BGC0002657: deoxyhangtaimycin biosynthetic gene cluster from Streptomyces spectabilis
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Location: 8,843,425 - 8,924,101 nt. (total: 80,677 nt).
This entry is originally from NCBI GenBank CP023690.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002657
Short description deoxyhangtaimycin biosynthetic gene cluster from Streptomyces spectabilis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
  • NRPS (Type I)
Loci
CP023690.1
8843425 - 8924101
via Knock-out studies, Enzymatic assays
Compounds
  • deoxyhangtaimycin
Species Streptomyces spectabilis [taxonomy]
References
Chemical products information
deoxyhangtaimycin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CP982_37530
  • QEV63697.1
 8843904 - 8844587 (-) HAD family phosphatase
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    • CP982_37535
    • QEV63698.1
    		 8844632 - 8845123 (-) Lrp/AsnC family transcriptional regulator
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      • CP982_37540
      • QEV63699.1
      		 8845303 - 8847258 (+) APC family permease
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        • CP982_37545
        • QEV63700.1
        		 8847471 - 8848979 (+) FUSC family protein
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          • CP982_37550
          • QEV63701.1
          		 8849010 - 8850314 (-) phytase
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            • CP982_37555
            • QEV63702.1
            		 8850380 - 8851033 (-) hydrolase
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              • CP982_37560
              • QEV63703.1
              		 8851331 - 8852371 (+) lactonase family protein
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                • CP982_37565
                • QEV63704.1
                		 8852462 - 8853391 (-) hypothetical protein
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                  • CP982_37570
                  • QEV63705.1
                  		 8853629 - 8854633 (-) ATPase
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                    • CP982_37575
                    • QEV63706.1
                    		 8854630 - 8855307 (-) uracil-DNA glycosylase
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                      • CP982_37580
                      • QEV63707.1
                      		 8855400 - 8855891 (-) isoprenylcysteine carboxylmethyltransferase family protein
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                        • CP982_37585
                        • QEV63708.1
                        		 8855934 - 8857019 (-) exo-alpha-sialidase
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                          • CP982_37590
                          • QEV63709.1
                          		 8857193 - 8858146 (-) homocysteine S-methyltransferase
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                            • CP982_37595
                            • QEV63710.1
                            		 8858143 - 8860227 (-) dipeptide ABC transporter ATP-binding protein
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                              • CP982_37600
                              • QEV63711.1
                              		 8860240 - 8861157 (-) ABC transporter permease
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                                • CP982_37605
                                • QEV63712.1
                                		 8861154 - 8862104 (-) ABC transporter permease
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                                  • CP982_37610
                                  • QEV63713.1
                                  		 8862101 - 8863954 (-) peptide ABC transporter substrate-binding protein
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                                    • CP982_37615
                                    • QEV63714.1
                                    		 8864181 - 8865392 (+) ROK family transcriptional regulator
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                                      • CP982_37620
                                      • QEV63715.1
                                      		 8865395 - 8866987 (+) M81 family peptidase
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                                        • CP982_37625
                                        • QEV63716.1
                                        		 8867044 - 8867859 (+) ABC transporter substrate-binding protein
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                                          • CP982_37630
                                          • QEV63717.1
                                          		 8867975 - 8868979 (+) hypothetical protein
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                                            • CP982_37635
                                            • QEV63718.1
                                            		 8869135 - 8870637 (+) hypothetical protein
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                                              • CP982_37640
                                              • QEV63719.1
                                              		 8870682 - 8871758 (+) hypothetical protein
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                                                • CP982_37645
                                                • QEV63720.1
                                                		 8871736 - 8873109 (+) hypothetical protein
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                                                  • CP982_37650
                                                  • QEV63721.1
                                                  		 8873369 - 8874163 (-) SARP family transcriptional regulator
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                                                    • CP982_37655
                                                    • QEV63722.1
                                                    		 8874300 - 8877155 (-) helix-turn-helix transcriptional regulator
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                                                      • CP982_37660
                                                      • QEV63723.1
                                                      		 8877317 - 8877514 (-) hypothetical protein
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                                                        • CP982_37665
                                                        • QEV63724.1
                                                        		 8877736 - 8878593 (-) aminoglycoside phosphotransferase family protein
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                                                          • CP982_37670
                                                          • QEV63725.1
                                                          		 8878773 - 8881994 (+) amidohydrolase
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                                                            • CP982_37675
                                                            • QEV63726.1
                                                            		 8882146 - 8882841 (+) murein L,D-transpeptidase
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                                                              • CP982_37680
                                                              • QEV63727.1
                                                              		 8882909 - 8883994 (-) NADH:flavin oxidoreductase/NADH oxidase
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                                                                • CP982_37685
                                                                • QEV63728.1
                                                                		 8884209 - 8884565 (+) transcriptional regulator
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                                                                  • CP982_37690
                                                                  • QEV63729.1
                                                                  		 8884629 - 8886074 (-) NADP oxidoreductase
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                                                                    • CP982_37695
                                                                    • QEV65162.1
                                                                    		 8886486 - 8886926 (+) hypothetical protein
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                                                                      • CP982_37700
                                                                      • QEV63730.1
                                                                      		 8886997 - 8887749 (-) DUF305 domain-containing protein
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                                                                        • CP982_37705
                                                                        • QEV63731.1
                                                                        		 8887868 - 8889376 (+) hypothetical protein
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                                                                          • CP982_37710
                                                                          • QEV63732.1
                                                                          		 8889428 - 8890045 (-) TetR/AcrR family transcriptional regulator
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                                                                            • CP982_37715
                                                                            • QEV63733.1
                                                                            		 8890325 - 8890570 (+) DUF2630 family protein
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                                                                              • CP982_37720
                                                                              • QEV63734.1
                                                                              		 8890587 - 8891306 (-) HAD family hydrolase
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                                                                                • CP982_37725
                                                                                • QEV63735.1
                                                                                		 8891374 - 8892081 (-) phosphatase PAP2 family protein
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                                                                                  • CP982_37730
                                                                                  • QEV63736.1
                                                                                  		 8892115 - 8893047 (-) M56 family peptidase
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                                                                                    • CP982_37735
                                                                                    • QEV63737.1
                                                                                    		 8893163 - 8893708 (-) DUF5134 domain-containing protein
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                                                                                      • CP982_37740
                                                                                      • QEV63738.1
                                                                                      		 8893892 - 8895559 (+) FUSC family protein
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                                                                                        • CP982_37745
                                                                                        • QEV63739.1
                                                                                        		 8895595 - 8896125 (+) MarR family transcriptional regulator
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                                                                                          • CP982_37750
                                                                                          • QEV63740.1
                                                                                          		 8896132 - 8896518 (-) VOC family protein
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                                                                                            • CP982_37755
                                                                                            • QEV63741.1
                                                                                            		 8896624 - 8897178 (+) GNAT family N-acetyltransferase
