LOCUS       BGC0002615             24396 bp    DNA     linear   PLN 20-FEB-2019
DEFINITION  Penicillium terrestre isolate LM2 macrophorin biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0002615
VERSION     BGC0002615
KEYWORDS    .
SOURCE      Penicillium terrestre
  ORGANISM  Penicillium terrestre
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 10:57:46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24396
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..24396
                     /db_xref="taxon:374132"
                     /isolate="LM2"
                     /mol_type="genomic DNA"
                     /organism="Penicillium terrestre"
     misc_feature    1..24396
                     /note="macrophorin biosynthetic gene cluster"
     protocluster    1..24396
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[9263:14615]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9264..14615
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..24396
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..24396
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002615"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24396
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            join(<974..1561,1664..2853,3027..>3810)
                     /product="MacR"
     CDS             join(974..1561,1664..2853,3027..3810)
                     /codon_start=1
                     /note="transcription factor"
                     /product="MacR"
                     /protein_id="QBC75452.1"
                     /transl_table=1
                     /translation="MPLSEPRQIKKPRLSLSCIVCRRRKVRCGREQPECANCVRMKENC
                     VYRTMVRDESTGRVRPVSPQDKDSRVSTSDARPDLPWPHWGRDTNAPYPDKPSRPPSRP
                     QVSANASPSPQRQEPYPTVPSWEEAIQLPSYRDANAPQINGSSTTTRDPSPAPSTSLFP
                     TPSDHPCRDYLSIRRGGRVRYVGQTFWGFVAGKESLSDDFFDENRHAHPDLPLPHISSM
                     GMFNLLRSLPTKPVSDTLLETFFLAVWPLVPLLHPPSLQADYDEFWEWCRNSENALPSD
                     KLRDDPTLICLLFAVLYCGASAAPAATWANTNLQGLQKETTVSHLKSAYTTSLSLCQHQ
                     EHPTLNTLVSNLLTGPFLDRPFEPMRSLVNVSTTVRIAQTMGLHREGAWSALSSVDREI
                     RRRVWWHIVWLDVQSSISTGLTPCCGNEALDAVGMVGTDHVEPSNIPAGLSPPNELVTN
                     RQSVAMLYAIGRFQTARLQARIVAHLQSAHDPSQDGFGELITDSKELLQKIDSLIARVP
                     TQGIPEMGYIPSRLANASPSTQPLLYKDDPSQPTVFSAWTRIMLTLLKSEMAILLQKPF
                     LPPPDSANPQSLKSWTSMAQLCVNYLRIYLQLYQAPAFSPYAWFCCSHYGPLQCVFITL
                     MYLHYFQHSGETTLARYCVDEVIHHCVAQYQAPDPSSTRTSPDDTDSNGGKLRMPLAIQ
                     VLVDLHERLDSSLGPEDRAPPLDLIECQARFSMSHLATKASDLRATSDQPSSDVSSTTR
                     THHNCETPPITTGAPPVAAGNKPVPPNSVFVAGSDSGLDMDFLATISDLEAWSSSLILE
                     SDNLLARPDDMTPDHAVITRLGSQSTASGRRGLPDGLDFPG"
     mRNA            complement(join(<4309..5755,5809..5872,5934..>6033))
                     /product="MacC"
     CDS             complement(join(4309..5755,5809..5872,5934..6033))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 209.4; E-value: 1.6e-63)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="MacC"
                     /protein_id="QBC75451.1"
                     /sec_met_domain="p450 (E-value: 8.8e-83, bitscore: 268.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MALLYITTAALALLLLFLRAVFKSWRIQRKLPPGPPGLPLIGNIH
                     QIPAVRAHQKFTEWAKVYGGLYTFRIGPATAAVITDRGLVKELLDKRSALYSSRPVSYV
                     GQNLITGGDHLLLMDNNEMWRLFRKTVHQHFKASMCEKEHVKLLEAEHTQMMRDFLLYP
                     EKHMLHTKRTTNSIIMSLLYGIRTPSWDTPHMRELYEIMEQWSKVMETGATPPVDIFPW
                     LRWIPQRWLGNWVDRSVEVGSGMKALYGSFRRRAIEARREAEQSSQSRARTFIDHVLDL
                     QEKANLTDNQVDFLGGVMMEGGSDTGSTMLLVMIQALVRYPEVQERARAELDAVCGEGR
                     SPTWADFSRLPYINMIVKETMRWRPVTPLSFPHALNQDDWVNGYLLPKGTTVFLNVWGL
                     HHDESIFPNPERFDPSHYEGRHNLASDYAASPDYMQRDHFIYGAGRRLCPGIHLSERSM
                     FIGAAKLLWCFQFEPEMDESGRPVAIDTDPITGYTEGFLVCPQAYKCKVSPRSTARAET
                     IMREFAQAESEVLCQYATP"
     mRNA            complement(join(<6433..7397,7453..>7504))
                     /product="MacB"
     CDS             complement(join(6433..7397,7453..7504))
                     /codon_start=1
                     /note="metallo dependent hydrolase"
                     /product="MacB"
                     /protein_id="QBC75450.1"
                     /transl_table=1
                     /translation="MNRIDVHHHFIPPAYVKAFNSTPGDPSGWHLPKWTPESTLSLMAS
                     HSTRTAILSLTAPGTSIMSNSPVESANLARQINLYGFQLHQENPTRFGFFASLPHLTPE
                     TIPSAVEELAYALDTLQADGITLYTRYSGTGYLGHAAFAPLWEELNRRKAVVFIHPTNT
                     ASDAQNKPEMVNPKLPQPIIDYPHETCRTAVDLITSGTISKNPDVKIILSHGGGTLPIL
                     ATRAANLLYDAGLTEITPETFLEQARSFYLDLALSGNVGNLELLVGKNGFAKPGHVLYG
                     SDFPYAPVETINKYVGMMEEFFAQGGDKEEVARGAAAELFPRFRIEDNKEMIPQNRL"
     mRNA            complement(join(<7786..8515,8569..>8798))
                     /product="MacG"
     CDS             complement(join(7786..8515,8569..8798))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /note="prenyltransferase"
                     /product="MacG"
                     /protein_id="QBC75449.1"
                     /sec_met_domain="ubiA (E-value: 2.9e-32, bitscore: 101.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTVSTTPKSQRNVARGVWELARLHTREAWLCWYPAIWGACVAAGM
                     RDVSLELAPFLRLLFGIWASVTATHCAFCTFNDICDQKLDKHVERCKIRPLPSGMISTS
                     EAVVAFICWLPVTLAITWGTLGPAVMAGFIPVWVLSTIYPFMKRIMPFPQVVLGAIIGG
                     AVFPGWVGITGDLKDLDQALPLFFATASWVVYFDVFYATQDRPDDEKIGVKSLAVLLGK
                     NVQILLAVLGALQVLLFAVTALRADMSLIFWVLGLGVWMVNVPWHILSLDLKDRHSGGR
                     IFKSNIKLGLYLTGVSLLELFVVRVYDISLANMKMELH"
     mRNA            <9264..>14615
                     /product="MacA"
     CDS             9264..14615
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (47-475). E-value:
                     3.1e-156. Score: 512.4. Matches aSDomain:
                     nrpspksdomains_QBC75448.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (587-879). E-value: 2.9e-71.
                     Score: 232.1. Matches aSDomain:
                     nrpspksdomains_QBC75448.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (948-1067). E-value: 6e-12.
                     Score: 38.1. Matches aSDomain:
                     nrpspksdomains_QBC75448.1_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1418-1612). E-value: 6e-56.
                     Score: 181.1. Matches aSDomain:
                     nrpspksdomains_QBC75448.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1699-1778). E-value: 2.8e-15.
