctgcgagatc ccgctcggcc ggggcctcgg
    11641 ctccagcgcc gcctgcgccc gcgcgatcgt gctcggactc gcggacctct acgaccgtga
    11701 actcgacgag gacaccgtct tcgagctggt gcagatcgcc gagaacgtgg cccacggccg
    11761 ggccagcggc gtggacgccc tcgccaccgg cgcccgggca cccttcctgt tctcggccgg
    11821 aaccgccgac acattgccca ccgcccgtga aacgcccatc ggcctcgacg gtttcctcgt
    11881 catcgccgac agcggcgagg cgggcgggac ccgtgaggcg gtggagatgc tgcgcgcctc
    11941 cttcggccgc gaggagggct cccaggagcg gtttttgact cgcgcgaacg aactgaccgg
    12001 cgcggccgta cgcgacctcg ccgagggccg ggtggccgag ctcggcgaaa gcttcaccgc
    12061 ctaccacgag ctgttgcgcg cggcggcatt gagcacgcag cgcatcgacg ccctggtcga
    12121 ggccgcactg gcggccggaa gccacggcgc caagatcagc ggcggcggac tcggcggctg
    12181 catgatcgcg ctggccgacg ggacggacca ggcgcgccac atcgagaccc ggctgcgcga
    12241 ggccggtgcg gcgcggacct ggaccacgcc cctgaaaagg agcaccgacc gtgccagcta
    12301 gcagctcaga aagcccgggc ggcccagcga gggccaagag ccccgcgagc tcccaccact
    12361 cgccgaacac cgaggaagca cgcaccatgc aggagccggt caccgagggc ggcgcgaccg
    12421 ccgtcgccca gccgaacatc gccctgatca agtactgggg caagcgcgac gagcagctgt
    12481 tcatcccgat gaccagcagc ctgtcgatga ccctggacat cttccggacc accacgacgg
    12541 tccgcctcgg caccgaggcc gacgtcgaca gcgtggccct gaacggcaag gccgcctcgg
    12601 gcgaggcgga gcgccgggtg ctcgtcttcc tcgacctggt acgggagttg gccgggcgca
    12661 aggaacgcgc cgtggtcgac acccacaacg aggcgccgac cggtgcgggc gtcgcctcct
    12721 ccgcgagcgg cttcgccgcc ctggcgctcg ccgcctcggc cgcgtacggc ctcgacctgg
    12781 acgcgcgggc gctgtcccgg ctcgcccggc gcggctccgg atcggcctcg cggtcggtct
    12841 acggcggctt cgtgcagtgg cacaagggcc agggcgaggg cgccgacgcc gacctctcct
    12901 cgtacgcgga gccggtgccg gtcggcgaca tcgacccggc ccttgtgatc gcgctcgtcg
    12961 acggcggccc caagtccgtg tccagccgcg ccgcgatgcg cagcaccgtc gacacctcgc
    13021 cgctgtacca gggatgggcg gactccagcg agggcgacct gaccgagatg cgacgggccc
    13081 tgagccgcgg tgacttcgag gcggtcggcg agatcgcgga gcgcaacgcc ctcggcatgc
    13141 acgccaccat gctggccgcg cgtcccgccg tgcgctacct gtccccggcc accgtcacgg
    13201 tgctcgaccg ggtgctccag ctccgcgccg acggcattcc cgcgtacgcc accatggacg
    13261 ccggacccaa cgtcaaggtg ctctgccgcc gcgcggacgc ggaccgggtg gccgaggccg
    13321 tacgcgaggc gatgacggcc ggctcggtcg tggtggccgg cagcggcccc ggcgcgcggc
    13381 tgctcaccga gggcggctga tgcccgccca gcaagcggtg acacggcgcg caccgggcaa
    13441 gctcttcctg ctcggcgagt acgccgtcct ggagcccggc accccgtcga tcctgatggc
    13501 ggtcgaccgg tacctcggcg tcacggtgtc ggtgccggag gaggccgacg ggccggacgg
    13561 accgggggac ggcgcggaca tcgtcgtcgt cacggagctg ctgcccgaac cggcccggtt
    13621 cacacggcag ttggacggcg aaccgctctg gtgcggcccc gccgagcagg agcagagcgc
    13681 ccgcgcggcg ctggcacaca ttctctccgt cgtcggcgta ctggacgcgc tgctggccga
