LOCUS       BGC0002596             33285 bp    DNA     linear   PLN 15-APR-2013
DEFINITION  Claviceps purpurea 20.1 WGS project CAGA00000000 data, contig
            scaffold00062, whole genome shotgun sequence.
ACCESSION   BGC0002596
VERSION     BGC0002596
KEYWORDS    .
SOURCE      Claviceps purpurea 20.1
  ORGANISM  Claviceps purpurea 20.1
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Claviceps.
COMMENT     Sequencing was performed by University of Kentucky Advanced Genetic
            Technologies Center
            Guldener U., Oeser B., O'Sullivan D., Tudzynski P. Westfaelische
            Wilhelms-Universitaet Muenster
            Institut fuer Biologie und Biotechnologie der Pflanzen,
            Hindenburgplatz 55, 48143 Muenster, Germany
            birgitt.oeser@uni-muenster.de, tudzyns@uni-muenster.de NIAB,
            Huntingdon Road, Cambridge CB3 0LE, UK
            donal.osullivan@niab.com.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 18:03:55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 98652
            Orig. end    :: 131937
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     exon            1..152
                     /locus_tag="CPUR_07423"
     gene            1..1593
                     /locus_tag="CPUR_07423"
     CDS             join(1..152,373..1016,1136..1348,1475..1593)
                     /codon_start=1
                     /locus_tag="CPUR_07423"
                     /note="CP_07423.1"
                     /product="related to monophenol monooxygenase (tyrosinase)"
                     /protein_id="CCE33498.1"
                     /transl_table=11
                     /translation="MALSAIASANPDERLMAKLVKEYQANTIKGLELSRNGSSCTPDNI
                     VVRKEWGNLSLQSRQEYIHAVKCLHELPSKIDPKLAPGARSRYDDFEATHIRLATKIHG
                     TGLFLPWHRHFVYLYEMALRDECGYTGYQPYWDWSKYAYQPIHANPLYDGSKTSMGSNG
                     RYIPGRNGTLQTLPVPGPNPPALYCPPGTGGGYVERGPFASWTLHLGPVIPINVRNGWP
                     VRPNPRPDGLGYNPRRMIRDFNNTLLQENNSYKIVNDLLTNMTDIHTFHPYLTQKPHLG
                     GHFFISDYDNDFYTSPGDPLFYFHHAQVDRIWSIWQALDFSKRGNALDGTLTLGNVPPS
                     RNVTLEDIMSFDFQPSIPVGQRMSPTKNGLCYIYD"
     subregion       1..33285
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..33285
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     exon            373..1016
                     /locus_tag="CPUR_07423"
     exon            1136..1348
                     /locus_tag="CPUR_07423"
     exon            1475..1593
                     /locus_tag="CPUR_07423"
     exon            5343..5515
                     /locus_tag="CPUR_07424"
     gene            5343..8402
                     /locus_tag="CPUR_07424"
     CDS             join(5343..5515,5741..6384,6493..6705,6835..6943,
                     7913..8402)
                     /codon_start=1
                     /locus_tag="CPUR_07424"
                     /note="CP_07424.1"
                     /product="related to monophenol monooxygenase (tyrosinase)"
                     /protein_id="CCE33499.1"
                     /transl_table=11
                     /translation="MSRVLHCLVWLAIAFSAIASADLDERLMAKLVKEYQTNTIKGLNG
                     SCTQDNVVVRKEWGNLSLRSRREYIAAVKCLAALPSKIDPKLAPGARSRYDDFEATHIR
                     LATKIHGTGFFLPWHRHFVHLYETALRDECNYTDYQPYWDWSKYAYQPVQANPLYDGSD
                     TSMGSNGRYIPGRNGTVQVLPVPEPNPPTLYCPAGTGGGYVERGSFASWILHLGPVLRM
                     FVRNGTPVRPNPRPDGLGYNPRHMIRDFNNTLLQENNSYKIINYMLTKLTNMHAFNSYF
                     YGVPHIGGHLFISGYDNDFYTSPGDPLFYFHHAQMDRIWSIWQSLDFSTRENALDGTLT
                     MDNVPPSRDVTLEDIMSFDFQPSIPVGQRMSPTKNGLCYISPWSCSVEVVGNHDKSEHF
                     LKNIRRYNAALSLTSCSVDGEPRIDLQLHSELYHWQGPLRGKAPAFAQLLFYNTEEATV
                     HRLERPSHSKLDTELLKELHDELIEYNPFVPIYKTAKERLDGELQQSGEGDYQLSLNPQ
                     LGLVMQEGGQTGGGRTCQSWTRLRV"
     exon            5741..6384
                     /locus_tag="CPUR_07424"
     exon            6493..6705
                     /locus_tag="CPUR_07424"
     exon            6835..6943
                     /locus_tag="CPUR_07424"
     exon            7913..8402
                     /locus_tag="CPUR_07424"
     exon            complement(9757..9848)
                     /locus_tag="CPUR_07425"
     gene            complement(9757..16626)
                     /locus_tag="CPUR_07425"
     CDS             complement(join(9757..9848,9916..16205,16322..16626))
                     /NRPS_PKS="Domain: SAT (8-228). E-value: 3.9e-36. Score:
                     116.7. Matches aSDomain: nrpspksdomains_CPUR_07425_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (391-837). E-value:
                     1.3e-133. Score: 437.8. Matches aSDomain:
                     nrpspksdomains_CPUR_07425_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (943-1254). E-value: 2.3e-74.
                     Score: 242.3. Matches aSDomain:
                     nrpspksdomains_CPUR_07425_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1335-1657). E-value: 1.4e-84. Score:
                     276.0. Matches aSDomain: nrpspksdomains_CPUR_07425_PT.1"
                     /NRPS_PKS="Domain: PP-binding (1712-1775). E-value:
                     2.3e-09. Score: 29.6. Matches aSDomain:
                     nrpspksdomains_CPUR_07425_PP-binding.1"
                     /NRPS_PKS="Domain: ACP (1830-1897). E-value: 2.2e-15.
                     Score: 48.6. Matches aSDomain:
                     nrpspksdomains_CPUR_07425_ACP.1"
                     /NRPS_PKS="Domain: Thioesterase (1958-2205). E-value:
                     2.1e-26. Score: 85.6. Matches aSDomain:
                     nrpspksdomains_CPUR_07425_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 201.7; E-value:
                     3.3e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CPUR_07425"
                     /note="CP_07425.1"
                     /product="polyketide synthase that catalyse the
                     condensation of one acetyl-CoA and six malonyl-CoA
                     resulting in formation of nor-rubrofusarin"
                     /protein_id="CCE33500.1"
                     /sec_met_domain="itr_KS (E-value: 3.3e-142, bitscore:
                     463.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.8e-75, bitscore: 242.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.6e-13, bitscore:
                     38.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLQQHILLFHGEYADLVRAVQDLVVRSRTNILLHTLLADAAEVI
                     KQELGAAALYSSDGREGYAGNFEDVLDLAERHADRQCCSHVIEMALLATCQVAELLIAA
                     EADSSILCNNEGLMSIGLGPGLLAAAVAAAAGSTKDILVLGLEAIKVSIHLALAIEETG
                     KNIEDTDGSWSRVVSGFSVEDVETCLSEVNSTLHPLSQAYIGQSHLEEVIIFGPPSTLC
                     KLSTTTTAGFKQALPVILSNSQARAPLYGPHLPPVNTSHIIVDHSSLLGERVLKRPLWS
                     SHCALNPIPVNQTLTETFCMAATQVAHHRSRTDQIIEAVATRFGCTEPGTITVHTLGGS
                     THLASHVRHELEKLGHTVHLGQRLPLPKPFGNGDGATTGTTSGSVSVSRHEIAVVGMAG
                     RFPESDTLDEFWNLLESGQTTHREIPSSRFSVDEFYDPTRTTHNALLARHGCFIKEPGN
                     FDHRLFNISPREALQMDPVQRMLLMTTYEALEMAGYSPPRSRGDGDSNNCTGRHQQSTP
                     QPRIATYFGQTVDDWKTINDQQGIDTHYLPGVNRSFAPGRIGHYFQWAGGFYSIDTGCS
                     SSATALCLAREALASGECDAAIVGGGTLLNAPEWFAGLSQGGFLSPTGACKTYSDAADG
                     YCRGEGVAVIVLKRIADAVRSNDNVLAVVSGAARNCNAGAGSITYPGEEAQVSLYRRVL
                     RQAGIHPHDVGFVEMHGTGTQAGDKVEMRAVQCVFAPGSEKGQQKRHEPLIVGAAKACM
                     GHSEAAAGVVSLIKAILMLQRNLVPPQPGQPFTLNPNLVPLLGNEIQLGNGQAWHRKGD
                     TPRYILVNNFDAAGGNVSLILHDAPSFAQKVPVTTSQLADEQEKGPKHHVVVTSGRTIT
                     ALGANRKNLHKYLTENPKTNLADLAWTTTSRRIHQVNREAYVVTSIGDLCIRLQQPLVP
                     DKVSEPASSVVFAFTGQGSQHLGMGSKLFSASRTFRSLIESYQSLCDVQGLDCQLLNVI
                     SGGSETQWADKPATECDMQVATVALEIALAKYWQGLGFCPTMLIGHSLGEYAALCIAGV
                     LSVGNALALACERATLISSRCPPGDWGMLAIGLPSSTVQRRLRDVAAFATCEVTCFNGP
                     SSTVVGGPMQVLGALESFLKSDDGSSTPVTRLPVQHGFHTSEMDAILDELEASASRLVF
                     HPPTLPVASTLLGRVVQPGEQGVFDADYIRRHTRMPVSFMTAVQSCQTQGLIKNQTFVV
                     EIGPHPTCVGLIKSCLPGLNLHGYPSLRRGRDDEEFISQCLAAAHCAQLPVSWDAFHKD
