LOCUS       BGC0002665             10915 bp    DNA     linear   BCT 13-JAN-2020
DEFINITION  Pseudomonas syringae pv. maculicola str. ES4326 chromosome, complete
            genome.
ACCESSION   BGC0002665
VERSION     BGC0002665
KEYWORDS    .
SOURCE      Pseudomonas syringae pv. maculicola str. ES4326
  ORGANISM  Pseudomonas syringae pv. maculicola str. ES4326
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     Bacteria and source DNA available from David Baltrus.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:10:27
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10915
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5915]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5915
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10915
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..10915
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002665"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..10915
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            654..1865
                     /locus_tag="PMA4326_007935"
     CDS             654..1865
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019331910.1"
                     /locus_tag="PMA4326_007935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="QHE96552.1"
                     /transl_table=11
                     /translation="MSSQVPENTPSTKGLFGLFCLASYLLSLSYGTTFLLALMLGSHGG
                     SESDAGTVISVAMLSTFLAVIFSGHLTDIIGAPRAIAAGGLTLMIACIGFAMTPTYGPA
                     LLIFGLILGFGWGVFYTLGPIIVAMIIEPARRVKYFALLSGSMMSGIGTGPLAGRGAVA
                     MGYPVESAFVVAAAASLLGAVVFFLIAPKIRLQQAVLGPVAVCRITTGAAARVLRSKAF
                     FPIVMVGLGGAIFGGLSSFQTSYAALHHLDYSLFFLGFMCAAISCRLLIAGFIVKRDAY
                     LSSCVLTSLMIVSILMFVFSVESPFSYLLAAIILGVGYGLTYSVINGLAANEAPNGLTA
                     QSLLLFSLSYFVGVFGFPLLAGKIIVAYGMPSLLYTILSVALLNGCIALGRLAWRKVAV
                     AAIA"
     gene            1949..2692
                     /locus_tag="PMA4326_007940"
     CDS             1949..2692
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701512.1"
                     /locus_tag="PMA4326_007940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="QHE96553.1"
                     /transl_table=11
                     /translation="MPVNAPEVISLEVVGDGLASNNAAWSFGGDTPKHFDSHVSKSVPK
                     YKDGHDIVLSLSDFFIKADSVCYELGSSTGTLTRQLAERHGRSGKWVGIDVEEAMTQQA
                     NQSLGCAPISNVTFVTDDILTFPYEKSDFIVAYYTVQFVHPRVRQELFNRIYESLNWGG
                     AFVLFEKVRGPDARFQDVISSLYVDYKMQQGYTPSEILAKTRSLKGVLEPFSTAGNQDM
                     LARAGFKDVMSIFKYICFEGFFCIK"
     gene            2706..3623
                     /locus_tag="PMA4326_007945"
     CDS             2706..3623
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007252212.1"
                     /locus_tag="PMA4326_007945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="QHE96554.1"