                     Score: 48.3. Matches aSDomain:
                     nrpspksdomains_QBC75448.1_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 106.9; E-value:
                     1.7e-32)"
                     /gene_kind="biosynthetic"
                     /note="polyketide synthase"
                     /product="MacA"
                     /protein_id="QBC75448.1"
                     /sec_met_domain="PP-binding (E-value: 6.4e-12, bitscore:
                     35.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 6.1e-157, bitscore:
                     512.4, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.9e-72, bitscore: 232.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.4e-54, bitscore:
                     174.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MITSTSSTEVLTPANGSDDSKGTTTPATSSGDPEMHDDLLRNDTH
                     DDVAIIGMACRVPGDVNSPSALWQFLLEKGDASGDMPTWRWDPYRQRHPRNAAVLAETT
                     AKGYFLNDIDQFDAAFFAISPREAEQMDPQQRIALEVAWEALENAGISPSRLAGSNTSV
                     YMGVNSDDYAKLVLEDLPDVGAHMGVGTAYCGIPSRISYLLDLMGPSVAMDAACASSLV
                     AVHHARQAIRAGETDLAIAGGVNALLGPGLTRVLDEAGAISADGKCRSFDDSASGYGRG
                     EGAGVVILKRLDKALTDGDQVLAVLKGSAVASDGKTLGIMAPNAQAQLLVAQKALKEAK
                     VTSDSINYIEAHATSTSLGDPTETNALAEVYGVGSGRHPSDPCYIGSIKPNIGHLEAGA
                     GVMGLIKAVLVLRYGEVPPQANLQTLNSKIAWKENLLRPARELVTLPRGALSRPLRAAI
                     ASYGYSGTVSHAIIEAFAGQSLFAERLAQIPDSDAAPALLLLSVPQANRISTTAAGLSR
                     WLRDMDGAVSLATVASTLSQRRMHHRFRHAIVADSVANAIATLDDLAKDVPSRWAISDR
                     IGSEAGKGAVWVFSGHGAQWPDMGRELFHSSPAFGEVVRNLEPIIQAELGFSAIETLHA
                     GCPDRTDLIQAMTFLMHLGIAAVLEAESGPPTAVVGHSLGEAAAAVVSGALTWHEAALV
                     VCRRARLYREFMGQGAMALVRLSASEARARIATHPGASVAIETSPTACVVSGTVDALQR
                     LSEQWLEEGVEVRAVATDVPFHTPLLEKLAGPLRGALKNELHPQVPHRALYSTSLLDPR
                     SDLLRDAEYWVMNMIQPVLLQSTVAALVDDGFRAFVEVASHPIITHSIVETISEQTTDR
                     FIATPTMVRKQPALKSILAAVGRLHCFGCAVKPTDLDPTVPWSSSVPGTIWHHQSFYRA
                     VSGMTAAQLASTHKPAANDLLGTRTALWGTEEVLYQTRLEEDNRPFPGRHPLHGSEIVP
                     AAVLLRTFLRALSPRSVEEVSLQVPVVVSPAREIQIRHNTRNITITSRLEESTSNEHNS
                     WLVNTTATVGADATPSVSHVDIAEVAKRLPQKLSDSFSIDYLASVGVSAMGFPWRVAHH
                     VASDNEMLARVHANPDSLPGMDDLLTSVMDAATSIASTLWHSKPRLRMPTAVRRVVAVG
                     VATPQVVYIHCTKAQSSVDEADVIISSEEGMVLMEIQGMAFAGVEGESLSRKSTSGLVH
                     QISWPPAALAEEPLEFAHIAFLTADATKAQVGTYQRQIEGRGISTSIHERASDLPLTTH
                     SSMAVVYLPQFTDRIFDTATRSCNDLVTAAQVILSSSDKPTIRLFAVTSESNLGHSALT
                     GLGRILHTEHPEIWGSLIDLEDPSVFPLMAMRYVRNADVIKIEDGVPRTARLRPLRPAP
                     PHSTAGPATLTFSPASTYLITGGLGSLGISVAQWMVTQGARRILLLSRRSLPPRSIWTA
                     SHKPGTQFIIDSILSLERLGATIHPVAIDISHPSAVTNLRSALTTLSLPPVAGVVHAAG
                     ILRDQLIEQITPDAFEAVLAPKIAGALALHTVFPPSSPDLDFFVLFSSCGQLLGFPGQA
                     SYASGNSFLDALARSRRKEGDNAISLLWTSWRGMGMGASSNGALEAELYARGITDVTPD
                     EAFLAWSSISGTEGADHGVVLRARPLESGEPLPHAILRDIAPRKEKAVGEGNGENEEQR
                     KKLSGKELAEYVLVVVKKCVSTTLSIPEDEVDETVALPEMGMDSVMTVNFRMSLQQTLT
                     VSVGPTLVWKYPTVHHLVEYFCQVLDE"
     aSDomain        9405..10688
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBC75448.1_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="3.10E-156"
                     /label="QBC75448.1_PKS_KS.1"
                     /locus_tag="QBC75448.1"
                     /protein_end="475"
                     /protein_start="47"
                     /score="512.4"
                     /tool="antismash"
                     /translation="VAIIGMACRVPGDVNSPSALWQFLLEKGDASGDMPTWRWDPYRQR
                     HPRNAAVLAETTAKGYFLNDIDQFDAAFFAISPREAEQMDPQQRIALEVAWEALENAGI
                     SPSRLAGSNTSVYMGVNSDDYAKLVLEDLPDVGAHMGVGTAYCGIPSRISYLLDLMGPS
                     VAMDAACASSLVAVHHARQAIRAGETDLAIAGGVNALLGPGLTRVLDEAGAISADGKCR
                     SFDDSASGYGRGEGAGVVILKRLDKALTDGDQVLAVLKGSAVASDGKTLGIMAPNAQAQ
                     LLVAQKALKEAKVTSDSINYIEAHATSTSLGDPTETNALAEVYGVGSGRHPSDPCYIGS
                     IKPNIGHLEAGAGVMGLIKAVLVLRYGEVPPQANLQTLNSKIAWKENLLRPARELVTLP
                     RGALSRPLRAAIASYGYSGTVSHAIIEAF"
     aSModule        9405..14597
                     /complete
                     /domains="nrpspksdomains_QBC75448.1_PKS_KS.1"
                     /domains="nrpspksdomains_QBC75448.1_PKS_AT.1"
                     /domains="nrpspksdomains_QBC75448.1_PKS_DH.1"
                     /domains="nrpspksdomains_QBC75448.1_PKS_KR.1"
                     /domains="nrpspksdomains_QBC75448.1_PKS_PP.1"
                     /iterative
                     /locus_tags="QBC75448.1"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       9885..9932
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0001"
                     /evalue="9.90E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="QBC75448.1"
                     /protein_end="223"
                     /protein_start="207"
                     /score="14.7"
                     /tool="antismash"
                     /translation="GPSVAMDAACASSLVA"
     CDS_motif       10050..10073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="QBC75448.1"
                     /protein_end="270"
                     /protein_start="262"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="SADGKCRS"
     CDS_motif       10074..10112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0003"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="QBC75448.1"
                     /protein_end="283"
                     /protein_start="270"
                     /score="11.8"
                     /tool="antismash"
                     /translation="FDDSASGYGRGEG"
     CDS_motif       10305..10352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0004"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="QBC75448.1"
                     /protein_end="363"
                     /protein_start="347"
                     /score="9.6"
                     /tool="antismash"
                     /translation="YIEAHATSTSLGDPTE"
     CDS_motif       10419..10463
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0005"
                     /evalue="6.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="QBC75448.1"
                     /protein_end="400"
                     /protein_start="385"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSIKPNIGHLEAGAG"
     CDS_motif       11019..11072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0006"
                     /evalue="1.20E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="QBC75448.1"
                     /protein_end="603"
                     /protein_start="585"
                     /score="17.7"