                     HNNVDQLSLVANLPTYAFDYKEFWHTYKTGALRADAPPPQQDSPSTAGHLSSTCLHSVL
                     KICKQQTEVSATFNVDLKNKDLSKAIGGHVVDGVAICPASIFMDMAYTAALFLGKKSDG
                     PSAKPLLAECELAELNMRSPLVLRDGVEPPLCVVDAVFDKSTKSVSVRFLSQAKNAKGQ
                     TDHGSCIVQMSQAIRPATWEWSRMRPLVKARVASLHASLRPRHVHAMDKSLFYKIFSEI
                     VDYSSAFHAVEEATVASDFHDAAFIIQPQAPAVDLGSYTCSPFIIDALIHVAGFLLNAD
                     VRKPKHEVHIANHIGSLRILGDLTKDSPFLIYATIREQDLRAGTSLCDVYMTNSQDSII
                     AICTDICFKKLDRGFFALLTGSTRAQPPVRSRDVGSRTTWLKGDTTPSSTPSSTSGSEV
                     ASTTRSSISGASDLYDELLDIIAKWSGISVAELQKATSTNFAELGLDSQMSISILADFQ
                     KSTAVELPAAFFTNFPTLDHVRLAIDRQNAEVEEESGRYGTTAGVGEKARVGRTDKQRD
                     SKSSTSEKSVPSSTHLLRLVADALGLQAEDLKPWTKFESVGMDSMMSIRITTSFQQETD
                     IELAAAFFSDHPTVAAAREALDGSPEPNVIEKSPSSYFMPSTSPSIATASTVQLEMQGL
                     SRQGKIDKAISRAVLIQGDSRSRDAPLFMTTDGSGTVESYIHLSALPNGRRIYALESPF
                     VMTPETFDLSIQEMASIFIRAIRKIQPHGPYLIGGWSAGGIYAYEVAYRLTMQGEKISA
                     YIVLDMRAPSLIPTSIVTVDFVEKLGTFEGINRARDLPQDLSIKERTHLMATCHALAQY
                     DAPAFPVDRRPRHVAVVWARLGLDNRQDGPPAAMCRPGLDIGKALADMTLSEFEQYFNS
                     WFYGRREQFGMNGWETLLGDHIAVHCVDGADHFSMMCPPFSTAVGSVVADTVMIAVGDK
                     "
     aSDomain        complement(join(9829..9848,9916..10636))
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_Thioesterase.1"
                     /evalue="2.10E-26"
                     /label="CPUR_07425_Thioesterase.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="2205"
                     /protein_start="1958"
                     /score="85.6"
                     /tool="antismash"
                     /translation="PLFMTTDGSGTVESYIHLSALPNGRRIYALESPFVMTPETFDLSI
                     QEMASIFIRAIRKIQPHGPYLIGGWSAGGIYAYEVAYRLTMQGEKISAYIVLDMRAPSL
                     IPTSIVTVDFVEKLGTFEGINRARDLPQDLSIKERTHLMATCHALAQYDAPAFPVDRRP
                     RHVAVVWARLGLDNRQDGPPAAMCRPGLDIGKALADMTLSEFEQYFNSWFYGRREQFGM
                     NGWETLLGDHIAVHCVDGADHFSMM"
     aSModule        complement(9829..11020)
                     /domains="nrpspksdomains_CPUR_07425_ACP.1"
                     /domains="nrpspksdomains_CPUR_07425_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="CPUR_07425"
                     /tool="antismash"
                     /type="unknown"
     exon            complement(9916..16205)
                     /locus_tag="CPUR_07425"
     CDS_motif       complement(10385..10459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0009"
                     /evalue="2.90E-12"
                     /label="NRPS-te1"
                     /locus_tag="CPUR_07425"
                     /protein_end="2042"
                     /protein_start="2017"
                     /score="38.9"
                     /tool="antismash"
                     /translation="QPHGPYLIGGWSAGGIYAYEVAYRL"
     aSDomain        complement(10820..11020)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_ACP.1"
                     /evalue="2.20E-15"
                     /label="CPUR_07425_ACP.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="1897"
                     /protein_start="1830"
                     /score="48.6"
                     /tool="antismash"
                     /translation="LLRLVADALGLQAEDLKPWTKFESVGMDSMMSIRITTSFQQETDI
                     ELAAAFFSDHPTVAAAREALDG"
     aSDomain        complement(11186..11374)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_PP-binding.1"
                     /evalue="2.30E-09"
                     /label="CPUR_07425_PP-binding.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="1775"
                     /protein_start="1712"
                     /score="29.6"
                     /tool="antismash"
                     /translation="DELLDIIAKWSGISVAELQKATSTNFAELGLDSQMSISILADFQK
                     STAVELPAAFFTNFPTLD"
     aSModule        complement(11186..15337)
                     /complete
                     /domains="nrpspksdomains_CPUR_07425_PKS_KS.1"
                     /domains="nrpspksdomains_CPUR_07425_PKS_AT.1"
                     /domains="nrpspksdomains_CPUR_07425_PT.1"
                     /domains="nrpspksdomains_CPUR_07425_PP-binding.1"
                     /iterative
                     /locus_tags="CPUR_07425"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(11540..12505)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_PT.1"
                     /evalue="1.40E-84"
                     /label="CPUR_07425_PT.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="1657"
                     /protein_start="1335"
                     /score="276.0"
                     /tool="antismash"
                     /translation="STCLHSVLKICKQQTEVSATFNVDLKNKDLSKAIGGHVVDGVAIC
                     PASIFMDMAYTAALFLGKKSDGPSAKPLLAECELAELNMRSPLVLRDGVEPPLCVVDAV
                     FDKSTKSVSVRFLSQAKNAKGQTDHGSCIVQMSQAIRPATWEWSRMRPLVKARVASLHA
                     SLRPRHVHAMDKSLFYKIFSEIVDYSSAFHAVEEATVASDFHDAAFIIQPQAPAVDLGS
                     YTCSPFIIDALIHVAGFLLNADVRKPKHEVHIANHIGSLRILGDLTKDSPFLIYATIRE
                     QDLRAGTSLCDVYMTNSQDSIIAICTDICFKKLDRGFFALL"
     CDS_motif       complement(12089..12118)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0008"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="CPUR_07425"
                     /protein_end="1474"
                     /protein_start="1464"
                     /score="-3.6"
                     /tool="antismash"
                     /translation="GSCIVQMSQA"
     CDS_motif       complement(12332..12403)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0007"
                     /evalue="1.60E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="CPUR_07425"
                     /protein_end="1393"
                     /protein_start="1369"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GGHVVDGVAICPASIFMDMAYTAA"
     aSDomain        complement(12749..13681)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_PKS_AT.1"
                     /evalue="2.30E-74"
                     /label="CPUR_07425_PKS_AT.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="1254"
                     /protein_start="943"
                     /score="242.3"
                     /tool="antismash"
                     /translation="FTGQGSQHLGMGSKLFSASRTFRSLIESYQSLCDVQGLDCQLLNV
                     ISGGSETQWADKPATECDMQVATVALEIALAKYWQGLGFCPTMLIGHSLGEYAALCIAG
                     VLSVGNALALACERATLISSRCPPGDWGMLAIGLPSSTVQRRLRDVAAFATCEVTCFNG
                     PSSTVVGGPMQVLGALESFLKSDDGSSTPVTRLPVQHGFHTSEMDAILDELEASASRLV
                     FHPPTLPVASTLLGRVVQPGEQGVFDADYIRRHTRMPVSFMTAVQSCQTQGLIKNQTFV
                     VEIGPHPTCVGLIKSCLPGLNLHGYPSLRR"
     CDS_motif       complement(13316..13435)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0006"
                     /evalue="2.10E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CPUR_07425"
                     /protein_end="1065"
                     /protein_start="1025"
                     /score="52.0"
                     /tool="antismash"
                     /translation="GFCPTMLIGHSLGEYAALCIAGVLSVGNALALACERATLI"
     CDS_motif       complement(13637..13690)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0005"
                     /evalue="1.50E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="CPUR_07425"
                     /protein_end="958"
                     /protein_start="940"
                     /score="14.4"
                     /tool="antismash"
                     /translation="VFAFTGQGSQHLGMGSKL"
     aSDomain        complement(14000..15337)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.30E-133"
                     /label="CPUR_07425_PKS_KS.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="837"
                     /protein_start="391"
                     /score="437.8"
                     /tool="antismash"
                     /translation="IAVVGMAGRFPESDTLDEFWNLLESGQTTHREIPSSRFSVDEFYD
                     PTRTTHNALLARHGCFIKEPGNFDHRLFNISPREALQMDPVQRMLLMTTYEALEMAGYS
                     PPRSRGDGDSNNCTGRHQQSTPQPRIATYFGQTVDDWKTINDQQGIDTHYLPGVNRSFA