                     /transl_table=11
                     /translation="MNDWAISHYLDVLHMDSGYQAVALDCELCGSEHHEVLLPRICGPE
                     PHGVDLPVLGCQACGHIFQKYRFDAQFYKDYYDKFYRLKLFGNSAPEKAFFLDQIRRGE
                     YLRQSLREYLPESGRLLDVGCSAGGLMIPFAKRGWSVTGNDPDRAYVEYGKQIGLNIEL
                     TAAEEMDAAGDVDLIIINGSLEHMYDVHCVMQRCRQASSENGLLLIEGRALGHGLEQGM
                     LTHNHRRYLSGTSIELLMRMHGWEPLLITEQPLCGPTRPGAVFVLGRCAAPSDDVQLER
                     VKAQGRERLDSYYRERFRALVLPS"
     gene            3620..4762
                     /locus_tag="PMA4326_007950"
     CDS             3620..4762
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiaglutamate_G_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007252213.1"
                     /locus_tag="PMA4326_007950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase M50"
                     /protein_id="QHE96555.1"
                     /sec_met_domain="Thiaglutamate_G_RRE (E-value: 1.4e-53,
                     bitscore: 168.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHASDVSEVMKQTSIASCLRNDIVVSERVEADGRLRYKLYDPSN
                     DIGFELGKTEYALARLFDGVSTHEEISRYAETRHRIKVSQTKLVQFESRLLSLNILSGV
                     DGDLEKLRDPATGITYGPLKKYLLINLVKMNPQPGLDYVYPSVRWICSVPFCLAMLAAC
                     LVSYVYLGMHFGAFQEDVLAVYVHSNQWLWWHFPVILSSIALHEFGHALACRHYKVQVS
                     DFGIGIYLLLATGWVRPVQEQWSSLPRYQRIVTILAGPLVSLVYATAGIVIWAAYGEAQ
                     GNLLALSIVMIVASFISLIPTLLPMFNGDTYLAITELINEPRLRQRSFNYLKARLRGAP
                     CETSVRLQRLYLSTVSITCLGWVLVWGFVLQTLFRVFHNQ"
     gene            5001..5915
                     /locus_tag="PMA4326_007955"
     CDS             5001..5915
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007252215.1"
                     /locus_tag="PMA4326_007955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 family protein"
                     /protein_id="QHE96556.1"
                     /sec_met_domain="DUF692 (E-value: 1.5e-41, bitscore: 131.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFVKPAPIGVGIQYNPEILDWFPFEDIQVDILEILLDNIMAPM
                     DGPQIIKPSAQAMIERLGQKFTLLAHSNYGCDFGFSALEETAAVQRHVPLAKMLNSPWV
                     ANHCFYGDQSWLDIWSSPIQFSAAEVARCADRAQSLQTLYGMPLAHENAAYYLECPGAE
                     MREAEFLARLVQRSGTFLHLDLHNIYTNHLNLKGFDLKDYMDTLPLDKVISVHLAGGSW
                     HGGLYHDWHDACVPEPVWDLYEDLLSRAQPSAVILEYQGQAHHAQTRIMDASDESMIVR
                     DVQRAQAIWSRYNRHPQERQYGS"
     gene            5905..6714
                     /locus_tag="PMA4326_007960"
     CDS             5905..6714
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiaglutamate_I_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701508.1"
                     /locus_tag="PMA4326_007960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="QHE96557.1"