                     /tool="antismash"
                     /translation="VWVFSGHGAQWPDMGREL"
     aSDomain        11025..11900
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBC75448.1_PKS_AT.1"
                     /evalue="2.90E-71"
                     /label="QBC75448.1_PKS_AT.1"
                     /locus_tag="QBC75448.1"
                     /protein_end="879"
                     /protein_start="587"
                     /score="232.1"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFSGHGAQWPDMGRELFHSSPAFGEVVRNLEPIIQAELGFSAIET
                     LHAGCPDRTDLIQAMTFLMHLGIAAVLEAESGPPTAVVGHSLGEAAAAVVSGALTWHEA
                     ALVVCRRARLYREFMGQGAMALVRLSASEARARIATHPGASVAIETSPTACVVSGTVDA
                     LQRLSEQWLEEGVEVRAVATDVPFHTPLLEKLAGPLRGALKNELHPQVPHRALYSTSLL
                     DPRSDLLRDAEYWVMNMIQPVLLQSTVAALVDDGFRAFVEVASHPIITHSIVETISEQT
                     TDRFIATPTMV"
     CDS_motif       11259..11360
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0007"
                     /evalue="2.90E-12"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="QBC75448.1"
                     /protein_end="699"
                     /protein_start="665"
                     /score="38.8"
                     /tool="antismash"
                     /translation="PTAVVGHSLGEAAAAVVSGALTWHEAALVVCRRA"
     aSDomain        12108..12464
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBC75448.1_PKS_DH.1"
                     /evalue="6.00E-12"
                     /label="QBC75448.1_PKS_DH.1"
                     /locus_tag="QBC75448.1"
                     /protein_end="1067"
                     /protein_start="948"
                     /score="38.1"
                     /tool="antismash"
                     /translation="DLLGTRTALWGTEEVLYQTRLEEDNRPFPGRHPLHGSEIVPAAVL
                     LRTFLRALSPRSVEEVSLQVPVVVSPAREIQIRHNTRNITITSRLEESTSNEHNSWLVN
                     TTATVGADATPSVSH"
     CDS_motif       13518..13616
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0008"
                     /evalue="9.40E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="QBC75448.1"
                     /protein_end="1451"
                     /protein_start="1418"
                     /score="50.3"
                     /tool="antismash"
                     /translation="TYLITGGLGSLGISVAQWMVTQGARRILLLSRR"
     aSDomain        13518..14099
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBC75448.1_PKS_KR.1"
                     /evalue="6.00E-56"
                     /label="QBC75448.1_PKS_KR.1"
                     /locus_tag="QBC75448.1"
                     /protein_end="1612"
                     /protein_start="1418"
                     /score="181.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYLITGGLGSLGISVAQWMVTQGARRILLLSRRSLPPRSIWTASH
                     KPGTQFIIDSILSLERLGATIHPVAIDISHPSAVTNLRSALTTLSLPPVAGVVHAAGIL
                     RDQLIEQITPDAFEAVLAPKIAGALALHTVFPPSSPDLDFFVLFSSCGQLLGFPGQASY
                     ASGNSFLDALARSRRKEGDNAISLLWTSWRG"
     CDS_motif       13941..14051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_QBC75448.1_0009"
                     /evalue="3.50E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="QBC75448.1"
                     /protein_end="1596"
                     /protein_start="1559"
                     /score="64.6"
                     /tool="antismash"
                     /translation="LDFFVLFSSCGQLLGFPGQASYASGNSFLDALARSRR"
     aSDomain        14361..14597
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_QBC75448.1_PKS_PP.1"
                     /evalue="2.80E-15"
                     /label="QBC75448.1_PKS_PP.1"
                     /locus_tag="QBC75448.1"
                     /protein_end="1778"
                     /protein_start="1699"
                     /score="48.3"
                     /tool="antismash"
                     /translation="LSGKELAEYVLVVVKKCVSTTLSIPEDEVDETVALPEMGMDSVMT
                     VNFRMSLQQTLTVSVGPTLVWKYPTVHHLVEYFC"
     mRNA            complement(join(<14819..14978,15030..15310,15395..15715,
                     15775..15983,16055..16467,16520..>16668))
                     /product="MacH"
     CDS             complement(join(14819..14978,15030..15310,15395..15715,
                     15775..15983,16055..16467,16520..16668))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 308.7; E-value: 1.2e-93)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="MacH"
                     /protein_id="QBC75447.1"
                     /sec_met_domain="p450 (E-value: 2.2e-63, bitscore: 204.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MALLSVLPVSLWLIAAGTFAVYHAIRAVYLIFFSPLAVFPGSPWA
                     ALGEYWEAYWNIGVKPGRKGQMLFKLEEMHKRLGPALRMGPNEVHIYDPAFYHELYRPG
                     SRYYKDPSMHKVLGAPSSTLAESDPVRHKQRKAPLEPLFSKKNILSLEPMLMEHVDRCS
                     QRFDELFAQGKPVSMEWALKSLAMDMVSQFAFGQSLNALADPEFKSLPVRVFQQYLPSL
                     HVIKAFPFVRLLNSLPLWIAKRISHSVEMGHELEQFAARRIDEYMAAAAAGKTPTFPTL
                     MERLLIPIPEKGYAVPDKQGLRDELLTVISAGDDTTGIANTVTLFNIFNNREVHDRLLA
                     ELKTVMPTPNSHVSYLQLEALPYLTAVIKEGLRYSSPAASRTPRLVPPGGVRLPDGRFI
                     PAGTRVGMAIYHIHYNETLFESPRVFDPERWLQGPEVTAERAKFLVPFSRGSRSCLGIN
                     LAYMEMYMAIAYIVRRFDLDLVGTTEEDMKWDDMVVPQFHGEFMALTKRRED"
     mRNA            <16876..>18171
                     /product="MacI"
     CDS             16876..18171
                     /codon_start=1
                     /note="membrane bound O-acyltransferase"
                     /product="MacI"
                     /protein_id="QBC75446.1"
                     /transl_table=1
                     /translation="MAEMDVSSWKPTKLETKPFSLDSGHYTALAFVLAVCVPQAPHGTA
                     LRYGLLLLQITCGVQAFLAQPPSVPDRAVLYTSGVLMGNLVARYFDRLYTTVPEKTFHR
                     IIDSQTPEDTTQLSAPKRFFWALELFSVTRGIGWNWRVAGIPKSPVPITRFQFAAAQLL
                     RWTVMYAGLHLVNVTCQVVSSNPNAIPSLPGNLHIYALIVCGFAITIYSHFAILMLPLS
                     ALCVGLQVGPRSWQAVASWPPNFGSVREAYSIRRFWGYTWHQQLRRQAGAPGAYLISLL
                     PDSVMTSKRTAVKLARRYSLLMMSFVISGLIHACGTYQVTRALGLPLSDGGEMKYFALQ
                     GMAIIAEDFGCWVLGIDDRGTQPGVMRRWMGYAITLSWYIWSRVQLKGVPVALAMGIED
                     ERGDLFAALELVRVSAVAVPGNFVAMAWELIW"
     mRNA            complement(join(<18353..18464,18531..>19411))
                     /product="MacD"
     CDS             complement(join(18353..18464,18531..19411))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     119.7; E-value: 2.4e-36)"
                     /gene_kind="biosynthetic-additional"
                     /note="short chain dehydrogenase"
                     /product="MacD"
                     /protein_id="QBC75445.1"
                     /transl_table=1
                     /translation="MVNIIQPKVDPLPTGIGLTGKTVVITGASAGMGLEATKQLLRLRA