                     PGRIGHYFQWAGGFYSIDTGCSSSATALCLAREALASGECDAAIVGGGTLLNAPEWFAG
                     LSQGGFLSPTGACKTYSDAADGYCRGEGVAVIVLKRIADAVRSNDNVLAVVSGAARNCN
                     AGAGSITYPGEEAQVSLYRRVLRQAGIHPHDVGFVEMHGTGTQAGDKVEMRAVQCVFAP
                     GSEKGQQKRHEPLIVGAAKACMGHSEAAAGVVSLIKAILMLQRNLVPPQPGQPFTLNPN
                     LVPLLGNEIQLGNGQAWHRKGDTPRYILVNNFDAAGGNVSLILHDAP"
     CDS_motif       complement(14348..14395)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0004"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="CPUR_07425"
                     /protein_end="721"
                     /protein_start="705"
                     /score="11.5"
                     /tool="antismash"
                     /translation="FVEMHGTGTQAGDKVE"
     CDS_motif       complement(14588..14623)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0003"
                     /evalue="1.90E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="CPUR_07425"
                     /protein_end="641"
                     /protein_start="629"
                     /score="11.5"
                     /tool="antismash"
                     /translation="SDAADGYCRGEG"
     CDS_motif       complement(14768..14812)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0002"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="CPUR_07425"
                     /protein_end="581"
                     /protein_start="566"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GFYSIDTGCSSSATA"
     aSDomain        complement(join(15827..16205,16322..16602))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_07425_SAT.1"
                     /evalue="3.90E-36"
                     /label="CPUR_07425_SAT.1"
                     /locus_tag="CPUR_07425"
                     /protein_end="228"
                     /protein_start="8"
                     /score="116.7"
                     /tool="antismash"
                     /translation="LFHGEYADLVRAVQDLVVRSRTNILLHTLLADAAEVIKQELGAAA
                     LYSSDGREGYAGNFEDVLDLAERHADRQCCSHVIEMALLATCQVAELLIAAEADSSILC
                     NNEGLMSIGLGPGLLAAAVAAAAGSTKDILVLGLEAIKVSIHLALAIEETGKNIEDTDG
                     SWSRVVSGFSVEDVETCLSEVNSTLHPLSQAYIGQSHLEEVIIFGPPSTLCKLSTTT"
     CDS_motif       complement(16091..16150)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_07425_0001"
                     /evalue="7.30E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CPUR_07425"
                     /protein_end="140"
                     /protein_start="120"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="GLGPGLLAAAVAAAAGSTKD"
     exon            complement(16322..16626)
                     /locus_tag="CPUR_07425"
     gene            18594..19040
                     /locus_tag="CPUR_07426"
     exon            18594..19040
                     /locus_tag="CPUR_07426"
     CDS             18594..19040
                     /codon_start=1
                     /locus_tag="CPUR_07426"
                     /note="CP_07426.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE33501.1"
                     /transl_table=11
                     /translation="MHKDRVNVIHSSFDPVGICVQGNRATSEAFCTVTSEITIDGVGYE
                     LASHMRLLNRLEKSEEGRWHILSMEAIYVRDRLMSTLPGAPVTLRPDLVKQSEEYPGGY
                     RRLALVMLHRGLNPRQDLPHEEDQPRVRRLLEANRNFLNGGGDK"
     exon            21769..21956
                     /locus_tag="CPUR_07427"
     gene            21769..23420
                     /locus_tag="CPUR_07427"
     CDS             join(21769..21956,22195..22838,22955..23167,23302..23420)
                     /codon_start=1
                     /locus_tag="CPUR_07427"
                     /note="CP_07427.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE33502.1"
                     /transl_table=11
                     /translation="MSRVLRYVVLLAVALSAIASANPDERLMAKLVKEYQANTIKGLEL
                     SGYGSSCTPDNIVVRKEWGNLSHQSRREYIHAVKCLHELPSKIDPKLAPGARSRYDDFE
                     AAHIRLAAKIHGTGFFLPWHRHFVHLYETALRDECGYTGYQPYWDWSKYAHRPVHANPL
                     YDGSETSMGSNGRYIPGRNGTVQPLPVPVPNPPTLNCPPGTGGGYVKRGPFAHWTLHLG
                     PVIPMIVRNGWPVKPNPRPDGLGYNPRRMIRDFNNTLLLEKNTYKIVNNMLTNMTDIHT
                     FHPYFYRGPHLAGHLFISGYDNDFYSSPGDPLFYFHHAQIDRIWSIWQALDFSKRENAL
                     DGTLTMSNIPPTRNVTLEDVMSFEFAPSVLVGQLMSPTKNGLCYIYE"
     exon            22195..22838
                     /locus_tag="CPUR_07427"
     exon            22955..23167
                     /locus_tag="CPUR_07427"
     exon            23302..23420
                     /locus_tag="CPUR_07427"
     exon            complement(25001..25249)
                     /locus_tag="CPUR_07428"
     gene            complement(25001..25602)
                     /locus_tag="CPUR_07428"
     CDS             complement(join(25001..25249,25327..25602))
                     /codon_start=1
                     /locus_tag="CPUR_07428"
                     /note="CP_07428.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE33503.1"
                     /transl_table=11
                     /translation="MGFTPTGGPQSNCVGPSHSQSEALTNRSIETYNNGHSYIQHDASG
                     GYSTSSGAFSSLELGMIKSNGDEHRDIPRSLSETIHTPGGDHPLNVQDNDAHRFPPMVT
                     AEQESLAKETASPAENAIHEVQELYSIGVKAGFLQRDDKVQEYLAVMKRIYHRAPYLRD
                     GECQGCCCYSE"
     exon            complement(25327..25602)
                     /locus_tag="CPUR_07428"
     exon            complement(31522..31910)
                     /locus_tag="CPUR_07429"
     gene            complement(31522..33285)
                     /locus_tag="CPUR_07429"
     CDS             complement(join(31522..31910,31993..32054,32261..32649,
                     32801..32883,32978..33014,33133..33285))
                     /codon_start=1
                     /locus_tag="CPUR_07429"
                     /note="CP_07429.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE33504.1"
                     /transl_table=11
                     /translation="MPDHTVTAESLVAVSAVPLGLVIVAVALRFYARRHQKASLLADDW
                     LMLPALITFIGACSCVFYAVHLQAIGYSTFEISKEQRQATLERSGKTQMSLSLVSIICL
                     GCIKASALFFYKRIFCVAGRKAVLNIIIIVLLVIIACWVVIFEFLLAFQCGTHFSAPWD
                     GTQLEYCTRSYPTLQAQATSNLVLDLIVLVLPVYPVIQLQTTRSRKVAIVGIFLLACFS
                     SQSLFLTVGQSAIHRIDPEKYLSRVVFYIILEMGVGLVAVNLPSIWMVFASVAPDALLR
                     SIRSVVSIASFRSGRSRLSRERHEPEPLGSRASSSSILPFSSTGNKIVVGAPYELKPQS
                     PVTDEFEPIPLAGDHATRLAKTQYSICKET"
     exon            complement(31993..32054)
                     /locus_tag="CPUR_07429"
     exon            complement(32261..32649)
                     /locus_tag="CPUR_07429"
     exon            complement(32801..32883)
                     /locus_tag="CPUR_07429"
     exon            complement(32978..33014)
                     /locus_tag="CPUR_07429"
     exon            complement(33133..33285)
                     /locus_tag="CPUR_07429"
ORIGIN
        1 atggcactct cggcaattgc atcggcgaat ccagacgaga gactgatggc aaagctggtc
       61 aaagagtacc aggccaacac catcaaaggt cttgagctat ccagaaatgg ctcatcctgc
      121 acgccggaca atatagttgt ccggaaagaa tggtacgcac ttctttgctt aaattgctct
      181 ggctttcttt ggactatgga gagccttttg cttgtataat gagagcaatg gcttccttgg
      241 cttgcacaag gaagcgggaa agtgtcgcaa ttgcatcaaa agaggagaga agatgaggat
      301 gacagcctta caaaagcttt gacagcgtct ggtactgatg aacgactttc tttgggtttc
      361 accctgccaa aggggtaatc tgagcctcca atcccgtcag gaatacatcc atgccgtcaa
      421 atgccttcac gaactgccgt ccaagatcga tcccaaattg gcacccggtg cccgatctcg
      481 ctacgacgat ttcgaagcca cgcatatacg gctggccacc aagatccacg gcacgggatt
      541 gttcctaccc tggcatcgcc actttgtcta tctttatgag atggcgctcc gagacgaatg
      601 tggctacacg ggctaccagc cctactggga ctggtccaag tatgcctacc aacccataca
      661 tgcgaatcct ctgtacgacg gctcaaaaac ttcaatgggt agcaatgggc ggtatatacc
      721 tggccgcaac ggcaccctgc agaccttacc agttcccggg ccgaatcctc ccgcactgta
      781 ttgtcctccc ggcacgggag gtggctatgt cgagcgcgga cccttcgcct cctggacatt
      841 gcatctgggg ccggtcattc ccatcaatgt ccgcaatgga tggccagtca ggccaaatcc
      901 ccgacccgat ggcctgggat acaacccgcg tcgtatgatt cgtgacttca acaacacgct