                     /sec_met_domain="Thiaglutamate_I_RRE (E-value: 5.4e-54,
                     bitscore: 169.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAEQVWKLWRRVLRDERLQAQLFSATDATHWLSGFSESESKILS
                     VYAQQFDRVKWFVENYQFRLVNSFLNALETGAPLSLRALLHINVDLNAQSKAFLRDRQW
                     RDYGPQVYTYCEDVLGFLAEADELQGYPEILDLMRLERESVRLYRGLVDPESLPADNRY
                     QRTSMARLYETRFALSGWLRQKDQLGLTRLPESTEHVLIYLPTLQARHKFTLINAQAAR
                     LYNCLEQPQSAAGLFMLINSDSASVPGSADLALLDRLEQLNAIRKPL"
     gene            6718..9165
                     /locus_tag="PMA4326_007965"
     CDS             6718..9165
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiaglutamate_B_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701507.1"
                     /locus_tag="PMA4326_007965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="QHE96558.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1e-26, bitscore:
                     82.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Thiaglutamate_B_RRE (E-value: 1.5e-48,
                     bitscore: 152.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESSHYFWLRSTGFAVHHLTRLGKMAELPLLKDFETDYRSLNTLR
                     DSLLEKSISHSSQACRKLIRKLNENLPLQVSDLPEALRDDAVDELAHWNERLGRLKQRV
                     EVDQEYAVFLESARQALIDFVNDEDVEQAVFISNPTALTRLRELRQERHARTDSRKKQK
                     LRLAWSYAQRFCSKNDTSSFFGPLAWGRFDRTQVEHVRITQHGPGWIRERHTFFESWVV
                     QRLVEQLNRHCVDVQFMPLQLNPGCFLNQDTLHLPVNKRRQVSALTARVLGYIQCQSAV
                     APTLFGLQAELQDVSAGQLRDLIDHLVAQQIVRRGWQISPRERKPVQVLHTFLADARLS
                     DDFRTQWHERLSGLEAIRQDYATGDLAVRIASLDKLNRLLGEAGVDISRESGAMYVGRY
                     PVYEDCSRNIDISLGGALLDQVNADLAPLMRIHQWLIKACARQLHGFYAQVWQRLQAED
                     EHNPVNFLAFLGAVQPVIAHAEAGIIEELDAVLADAWQQVLSDKHDPEQVQLTHEDIER
                     LIVELNTRLDVRTFSVFGSHFHSPDFLISSTSTDALNQGDYSIILGEVHPGVHTLSQPV
                     AEPFGPFNKEIEQEVRQIFDGPRLVLADSPDSYQRSHIDWPLLECYQQLILPSGGGCVP
                     ADQRFAVGRARLVMNEGRLRVEDIAGQFSEDLVCVYPTPMHRLGFALAGSVVAKNDRRR
                     IGLGKTLYKRASWWFSPEQLPCSEFSVDKLDDVLAWRAWAVEHGLPRYVFAKIDIEPKP
                     IFIDFDNPLSLDGVSNSMKKAGHVKFSEMCPAPDQLWLEETRGHFCCEIRTTFRDNGVT
                     RDE"
     gene            9158..10423
                     /locus_tag="PMA4326_007970"
     CDS             9158..10423
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 146.3; E-value: 1.7e-44)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019331902.1"
                     /locus_tag="PMA4326_007970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="QHE96559.1"
                     /transl_table=11
                     /translation="MNNSSAMDGSQQKLKSSFFLLFLTIFIPFGLGHFVSYLFRTVNAV
                     IYVDLQTDLSLPASSLGLLTGVYFLTFAAAQIPLGVMLDRYGPRSVQAPMLLFAVAGSV
