LOCUS       BGC0002626              5986 bp    DNA     linear   ENV 23-JUN-2021
DEFINITION  MAG: Nostoc sp. TH1S01 contig-206-p2, whole genome shotgun sequence.
ACCESSION   BGC0002626
VERSION     BGC0002626
KEYWORDS    .
SOURCE      Nostoc sp. TH1S01 (soil metagenome)
  ORGANISM  Nostoc sp. TH1S01
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:06:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5986
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..174
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KAF91_23765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="MBU7585862.1"
                     /sec_met_domain="mvd (E-value: 2.1e-07, bitscore: 20.3,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHLIADIYLIAPEIYLTKNTISTNTIKSVDVRMVKFFARFLEE
                     QTIEGTQTPSWL"
     protocluster    1..5986
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[0:898]"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
     cand_cluster    1..5986
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(mvd or mvnA)"
                     /kind="single"
                     /product="microviridin"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..5986
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002626"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..5986
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="microviridin"
                     /region_number="1"
                     /rules="(mvd or mvnA)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..174
                     /locus_tag="KAF91_23765"
     gene            298..438
                     /locus_tag="KAF91_23770"
     CDS             298..438
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308507.1"
                     /locus_tag="KAF91_23770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="MBU7585863.1"
                     /sec_met_domain="mvnA (E-value: 1.4e-22, bitscore: 68.7,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 6.6e-11, bitscore: 31.6,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTNTVKPANVEAVPFFARFLEEQVTEVSDTSPRNTLKYPSDWEE
                     Y"
     gene            528..668
                     /locus_tag="KAF91_23775"
     CDS             528..668
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308507.1"
                     /locus_tag="KAF91_23775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="MBU7585864.1"
                     /sec_met_domain="mvnA (E-value: 1.1e-21, bitscore: 65.8,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 3e-11, bitscore: 32.6,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTNTTKAANIEAAPFFARFLEEQVAEVSDTAPYETKKWPSDWEE
                     Y"
     gene            758..898
                     /locus_tag="KAF91_23780"
     CDS             758..898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308507.1"
                     /locus_tag="KAF91_23780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="MBU7585865.1"
                     /sec_met_domain="mvnA (E-value: 4.9e-21, bitscore: 63.7,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 6e-12, bitscore: 34.9,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTNTTKAANVEAVPFFARFLEEQVAEVSDTAPYESRKYPSDWEE
                     Y"
     gene            1087..2076
                     /locus_tag="KAF91_23785"
     CDS             1087..2076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408791.1"
                     /locus_tag="KAF91_23785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MvdC family ATP-grasp ribosomal peptide maturase"
                     /protein_id="MBU7585866.1"
                     /transl_table=11