                     STVILAVRNVAKGEACATSLRQDRRIQTHNPKPTIKVMELDVDDYHSVQRFSKQLREEI
                     PVVHILILNAGIGLLKLERSASGHDRTTQVNYYSNVLLIAELLPYLQAGAEKTGSPARI
                     SWVGSRAHEVTSLEKKAPIKPGEGVLAHMDKEEAFVPFQRYGDSKLLCVMFMYNLAPRL
                     DPKKVIINMMCPGMVNTNMSDVLPMHLRLIVNVVKSFRARPVEVGGWIILNSALVVGPE
                     SHGKFLNDKTISDKSAFIKSPAGQEIQKKLWEETINEIGTLTTLPAELK"
     mRNA            join(<19857..20351,20404..>20691)
                     /product="MacE"
     CDS             join(19857..20351,20404..20691)
                     /codon_start=1
                     /note="cupin fold family protein"
                     /product="MacE"
                     /protein_id="QBC75444.1"
                     /transl_table=1
                     /translation="MAPCKPRTFTAGQDPLTKFDGAISVRNLPRPPDRLFLFHGIMRPS
                     RGIYAKLIATGQKPPTHFHPSQWEFFRVLRGNLTIDFNGRAIHRTASDGELAVPPYTHH
                     VIYGTPGTEMNEVEFVVSASDPAAEEQGATVMDQPFFENWYGYQEDVFQRGEKLDFIQV
                     LSMFDAGGTYLSPPWWVPFRSWVGLFLGIVVGRWIGGLLGYAPFYPEWTTDWEAACETM
                     QQSWFQRRFADPQAQERAREKFRGQLEQEASAKGGKSE"
     mRNA            complement(join(<20889..21111,21168..>21721))
                     /product="MacJ"
     CDS             complement(join(20889..21111,21168..21721))
                     /codon_start=1
                     /note="terpene cyclase"
                     /product="MacJ"
                     /protein_id="QBC75443.1"
                     /transl_table=1
                     /translation="MCFFALEEWAAANRDYENTPAPYWHVKSVPDGFTAISGILWSISY
                     ILMAKKAFKDRSYAMPLHCLCLNITWEAVYGFVYGPGLLNQVVFAQWMIVDVVLFYAIL
                     RSAPYAWKQSPLVAQHLAGIIVVGCVICLWLHLAIAATFIPSIGRQVVFMTAWPMQVLI
                     NFSSIAQLLSRGNTLGHSWGIWWTRMLGTIAAACCFFWRIHYWPERFGYAWTPYGKFLL
                     LGSIGSDMVYAAVYVYVQRIEKQLDSLVNTKAQKAR"
     mRNA            join(<22064..22652,22701..22859,22912..23445,23507..>23784)
                     /product="MacF"
     CDS             join(22064..22652,22701..22859,22912..23445,23507..23784)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 156.7;
                     E-value: 2.3e-47)"
                     /gene_kind="biosynthetic-additional"
                     /note="flavin dependent dehydrogenase"
                     /product="MacF"
                     /protein_id="QBC75442.1"
                     /transl_table=1
                     /translation="MTKMTSIIGILMGVLTTATAASIPTGSSAAAAAALGSLGVSPPSG
                     NVLIGNAGYTCSLLNRVLSKNETFTVTSPYYDVLIDEAWSENCRLNASCIVTPESAEEV
                     SRLLQILSILETRFAIRSGGHNTNPGFSSIGSDGVLIALEKLDSISLSADRGTVTVGPG
                     NKWESVYKYLQPYNLTALGGREAVVGVGGYILGETGGLSTFYNTHGLAIDSVTRFQVVL
                     PNGTIVDATPTEHADLYKGLKGGLNNFGIVTEYDLTTNTGVDIYYEIKTYTTANTPAVL
                     AAYATYLLDADINSNVEIQINPSYTLVFYGYLGHVSAPTDFDPFSDIPVASTMYPPTNG
                     SLTELLLSIGSTGLTSEGVSYSGTFSFKVTGSTFLQDTYSTYLEAAASLPTGAVLSYVP
                     QGVIPNLVTQGKSQNGGNLLGLDATPQVWANIFVQFPATLSQSEVAGSVDSLLANLISS
                     AKSEDLFLPYIFVNDAGAKQKPLQSFGEKNIKYIDTVAKRYDPKRIMQRLQNQAYFVLE
                     EL"
ORIGIN
        1 tcttccaagg ttctcatggc aatgcttatc tcatatctca ctatctcacc ccgagaggcc
       61 tagaatggag tccgataatc atggttttgc atcttatcct gtaagttatt ttagacctag
      121 ataatggcta atttgaaggt agtcgtgagg gtgtgagggt tgtccgtctt tttgtttacc
      181 cttctgggat attgactgaa gaccttgacc tgaatttccg tggaccagtc tatttttata
      241 tttcaatggc tgaagcctgg cgaatttaag tgaacgaagg gctggaaatg agaccttgtc
      301 agccaagtcc ctcgtattac tacggattcc gtggaaatga ggaattatca tattgcatca
      361 ttcgtgatca tttgtactaa tttaatatta atttaatacg gccccaacct atccagacgc
      421 ggccatccga ttcatggtgt gaacaataca gcggttgaag gccaagagat ccagatatac
      481 tctgtattct gtcctccctt agcagtttcg ggcttttaat ctccaatatc aagccataaa
      541 tctcacagat ctctcggcgc tgggctgagg aacaactgaa cctggatttt tcacaatacg
      601 gggggcttat actagtatgt tttgaagtat acccgtaagc actacagatg tactttgatg
      661 agctataaca cgaagatgac atggccccca acctttccta cctattacag agagtgtgaa
      721 ttcatttaaa tttattttat tttatatttt ttattccttc aacaccaact tgtcaaatat
      781 cgttcaggtc tggtggaatg aaatgattgg tcagacggtt atctagccct ggaggtaatt
      841 gggggctaaa ccgccctggc tatcccaacc ctgcatttat cctcctctct ggatacaaac
      901 tccaatatga ttacaataaa aacccacctc ccctcagaag gagtcgaaca ttcgtccact
      961 ccctttctga aacatgcctt tatccgagcc ccgacaaatc aagaaacccc ggctatcgct
     1021 cagttgcatc gtctgccgac gacgcaaggt tcgctgcggt cgcgagcagc cagaatgcgc
     1081 caactgtgtg cgcatgaaag agaattgtgt ctaccggacc atggtccgtg acgaatccac
     1141 cggccgcgta cgaccagtat caccgcaaga caaagactcc agagtctcta catcggatgc
     1201 ccgtccagac ctcccttggc cgcattgggg ccgagacacc aatgccccat atcccgataa
     1261 gccgtctaga cctccttctc gtcctcaagt atccgccaat gccagtccat caccgcaacg
     1321 acaggagcca tatccaacag tcccttcgtg ggaagaggct atacaactcc caagttatcg
     1381 cgatgcgaat gctcctcaaa tcaatggtag ctcgacaacc acccgcgatc cctcccctgc
     1441 gccatcaaca agtttattcc cgaccccaag tgaccatccg tgccgtgatt atttgagtat
     1501 acgacgaggt ggtcgcgtgc gatacgttgg tcagactttc tgggggttcg ttgccggaaa
     1561 ggtcagtctc gctcgtggaa caaaaagaaa gacggaaatg caatctgcga cgggatgtgt
     1621 cgctcggcag gaccatgact gacctcaatt gatcatcctg taggaaagcc tgagcgatga
     1681 tttcttcgac gaaaaccgtc atgcccaccc cgatctcccc cttccacata tttcctcgat
     1741 ggggatgttc aatctcctgc ggtcgctgcc gaccaagccc gttagtgata ccctgctcga
     1801 gacttttttc cttgccgtat ggccacttgt tcctcttcta cacccgcctt ccctccaggc
     1861 agactacgac gagttttggg aatggtgtcg gaatagcgag aatgctttac cctcggataa
     1921 actccgcgat gacccaacct tgatctgcct gctctttgca gtcctatact gtggcgcatc
     1981 tgccgcgccg gcagccacct gggcgaacac caacctgcag ggtctacaga aggagacgac
     2041 agtgagccat ctcaagtcgg catatacaac gagtctttct ctatgtcaac atcaggaaca
     2101 tccaacgtta aatacgctgg tttcgaattt gctgacagga ccgtttctgg atcggccctt
     2161 cgagcccatg cgtagcctgg ttaacgtgag caccacggtg cgcattgccc agactatggg
     2221 gttacatcgg gagggagcat ggtctgcgct gagttcggtt gatcgagaaa tccggcgccg
     2281 agtctggtgg cacattgttt ggcttgatgt gcagtcgagc atctccacgg ggctaacccc
     2341 ctgttgcggg aacgaggcct tggatgcggt gggcatggtt ggcactgacc atgtagagcc
     2401 gagcaatatc cccgctggac tttccccacc caacgagttg gtgaccaaca gacagtcggt
     2461 agccatgcta tatgctatcg gacgcttcca gactgctcgc ttacaggcca ggatcgtggc
     2521 gcacctgcag agtgcgcatg atccaagcca ggatggattt ggcgagctga tcacagattc
     2581 caaggagctt ctgcagaaga ttgactcgct tatcgcacgc gttccaacac agggaatccc
     2641 cgaaatgggc tacatccctt cccgcctggc gaatgcgtct ccgtccaccc aacccttgtt
     2701 gtacaaggac gatccaagcc agccaaccgt cttctcggca tggacgcgaa tcatgctaac
     2761 attgctgaaa tcagaaatgg ctattttatt gcagaaacct tttctgccac ccccggacag
     2821 tgcgaacccg caatctctca agtcatggac caggtatgga tcatttctct acatttcatc