    13741 gcacggccgg aaggcacccg ccttccgcct ctcggtgagc agcgaactcc acgagggcgg
    13801 aacgaagttc gggctgggtt cgagcggtgc ggtgacggtg gccagtgtcg ccgccctcgc
    13861 cgcgtactac ggactcgacc tcacgcggga cgagcgcttc cggctcgccc tgctggccac
    13921 cgggcgcctc aacgccagtt cctcctgcgg ggatctggcg gcgagcacct tcgggggctg
    13981 gatcacctac cgggcgccgg accgggccga ggttgtcgca atggcgcgac agcacggcat
    14041 cggagagtcg ctgcgcgccc attggccggg atacgaggta cggcccctgc cgtcaccgcc
    14101 cggcctcagt accgagatcg gctggaccgg cacacccgcc tccaccgacg cgctggtctc
    14161 gggcctcggc aggcgcaaat ggcggggcac cgccgcccat cgggccttcg tggccgcgac
    14221 ggacgagtgc gtgcgggcgt cggtgaaggc catcgaacag ggggaccgcg acgagttgct
    14281 ggaccggatc cggagcgcac ggacgacact cgcccagctc gacgaagagg tggggctcgg
    14341 tgtcttcacc agcaggctga ccgcgctgtg cgaggtcgcc gaggagctgg gtggtgcggc
    14401 gaaaccctcc ggggcggggg gcggcgactg cgggatcgcg ctgctgcccg tcgaacggga
    14461 gccggaaatc cgacagttgc ggacacggtg ggccgccgca ggggtgcgtc atctgcccct
    14521 gcgtcccgcc gaggtaagta caaccgaaag gaatgcgcgc aatgatcgct gaacgcaagg
    14581 acgatcacgt ccggctcacc gtcgagcaac agcgtcggct cagcgggcag aacgagttcg
    14641 acgacgtcag gttcgtccat cacgctctgg ccggtatcga ccgcgacgat gtgtcactgg
    14701 ccaccagctt cgccggtatc gactggcaag cgccgatcta catcaacgcg atgaccggcg
    14761 gcagcgtcaa caccggcgtc atcaaccggg acctggccat cgccgcgcgc gagaccggcg
    14821 tcgcgatcgc caccggttcc gtgagcgcct tcttcaagga cccgtcctcg gcggagacgt
    14881 tcagtgtgat gcgccgggag tacccgggcg gcttcatcat gggcaacgtc aacctcaacg
    14941 ccaccgccga ccaggcgcgc aaggccgttg agctgcttga ggccaacgcc ctccagatcc
    15001 acctgaacac gatccaggag accgcgatgc ccgagggcga tcgcgagttc tcgcactggc
    15061 agtcgcggat cgaggagatc gtcaccgccc tcgacgttcc ggtgatcgtc aaggaggtcg
    15121 gcttcggcct cagccgcgag accatcgcca ccctgcagaa gctcggcgtg cacgtcgccg
    15181 acgtcggcgg gcgcggcggc accaacttcg cccaggtgga gaacgaccgc cgggacgtcg
    15241 ccgacttcgg ctacctcaac gactggggcc tgtccaccgc ggcctgtctc ctcgacgccc
    15301 aggacgcggg cataccggta ctggcctccg gcggcgtacg caacccgctg gacgtggccc
    15361 gcagcctcgc gctcggcgcc tcggcggtcg gtgcctccgg cggtttcctg cgctcgctga
    15421 tggacggcgg ggtcgacgcg ctggtcaagc acatcaacac ctggctggac cacctgtcgg
    15481 cgatcatgac cgcactgggc gcccgcactc cggccgaact ggcccactgt gatgtcctta
    15541 tcaagggcga gctgcgggac ttctgcgccg atcggggcat cgagaccggg ccgctgagca
    15601 ggcgttcgac gcgcctggcc gccaccgagc agacgacggg aagcgcacga tgagcgacat
    15661 caccaccgcc ggggtcccca tgaagtgggt gggaccgatg cggatctcgg gcaacgtagc
    15721 caccaccgag gccgaagtcc ccctggcgac ctacgaaacc ccgctgtggc cgtccgtcgg
    15781 ccggggcgcg aagatctcca tgctgaccga gaagggcatc gtcgccaccc tggtggacga