                     /translation="MHLSRDVVLLISHSGDFFTIDRVAEALSKKGAQPFRLDTDKFPLE
                     VQLAAHFDKSKSYHTIEYNNQSISTEQVQAVWMRRIWEPQLGKELAPKFREACIKESKA
                     TLNGFWDSLKGATWVDNLERIDYAGSKLRQLRVASEVGFTIPQTLVTNKAEAAREFFKQ
                     VNGKMVSKLLTTLSYSMEANSSFFLYTSTVKEEDLQDAESLRYCPMVFQEQIPKQQELR
                     VAYVNGNVFVGALNADVYATAKADWRKPGVEVGAWQHHQVPDEFVRRLQAFMGKFGLLF
                     GSLDFILTPSGEYVFLENNPVGEWGMLEKDLDLPISDAIADALLQTNN"
     gene            2134..3111
                     /locus_tag="KAF91_23790"
     CDS             2134..3111
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006196351.1"
                     /locus_tag="KAF91_23790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MvdD family ATP-grasp ribosomal peptide maturase"
                     /protein_id="MBU7585867.1"
                     /transl_table=11
                     /translation="MTVLIVTFSKDNESIPLVIKEIEARGEKAFRFDTDRYPTEVKLDI
                     YCGDTERVIITDGEQKLDLSEVSSVWYRRMRYGQKLPDSMDKQYRDASIQECRVSVRGM
                     IASLPGFHFDKMANVDRANNKQLQLKVAKEVGLLTPRTLTSNNPEAVKQFAQECEQGII
                     TKMLSSFAIYDEQGRENVVFTTPITEDDLENMEGLRFCPMTFQENVPKALELRTTIVGH
                     RVFTAAVNSQSLEGSTYDWRKEGKALVKNWKPYELPEDIEKKLLKLMAEFGLNYGAIDI
                     IVTPDGRHVFLEVNPVGEFFWMEIYSPHYPISQAIAEVLLTKKN"
     gene            3404..5434
                     /locus_tag="KAF91_23795"
     CDS             3404..5434
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 114.4; E-value:
                     1.2e-34)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408795.1"
                     /locus_tag="KAF91_23795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="MBU7585868.1"
                     /transl_table=11
                     /translation="MQTPSVREQTTTNPFSAITQFWEDVKVVAQPYWYPTKAEGRAFSD
                     VIRSWGALILLILLILGFVGIDAANSYWNRYVTDIIIEERNLDKYYSTLWLSNIILVVS
                     VIIVTFLRYVKKKIILDWYKWLNNHILKIYLSHQAYYKINFKSDVDNPDQRLSQEIEPI
                     ISNALNFSTTFLEKVLVMGSSIIILSTISVEIAVYLVIYTIVGNLIAVYLNQYLNKINQ
                     EELAFKADFAYCLTHVRNHAESIAFFQGEQEELNIIERRFNNVLKTAEHRMNWERGQDA
                     FGRAYQSAIGVFSAYILTPLFLQDQIDYGEINQISITCFMFSTALGELIAQFGVSGRFS
                     SYVQRLAQFLDALQAVSKQPENVSTIKVLEEKRLAFENVTLQTPNYEQTIVEDLSVAVG
                     PGEGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLVRPPLKEVLFLPQRPYIILGTLREQL
                     LYPHTDKKMSDKELEQILRQVNLQNLLARVNGFDTEVPWENILSLGEQQRLAFARLLIT
                     HPSFTILDEATSALDLNNEGNLYQQLQETKTTFISVGHRESLFNYHQWVLELSQESSWK
                     LVSIDEYRQQKAIAIKPIEKEQITIEILPDHKLTIEPTNSALTTIVGLSHKELQALTDY
                     SLATIRTKASQRKPVTTKDNVTYRYNKDPKVLKWISDSSTQ"
     gene            5456..5986
                     /locus_tag="KAF91_23800"
     CDS             5456..5986
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 84;
                     E-value: 1.9e-25)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.1"
                     /locus_tag="KAF91_23800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="MBU7585869.1"
                     /transl_table=11
                     /translation="MEKLVTTRLNLVPFTLEVVKVAIMGNDKLASFLGVKVLPDWQSEE
                     FREILPEIADILCKYQFQHEWGWGSLIIHKAENMLIGYVMVKVIPDSSFSPTGSLEIGY
                     YVARSYRLQGYASEATKAVIDWALAQPSVQSVTAGCNPDNIASKRVLEKIGMQLIESRE
                     KVLVWKLGKTATV"
ORIGIN
        1 ttgaccacac atttgattgc tgatatatat ttaattgccc cagaaattta cttaacgaaa
       61 aacaccatat ctacaaacac aatcaaaagt gtggatgtac gaatggtaaa gttttttgcg
      121 cgtttcttgg aagaacaaac tattgaagga acacaaactc cttcttggct ttgaactttc
