LOCUS       BGC0002573              7021 bp    DNA     linear   BCT 25-MAY-2019
DEFINITION  Streptomyces mozunensis strain MK-23 phosphoramidon gene cluster,
            complete sequence; and TalB (talB) gene, complete cds.
ACCESSION   BGC0002573
VERSION     BGC0002573
KEYWORDS    .
SOURCE      Streptomyces mozunensis
  ORGANISM  Streptomyces mozunensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 18:01:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7021
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..2139
                     /gene="talE"
     CDS             1..2139
                     /codon_start=1
                     /gene="talE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /note="PEP synthase/PPDK phosphodiesterase"
                     /product="TalE"
                     /protein_id="QCR99099.1"
                     /sec_met_domain="PPDK_N (E-value: 8.8e-37, bitscore: 115.4,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSDRNKATTRPRLTGEKLTTQEFSRLAGTIGGYPYVKIVLDRT
                     ESVLHFIDSADGTLHVRYIGCEILGMSLDELARGLDSFNDDVYRNPDRRFYLGTLALHS
                     RRGDGRGDGGGTGEGRAAGAFLSLETVDVDTMSQEMLRFFYHRVRDHIDPTLPLVLKPA
                     NHRQEDYVAGIPESEIPRVLSHELYSTASFVPLNDGQAHGRLRVFRSEAEYRADPEPLE
                     WHDIVVMPRVPEDIPRVSGIIHTEHTTPLSHINVMAAGWRIPNAVGTEAVDRIERAGLA
                     GRWVHYRVDADGSDLHLEAAQPHSDGVPPTPPAERVLVDRPDLAPTPITALSELRAGDH
                     VRFGTKAANLGELTHLLQHGSPRWLGFYRAPRPPRDNLLRYLARQLGLPENADEAELVA
                     AAQRLVKEYTQVPRGIVLPFSLQQRFLDSSAELRSVLGRLDSALLSGTSQTSQTLQTPQ
                     ATQLGELCREAQRLIRTTPLPDPVRTEIDRALDRHLYGAPVLVVRSSSNAEDLPGFSAA
                     GLYESVANVGGTSPVHGAAHEAVDGEVHEAALDGVLDAVREVWASLLSPRAVLLRHQAG
                     IPLDHCGMGVIVQEQVGATVGGVLVTCNPLSPQDFRNVYLNISPRSVTEVVSGQGAPLQ
                     YLCNTMEGGSRTVSLGTATADLDAATKDLVGRLALISRLLQSHFSPDESYADPVDIEWA
                     IEDDRVSLLQLRPFRTAG"
     source          1..7021
                     /db_xref="taxon:2577050"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces mozunensis"
                     /strain="MK-23"
                     /type_material="type strain of 'Streptomyces mozunensis'
                     Fukuhara et al. 1982"
     misc_feature    1..7021
                     /note="phosphoramidon gene cluster"
     subregion       1..7021
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7021
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            2222..3577
                     /gene="talD"
     CDS             2222..3577
                     /codon_start=1
                     /gene="talD"
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     bacilysin"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 67.7; E-value: 1.7e-20)"
                     /gene_kind="biosynthetic"
                     /note="ATP-grasp enzyme"
                     /product="TalD"
                     /protein_id="QCR99100.1"
                     /sec_met_domain="bacilysin (E-value: 4e-59, bitscore:
                     188.8, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILYVYVKGGAPLEYAFPRIAACGELHVLALAPLPTTAADAWR
