LOCUS       BGC0002668             12751 bp    DNA     linear   BCT 17-AUG-2021
DEFINITION  Clostridium estertheticum strain CF004 contig00035, whole genome
            shotgun sequence.
ACCESSION   BGC0002668
VERSION     BGC0002668
KEYWORDS    .
SOURCE      Clostridium estertheticum
  ORGANISM  Clostridium estertheticum
            Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
            Clostridium.
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:10:44
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12751
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1238:7536]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1239..7536
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..12751
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..12751
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002668"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12751
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            32..166
                     /locus_tag="K1726_23300"
     CDS             32..166
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429200.1"
                     /locus_tag="K1726_23300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="MBX4267527.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.8e-17, bitscore:
                     51.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDVKVSKTSEKDKEHITSWSLCTAGCITGRIMGCNK"
     CDS_motif       32..109
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAKFDDFDLDVKVSKTSEKDKEHITS"
                     /locus_tag="K1726_23300_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       110..166
                     /prepeptide="core"
                     /locus_tag="K1726_23300_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="6.40"
                     /molecular_weight="1860.2"
                     /monoisotopic_mass="1858.9"
                     /core_sequence="WSLCTAGCITGRIMGCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDVKVSKTSEKDKEHITS"
                     /leader_location="[31:109](+)"
     gene            225..359
                     /locus_tag="K1726_23305"
     CDS             225..359
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429200.1"
                     /locus_tag="K1726_23305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="MBX4267528.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.8e-17, bitscore:
                     51.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDVKVSKTSEKDKEHITSWSLCTAGCITGRIMGCNK"
     CDS_motif       225..302
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAKFDDFDLDVKVSKTSEKDKEHITS"
                     /locus_tag="K1726_23305_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       303..359
                     /prepeptide="core"
                     /locus_tag="K1726_23305_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="6.40"
                     /molecular_weight="1860.2"
                     /monoisotopic_mass="1858.9"
                     /core_sequence="WSLCTAGCITGRIMGCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDVKVSKTSEKDKEHITS"
                     /leader_location="[224:302](+)"
     gene            418..552
                     /locus_tag="K1726_23310"
     CDS             418..552
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429200.1"
                     /locus_tag="K1726_23310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="MBX4267529.1"
                     /sec_met_domain="TIGR03731 (E-value: 1e-16, bitscore: 50.6,
                     seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDIKVSKTSEKDKEHITSWSLCTAGCITGRIMGCNK"
     CDS_motif       418..495
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /locus_tag="K1726_23310_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       496..552
                     /prepeptide="core"
