LOCUS       BGC0002604             17897 bp    DNA     linear   PLN 04-DEC-2018
DEFINITION  Aspergillus felis 0260 DNA, sartorypyrone A biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0002604
VERSION     BGC0002604
KEYWORDS    .
SOURCE      Aspergillus felis
  ORGANISM  Aspergillus felis
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:04:35
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1134)
                     /gene="sre1"
     CDS             complement(join(1..601,654..948,1002..1134))
                     /codon_start=1
                     /gene="sre1"
                     /product="prenyltransferase Sre1"
                     /protein_id="BBG67003.1"
                     /transl_table=11
                     /translation="MLKMYRVMETEPSPQRRSVLQLAKDLVILSRFHKYNPWLAVFSGV
                     WATLLAGASEITVNPTSISANHILQQALLCLFCGYIYCGAGMVWNDWVDRNIDKNVART
                     KNRPLAAGRVTATEGFIWMLVQFAASLWLMDIMLEGHDVAAAMIPVTIATILYPYGKRQ
                     FFRRLYIYPQYFLGFTLAWPSAIGWMAIKGREIPFMQSISESLPLAITVFIWTLYLNTA
                     YSYQDIVDDSKMNVNSAYVAAGSRIHLFLIILAGLVLGSVYLQLRAQNSGWLWASWMCV
                     WTLSFLHQLLRFDAKKPESGGPLHKENFALGLWTIVACVVELGLTSGKIEQFLSSRAFR
                     LQ"
     misc_feature    1..17897
                     /note="sartorypyrone A biosynthetic gene cluster"
     protocluster    1..17897
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[12313:17897]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12314..17897
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..17897
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..17897
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002604"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17897
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="terpene"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..13722
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2465:3722]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2466..3722
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     cand_cluster    1..13722
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(2466..3722)
                     /gene="sre2"
     CDS             complement(join(2466..2850,2900..3226,3280..3434,
                     3495..3722))
                     /codon_start=1
                     /gene="sre2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 255.3; E-value:
                     1.1e-77)"
                     /gene_kind="biosynthetic"
                     /product="geranylgeranyl pyrophosphate synthase Sre2"
                     /protein_id="BBG67004.1"
                     /sec_met_domain="fung_ggpps (E-value: 1.5e-150, bitscore:
                     488.2, seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="fung_ggpps2 (E-value: 3.1e-106, bitscore:
                     342.7, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSIPVTSLYELDRQQPFQDPSKSLWTHLNLFMPQEAQSQPVAGT
                     LTETETTSSSSHCASHGASDLKQQRKLTQEKIIWAPLDYLCSFPGKDIRGKLISAFNQW
                     LQIPEDKLDVIKRVVGLLHSASLLIDDIQDSSKLRRGFPVAHSIFGIAQTINSANFAYF
                     WAQQELQKLGKPEALIVFTEELLRLHRGQGMDLYWRDALICPTEEEYLEMVANKTGGLF
                     RLAIKLMQMESQNTKDCVPLVDLLGIIFQIRDDYQNLQSDLYAKNKGFGEDITEGKFSY
                     PIIHSIRSDPSNFQLMNILKQKTDDEDVKRYAVRIIESTGSFNYCRKKVASLTTEAREM
                     LKDFGDLGNTDGLKGILDFLELKE"
     gene            order(4585..5102,5187..5388)
                     /gene="sre3"
     CDS             join(4585..5102,5187..5388)
                     /codon_start=1
                     /gene="sre3"
                     /product="terpene cyclase Sre3"
                     /protein_id="BBG67005.1"
                     /transl_table=11
                     /translation="MDAFDLSSAPAEFRAIKPICDMLVIFTGATWVINYIVTVRQIFRD
                     RVCVMPLVCLCCNVAWEITVVLIHRPPYFLLDVFFAMWLSVNMVIVYGSIKVSMEKQLP
                     SPLMHKHLPLIIALTILGFILGYHALAKMLGPTKAVWWGGMLSQVVMSADCLGQILHRG
                     STHGASWAMWTSRVLGSYSAIAGVWVKSWFWPQQWDWFDNALTRWITGISLIMDIMYGC
                     IFWFIWQTEKGAKVQKA"
     gene            order(6407..6705,6760..7034,7103..7473,7533..8018)
                     /gene="sre4"
     CDS             join(6407..6705,6760..7034,7103..7473,7533..8018)
                     /codon_start=1
                     /gene="sre4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 264.8; E-value: 2.3e-80)"
                     /gene_kind="biosynthetic-additional"
                     /product="flavin-dependent monooxygenase Sre4"
                     /protein_id="BBG67006.1"
                     /sec_met_domain="DAO (E-value: 1e-09, bitscore: 27.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTTKSPFKVIIVGGSIAGLTLAHCLSKAGIDYIVLEKRRQIAPQ
                     EGASIGIFPHGGQILQQLGIFYLVEEQIEPLHTAHQCFPDGFMHTTKAPRIIHERFGLP
                     LAFLERRRMLRVLYGTLPDPSRVLVDKAAISVEREDSDLMSVTTHDGCVYHGNLIVGAD
                     GVHSRVRAEMWRLANSQSPGVFPEHEMSSMTVEFACVFGISSSVPKLKAGEQVASFNNG
                     RSFLTFPGKNGRIFWFLLLKLDRKYSYSNAPRFSSADAEKISERFADDHIWDGVYFRDL
                     WKNREVFSFVNLEENVFRKWHWERIVCIGDSMHKMAPNTGQGANSAIEDAAALVNCLHR
                     AFRATPDSSTLSSAEIDGLLAEFNRTRFRRVREIYQGARLVVRLQARQNLFLRLLGRYY
                     LPYAGDVPADAASKIIAGAEHLDFLPLATRSGAGWYRFKPGQSGTALIPCLYPVLALTL
                     CVLAWIGNDFVRNRVVFA"
     gene            order(10609..11384,11441..11969)
                     /gene="sre5"
     CDS             join(10609..11384,11441..11969)
                     /codon_start=1
                     /gene="sre5"
                     /product="acetyltransferase Sre5"
                     /protein_id="BBG67007.1"
                     /transl_table=11
                     /translation="MSASERRVFETLLYAIPFLLAQNLVPAIVVLRTKKNSVLRYLWIV
                     WSVYVFSRWLQIPISHGESATYTTKVGVQLFMVIIQGFNLVLINPLDNNELLQTKTIDP
                     RDHFLCKTYKVARLFIYLRGVRTPWQAKKIPSQPAFLARQPKAPISRSAFLMRQSAILA
                     WLYLFLNCTTYLAAGDSSQLSKPVYGLGYLRVSKEEWRTRIITSLMFWFAFLRAAVDID
                     YRTASTLTVGIGLDAPEDWPPLFGHAKEAYTLRKFWGTYWHQMFRWPLTAISNYLARGL
                     LALPRPSLLERYTNIFFVFLLSGVMHVMSDLFMGIPLSQSTSLFFFCSMTSGIMIEDAV
                     QAAWSRLADSHHPGRASTVRSDGCAVPCWQKLVGFIWVCSWLSLLTPIWLYPMQTSRGK
                     GLFLVNIPELVGTPTAIAMTVGGGLAVKYIFRGEL"
     gene            complement(12314..17897)
                     /gene="sre6"
     CDS             complement(join(12314..17206,17268..17897))
                     /NRPS_PKS="Domain: SAT (88-255). E-value: 7.9e-11. Score:
                     33.8. Matches aSDomain: nrpspksdomains_sre6_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (393-805). E-value:
                     1.7e-145. Score: 477.0. Matches aSDomain:
                     nrpspksdomains_sre6_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (906-1176). E-value: 4.1e-50.