                     PSCTSIELVPEAPRGEELVELIVEYAKAIGADAVLTLSEFAVLAVAHAAHRLGLAGAGE
                     GIVRARDKRLMREAWAAAGVPIPGFRRVDSLADLDAALAEFTPPLLLKPAWGAGSVAQI
                     VLDSAADAAPAWSEIERGLQAGSRVGMNELYAADTDRDRLVEEIAQGSTEGWYQEPGYG
                     DYVSVEGIVADGVYRPLAITAKLPTVPSFVEVASTSPSVMPVPLQRRIEEVSRQAVDAL
                     GLENCGTHTELKLMKDGELVVIETAARFGGLLTTRQVHEVFGFDPIGMLVRQLLGERVD
                     YPEVMLTDGVRAAASVAVVPADAFGVPWRTRPVWNPQAVDWQSLLSPGSTIEAVPAFAM
                     PAGQPVPAFDPAAGSRNWLGVYLLSAVDAATLQRDCNAVLNGLEAALHRAAS"
     gene            3610..4749
                     /gene="talC"
     CDS             3610..4749
                     /codon_start=1
                     /gene="talC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 268;
                     E-value: 2.8e-81)"
                     /gene_kind="biosynthetic-additional"
                     /note="glycosyltransferase"
                     /product="TalC"
                     /protein_id="QCR99101.1"
                     /sec_met_domain="MGT (E-value: 1.2e-111, bitscore: 362.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFAGAPGFGHLFPLVPLARAMRELGHEVAVASMDGGEPVAGS
                     GLPYLSIAPGVDWRKEIREAGRTRRPDLMRRVVESNSADREAFVPLAAHVNSRVADEMV
                     ELATRWRPDLVVYEYQFPVALLAAARLGVPAVQHDLGFVRTPKLRALMLAEMADTFARH
                     GIDRLPEPADIIDLAPPSTAGEERYGSSMRPVAYNGEGEVPDDLAVPAHRPRVAVTLGT
                     VPPKTDGLTRIERVIAAAADVDAEFVLATGELDLSTLGTLPDNVRPYGWVPWRALLETC
                     AAAIHHGGSSSALGALDAGIPQLVLPDGSDRFITADAVRDRGAGLSAGAEEIGPALLDR
                     LLTDDALARAAREVSAEIATMPSPRELAQRLTAPGAITG"
     gene            complement(5187..6404)
                     /gene="talB"
     CDS             complement(5187..6404)
                     /codon_start=1
                     /gene="talB"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 57.7; E-value: 1.3e-17)"
                     /gene_kind="transport"
                     /note="MFS transporter"
                     /product="TalB"
                     /protein_id="QCR99102.1"
                     /transl_table=11
                     /translation="MPLTTASAPPETSPGRAAPAGGALLVLGFVLLSLNTRVAFGQVGP
                     LAPVAGWGQGTVTVLGLLPPLCMGLFAPLGALARRRIGEERGLFWASVLLVAGAALRPT
                     GLAGLYAGTVLVGIAVAVVNVLIPVFVRARFAPQRIGTMMGVYALSMGAGSAVVAALVA
                     PVADAWSWRAAVALAVVPAVLAAAGMAPQLRVDRPIPAAAAPVHRRPVGRTALAWSLTA
                     FFGIQTLVFYATLAWLPTILVDAGLSRTAAGTDQAVLILGLAVGGFLAPVLAAARADQR
                     PHILAVVAVCVLGLLGVLLAPAAGAPVWAGVLGIGMGGGQALAGVLFARRGTDHDHVAA
                     LSTMAQTCGYLLAATGPALAAALHGATGTWTTPLLALVALLLAGSVLSLRAGHSVTKPH
                     RDPSNR"
     gene            6515..7021
                     /gene="talA"
     CDS             6515..7021
                     /codon_start=1
                     /gene="talA"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     65.9; E-value: 1e-19)"
                     /gene_kind="regulatory"
                     /note="MerR family TR"