                     IFSVSSSEAGLLIGRGLIGLGVAGSLMSAIKACAIWLPVERLPLSTACLLSIGGLGAMA
                     STTPLHALLSWLTWREAFLVLALLTFCVAVVIHFSVPKTYQSKNTRYGDMFAAVGKLYS
                     SWTFWRLALYSVFAHAIYMSVLSLWMGPWLRDMAGLSDSAMASVLLFGAIAIVAGSLTF
                     GAITDYLRRFGVQPIMICGTGMLIFIGFQVLMVSDLPVSPYLIAMGFSFFGTSTTMNYA
                     IVAQSVSPELAGRVSSSFNLVVFVLAFCLQWLMGVVLNLWPVAQGAGHPAEAYQWSLGL
                     MIALQVPGLLLWLSFRPWQRKV"
ORIGIN
        1 tgcggcattc ggtgcctttg ctcgttgttc tcctcgttac gaacacttga tcgaggggct
       61 ggagcgtgct gattcgataa cggcggatgc tcacaagtgg cttaacgttc cctatgactg
      121 tggaattgcc ctgacccgac atacggcgtt tcatgagcgg agcttttccg ctgacgcgcc
      181 ctatgtgccc atggggggcg agcttcctgc tttcatgaac cgaggtgttg aacagtcgcg
      241 tcgctatcgt gcgttgccgt tatggatgac gcttatggct tacggcaagt cgggttaccg
      301 cgagttggta gagcgtaatt gtgatgttgt acgccagatc gcttcgtgga ttgacgggtg
      361 tgaatactac gacgtgttgt gccctgtcta tttgaacatc gtgatgtttc gctgccgacg
      421 tgtcggcggg cgtgatcatg acgcgcacag cgtggcagtg ctggaaagaa tcaatgccac
      481 aggtgcgctg tttcttacgc ccagtacgta caacggggaa aaggtatttc gtctggctgt
      541 ctgtaactgg atgaccacac gcagtgatgt cgcaattgtg atcaatgcct tacaccacgc
      601 ggtggctggt tattgagagc agcactgtta tcaaacgata aggaatgtca tacatgtctt
      661 cgcaagtgcc tgaaaatacc ccttcgacca aggggctgtt cggcctgttt tgcctggcca
      721 gctatctgct gtccctgtct tacggcacca cttttctact ggccctgatg ctgggctctc
      781 atggcggaag cgagtctgac gcaggcacag tgatttcagt ggccatgctg agcacatttc
      841 tcgccgtcat tttttcaggg cacctgaccg atatcatcgg tgcgccccgg gctatcgctg
      901 ccggaggtct gacgttgatg attgcatgca tcgggtttgc catgaccccg acgtatggcc
      961 cggcattatt gatattcggt ctgatactgg gtttcggttg gggtgtgttc tacacactgg
     1021 ggccgatcat tgttgcaatg atcatcgagc ctgcgcgtcg ggtgaagtat ttcgctttgc
     1081 tgtccggcag catgatgagt gggatcggta ccgggccttt ggcagggcgc ggtgcagtgg
     1141 caatggggta tccggttgaa tcggcgttcg tcgtcgcggc cgctgccagc ctgctgggtg
     1201 cagtcgtgtt tttcctgata gctccgaaaa tcaggctgca acaggctgtt ctcgggcctg
     1261 tggccgtgtg ccgcatcact acaggtgctg ccgctcgtgt actgcgctcc aaggcgttct
     1321 ttcctatcgt gatggtggga ttgggcggcg caatcttcgg cgggctttcc agctttcaga
     1381 cctcctacgc cgcattgcat catctggact attcgctgtt tttcctcgga ttcatgtgtg
     1441 cggccatctc ttgccgattg ttgattgccg ggttcatcgt caagcgtgat gcttacctgt
     1501 cttcctgcgt actgacatcc ctgatgattg tttcgatact gatgtttgtg ttctcggttg
     1561 agtcgccatt cagttatttg ttggccgcga tcattcttgg cgtgggttat ggcttgacgt
     1621 attcggtgat caacggcttg gcggctaatg aagcgcctaa cggactcacc gcacagtcct
     1681 tgttgttatt cagtttgtct tactttgtag gcgtgttcgg ttttccactg ttggccggaa
     1741 aaataatcgt ggcttacggc atgccctcac tgctgtatac gattctctcg gtagcccttt
     1801 taaacgggtg tattgcgttg ggccgtcttg cctggcgcaa ggtggctgtc gccgccatag
     1861 cctgaccgta aacgtttcag tcaaactgca tcgcgtgacg cgctgcagtt ttcggtgttc