                     Score: 162.7. Matches aSDomain:
                     nrpspksdomains_sre6_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1303-1396). E-value: 3.2e-08.
                     Score: 25.9. Matches aSDomain:
                     nrpspksdomains_sre6_PKS_DH.1"
                     /NRPS_PKS="Domain: ACP (1634-1673). E-value: 4.2e-07.
                     Score: 22.1. Matches aSDomain: nrpspksdomains_sre6_ACP.1"
                     /NRPS_PKS="Domain: PP-binding (1744-1797). E-value: 1e-08.
                     Score: 27.5. Matches aSDomain:
                     nrpspksdomains_sre6_PP-binding.1"
                     /codon_start=1
                     /gene="sre6"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 241.2; E-value:
                     3.3e-73)"
                     /gene_kind="biosynthetic"
                     /product="polyketide synthase Sre6"
                     /protein_id="BBG67008.1"
                     /sec_met_domain="itr_KS (E-value: 1.4e-149, bitscore:
                     487.1, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.4e-51, bitscore: 162.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-09, bitscore:
                     27.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALALPSIIVCGSQTPPPSRECLQRIRSNLKNPKLKELAKAVDDL
                     PQFWSRLVEIKPILSQVNDEPLQKLKDWARDECLLEIPEDLPNILLAPLTVIIHLVQYL
                     RFAHSLNADDFQEDRHRRILQSTCKGGFQGLCTGFLSAAALACSRTERDVSCNATVALR
                     LATCVGGYVDLDRLTYDSTDVYVCMIIHWEDNCGKDRVTEVLKGYPEVYTSVELDDRSI
                     TVTAKQSQVSSLRADLAARNAKVTNIPIHGRYHSITHAEILQDLVEICNNDESLRFPII
                     NTPFVPLRNNTTGDLITSAEKLHELTLKCVLTEPANWYSTMTETISSLKSQPEKNQRPL
                     ILELGLVSCLPRSLTASANLQVFSPPLTSTVSPKDQKSSTNDEHRYDYPEHSTAVIGAA
                     CKFTGAETMQQFWELIRTGGTTIGDLPEGRIAVDKSLRKAPREKSLRGNFLSDAGHFDH
                     GLFGVSPREATYMDPQQRIALRVAYQAVESSEYFGSHIKDKNIGCYVGVGGSDYDHNVC
                     SHAPTAFSFTGTARAFVSGRISHYFGWTGPSMTIDTACSSSAVAIHQACKDIRMGECRM
                     ALAGGVNIISCPNMQENLAAARFLSPTGPCRPFDASADGYCRGEGCGFVMLKKLSCAVA
                     DNDDILGVIVGSAANHCDGNDAITVPTSHSQVNLYRKALSLAAMEPKDITYVEAHGTGT
                     PRGDPVECRSIRQVFGGSRPTLHFGSVKANIGHTEAASGIAGLLKVLLMIRNQRIPPQA
                     NFTALNASIPPLEPDNLSVPINELEWKAIFRAACINNYGAAGNNAAVIVCEPPRPDSSA
                     GNNDRLSAYPFLITGQSERSLKMYCTALSHWLDNARAPLSDIAFNVARRQNRTLRHRIA
                     FAASSLSELRSILGQKARPHEQLLSPSPKPKPVVLVFAGQTGNIVYLPKAAYEGSRLLR
                     SHIDECDGILRRMGHRGLIPFLFDQQPIEDVVLLHCLFFSLQYACAAAWLGAGLPVHRV
                     IGHSIGQFTAMCISGITTLADTLKLVAGRARLIQQKWGKERGCMLAVEVDRQGALEVAR
                     SVPDHKIEIACFNGARNHVLVGTEVAIHTLEGKTSCKTRRLKTTHGFHFEMVDCLLDDY
                     MALARNISYATPNIPIETCSMGGRWKEFTPELVVRHSREAVYFFDAVSRVNEELGPCTW
                     VEGGAGSRGIALVKCALGIESSSGHSFHRLQLDSSEPLASLTETTMQMWNEGLDVQFWL
                     YHDAEKSTFASCDVPGYQFDETAFWLLYSDKAGQSDSEQEMIISDEHKPLVYLLKDEGF
                     REEPRKLHFGVNHCHPDFSRYLNGREVLGEVLCPVSVFVELAAKAAAIPGGRECSMAFA
                     HVQVLDLEIHNPLGHARGVRVGLRLNHVGPCKWGFSIISEKNAQSICHATGTIFLKQER
                     HGKSGMGSQWSVIQRVIGYSHIQDIIDDRSAISMKGSLIYKVLEKVAEYKPCYRGIKAM
                     TIKDTAAVAQLEMPKIGRNCSEIAVCDPLVMDQVTLIAEVLALCRDDCKRDDVFICSGL
                     NELVTFKSLKSETGPWTVYTRQTLRGPRELLSDTFVFDSTSKQLIVAILGARFVRITTS
                     SLDGIVKRASLNSQTSELPVETEAVYEPATKACRPSDDSEVSDIDPILSRLLHEIAGIS
                     PGEIFPSTLLVEAGVDSLAATELENRIQEVFNLHRPISLYERQFDVGTLCREIQTQRDD
                     RLARASRTTTATRNTSSSLGRRTSSTGSLSDNAEARSISNSDAVLAQLSRMLSESLNIT
                     ENILPGTELRSLGLDSLVAVELESDLQQAFGLKVDLMQLSPELTMGGLARLILASKSQT
                     SRHMAPSMVDSGQKTEPENQTYLAG"
     aSDomain        complement(12446..12604)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_PP-binding.1"
                     /evalue="1.00E-08"
                     /label="sre6_PP-binding.1"
                     /locus_tag="sre6"
                     /protein_end="1797"
                     /protein_start="1744"
                     /score="27.5"
                     /tool="antismash"
                     /translation="LSRMLSESLNITENILPGTELRSLGLDSLVAVELESDLQQAFGLK
                     VDLMQLSP"
     aSDomain        complement(12818..12934)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_ACP.1"
                     /evalue="4.20E-07"
                     /label="sre6_ACP.1"
                     /locus_tag="sre6"
                     /protein_end="1673"
                     /protein_start="1634"
                     /score="22.1"
                     /tool="antismash"