                     /product="TalA"
                     /protein_id="QCR99103.1"
                     /transl_table=11
                     /translation="MARLYSITEVAEAFGLSVPALRYYEDCGLITPAARRGRVRHYDRA
                     ALERLALVQLWHVDGMIPLAGTAAVMASEQAAERKALLAAQRDEMTARARRLERAAAVL
                     THMLDCHRDRPLECPVTRAHIDARVDAALAGEELADDFLPPNEPAQSLSGPSAAPPASA
                     RRGGR"
ORIGIN
        1 atgacccgtt cggatcgcaa caaagcgacc acgcggcccc gcctgaccgg cgaaaagctc
       61 accacccagg agttttcccg gctggccggc accatcgggg gctatcccta tgtgaagatc
      121 gtgctcgacc ggaccgagtc cgtgctccac ttcatcgaca gcgccgacgg caccctgcac
      181 gtccgctaca tcgggtgcga gatactcggc atgtcgctcg acgaactggc ccgcgggctc
      241 gattcgttca atgacgacgt ctaccggaat cccgatcgcc gtttctatct cggtaccctc
      301 gccctgcact cccggcgcgg tgacgggcgc ggtgacggag gcggtaccgg agaaggccga
      361 gcggccggcg ccttcctgtc cttggagacc gtcgacgtcg acaccatgtc ccaggagatg
      421 ctgcgcttct tctaccaccg ggtgcgcgac cacatcgacc cgacgctgcc gctggtcctc
      481 aagccggcca accaccggca ggaggactac gtcgccggga tcccggagag cgagataccg
      541 cgcgtcctgt cgcacgagct ctactccacg gcctccttcg tgcccctgaa cgacgggcag
      601 gcccacgggc ggctgcgggt gttccgctcc gaggcggagt accgggccga ccccgagccg
      661 ctggagtggc acgacatcgt ggtgatgccc cgggtgcccg aggacatccc ccgggtgtcg
      721 ggcatcatcc acaccgaaca caccacgccg ctctcccaca tcaacgtgat ggccgccggg
      781 tggcggatcc ccaacgccgt cggcaccgag gccgtcgacc ggatcgagcg ggccgggctg
      841 gccgggcgat gggtccacta ccgggtcgac gccgacggct ccgacctcca cctcgaagcc
      901 gcgcagccgc attccgacgg cgtcccgccg acgcccccgg ccgaacgcgt cctcgtggac
      961 cggcccgacc tcgcgcccac cccgatcacc gccctgtccg agctgcgcgc gggcgaccac
     1021 gtccggttcg gcaccaaggc cgccaacctc ggtgaactca cccacctgct gcagcacggc
     1081 tcaccccgct ggctcggctt ctaccgcgcc cccaggccgc cccgggacaa cctgctgcgc
     1141 tacctggccc ggcaactcgg cctcccggag aacgcggacg aggccgaact ggtcgccgcc
     1201 gcccagcgcc tggtgaagga gtacacccag gtgccgcgcg ggatcgtgct gccgttctcg
     1261 ctccagcagc gtttcctcga ctcctcggcg gagctccgga gcgtcctcgg ccggctcgac
     1321 tccgcgctcc tgagcgggac ttcgcagacc tcgcagaccc tgcagacccc gcaggccacg
     1381 cagctgggag agctctgccg cgaagcgcag cggctgatcc gcaccacccc gctgcccgac
     1441 ccggtccgca ccgagatcga ccgcgcgctc gaccggcacc tgtacggcgc acccgtcctg
     1501 gtcgtgcgca gctcgtccaa tgccgaagac ctgcccggct tctccgccgc cggactctac
     1561 gagtcggtgg cgaacgtcgg cggcacgagc ccggtccacg gcgcggccca cgaagcggtc
     1621 gacggcgagg tccacgaagc ggccctcgac ggggtcctcg atgcggtccg ggaggtctgg
     1681 gcctcgctgc tctcaccgcg cgccgtactg ctgcggcacc aggcgggcat ccccctggac
     1741 cactgcggca tgggcgtgat cgtccaggag caggtcggcg ccaccgtcgg cggcgtcctg
     1801 gtcacctgca acccgctgag cccgcaggac ttccgcaacg tctacctcaa catctcgccg
     1861 cgctcggtga ccgaggtggt ctccggtcag ggcgccccgc tccagtacct gtgcaacacc
     1921 atggagggcg gcagccgcac ggtctcgctg ggcaccgcca ccgccgacct ggacgccgcg
     1981 accaaggacc tcgtgggccg actggccctg atcagccggc tgttgcagtc gcacttctcg
     2041 cccgacgaga gctacgccga cccggtcgac atcgagtggg cgatcgagga cgaccgggtc