      181 gagtttccga tagatgcgga agacaagtaa ctctagtctt ttcatcggaa attaaggcag
      241 tagaagttat tcaataacta ctactcttgg gtaacaacca atatcaagga atgacctatg
      301 tctaccaaca cagtcaaacc agcaaacgtg gaagcagtac ctttctttgc tcgtttctta
      361 gaagagcaag ttacagaagt gtctgatact tctcctcgga atactctaaa gtatccttcc
      421 gattgggaag aatactaaac ctagttagct tcatctaaca gtaagggagt aggagttatt
      481 aaataactcc tactcctggt taacaaccaa tattcaggaa taataccatg tctacaaaca
      541 caacaaaagc tgcaaacatc gaagcagcac cattctttgc tcgcttctta gaagagcaag
      601 ttgctgaagt gtctgatact gctccttacg aaactaaaaa gtggccttcc gattgggaag
      661 aatactaaac ctagttagct tcatctaaaa ataagggatt aggagttatt aaataactcc
      721 tactcctggt taacaaccaa tattaaggaa tagtaccatg tctacaaaca caacaaaagc
      781 tgcaaacgtg gaagcagtac ctttctttgc tcgcttttta gaagagcaag ttgctgaagt
      841 gtctgatact gctccttacg aaagtagaaa gtatccttcc gattgggaag agtactaaac
      901 ctagttagct tcatctaaaa ataagggaat ggcagttatt aaataactgc aagctacttt
      961 tgaaaacgcg atcgcttcta tattacctaa tccataacat ggaggcgatc gcctttaaat
     1021 tcccgacttc tttaagaagt cgaggatcta gaaagatgtt aacatacctt aatatttata
     1081 tattttatgc acctgtctcg tgatgttgtt ttattaatca gccacagtgg tgatttcttc
     1141 acaatagata gagtggcaga agccttatca aaaaaagggg cgcaaccatt tcgtctagat
     1201 actgataagt ttcctttaga agtacaatta gcagcacatt ttgacaagtc taaaagctac
     1261 cacactatag aatataacaa ccaatctatc agtacagagc aggtgcaagc tgtgtggatg
     1321 cgccgcattt gggaaccaca attaggaaaa gaattagcac ccaagttccg cgaagcttgc
     1381 attaaagaat caaaagccac tttaaatggt ttttgggaca gcctcaaagg agctacttgg
     1441 gtagataatt tagaacgaat agattatgca ggtagcaaac tgcgtcaact gcgggttgca
     1501 tctgaagtag gttttactat tccccaaact ctggttacga ataaagccga agcagcaaga
     1561 gagtttttca agcaagtcaa cggcaaaatg gtaagcaagc ttttaactac tctttcctac
     1621 agtatggaag ctaactcctc gttctttctt tacaccagca ctgttaaaga agaagacttg
     1681 caagatgccg aatcactacg ctattgccca atggtttttc aagagcaaat ccccaagcag
     1741 caagaattgc gtgtggcgta tgtaaatggc aatgtatttg taggggcgct gaatgcagat
     1801 gtgtatgcaa cagctaaagc tgattggcgt aaaccaggtg ttgaagttgg tgcatggcaa
     1861 caccaccagg ttccggatga atttgtgcgt cgtttgcaag cttttatggg taaatttggg
     1921 ctgttgtttg gctcgttaga ttttatcctc acaccatcag gcgaatacgt ctttttggaa
     1981 aataaccccg taggagaatg gggaatgttg gagaaagatt tagacttgcc aatttcagat
     2041 gcgatcgcag atgccctact tcaaacaaac aattaaatat tcagacttca tactttacac
     2101 ttcataattc agacttcata cttcacactt tttatgaccg ttttaatagt cacatttagc
     2161 aaagacaacg aaagcattcc gctagtcatc aaagaaattg aggctagagg cgaaaaagcg
     2221 tttcggtttg atacagacag atatcccacc gaagtcaaac tagatattta ctgcggtgat
     2281 actgagcgtg taattattac tgatggcgaa caaaagctcg atttgagtga agtgtcttca
     2341 gtttggtatc ggcggatgcg ctacgggcag aaactccccg attcaatgga caagcaatac
     2401 agagatgcat caattcagga atgtcgcgtc agtgtcaggg gaatgattgc cagcctccca
     2461 ggatttcact ttgataaaat ggcaaatgtt gatcgggcta ataataaaca actacagtta
     2521 aaagttgcca aagaagtcgg acttttaact cctcgtaccc tgacttccaa caaccccgaa
     2581 gcagttaagc aattcgctca agagtgtgag caaggtatca ttaccaagat gctttcttcc
     2641 tttgctatct atgatgagca ggggcgagaa aatgttgtgt ttaccactcc aattacagaa
     2701 gatgatctgg agaatatgga aggactgcgt ttttgtccga tgacatttca ggaaaacgtg
     2761 cccaaagccc tagagttgcg gacaactatt gtgggacacc gcgtatttac agccgcagta
     2821 aattcgcaaa gcttggaagg atctacttac gactggcgca aagaagggaa agctttagtt
     2881 aaaaattgga aaccttacga attgccagaa gatattgaaa aaaagctgct caaactaatg
     2941 gctgagtttg gcttaaacta cggggcgatt gatattattg tcacccccga tggtcgccac
     3001 gtattcctgg aagtgaatcc agtcggggaa tttttctgga tggagatata ttcaccacac
     3061 tatcctattt cgcaggcgat cgcagaagta ctactaacta agaaaaatta gagaattgag