                     /translation="AGISPGEIFPSTLLVEAGVDSLAATELENRIQEVFNLHR"
     aSModule        complement(12818..16657)
                     /complete
                     /domains="nrpspksdomains_sre6_PKS_KS.1"
                     /domains="nrpspksdomains_sre6_PKS_AT.1"
                     /domains="nrpspksdomains_sre6_PKS_DH.1"
                     /domains="nrpspksdomains_sre6_ACP.1"
                     /iterative
                     /locus_tags="sre6"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(13649..13927)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_PKS_DH.1"
                     /evalue="3.20E-08"
                     /label="sre6_PKS_DH.1"
                     /locus_tag="sre6"
                     /protein_end="1396"
                     /protein_start="1303"
                     /score="25.9"
                     /tool="antismash"
                     /translation="RYLNGREVLGEVLCPVSVFVELAAKAAAIPGGRECSMAFAHVQVL
                     DLEIHNPLGHARGVRVGLRLNHVGPCKWGFSIISEKNAQSICHATGTI"
     aSDomain        complement(14309..15118)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_PKS_AT.1"
                     /evalue="4.10E-50"
                     /label="sre6_PKS_AT.1"
                     /locus_tag="sre6"
                     /protein_end="1176"
                     /protein_start="906"
                     /score="162.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: inactive"
                     /tool="antismash"
                     /translation="VFAGQTGNIVYLPKAAYEGSRLLRSHIDECDGILRRMGHRGLIPF
                     LFDQQPIEDVVLLHCLFFSLQYACAAAWLGAGLPVHRVIGHSIGQFTAMCISGITTLAD
                     TLKLVAGRARLIQQKWGKERGCMLAVEVDRQGALEVARSVPDHKIEIACFNGARNHVLV
                     GTEVAIHTLEGKTSCKTRRLKTTHGFHFEMVDCLLDDYMALARNISYATPNIPIETCSM
                     GGRWKEFTPELVVRHSREAVYFFDAVSRVNEELGPCTWVEGGAGSRGI"
     CDS_motif       complement(14768..14872)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sre6_0005"
                     /evalue="3.20E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="sre6"
                     /protein_end="1023"
                     /protein_start="988"
                     /score="44.9"
                     /tool="antismash"
                     /translation="VIGHSIGQFTAMCISGITTLADTLKLVAGRARLIQ"
     aSDomain        complement(15422..16657)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.70E-145"
                     /label="sre6_PKS_KS.1"
                     /locus_tag="sre6"
                     /protein_end="805"
                     /protein_start="393"
                     /score="477.0"
                     /tool="antismash"
                     /translation="AVIGAACKFTGAETMQQFWELIRTGGTTIGDLPEGRIAVDKSLRK
                     APREKSLRGNFLSDAGHFDHGLFGVSPREATYMDPQQRIALRVAYQAVESSEYFGSHIK
                     DKNIGCYVGVGGSDYDHNVCSHAPTAFSFTGTARAFVSGRISHYFGWTGPSMTIDTACS
                     SSAVAIHQACKDIRMGECRMALAGGVNIISCPNMQENLAAARFLSPTGPCRPFDASADG
                     YCRGEGCGFVMLKKLSCAVADNDDILGVIVGSAANHCDGNDAITVPTSHSQVNLYRKAL
                     SLAAMEPKDITYVEAHGTGTPRGDPVECRSIRQVFGGSRPTLHFGSVKANIGHTEAASG
                     IAGLLKVLLMIRNQRIPPQANFTALNASIPPLEPDNLSVPINELEWKAIFRAACINNYG
                     AAGNNAAVIVCEP"
     CDS_motif       complement(15638..15682)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sre6_0004"
                     /evalue="5.70E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="sre6"
                     /protein_end="733"
                     /protein_start="718"
                     /score="12.3"
                     /tool="antismash"
                     /translation="GSVKANIGHTEAASG"
     CDS_motif       complement(15734..15781)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sre6_0003"
                     /evalue="8.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="sre6"
                     /protein_end="701"
                     /protein_start="685"
                     /score="11.8"
                     /tool="antismash"
                     /translation="YVEAHGTGTPRGDPVE"
     CDS_motif       complement(15974..16012)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sre6_0002"
                     /evalue="3.20E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="sre6"
                     /protein_end="621"
                     /protein_start="608"
                     /score="16.7"
                     /tool="antismash"
                     /translation="FDASADGYCRGEG"
     CDS_motif       complement(16154..16201)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sre6_0001"
                     /evalue="1.50E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="sre6"