     2881 cctatctcgc atgttataat gcatctccca gtgcatccct ttccgcacag cgaatcctgc
     2941 ctagcttaat taattatcca tttttattga tccaccaacg tcatactacc atgaaagact
     3001 tattgacacg cgatttgacc atccagtatg gcgcagctct gcgtgaatta cttgcgtatc
     3061 tacctgcagc tgtatcaagc tcctgccttc tccccatacg cgtggttctg ctgcagccac
     3121 tatgggcctc tccagtgcgt attcatcacc ctaatgtacc tccattactt ccagcactct
     3181 ggagagacca cgctggcccg atattgtgtt gatgaggtta tacatcattg cgtcgcccag
     3241 tatcaagctc cagatccttc ctcgacgagg actagccccg acgatactga ttccaatggg
     3301 ggcaaactgc gaatgccatt ggccattcag gttctcgttg accttcacga acggctcgac
     3361 tcttctctcg gacctgaaga cagggctccg ccactagacc taatcgagtg tcaggcccgc
     3421 ttttctatgt ctcaccttgc taccaaggcg tccgacttgc gcgccacgtc cgaccagccc
     3481 tcttctgatg tatcgtctac cactcgcacc caccacaatt gcgagacgcc acccataacc
     3541 accggggctc ctccagtggc tgctggtaac aaaccagtcc caccgaacag cgtctttgtg
     3601 gctgggagtg actcaggctt ggatatggac ttccttgcta cgatttcgga tcttgaggcc
     3661 tggtcctcgt cattgattct ggaatccgac aatctcctcg cccgtcctga tgatatgacg
     3721 cctgatcatg ctgtaatcac acggttaggc tcacaaagta ccgcgtctgg tcgccgtggc
     3781 ctgcccgacg gactcgattt tccagggtaa caggctaatt tctatgctct tctttttgct
     3841 tttgttgtcc atatcgtaag caaaaatcaa tgtatagagt atataagcaa tttttacacg
     3901 gctccagcgg cttcttcctt taattacacg atttgacctg attctagaat atcagtgact
     3961 ccatgggacc cctcaggagc ctgcactgca agatccggca ttctcccttt acggacacca
     4021 acaacgctac tgcaccaaca cggacctctg cggacattta gcgagatctc acctgcatac
     4081 acgtgcatat acgcaatccc gatacaacca tttcctcgca cccagcttcc aatgacatcg
     4141 catgaatttg catcattcgg aaacgtgtag tatgcacacc atcgcttaca cggtccactc
     4201 tccgtgtcga tgtgagccaa agtatattat atatcccagc atcggccgag taatccattg
     4261 tcggccttga ctcagcagtc ctcggacttg ccctctcggc ctcgcagctt acggcgtcgc
     4321 atactgacaa aggacctcgg actcggcctg ggcgaactcg cgcataatcg tctcggctct
     4381 cgcagtggaa cgaggggaga ctttacattt gtacgcctgc ggacacacaa ggaatccctc
     4441 ggtgtaccca gtgatcgggt cagtgtcgat tgcgaccggc cttcccgact cgtccatttc
     4501 gggctcgaac tggaaacacc ataggagctt ggctgctccg atgaacatgc tgcgctccga
     4561 cagatggatc cccgggcaca gccgtcgtcc agccccgtag atgaagtgat cccgctgcat
     4621 gtagtccggc gaggcggcgt agtctgaagc cagattatgt cggccttcgt agtgactcgg
     4681 gtcgaaccgc tcgggatttg ggaatatgct ttcgtcgtgg tggaggcccc acacgttcag
     4741 aaacactgtc gtccccttcg gtaggagata cccattcacc cagtcgtctt ggttgagcgc
     4801 gtgcgggaat gatagtggcg tcaccggccg ccagcgcatc gtctctttga cgatcatgtt
     4861 gatgtacggc aaacggctga aatccgccca tgtcggggat cggccttcgc cacagacggc
     4921 atcgagctcg gcgcgcgcac gctcctgtac ttccggatac cgcaccagcg cctggatcat
     4981 taccagaagc atcgtggacc cggtatcgga cccaccctcc atcatcacgc cacccaggaa
     5041 gtccacttga ttgtcagtga ggtttgcctt ctcctgtagg tccaggacgt gatcaatgaa
     5101 agtccgagct ctgctttgtg aactctgctc ggcctctcgt cgtgcttcga tcgcccgtcg
     5161 ccggaaggac ccatacaatg ctttcatgcc gctgcccact tctaccgacc gatcgaccca
     5221 gttgcccaac caccgctgtg ggatccatct cagccacggg aagatatcga cgggcggcgt
     5281 ggcacccgtc tccatgacct tggaccattg ctccatgatc tcgtagagtt ctcgcatatg
     5341 tggtgtatcc cacgacgggg tacgaattcc gtacagcaga ctcatgatga tactgtttgt
     5401 ggtgcgcttc gtatgcagca tatgtttctc cggatacagg aggaaatcgc gcatcatctg
     5461 cgtgtgctcg gcttcgagaa gcttgacgtg ctccttctca cacatgctcg ccttgaaatg
     5521 ctggtgcact gtcttgcgga atagccgcca catctcgttg ttatccataa ggaggagatg
     5581 gtcgccgccg gttatgagat tctgtcccac gtaggatact gggcgtgagc tgtatagggc
     5641 gctgcgtttg tcgagcagtt ccttgaccag accccgatcg gtgatgacgg cggcggtggc
     5701 tgggccaatt cggaaggtgt agagaccgcc atatactttg gcccattcgg tgaatctgtt
     5761 gatgttagat ggggttgtag ttaattcggt acatgaggag aaaccaactt ttgatgcgcg
     5821 cgtactgcgg ggatctggtg gatgttgcca atgagaggca ggccaggtgg acctggaatt
     5881 cgttagcttg gtattttctt ggactggaat agagagatga attagataag taccaggagg
     5941 tagtttgcgc tgtattctcc aacttttgaa gacagcccgg aggaagagta acagcagcgc
     6001 cagcgctgcg gtggttatat acaagagtgc catggtagtt gctcaacact tccaatctaa
     6061 cccatgggga tttttcagat agaataagag ctaggagtct gtgaagcgac actatactga
     6121 tgtatagaga tggcagggat acgagaataa atactcctgg gattacgata caatcaccac
     6181 aggacatcaa gtcggccgac atagtatact cggatgtccg aaaaagggac tgtattgacc
     6241 gagatgatac actagcatgc tgatcatact ttgcgaggga tattgatgga ttctacaagt
     6301 gtgagattgc gcggcctttc tcttggagat ccaattagcc ctaccaacaa acttatatag
     6361 atcctttctc gtatagcatc ctggaatgat gattcattcg tctctgcata cctccgtata
     6421 tacgcatata gcctatagcc tattctgagg aatcatctcc ttgttatcct caatccgaaa
     6481 tcgggggaat aactccgccg ctgcgccccg ggcgacctcc tctttatccc ctccttgggc
     6541 aaagaactcc tccatcatcc caacgtactt gttgattgtc tccacgggag catacggaaa
     6601 gtcactgcca tatagcacat gacctggctt tgcaaaccca ttcttgccca ccagtaactc
     6661 caaattcccc acgttcccgg aaagggcgag gtcgagataa aagctcctgg cctgctccag
     6721 aaatgtctcc ggtgtgatct cggtcaaacc tgcatcgtaa agcaggtttg ccgcgcgagt
     6781 agcgagaata ggcagtgtac cgcctccgtg ggacagaata atcttcacat cggggttctt
     6841 agagatcgtc cctgaggtga tcagatcgac cgccgttcga catgtctcgt gtggataatc
     6901 gattattggc tgtggcagtt tcggattgac catctccggc ttgttttgtg cgtccgaggc
     6961 cgtgtttgtc ggatgaatga agactactgc tttgcggcgg ttgagttcct cccagagcgg
     7021 cgcaaaggcc gcatgaccca ggtatccagt tccactatac cgagtataga gagtaatacc
     7081 gtccgcctgg agggtgtcca gagcgtaggc gagttcctcg acggccgagg gaatggtttc
     7141 aggtgtgaga tgtgggagac tggcgaagaa accgaaccga gtggggtttt cctggtgaag
     7201 ttggaagccg tagaggttga tttgccgggc gaggttggcg gattccactg gggaattgga
     7261 catgatagag gtgcccggtg cagttagaga tagaatggcc gtacgggtgg agtgggaggc
     7321 catgagggag agggtcgatt cgggggtcca tttggggagg tgccagccag aggggtcacc
     7381 aggggtcgag ttgaaagcta ctttttaatt aattgtcttt ctggagagaa gtcagggttc
     7441 atgtcagcat acccttgaca taggcagggg ggatgaagtg gtggtgcacg tcgatgcggt
     7501 tcatggtgat gagtagatag atgagtctac tactggaatt atgtgtattt ttatagacaa
     7561 ataaatggga atgactggta acatatatat tgatcataag gtcataaggt gtaaacgatg
     7621 catccgggcg gccgagtaag aacaaggccg atcatactcg gccggaggac atacaggtag
     7681 agcaagacca ggcggtttag cgcagaatgc ctatctggcc agtgtgacta gcacttcaca
     7741 ttccggggct caattggata ctcttctggt cttgagctcc atcctctaat gcagctccat
     7801 cttcatattg gccagggaaa tatcatatac ccgcaccacg aacagctcca gcaaagagac
     7861 acccgtcaga tacaatccca gcttgatgtt cgacttgaaa attcgacctc ccgagtgtcg
     7921 atcctttaga tccaacgaca ggatatgcca cggcacgttc accatccaca cgccgagtcc
     7981 cagcacccag aaaatgagcg acatatccgc ccgcagtgcg gtgacagcaa agagcaatac
     8041 ctgtagggcc cccagcacag ccagtaggat ctggacattc ttccccaaca gcacggcgag
     8101 tgacttgacg ccaatctttt cgtcatctgg acgatcctgc gtcgcataga agacatcaaa
     8161 gtagacaacc catgaggctg tggcgaagaa tagagggagt gcctgatcca gatccttcag