     2101 agcctgctgc agctgcgccc cttccgcacc gccgggtgac accggctgag tggcaccagc
     2161 cgggtgcgac atcgcccgaa cgcgacacgg gccgagtgaa cttccttcag gagaaagcac
     2221 gttgaacagg attctgtacg tctacgtcaa gggcggcgcc ccgctggagt acgccttccc
     2281 gcggatcgcc gcctgcgggg agctgcacgt cctcgcgctg gcgccactgc ccacgaccgc
     2341 ggcggacgca tggcggccca gttgcaccag catcgagctg gtgcccgagg cgccgcgcgg
     2401 cgaggaactg gtcgagctga tcgtggagta cgcgaaggcc atcggggccg acgcggtact
     2461 gacgctctcg gaattcgcgg tgctggccgt cgcccacgcc gcgcaccggc tcggcctggc
     2521 cggggccggc gaggggatcg tccgggccag ggacaagcgg ctgatgcggg aggcgtgggc
     2581 cgccgccggc gtgccgatcc ccgggttccg ccgggtcgac agcctcgcgg acctggacgc
     2641 cgcgctggcc gagttcacgc ccccgctgct gctcaagccg gcctggggcg ccgggtcggt
     2701 cgcccagatc gtgctcgact cggccgcgga cgccgccccc gcgtggagcg agatcgagcg
     2761 cggcctccag gccggcagcc gggtcggcat gaacgagctc tacgccgcgg acaccgaccg
     2821 ggaccggctg gtcgaggaga tcgcccaggg ctccaccgag ggctggtacc aggagcccgg
     2881 ctacggcgac tacgtgagcg tggagggcat cgtcgcggac ggtgtctacc gtccgctggc
     2941 catcaccgcc aagctgccga ccgtgccgtc cttcgtcgag gtggccagca cctcgccctc
     3001 cgtcatgccg gtgccgctgc agcgccggat cgaggaggtc tcgcggcagg ccgtcgacgc
     3061 gctcgggctg gagaactgcg gcacccacac cgagctcaag ctgatgaagg acggcgagct
     3121 ggtggtcatc gagaccgccg cccggttcgg cggcctgctg acgacccggc aggtccacga
     3181 ggtgttcggg ttcgacccga tcggcatgct ggtccggcaa ctgctgggcg agcgggtcga
     3241 ctaccccgag gtcatgctca ccgacggggt ccgggccgcc gcgtcggtcg ccgtcgtccc
     3301 cgccgacgcg ttcggcgtgc cctggcgcac caggccggtc tggaacccgc aggccgtgga
     3361 ctggcagagc ctgctgtcac cgggcagcac catcgaggcc gtacccgcct tcgccatgcc
     3421 cgcgggacag ccggtgcccg ccttcgaccc tgccgccgga tcgcgcaact ggctcggggt
     3481 ctacctgctg agcgccgtcg acgccgccac cctgcagcgc gactgcaacg ccgtgttgaa
     3541 cggcctggag gccgccctgc accgggccgc ctcctgatcc cccccatccc gagtaaacga
     3601 ggttccttca tgcgtgtact gttcgccggc gcacccggct tcggccacct cttcccgctg
     3661 gtcccgctgg ccagggcgat gcgcgagctc ggccacgagg tcgcggtggc ctcgatggac
     3721 ggcggcgagc cggtcgccgg gtccgggctg ccgtacctgt ccatcgcgcc gggcgtggac
     3781 tggcgcaagg agatcaggga ggccggccgc acccggcggc ccgacctgat gcggcgggtg
     3841 gtcgagagca attcggccga tcgcgaggcg ttcgtcccgc tggccgccca cgtcaacagc
     3901 cgggtggccg acgagatggt cgagctcgcc acgcggtggc ggccggacct ggtggtgtac
     3961 gagtaccagt tcccggtggc cctgctcgcg gcggcccgcc tgggcgtgcc cgcggtccag
     4021 cacgacctgg gattcgtccg caccccgaag ctgcgcgcgc tgatgctcgc ggagatggcg
     4081 gacaccttcg cccggcacgg aatcgaccgc ctgcccgagc cggcggacat catcgacctc
     4141 gcgccaccga gcacggccgg ggaggagcgg tacggcagct cgatgcggcc cgtcgcctac
     4201 aacggcgaag gcgaggtccc cgatgacctg gccgtgcccg cccaccgccc gcgcgtggcg
     4261 gtgacgctgg gcaccgttcc gcccaagacc gacggcctga ccaggatcga gcgggtgatc
     4321 gcggcggccg ccgacgtcga cgcggagttc gtgctggcga ccggcgagct cgacctcagc
     4381 acgctcggca ccttgccgga caacgtccgc ccgtacggct gggtcccgtg gcgggcgctg
     4441 ctggagacct gcgcggccgc gatccaccac ggcggcagca gcagcgcgct cggcgcgctg
     4501 gacgcgggca tcccgcagct cgtgctgccc gatgggtccg accgcttcat caccgcggac