                     /protein_end="561"
                     /protein_start="545"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSAVA"
     aSDomain        complement(join(17072..17206,17268..17633))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sre6_SAT.1"
                     /evalue="7.90E-11"
                     /label="sre6_SAT.1"
                     /locus_tag="sre6"
                     /protein_end="255"
                     /protein_start="88"
                     /score="33.8"
                     /tool="antismash"
                     /translation="ILLAPLTVIIHLVQYLRFAHSLNADDFQEDRHRRILQSTCKGGFQ
                     GLCTGFLSAAALACSRTERDVSCNATVALRLATCVGGYVDLDRLTYDSTDVYVCMIIHW
                     EDNCGKDRVTEVLKGYPEVYTSVELDDRSITVTAKQSQVSSLRADLAARNAKVTNIPIH
                     GRYH"
ORIGIN
        1 tcactggaga cggaaagccc ggctagacag gaactgctcg atcttccccg acgtgagtcc
       61 caactcaaca acacaggcaa cgatagtcca cagccccagc gcaaagttct ccttgtgaag
      121 cgggcctccg ctctctggct tcttcgcatc aaatctcagc agctgatgca aaaacgacaa
      181 agtccagaca cacatccacg aggcccacag ccagccggaa ttctgggccc gcagctgcag
      241 gtagaccgaa ccgagcacga ggcccgccag gatgatcagg aacaagtgga tgcgggaccc
      301 ggcggcgacg tacgccgaat taacgttcat ctttgagtcg tcgacgatgt cttggtagct
      361 gtacgccgtg ttgaggtaca aggtccagat gaagacggtg attgccagcg ggagggactc
      421 gctgatgctt tgcatgaatg ggatctcgcg gcctttgatt gccatccaac cgattgcgct
      481 gggccacgcc agtgtaaagc cgaggaagta ctggggatag atgtatagtc gtcggaagaa
      541 ttgacgcttt ccgtagggat agaggattgt ggcgatggtg actgggatca tagcagccgc
      601 gctgtttttg atcagctatc cgcgttcctg agactcttgt gagaggttca tacacgtcgt
      661 gaccttccag cataatatcc atcagccaca acgaggcagc aaactggacc aacatccaga
      721 tgaagccctc ggttgcagtc actctccctg ctgccagggg tcgattcttg gtacgcgcta
      781 cgtttttatc gatgttgcgg tcgacccagt cattccagac catgcctgca ccgcagtaga
      841 tgtagccgca gaataagcat agaagagcct gttgtaagat gtggttggcc gagatcgagg
      901 tcggattaac ggttatttca ctagcaccgg caagcaacgt tgcccaaact gagatggccc
      961 gaggtcaatg gacgaatatt gtatataagg aagggacaca cctcctgaga atacagcaag
     1021 ccatgggttg tacttgtgaa atctggatag gataaccagg tccttcgcga gctgcaggac
     1081 ggatcgccgc tgaggagatg gttcagtttc catgactctg tacattttga gcatttgtct
     1141 atccggcagc gagttgagaa tggcgaagca gaaagtcaac taacggttga tatatcaatg
     1201 accatgatgt tcaaggaggc aaatatacat cgcaaatatt acctcaatac cccggcctta
     1261 ccttcttcgg agttgacaga cacggaaaag ccccgacagc gagttaaaac caccgacagc
     1321 tacatactag ggctgactga ttgacatgca cggtatcaag ggtcagccca cgtcactgct
     1381 tcacttgttg cctgactcgg cattctctca agcagcccag ctgacaagcc tcgaaactgc
     1441 ccaattgagc atatcagcaa ccctgcaact tcattatctt aaccggggtc ttggtcagaa
     1501 cgctaacagg agttctttag ctgtcgaata agccgaggac cgtgaataag tgcctggata
     1561 ggcgtcgact gcaatagctt atcataccaa gcggctaatg tacctcattc acaatcaaga
     1621 cacggattcg gtctcggaag acatctgttg aaagtgacct gattggcacg gtgtttacgg
     1681 acttgccttg catgaatttg gcccggagcc agggtgtccc ttcttggctg acaatcagct
     1741 tacggaccaa gacaagccga cactattggc tctgcgacct atgatagtga ttagtggcat
     1801 aatagtctga actattgaat tatggcctgg aacgagatga atcttctgaa catgtagccg
     1861 cttataacaa tctggatctt gatctatggc tgggaatgca ttactcttgc acctgattgg
     1921 gcattggggg taaagggtaa ggtagtattg ggttgagtta ctgctgcccg aattccgatg
     1981 gattcaagtt gactcagcac tgccaccatt ggcagatatt tgttatcgtt cgttttatct
     2041 ctatggattt ggttgattcg gatatctgct tatttgccat gtccagtgta tcgatgggca
     2101 tagtcaccct ttgttcagca ggtagttaat ggcttgaatg aggtatgccc tgattatata
     2161 cttacttatt ttagataatg taatatgttc tcttgactgt ttcattcctt tggattttgg
     2221 cataaaacgt gaacccactg tatgtagaaa tacgtacagt attaagagca tgattctatc
     2281 tgtttctgaa gagggcctaa attacgcata aactcctgtc acctgtgtag gcgcatactg
     2341 ctgattatca accctgtaga caagacctga acataagggg caccagaata aaatcaaatt
     2401 gcaagtcagt tataaagcaa cagccatttt gcccatgata tgcacacagg tgataaccag
     2461 cgcagctact ccttcagctc cagaaagtcc aatataccct tcaacccgtc tgtgttgcct
     2521 agatcaccaa aatctttcag catttctctc gcctctgtcg taagactcgc caccttcttg
     2581 cggcagtaat tgaagcttcc agtagactcg atgatgcgaa cagcgtaccg cttgacatct
     2641 tcgtcgtcag tcttttgctt cagaatattc atcaactgga aattgctcgg atcactgcga
     2701 atgctgtgga taatggggta ggagaatttg ccctcggtga tgtcttcacc gaaccctttg
     2761 ttcttagcat acaggtcgct ctgaaggttc tggtagtcat cgcgaatttg gaaaatgatt
     2821 ccgaggaggt cgacgagcgg cacgcaatcc ctgtatccct attaatcacc atacatgcag
     2881 tgtaaagcga gtagctcact ttgtattctg gctttccatc tgcatcagct tgatcgcaag
     2941 ccggaacagc ccgccggtct tgttggcaac catttcaaga tactcctctt ccgtggggca
     3001 gatcaaggca tctcgccagt agagatccat cccctgcccg cgatgaagcc tcaacagctc