     1921 ctgtgcaagg taagcaagga gattcattgt gcctgttaat gcgcctgaag taataagtct
     1981 tgaagtggtc ggggatggac tggcttcaaa taacgcagcc tggagttttg gcggtgatac
     2041 gcccaaacat ttcgactcgc atgtttcgaa atcggttccc aagtacaagg acggtcacga
     2101 tatcgttctt tccttgagcg acttctttat caaggctgac agcgtctgtt atgaacttgg
     2161 aagttcgacc ggcacattga cacggcaatt ggcagaacgt cacgggcgtt caggcaaatg
     2221 ggtgggtatc gatgtcgaag aggccatgac tcaacaagcc aatcaatcac tcggctgtgc
     2281 gcccatcagt aacgtcacct ttgtgaccga cgacatcctt acctttccgt atgagaagag
     2341 cgatttcatc gtcgcgtatt atacggttca gtttgtccat ccccgcgttc gccaggagct
     2401 gttcaatcgt atttacgagt ctctgaactg ggggggtgca tttgtgctgt tcgagaaagt
     2461 cagggggccg gatgctcggt ttcaggatgt gatcagcagt ttgtatgtcg actacaagat
     2521 gcagcagggc tatacgccga gcgagatcct ggccaagacg cgtagtctta aaggtgtgct
     2581 ggaaccgttc tccacggccg gcaatcagga catgctcgcc cgagccggtt tcaaggacgt
     2641 gatgagcatt ttcaaataca tttgttttga aggtttcttc tgcatcaagt aacagggacg
     2701 ttgcgatgaa cgattgggct atcagccatt acctggatgt gttgcacatg gacagcggtt
     2761 atcaagccgt tgcactggac tgcgaactct gcggcagtga acaccatgag gtgttgctgc
     2821 cacgtatctg cggtcctgaa ccccacggcg ttgatttgcc tgtgttgggg tgtcaggcgt
     2881 gcggccatat ttttcaaaaa tatcgttttg atgcgcagtt ttacaaagac tactacgaca
     2941 agttttatcg cttgaaactg ttcggcaaca gcgcgccgga aaaagcgttt tttctcgacc
     3001 agattcgtcg tggagaatac ctgcgtcaga gcctgcgcga atacctgcca gagagtggtc
     3061 gcctgctgga tgtcggatgt tcagccggtg gcctgatgat cccttttgcc aagaggggct
     3121 ggtctgtcac cggcaatgac cctgatcgcg cttatgtcga atacggaaaa cagatcggcc
     3181 tgaatatcga gctgacagcg gccgaagaaa tggacgccgc aggcgatgtc gatctgatta
     3241 tcatcaatgg ctcgctggaa catatgtacg acgtgcattg cgtcatgcag cgctgtcggc
     3301 aggcgtcgtc ggaaaacggt ctgttattga ttgaaggccg cgccctgggt cacggcctgg
     3361 agcagggcat gctgacccac aatcatcggc gttatctcag cggcaccagc atcgaactgc
     3421 tgatgcgcat gcacggctgg gagccgctgc tgatcaccga gcaaccgtta tgcgggccta
     3481 ctcgacctgg cgcggttttc gtccttggtc gatgcgcagc cccgtcggat gatgtgcagc
     3541 tcgaacgtgt caaggcgcaa gggcgtgagc gcctggacag ttactaccgg gagcgcttcc
     3601 gggcgctggt gttgccatca tgacacacgc ttccgatgtg tccgaggtta tgaaacagac
     3661 ttcaattgcg tcctgtctgc gcaacgatat tgttgtcagc gagcgtgtgg aggcagacgg
     3721 ccggttgcgc tacaagcttt acgaccccag taacgatatc ggttttgagt tgggtaaaac
     3781 cgagtatgca ctggcccgcc tttttgatgg tgtatccaca cacgaagaga tctcccgata
     3841 cgctgaaacc cggcaccgca tcaaggtcag tcagacgaaa ctggtgcagt ttgaaagtcg
     3901 cctattgagt ctgaatattc tgtcgggggt agatggcgat cttgaaaaac ttcgtgatcc
     3961 cgcgaccggt attacctatg ggcctttgaa gaaatacctg ctgatcaacc tggtcaagat
     4021 gaatccgcag ccgggcctgg actatgttta ccccagcgtg cgctggatat gcagcgtacc
     4081 gttttgtctg gcgatgcttg cggcgtgttt ggtcagctac gtctacctgg ggatgcactt