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                                                                                              • CP982_37760
                                                                                              • QEV65163.1
                                                                                              		 8897200 - 8897883 (-) glycerophosphodiester phosphodiesterase
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                                                                                                • CP982_37765
                                                                                                • QEV63742.1
                                                                                                		 8898162 - 8898908 (-) 1-acyl-sn-glycerol-3-phosphate acyltransferase
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                                                                                                  • CP982_37770
                                                                                                  • QEV63743.1
                                                                                                  		 8899541 - 8900944 (+) hypothetical protein
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                                                                                                    • CP982_37775
                                                                                                    • QEV63744.1
                                                                                                    		 8900941 - 8901711 (+) SDR family NAD(P)-dependent oxidoreductase
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                                                                                                      • CP982_37780
                                                                                                      • QEV63745.1
                                                                                                      		 8901708 - 8902778 (+) low specificity L-threonine aldolase
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                                                                                                        • CP982_37785
                                                                                                        • QEV63746.1
                                                                                                        		 8902896 - 8903501 (+) transglutaminase family protein
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                                                                                                          • CP982_37790
                                                                                                          • QEV63747.1
                                                                                                          		 8903687 - 8905930 (+) hypothetical protein
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                                                                                                            • CP982_37795
                                                                                                            • QEV63748.1
                                                                                                            		 8906020 - 8906709 (+) cytoplasmic protein
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                                                                                                              • CP982_37800
                                                                                                              • QEV63749.1
                                                                                                              		 8906745 - 8907473 (-) 1-acyl-sn-glycerol-3-phosphate acyltransferase
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                                                                                                                • CP982_37805
                                                                                                                • QEV63750.1
                                                                                                                		 8907667 - 8908068 (+) thioredoxin
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                                                                                                                  • CP982_37810
                                                                                                                  • QEV63751.1
                                                                                                                  		 8908312 - 8908818 (+) flavin reductase
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                                                                                                                    • CP982_37815
                                                                                                                    • QEV63752.1
                                                                                                                    		 8909050 - 8909838 (+) electron transfer flavoprotein beta subunit/FixA family protein
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                                                                                                                      • CP982_37820
                                                                                                                      • QEV63753.1
                                                                                                                      		 8909898 - 8910860 (+) electron transfer flavoprotein subunit alpha/FixB family protein
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                                                                                                                        • CP982_37825
                                                                                                                        • QEV63754.1
                                                                                                                        		 8910921 - 8911826 (-) endonuclease/exonuclease/phosphatase family protein
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                                                                                                                          • CP982_37830
                                                                                                                          • QEV63755.1
                                                                                                                          		 8912112 - 8913419 (+) aldolase
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                                                                                                                            • CP982_37835
                                                                                                                            • QEV63756.1
                                                                                                                            		 8913490 - 8914572 (-) LacI family transcriptional regulator
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                                                                                                                              • CP982_37840
                                                                                                                              • QEV63757.1
                                                                                                                              		 8914907 - 8915878 (+) ROK family protein
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                                                                                                                                • CP982_37845
                                                                                                                                • QEV63758.1
                                                                                                                                		 8915965 - 8917986 (-) alpha-galactosidase
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                                                                                                                                  • CP982_37850
                                                                                                                                  • QEV63759.1
                                                                                                                                  		 8918299 - 8919567 (+) carbohydrate ABC transporter substrate-binding protein
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                                                                                                                                    • CP982_37855
                                                                                                                                    • QEV63760.1
                                                                                                                                    		 8919606 - 8920520 (+) sugar ABC transporter permease
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                                                                                                                                      • CP982_37860
                                                                                                                                      • QEV63761.1
                                                                                                                                      		 8920517 - 8921446 (+) carbohydrate ABC transporter permease
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                                                                                                                                        • CP982_37865
                                                                                                                                        • QEV63762.1
                                                                                                                                        		 8921550 - 8922335 (+) hypothetical protein
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                                                                                                                                          • CP982_37870
                                                                                                                                          • QEV63763.1
                                                                                                                                          		 8922431 - 8923147 (+) VOC family protein
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                                                                                                                                            • CP982_37875
                                                                                                                                            • QEV63764.1
                                                                                                                                            		 8923156 - 8923338 (-) hypothetical protein
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                                                                                                                                              Biosynthesis information
                                                                                                                                              Annotation changelog

                                                                                                                                              Entry version: 1

                                                                                                                                              Date
                                                                                                                                              Changes
                                                                                                                                              Submitters
                                                                                                                                              Reviewers
                                                                                                                                              2022-09-15
                                                                                                                                              Entry added
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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