     3061 ttctgtgaag actatcagag cctcaggctt gcctagcttt tgtagctcct gttgagccca
     3121 gaagtaggcg aaattggccg agttgatagt ctgcgcgata ccgaaaatgc tatgcgcgac
     3181 gggaaatcct cgtctgagtt tcgacgagtc ttgtatatcg tcaattctgt aaattgtcag
     3241 ctttatcttc gcctggcaag catgcagaga acagcgtaca gcaacgaggc cgaatgcagc
     3301 aggccgacca cccgcttgat gacgtccagt ttgtcctctg ggatttggag ccattggttg
     3361 aaggccgaaa tcaacttgcc tctgatgtct ttgcctggga agctgcaaag gtaatcaaga
     3421 ggagcccaga ttatctggtg ggagaagctt gttagagtac agaacgttac caaagggcaa
     3481 ggtttaccgc gtaccttttc ttgagtgagc tttctctgtt gcttgaggtc agatgcaccg
     3541 tgagaggcgc aatgggaact agagcttgtt gtttctgtct cggtcagagt gccagctact
     3601 ggctgagatt gagcttcttg aggcatgaac aagtttaagt gagtccatag cgactttgac
     3661 gggtcttgga agggctgctg gcgatcgagc tcatagaggg acgtaactgg aattgatacc
     3721 atattgcagc agatggggag gtagatctaa agactagtag atactagaga gatatgaatt
     3781 ggtcttttgc aggtgcactt agaaatgtga aatatacaga accgtacaac ccaggcacag
     3841 ttgaagcaaa tcagaacaag aagataagcc gcaatggttc aagcttgata ctagtttgga
     3901 gtcactttat ccatttgaaa tgtaacctta cgacgcccgc cgaagatcaa agaataccat
     3961 gaccatgcca gtgggtgtgg tttcggagta tactgctaac gacgtggaaa gaaaggaaca
     4021 agaccagccc ggaggagatt ctcactcagg agctgcatcc ctgctccgag ggtgtcagct
     4081 tggcatatca cttgttccac attgtcaact gagccaaagg tcatggcgtc tactagccgg
     4141 actaagagtt tgtattcctg accggccacc gacaaggaac agccatctca taatcctcga
     4201 tacacgatcc tcatcctcat ccgattcctt cctgaagccg acatgcaact aggtccgacc
     4261 agatggatgc acgatgtacg gagtactgtg tcctaccagg attatccacc gaattgcaat
     4321 tgggcggata atgcctcttg atgtattgtt gtatccctgc tgttttgacc ctactgctat
     4381 catccctact agctagagat ggttgtctag acacctctat ggctgaggga ttcgatatat
     4441 aacacgtatc atcaagacat ccctagttga cagggagtag gaaccattag aaagcgacaa
     4501 ttgttgggtc cagatattct ccgaactgta ccctgattaa tctcagtcag aatcacattg
     4561 gcaacatccc tactgcccac caacatggac gcatttgacc tttcctcagc tccggccgaa
     4621 ttccgggcca ttaagcctat ctgcgacatg ctggtcatct tcaccggagc gacctgggtg
     4681 atcaactaca tcgtcacggt acggcagatc ttcagggaca gggtgtgcgt gatgcctctg
     4741 gtctgtctct gctgtaatgt cgcctgggag atcacggtcg ttcttataca ccggccccct
     4801 tacttcctcc tcgatgtctt ttttgccatg tggctgtcgg tcaatatggt catcgtgtac
     4861 ggctcgatca aagtatccat ggaaaagcag cttccctcgc cgctgatgca caagcatcta
     4921 cccctgatca tcgccttgac tatcttggga ttcatcttgg gttaccatgc gctcgcgaaa
     4981 atgttggggc ctaccaaggc cgtctggtgg ggaggaatgc tttcccaggt ggttatgagc
     5041 gctgactgtt tgggtcaaat tttgcaccgg ggaagcacgc acggggcgtc gtgggcgatg
     5101 tggtaggtgt ctttgctatg gatgaatttt tcctcttgaa tagaatatgc tggaagctga
     5161 caattggtct ctatcggatt gtccaggacc tcccgcgttc tcggttccta ttcggcaatc
     5221 gccggtgtat gggtgaagtc ttggttttgg ccacaacagt gggactggtt tgataatgca
     5281 ctgactcggt ggattacggg catctcattg attatggata tcatgtatgg ctgtatcttc
     5341 tggtttattt ggcagaccga aaaaggagcc aaagtacaga aggcgtgagt cgagttgcat
     5401 gttctatgga cgcagactca ggaattattg gcgggacata aagcatattg cacttccctg
     5461 cacaatttac gagtatcttt atgatagtta cctcagaatg cctgctctgc atacaaggaa
     5521 tccatgttca aatcaacaga gtacttccct gaccgtgctt tcccctacgt ttgagtcttt
     5581 tccaaatttt ttccttgctg aatttcaaat cgacttcatg gcaaattcag ctggttctga
     5641 tcccaatagc tttccgagcg ccgtcataat gtacattggt acttcgagac ctccaattgc
     5701 ccggaaaggc gagtttgctg ataacgaagt atcttttcac agacactgac aacaacatgc
     5761 agatgactgc agattgtcca ttatccatgg aattgctacc aagtctcaca ttttatgggc
     5821 tttataagac actaagcatt cccctaagcc gattggacag aatatcaata tggaagaata
     5881 cagaagatga aatatatcat ttctccttgt cgacaatcca gcggatcgat cagggcctct
     5941 gtgagcaaac aggcgttcct tacgcaacat aaggtacgga gtagtattga gttgcttcct
     6001 atgtatgcac atgtttatgt acataattcc atagtttagc acgtccctat atcccctcgg
     6061 aggtctcagg agggcaggct tcgcctgcct tccgctggac attaatgaat aatacgacaa
     6121 caacgccaac gtagggtagt atttccaatt ctgacccgga tcggagaact gctcgtcggc
     6181 agacacaagc cggtatctgc ataacaattg aaacagggat ttcctcatat gtcaggactg
     6241 ctcttcagag tagtctccat atgatagccc acattcccta cctatatttg tgtccattct
     6301 ctgtagcggt ccatcatcgc tgaccaagag acgtttattg tcctcttccc ctgctctcct
     6361 ggtttacctg gacgcggata gtgaggctta ctcgagtacg ttgcctatga tgacgaccaa
     6421 gtcccccttc aaagtcataa ttgtgggcgg atcgattgct ggtctcaccc tcgcccactg
     6481 cctcagcaaa gcaggtatcg actacatcgt tctcgaaaag cggaggcaga ttgcgccgca
     6541 ggaaggcgcg tctatcggta tttttcctca tgggggccag attttgcagc agttggggat
     6601 attctacttg gttgaggagc agattgaacc attgcacacg gcgcatcagt gcttccctga
     6661 tggctttatg cataccacta aggccccacg aattattcat gagcggtact gtattatcta
     6721 catgtgatgg accgtattca cagctaatct ggctgatagg tttggtctgc ctctcgcctt