      961 gctgcaggaa aataacagct acaaaattgt caacgacttg ctgacaaaca tgacgggtaa
     1021 tcgcccccta ttcatatttt tagcgtccat ttttgagaaa aagaaggaga gagagatgga
     1081 aggcgatcga gttcgtgatg gattctctca ttgacttaca ccgtttgttg gctagacatc
     1141 cataccttcc acccctactt gactcagaag ccacacctcg gaggccattt cttcatttcc
     1201 gactatgaca acgatttcta tacctccccc ggcgatcctc tattctactt tcatcatgcc
     1261 caggtagacc gcatctggtc catctggcag gcgcttgatt tctcgaaaag aggaaacgcc
     1321 ctggatggga cgctcacttt aggcaatggt aagtttccat gtgtaaacac gggtatggga
     1381 ttcaaggctc ggcacgtttt ctgcataagt tcaccaacgg caactcgaag tcgaaaagcc
     1441 attcgaattg caataaagct cacccgtttt ctagtccccc cttccagaaa cgttacactc
     1501 gaggacatca tgtcctttga ctttcagcca tccattcccg tcggacagcg aatgagccct
     1561 accaagaatg gactgtgcta tatctacgat tgatacggaa attggagtaa ggattctgcc
     1621 gtgtgcacaa gcggtaactg ttactgccgt ggcgaataag ccggaacccg agccgatggg
     1681 catgacctgg tgccacttgg gccatcgttg tcggacagga tagatgaatc cgcttcagcc
     1741 cgcctatctg taacaagggc ctcagcatgg ggacttggaa ttgatgaaaa gatagcattt
     1801 cagaatacaa taatagattt tggctcttca agaatttctg ggactttttc ttcttcctct
     1861 gaagactgag ttgagtcctt gggaagtttg agttcttata aacaagaacg tcggacaaac
     1921 agaagtgcct gaggccttgg aatttctttt gcacgcactt cagctccgtc gggcgccatc
     1981 gcagctcgct atgcgatgtc agttctcaat ctcacgacgg gcgtcgtcag gcgtggtggc
     2041 tcttgggcct tggctgaggg ctcacaatgt caatgtgtga attttgcatc tgacccacaa
     2101 ggccatgtcg gtgatgagac ggtggcattg gcgatcggaa tgccattcac cgacatccag
     2161 tgatgagaat atcctaaatg ttcagacttc aggacacccg cgccacaagt gaggaatttt
     2221 gcacagtcac cagtgaaatc acgattgatg gtgttggcta cgaacgtcga actagcctcg
     2281 cgcatgcgcc tctggaacct ttgttacatg tactgtaaaa gtctaaagaa ggcagatggt
     2341 acatacatac tgagcatgga ggccgtctat gtcagagacc gtgatgagta ctctcccggg
     2401 agtcgggact cggaagcgcc tgtaaccttg aatcttgagg cctgacctgg tcaagaaagg
     2461 tggagtgtag ccagggcgtt ataacttatc acagaacggc tcttgtgatg ctacattggg
     2521 gctcaaaccc gcagcaagat cagtcactgt caagactcaa gggtgcggcg tttgttcaaa
     2581 ctttcctgga gccgagtcgg agttttctca atggcggcga agacggccga agacggccga
     2641 agagacagcc gcagacagat attacctaga ccctaggcag tcagtcttat ggctcttgag
     2701 caaacaatcg tctcgtagac caaggcatgt tttttggggg caggttttcg tctcttgtaa
     2761 gttgcagttt tctgattgga agtcctgggt ctatcacgca tgactccatg agacatgact
     2821 ctggtgcgac tacaatgtca aatgcgagaa aagcgtacgt agaaggaagt tcaagtcatc
     2881 agcaaactcc agacttgctt tactaaaaat tagttttaaa ggatctctgt cgggggagag
     2941 tgcttggcac cgacgaggct gtggccgctg tcgtctgtcc cgccctggcc tgcagggcgc
     3001 ctgaagtgag ttgcataatt ccgaggttcc aaggagccaa cttttcggaa ttagttaggt
     3061 aggtatgtac ggagtactcc gtacaacaag caaagttcgg atgtcattcg cgatcggcgt
     3121 ggccgctagc cgttcatgct cccgttcggg acccgggtcc atcgtgtgac ctgtcacctg
     3181 gaccaatcca ctgcctcaca gaacacagaa gagagctatg cactaggcac ctaggtatgc
     3241 agggagagag ccattacata ggttacaggt atacgatatt caggttcatg tcttgtctta
     3301 ttatcagctt cagcattgtg cccgaggccg ttctgttgga atgccgcatg cgccgtcgac
     3361 cacttgagcg tcccccaggg gttagtggca cctttatatt ttgcgtgcaa ttaggtacgt
     3421 gtttggcctt tccgatcttt tgatgaacct tctcatcatg gtcccaaaca tctgattcga
     3481 aaagtttgta aagccggtgt atcgtaacat taacaacctc gacggttcca agtggttgac
     3541 gaatgagagg tcgaaaggct tttacacact ccgtacggag tacatgcccg ctgattatgc
     3601 ccagcctccc cggcaagcca aactttgaag ttgtgctatt ctcagctgcg ggctactccg
     3661 tagatccgtc gctccttgta agttgttgtc attgctcttt ttgcatctct ctttctgctg
     3721 agccgatcgg cggtagcatt gagaagttgg gaacgtgagt tgaaacaaaa aggattgttc
     3781 acccctacca cctcagctcc cacctcccat ccttggaaag aacggcgagg agaggatgaa
     3841 aggaaatctg ctttcccgtt gcagcttgca tcatgcatga tacatacatc gattgcataa
     3901 actaccgaca tactgccctt tgagttccga gacatgcata ggcgattgag attgatcact
     3961 aatctgtacc gatcttgaca cgttccgggg cccgaaaggc gcgtggtgtg cgtgtggtct
     4021 tctttctttg tcctctctct cgcatgcgac atgatgcctt ggccaaaact ggggtagaaa
     4081 tacaaggtga gtctatccaa tttaaataac ctttcaactc aaatgctggt ggccgatcct
     4141 tccacatagc aaggcattgc tatgtaccta acataggtat acggctgtag gcgcggatgt
     4201 ccttcgcgcc tttgggacat cgcatctaat agttgtgaat caagagcgat tgaaacagta
     4261 acgatatcga agagttgaca aaaaaaagac aagtgattct gaaggagtga gacaatggat
     4321 catggatgtg ctgtagcctg tagcctgtca gacggtggtc tttaaacttt tcgttcgctt
     4381 acaaggaact acgtcagtgg aaggatcata acgaatttac ctatatactc cgtaggaacc
     4441 gcaccgaatc accgaatctg tcaggtccgc gtgcacgaat caaaagccgc atcgagctta
     4501 tgtatcattg atcaatcgca aggattcgca acgcatttgc tgaggagcgg gggctacatg
     4561 gctttgtaat cgttatagag ggcagctctg tgtgtgacac ggcaagtgta ggtagaacat
     4621 ctctcgctct gattattgta acttgttgat ctcattccaa aagagaggtt tatatctccg
     4681 acaaacgacg cgcctgagca cgccaagctg atcgtcgaga aggaaaatct ctgcagatgc
     4741 gtggaatccg catacctggg tgttcataga tctcccgcgt gcctaaataa ttcccagcat
     4801 cctgaaacgg gatacacaat gcgcctcgta tttttttcat ctccttcctc ttcccatcca
     4861 atcattttag agacgatgtg gcgaagttgt ctctcctatt agtatctgtg tgagccaaag
     4921 atttaacaca agatggaacg aagttctaga acctaacgaa aaagacgggt aacagggaca
     4981 gatggcttag cattgcgaag cgcaggggag aagaaaagga agccatcatc aaaagtgggt
     5041 ctctgagaat gccttccagg tatttcttaa atccttcctt cttacagctc gcaacggacg
     5101 aaagactacc gttccggtat aatattggct ctagttttgc catttggctt tcttggagtt
     5161 cggtatttag agttctttct gcccatccct cagcagcgag tttgggaatg gaacggatgc
     5221 ctgcaacatt cgcatcacta ccaactacat aatcggttcg cgatcctagc cgacctcctt
     5281 caaacactgc atcgaaggaa gaaaagcacg catcgcatgt atattgaaga aaaagatata
     5341 cgatgtctcg ggtcttacat tgtctggtgt ggcttgccat tgcattctca gcaatcgcat
     5401 cggcggatct ggacgagaga ctgatggcaa agctggtcaa agagtaccag accaacacca
     5461 tcaagggtct aaatggctcc tgcacgcaag acaacgtagt tgtccggaaa gaatggtacg
     5521 cacttcttcg ccttcaatat ctttggactg tggaaagcct tttgcttgta taatgagagc
     5581 aacagtctgc gcagggaagc aggaaagcgt ctcaatcgca tcagactgca gagaaggggg
     5641 gaagaggagg atggtgggcg atgaggcaaa ctccctccga aaacttctgc agcggactgg
     5701 tactgatgaa cgattttctt tgggtttcac cctgccaaag gggtaatctg agccttcgat
     5761 cccgtcggga atacatcgct gccgtcaaat gccttgccgc actgccgtcc aagatcgatc
     5821 ccaaattggc acccggtgcc cgatctcgct acgacgattt cgaagccacg catatacggc
     5881 tggccaccaa gatccacggc acgggattct tccttccctg gcatcgccac tttgtccatc
     5941 tctatgagac ggcgctccga gacgaatgca actacacgga ctaccagccc tactgggact
     6001 ggtccaagta tgcctatcaa cccgtacaag cgaaccctct ttacgacggc tccgacactt
     6061 caatgggtag taatgggcgg tatatacctg gccgcaacgg caccgtgcag gtcttgccag
     6121 ttcccgagcc gaatcctccc acactgtatt gtcctgccgg cacgggaggt ggctatgtcg
     6181 agcgcggatc ttttgcctcc tggatcttgc atctgggacc ggttctccgc atgtttgtcc
     6241 gcaatggaac gccagtcagg ccaaatcccc gacccgatgg ccttggatac aacccgcgtc
     6301 atatgattcg tgactttaac aacacgttgc tgcaggagaa taacagctac aaaattatca
     6361 attacatgct gacgaaattg acgagtaatg actccccccc tttgtagtca tagcgtcaga
     6421 agaagaaggg aaacgggagg acatcgggtt tatgagatat tctctcacta acttacaaca
     6481 tctattggct agacatgcac gccttcaact cctactttta tggcgtccca catatcgggg
     6541 gccatctctt catctccggc tacgacaacg acttttatac ctcccccggc gatcctctat
     6601 tctacttcca tcatgctcag atggaccgca tctggtccat ctggcagtcg ctcgatttct
     6661 cgacaagaga gaacgccttg gacgggacgc ttactatgga caacggtgag tttctgtgtg
     6721 taaacatgcc gcacgggttg aataaatcaa gactcggcac atttaattca ctcacctatg
     6781 gcaatccgaa atcggaaagc ctcgcgaatc gcaaaatgct gacccgtttt gtagtccccc
     6841 cttccagaga cgtgacactc gaagacatca tgtcttttga ctttcagcca tccattcccg
     6901 tgggacagcg gatgagccct accaagaatg ggttgtgcta tatgtacgat tgatgatttc
     6961 atgtggcggg gaatcggaat tggaataagg agggccgttc gtttatactg cactctctag
     7021 cctcgggtgt gtctttttgc tttgcttctt ggcgctccat gggttcgttc tgtagcatag
     7081 ctttgtcttc atcggcaagt ttattttgct cgacgttcac gctccccatt tatagacttt
     7141 tcttcagaac gcggttatcc cctcaaagtt ggacacttca tgtcgatata gcttgaatgg
     7201 ctcagattgc ctgaatcaga cactcgcttg actgcaagtg tattcatctt ccatatgtgt
     7261 gatttcatca tgacaaatgc tgtacaccat ttttgtattg tcgtgcagag agaggtgtga
     7321 cggacctcta aactcaaaac tccatcgacc acgaaggccc aaggaagatg aaagtgcggt
     7381 gaagtaggcc aaatgtcgtc tttcgtgtgc cccatcttgc aaagtccagc tcgaaatacc
