BGC0002592 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002592 (Aspergillus terreus NIH2624)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	24,926	geodin	PKS	100%

BGC0002592 - Region 1 - T1PKS

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Location: 1 - 24,926 nt. (total: 24,926 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,927
Label		BGC0002592

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002592	1.00	Polyketide	geodin	Aspergillus terreus NIH2624
BGC0002608	0.38	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0001284	0.37	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0002154	0.36	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001258	0.36	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906	0.36	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001257	0.36	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.36	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.35	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001304	0.33	Polyketide	aflavarin	Aspergillus flavus NRRL3357

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002592	1.00	Polyketide	geodin	Aspergillus terreus NIH2624
BGC0002608	0.70	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0001284	0.69	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0002154	0.69	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001258	0.69	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906	0.69	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001257	0.69	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0002175	0.69	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0000107	0.68	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001304	0.66	Polyketide	aflavarin	Aspergillus flavus NRRL3357

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 24926:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_08451

PKS_AT (938..1237): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methoxymalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 78.5
Methoxymalonyl-CoA: 58.5
Methylmalonyl-CoA: 57.2
inactive: 49.8
Propionyl-CoA: 42.9
Isobutyryl-CoA: 25.2
CHC-CoA: 24.9
2-Methylbutyryl-CoA: 23.7
Benzoyl-CoA: 21.7
Ethylmalonyl-CoA: 20.1
Acetyl-CoA: 18.4
fatty_acid: 18.2
trans-1,2-CPDA: 17.1
3-Methylbutyryl-CoA: 14.3