                     /locus_tag="K1726_23310_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="7.00"
                     /molecular_weight="1860.2"
                     /monoisotopic_mass="1858.9"
                     /core_sequence="WSLCTAGCITGRIMGCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /leader_location="[417:495](+)"
     gene            611..745
                     /locus_tag="K1726_23315"
     CDS             611..745
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429200.1"
                     /locus_tag="K1726_23315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="MBX4267530.1"
                     /sec_met_domain="TIGR03731 (E-value: 1e-16, bitscore: 50.6,
                     seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDIKVSKTSEKDKEHITSWSLCTAGCITGRIMGCNK"
     CDS_motif       611..688
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /locus_tag="K1726_23315_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       689..745
                     /prepeptide="core"
                     /locus_tag="K1726_23315_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="7.00"
                     /molecular_weight="1860.2"
                     /monoisotopic_mass="1858.9"
                     /core_sequence="WSLCTAGCITGRIMGCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /leader_location="[610:688](+)"
     gene            804..938
                     /locus_tag="K1726_23320"
     CDS             804..938
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429200.1"
                     /locus_tag="K1726_23320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="MBX4267531.1"
                     /sec_met_domain="TIGR03731 (E-value: 1e-16, bitscore: 50.6,
                     seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDIKVSKTSEKDKEHITSWSLCTAGCITGRIMGCNK"
     CDS_motif       804..881
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /locus_tag="K1726_23320_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       882..938
                     /prepeptide="core"
                     /locus_tag="K1726_23320_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="7.00"
                     /molecular_weight="1860.2"
                     /monoisotopic_mass="1858.9"
                     /core_sequence="WSLCTAGCITGRIMGCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDIKVSKTSEKDKEHITS"
                     /leader_location="[803:881](+)"
     gene            1239..4382
                     /locus_tag="K1726_23325"
     CDS             1239..4382
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     917.9; E-value: 1.1e-277)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429199.1"
                     /locus_tag="K1726_23325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="MBX4267532.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-138,
                     bitscore: 451.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.2e-17,
                     bitscore: 52.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.8e-39, bitscore:
                     125.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNLYKNVNTFMIRTPLKPIDKYFEFFNNTVDGEKAKEYVKELC
                     NDPVFRESILVSSKSLYDTIINFTNGKDIKKQEYFFRSIYKYLIRMSTRPTPFGLVSGV
                     CFGNYSDKTSITYEDNQFKKFARPDLEWIMEMLKKIEDKYYQALMFKINGYIFIKGDRA
                     VLPHSTLKEDTDNVTEVSIRATNAFKLVCEVAQNTISYSQLKNSLLIKNPGVPEEKINF
                     FLKELINKEYLISNLRPPLTVIDQFDYLIKEIQRCDIDEIILDQLTNIQEKINIYNKTY
                     VGEGESIYIELCKDMNNMEKCKTPLQVDMKLNMKEKTINSKIIDDLNELIHLLLLVSPS
                     SHNSQDYFQIHKMDFMEKYGQEREILLLEMIDNDLGIGAPATYVHPKNNRSKTFNSSDL
                     VNKKVKSYLLQKYIYALDNNYNSIEINDDEIKALDLPQYNYEEIPNSLELNVIVRADSE
                     EEFKKQNLNYHIGPNVGSPQAGKAFGRFSHLMNSPEKFFSELNDNNKALIDSDEYIHCE
                     LVYLGSELRSANVTRNIHCNEYEIALFTNTSKSDEYSLTLDDILIGIEDNVFYAKSKKL