     6781 tctggagcga agacgaatgc tcagagtgct ttatggcaca ctcccggatc cgtcccgagt
     6841 tctggtggac aaggctgcca tttccgtgga gagggaggac tcagacctga tgagtgtcac
     6901 gacccacgat ggatgtgtat atcatggcaa tctgattgtc ggtgctgatg gtgtgcacag
     6961 tcgagtgcgc gccgaaatgt ggcggctggc caattcgcaa agtccgggtg tattccctga
     7021 gcatgaaatg agctgtgagt tgagtactgc cacattcaag gaagatgcga tcgaataaag
     7081 ctgattacat ttaaatttcc agcgatgaca gtcgagtttg cctgcgtctt cgggatctcg
     7141 tcttccgtcc ccaagctgaa agcaggcgag caagtggcca gcttcaacaa tggtagatcc
     7201 ttcctcacgt ttcccgggaa aaatggtaga atcttttggt tcctcctgct gaagctcgac
     7261 cgcaaatact cgtactccaa tgctccgcgt ttctcctccg cagacgccga gaagatatct
     7321 gagcggtttg ccgatgacca catctgggac ggagtgtact tccgagacct atggaagaat
     7381 agagaggtat tctccttcgt gaaccttgag gaaaacgtgt ttcgaaaatg gcattgggaa
     7441 cgaattgttt gcattggtga cagcatgcac aaagtaggtt tctgtcttcc gggatatgaa
     7501 cccgaaattt tgatctgaca tgcctcgaac agatggcccc aaatacaggc caaggggcca
     7561 actccgctat cgaagacgcc gctgcccttg tgaattgcct ccatcgggct tttagagcaa
     7621 cacctgatag ttctacctta tcatctgctg aaatagatgg tctcctggca gaattcaatc
     7681 gaacccgatt tcgccgtgta cgtgaaatct accaaggagc caggctggtt gttcgattgc
     7741 aggcaaggca gaacctgttc ctcaggttgc tcggacgtta ctacctgccc tacgccggcg
     7801 atgtccctgc ggacgcagcg tccaagataa tcgctggagc tgaacacctg gactttttac
     7861 cgcttgctac ccgctcaggg gccggatggt atcggttcaa gccaggtcag agtggaactg
     7921 ccttgatacc gtgcttgtat ccggttttgg cccttacgtt gtgtgtcctt gcttggatcg
     7981 ggaatgattt cgtccgaaat agagttgtgt ttgcttaaga cctgttgtat atggatagga
     8041 ctctagaatc tgatgcacta ctatgaagtc aattacctat ctcgcatgaa tgagttccgg
     8101 cggccaatat agactcggaa acattgtcag ccgtgccaaa tacccttctt gtaaaagcaa
     8161 gtgatacttc tttcggcaaa agtacagtac agcttctcac attgcgatta tgcctcttta
     8221 ataggtagct ggtctgtgca tggagcgtcc tgttgaaacg ccattctgct ggctatcctg
     8281 gagacgacac ccgccccaac tccgataatg cagatcggtt tggaagagat atgaaattcg
     8341 gctaaccatc actcaaagca atctcggaag atcaacgcca gtctctcagc tgtgccatag
     8401 agacaatggt ctgcgtaatt tccaatcggg ccattggctt cttaaatggc aaatgttctg
     8461 gacctgctcc gttcagttac tgggggtgat ttcaattcgg accaattcaa gaaagccatg
     8521 cccggagggg gaggctgcgt acggtgttgt atacgtggtc acgcacagca actcatttgc
     8581 ttttttgggt agccaggaga gggtttgtca atatctgaat gcataataat ctgttggggc
     8641 ttctgccgag tcggattatt tgattgtctg gcctcgaaga aggtctgcag gcacattgtc
     8701 aactggactg ttgtcatcag cagtgattat gtgtgattct atcttatggt ccgcgagtat
     8761 gtctgatgca tttacagagc aaggaggagt gtatttatcc tgcaagggag atgtagcctt
     8821 tacaaacata tcgtcttttc agctttaatc tagtggttac atggtctgca atagggaaag
     8881 acaacatcac ttcgggatat ctgaggtgcg tcgggatctt cggcaatatt gaaccccgta
     8941 tgctgaggaa caatgtcgta tcatagtcta gactattgga aaccagcccg gccgctgtgt
     9001 tttgacgtgc gtacactact ccaagtgcaa ttgaaccaac acattcacgg tgaggtggat
     9061 atgcggtaag gaagagcgtc atagtgactt gatacgccac ggggaaacac aatcagaaga
     9121 gaatgatttg ctcagacaag gaacctatac ttggtgccta acatgttcat cgtccaatgt
     9181 ttgccagcag gaagatgagc accgatcctt cccatcagag agctaagata tctatcttct
     9241 agcaacccct acaggagacg gatgcaaaaa cgtatcgaga acgatccgat gaaagtatgt
     9301 aaaatcgatt acactggcct aaacacaggt agagcatcct cacatagaaa cctcctctgg
     9361 ggatatcggg ttcacttggc agacgtgttt tccaggcagc gcgtaccata cagagacccg
     9421 tcctgaggga cgcaaaataa tctccatatt cacggcgagc taaatcatac ggtaagctat
     9481 gttatgccaa tctaaacttg ccagattcgc gagaactaaa tagggaagaa cacggatcta
     9541 cctaggatat ctgtccagag atcaacgagg accgtttgta ttttggacga aacgcgctgg
     9601 actgcctatt cggaaccgat tgtttcgttc ggctatgacc atcgaacttg gtgacgggtg
     9661 tacttctaac caagacacta gtccattttt ctccttgccg cttgatccaa tgtatggttg
     9721 tcgaaggaat ctcgtggaag tcctcggacc aaggaagaca ataatgaaag cactcatgta
     9781 atgtccctgc cataacaagg ctgtcacagt ctttagattt tcccgcatat tcacagttag
     9841 ccgatcctgg atactcaacg acacgtggtg gatctcacct tgaagcctca cattatcagt
     9901 tcttgagtgt cggttccagc ttcgtcattg atgagctgtt tatcgatcaa ttcatggcgt
     9961 tccagaagcg ccaaaagcag tttggcaaga gaatagacgg ctacagacat acacaacacg
    10021 cgagtggtga ggatgtcgtg gatcaaagca accagcatta tgtagtgatc cttgattaaa
    10081 tcaatcaacc ttgagtgggt gaaactgcag ttgcggccag cgcactgtat tataagttgc
    10141 tgccgtgtca aatgagttga ctgatttctg cctatcacat ataaatcaac atgttatccg
    10201 gctgcatgga gcttcaaatc agagatgggc cgtcctcatg cattagcctg ttgtgattct
    10261 gccgaggacg agcaccgcat gaatgaaaat attctttaca agtcggtttc ctggccctgt
    10321 ttgatattct catctccgta cgtaccattt ggctcggtca gctctggctt cccatgagcg
    10381 aactacagtt gataacgcaa gtagcaaatg ctgggccctt caagggggaa aaaagcatat
    10441 attttgaatt agataatcct tcttgagtga ggtccctcgc tattgccatc agttactaag