     7441 acgtctcgat gacccccttc aacgtgcgtt gctactcgtc tacggcaaaa gccatgtgcg
     7501 agcgtgtagg gcccgtacag gtgccagccc gttcagggtt caatctcact tcgactcagg
     7561 cggcatgacg gcctgcgggc cgggcctggt ccacgaaacg aacggcccgc gtggagtttg
     7621 gcaacagggg aacgaggctg gaggcaatgg cgcgagattg ctttccgacg tgtatgacgc
     7681 aaatgctgtg agatggaata gcatggctga tcgaaagaag aaagaaaaca ggatgcaaat
     7741 gcaatggact tggggatcct ttgcaccatt acaggaatcg atattcctct ccatgtgcca
     7801 tgatttcgaa ctagtaggtc ccccagcccc agagcgcaca gcatacatag cagttgagcg
     7861 aaggccggag cctggccccg cgggggatca gagggccttg ccagtggtat agctcgccgt
     7921 ggagctgcag tgtggaagtg gtcgggaacc acgataagag cgagcacttt ctgaagaaca
     7981 ttcggaggta caacgcggcc ttgagcttga cctcctgctc cgtcgacggc gaaccgagga
     8041 tagatctgca gctccacagc gagctatacc actggcaagg ccctctgcgg ggcaaggctc
     8101 cggcctttgc tcagctgcta ttctacaaca cggaggaagc gactgttcac cgcttggaac
     8161 gaccgagcca ttcgaaattg gacacggagc ttctaaagga gctccacgac gagctcatcg
     8221 agtacaaccc gttcgtccct atctataaaa cggccaagga gcgcctggac ggggagctcc
     8281 agcagtcggg cgagggcgac taccagctgt cgctgaaccc gcagctgggc ttggtgatgc
     8341 aggaaggggg gcagacaggc ggcgggagaa cctgccagtc gtggacgagg ttgcgggtgt
     8401 gatccccgac gagttggacg cgcctggcaa gcgggacgtg atcggtccct cgtctcgctc
     8461 atcgacatct tgctcgtcga gtggttcgag acgccgctta ggggaacgtc gattgtcccg
     8521 tttcacctac gggcacgtta gtagggggag ctcgaacccg cgtccaagtc gcgaacgtac
     8581 cttgcacggc gcacacgcgc gaaatctctc accatgtgca tcatctagcg gattttcaat
     8641 gagaagtcag tgagacgacg ctacttatta cggcacctag agcacaaaag gcaaagggac
     8701 cgagttggca gtcgaagtct cctccacccg cacagcagtg gtgtcctccg ccgcccgcga
     8761 tgcagaagcc gttgcctccg ttgcgggcct tgcaggcgaa gagttcatct tgacgtgatg
     8821 gttgggagaa catgggacgg attgatgatt gatggtgaaa gtacctatga tgaatgaggc
     8881 tgcgcggagc ttgcataact tcgcatgcta accgcagcat attttgcaca aattttgccc
     8941 acattccagg ggtattaggt aatcattggt caaaacatcg tcaaaactta tccacttgga
     9001 actcgtacct agctgtttgt ctcgtgtcaa agttctgtac gcgcaggccg cgtttctcgt
     9061 actccgtgat tctcacgatg cctatgcttc cccgataata ataaaaaatt actccgtatt
     9121 attccagtaa catgtacgca atggacactt cttctcccga ttccgacaca gagggcctct
     9181 cctaccagac gattccgaca cggagggcct ctcctaccag accgattccg acgaaaccca
     9241 cggtacggaa cctctacagc cgagacttcc agcgaatatg gatttgttac gtacccggat
     9301 gaagaagcgt tccatccttg gggctcgcct gaacttgcac cttcacgcga ggccaccgcg
     9361 gaatacgccc ggaaagcctc tgaacagtca aggtgactat ttccaggaaa gcgtccgact
     9421 caaaaagggc aattttcacc accttctaca gcgattacga gccaatacaa gcttgacgag
     9481 aatcgggaga agaagtgtcc attgcgtcgg aatcggtttg gtaggagagg ccctccgtgt
     9541 cgaattcggc agaagaagtg tccattgcgt aagtgttgcg gattaataat ttttttatta
     9601 ttatcgggga agcataggca tagtatcaag gattcaagag aaagggcggt ctgcgcgaac
     9661 aaaactttga cacgagattt atgtatgtac cttctaagtt ctagcttctg acgcaacttt
     9721 ccgtcgaatt cgattttcct ccacctttga gcacgtttat ttgtcaccaa ccgcaatcat
     9781 cacggtatcc gcgacaacag atcccacggc tgttgagaac ggcggacaca tcatggaaaa
     9841 gtgatctgct agcgtgaaaa cgccggtcag tgtgcgcact caattgatag caaatattct
     9901 caagttaaca catacctccg tccacacaat gcacagcgat gtggtcaccc agcagggttt
     9961 cccatccgtt catcccgaat tgttcacgtc gaccgtaaaa ccacgagttg aagtattgct
    10021 caaactccga tagcgtcatg tcggccaatg ccttgccaat gtcgagtccc ggccggcaca
    10081 ttgctgcggg aggtccgtct tgtcggttgt ctaggccaag tcgtgcccac acgacggcta
    10141 catggcgcgg tcgacgatca acgggaaagg ctggggcatc gtactgagcc agtgcgtggc
    10201 atgtggccat cagatgcgtt cgttccttga tcgatagatc ctgcggcaga tcacgcgctc
    10261 gattgatgcc ctcaaaggtg ccaagctttt ccacaaagtc tacagtaacg attgacgttg
    10321 ggatgagaga aggggctcgc atgtcgagaa caatataggc cgaaattttc tcgccttgca
    10381 tggttaatcg gtaggctacc tcgtaggcat agatgccgcc cgccgaccag cctccaatca
    10441 gatacggccc atgtggttgg atcttgcgga tggcacgaat gaagatggac gccatttctt
    10501 gaatagacaa gtcaaacgtc tcgggtgtca tgacaaacgg tgactccagc gcgtatatcc
    10561 ggcggccatt gggcaacgcg ctgaggtgga tatatgactc taccgtccct gatccatcgg
    10621 tagtcatgaa caaaggagca tctcgggagc gcgagtcgcc ctgaatcagg acagcccggg
    10681 agatggcttt gtcgatcttg ccctgtcgac ttaagccttg catctctagc tgaaccgtgg
    10741 aagcagtggc tattgagggc gaagtacttg gcatgaaata tgacgacggc gacttctcaa
    10801 tcacatttgg ctctggcgat ccatccaatg cttctcgcgc agccgctacc gttgggtggt
    10861 cagaaaagaa agcagccgcc agttcgatat ctgtctcctg ttggaaggaa gtcgtgattc
    10921 ggatactcat catggagtcc ataccaacag actcaaactt ggtccaaggc ttgagatcct
    10981 cggcctgaag gccaagggca tccgcgacaa ggcgaagcag gtgtgtactt gatggtacag
    11041 acttctctga tgttgacgac ttgctgtccc tttgcttgtc tgtccgtccg acgcgagcct
    11101 tttctccgac ccccgctgtc gtgccatatc tgccactctc ttcctccacc tcagcatttt
    11161 ggcgatctat tgctaggcga acatgatcta gggtgggaaa gttggtaaag aaggcggcgg
    11221 gcagctcaac ggccgtggat ttctggaagt cagcgagtat tgagatgctc atctgagagt
    11281 cgaggcccag ttcagcaaaa tttgtgctcg tggccttctg taactcggcg acactaatgc
    11341 cactccactt ggcgattata tctagcaact cgtcgtagag atcactggcc cccgaaatgg
    11401 aagaccgagt tgtcgaggct acttctgacc cggaggtgga agaaggggtg cttgaggggg
    11461 tcgtatcacc ctttagccat gtcgttcttg agccgacgtc tcgacttctg accggcggct
    11521 gtgcccgcgt cgatcccgtc aacaaggcga aaaagcctcg atctagcttc ttgaagcata
    11581 tgtcggtgca aatggctatg atactatcct ggctgtttgt catatacaca tcgcatagac
    11641 tggttcccgc tctcaggtct tgctcccgaa tggtggcgta aatgagaaat ggactgtcct
    11701 tggtgaggtc gccgagaatg cgaagcgacc caatgtggtt cgcaatgtgg acctcatgct
    11761 tgggtttccg aacgtctgca ttcaggagaa agccggccac gtggatgagg gcgtcgatga
    11821 tgaaaggact gcaggtgtag gagcccaagt ccacagccgg ggcctgtggc tgaatgatga
    11881 aggcagcatc atgaaagtcc gatgccacgg ttgcctcctc cacagcatgg aaagcgctag
    11941 agtaatcgac aatttcggaa aagatcttgt aaaatagcga tttgtccatc gcatggacgt
    12001 gccgcggacg cagagacgca tgcaaactcg ccactcttgc cttcaccaaa gggcgcatgc
    12061 gcgaccattc ccaggtggca gggcgaattg cttgactcat ttgcactatg caggaaccgt
    12121 ggtctgtctg tcctttggca ttttttgctt gggaaaggaa acgcacggat acacttttgg
    12181 tcgacttgtc aaaaacagca tctacaacgc aaagcggcgg ctcgacgccg tctcgcaaga
    12241 ccaacgggga gcgcatgttc aactccgcca gctcgcactc cgccagcaac ggcttagcag
    12301 aagggccgtc gctcttcttc ccaaggaaaa gtgccgccgt gtaagccatg tccatgaaga
    12361 tactggccgg gcaaattgcc acgccatcaa cgacatggcc gccaatggcc ttggacagat
    12421 ctttgttttt caaatcgaca ttgaaggttg ccgaaacttc ggtctgttgc ttgcaaattt
    12481 tcaggacgga gtgaaggcag gtggaggaca aatgaccagc tgtggatgga gagtcttgct
    12541 gtggtggtgg tgcatcagca cgcagcgcgc cggtcttgta agtgtgccaa aattccttgt
    12601 aatcaaaggc atatgttggc aaattagcaa ccaagctcag ttggtctaca ttattgtggt
    12661 ctttgtggaa ggcatcccac gataccggca actgtgcaca gtgcgcagca gcaagacact
    12721 gggagatgaa ctcttcatcg tcgcgccctc gcctcaggct aggatacccg tgcaaattga
    12781 ggcccgggag gcaggatttg atcaatccta cacaagttgg gtgtggtccg atctcgacga
    12841 cgaaggtctg gttcttgatc aggccctgcg tctggcaaga ttgcactgcc gtcatgaagc
    12901 tcaccggcat gcgagtatgg cggcggatat aatcggcgtc aaacacaccc tgttcgccgg
    12961 gctggaccac acgcccgaga agagtcgatg ccaccggaag agtgggcggg tgaaatacca
    13021 agcgagatgc ggaggcttcc aactcgtcca aaatggcatc catctcgctg gtgtgaaagc
    13081 cgtgttggac gggaagacga gtgacgggcg tgctgctgcc gtcatctgac ttcaagaaac
    13141 tctccaacgc gccaaggacc tgcataggac cgcccacaac ggtgctggaa gggccgttga
    13201 agcaggtgac ttcacatgtt gcgaatgccg ccacgtctcg caggcgacgt tgaactgtgc
    13261 ttgacggaag cccaatggcc aacatacccc aatcccctgg gggacatcga ctcgaaatga
    13321 gggtagccct ttcgcaagcc aaggcaagag cattgcccac ggatagcaca ccagcaatac
    13381 acagggcggc atactcgccc aagctgtgac cgatgagcat ggtgggacaa aagccaagcc
    13441 cttgccagta ctttgcgaga gcgatctcca gggcaacagt ggcaacttgc atatcgcatt
    13501 cggtagcagg cttgtccgcc cattgcgttt cgctcccgcc gctaataaca ttgagcaact
    13561 gacagtcgag tccctgtacg tcgcaaagac tctggtacga ctcgataaga cttcggaacg
    13621 tgcgagatgc actgaatagc ttgctaccca tgcccaggtg ctgactcccc tgacctgtga
    13681 aggcaaacac gacagacgat gctggctcag agactttgtc gggcaccaaa ggctgctgca
    13741 atctgatgca gagatcacca atagacgtca ccacgtacgc ctctctgttc acttggtgga
    13801 tccgtcgcga tgtcgtggtc caggcaagat cagcaagatt ggtctttgga ttctcggtga
