BGC0002641: bacillothiazol A biosynthetic gene cluster from Bacillus velezensis FZB42
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Location: 2,868,415 - 2,887,865 nt. (total: 19,451 nt).
This entry is originally from NCBI GenBank CP000560.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002641
Short description bacillothiazol A biosynthetic gene cluster from Bacillus velezensis FZB42
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP000560.2
2868415 - 2887865
via Heterologous expression, Enzymatic assays
Compounds
  • bacillothiazol A
  • bacillothiazol B
  • bacillothiazol C
  • bacillothiazol D
  • bacillothiazol E
  • bacillothiazol F
  • bacillothiazol G
  • bacillothiazol H
  • bacillothiazol I
  • bacillothiazol J
  • bacillothiazol K
  • bacillothiazol L
  • bacillothiazol M
  • bacillothiazol N
Species Bacillus velezensis FZB42 [taxonomy]
References
Chemical products information
bacillothiazol A Evidence:
(no structure information available)
bacillothiazol B Evidence:
(no structure information available)
bacillothiazol C Evidence:
(no structure information available)
bacillothiazol D Evidence:
(no structure information available)
bacillothiazol E Evidence:
(no structure information available)
bacillothiazol F Evidence:
(no structure information available)
bacillothiazol G Evidence:
(no structure information available)
bacillothiazol H Evidence:
(no structure information available)
bacillothiazol I Evidence:
(no structure information available)
bacillothiazol J Evidence:
(no structure information available)
bacillothiazol K Evidence:
(no structure information available)
bacillothiazol L Evidence:
(no structure information available)
bacillothiazol M Evidence:
(no structure information available)
bacillothiazol N Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • RBAM_027420
  • ABS75100.1
 2868415 - 2870064 (-) AMP-binding protein
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    • RBAM_027430
    • ABS75101.2
    		 2870071 - 2871183 (-) winged helix-turn-helix transcriptional regulator
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      • RBAM_027440
      • ABS75102.2
      		 2871193 - 2873937 (-) MBL fold metallo-hydrolase
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        • RBAM_027450
        • ABS75103.1
        		 2873990 - 2884225 (-) non-ribosomal peptide synthetase
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          • RBAM_027460
          • ABS75104.2
          		 2884222 - 2885316 (-) SagB/ThcOx family dehydrogenase
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            • RBAM_027470
            • ABS75105.1
            		 2885228 - 2885932 (-) thioesterase
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              • RBAM_027480
              • ABS75106.1
              		 2886198 - 2887865 (+) MFS transporter
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                Biosynthesis information

                Biosynthetic modules

                Name
                Unk01
                Type
                nrps-type1
                Genes
                RBAM_027450
                Substrates
                cysteine (evidence: Sequence-based prediction, Structure-based inference)
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk02
                Type
                nrps-type1
                Genes
                RBAM_027450
                Substrates
                cysteine (evidence: Sequence-based prediction, Structure-based inference)
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk03
                Type
                nrps-type1
                Genes
                RBAM_027450
                Substrates
                cysteine (evidence: Sequence-based prediction, Structure-based inference)
                Integrated Monomers
                Domains
                adenylation
                Annotation changelog

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Entry added
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2022-09-15
                Added NRP substrate specificities
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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