     8221 atccccagta attcccaccc atccggggaa caccgcgcca ccgatgatcg cccctagaac
     8281 gacttggggg aatggcataa tgcgcttcat gaatgggtag atggtgctca gtacccatac
     8341 aggaatgaag cccgccatga cagccgggcc tagcgttccc caagtaatgg cgagtgtgac
     8401 aggcaaccag cagataaagg ctacgacggc ctcagaggtg ctgatcatcc cagatggtag
     8461 agggcgaatt ttgcatcgct cgacgtgttt gtcgagcttt tggtcacaga tatcgctaat
     8521 gcacttttca gtgggagata tacatactca tttatcttcc acacttactt gaatgtacag
     8581 aatgcacagt gtgtagctgt cacgctggcc cagatgccga agagtaaacg aaggaatggc
     8641 gcgagttcca acgacacatc tcgcatgcct gcggccacac atgcgcccca gatggcggga
     8701 taccagcata gccaggcttc acgagtgtgt aaccgggcga gttcccatac accgcgagcc
     8761 acattgcgct gggatttggg ggtagtagag actgtcatat tgatgatgct attcggagtg
     8821 cctcgatgaa agcagtaaat cgaaagatcc ttatagaaga tagattaaga tgaaaagaga
     8881 ccctgtgaaa agattacatt tcaatgcgta cctctctgta tcagccgggg ttctcggggt
     8941 cggtcttgtt gggccgagtc gtgtcaggcc tcgcgttagg gcagagaaat ctcatctcgg
     9001 ccgatcgctg accatccgag tctatgctat atcgctagag cgtcagaccg gccgatagtg
     9061 gccctgtgaa ttagatggga aactgaaata gactactatt ggtatcaggc gaagtataga
     9121 agtatcgaaa tagcgaggtc gtagaatcta catattaata tatagagagc gagctctatt
     9181 tgttcggatt cactgcgcga gagattaaaa tcttcaaact tgtttagtta ttcttcgtca
     9241 tagagtctac attacacatc ataatgatta cttcaacaag cagcacagag gttctcaccc
     9301 ccgccaatgg ctccgacgat agcaaaggca caacgactcc ggcaaccagc tccggggacc
     9361 ctgaaatgca tgatgaccta ctccgaaatg atacccacga cgacgttgct ataatcggca
     9421 tggcatgtcg cgtcccaggg gacgtaaatt ccccctccgc gctgtggcaa ttcctacttg
     9481 agaaaggtga cgcttcaggg gatatgccca cttggcgttg ggatccctat cgacagcgcc
     9541 atcctcgtaa tgcggccgta ttggctgaaa ccaccgccaa gggctacttc ctcaatgaca
     9601 tcgaccagtt cgatgctgca tttttcgcca tctctccacg cgaggcggag caaatggatc
     9661 cccagcagcg aattgccctc gaggttgcct gggaggcctt ggagaatgca ggcatctctc
     9721 cttcccgtct tgcgggttca aacacttccg tatacatggg tgtcaactcc gatgactatg
     9781 ccaagctggt cttggaagac cttcccgatg tcggtgccca catgggcgtt ggcacagcct
     9841 actgcggcat ccccagccgt atatcctatc tgcttgattt gatgggtccc agcgttgcaa
     9901 tggacgcggc ctgtgcatcg tccctggtcg ctgtacacca tgcccgtcag gctatccgtg
     9961 ctggggagac tgacttagct atcgcaggtg gtgtcaacgc actcctggga ccaggtttga
    10021 cccgggtgct ggacgaagct ggggctatct ccgccgatgg aaagtgccgt tccttcgatg
    10081 actccgctag cgggtatggt agaggcgaag gagcgggtgt ggtcatctta aagcgtctgg
    10141 ataaagcctt gacggacggt gaccaagtgc tagccgtact caagggcagt gccgtggcct
    10201 cagatggcaa gacacttggc atcatggccc ccaatgcgca ggcacagctt ctcgttgccc
    10261 aaaaggcgct gaaagaggca aaagtgacgt ctgactccat caattatatc gaggcccatg
    10321 ccacctccac atcactgggc gatcctacag aaacgaatgc cctagctgag gtatacggtg
    10381 tgggatccgg acggcatcca tctgacccgt gctatattgg ttccatcaaa ccgaacatcg
    10441 gccatctgga agctggtgcg ggtgtcatgg gtctcataaa ggcggtactt gtgcttcgct
    10501 atggggaggt gcctccacag gcgaatctgc agacgctgaa tagcaaaatc gcatggaagg
    10561 agaacttgct gcgcccggcc cgcgagctgg tgacgctacc ccgtggcgcc ctatcacgac
    10621 cgttacgggc agctatagca tcgtacggat acagcggcac agtgtcgcat gcgatcatcg
    10681 aagcatttgc aggacaatcc ttgtttgccg agcgactggc ccaaatcccg gacagtgatg
    10741 ctgcgccggc cctccttctc ttgtccgtgc ctcaagcgaa ccgaatctcc acaacagctg
    10801 ctggtctaag ccggtggctg cgcgacatgg atggagcggt atccctggcg acagtcgcct
    10861 ccacgctatc gcagcgccgc atgcatcacc gcttccgcca cgccattgtc gctgattccg
    10921 tcgcaaacgc catcgctacc ctcgatgatc tggcgaaaga tgtgccaagt cggtgggcga
    10981 tcagtgaccg aatcggatcc gaggcaggga agggcgcggt ctgggtgttt tcaggccatg
    11041 gtgcgcagtg gcctgacatg ggtcgcgaat tattccactc tagcccggcc ttcggagaag
    11101 tggtgcgaaa cctggaacca atcattcaag ccgagttagg attctccgcg attgaaaccc
    11161 tgcacgccgg ttgtccagat cgcaccgatc ttatccaggc gatgacattc ctcatgcatt
    11221 tgggcattgc cgccgtgctc gaggcggagt ccggtcctcc aaccgctgtc gtaggccatt
    11281 ccttgggcga ggccgctgcg gccgtcgtct ctggggctct gacctggcat gaagcagcct
    11341 tggtagtatg tcgacgagcg cgtctttacc gcgagttcat gggacaaggt gccatggccc
    11401 tggttcggct gtcggcatcg gaggcccgtg cccgcattgc cacgcacccc ggcgcgtccg
    11461 tcgcaattga gacgtcgccg accgcgtgtg tggtatccgg cactgttgac gcgctccaga
    11521 gattatctga gcaatggctt gaagaaggtg ttgaggtgcg tgctgtggcc acagacgtgc
    11581 ccttccatac accactgctg gagaagctgg ctggtcccct ccgcggagcg ctgaagaacg
    11641 agctccatcc tcaagtgccg catcgggctc tctattcgac ttcactatta gatccgcggt
    11701 cagacctatt gcgcgatgcg gaatactggg tgatgaatat gattcaaccg gtgctattgc
    11761 agtcaacagt ggcggcactt gtggatgatg gattccgcgc atttgtggag gtggcgagtc
    11821 atcccatcat aacgcactcg atcgttgaga ctatcagcga gcagacgacg gaccgtttta
    11881 tcgcgacacc cactatggtg cgcaagcagc cagcactaaa gagcatcttg gccgctgtgg
    11941 gccgcctgca ttgcttcggc tgcgctgtga aacccacaga cctcgacccg actgtgccat
    12001 ggagttcatc agtacccggt accatttggc atcaccagtc attctatcgc gctgtgagtg
    12061 ggatgacggc tgcacaactg gcatcgaccc acaagcctgc cgccaatgac ctgctcggta
    12121 ctcggaccgc cctgtgggga acggaggagg tactttacca aacccgtctt gaggaagaca
    12181 accgaccttt ccccggccgt cacccactgc atgggtcaga gattgtgcct gctgcggtgc
    12241 tcttgcgcac attcctgcgt gcgctgtctc ccaggagcgt ggaggaagtg tcgctccagg
    12301 ttcctgttgt tgtgtctccg gcccgcgaga tccagatccg gcataacacg cgtaacatca
    12361 ctatcacatc tcgtctggag gagtcgacaa gcaatgaaca taactcgtgg cttgtcaata
    12421 ccacggcgac cgtgggggct gatgcaacac cctccgttag ccatgtcgac atagcggagg
    12481 tcgcgaaaag actgccacag aagttgtcag atagtttctc gattgactac ctcgcctctg
    12541 taggcgtgtc tgccatggga ttcccatggc gggtagccca ccatgtggcg agcgacaacg
    12601 agatgctggc cagggtacat gccaacccag acagcctgcc cggcatggac gatcttttga
    12661 cgtctgtcat ggatgctgca acttccattg cgtcaacgct ctggcactcc aagccccgac
    12721 tccgtatgcc cacagccgtc cgtcgtgtcg tggccgttgg cgtggccact ccgcaagtcg
    12781 tgtacatcca ctgcaccaag gcacaatcct ctgtcgacga agccgacgtg atcattagca
    12841 gcgaggaggg catggtgctg atggagatcc agggtatggc atttgccggt gttgagggtg
    12901 agtcgctgtc acgcaaaagt acctctggtc tagtacacca aatcagctgg ccgcctgccg
    12961 cgctggctga ggagcctctg gagttcgccc acattgcatt cctgacagcg gatgccacca
    13021 aggctcaggt gggaacatac cagagacaga ttgagggaag aggcatctcc acctctatcc
    13081 atgagcgtgc ctccgacttg ccgttgacaa cccattcgtc tatggcggtc gtttacctcc
    13141 ctcaattcac cgatcggatc tttgacaccg cgacccgcag ctgcaatgac ctcgtgacag
    13201 cagcccaggt tatcctatcc tcctcggata agcccaccat ccgcctcttt gccgtcacct
    13261 ctgagtccaa tctaggccac agtgccctca caggcctcgg tcggatcctg cacactgaac
    13321 accccgagat ctggggtagt ctcatcgacc tcgaagaccc ctcggtcttc ccgctcatgg
    13381 caatgcgcta cgtgcgtaac gctgatgtca tcaagatcga ggatggggtc ccgcgcaccg
    13441 ctcgtctccg ccctctccgc cccgctccgc cccactcaac cgctggaccc gctactctca
    13501 cattttcccc ggcatctact tatctaatca ccggcggact cggctctctc ggaatctctg
    13561 tagcccagtg gatggtcacg caaggtgcca gacgcattct actgctctct cgtcgctccc
