BGC0002594 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002594 (Fusarium graminearum PH-1 (Gibberella zeae PH-1))

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	31,667	orcinol/orsellinic acid	PKS	100%

BGC0002594 - Region 1 - T1PKS

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Location: 1 - 31,667 nt. (total: 31,667 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 31,668
Label		BGC0002594

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002594	1.00	Polyketide	orcinol, orsellinic acid	Fusarium graminearum PH-1
BGC0001219	0.27	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0002709	0.26	Polyketide	aurofusarin	Fusarium graminearum PH-1
BGC0000156	0.22	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0002507	0.22	Polyketide	sporandol	Chrysosporium merdarium
BGC0001264	0.21	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0002596	0.21	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0001266	0.21	Polyketide	grayanic acid	Cladonia grayi
BGC0001304	0.21	Polyketide	aflavarin	Aspergillus flavus NRRL3357
BGC0001284	0.21	Polyketide	alternariol	Parastagonospora nodorum SN15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002594	1.00	Polyketide	orcinol, orsellinic acid	Fusarium graminearum PH-1
BGC0001219	0.61	Polyketide	shanorellin	Chaetomium globosum CBS 148.51
BGC0002709	0.60	Polyketide	aurofusarin	Fusarium graminearum PH-1
BGC0000156	0.55	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0002507	0.54	Polyketide	sporandol	Chrysosporium merdarium
BGC0001264	0.54	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0002596	0.54	Polyketide	lecanoric acid, orsellinic acid	Claviceps purpurea 20.1
BGC0001266	0.54	Polyketide	grayanic acid	Cladonia grayi
BGC0001304	0.54	Polyketide	aflavarin	Aspergillus flavus NRRL3357
BGC0001284	0.53	Polyketide	alternariol	Parastagonospora nodorum SN15

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 31667:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FGSG_03964

PKS_AT (920..1230): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 66.7%; Propionyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 84.9
inactive: 75.0
Methoxymalonyl-CoA: 51.5
Methylmalonyl-CoA: 48.7
Benzoyl-CoA: 25.6
Isobutyryl-CoA: 24.3
fatty_acid: 23.4
Propionyl-CoA: 10.6
trans-1,2-CPDA: 10.4
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0