    13861 ggtacttgtg cagattcttc ctattggccc caagggccgt gatagtgcgg ccagaggtta
    13921 cgacaacgtg gtgcttcggc cccttttctt gttcatccgc cagctgagat gtcgtcacgg
    13981 gcaccttctg ggcgaacgac ggggcatcat gcagtatcag gctcacgttc cccccagcgg
    14041 cgtcaaaatt attgacaagg atgtagcgag gagtatctcc cttgcgatgc cacgcttggc
    14101 cgttgccgag ctggatctcg ttgcccagca ggggcaccag atttggattg agcgtgaagg
    14161 gctggcccgg ctgaggagga accagattgc gctgtagcat caagatagcc ttgatcaatg
    14221 agacgacgcc cgctgcggcc tcgctgtggc ccatgcaggc cttggcagcg ccaacgatca
    14281 gcggctcgtg tcgcttctgc tgcccctttt cggaaccagg ggcaaagaca cactgtacag
    14341 cacgcatttc caccttgtcg ccggcttggg ttcctgtccc atgcatttcg acgaagccaa
    14401 cgtcatgcgg gtgtattccg gcttgtcgga ggactcgacg gtagagagag acctgggcct
    14461 cctcgccagg gtacgtgatg gagccggcgc cggcattgca gtttcgggcc gcgccggata
    14521 cgacggcgag aacgttgtca ttcgaccgaa cagcgtctgc aatgcgcttg agaacaatga
    14581 cggcgacacc ttcacctcgg cagtatccat cagccgcgtc agagtatgtt ttgcatgcac
    14641 ccgtgggcga gagaaaccct ccctggctca ggccggcgaa ccactcgggt gcattgagga
    14701 gcgtgccgcc accgacgatg gcagcatcgc actcacccga ggcaagcgcc tcgcgggcaa
    14761 ggcagagggc cgttgcgctg gatgagcaac ccgtgtcgat gctgtagaag ccaccggccc
    14821 attggaagta gtgcccgatt ctgcctgggg cgaagctgcg gttcacccca ggtagatagt
    14881 gggtgtcgat gccttgctgg tcgttgatgg tcttccagtc gtcgactgtc tggccgaagt
    14941 acgtggcgat tcggggctgc ggtgtgcttt gctgatggcg gccagtacaa ttgttgctat
    15001 caccatcacc acgacttcga ggtggcgagt agcctgccat ttctagagcc tcatacgtcg
    15061 tcatcaagag catgcgctgc acagggtcca tctgcagtgc ctcccgcggg gatatgttga
    15121 acagccgatg gtcaaagttc cccggttcct tgatgaagca cccatggcgc gccaggagag
    15181 cattgtgcgt ggtgcgtgta gggtcataaa attcatcgac gctaaatcgc gacgagggga
    15241 tttccctgtg cgttgtttgc ccagactcga gaagattcca gaattcgtcc agcgtgtcgc
    15301 tctcggggaa tcgaccagcc atgccgacta ctgcaatctc atgtcgcgac accgacactg
    15361 accctgacgt tgtgccagtg gtggcaccgt caccgttgcc aaagggcttc gggagcggta
    15421 gtcgttgccc taggtggact gtatggccaa gcttttccag ttcatggcga acatgggatg
    15481 caagatgcgt cgagccgccc aaggtgtgga ctgtgattgt gccgggctct gtacacccaa
    15541 atctcgtcgc gacggcctcg ataatctgat cagtccgtga acgatgatgg gcaacctggg
    15601 tagccgccat acaaaatgtt tcggtcaatg tttggttgac cggaattgga ttcaaagcac
    15661 agtgagaaga ccatagtggc cgtttcaaga ccctttcacc gagcagcgaa gaatgatcga
    15721 cgatgatatg gcttgtgttg accgggggca gatgtgggcc gtacaaggga gctcgggcct
    15781 gtgagtttga caggatgaca gggagggcct gtttgaagcc ggctgttgtg gtagtcgaga
    15841 gcttgcacag ggtagaaggc ggtccaaaga tgataacctc ttccaagtgt gattgtccaa
    15901 tgtatgcctg gctgagaggg tgcagcgtgg agttgacctc ggacagacat gtctcgacat
    15961 cttccacgct gaaaccagag acgacgcgcg accatgagcc atccgtatcc tcgatgttct
    16021 tcccggtttc ctcgatggcc aaagccagat ggatggacac tttgatggct tctaagccca
    16081 gaacgagtat gtcctttgtg ctgcctgcag cagcggcaac cgccgcagct aataagccgg
    16141 gacctaagcc gatggacata agtccttcgt tattgcacag gatagatgag tccgcctcgg
    16201 cagctctatt acatcccgtg ccgtgtcagg agtcaggacc actttgagtg cattgcatga
    16261 tccgcgggga gtgggacggc tccgagcctc cgaacaataa agagatatcg cacaaacgta
    16321 catgagtaac tctgcaacct ggcatgtggc caataaagcc atctcgatga catggctaca
    16381 gcattggcga tcggcgtgcc tttccgcgag gtccaaaaca tcctcaaaat tccctgcata
    16441 accctctcta ccatctgagg agtacaaagc agcagcacca agctcctgct ttatcacctc
    16501 tgctgcatcg gcaagcagcg tatgaagcag gatattcgtt ctggagcgca cgaccaagtc
    16561 ctgcactgcc cggaccaagt ccgcatattc gccgtggaaa agaaggatat gctgctgaag
    16621 tttcatttcg gaggaatgct gatccagtct tgcgcgtttg gtaacaggaa tataatgaaa
    16681 acagaaggaa gatgaatagc tcgaccgtct ggtttactca atctccttgc actgttgggc
    16741 tagtaaggag aaggactcta agtctaggac agaatatgcc aagccggtgc atctttatac
    16801 aagagaatat ccaagcttca ggacttggac tgcagaaaac aagtacaagg tagagaatgt
    16861 gcgtgagaca cacgggatgc ataagacgtt ttctcgggcc ctttgtcggg agtcgggact
    16921 cgggagtcgg gacaaatgag gcggtcaggc ggggtgagag tgagggctga caatgaaatg
    16981 agtccgtttc agaagagctg agagaagcat acagtaatcc atccgtggta tggataatgg
    17041 ggatgataat ctgaaatctg agtcatgagc aacccaaccg agaaggcaag gctgttctgc
    17101 tgcggttgta cactcttgct tattttagag cgtgtctcac cgactacttg atctgaatgg
    17161 agcatcaatc actgaatatt tcacgcaggc caagatgggc cggaatcagc aatgcgcata
    17221 tcacggcgtg gcagactgga agcagtgaac gaaggggggg gtgtgttggg caatgggggc
    17281 agggatgcct cattgcctac tgcttgattc ccgcaagcgc atctttgttc tttttttact
    17341 ttcgctctct ccttcacagt ttattttctg ttttccagta gtaaggcaca acttacaagt
    17401 tgaagtaatc aggcatggtg tggtagaaca agagcgatgg ctgatggaaa cacatggcgg
    17461 agtcatctgt gtcatgctca agtgtcggtg cggcacgaag ggttgtaact tgttcttccc
    17521 tggtttgttt ggggtcggaa tgcagggcta tgattcctcg gacctctaca tagttctccg
    17581 gattcctctt actcaatatt atggccgtgt tagaacccca tcatttgagc accacgttac
    17641 catcgggaca tggcctacca tcacttttgt aattatagct acggagtacc gactactaac
    17701 gacgtgatcc tctttgtcgt tccctggaat tgtgtcttca ctttatagcc tatacatgca
    17761 cactgatcag tgatgtaatt ataggctcgt taagctagag agaacggcgc tgttgcctac
    17821 atggccgtca ttcctgtcta cctagtctca acgtggttga gaggtttagg gcatgggcag
    17881 ggggcaggac tgaggagcct ggtactatgt atgtattacc aataatacca gcctcaacgg
    17941 gacgtgtcaa tgattccaga accaggcgtt acatgcacga tgcgagttag atgcaagctt
    18001 acctattcaa cacttgacat aaatgtgatg tcacctccca tctcttcatt tccatgagaa
    18061 tgtttcttgt ggccttcttt catcgtttct ttgtccggac cccgttttta tcatttcttt
    18121 gcttctttga catttttgac gagtggatgt acagagtatt ttcccacaaa gagcttccat
    18181 tccgcaccga gagcaagata acgacgagtc acgactcacg atgatagcgg acacgaaggt
    18241 cggcttagat gtggaagctg atattgcaag aattgcatat ttgctcaaaa gcgagcgatt
    18301 caatcgggac acggcacgat ggcaactgtg ccgcttatcc ttccatccgg atgtgtccaa
    18361 gacatatatt aacgtatcat ggttagtgga ttcatcattc atcattgctc gtctctgctg
    18421 ttaatgattc tctgagagaa gacaagaaaa agggtaaccc ggtggggtga tggagaagtc
    18481 tgaagaatcg gtggaggaca taaacgcata agtctaaggt cgctgctaat acaggatctt
    18541 tttcttccag gtaccaaggc caggttgacg acttcctgaa gcagtcttcc aagatgcaca
    18601 aggacagagt caacgtcata cactcttcct ttgatccagt gggaatatgt gttcagggca
    18661 accgagccac gagtgaggca ttttgcacag tcaccagtga gatcaccatt gacggtgttg
    18721 gctacgaact agcctcgcac atgcgcctct tgaaccgatt ggaaaagtct gaggagggca
    18781 gatggcacat actcagcatg gaggccatct acgtcagaga ccgcctgatg agtacgctgc
    18841 cgggagcgcc tgtcacgttg aggcctgact tggtcaagca aagtgaggag tacccagggg
    18901 gctatcgcag attggctctc gtgatgttac atcggggctt gaatccgcgg caagatctgc
    18961 cccatgagga agatcagcca agggtgcggc gtttgttgga agcaaatcgg aattttctca
    19021 atggcggtgg agacaaatag accctagtta gccagttgtg taatatgtat gtactctggc
    19081 aggcaatgtt aatattctcg cagatcgatt gatgtttttg gagacaaggt ttaaatatct
    19141 tgcagtcttt ctggtcgagt ctcgggtcca acacgtatgc gggtgtgacg tgtaataagt
    19201 atgattttaa tgcatgggac ccctaccgac cccaggccca ggggcccatt gacaggccat
    19261 tatcgcacgg caatgggcat gtgtccgatg cgactatttc agatacgaga gaagcttagg
    19321 tatgcagaga aatcaaaagg ttcaaataat tagcaacgtc tagactcctt aagaatctct
    19381 ggcgggagag agtgcttgac acaaacaagg ctgtgtctga tgtcatccgt tcagccctgg
    19441 ccaagcaggg agtggtatgg ttccggtcgg cggttcagtt gcgaaagatc aaggatgagt
    19501 ggtatagttt atgagtgagc actgagctaa gtatgagtag caagaattgt gccttgccga
    19561 ggcaaaattc agaactgcag agtttggatg ttgccgtgac cgctagagcc tggccgttca
    19621 tgctctgtaa gttgttcatg tccatcgtgt gacctcctcc gctgcctcag ggtaccgggc
    19681 agaaggctat acagaccaga ccaacgggag aggagaggcc ttgtaccacg ggcatgagtc
    19741 gtaatgctca ggtccatgtc ttatgactct cgtcttcagc tttgtgcccg acgcattcgt
    19801 gttgcaacgc atcattcgtc gactaggttg gcatctattt tagcggcctc cagtgggctc
    19861 aggttttttt atttttgggc ttgcaatcac gttcccgacg cttttatcag ctagccacgt
    19921 gttggacatt tccgaacttc tcaatgaacc ttctcaccat gcgctctggt tcgaagagct
    19981 gtgaattggt cgcgtgacaa tgtctagcgg gcgctgggcc gtgtcgttgt aaatctcacc
    20041 agacgccaca acacataagg tctttacggg tttggccgaa gagaagtacc tgacctgacg
    20101 tgagcagatt atcctcagcc tctgtcggca agccaacctt ggacttccag ttttctcagc
    20161 tggtgccctc tatccccgtc gctgttattt tagtcatttc tttggtcgag gccgatcaat
    20221 tgggaacccc gtgggccatg catatgtgtg tgtgtgaata cgcccccaat ggcgactgct
    20281 aaccaattga accggcgaac ccccgaagtt ggccttggaa cgaacgatgg actcgagggc