    13621 taccgccgcg ctcgatctgg acggcatcgc ataaacctgg gactcagttc atcatcgata
    13681 gtatcctctc tcttgaacgc cttggtgcca ctattcaccc cgtagcaatc gacatttccc
    13741 acccatccgc agtgaccaac cttcgatcag ccctcaccac actcagcctc ccacctgtcg
    13801 ccggcgtagt tcacgccgct ggcatcctcc gcgaccaact catcgagcag atcactccag
    13861 atgcctttga agccgtcctt gcgccaaaga ttgcaggtgc cttggcactg cacaccgtct
    13921 tccctcccag ctcgcctgac ctagacttct tcgtcctctt ctcttcttgc ggtcagctcc
    13981 taggattccc aggtcaggcg tcgtacgcga gtgggaattc atttttggat gccttggcac
    14041 gttcacgcag aaaggagggc gataatgcca tctctctcct ttggacatct tggcgtggca
    14101 tgggtatggg ggctagttcc aatggagccc tggaggcgga actgtatgct cgtggaatta
    14161 cggatgtgac tcctgacgaa gctttcctgg cgtggagttc tatctctggc acggagggtg
    14221 ctgatcatgg tgtcgtactt cgtgctcgac cgcttgaatc tggggagccg ctgccacatg
    14281 cgatcctgag ggatattgca ccgaggaaag agaaagctgt cggtgaaggc aatggggaga
    14341 atgaagagca gaggaagaag ttgagtggca aagaattggc ggagtatgtg ctagtcgttg
    14401 tgaaaaagtg tgtgtccacg acattatcta tccctgagga tgaggtagac gagacagtgg
    14461 cgttgccgga aatgggcatg gactcggtca tgacggtgaa tttccgcatg agcctacagc
    14521 agacgctgac ggtgagtgtt ggaccaactt tggtgtggaa gtacccgacg gtgcatcatc
    14581 tggtggagta cttctgccag gtgttggatg aatagatcag aaactgcaca gtcgaatata
    14641 tgatatatgt atgtagttgt atttactttc ttgcaagatc gaactactaa atagtatgtt
    14701 tcgtcaagtt tatataagaa caggcgattt cataagcatg tctacagctg taggaagtag
    14761 tatctctatc gacagaaaca cagcatacag acaacttctc aaacaacttc tcaaccccct
    14821 aatcctcccg ccgctttgtc aacgccataa actctccatg aaactggggt actaccatat
    14881 catcccattt catgtcctcc tcggttgtcc ctacgaggtc caagtcgaat cgtcgcacga
    14941 tatacgcaat ggccatatac atctccatat acgccagact acattgcaga tccgttagta
    15001 aaatatcttt ctcagagacg agcacatact tgatccccag acaagatcga ctccctcgcg
    15061 aaaatggcac caggaacttg gctctctctg cagtcacctc ggggccctgc aaccaacgct
    15121 ctggatcaaa cacgcgagga ctttcgaata gcgtctcgtt gtagtggata tggtaaattg
    15181 ccattcccac ccgggttccc gcagggatga atcggccgtc cggaaggcgg acgccacccg
    15241 ggggaacgag acggggagtg cgggaggccg cgggagagga gtatctaagg ccttctttga
    15301 tcactgcggt ctgttttgta ttatatcaat gtcagatatt gtgcttgaca ggacgtgctc
    15361 tcttccgagt gaggaagcga tagaaactac gaaccagata tggcagcgcc tcgagctgaa
    15421 gatacgagac atgggaatta ggcgttggca taacagtttt caactccgcc aggaggcgat
    15481 catggacttc acggttattg aagatattga aaagggtgac tgtgttggca atcccggtgg
    15541 tatcgtcccc tgcggagatc acggtaagaa gctcatcacg gagaccctgc ttgtcgggga
    15601 ctgcgtagcc cttttcggga atcggaatga gcaaacgctc catgagagtt ggaaaggtag
    15661 gggtttttcc cgccgcggcc gcggccatat actcatcgat gcggcgagcg gcgaactgga
    15721 tagaacgagt gagtacatag tgtttcgctg ggcaaatata taggtcgagc tcacctgttc
    15781 caactcatgc cccatctcaa cagaatgtga aatccgtttt gcaatccaca gggggagcga
    15841 attgagcagt ctcacaaagg ggaaagcctt gataacatgt agactgggca ggtattgctg
    15901 gaagacgcgc acagggagcg acttgaactc tggatcggcg agggcattga gggattgacc
    15961 gaatgcaaac tgagagacca tatctggatc attctattag atcacggatg cgatggaatg
    16021 aagtaggata tagtgcaaga aggaagttac atacccatcg ctagagactt caaagcccac
    16081 tccattgaga caggttttcc ctgggcaaaa agctcatcaa atcgttgcga gcagcgatca
    16141 acatgctcca tcagcattgg ctccaaactg aggatgttct tcttggagaa cagtggctct
    16201 agtggtgctt ttcgctgctt gtgccgcacc gggtcactct cggccagcgt gcttgacggc
    16261 gctcccagga ccttgtgcat cgatgggtct ttgtagtacc gactacccgg ccggtatagc
    16321 tcatgataaa aggctggatc atatatatgc acctcattgg gacccatgcg caacgcaggt
    16381 cctaggcgtt tatgcatctc ctcgagcttg aacagcatct ggcctttacg gccgggtttg
    16441 acaccgatat tccaataagc ctcccaactg cggtatgtgg ttagcaaggt aggctcagaa
    16501 acaacagaga aatacacact attcccctaa agccgcccat ggtgagcctg ggaaaacggc
    16561 cagtggactg aagaagatca ggtagacagc acgaatggca tgatagacag caaaggtgcc
    16621 cgccgcaatg agccagaggc tcacaggaag cacagaaagc aaagccattg gtttataatt
    16681 gaccagaaat gatatcaaac tctggccatg tccattttct gtttctgtca agttatattt
    16741 aactgcgttg cttatgtcgc gatcggccga ataccacgca gcccggatga ccgaccatgc
    16801 cgagatagaa aagtcacata ggtacgacca agaccggata gaagatactc tcttctcctc
    16861 caatatcttc ttgccatggc tgaaatggat gtttcctcgt ggaaacccac gaagttggaa
    16921 acgaagccgt tctccctcga cagcggacac tatacagccc tagccttcgt cctcgctgtc
    16981 tgcgtcccac aggcccccca tggaactgca cttcgctatg gactacttct tctccaaatt
    17041 acttgcggag tacaggcatt ccttgcccag ccaccttcag taccagaccg ggccgtcctc
    17101 tacacgtcgg gtgtgcttat gggcaatctg gtagcgcgct actttgaccg attgtacacg
    17161 accgtcccag agaaaacatt ccaccgcatc atcgactccc aaactcctga ggatacaacc
    17221 cagctttccg cacctaagcg ctttttctgg gccctggaac tcttcagcgt cacccgcggt
    17281 atcggctgga actggcgcgt cgccggcatt cccaaatccc cggtgccaat caccagattc
    17341 caattcgctg cagcccagct cctcagatgg actgttatgt acgctggtct acatctcgtt
    17401 aacgtgacct gtcaggtcgt ctcgtcaaac ccaaacgcca tcccttcact tccgggcaat
    17461 ttgcacatct acgccctgat tgtgtgcggc tttgccatca caatatacag ccatttcgct
    17521 attctaatgc tcccgctttc ggctctctgt gtcggtctcc aagtcggccc tcgctcgtgg
    17581 caagctgttg cctcctggcc accaaatttc ggtagtgttc gcgaagcata cagcattcgc
    17641 cgattctggg ggtacacttg gcaccagcag ctacgacgac aggctggtgc gcctggtgca
    17701 tatcttatta gcttgttgcc ggacagtgtc atgacgtcta aacggacggc tgttaaactg
    17761 gcgagacggt actcactcct catgatgagt tttgtcatct cagggttaat tcatgcgtgt
    17821 ggaacctacc aagtgacacg agcgcttggc ctgcctttgt cggacggcgg ggagatgaag
    17881 tattttgcgt tacaggggat ggcaatcata gccgaggatt tcggttgttg ggtattgggt
    17941 attgatgatc ggggaacaca gcctggggtg atgcggcgat ggatgggata tgcaatcacg
    18001 ttatcttggt atatctggag tcgcgtgcag ctgaaaggtg tgccggtagc tctggcgatg
    18061 gggattgaag atgagagggg ggacttgttt gctgcattgg agctggttcg ggtgtctgct
    18121 gtagcagtgc cgggcaattt tgtggcgatg gcctgggagc tgatttggtg agggttatta
    18181 cgaagctgct acgagaagcg tagaagccag tggacgagat atctcttttg tatatagctt
    18241 tgaattagtt aggattgatt cgcgctagat taaggaagcc tcggtggctt ccacatggat
    18301 gaggtacaca ttgatcacaa cttaggaaca caaaaatcac tctccggatg ttctatttga
    18361 gctcggcagg aagggtggtc aatgtgccga tctcgttaat tgtctcctcc cacaatttct
    18421 tctgaatctc ctggcccgcc ggtgatttga tgaacgccga tttactatag gggaagatgt
    18481 gttagctgtt tgcaatagac cactttctac ggaaaaggcg tatcacttac tcagagatgg
    18541 tcttgtcatt caagaacttg ccatgagact cagggcctac caccagcgca ctgttcagga
    18601 tgatccagcc acccacctca acaggcctgg cgcggaatga tttgacaacg ttcacaatca
    18661 agcgcaggtg catggggaga acatcgctca tgttggtgtt caccatgccc ggacacatca
    18721 tgttgatgat gactttcttg ggatccagtc gcggcgccag attgtacatg aacatcacgc
    18781 aaagtagctt cgagtcccca tagcgctgga acgggacaaa ggcttcttct ttgtccatat
    18841 gcgcaagaac accttcacca ggcttgatag gagctttctt ctccaagctg gtgacctcgt
    18901 gtgcgcgact tccaacccag ctaatgcgtg ccggagagcc ggtcttctct gcgcctgctt
    18961 ggagatacgg caggagctcg gcgatcaaca aaacattgga gtagtaattg acttgagtag
