BGC0002666: Legonmycin A biosynthetic gene cluster from Streptomyces sp. MA37
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Location: 1 - 38,533 nt. (total: 38,533 nt).
This entry is originally from NCBI GenBank KM514925.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002666
Short description Legonmycin A biosynthetic gene cluster from Streptomyces sp. MA37
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • other (other)
Loci
KM514925.1
1 - 38533
via
Compounds
  • Legonmycin A
  • Legonmycin B
  • Legonindolizine A
  • Legonindolizine B
Species Streptomyces sp. MA37 [taxonomy]
References
Chemical products information
Legonmycin A Evidence: NMR [1]
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C13H20N2O3
Chemical database entries
PubCHEM
NPAtlas
Legonmycin B Evidence: MS/MS [1], MS/MS [1]
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C14H22N2O3
Chemical database entries
PubCHEM
NPAtlas
Legonindolizine A Evidence: NMR [1], MS/MS [1]
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C14H20N2O3
Legonindolizine B Evidence: NMR [1]
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C15H22N2O3
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIZ66866.1
 1013 - 2959 (-) iron transporter FeoB like protein
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    • AIZ66867.1
    		 3465 - 4730 (+) MFS transporter like protein
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      • AIZ66868.1
      		 4884 - 8591 (+) nitrate reductase like protein
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        • AIZ66869.1
        		 8591 - 10270 (+) putative nitrate reductase
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          • AIZ66870.1
          		 10288 - 10893 (+) putative nitrate reductase
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            • AIZ66871.1
            		 10893 - 11633 (+) putative nitrate reductase
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              • AIZ66872.1
              		 11657 - 12043 (-) hypothetical protein
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                • AIZ66873.1
                		 12401 - 13801 (+) putative cyclic nucleotide-binding protein
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                  • AIZ66874.1
                  		 13801 - 14856 (+) putative terpene synthase
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                    • AIZ66875.1
                    		 14853 - 15713 (+) putative SAM-dependent methlyltransferase
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                      • AIZ66876.1
                      • lgnA
                      		 15740 - 16363 (-) putative thioesterase
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                        • AIZ66877.1
                        • lgnB
                        		 16521 - 18260 (-) nonribosomal peptide synthetase
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                          • AIZ66878.1
                          • lgnC
                          		 18295 - 19473 (-) FAD-dependent monooxygenase
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                            • AIZ66879.1
                            • lgnD
                            		 19470 - 25127 (-) nonribosomal peptide synthetase
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                              • AIZ66880.1
                              		 25495 - 26241 (+) putative hydrolase
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                                • AIZ66881.1
                                		 26238 - 28646 (+) putative glycoside hydrolase
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                                  • AIZ66882.1
                                  		 28671 - 29897 (+) putative hippurate hydrolase
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                                    • AIZ66883.1
                                    		 29915 - 30427 (+) pRNase III regulator YmdB like protein
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                                      • AIZ66884.1
                                      		 30478 - 31110 (-) hypothetical protein
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                                        • AIZ66885.1
                                        		 31148 - 31999 (-) putative urate oxidase
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                                          • AIZ66886.1
                                          		 32220 - 33638 (+) putative monooxygenase
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                                            • AIZ66887.1
                                            		 33635 - 35008 (+) hypothetical protein
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                                              • AIZ66888.1
                                              		 35392 - 36270 (+) putative taurine catabolism dioxygenase
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                                                • AIZ66889.1
                                                		 36432 - 36833 (+) hypothetical protein
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                                                  • AIZ66890.1
                                                  		 36855 - 37970 (-) putative glycine amidinotransferase
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: next

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2024-03-19
                                                    MIBiG v4 annotathon
                                                    • (ID: MMUNJ6X4G367STJ557YTS3XC)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Entry added
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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