    20341 ttgagcaacg gggatggcag aaaaataggc agcctgcttc ccgttaaagc gccttgatct
    20401 gcgttccgag acatgcatgg gcgattgaga ttgacatgta gtttcaagtt tgaggaaaca
    20461 aatcttgatt cgtttctggg cccgcaatgc gcaagtgctc gcgtgacgtc ttatttctta
    20521 ctttgctctc tcacatgagg ccttggccta cgcggggtag gtagaagtac aacgtgaggc
    20581 ttgaaaaata accacgatat tgaatgctta cctatcgctt agaaataagc gaaagatggc
    20641 ttgaagaatg atacatatcg gtccccatct acgccactat gtattctgat atcaaagaaa
    20701 catacacgag ctgacatgct agagatcaat tcttccagcc gcatcaagtg atgaatcaag
    20761 agccatagct gtgacatgtt taaaggtttc agataatgtg aatcagatat ggatcgcgcg
    20821 tatgacacga gaagtgtaca caacgtctaa cgcatacgga gagaatctct cgcgagtcgc
    20881 tctgattcat ctggatctcg ttacgaaaga gcagtgtatc ccaaatgaag aacacacgta
    20941 agcacgccaa gccaatgtgc agacacacat tctctgcgcc gctgcggatt cgcgtaaaca
    21001 ggtacgcgga gagacccgga ataggcgttc atagatctcc cacgtggcca aataattccc
    21061 agggtcctga atcggaacac aatgcgcctc gtattatttt tttaatctct ctcctttccc
    21121 tagcccaatg atttgcagag atggcgttgc ggtgttgtcc ctcctgcctg tgtcggccca
    21181 atacatgtcg tgtgacggct acatatgggc aatggccata gccgtcacac acagaggctt
    21241 agaacaaagt tctcgaaggg agcagaaaat agaagtcaaa gtgacagtga cgtcgcgctt
    21301 cgaagcctgc caatcttggt tcttctgtac tccgtgaaac tgaagcaatg tgaagcacag
    21361 gggaaaagaa gaagaaacta tcgtcgaaag gtggggtcgc tgagactatc taggcaggta
    21421 gttgtctgtt tctttctcct tatagaaaga ctatcgtttt gatattgatg ttggctctat
    21481 tttcgctgtt tgaatttcgt cgagttcgcc acctaaatat agaggtcctt tcggccattc
    21541 cgcaacagct cttttgacgc catttcgatg tcttcgaatt cggcacttaa atatagaggt
    21601 cctttcgacc attcttcaac agcgcgtttg ggaacgaaac agatgccttg taatatttgc
    21661 attactgaca actcatcgat tcccgaatcc ccgccttcgt caaactcctt caaacattgt
    21721 attgaagaaa gaatcgcacg cgtcgcatat tgaagaaacg gagatacgat gtctcgggtc
    21781 ttgcgatatg tggtcttgct tgccgttgca ctctcagcga ttgcatcggc gaatccagac
    21841 gagagactga tggcaaagct ggtcaaagag taccaggcca acactatcaa gggccttgag
    21901 ctttccggat atggctcatc ctgcacgccg gacaatatag ttgtccgaaa ggaatggtac
    21961 gtacttctcc gtcttgactt tctttggacg atggaccatg agccttctgt ttgtataatg
    22021 agagaaaaat tttgcacaga aaagcaggaa agagtcgcaa tcgcatcaga ggtgacaaga
    22081 ggatgatgat ggcccgtggg cgatgcgcat tgggcgatgg ggcagggtcc ttgcgaaaac
    22141 tttgacagtg tctggtactg atgaacgctt tctttgggtt tcaccctgca aaaggggtaa
    22201 cctgagccac caatcccgtc gggagtacat ccatgccgtc aaatgccttc acgaactgcc
    22261 gtccaagatc gatcccaaat tggcacccgg tgcgcgatcc cgctacgacg atttcgaagc
    22321 cgcgcatata cggctggcag ccaagatcca cggcacgggc ttcttccttc cctggcatcg
    22381 ccactttgtc catctctatg agacggcgct ccgagacgaa tgcggctaca cgggctacca
    22441 gccctattgg gactggtcca agtatgccca tcgacccgta catgcgaatc ctctgtacga
    22501 cggctccgaa acttcaatgg gtagcaatgg gcggtatata cccggccgca acggcaccgt
    22561 gcagccgttg ccagtgcccg tgccgaatcc tcccacgctg aattgtcctc ccggcacggg
    22621 aggtggctat gtcaagcgcg ggccctttgc ccactggacg ttgcatctgg ggccggtcat
    22681 tcccatgatt gtccgcaatg ggtggccagt caagccaaat ccccggcccg atggcctggg
    22741 atataacccg cgtcgtatga ttcgtgactt caacaacacg ttgctgctag agaagaacac
    22801 ctacaaaatt gtcaacaaca tgctgacgaa catgacgggt aatttccccc tccttgtctt
    22861 tttagcgtct gttgttaagc gaagtaaagt agaagagaga cgggaggcga gcgagtttgt
    22921 gatgcatttt ctcattgact tacttgttgg ccagacatcc acaccttcca cccctacttt
    22981 tatagaggtc cacatctcgc gggccacctc ttcatctctg gctacgacaa tgatttttat
    23041 tcttcccccg gggatcctct gttctacttt caccatgctc agatagaccg catctggtcc
    23101 atctggcagg cgctcgattt ctcgaaaaga gagaacgcgc tcgacgggac gcttactatg
    23161 agcaacagta agtttctatt gtaaacacgt acacatttgt gtttatgatc caagactcgt
    23221 cattgttgtt tcactcaccc atgaactcaa agtcggaaag cctcgcaaat tgcaagatgc
    23281 tgactctcat ccattttcta gtacccccta ccagaaacgt gacactcgag gacgtcatgt
    23341 cttttgagtt tgcgccatcc gttctcgtcg ggcagcttat gagccctacc aagaatggtt
    23401 tgtgctacat ctacgagtga tgtgacacgg aaattagaac aaggagggcc atcggtttat
    23461 actgcactcg ttacgcctcg ggtttgtctt tttgcttttt agtcactggt gggcgtttcc
    23521 aatgcttcgt tctgtacagt gtagcgtagc ttcgtctttg tcgacaattt ctttctttga
    23581 cgttcatgct cagcagtttt agactctcct tcgaaacacg atagacagaa gagggtaggg
    23641 gcaagaagaa ggtgagatag acattttctt aaagttagac acttcatgcc catagagctt
    23701 gctcagattg ctgaatcaga cactcgtttg actgcaagtg tattcatcgt ccgagacgtg
    23761 tgatttcgta atggcacatt tcgcatgtgc catttccgta cgggcgtgca gagagagatg
    23821 tggcggactt ctgaccttaa aactcgatcg aacacaaagg gtgttggtac tgcgatgaaa
    23881 gcgacacaaa gagcgataaa gtgcagagaa aatcgctgca acctcttatc ccgacatttc
    23941 catccaccct ggcaagcttc gcacaagctc catcaagcag aaacggtgtg accgcgatga
    24001 aagtgcggcc aagtgcgtca aatatcgctg cgccgcgtct cttctccctg gcctgtccgt
    24061 cggaattgat aagcttcgca gcattcaatc tcacgagcgc tgttttcggt ctcccgtgtg
    24121 tctcatcttg ccgagctcga tgtctgcgaa tgtggttgcc tcgtacagat gccagctcgt
    24181 tcagcattca ttcagcctca cttctcagca ggaggtatgg cggtctggtc cacgaacggc
    24241 ccgcgtggag tctggtaacg agtgagcaag gctgggggca acggcacaag attgcttttc
    24301 agcgcgtata gacgaccaac accatggacg gcacgttgtt tgttgttgag tgagagggga
    24361 tgaggggttg atctgcttcg ccacgttgtc cgaagttgat cgattgcggg gaaagcggca
    24421 agcctcgcga gcgccacaac ttacaagatc cgccacatgg ttagtgtccc caaccgctta
    24481 gctgagggcg tcgactgccg gttgtctgaa tctgctctag tgccgggtcc agtggacggc
    24541 tgtaacgcct gtaacggctg caacttggtg cattcggaat tttggagcac tttgaggtta
    24601 catgctaaga aagccgttgg tgttgagaag ctacgatcaa tgcccattgc caactacgtt
    24661 tcattcacct cgcgcgtgca cctttgcctc atgcgagata ctttgcgaga ggactctggg
    24721 acatttccaa gaagtctttg tgttttctac acgagaatcg ctacgagctc tgctaagtgc
    24781 gcactgcgaa tcatcgcaac ggctcgacaa cgttcaggtc atcaattgat gcaacacgtg
    24841 gacgattcca acttctaggc tgcatacttc cggctgtaat cctcacgatt cctagaagaa
    24901 gagcacgaaa acagttactc ctaataaatg tacactcatc ttcgtttctc cacggccata
    24961 gctaagagct tcgacttcct tctctacgaa ttagttggcg ctattccgag taacagcaac
    25021 acccctggca ttccccgtct ctcagatacg gcgctcgatg gtagatgcgc ttcatgaccg
    25081 ccaaatactc ctgaaccttg tcatcgcgtt gaagaaaccc ggccttgacg ccgatgctgt
    25141 acagctcttg gacttcgtgg atggcattct cagcagggga tgctgtctcc ttggcgagag
    25201 attcctgctc tgctgtgacc attgggggaa atcgatgggc atcattgtcc tgtttttctt
    25261 agcttttcaa gatcctgaag aatacgttat tgaattcggt cctggttttt ttccctggat
    25321 cctcacctga acattaagag ggtggtctcc gcccggcgta tgaatcgtct ccgacaggct
    25381 ccgcggaatg tcgcgatgct cgtccccgtt tgacttgatc atgcctagct caagacttga
    25441 aaaggcgccc gaggatgtcg agtagccacc actagcatca tgttggatgt aggaatggcc
    25501 gttgttgtac gtctcaatcg atctgtttgt gagcgcctca ctttggctgt gcgatggacc
    25561 gacacagttc gactgcgggc cgccggtcgg tgtgaaaccc atgtgccatg gttccagggg
    25621 tagactttcg cttgcgtgag ttaccgctgg tgaatgttta tgtatccagc tcgtcctgta
    25681 gtcgactctg tcgcctatcc cacgaggctc tgtgatgaaa ccgcactgca tcgaggatag
    25741 cggcgacaat aacgatgttg tgctactgac gtcgtctccg gtacagatgg acggtttcga
    25801 ctgattcgaa tgcgatttct tgtgacgtct tcctaaagtc gtgttgttgt acacaaccaa
    25861 gaccaggtat tagcacatgt aacatgtttt attataaata gatgcatgtt gatatgttat
    25921 ttcacgatcg ctgcaagggt ctgttgttgt ttgtgcttgt caggactcag ggttcgtact
    25981 ccaacgctgc tgagattcac ggttctggcg acgccgtctt tcacgaagat cctcaccaga
    26041 ttgctctggc atattcccgt tctcgtacgt atcgagggag taaactgcta aataggaaaa
    26101 aaagaaaagg ataataatgc aagggggaga aagaggacag ccgggggtag aagatccttg
    26161 taatatcttc ttgtcttgtc tcttcttttc tttctctcat tcttaagttg tgtttcctac
    26221 aagatcgacg ggcggtggcg tcgcttcaac aattccaaag taaggtaaaa tgactggaaa
    26281 acaggaagcc gattggctat accaattata gagagcagca gagcttgata gaaaaagcaa
    26341 catgagcggg aaaactggat gacatgtgta attctttcgt cctgtcaaca gagggttgca
    26401 ttttgaatct ccgcctcact tgaagcggca caccaaggag ggtggggagc tcgcgcatcc
    26461 aagccagctt tctgccgtag gtctttctgc cgtaggtaac ttgttggtaa gcaccccttc
    26521 ttgaagcaag ggcagagccg aaagctgtca gatctctgag cgctggaatt gagttttcgc
    26581 ccatcatttc cgacctccgc ctttcgagga gatggcgggc tttgggagtc cggagacctt
    26641 gcaagttgcg ccacgaatgc aggtttccca tctagaatag ctgaacacgt tgcgctcgcg
    26701 agcgatgata tccaggctgt catctgtgga cgggttagtg ggcaatgagc attgaggtct
    26761 gagttgcaac tagcaagtcc aacgcggcgc gcatatgagg actggcagct gcatgtggct