     4141 cggcgcattt caagaagatg ttctcgcggt gtatgtgcac agcaatcaat ggctgtggtg
     4201 gcattttccg gtcatcctca gttctatcgc actgcacgag ttcgggcatg ccctggcctg
     4261 tcgacattac aaggttcagg tcagtgattt cgggatcggc atttatctgt tgctggccac
     4321 cgggtgggtg cggccggttc aggaacaatg gagttcgttg ccgaggtatc agcgcatcgt
     4381 caccattttg gccgggccac tggtcagcct tgtttacgcc actgcaggca ttgtgatctg
     4441 ggctgcttac ggtgaagcgc aaggtaactt gcttgcgctg tcgattgtga tgattgtggc
     4501 atcgttcatc tctctgattc caaccttgtt gccaatgttc aatggcgaca cttacctggc
     4561 catcaccgaa ctcatcaacg agccccggtt aaggcagcgc tctttcaact atttgaaagc
     4621 acgcttgcgc ggggcacctt gtgaaacgtc agtccggctc caacgccttt atctgagcac
     4681 tgtatcgatc acctgtcttg gctgggtgtt ggtgtggggc ttcgtgctgc agacgctttt
     4741 tcgtgtattt cataaccagt gaggatttac ccatgggaca acccaacgtg cagtccgttg
     4801 aaaaccagca agcgtccggc gatgtaaaag atctcgaaaa cactccgcag gccacagagg
     4861 aggcgttgtt tgaagagttt gacctggatg acattgaagt catcgagagc aaggtctttg
     4921 cctgagtgcg ccatgccctc ttgcgtgccg gattgtaggg atacgcagga gggcttcttt
     4981 catcagtgcg agtgttagcc atgcctgatt tcgtcaagcc cgcgcctatc ggagtgggta
     5041 tccagtacaa ccccgaaata ctggactggt ttccattcga ggatatccag gtggatattc
     5101 tggagatttt gctcgataac atcatggcgc ccatggatgg cccgcaaatt atcaagcctt
     5161 ctgcccaggc aatgattgag cggctagggc aaaaatttac cttgctggct cactccaatt
     5221 acggctgcga ttttggtttc agtgccctcg aagaaacagc ggcggtgcag cgccatgtac
     5281 ctctggcaaa aatgctcaac agcccttggg tggccaacca ttgtttctat ggggatcagt
     5341 cctggctgga tatctggagc agtcccattc agttctccgc agccgaagtg gcgcgttgtg
     5401 ccgatcgcgc acagtcgttg cagacgcttt atggcatgcc gctggctcat gaaaatgccg
     5461 cctactacct tgaatgccca ggcgccgaaa tgcgtgaggc cgagtttctg gcaagactgg
     5521 tgcagcgctc agggactttt cttcaccttg acctgcacaa catttacacc aaccacctca
     5581 atctgaaagg tttcgatctc aaggactaca tggacacgct gccgctggac aaggtgattt
     5641 cggtgcatct ggccggagga agctggcacg gcggcctgta tcacgactgg catgacgcct
     5701 gcgtgcccga gccggtctgg gacttgtacg aagacctgct ttcgcgtgca cagccctctg
     5761 ctgtgattct tgagtatcag gggcaggcgc atcatgccca gactaggatc atggatgcgt
     5821 ccgacgagtc gatgattgtc agggatgtcc agcgtgctca ggcaatctgg agtcgttaca
     5881 acaggcatcc gcaggagcgt cagtatggaa gctgaacagg tatggaaact gtggcggcgc
     5941 gttctgcgcg atgagcgcct tcaggcgcag ttgttttcgg ctaccgatgc cacgcactgg
     6001 ttgtcaggtt tcagcgagtc cgaaagcaag atcctctcgg tgtatgcgca gcagtttgac
     6061 cgcgtcaaat ggttcgtcga gaactatcag ttccggctgg tgaactcttt tttgaacgcg
     6121 ctggagaccg gcgcgccctt gtcgttgcgg gcgttgctgc acataaatgt ggacctgaat
     6181 gcgcaatcga aggccttcct gcgtgacagg cagtggcgcg attacgggcc gcaggtctat
     6241 acctattgtg aagatgtact gggtttcctt gccgaggcgg atgagctgca gggttatcct
     6301 gaaatccttg atctgatgcg gctggagcgc gaatcggttc gcctgtatcg ggggttggtc
     6361 gatcctgagt ccttgccggc agacaaccgt tatcagcgca cctcaatggc tcgtctttac