     4561 gcggtacggg accggggagc cgggctcagc gcgggcgccg aggagatcgg gcctgcgttg
     4621 ctcgaccggt tgctcaccga cgacgcgctg gcccgggccg cgcgagaggt cagcgccgag
     4681 atcgcgacga tgccgagccc gcgcgagctg gcgcaacggc tgaccgcccc cggcgccatc
     4741 accggctgag gccggcccgc ctcatcggtt ctcgaacacg gtgcggcggc cgggcgggag
     4801 gggccggtcc gtcagcccct gccgcccgcc gtcaccagga ggagccgctt cgcggccggg
     4861 cggcgtgggg cgtcctcctg gtcctccgac tcggcgtgtt cgtggtcgag ttcggcgtac
     4921 ccggcgtacc cggcgtaccc ggcgtgctcc tgttcgtccc gcatgcttcc gtcccccctg
     4981 cgtactccgt gtgacgcggg cccgccccct ccggcattcc ggcccgccgc ccggacggcc
     5041 tggtggtgat ccgtccgggc gcggatcggc ccatgcggag agggatgaca ggtcgacagc
     5101 aggccggccg tcagctcggg tgggacttcg ccggggcgct cgtcgacggg ttcgtcggtg
     5161 cgctcctcct gaggtgaacc gtgcggtcac cggttcgacg gatcgcggtg cggcttcgtg
     5221 acagagtggc ccgcgcgcag gctgaggacg gagccggcca ggagcagggc gaccagggcg
     5281 agcagcgggg tcgtccaggt gccggtggcg ccgtgcaggg cggcggcgag cgcggggccg
     5341 gtggcggcga gcaggtagcc gcaggtctgg gccatcgtgg agagcgcggc gacgtggtcg
     5401 tggtcggtgc cccggcgggc gaagagcact ccggccagcg cttggccgcc gcccatgccg
     5461 atgccgagga caccggccca gaccggcgcg ccggcggcgg gggcgagcag gacgccgagc
     5521 aggccgagga cgcagacggc caccaccgcg aggatgtgcg gccgctggtc ggcgcgggcg
     5581 gcggcgagca cgggggcgag gaagccgccg acggcgagcc cgaggatgag cacggcctgg
     5641 tcggtgccgg cggccgtgcg gctcaggccc gcgtcgacca ggatggtggg cagccaggcg
     5701 agggtggcgt agaagaccag ggtctggatg ccgaagaagg cggtgaggct ccacgcgagc
     5761 gccgtccggc cgacggggcg gcggtgcacc ggcgcggcgg cggccggtat cggccggtcg
     5821 acccgcagtt gcggggccat gcccgccgcg gcgagcaccg ccgggacgac ggcgagcgcg
     5881 accgcggccc gccaggacca cgcgtcggcg accggcgcga ccagcgcggc gaccacggcg
     5941 gacccggccc ccatggagag ggcgtagacg cccatcatgg tgccgatccg ctgcggcgcg
     6001 aagcgggccc ggacgaacac cgggatcagc acgttcacca ccgccaccgc gataccgacc
     6061 agcaccgtcc ccgcgtacag cccggccagg cccgtcggcc gcagcgccgc tccggcgacg
     6121 agcagcacgc tcgcccagaa caggccgcgc tcctcgccga tccggcgccg ggcgagcgcg
     6181 ccgagcggcg cgaacaggcc catgcacagc gggggcagca gcccgagcac ggtgacggtg
     6241 ccctggcccc atccggcgac cggcgcgagt ggcccgacct gcccgaacgc gacccgggtg
     6301 ttgaggctga gcaggacgaa gccgaggacg agcagcgcgc cgccggcggg ggcggcgcgc
     6361 ccgggggagg tctcgggcgg ggcggacgcg gtggtgagcg gcatgagcgg cgaacccttc
     6421 gctgcggcag gaagttaggc ttgcctaagc gtccacgctc aagtgtgctt gagtgcaacc
     6481 ccggggcgac ccatgaccgt ggaggagacg gcggatggca cggctctact cgatcaccga
     6541 ggtggcggag gccttcggcc tctcggtgcc cgccctgcgc tactacgagg actgcggcct
     6601 gatcaccccg gccgcccggc gcggccgggt gcggcactac gaccgggcgg cgctggaacg
     6661 cctcgccctg gtccagctct ggcacgtcga cggaatgatc ccgctcgccg ggacggccgc
     6721 cgtgatggcc agcgagcagg cggcggaacg caaggcgctg ctggcggcgc agcgggacga
     6781 gatgaccgcc cgcgcccgcc gcctggaacg cgccgcggcc gtcctgaccc acatgctgga
     6841 ctgccaccgg gaccgccccc tggagtgccc ggtcacccgt gcgcacatcg acgcccgcgt
     6901 cgacgccgcc ctggccggcg aggagctggc cgacgacttc ctcccgccga acgagccggc
     6961 acagagcctg tccggcccta gcgcagcacc gccggcgtcg gcccgtcggg gcggacggtg
     7021 a
//
