BGC0002564: megapolibactin Acyc biosynthetic gene cluster from Paraburkholderia megapolitana
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Location: 882,299 - 955,558 nt. (total: 73,260 nt).
This entry is originally from NCBI GenBank CP041745.1.

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NRPS/PKS domains
General information about the BGC

MIBiG accession | BGC0002564
Short description | megapolibactin Acyc biosynthetic gene cluster from Paraburkholderia megapolitana
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- NRPS (Type I)

Loci
CP041745.1
901250 - 941056
via
Compounds

- megapolibactin Acyc
- megapolibactin Bcyc
- megapolibactin A
- megapolibactin B
- megapolibactin C
- megapolibactin D
- megapolibactin E
- megapolibactin F

Species Paraburkholderia megapolitana [taxonomy]
References

- [1] Genomics‐Driven Discovery of NO‐Donating Diazeniumdiolate Siderophores in Diverse Plant‐Associated Bacteria. Hermenau, R et al., Angewandte Chemie International Edition (2019) DOI:10.1002/anie.201906326
- [2] Genomics-Driven Discovery of NO-Donating Diazeniumdiolate Siderophores in Diverse Plant-Associated Bacteria. Hermenau R et al., Angew Chem Int Ed Engl (2019) PMID:31276269

Chemical products information
megapolibactin Acyc Evidence:
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Chemical database entries
NPAtlas
megapolibactin Bcyc Evidence:
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Chemical database entries
NPAtlas
megapolibactin A Evidence:
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Chemical database entries
NPAtlas
megapolibactin B Evidence:
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Chemical database entries
NPAtlas
megapolibactin C Evidence:
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Chemical database entries
NPAtlas
megapolibactin D Evidence:
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Chemical database entries
NPAtlas
megapolibactin E Evidence:
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Chemical database entries
NPAtlas
megapolibactin F Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
FNZ07_17525 QDQ83025.1 | 901250 - 901495 (+) | MbtH family NRPS accessory protein |  |  | copy AA seq copy Nt seq
FNZ07_17530 QDQ83026.1 | 901499 - 902311 (+) | thioesterase |  |  | copy AA seq copy Nt seq
FNZ07_17535 QDQ83027.1 | 902299 - 903267 (+) | TauD/TfdA family dioxygenase |  |  | copy AA seq copy Nt seq
FNZ07_17540 QDQ83028.1 | 903368 - 904804 (+) | peptide synthetase |  |  | copy AA seq copy Nt seq
FNZ07_17545 | 904963 - 905736 (+) | YqcI/YcgG family protein |  |  | copy AA seq copy Nt seq
FNZ07_17550 QDQ83029.1 | 906252 - 907949 (+) | cyclic peptide export ABC transporter |  |  | copy AA seq copy Nt seq
FNZ07_17555 QDQ83030.1 | 907974 - 908813 (+) | ATP-binding cassette domain-containing protein |  |  | copy AA seq copy Nt seq
FNZ07_17560 QDQ83031.1 | 909150 - 913751 (+) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
FNZ07_17565 QDQ83032.1 | 913834 - 929922 (+) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
FNZ07_17570 QDQ83033.1 | 930009 - 935558 (+) | amino acid adenylation domain-containing protein |  |  | copy AA seq copy Nt seq
FNZ07_17575 QDQ85939.1 | 935877 - 938030 (+) | TonB-dependent siderophore receptor |  |  | copy AA seq copy Nt seq
FNZ07_17580 QDQ83034.1 | 938079 - 939053 (+) | ABC transporter substrate-binding protein |  |  | copy AA seq copy Nt seq
FNZ07_17585 QDQ83035.1 fhuB | 939050 - 941056 (+) | Fe(3+)-hydroxamate ABC transporter permease FhuB |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 2

Date
Changes
Submitters
Reviewers
2022-10-07
Added chemical structures for compounds: megapolibactin Bcyc, megapolibactin Acyc.

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-10-07
Added NPAtlas links to compounds: megapolibactin Bcyc, megapolibactin Acyc.

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Entry added

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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