     6421 gagacacgtt ttgccctgtc tggctggctc agacagaagg atcagttggg cctgacacgt
     6481 ctgcccgaga gcaccgagca tgtgctgatc taccttccca cgcttcaggc tcgtcacaag
     6541 ttcactttga tcaacgcgca ggctgcccgg ctttacaact gcctggagca acctcagtcc
     6601 gctgccgggc tgttcatgct gatcaattcg gactcggcgt ccgtgccggg tagcgcagac
     6661 ctggcgctgc tcgacaggct ggaacagctt aacgcgataa ggaagccttt gtagcctatg
     6721 gaaagctcac actatttctg gcttcgctcg accgggtttg cggtgcatca cctgacccgc
     6781 ttggggaaaa tggccgaatt gccgttgctg aaggattttg aaaccgatta tcgctccctg
     6841 aatactctac gcgacagcct gttagagaag tccataagcc actcgtctca ggcctgtcgc
     6901 aagctgatcc gcaagctgaa tgaaaacctg ccgctgcaag tgtctgatct tccagaagcg
     6961 ctgcgtgatg acgcagtgga tgaattggcg cactggaacg agcggcttgg ccggctcaag
     7021 caacgtgtcg aagtggatca ggaatatgcc gtgtttctcg aaagcgcgcg gcaggccctg
     7081 attgatttcg tgaacgatga agacgttgag caggccgtgt tcatttccaa cccgaccgcg
     7141 ctgacccggc ttcgggagct caggcaagag cgccatgcga gaactgacag ccgcaagaag
     7201 cagaaactgc gcctggcctg gagctacgca cagcgattct gttcaaaaaa tgatacgtcg
     7261 agttttttcg gcccgctggc ctgggggcgg tttgatcgta cgcaggtcga gcatgttcgt
     7321 atcacgcagc acggacccgg ctggatcaga gaacgccata cctttttcga gagctgggtt
     7381 gtacagcggc tggtcgagca gttgaatcgc cattgcgttg atgtgcagtt catgccgttg
     7441 caactcaacc cgggctgttt tttgaatcaa gacacgttgc atctgcccgt caacaaacgt
     7501 cgtcaagtca gtgccttgac ggccagagtg ctgggttaca ttcagtgcca gagcgctgtg
     7561 gcaccgaccc tgttcgggtt gcaggccgag ttgcaggatg tcagcgccgg gcaattgcgc
     7621 gacctgatcg atcatctggt cgcccagcag attgtacgtc gcggctggca gatttccccc
     7681 agggaacgaa agcctgttca ggtgctgcac acttttctgg ccgacgcgcg cctgtctgat
     7741 gactttcgca ctcagtggca tgaacgtctg tcgggccttg aagcgattcg gcaagactat
     7801 gcgacaggcg atctggccgt acgcattgcc agcctcgaca agctgaaccg gctgcttggc
     7861 gaagccggcg tggatatttc gcgtgagagc ggcgccatgt atgtcggtcg ctacccggtc
     7921 tacgaggatt gttcgcgcaa tatcgatatc agcctgggtg gcgccttact tgatcaggtc
     7981 aatgccgatc tggcgccgtt gatgcgcatt catcaatggc tgatcaaagc atgcgctcgg
     8041 caactgcatg gtttttacgc tcaggtatgg caacgcctgc aggcagagga cgagcataat
     8101 ccggtgaact tcctggcctt tcttggcgct gtgcaaccag taattgcaca cgccgaggcg
     8161 ggcatcatcg aagaactgga cgcagtgctg gcagacgcct ggcagcaggt cctgagcgat
     8221 aaacacgacc ctgaacaggt gcagttgacc catgaggaca tagagcggct gattgtcgag
     8281 ctgaacacgc gtctggatgt tcggacgttc agcgtatttg gcagccactt tcactctccg
     8341 gatttcctga tttccagtac ctcgacagac gcgctgaacc agggcgacta ctcaatcatt
     8401 ctgggagagg tccatccggg cgtgcacacc ctcagtcagc cggtagccga gcctttcgga
     8461 ccgttcaata aagagatcga gcaggaggtt cggcaaatat tcgacggacc tcgtctggtg
     8521 cttgccgact cgccggacag ttatcagcgt tcgcatatcg attggccttt gctcgagtgc
     8581 taccaacaac tgatactgcc ttctggcggc ggttgcgtgc cggcggatca gcgctttgcc