    15841 gcggatgacc cgttccgtgc tcgtcgaggc cgaggacgcg cagaccgcgt acgcggccgc
    15901 gcagcagttg gaactgcgct tcgaggacct gcagaaggtc gtccgtacct gcagccggtt
    15961 cgccgaactg gtcaaggtgc ggcacgagat cgcggccaac ctgatgttca tccggttcga
    16021 gttcaccacc ggtgacgcct ccggacacaa catggccacc ctcgccgcgg acgccctgct
    16081 gacccacatc ctgcagacga tcccgggcct gtcctacagc tcgatctcgg gcaactactg
    16141 cacggacaag aaggccaccg cgatcaacgg catcctcggc cgcggcaaga acgtcgtgac
    16201 cgaactgctc gtcccgcgcg agatcgtgga gagccggctg cacaccacgg ccgacaaggt
    16261 cgccaagctg aacgtgcgca agaacctgat cggcaccctc ctcgcgggcg gcatccgttc
    16321 ggccaacgcc cacttcgcga acatgctgct cggcttctac ctggccaccg gccaggacgc
    16381 ggccaacatc gtcgagggct cgcagggcgt caccttcgcc gaggaccgcg acggcgacct
    16441 gtacttctcc tgcaccctgc cgaacctgat cgtgggcacc gtcggcaacg gcaagggcat
    16501 cgacttcgtc gaggagaacc tgatccggct cggctgccgc gaggagcgcg agccgggcga
    16561 gaacgcgcgg cgcctggccg tgctgtgtgc cgcgaccgtg ctctgcggtg agctctcgct
    16621 gctcgccgcg cagaccaacc cgggcgaact catgcgcgcc cacgtccaat tcgaacgcaa
    16681 gaattcttcg acacaggccg gggtgtagcg gatgagcgca aacggaaacc acacgcaggg
    16741 cggcaacaac ggcagcaacg cgacgggcgg aaccggcggc gcgatagccg tcggcatcga
    16801 ggacctctcc ttcgccacca cggagtacgt cctgccgcac accgaactcg ccgcgtacaa
    16861 cggcaccgag atcggcaagt accacctggg catcggccag cagtcgatga gcgtcccggc
    16921 ggccgacgag gacatcgtca cgatggccgc ggccgccgcg gcgccgatcg tggcccggca
    16981 cggcgcgggc cgcatccgca ccgtcatcct ggccaccgag tcctccatcg accaggccaa
    17041 ggcggccggt gtctacgcgc actcgctgct cggactgccc gccgcgaccc gcgtggtcga
    17101 gctcaagcag gcctgctacg gagccaccgc cgccctccag ttcgccatgg gcctggtcta
    17161 ccggaacccc tccgagcagg tcctggtcat cgccagcgac gtctccaagt acgacctcga
    17221 cagccccggc gaggccaccc agggcgccgc cgccgcggcc atcctggtgg gcgccaaccc
    17281 ctccctcctg cgcatcgaac cggcctccgg cctgttcacc gccgacgtga tggacttctg
    17341 gcgccccaac taccgcgaca ccgcgcttgt cgacggccag gagtccatct ccgcctacct
    17401 ccaggccgtc gagggctcct ggaaggacta cagcgagcag ggcggccgtt ccctggagga
    17461 cttcgccgcc ttctgctacc accagccctt cacgaagatg gcgtacaagg cccaccgcca
    17521 cctcctccac tactgcggcc acccggtcga gaacgacgag gtcgcccgcg tcctggaacc
    17581 gaccaccacg tacaactccg tggtcggcaa cagctacacg gcctccctct acctcggcct
    17641 cgccgccctc ctcgacagcg acgccgacct gaccgaccgc gccatcggcc tcctcagcta
    17701 cggctccggc agcgtcgccg agttcttcgc cgccaccgtc gtccccggct accgcgccca
    17761 cctgcgcacc aaggcccacc gcgaggcgat cgaccgccgc aagcccatcg accacgccac
    17821 ctaccgggaa ctgcaccagc gctccttccc gacggacggc ggggactacc cggtaccggc
    17881 gcagacgagc ggcccgtacc ggttctcggc gctctcgggc cacaagagga tctacgagcc
    17941 gcgctga
//