     3121 cattgttttc ttattttaca ccctacaggt actcagttaa aaaatacttt tgcagtagcg
     3181 tctggaacgg aaaattagcc gctactgcgt ctacatcccc tactgcttta aaagttggta
     3241 gtgggatttt attatttact tcatttatat ttactcaatt atttttacct aaaaattaat
     3301 aattatttat ataatatata gatgattctc tgaatttgat attaattatt aaagaccatt
     3361 tcaaaactcc tagtttaatt aaaaacagct acatctttag aatatgcaaa ctccatctgt
     3421 acgcgagcaa actacaacaa atcctttttc agctattacc caattttggg aggatgtgaa
     3481 agtagttgct caaccttatt ggtatccaac aaaagcagaa ggaagagcat tttccgatgt
     3541 gattcgctca tggggagcgc tcattctttt aatattattg atattgggat ttgtcggtat
     3601 agatgctgca aatagctact ggaatcgcta tgtaactgat atcattattg aagagagaaa
     3661 ccttgataaa tattatagta ctttatggct atctaatatc attcttgtag taagcgtcat
     3721 catagtgact ttcttaagat atgttaagaa aaaaattatt cttgattggt acaaatggct
     3781 aaataatcat attttaaaaa tatatttgag tcatcaagct tattataaaa ttaattttaa
     3841 atctgatgta gataatccag accaacgcct gtcacaagaa atagaaccta ttatcagcaa
     3901 tgctttaaat ttttcaacta ccttcctaga aaaagttcta gtaatgggaa gttctataat
     3961 aattctctcg acaatttctg tagaaatagc tgtctattta gttatttata caattgtagg
     4021 taatttaata gctgtttact taaatcaata cttaaataaa attaatcaag aagaacttgc
     4081 gtttaaagca gactttgctt attgcctgac tcatgtccgt aatcacgctg aatcaattgc
     4141 tttttttcag ggagaacagg aagaattaaa cataattgaa cgccgattta ataatgtgct
     4201 aaaaacggct gaacacagga tgaattggga gagagggcaa gatgcttttg gtagagcata
     4261 tcagtcagca attggtgtat tttcggctta tattcttact cctttatttc ttcaggatca
     4321 aattgattat ggagaaatta accaaattag tataacttgc ttcatgtttt ctactgctct
     4381 gggggaacta atagctcaat ttggtgtttc aggtcgattt tctagttacg tacaacgttt
     4441 agcccagttt ttggatgcgt tacaagctgt tagtaaacaa ccagaaaatg tcagtactat
     4501 taaagtttta gaagaaaaac gtttggcttt tgaaaatgtt actttacaaa cgccaaatta
     4561 tgaacagaca attgttgaag atttgtcagt tgctgttggg ccaggtgaag ggttattgat
     4621 tgttggccct agtggtaggg ggaaaagttc tttattaaga gcgatcgctg gtttatggaa
     4681 tgcaggaact ggtcgtttag tgcgtcctcc tctcaaagaa gtcttatttt taccccaaag
     4741 accttacatt attttgggaa ctttgcgcga acagttgctt tatccccata cagataaaaa
     4801 aatgagcgac aaagaactcg aacagatttt gcgacaagtt aatctacaaa acttgcttgc
     4861 ccgtgtaaat ggttttgata cagaagtacc ttgggaaaat atcttgtctt taggagaaca
     4921 gcaacgcctc gcgtttgcaa ggttattaat tacacatcct agtttcacaa tcttagatga
     4981 agctaccagt gctttagatt taaataacga aggtaattta tatcaacaat tacaagaaac
     5041 gaaaacaact tttattagtg ttggacatcg ggaaagctta tttaattatc atcaatgggt
     5101 attagaactt tctcaagaat ctagctggaa acttgtttct atagatgaat atcgacaaca
     5161 aaaagcaatt gctattaaac caattgaaaa agagcaaatt acaatagaaa ttttgcctga
     5221 tcataaactg acaatagaac caacaaactc agcattaaca acaattgttg gactttctca
     5281 taaagaactt caagcattaa ccgactattc tcttgccact attagaacca aggcaagtca
     5341 aagaaaacct gtgactacaa aagataacgt tacataccgc tataacaaag acccgaaagt
     5401 attgaaatgg atcagcgact caagtacaca gtaaatcaga taggaaggtc gtagcatgga
     5461 aaaacttgtg acgacaagat taaatttagt gccttttacg cttgaagtag taaaagtagc
     5521 aatcatggga aatgataaat tagcatcatt tctaggggta aaagttttac ctgactggca
     5581 gagtgaagaa tttagagaaa ttttgccaga gattgcagat attctgtgta aatatcagtt
     5641 tcaacatgaa tggggatggg gaagtttaat cattcataaa gcagaaaata tgcttatcgg
     5701 ttatgttatg gttaaagtta ttccagatag ctcattttca cctactggtt ccttagaaat
     5761 tggctattat gtagctcgat catatcgact acagggctac gcgtctgaag ctacgaaagc
     5821 tgtgatagat tgggcgttag ctcaacctag tgtgcaaagt gtgactgctg gctgtaaccc
     5881 cgataatata gcttcaaagc gagtgctaga aaaaattgga atgcaactta tagaatcacg
     5941 cgaaaaagtg ctggtatgga aattaggcaa aacagcgaca gtttga
//