                     NKKLFITVNNMLNSSMAPNAVRFLYDISLDGGKKWFDLPWNDAFYEFPYVPNIKYKNIT
                     ISQEKWILDSINVKGDKKLGFDKFKDSFKLYCSSYKVPQYVYITFADNRILLNLEDNKC
                     LEILYHEFTNNLGDTITLNAYEEEPYNIVNGNDGNYFCELIVPLIKVKSHHPKDIQISN
                     KSSDIPSISPTRLKLPFDDWLYFKLYGTSSSDDELIAFFISEYFHDLVDSQKIEKYFFM
                     RYADPEQHIRLRINAKQSNLLEIYPNLQQWFRSLIEKGIITHIAIDSYDREIERYGGSN
                     LIDVAENVFYADSTITEDILKEKKFNNLTLSDELIGMISIIQYMDQFGLDYENQCDFLE
                     SLVEKTDYREIFKKQRSEFMKLCNSNDNWNGLRQHKEGELLLNILNNRTESIQFYSSEI
                     RKRNNNSLMSEWSILNSVIHLHCNRLFGINREFEKKILTLTRHTLHALRYFKKGSEVE"
     gene            4386..6185
                     /locus_tag="K1726_23330"
     CDS             4386..6185
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 167.3; E-value:
                     7.6e-51)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429198.1"
                     /locus_tag="K1726_23330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="MBX4267533.1"
                     /transl_table=11
                     /translation="MNKVNNEHVSFKDIVKTIKMIPKIFKLISNMDKKSFVIIIALSLI
                     IGLTPILSLFTSQYLLNMIYKKNFYLVMVAFICYFFVSAFDDFISNIKGYYEFKFESVI
                     SYNINVKVMNKCSKLSLKDFENSEIYDKLQRVQEEVAFKPYQVFQSIIQLITAIVTLVS
                     AITILINWKPWVLIVLLIVPAIFSLYFIKISQREFNVEYGRSKERRKSWYLSYILTKDS
                     TFKEIKLYNLSTYILNKFKDINKTFIKQDIKLFKRRSIFTLSFGFIEQICTSSILLIII
                     YSALLNKMLIGNVVGFIKAISLTESNTKSIINTMYSLYKNNLYINQLFEFLALPEEQSN
                     KTLIGNNIDFIENIKIKNLTFKYPTASKEVLKNINLDIKKGERIAIVGQNGSGKSTLVK
                     LLLKLYNTDNDSIFYNNKSINHYNTEQMQSCIGVLFQDFIKYELTLKENVGFGNIGKIN
                     EKHEMRGALEKAQVNFIDDLDAQLGLWFDDGIQFSGGQWQKIALARAFFRNASLYVLDE
                     PSSALDPIAEKQIIDMFIEMTKDKIGIFISHRLSTAMLADKIVVMDKGRISGVGTHDVL
                     LKTNAIYKEMYELETIKDINLAS"
     gene            6220..7536
                     /locus_tag="K1726_23335"
     CDS             6220..7536
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     392.6; E-value: 3.3e-119)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429197.1"
                     /locus_tag="K1726_23335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="MBX4267534.1"
                     /sec_met_domain="LANC_like (E-value: 1e-74, bitscore:
                     241.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKNIDNLVKNIAQKLKDFDYVENVINKKSNYRNINGLKINPYD
                     EMALSSGLPSLCMLYGEMNEQYPKEDWDIIDHQYIKILGDTITKNGIEELSMFSGAAGI
                     GLSIVCSSKQRERYTSFISNINEFIKSNIKEFMDKIKANTYCNITNYDVISGVSGIASY
                     CMLFPQDEGMTDILKEIVTYIIDICRDKNIENISVPGWYIPSENLFTKNDKQQWPKGCF
                     NIGLAHGIPGILIILCNALKLGICLDGQSDCIRKIGDFLIRFRRQDNNGCYWGCIVSLD
                     EYIDNTIDDPYFRDAWCYGTPGVAYSLLLAGKALNNQSYITVAIEGMQSSIKRLKEICS
                     PTFCHGLSGEMYIAYRFYELTNLAEFKGAYIELSNKLISFYDDEAPFGFYDIEIANGKC
                     ENYNYIGLIDGTVGILLTLMAIQNGKKTPWDCAFLLSDI"
     gene            7591..9672
                     /locus_tag="K1726_23340"
     CDS             7591..9672
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017368.2"
                     /locus_tag="K1726_23340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="immune inhibitor A"
                     /protein_id="MBX4267535.1"
                     /transl_table=11
                     /translation="MYKIKNVILFVILILLNSFIIMGFTNIKIVNALTINTEKNITKDK
                     TLVLMIDFPDLKFNTLNKNDTSMYYKDFNKNHYKDMLFNKKGYLGPQGQNLISMRQYYN
                     IQSNSTYDPDGKVMGTYTAKHKASYYGKDDLPNERSDINVEELVKEALTQLSKDKTINL
                     AEFDQKDTEDIDNDGNIDEPNNIIDNLIIIHAGMGQEKGGGKLKDNAIASHSSKIYADN
                     GVSPYKIPNTKYSDLRYTIQPEDGTVGVFAHEFAHTLGYKDEYDTSSSSIGAPIAWWSI
                     MANGSDAGKIPGTEPTGFSPYAKEFFQNKYGGDWLKPAVVNLKDLSNTPSQFTLDQASI