    10501 gcccgattga tggcacatga atctgatata cgtaccttga caacgacacg cgattttatc
    10561 attctgagag ttatcagtgt gcacaatttc tcccacctag tcaagggaat gtctgcaagc
    10621 gagcgtaggg tcttcgaaac cctgttgtat gccattcctt tccttcttgc tcagaattta
    10681 gtacctgcca tcgtggtcct gagaacgaag aagaactcag ttctcaggta cttgtggatt
    10741 gtttggtccg tctatgtttt ctctcgatgg cttcaaatcc cgatatcgca cggtgagagt
    10801 gccacataca ccaccaaggt gggagtccag ctttttatgg tgatcatcca gggcttcaat
    10861 cttgtcttga tcaacccgct ggacaacaac gagcttcttc agacaaagac cattgatcca
    10921 agagatcatt tcctgtgcaa gacgtacaaa gttgcccgtc tgtttatata tttgcggggc
    10981 gtgcggacac catggcaagc gaaaaagatc ccatctcaac cggcattcct cgcacgacag
    11041 ccaaaagccc caatctctcg cagtgcattc ttgatgagac agtctgctat cctggcgtgg
    11101 ctgtacttat tcttaaattg tacaacctat ctagctgctg gagactcatc acaactatca
    11161 aagcccgttt atggcctagg ctacctccgc gtttccaagg aggaatggcg aactcgaatc
    11221 ataacctcgc tgatgttctg gtttgccttc ttgagggcag cggtggatat tgactatcgc
    11281 actgcgtcta ctttgactgt tggaataggc ctggatgctc cagaggactg gccaccactg
    11341 tttggtcatg caaaagaggc ctacactctc cgcaagttct gggggtgagt tgtcaccata
    11401 cagctgtgag taggatctgc taacgtgcct atattttcag tacatattgg caccagatgt
    11461 tccgatggcc actcactgcg ataagcaact acctggctcg gggtctcctg gctcttccta
    11521 ggccgtcgtt gctcgaacga tacaccaaca tcttctttgt ctttctcctt tcaggcgtga
    11581 tgcatgtcat gtcggaccta tttatgggca tccctttaag ccagtcgact tctcttttct
    11641 ttttctgctc catgacgtcc ggaattatga ttgaagatgc ggttcaggca gcttggtctc
    11701 gactcgctga cagtcatcat cctggaagag cttccaccgt ccgcagtgat ggatgtgcag
    11761 tgccttgctg gcagaagctt gtgggcttca tctgggtgtg tagttggctt agtctcctga
    11821 ccccaatttg gttgtatcct atgcagacgt cgagagggaa aggcttgttt cttgtcaata
    11881 ttccagagct tgttggtaca ccgacagcta ttgcgatgac tgttggtgga ggtcttgcgg
    11941 taaaatatat ttttcgcgga gagctttaga acagtacgac aacaaattgt actcgggcaa
    12001 ctggattgcc attctcagta gtatctattt tcggaagcag tgaagtgcaa gatataaatg
    12061 acaaagtatt attaggaatg agaaagatca ttaaggaatc caagcaaata gacagaacac
    12121 aacactactc gcaaatgatt ggccgtgggg tccggagata atccggtatt agggctcaat
    12181 cttagggctt gcaccttcgc tgtcgtcttt cctctgcttc ctgcattcca acacactttc
    12241 gacaagagca aaacggaaca tccatcacaa agcactctta aatctacatt aatgtctagc
    12301 attttaaaag ctgttatcca gccagatacg tctggttctc tggttccgtc ttttgtccag
    12361 aatccaccat ggaaggtgcc atgtggcgag acgtttgaga cttagacgcc aaaataagcc
    12421 gagcgagtcc gcccatcgta agctcgggac tcagttgcat caaatccact ttcaagccaa
    12481 atgcttgttg caggtcggac tcgagctcga cggcgaccaa tgagtccaga cccagacttc
    12541 gaagctcagt tccagggagt atgttctctg tgatgttcaa gctttccgac aacatccttg
    12601 atagctgggc aagcacggca tcgctgttac ttatagatcg tgcctccgca ttgtcagaca
    12661 gtgatccagt ggatgatgta cgtcggccga gagacgatga agtattccgt gtggcagttg
    12721 tcgttcgcga agctcgagca agccggtcgt ctcgctgcgt ctgaatttct cggcaaagcg
    12781 tcccgacgtc aaattgtctt tcatagaggg agatcggtct gtgaagattg aacacttctt
    12841 ggattcgatt ctccaactca gttgcagcaa gggaatcgac accggcttcc acgaggagtg
    12901 tgctggggaa aatctcgcct ggagaaattc cagctatctc gtgaagcagg cgactcagta
    12961 tagggtcaat atctgagact tcgctgtcat ccgagggccg gcaagctttg gtggccggtt
    13021 cgtataccgc ttctgtctcg actggtagct ccgaagtctg actgttgaga ctggctctct
    13081 tgacgattcc gtcgagggag ctggtggtaa tccgaacgaa cctcgcgcca aggatagcaa
    13141 caatcaattg cttactggtt gagtcaaata caaatgtgtc actcaggagc tccctgggcc
    13201 cgcggagtgt ttgtcgagta taaacagtcc atgggcccgt ctctgatttg agacttttga
    13261 atgtgaccaa ttcattcagg ccagaacaga tgaatacatc atctctcttg caatcgtccc
    13321 tgcaaagtgc cagtacttct gcgatcaacg tgacctggtc catcacgagc ggatcgcaca
    13381 ctgctatttc cgagcagttg cgaccaatct tcggcatctc tagctgggcg actgccgcgg
    13441 tgtcttttat ggtcatggct ttgatgcccc tatagcaagg cttgtactcc gctactttct
    13501 ccagcacttt atatattaag cttcctttca tggaaattgc cgaacggtca tcaatgatat
    13561 cctggatatg gctgtaaccg attacccgct ggatcactga ccactgggaa cccattccgg
    13621 atttgccatg tcgctcctgc ttaagaaaaa tcgttcctgt tgcgtgacat atgctctggg
    13681 cgtttttttc actgatgatc gagaatcccc acttgcatgg tccgacgtgg ttgagcctga
    13741 ggccaacgcg gactcctcga gcgtgcccga gcgggttatg gatttccaga tccagaacct
    13801 gtacatgagc aaacgccatc gagcattcgc ggccgccggg aatggccgca gctttagcgg
    13861 ccagctcgac aaacactgac acaggacaca aaacctcccc aaggacttcg cggccgttca
    13921 ggtacctgct aaagtctgga tgacaatgat tgactccaaa atgcaatttt cgcggttctt
    13981 ctctgaagcc ttcgtccttc agcaaataga ctagtggctt gtgttcgtca gaaatgatca
    14041 tctcctgctc agagtcgctc tgtcccgctt tgtcagaata taaaagccag aatgctgtct
    14101 cgtcaaattg gtaaccagga acatcacaag aggcaaaagt tgacttctct gcgtcatgat
    14161 acagccaaaa ttgcacatca aggccttcat tccacatctg catcgtggtt tctgttagtg