     8641 gtcggccgtg ctcgtcttgt catgaacgag ggacgtttgc gcgtcgagga tattgccggc
     8701 caattcagcg aagacttggt gtgcgtgtat cccactccta tgcaccgact gggttttgcc
     8761 ttggctggca gcgtcgtggc caagaacgac cgacgccgaa taggcttggg caagaccttg
     8821 tacaaacgcg cctcgtggtg gttcagtcca gagcaactgc cgtgctctga attcagtgtg
     8881 gacaagctcg acgacgtgct ggcatggcga gcgtgggccg tcgagcacgg tttgccccgt
     8941 tatgtgttcg ccaagatcga tatcgaaccc aagccgattt tcattgattt cgataacccg
     9001 ttgtcactcg acggtgtcag taattcgatg aagaaagcgg ggcacgtcaa gttttccgag
     9061 atgtgtcctg ctccggacca actgtggctc gaagaaacgc gcgggcattt ctgttgtgaa
     9121 atacgtacaa cctttaggga caatggagta acgcgtgatg aataacagtt cggccatgga
     9181 cggttcgcag caaaagctca agagcagctt cttcctgctg tttctgacaa ttttcatccc
     9241 ctttggcctg gggcatttcg tttcctacct gtttcgtacc gtcaatgcgg tgatctacgt
     9301 cgatctgcaa accgacctga gcttgcctgc cagcagtctg ggtttgctga ccggcgtgta
     9361 ctttctgacc ttcgccgccg cgcagattcc gcttggcgtg atgctcgacc gttatggccc
     9421 gcgcagcgta caggcgccga tgcttttatt tgcggtcgcc ggttcggtca ttttcagtgt
     9481 ctccagcagc gaggcaggtc tgttgatcgg gcgtggtctg atcggcctgg gcgtggcggg
     9541 ctcgctgatg agtgcgatca aagcatgcgc catctggttg ccggtcgagc gtttgccgct
     9601 gagcaccgcc tgcctgctgt cgattggcgg actgggcgca atggcgtcga ccacgccact
     9661 gcatgcgctg ctgagctggt tgacctggcg cgaagcgttt ctggtcctgg cgctgctgac
     9721 cttttgcgtg gccgtggtca tacatttcag cgtgcccaaa acctaccaga gcaaaaacac
     9781 tcgctacggc gatatgttcg ccgcagtcgg caaactgtac tcgtcctgga cgttctggcg
     9841 tctggcgttg tactcggtgt tcgcacacgc catctacatg tcggtgctgt cattgtggat
     9901 ggggccgtgg ttgcgcgaca tggcaggttt gagtgattcc gcgatggcca gtgtgctgtt
     9961 gttcggggcc atcgcgatag tggcggggtc tctgacgttc ggcgcgatca ccgattacct
    10021 gcgcaggttc ggcgtacagc cgatcatgat ctgtggcacc gggatgctga tctttatcgg
    10081 cttccaggtg ctgatggtca gcgacttgcc ggtatcgcct tatctgattg ccatgggctt
    10141 cagcttcttc ggcacctcga ccaccatgaa ttacgccatc gtcgcgcagt cggtgtcgcc
    10201 agagctggcg ggcagggtga gttcatcctt caatctggtg gtgttcgtgc tcgcgttttg
    10261 cctgcaatgg ctgatgggcg tggtgctcaa tctgtggccg gtcgcgcagg gagcggggca
    10321 tccggctgag gcctatcaat ggtcgttggg gctgatgatt gccctgcaag tgccgggttt
    10381 gctgctttgg ctcagctttc ggccatggca gcgcaaggtc tgaaacgcaa aaccccggcc
    10441 cgagataacc cgggccgggg tttgtttgct ttaccggtgc ggcgatgaat cagctggcgg
    10501 aagccgcgac aggcgcctca agcttttgcc cacccttacg gaacagcacc agcgtcgcaa
    10561 ccagaccgag caccgctgcg ccggtcagcc agatgcctgg cgcagccttg ttgcccagcg
    10621 cgtggatcag gtaggtgcag gccgccggag tgaaaccgcc gaaggttgcg gtcgccaggc
    10681 tgtaggccag cgagaagccg gtggtgcgca cgtcgaccgg catgatctcg gtcaacgcca
    10741 cgaccatcgc gccgttgtag gagccgtaca ggaacgacaa ccacagttcg accatcagca
    10801 ggttactgaa gctcgggttc gcgaccagcc acgacagggc agggtacgca gtggcgatcg
    10861 ccagcacagt ggccgcaatc agcagcggct tgcggccgat acggtccgag aacga
//