                     RGKNNTAVKIMLPKKETIINKPAQGKYEYFSGTGNNLNNSMSTKIDLSKCKSAKFTFKT
                     WYITEKDSDYASVNVKIQGENNWINIPGNITTIIDPKGNCPKNSITGDSKGFKDASFDL
                     SEFCGKKIDICFKYISDASLNKDGFYVDDIKVETDKGTILKDNAENSKSKFDLQGFLKS
                     DGLKHTDQYYLLEWRNQTGIDSGLGNIKTSIGTISYDPGLVIWYVDKAYEDNWVGETSV
                     GGHPGYGFLGIVDADQETITTNTKLPVPTEFQMHDAAFSLKPTSKFTFNIPNTDLTISD
                     NHSCNNNIFKDSYSYLNNVVPSSGRYLPDFGLSICVKSQSEDNSCGIIEISKTNLANR"
     gene            10046..10753
                     /locus_tag="K1726_23345"
     CDS             10046..10753
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 181.5; E-value:
                     3.4e-55)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405367.1"
                     /locus_tag="K1726_23345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="MBX4267536.1"
                     /transl_table=11
                     /translation="MDNYILQTKNLCKTFKKQRAVNNISLSIKENSVYGLLGPNGAGKS
                     TILKMITGMLHPTSGEIIFEGHSWSRKDLSNIGVLIESPPLYENLTAVENLKVRTILLG
                     LPDSRIKEVLETVALTNTGKKQAGHFSMGMKQRLGIAIALLNKPKLLILDEPTNGLDPI
                     GIQDLRELIRSFPAQGMTVILSSHILSEVELIADNIGIISNGVLGYQGKINRGEDLEVL
                     FTEVVKKNREMVS"
     gene            10753..11478
                     /locus_tag="K1726_23350"
     CDS             10753..11478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011949125.1"
                     /locus_tag="K1726_23350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="MBX4267537.1"
                     /transl_table=11
                     /translation="MLEYIQAENLKCKRTFLKKLILFAPMVTFLIAYISGTWFQVNAFN
                     SWYMMILPGYISLMAVMTNEKEQKKLRYRAVFGLPISLKKIWISKVLVNGIYMTLSCIF
                     LSVGIILAGYKFSVTVPFSRALIAAGLIAVTSLWQIPLCMFLAKKLGMLGTVLINVCGS
                     FILSALTAITSLWWICPYSWTARIMCPILGNLPNGNLAKIGDPLLNPVVIPIGIIMSAI
                     IFVLLVVVSANWFSKQEVN"
     gene            11480..12223
                     /locus_tag="K1726_23355"
     CDS             11480..12223
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520644.1"
                     /locus_tag="K1726_23355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="MBX4267538.1"
                     /transl_table=11
                     /translation="MISLIRCIKSDLYKLRHTSILWIHLLIPLAAAFIFSLYYHITSRN
                     SVMDIKVYLEALAIAFPLLIGLISGIVIEQEEQAGNFQVMLATSRSKCTMYLSKLILLL
                     LLGSFSIALAVGVFAVGFQGVSHLFYLKAAAALVIGNAFLYILHVFISLEFGKGASTGL
                     GVAGSLISALMLTGLGDYIWHFMPWAWSVRLCDSMVTKLDYPAFSAQIALDMQKGSVVM
                     LFAIGIAFFASLFWFKKWEGRKSYN"
     gene            12239..12748
                     /locus_tag="K1726_23360"
     CDS             12239..12748
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033433.1"
                     /locus_tag="K1726_23360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="MBX4267539.1"
                     /transl_table=11
                     /translation="MKTKRTLVSLLAVLFCTIVIGYFAKDTIIKKVMHYQIKDKIVCKV
                     NAKNATQISYKEVMYQISNVSLDKSKIGGWNGIINQVVVIDKNNCILEQKEIDSSAQLT
                     IKDIKHNLPKDAKFIVPFQSVCSIKGTDNKDAIAVQVNNKFYKTVPVGSTSTDKTAIKL
                     APAEQK"
ORIGIN
        1 aaaaaataaa atttaaaagg agattttaaa aatggctaaa ttcgatgatt ttgacttaga
       61 cgttaaggtt agtaaaacaa gtgagaagga taaggaacat atcacaagct ggtctttatg
      121 caccgctggt tgtattactg gaagaataat gggttgcaat aaataatggg ttgcaataaa
      181 taacagattc aataaaaaat aaaatttaaa aggagatttt aaaaatggct aaattcgatg
      241 attttgactt agacgttaag gttagtaaaa caagtgagaa ggataaagaa catatcacaa
      301 gttggtcttt atgcactgct ggttgtatta ctggaagaat aatgggttgc aataaataat
      361 aggttgtaat aaataataga ttcaacaaaa aataaaattt aaaaggagat tttaaaaatg
      421 gctaaattcg atgattttga cttagatatt aaggttagta aaacaagtga gaaggataag