    14221 atgccaaagg ttctgacgaa tccaattgta gtcgatgaaa cgaatgccct gagctgctct
    14281 cgattccgag ggcgcacttc acaagtgcga tgcctctgga tccggcgcct ccttcaaccc
    14341 acgtacaagg gcctaattct tcgttaactc gagaaacagc atcgaagaaa tataccgctt
    14401 cgcgcgaatg acgaacaacc agttcgggag tgaactcctt ccatctaccg cccatggaac
    14461 atgtttcgat tggaatgttc ggcgttgcat atgagatatt ccgtgccaga gccatatagt
    14521 catccagcaa gcagtcaacc atctcaaaat gaaagccgtg ggtagtcttt aatcttcgag
    14581 tcttgcagga tgtcttgcct tcgagggtgt gtatggctac ttcagtgcca accaggacgt
    14641 gattcctagc cccattgaaa catgcaatct ctatcttatg atctgggact gagcgggcaa
    14701 cttcgagagc tccctgcctg tctacctcaa cggcaagcat acagcccctt tctttgcccc
    14761 atttttgctg gataagcctg gctcgccctg caactagctt tagagtatca gcaagtgtcg
    14821 taatgcctga gatacacatt gcagtaaact ggccaatgct atggcctatg acacggtgga
    14881 cgggcaagcc cgcaccaagc caagctgcgg cgcaagcgta ctgcaacgag aagaacaggc
    14941 aatgaaggag caccacatcc tctatgggtt gttggtcaaa caagaatgga atcaggccac
    15001 ggtggcccat cctccggaga atcccgtcgc actcgtcaat gtgtgatcgc aacagccttg
    15061 acccttcata cgcagctttg ggcaggtaga caatgttccc ggtttggcct gcaaagacca
    15121 gaacaacagg cttgggctta ggtgaaggcg acaatagttg ctcatgcggc ctcgccttct
    15181 gtccaagaat gcttctcaat tcacttagcg aacttgcagc gaaggcgatt cgatgtcgaa
    15241 gagtccgatt ctgcctccga gccacattga acgcgatatc tgacaatggt gcgcgggcat
    15301 tgtctaacca gtgactaagg gcagtgcaat acatcttcag actcctttct gactgcccag
    15361 ttatcaaaaa tgggtatgca gagagtctgt cattattgcc agcactggaa tctggccgag
    15421 gtggctcgca aacaatcact gcagcgttgt tgcccgctgc accataattg ttgatgcacg
    15481 cagcacggaa aatggccttc cattcgagtt cattgattgg gaccgacaag ttgtccggtt
    15541 caagtggcgg aatcgatgca ttcaaagcag tgaaattggc ctgtggaggt attcgttgat
    15601 ttcggatcat caacaggact ttgaggagtc ctgcgatgcc tgatgcggct tctgtatgtc
    15661 cgatgttggc tttaacagag ccgaaatgca acgtaggtct cgaaccccca aacacttgtc
    15721 gaatacttct gcattcgact gggtctcccc gcggagtacc ggtgccgtga gcctcaacgt
    15781 aggtgatgtc cttgggttcc atggctgcca gcgacagagc cttgcgatag aggttgacct
    15841 gcgagtgtga tgttgggaca gtaattgcgt cgttgccatc gcaatgattt gctgccgatc
    15901 cgacaatcac gcctagaata tcatcattgt cggccacagc acatgataac ttcttcaaca
    15961 tgacaaagcc acatccttcc ccacggcagt agccatcagc agaagcatcg aacggacggc
    16021 aaggaccagt tggactcaga aacctggctg ccgccaagtt ctcttgcata ttcgggcagg
    16081 agattatgtt gactccccct gccagggcca tgcggcattc gcccatcctg atgtccttgc
    16141 atgcctgatg gatagccaca gctgacgaag aacacgcagt atcaatggtc attgatggtc
    16201 ccgtccaccc aaagtagtga cttatgcgac cgctcacaaa ggctcgagca gtgcctgtga
    16261 atgaaaatgc cgttggggca tgagagcaga cgttatgatc ataatcggaa cctccgacgc
    16321 caacgtagca gccaatattc ttgtctttga tgtggctccc gaagtattca gatgactcaa
    16381 cagcttggta cgccacacgt aatgcaatgc gctgttgcgg gtccatgtaa gtagcttccc
    16441 ttggggatac tccaaagagt ccgtggtcga agtggcctgc atcagacagg aagttgcccc
    16501 tcagtgactt ttcccgaggt gccttgcgca atgacttgtc gaccgcaatt ctgccttctg
    16561 gaaggtcacc gatcgttgtg cctcctgttc gaatgagttc ccagaattgc tgcatagttt
    16621 ctgcaccagt gaatttacaa gcagctccaa tgacagcagt agagtgctcg gggtagtcat
    16681 agcgatgttc atcattcgtt gatgattttt gatctttcgg cgaaacggtc gaggtcaatg
    16741 gcggcgagaa aacttggagg ttggcggatg cggtaagtga ccgtgggaga cagctcacaa
    16801 ggcccaactc caatatgagc ggccgctggt ttttctcagg ctgcgacttc aagctggaaa
    16861 tagtctccgt catggttgag taccagttag ctggctccgt caacacgcat ttcaaggtaa
    16921 gctcatgcag cttctccgcc gatgtgatca ggtccccggt ggtgttattt ctcaatggga
    16981 cgaaaggtgt gttgatgatg gggaaacgta gagactcgtc gttgttgcag atttcaacga
    17041 gatcttgaag aatctcggcg tgtgttatgc tatggtatcg tccgtggatg ggaatattcg
    17101 tcaccttagc gtttcgtgct gccaggtcgg cccgcagtga tgacacctgg gactgtttgg
    17161 ctgtgacggt gatgcttcta tcgtcaagct cgacagacgt gtacacctat tggatgctgt
    17221 tagcttgacc ctgacattgg gtcgccgcgt catgtctcaa tacgcacctc aggataccct
    17281 ttcaggactt ctgttactcg atcctttcca cagttatctt cccaatgtat gatcatacag
    17341 acgtaaacat ctgtgctgtc atacgtcaac ctgtccaggt caacgtagcc acccacgcac
    17401 gtggctaatc tcaatgcgac agtagcgttg cacgatacgt ctctttccgt cctggagcat
    17461 gccagagcag cagcactgag aaagcctgtg caaagcccct gaaatccacc tttacacgtg
    17521 gattgcagaa tacgccgatg tctgtcttct tggaaatcgt cggcattcaa ggagtgcgca
    17581 aatcggagat attgaaccag atgaataatg actgtgagcg gtgctaatag gatgtttggc
    17641 aggtcttctg gtatttccaa caagcactca tccctagccc aatctttcaa cttttgcaga
    17701 ggttcgtcgt tgacttggct caagatgggc ttgatctcaa ccaaacgcga ccaaaactgt
    17761 ggcaggtcat ccactgcctt ggcaagctct ttcaacttcg ggtttttgag atttgatcga
    17821 atgcgctgca ggcactctct tgagggcgga ggggtttgcg agccgcaaac aattatcgat
    17881 gggagtgcta atgccat
//
