BGC0002615 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002615 (Penicillium terrestre)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	24,396	4-oxomacrophorin A/macrophorin A/5'-epimacrophorin B	terpene	100%

BGC0002615 - Region 1 - T1PKS

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Location: 1 - 24,396 nt. (total: 24,396 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,397
Label		BGC0002615

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002615	1.00	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0000170	0.54	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001275	0.37	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273	0.37	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244	0.36	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0002218	0.32	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0002245	0.32	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0002610	0.32	Terpene	stellatic acid	Aspergillus stellatus
BGC0002219	0.31	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000129	0.29	Polyketide	pyripyropene A	Aspergillus fumigatus Af293

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002615	1.00	Terpene	4-oxomacrophorin A, macrophorin A, 5'-epimacrophorin B	Penicillium terrestre
BGC0000170	0.81	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001275	0.70	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001273	0.70	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001244	0.69	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0002218	0.66	Terpene	(-)-Cyatha-3,12-diene	Dentipellis sp. KUC8613
BGC0002245	0.66	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0002610	0.65	Terpene	stellatic acid	Aspergillus stellatus
BGC0002219	0.65	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000129	0.63	Polyketide	pyripyropene A	Aspergillus fumigatus Af293

Similar known gene clusters from MIBiG 4.0

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 24396:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

QBC75448.1

PKS_AT (587..879): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 94.4
Methoxymalonyl-CoA: 72.7
Ethylmalonyl-CoA: 71.1
Malonyl-CoA: 46.6
Isobutyryl-CoA: 46.3
Propionyl-CoA: 32.7
Acetyl-CoA: 30.5
Benzoyl-CoA: 24.4
2-Methylbutyryl-CoA: 24.3
trans-1,2-CPDA: 23.1
fatty_acid: 22.9
CHC-CoA: 16.2
inactive: 0.0
3-Methylbutyryl-CoA: 0.0