      481 gaacatatca caagttggtc tttatgcact gctggttgta ttactggaag aataatgggt
      541 tgcaataaat aatgggttgc aataaataac agattcaaca aaaaataaaa tttaaaagga
      601 gattttaaaa atggctaaat tcgatgattt tgacttagat attaaggtta gtaaaacaag
      661 tgagaaggat aaggaacata tcacaagttg gtctttatgc actgctggtt gtattactgg
      721 aagaataatg ggttgcaata aataatgggt tgcaataaat aacagattca acaaaaaata
      781 aaatttaaaa ggagatttta aaaatggcta aattcgatga ttttgactta gatattaagg
      841 ttagtaaaac aagtgagaag gataaagaac atatcacaag ttggtcttta tgcactgctg
      901 gttgtattac tggaagaata atgggttgca ataaataatg ggttgtaata aataatagat
      961 tcaacaaaaa ataaatcatt tataaatcat catttataaa taataaagga taacaagatt
     1021 tgaatgattt attttaaatc attgttatcc tttaaaatta taaatagata aaatttgtac
     1081 ataatttaac gatattttgc aaggaaaatc atccattata taagtggaga ccagccacca
     1141 cagaaaaaaa gaatctttta gtgggcgttg aaatttcttt cgtaagtcgt taatatggca
     1201 ctttctgtgc taatttcata attttgtgag gtgtatccat gaaaaataat ttatataaaa
     1261 atgtaaatac atttatgatc agaactccat taaaacctat agataagtat tttgaatttt
     1321 ttaataatac tgttgatggt gaaaaagcaa aagaatatgt gaaagagctt tgtaacgatc
     1381 cagtttttag agaaagtata ttggtatcaa gtaaaagttt atatgacaca ataattaatt
     1441 ttactaatgg aaaagatatt aaaaagcaag agtacttttt tcgctcaata tataaatatt
     1501 taattaggat gagtacacga ccaactccgt ttggattagt ttctggtgta tgttttggaa
     1561 attattctga taaaacttct attacttacg aagataatca atttaaaaaa ttcgcaagac
     1621 ctgatttaga atggattatg gaaatgttga aaaaaataga agataaatat tatcaagcat
     1681 taatgtttaa aataaatgga tatattttca ttaaaggtga tagagctgtg ctcccccatt
     1741 ctacattaaa agaagatact gataatgtaa ctgaagttag tattagagca acaaatgctt
     1801 tcaaattagt gtgtgaggta gcacaaaaca ctatttccta tagtcaatta aaaaatagtt
     1861 tattaataaa aaatccaggg gtaccagaag agaaaattaa ttttttctta aaagaattaa
     1921 taaataaaga atatttaata tctaatttac gtcctccact aacagtaatt gatcagtttg
     1981 attatttaat taaggaaata caacggtgtg atatagacga aataatatta gatcaactaa
     2041 ctaatattca agaaaaaata aacatttata ataaaacgta tgttggtgag ggcgagagca
     2101 tttatataga gttatgcaag gatatgaata atatggaaaa atgtaaaacg ccattgcagg
     2161 ttgatatgaa attgaatatg aaagagaaga caattaactc aaaaataata gatgatttaa
     2221 atgaattgat acatctattg cttttagtat caccgtctag tcataattca caagattatt
     2281 ttcaaataca caaaatggac tttatggaga agtatggtca agaaagagaa atccttttac
     2341 tggaaatgat cgataatgat ttgggtatag gagcaccagc aacttatgtt catcctaaaa
     2401 acaatagatc gaaaactttt aattctagcg atttagttaa taagaaggtt aaatcctatt
     2461 tgttacaaaa atatatatat gcattggata ataattacaa cagcatagag ataaatgatg
     2521 atgagataaa agcgttagat ttaccacagt ataattatga agaaattcct aattcattag
     2581 aactaaatgt gatagtaaga gcagactcag aagaagaatt taaaaaacaa aacttaaatt
     2641 atcacatcgg tcctaatgta ggttcaccac aagcaggtaa agctttcgga agattttctc
     2701 atttaatgaa tagtccagaa aagttttttt cagaattaaa tgataataat aaagcattaa
     2761 ttgatagtga tgaatatatt cactgtgagc ttgtttatct tggaagtgaa cttagaagtg
     2821 caaatgtaac tagaaatatt cattgtaatg aatatgagat tgccttgttt acaaatacct
     2881 ctaaaagtga tgaatattca ttaaccttag atgatatttt aataggaatc gaagataatg
     2941 ttttttatgc taaaagcaaa aagctcaaca aaaaattgtt tattacggta aacaatatgt
     3001 tgaattcatc tatggcacca aatgcagtta gatttttgta tgatataagt ttagatggag
     3061 ggaaaaaatg gtttgactta ccttggaatg atgcatttta tgagtttcct tatgttccta
     3121 atattaaata taagaatata actatatcac aagaaaaatg gatacttgac tctataaatg
     3181 ttaagggaga taaaaaatta gggtttgata aatttaaaga ttcttttaaa ttatattgta
     3241 gctcgtataa agttcctcaa tatgtgtata ttacattcgc tgataatagg atattactca
     3301 acttagagga taataaatgt cttgaaatac tctaccatga gtttacaaat aatttaggtg
     3361 atactattac ccttaatgct tatgaagaag agccttataa tattgtaaat ggtaatgatg
     3421 gaaactattt ttgtgaatta attgtaccct taataaaagt taaaagtcat catccaaaag
     3481 atatacaaat atctaataaa tcaagtgaca taccaagcat atcaccaact agattaaaac
