BGC0002671: kendomycin B biosynthetic gene cluster from Verrucosispora sp.
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Location: 1 - 79,937 nt. (total: 79,937 nt).
This entry is originally from NCBI GenBank MZ222135.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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TTA codons
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General information about the BGC

MIBiG accession | BGC0002671
Short description | kendomycin B biosynthetic gene cluster from Verrucosispora sp.
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- PKS (Unknown)

Loci
MZ222135.1
1 - 79937
via Heterologous expression, Knock-out studies
Compounds

- kendomycin B

Species Verrucosispora sp. [taxonomy]
References

- [1] Identification and Heterologous Expression of the Kendomycin B Biosynthetic Gene Cluster from Verrucosispora sp. SCSIO 07399. Chen, J et al., Marine Drugs (2021) DOI:10.3390/md19120673
- [2] Identification and Heterologous Expression of the Kendomycin B Biosynthetic Gene Cluster from . Chen J et al., Mar Drugs (2021) PMID:34940672

Chemical products information
kendomycin B Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
UHY14116.1 | 1 - 2337 (+) | DUF262 domain-containing protein |  |  | copy AA seq copy Nt seq
UHY14117.1 | 2725 - 3012 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
UHY14139.1 kmy1 | 3334 - 3597 (-) | transposase |  |  | copy AA seq copy Nt seq
UHY14118.1 kmy2 | 4409 - 4645 (+) | transposase |  |  | copy AA seq copy Nt seq
UHY14119.1 kmy3 | 4611 - 5738 (+) | transposase |  |  | copy AA seq copy Nt seq
UHY14120.1 kmy4 | 6190 - 8955 (+) | transcriptional regulator |  |  | copy AA seq copy Nt seq
UHY14140.1 kmy5 | 9015 - 9839 (-) | NAD(P)-dependent oxidoreductase |  |  | copy AA seq copy Nt seq
UHY14121.1 kmy6 | 9931 - 10548 (+) | transcriptional regulator |  |  | copy AA seq copy Nt seq
UHY14122.1 kmy7 | 10685 - 10909 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
UHY14123.1 kmy8 | 10964 - 11413 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
UHY14124.1 kmy9 | 11413 - 12966 (+) | FAD-dependent oxidoreductase |  |  | copy AA seq copy Nt seq
UHY14125.1 kmy10 | 13067 - 24646 (+) | PKS I |  |  | copy AA seq copy Nt seq
UHY14126.1 kmy11 | 24683 - 31114 (+) | PKS I |  |  | copy AA seq copy Nt seq
UHY14127.1 kmy12 | 31139 - 41179 (+) | PKS I |  |  | copy AA seq copy Nt seq
UHY14128.1 kmy13 | 41208 - 42380 (+) | FAD-dependent monooxygenase |  |  | copy AA seq copy Nt seq
UHY14141.1 kmy14 | 42448 - 43908 (-) | benzaldehyde dehydrogenase |  |  | copy AA seq copy Nt seq
UHY14142.1 kmy15 | 43929 - 45584 (-) | benzoylformate decarboxylase |  |  | copy AA seq copy Nt seq
UHY14143.1 kmy16 | 45589 - 46923 (-) | dioxygenase |  |  | copy AA seq copy Nt seq
UHY14144.1 kmy17 | 46920 - 47603 (-) | enoyl-CoA hydratase/isomerase |  |  | copy AA seq copy Nt seq
UHY14145.1 kmy18 | 47655 - 48773 (-) | PKS III |  |  | copy AA seq copy Nt seq
UHY14129.1 kmy19 | 49095 - 62579 (+) | PKS I |  |  | copy AA seq copy Nt seq
UHY14130.1 kmy20 | 62585 - 67507 (+) | PKS I |  |  | copy AA seq copy Nt seq
UHY14131.1 kmy21 | 67539 - 68324 (+) | thioesterase |  |  | copy AA seq copy Nt seq
UHY14132.1 kmy22 | 68324 - 70258 (+) | methylmalonyl-CoA mutase |  |  | copy AA seq copy Nt seq
UHY14133.1 kmy23 | 70255 - 72426 (+) | methylmalonyl-CoA mutase |  |  | copy AA seq copy Nt seq
UHY14134.1 kmy24 | 72429 - 73460 (+) | methylmalonyl-CoA mutase-associated GTPase |  |  | copy AA seq copy Nt seq
UHY14135.1 kmy25 | 73594 - 74895 (+) | propionyl CoA carboxylase |  |  | copy AA seq copy Nt seq
UHY14146.1 kmy26 | 74974 - 76617 (-) | PQQ-dependent enzyme |  |  | copy AA seq copy Nt seq
UHY14147.1 kmy27 | 76757 - 77281 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
UHY14148.1 kmy28 | 77401 - 77778 (-) | DoxX family protein |  |  | copy AA seq copy Nt seq
UHY14138.1 kmy29 | 77898 - 78704 (-) | enoyl-CoA hydratase/isomerase |  |  | copy AA seq copy Nt seq
UHY14136.1 | 79095 - 79718 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
UHY14137.1 | 79734 - 79937 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 2

Date
Changes
Submitters
Reviewers
2024-07-31
MIBiG v4 annotathon

- (ID: X3QVFXOIMTNXSB4JQGP4RI6A)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2022-09-15
Entry added

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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