    19021 ttcggtcatg accgcttgcg ctgcgttcca gcttgagcag accgataccc gcattgagaa
    19081 tgaggatatg gacgaccgga atctcttcgc ggagctgctt cgagaaccgt tgtacactgt
    19141 gataatcgtc cacatcaagt tccatgacct tgatggtcgg cttggggtta tgggtctgaa
    19201 tgcgacggtc ctggcggagg gaagttgcgc aggcctcgcc tttggcgaca ttgcgcacgg
    19261 caagaatcac ggtcgaggcg cgcagtcgca ggagctgttt ggtggcttcc agacccattc
    19321 cggcgctggc accggtgatg acgacagttt tacccgtcag gccaatgccc gtaggtaggg
    19381 gatcgacttt cggctggatg atgttgacca tgatgagaga tgaatcagga gttgagatgc
    19441 gagaattgag gcttccaacg tgaagagcac agttgatgat tgaagagaag aagagacatc
    19501 ggggtagtca tactcaagat accctttcct atcacaaccc tgctatcggc catggaggtc
    19561 ctttgttgga ttgttcagcg gagctgacaa acggcgcatt ccttgatggg gtgactcagc
    19621 attcggccga cgccagccct aaaagggaag ttccaaagga cgaagaccga gacaacctcg
    19681 cccgaatgaa cacggccaaa tgtctatctc gtatgacatc cagacgagat ggaattctcc
    19741 ggtatgttat cctgggaggt aatcgagaga cgagaaggaa catcgagtat gtaaagtaag
    19801 cagttgatcc atttcgttcc ctcctctctc tggtctactt ccagttctaa ctagaaatgg
    19861 ctccctgcaa acctcgtacc tttacagccg gtcaagatcc gctgacaaaa tttgatggag
    19921 ccatctcggt ccgtaatctg ccccggcccc cggaccgctt gttcctgttt cacggtatca
    19981 tgaggccaag tcgcggcatc tatgccaagc tgatcgccac cggccaaaag ccccccaccc
    20041 atttccaccc ctcccagtgg gaattcttcc gcgttcttcg cgggaacctt actatcgatt
    20101 tcaatgggcg tgccattcat cggaccgcga gtgatggtga actggcagtg cctccctata
    20161 cccatcatgt catttatgga accccgggga cggagatgaa tgaggtcgaa tttgtcgtga
    20221 gtgccagtga tcctgctgcg gaagagcagg gtgccacggt tatggaccaa ccgttctttg
    20281 agaattggta tgggtatcaa gaggatgttt ttcagcgggg ggagaaattg gacttcatac
    20341 aggtgctttc ggtgagcaaa gtaatttccc ctgaaaaaat atcccaaggt taaccaggta
    20401 tagatgtttg atgccggagg cacgtatcta tcgccgccgt ggtgggtccc cttccgctcc
    20461 tgggttgggc tgtttctcgg gatcgtggtg ggccggtgga taggcgggct gctaggctat
    20521 gcgccttttt atcctgagtg gacaaccgac tgggaggcag cctgcgagac aatgcagcag
    20581 agctggttcc aacgtagatt tgcggatcca caggcacagg aaagagcacg ggaaaagttt
    20641 cgtggtcagt tggagcagga ggcatctgcc aaagggggga agtcggagta gatagatatt
    20701 tttggagcag gaaactgtat atattcacat atctagatag acagacactc ctccacggat
    20761 tgactggaat ctatacatag gaatacgtgg ctattggaca gatggatatt tccatactcg
    20821 tacttaatct caatttccgg gcatagatga tgctttcacc atcaccatct tatgaccgtg
    20881 tacccatatc agcgagcctt ctgtgccttg gtgttgacca gggagtccag ctgcttctcg
    20941 attctctgaa catagacata gaccgcagca tacaccatgt cagatccaat actacccagc
    21001 agcaaaaact tcccgtaagg ggtccacgca tatccgaatc tctctggcca atagtgtata
    21061 cgccagaaga agcaacacgc agcggcgata gtacccaaca ttcttgtcca ccttctcata
    21121 gtgtcagcgc cagatcaaga tgactatacc tgagactatc cactcaccaa attccccaag
    21181 agtgaccaag ggtatttccg cgcgagagta gctgggcaat cgagctgaaa ttgataagga
    21241 cctgcatagg ccatgccgtc atgaacacga cctgtcgccc aatgctcggg ataaatgtgg
    21301 ccgcgatcgc caagtgcagc cacagacaga tcacacatcc gaccacgatt atacccgcga
    21361 gatgctgcgc caccaatggg gactgcttcc aggcatacgg ggccgatcga agaattgcgt
    21421 agaaaaggac cacatcgaca atcatccatt gcgcgaacac aacctggttt agcagccctg
    21481 ggccgtagac aaacccgtag actgcttccc aggtaatgtt caagcagaga caatggagag
    21541 gcattgcgta ggaacgatct ttgaaagcct ttttggccat caagatgtac gagatagacc
    21601 agaggattcc tgatatggca gtgaacccat cgggtacaga cttcacatgc cagtagggcg
    21661 ccggggtatt ctcgtagtca cgattggcgg ctgcccactc ctcgagcgcg aagaagcaca
    21721 ttttattcag attgcttaat ggcgaaatgg gaaagagata atttggcgct gtctgtacct
    21781 ggatctccat acatcgttgc tctcatataa agcgagaggg atcctgatcc gtcggccgag
    21841 ccagatcggt agtccgagag ccgcatcgct agtcaggcac gacaacatcg atcgttctat
    21901 ctttcaactc gggtttaaat gaaagaagga ggaaaatacc tgtctgcctt gccatcagct
    21961 cgaaatcata ccattcatgc gatgtcccgc ccgagatggc aggtggtaga tccataaagg
    22021 gctggcaacg cgcacaaact acaatcaaat caaatcactc aacatgacca agatgacctc
    22081 gataataggg atccttatgg gtgttctgac cacagccacc gcggcctcca tcccaacagg
    22141 atcctctgct gctgctgctg ctgctctcgg ctcgctgggc gtttctcccc catctggcaa
    22201 cgtcctcatc ggaaatgccg gctacacctg tagtctcttg aatcgggtct tatccaagaa
    22261 cgagacattt acagtgacct cgccctatta cgatgttttg atcgacgaag cctggtcgga
    22321 gaattgccga ttgaatgcgt cttgcatagt cacgcctgaa tctgccgaag aggtctcgcg
    22381 tctgttgcag atacttagta ttctggaaac aagatttgcc attcgctccg gtggacacaa
    22441 taccaacccg ggattcagtt caatcggcag cgacggggtg ttgatcgctc tggagaagtt
    22501 ggatagcatt tccttaagcg ctgatcgcgg aactgtcact gtcgggcccg gtaataaatg
    22561 ggagtctgta tacaagtacc tccagccgta taatctcacg gccttgggcg gtcgcgaagc
    22621 ggttgtgggt gttggtggat acattcttgg tggtgagtga aaagttcgtg ggaattctag
    22681 atgaaccaag acattgacag aaacaggcgg tctcagcacc ttctacaaca cccacggctt
    22741 ggccattgac agtgtcaccc gattccaggt ggttctaccc aatggaacta ttgtcgatgc
    22801 caccccaact gagcatgccg atctatataa aggcctgaag ggaggtctga ataacttcgg
    22861 tgagactgct actgtctatc aaatcacctt tcaaccacct aacaggagaa ggcatcgtaa
    22921 ctgaatatga cctcaccacc aataccggcg tcgatatcta ctatgagata aaaacgtaca
    22981 ccactgccaa cactccggcc gtgcttgcgg cctatgcgac gtatcttttg gacgccgaca
    23041 tcaacagcaa tgtggagatc cagatcaacc ccagctacac tttggtcttc tacgggtatc
    23101 tcggtcatgt atctgcacct acagactttg atccattctc cgacataccc gtggcctcca
    23161 ccatgtaccc accgacgaac ggctcgctca ctgagcttct cctcagcatt ggctccaccg
    23221 gactgacatc cgagggtgtc tcctatagcg gtaccttttc attcaaggtg acagggtcta
    23281 cattcttaca ggatacttat tcaacctatc tcgaggccgc cgcctctctc ccgacgggcg
    23341 cggtactctc ttacgtgcct cagggcgtga ttccgaacct agtaactcaa ggaaagtcgc
    23401 agaacggagg gaacctactg ggtctggatg ccacgcctca agtctgtatg tatccgcttt
    23461 tactcatctc cacccgggaa acgcctctaa ccaaagtctt gtacaggggc gaatatcttc
    23521 gttcaattcc cagctacact cagccaatca gaggtggcag gttctgtaga ctcattgctg
    23581 gccaatctca tctccagcgc aaagtcggag gatcttttcc tcccctatat cttcgtcaat
    23641 gacgcgggtg ccaagcagaa gccgctgcag tcgtttggag aaaagaatat caagtatatt
    23701 gacacggtcg cgaaaaggta tgaccctaag agaatcatgc agaggctgca gaaccaggca
    23761 tactttgtct tggaggagtt gtaaaatacc tcatcattgt atatatattt ttggttctgc
    23821 gtcggacact ggaatcgaag tcacgttacc gcaacggtgg acttgtagta gtcagttaaa
    23881 tcctcttcct ctctctcctc ctttcctctc caagtccatc aatccagttc caatacagtc
    23941 ggatttcatc tctttgcgtc tttctctgac ctctctctga cctctctctc acctctctca
    24001 cctctctcac ctctctctca cctctctctc ccattgctct cttctctttc tcagcttgtg
    24061 tttgcctttg gtccttgtga ccaaccacag gttccaaaat ggagaaagct acggaagaac
    24121 ccacgaacgg tctccctcgt ctcaccatcg acgagatgct taagcgctac ccgcggtatg
    24181 aagttgaaaa agccatttat cgaatcgatt atccgaggta cggaacagtc tatccggttt
    24241 tacaattata aaactaacca tctagtagtc gaccggccaa ggtaacccgg cagtttgagc
    24301 agcagatcga ccaagacgta aacgtggaaa gttgccgtga aggcatacag tgggccctcg
    24361 aaaagatgcc accaacccgc ccgtaaggaa gcctgc
//