     3541 ttccttttga tgattggttg tactttaaat tatacggaac tagttctagt gatgatgagt
     3601 taattgcatt tttcatatca gaatatttcc atgatttagt agatagtcag aaaatagaaa
     3661 aatatttctt tatgagatat gcagatccag agcaacacat acgtttaagg attaatgcaa
     3721 aacaatctaa tcttttagag atctatccaa atttgcagca gtggtttcgt tcattaattg
     3781 aaaaaggaat aataacccac attgctattg actcttacga tagagaaata gagcggtatg
     3841 gagggagtaa tctaatagat gtggcagaaa atgtatttta tgctgatagc actataacag
     3901 aagatatatt aaaggaaaag aaatttaata atcttacttt gagcgatgag ttaataggta
     3961 tgatatctat tatacagtat atggatcaat ttggtttaga ttatgagaat caatgtgatt
     4021 ttttagaatc tttggttgaa aaaactgatt atagagaaat ctttaaaaaa caacgttctg
     4081 aatttatgaa attatgtaat agtaatgata actggaacgg attaagacag cataaggaag
     4141 gcgaactatt attaaacatt cttaataata gaactgaaag tatacaattt tatagtagtg
     4201 aaataagaaa aagaaataat aattcgctga tgtctgaatg gtcaatttta aatagtgtta
     4261 ttcatttaca ttgtaataga ttgtttggga tcaatagaga atttgaaaag aaaattttaa
     4321 cattaacacg acatactcta catgcactac gctattttaa aaaaggaagt gaggttgaat
     4381 aataaatgaa taaagttaat aacgaacatg tctcatttaa agatattgta aaaacaatta
     4441 aaatgattcc taaaatattt aagttaataa gcaatatgga taaaaaatca ttcgtaataa
     4501 ttattgctct tagcttaata ataggtttga cccctatact ctcattattt acttctcaat
     4561 atttactaaa tatgatttat aaaaagaatt tctatttagt tatggtagcc tttatatgtt
     4621 atttcttcgt tagtgcattc gatgatttta tctcaaatat taaaggctat tatgaattta
     4681 agttcgaatc agttatatcc tataatatta atgttaaagt tatgaacaag tgcagtaagc
     4741 tgtctcttaa agattttgaa aattcagaaa tttacgataa acttcaaaga gttcaagaag
     4801 aagtagcatt taaaccttat caagtatttc aatctataat acaattaatt actgctatag
     4861 ttacactcgt atcagcgata acaattttga taaattggaa accttgggtt ttaattgttt
     4921 tattaattgt gcctgctatt ttttctcttt attttattaa aatatcacaa agagaattca
     4981 atgttgaata tgggcgcagt aaggagagaa ggaagtcctg gtatctatct tatatattaa
     5041 ctaaagattc gacttttaaa gaaataaaat tatacaacct atcaacttat attctcaata
     5101 aatttaagga tattaataaa acctttatta aacaagatat taaattattt aaaaggagaa
     5161 gtattttcac attatcattt ggatttatag agcaaatatg tacgagtagt attttactaa
     5221 ttattatata ttctgcttta ttaaataaaa tgttaatagg taatgttgtt ggttttatta
     5281 aagcaataag tttaactgaa agtaacacta aatcaataat taatactatg tattctctat
     5341 ataaaaataa tttatatata aaccagttgt ttgaattttt agctttacca gaagagcagt
     5401 caaataaaac tttaataggt aataatatag actttattga aaatatcaaa attaagaatt
     5461 taacctttaa atatcctact gcttctaagg aagtattaaa aaatatcaac cttgatatca
     5521 aaaaaggaga aagaattgct attgttggac aaaatggttc tggtaaaagt acacttgtaa
     5581 aacttctatt gaaactttac aacaccgata atgattcgat tttttataat aacaaatcta
     5641 taaatcacta taatacagaa caaatgcaaa gttgcattgg tgtattattt caagatttta
     5701 ttaaatatga attaacctta aaagaaaatg taggttttgg gaatattgga aaaatcaatg
     5761 aaaagcatga aatgagaggg gctttagaaa aggcacaggt taattttatt gatgatttag
     5821 atgcacagct tgggttatgg tttgatgatg gtattcaatt ttctggagga cagtggcaaa
     5881 aaattgcttt agcaagagcc tttttcagaa acgcttcatt atatgtgtta gatgaaccga
     5941 gttcggcgtt agatccaatc gcagaaaaac aaattataga tatgtttatt gaaatgacca
     6001 aagataagat aggaatattt atttcccata gattatctac cgcaatgtta gcagataaaa
     6061 ttgttgtaat ggataaaggg cggataagtg gcgttggaac tcatgatgtt ttattaaaaa
     6121 ccaatgctat atataaggaa atgtatgaat tagaaactat aaaagacatt aatttagcta
     6181 gttaaaatta ttaatattat aaaatatgaa gaggtgatta tattgaaaaa aaacattgat
     6241 aacttggtta aaaatatagc tcaaaaactg aaagattttg actacgtaga aaatgtgata
     6301 aataaaaaaa gtaattatag aaatatcaac ggtttaaaga taaatccata cgatgaaatg
     6361 gctttgagta gtggattgcc ttctttgtgt atgttatatg gtgaaatgaa tgaacaatat
     6421 cctaaagaag attgggatat tattgatcac cagtatatta aaatattagg tgatacgata
     6481 acgaaaaatg gaattgaaga gctgtccatg tttagtggtg ctgcaggtat aggcctttct
     6541 atagtatgtt catccaagca aagagaaagg tatacttcct ttatatccaa tattaatgag