    26821 gcatattgga tttggtgttg ctggcggttg catcacacgc ggcgttggcg atgacgacga
    26881 atagcataac atacgccata caacatacat gatagatctg cagcgcccac gttcaaatct
    26941 cgaatacggg ttcaaagcct ccagtcgttc ccactcgctc gcatcacagt tgccgcttga
    27001 agcgaggtag attcccaaaa ccacacgcat atcctagatg catgaagggc tctcagtgcc
    27061 tctctgggag ctgtgataca tcgacgcacc aggacaacgc ttagggaaag cagatacaaa
    27121 gctatgagtg aaattgttta caattgtttg agaacaaaac ttatggttgt agaagtgcgt
    27181 gaccgtgtac gaaaaagaaa catgctactc tggaccttac gatccgaaag aatgactcgt
    27241 catttctttc agaccatgtc ttggagctca cattgtgaca tcgtcaatac atacaggtag
    27301 ctacataggt acattggatg tatgtattca cacgcggcaa ggcgttgctc cgcagaggca
    27361 ccgctttccg taacagattc cgtgcaccag gcacgcgccg cggaccggtc cctgcttggt
    27421 gacgcgaaaa ggcaagcttc ctctcttgat tactgtcttg tcctattctt cgctgtatga
    27481 aaaacttcat tcacgaagtt atgatggaaa atgccacgat ccacatatga acacaaaggc
    27541 tcaaggaaag agtgaatgcg gagcggccaa gttgctctgc agctgcagca ctggcacgaa
    27601 ggcgcactgt gcagaggcgc gccgcgcacc cccatctgac acggacacca attttgtctc
    27661 acccgccagg cttctaataa gagacagcca tgaatttatt tccgagttaa aatggccttc
    27721 ttctgcccac ttcgtcagac tgctgtaaag aaaaaaatgt tcccatcgct tttatgctcg
    27781 ttgaaccgac tggaaatgcc ttggcccttc agacctcgag gctcgacgat gtacggagta
    27841 tggcaccatg gattccattt tgtgcccaac atgccctctt gaacaatggc tcgcagggtg
    27901 gccaccggga agcctgccga atgtaacgag ccggatgcaa cacggcgagc tcctttttcc
    27961 aacgaaccgt tcaagatgcc aagcagatga ctgctcatct catctcgaag gcatggtcgt
    28021 ctcctgcatg gtccagctct cggttccacc ttatgacgat aaggtaccgt acaggcacaa
    28081 tcctacctgt aacctactca gcattcacca ctaccagaac accttctact aggtactaac
    28141 gctggttgct tcctccaatg ctgactgcag cctgatctct ggacgagcct tagctattcg
    28201 tgaatcgtgg agactggagt tcatggatac aaggcagttg ctcaggggat ggctgcgaac
    28261 caaccagccg acgactgaca tggtcagctg gggacgacct caactatcag atgacaagcc
    28321 gctcagcgct tctttcgatc aggtgctcaa tccccgactt tcacgataat tgagacggca
    28381 cagcgtctat ctccatcgta tttcctacat caccttcgga ttcgactgat acccaacaac
    28441 aggatgtcag actagcccga attcgagaga atggctcgtt cgtctttgcc tctcactcca
    28501 tgaaaacgac atgtcggact atgatgcatc atgctacggg aacaattagc ccgaccccca
    28561 cttgtcgaga ctctaccgtc gtgggtttct cctttccctt tgtgtcttct tgtttagacg
    28621 ggtattatca tttatgcctt ctatgcaaga acactgagga aaaccgcata tgcatgtatc
    28681 ccaatccaac acgaggcata ttggcatatt cccgggccgg atctagtacg cgaatcttgc
    28741 ggtcccgcaa agcgagcccc cgttgatgac ttcggcattc aaaaatgtcc gattgaggca
    28801 gctccagcga tgtgtgcttg gttcatcttt tttttctccc gccatgtgag catggtgatc
    28861 gtggctttga tcgcaagttt cgcttcgcgc accggccgtc agacagccat cgatatgata
    28921 tatcatgtac gcgtcagagt gaatggcact ggagactcga gagccctgcg tacggaccgg
    28981 gtgatatttt ctgcctgaag gatcaaccag agttctcgcc gtatcaggat gctttgcatg
    29041 ctttgcagac gcagctaaat aagcataggc gaggcacgcc ccgtccttga gcaatgaggc
    29101 ttgcgatgcc cgttccctcg tcagcgacgt caatgctaca accacggggt tgaatggaaa
    29161 gctcccgagt ccccgcagag ggtggtcccg aaaatatgcg aggcgagatt ctgcagcttg
    29221 acttgtcgtc cgacggacgc gctgagcacc tgtagcctgt agcctgtagg ctgtctgcga
    29281 aagaggcgag atcatgtacg gcgaatggcc aacgcaaagc atgcttcaat agcacacatc
    29341 atatatgcgt atctaggccc gtctgttgat ctagcgtcca atcacacaca gcattcactc
    29401 ttgagctacg aacagcaggg acctctcatc gaatcggaaa aaagaactcc tgctgcggtg
    29461 cggtgcgcat tattgcatca ttgcacaggg gtagcggctt ccatttggta atgaatgagt
    29521 taggtagcat gtatctatcg ttgtttgaac tttattgatt ctcagacaaa ttccgtagtc
    29581 gtgtctgcac tgtatacata ataccattac cagcaatacc aggactctag ccacccattg
    29641 gactgattgc tctacaccat tgctatcttt cgtcgttatc atgtagaagc tgacaggtag
    29701 agagggaaat ggggtttggg gggtgtgtat gagagggcga aaggaaaaca tcaagcaagg
    29761 aaatgaaaaa aaagaaccaa attagaagag agcaacaaac tgaggctgca gctctcgccg
    29821 ctcacgcatt cagatccatc gaaagaatat tgtcgcaacg atcggccttc ccatgccaga
    29881 tgatcacttt tgtcccccgg cctgaatctc acactttgga gcatggatac gggagatcgg
    29941 actgagattg tgcacgtcat cttgatgatg cattcgtggc caatctttgc cctggatctt
    30001 tatcaggcgc ctcgtgcttc atctcgccaa ggcggacact tcgccaatgc aacaacactg
    30061 cgtgttccac agagatgctg cttcgttcac gagctgcatg cacagcccgt cgggtagcgt
    30121 gtcagccgaa tagccaccac gcggagactc cgaggcaatg caacgtcctg ggcaggctgg
    30181 gctactcgtg tgttctggtg tgccatcctg atgaaaagag cacaaagggt cgtaggttcc
    30241 aacatgagtg aagatcgtgc gtggccatcg attgaatcaa ttggtgcatc atgattcatc
    30301 agacatgtct ttctcactgg gtgttcacta ttcagtgttg agagaaggaa gctgtggggt
    30361 acaagcgttg cgggcgccgg cacagacgag agtgttcagg gcaaaatcga cggtgactcc
    30421 acgagacatc agccgacatg agccccgagg gacagacatc cagcaacctg gttaacatgt
    30481 aggtacagtg gcctgtaggc agtacggagt aaaattaggc acaacgggtt gttgttttgt
    30541 tcctggtttc tttttcctat ttttcctttt tttcttggcg aaaatgcgcc ggtaaattgc
    30601 gaggaaaatc ccatactctg tactccgtac aattgagaaa atccagtctc gtcaatcctg
    30661 actctggatt gtctcggtag gtaggtattc tcatgtctca gccaagcgtc tcaggcaaga
    30721 acaatggccc cctgtggcta tcggcacatt gcaaggcctc gtactccgta tgtaagacgg
    30781 atgctcactg ctcagagcct cagcatcccg gcatcatgct agcgtcacgc aacatccatc
    30841 aaggtcatgc tcaccttgct caattgtgcc cagagctgaa ctttcgcgaa tgactacgaa
    30901 agagatagct tggcgaacag agagttcatg agccaatccc gacaatgtag atttatgaag
    30961 gtgaacgggc cagcaaaggc gtcttgccga agatagcaac caatacggtt tgcaggtacc
    31021 gtcggcccgt tttttagtcg cgggggtcgg aaatagcatt tctcgtgacg cggtaatccc
    31081 gtccatgtgc ttcttcaccc atacataggt atcttcctca ttcaatgctt aggaaggagc
    31141 acgggcataa gattgaagct gcgtcaggtg gcaatcaaga aaggttgtaa atttactcta
    31201 tactcagata ctgctatgct gtgaccgacg gttcaaactt taattccgca gtaaagcaag
    31261 ccaaagatgg gtaggtaggt agtaggtacc ctgttccagt accttatcta ttgatatgta
    31321 tcgggtttct tcaactgcta gatgcgcaat cctttgcttc tgagaccaat catggaatct
    31381 tcaacagcgc ttcacagctc tgcctgtaga tctaccagta ctcaagttta gcaccctatg
    31441 ttggcgattt acagatgcca ttgagtagaa caggagttca gagtggcctc cactacctcc
    31501 attcgaagag ttgacacttg atcatgtttc tttgcatatc gagtattgcg tcttcgccag
    31561 acgggtggca tgatctcccg ccagtggaat gggctcgaat tcgtctgtaa cagggctctg
    31621 aggtttcagt tcgtacggag ctcctacaac aatcttattg ccagtcgacg aaaatggcaa
    31681 aatagatgaa gacgatgccc ttgacccgag tggttccggt tcgtggcgtt cccgagacaa
    31741 ccttgagcga ccggagcgaa aggatgcgat ggacacgacg ctgcgaatac ttcggaggag
    31801 agcatctggt gcgactgacg caaacaccat ccagatggag ggcagattga cagcgacaag
    31861 cccgacgccc atttccagaa tgatgtagaa gacgactctg gacaagtact ctgtttcgag
    31921 ggggtttgtg agtcaagacg ttgcacccgt gtcagagacc tgaaagatcg tttccaaaag
    31981 tttgcaactt actttcaggg tcgatcctgt gaattgctga ctggccgact gtgaggaaga
    32041 gcgattgtga tgaactgtga gtcagtggca agatacaact agaacggaac aagaccagcg
    32101 cccataccag tgactagttt tattatgacg accagtcttg cgagcgcggc gcaaacacct
    32161 ctagcatccg caatatcccg aataatcagc acctgaattc tggcaggaca agaaatggca
    32221 caacagaaat atgatgagga gtcccgagtc agtaactcac aagcaagcca gcagaaatat
    32281 tcccactatg gccacttttc tgctccgcgt tgtttgcaac tgtatcactg gatacacagg
    32341 cagcaccaag actatcagat cgagcaccaa attggaagtg gcttgcgcct gcagagttgg
    32401 gtacgacctg gtgcaatact cgagctgagt accatcccac ggcgcagaaa agtgtgtgcc
    32461 gcactgaaag gcgagaagaa actcaaatat tacaacccag caggcgatga tgacgagtaa
    32521 gacgatgatg atgatattga gaacagcttt ccggccggcg acgcaaaaga tgcgcttgta
    32581 gaaaaagagg gcacttgctt tgatgcagcc gaggcaaatg atcgagacga ggctgaggga
    32641 catctgggtc tgtacatggc gagttaagtt gacgagagcg tgttagtagt gagtcgtgac
    32701 gctggcggtg caactagcat tcgacaagta gatgatgtaa acatggagaa gtgggaagtc
    32761 tggactctga ttcaagcacg gaaatagaag agagtatcac ctttccggac cgttccaggg
    32821 ttgcttgtcg ctgttccttg gatatctcaa atgtcgagta cccgattgcc tggaggtgca
    32881 ccgctagaca catgagtttg cgatggtcag cttccagcaa ttgtatttgt ggtcaccacc
    32941 gtgaaattga agacgatgga gtagcgtatg taaataccgt agaaaacgca ggaacaggcg
    33001 ccaataaagg ttatctaccc gtcataactg gtcagctagt tcgtcttttc tcctttcttt
    33061 cttctcttca atttcctgat ttcgctctca aagactcaaa cgcggaaaca ggagcatagg
    33121 ccttcaactc accaaagcag gcagcataag ccaatcgtcg gccaacaggc ttgctttctg
    33181 atgacgtctc gcataaaagc gcagtgcaac ggccacgatc acgaggccca gcggcacggc
    33241 gctcacggcc acgagggact ctgccgtcac cgtgtgatcc ggcat
//