     6601 tttataaaaa gtaatataaa agagtttatg gataaaatta aagccaatac ctactgcaat
     6661 ataactaatt atgatgtaat ttcgggagta tcaggaatag ctagttattg catgttattt
     6721 ccacaagatg aaggcatgac agacatatta aaagaaatag taacctatat tattgatatt
     6781 tgtagggata aaaatataga aaatataagt gtaccaggct ggtatattcc ttcagaaaat
     6841 ttgttcacaa aaaatgacaa acaacaatgg ccaaaaggat gctttaatat tggattagct
     6901 catggtattc caggtatatt aattattcta tgtaatgcgc ttaagcttgg catttgctta
     6961 gatggccaaa gtgattgtat tagaaaaata ggagattttc ttatacgatt tcgtagacag
     7021 gacaataatg gttgttattg gggttgtatt gtctccttag atgagtatat tgacaatacc
     7081 atagatgatc catactttag agatgcttgg tgctatggta caccaggagt tgcatattcc
     7141 ttacttttag caggaaaagc tttaaataat caatcctata taaccgtcgc tattgaagga
     7201 atgcaaagct caattaaaag acttaaagaa atatgttcgc caaccttttg tcatggatta
     7261 tccggagaaa tgtatatcgc ttatagattt tacgaattaa caaacctagc ggaatttaaa
     7321 ggtgcatata ttgagctttc aaataaacta attagttttt atgatgatga ggctccattt
     7381 ggcttttatg atatagaaat agctaatggt aaatgtgaga attataatta tattggctta
     7441 atcgatggaa ctgttggcat tttattaaca ttaatggcaa tacaaaacgg aaaaaaaaca
     7501 ccttgggatt gtgcttttct tttatcagat atatgatttg tgagcttatt aagaatagct
     7561 tttatccttt aaggaggtgc gatgtaaaga atgtataaaa ttaagaatgt aattttattt
     7621 gtaatcttaa tattactgaa cagttttata ataatgggat tcacgaacat taaaatagtt
     7681 aatgccctta ctataaatac tgaaaaaaat attacaaaag ataagacgtt agtgctaatg
     7741 atcgattttc ctgatttgaa atttaatacg ttaaataaaa atgataccag tatgtactat
     7801 aaagatttta ataaaaatca ttataaagat atgctgttta ataagaaggg ctatctagga
     7861 ccacagggcc aaaacctcat ttcaatgagg caatattata atattcaatc aaacagtact
     7921 tatgatcctg atggaaaagt tatgggaaca tatactgcaa aacataaagc atcatattat
     7981 gggaaggatg atctccctaa tgaaagatca gatataaatg tagaagaatt agttaaagaa
     8041 gcattaacac aattatctaa agacaaaaca attaatctag ctgaatttga tcaaaaagac
     8101 acagaagata ttgataatga tggaaatata gatgaaccta ataacattat tgataatttg
     8161 ataattattc atgcaggtat ggggcaagaa aaaggtggcg gtaagctaaa agataatgct
     8221 attgcgtccc atagttcaaa aatatatgca gataatggag tatcgcccta taaaattcct
     8281 aacacaaaat atagtgatct aagatatact attcaacctg aagatggtac agttggagtt
     8341 ttcgcccacg agtttgctca tacgttaggt tataaagatg aatatgatac tagtagttca
     8401 agtattggtg cgcctatagc atggtggtct ataatggcta atggcagcga tgcgggtaaa
     8461 attccaggaa cagaacctac aggttttagc ccatatgcaa aagaattttt tcaaaataaa
     8521 tacggtggag attggttaaa accagcagtt gttaatttaa aagatttatc taatacccct
     8581 agtcaattta cattagatca ggctagtatt agaggtaaaa acaatactgc tgtaaaaata
     8641 atgctgccta aaaaagaaac aattattaat aaaccagcac aaggaaaata tgaatatttt
     8701 agtggtactg gaaataactt aaataattct atgtcaacta aaattgattt atcaaagtgc
     8761 aaaagtgcaa aatttacatt taaaacatgg tacataactg aaaaggattc tgattatgcc
     8821 tccgttaatg taaaaatcca gggagaaaat aattggatca acattccagg aaatattact
     8881 acaattattg atccaaaagg aaattgtcct aaaaatagta ttaccgggga ttccaaaggg
     8941 tttaaagatg caagttttga tttatctgaa ttctgtggta aaaaaataga tatatgtttt
     9001 aaatatattt cagatgcttc tctaaataaa gatggttttt atgtagatga tattaaagtt
     9061 gaaacagata aagggaccat tttaaaagat aatgctgaaa attctaaatc taaatttgat
     9121 ttacagggtt ttctaaaatc tgatggttta aaacatactg accagtatta tttattagaa
     9181 tggagaaatc aaactggtat agattcagga ttaggaaata ttaaaacttc aattggcaca
     9241 atatcttatg atcctgggtt agtaatatgg tatgtagata aagcttatga agataactgg
     9301 gtaggagaaa cttcggtagg gggacatcct ggctatggtt ttctaggaat tgttgatgcg
     9361 gatcaagaaa ctataacaac aaacacaaaa cttccagttc ctacagaatt tcaaatgcat
     9421 gatgcagcgt ttagtttaaa acccacttca aaattcacat ttaatatacc aaatactgat
     9481 ttaacaattt cagataatca tagttgcaat aataatattt ttaaagatag ttatagttat
     9541 ttaaataacg ttgtaccatc aagtggtagg tatctacctg atttcggttt gtcaatatgt
     9601 gtaaaaagtc aaagcgaaga taactcttgt ggaataatcg aaatatctaa aacaaacttg
     9661 gctaatcgat aattattttg tattaaagca tctcctgtgg aactgcaaca tatccgcagt
     9721 agatgcttta atgattttaa tagcaaataa aaaagaaata ttagtaatta ctgatattaa
     9781 aaacgtaatt tctgaaaaat ttaggctttg ctcttctttt tttataagta ttataccaag
     9841 ttttacaatt ttaagaagcg attgatttta aatggtatat ttatctaaag aaaggaacta
     9901 aaaggaggta cctaaatgaa aatagcttta aataaattac atactaaagt gattaatttt
     9961 aatcattaaa aaaagaaaga attttttaaa tacttataaa tgtaattcat ggtttatatt
    10021 attaactcga gaaaggaaga tgaatatgga taattatatt ttacaaacaa aaaatctttg
    10081 caagactttt aaaaaacaac gtgcagtaaa caatatatcc ttatcaatta aagaaaattc
    10141 tgtttatgga ttgctaggac caaatggggc cggaaaatca actatattaa aaatgattac
    10201 gggaatgctt catccaacat ctggagaaat tatatttgag ggacattcgt ggagtaggaa
    10261 ggatctttct aatataggag ttttgattga atctccgcct ctttatgaaa atcttacggc
    10321 ggttgaaaac ctcaaagtac gaactatcct tttaggactt ccagattctc gtattaaaga
    10381 agtactagaa acggtggctt tgacgaatac aggaaaaaag caggcagggc acttttctat
    10441 ggggatgaag caaaggcttg gaatcgcaat tgcactacta aataaaccta aattactaat
    10501 tttggatgaa cctacaaacg gtcttgatcc tattgggatt caagacttaa gagaactaat
    10561 acgttcattc ccagcgcagg gaatgacagt catcctatct agccatatat tatctgaggt
    10621 tgaacttatt gcagataaca ttggtattat aagcaatggg gtactcgggt atcaaggcaa
    10681 aattaatcgt ggtgaagatt tggaagtgct tttcacagag gttgtgaaaa agaacaggga
    10741 gatggtttca tgatgctcga atatatacaa gctgaaaatt tgaaatgcaa gagaacattt
    10801 ctgaaaaaat tgattttgtt tgcacctatg gttacgtttc tcattgcata tatatctgga
    10861 acatggttcc aagttaatgc atttaattcg tggtacatga tgattttgcc gggatatatt
    10921 tcactaatgg cagtgatgac taatgaaaaa gagcaaaaaa agttacgcta tagagctgta
    10981 tttggtttac caatttcact aaaaaaaata tggatttcaa aagttttggt aaatgggatt
    11041 tatatgacgc tctcatgtat atttttatca gtaggaatta ttttagcagg ctacaaattc
    11101 tccgtcactg taccattttc tagggcactt atagcagctg gtttgattgc agttacatct
    11161 ttatggcaga ttccactttg tatgttttta gcgaagaaac tgggaatgct aggaactgtt
    11221 ttaataaacg tttgcggtag ttttatatta agtgctttga ccgcaataac atcattgtgg
    11281 tggatttgtc cttatagctg gacagctcgt attatgtgtc caattcttgg taatttacca
    11341 aatggaaatt tggcaaaaat cggggatccg ttactaaatc cggttgtaat tccaattgga
    11401 atcattatgt ccgctattat atttgtcttg ttagttgttg tttccgctaa ttggttttca
    11461 aaacaggagg ttaattaata tgatttcttt aatcagatgt ataaaatcgg atctttacaa
    11521 attaagacat acttctattt tgtggattca tttgctgatt ccactagcag ccgcgttcat
    11581 attttcatta tattatcaca taacatcaag aaattcagtc atggacataa aagtgtatct
    11641 ggaggctctg gcaattgctt ttcctttact tatagggtta attagtggga tagtaattga
    11701 gcaggaggaa caggctggaa atttccaagt aatgctagct acttcaagat caaaatgtac
    11761 catgtattta agcaagctaa ttcttttact tttattggga agtttttcta tagcacttgc
    11821 tgtaggagta tttgcagttg gattccaagg ggtttctcac ttattttact taaaagcagc
    11881 tgcagcattg gttataggaa atgcatttct ctatatctta catgtgttca ttagtctaga
    11941 atttggaaag ggagcctcta cagggcttgg agttgcagga agtttgattt cagctcttat
    12001 gctcacaggt cttggtgatt atatatggca ctttatgcca tgggcatgga gtgtgaggct
    12061 ttgcgatagt atggttacca agttggacta tcctgctttc agtgctcaaa tagcacttga
    12121 tatgcaaaag ggatcagttg taatgttatt tgcaatagga attgcctttt ttgctagttt
    12181 attttggttc aaaaagtggg aaggaagaaa atcatataat taaaaagggg tttttattat
    12241 gaaaacaaaa agaacattgg tctctttgct tgcagttttg ttttgtacaa tagtaatagg
    12301 gtattttgca aaagatacta taattaaaaa agtaatgcat tatcaaatta aagataaaat
    12361 tgtttgcaag gtcaatgcta aaaatgctac tcaaataagt tataaagaag taatgtatca
    12421 aatttcaaat gtttcattgg ataagtccaa aattggagga tggaatggaa ttattaacca
    12481 agtagtagtt attgataaaa ataattgtat acttgaacaa aaggaaattg attcatctgc
    12541 ccagttaacg ataaaggata ttaagcataa tcttcctaaa gatgcaaaat ttattgtacc
    12601 ttttcaaagt gtttgctcaa taaaaggtac agataataaa gacgccattg ccgtccaagt
    12661 caataacaaa ttttataaaa ctgttccagt aggaagcacg tctactgaca aaacagccat
    12721 caaattagct cctgcagagc aaaaataaag t
//
